1175:'''Tizoxanide''', also known as '''desacetyl-nitazoxanide''', is a ] and an ] that occurs as a ] of ] in humans through hydrolysis.<ref name="pmid17888524">{{cite journal |vauthors=Korba BE, Montero AB, Farrar K, etal |title=Nitazoxanide, tizoxanide and other thiazolides are potent inhibitors of hepatitis B virus and hepatitis C virus replication |journal=Antiviral Res. |volume=77 |issue=1 |pages=56–63 |date=January 2008 |pmid=17888524 |doi=10.1016/j.antiviral.2007.08.005 }}</ref> Tizoxanide may undergo further metabolism via conjugation into ].<ref name="FDA Nitazoxanide">{{cite web|title=Nitazoxanide Prescribing Information|url=http://www.alinia.com/images/Alinia-Prescribing-Information.pdf|publisher=Romark Pharmaceuticals|access-date=3 January 2016|pages=1–5|date=August 2013}}</ref><ref name="Primary: Kinetics and OD">{{cite journal | vauthors = Stockis A, Allemon AM, De Bruyn S, Gengler C | title = Nitazoxanide pharmacokinetics and tolerability in man using single ascending oral doses | journal = Int J Clin Pharmacol Ther | volume = 40 | issue = 5 | pages = 213–220 | date = May 2002 | pmid = 12051573 | doi = 10.5414/cpp40213}}</ref>
148:
70:
27:
144:
78:
84:
41:
35:
49:
92:
196:
267:{{ambox | text = This page contains a copy of the infobox ({{tl|chembox}}) taken from revid of page ] with values updated to verified values.}}
228:
16:
235:
217:
166:
859:
Formula=C<sub>10</sub>H<sub>7</sub>N<sub>3</sub>O<sub>4</sub>S
173:
206:
79:
210:
155:
872:
C<sub>10</sub>H<sub>7</sub>N<sub>3</sub>O<sub>4</sub>S
224:
50:
789:
773:
741:
711:
592:
567:
537:
510:
414:
370:
177:
477:
444:
388:
353:
332:
302:
36:
632:| InChI = 1/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15)
625:| InChI = 1/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15)
93:
8:
162:
119:
192:
191:
Saving copy of the {{chembox}} taken from revid 418308349 of page
104:
103:
600:| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
692:| CASNo = <!-- blanked - oldvalue: 173903-47-4 -->
548:
ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
656:| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
649:| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
126:
672:| StdInChIKey = FDTZUTSGGSRHQF-UHFFFAOYSA-N
665:| StdInChIKey = FDTZUTSGGSRHQF-UHFFFAOYSA-N
207:Latest revision as of 22:55, 27 April 2021
797:| SMILES = O=C(Nc1ncc(s1)()=O)c2ccccc2O
10:
795:
779:
747:
717:
598:
573:
543:
516:
483:
450:
752:SMILES = O=C(Nc1ncc(s1)()=O)c2ccccc2O
683:| CASNo_Ref = {{cascite|correct|CAS}}
531:| OtherNames = Desacetyl-nitazoxanide
420:
394:
376:
359:
338:
308:
145:Revision as of 13:39, 10 January 2012
69:
26:
735:| UNII_Ref = {{fdacite|correct|FDA}}
135:
118:
247:
216:
204:
189:
154:
142:
14:
107:
1279:
87:
73:
44:
30:
518:|Section1={{Chembox Identifiers
197:Chem/Drugbox validation project
831:|Section2={{Chembox Properties
9:
1:
1264:
1255:
1244:
1233:
1222:
1213:
1202:
1191:
1182:
1171:
1162:
1119:
1106:
1097:
1084:
1075:
1062:
1044:
1037:
1030:
1003:
990:
981:
968:
959:
946:
937:
924:
915:
902:
887:
877:
862:
852:
834:
827:
820:
761:
731:
701:
688:
679:
557:
527:
463:
322:
292:
263:
199:(updated: 'CASNo').
7:
1041:|Section3={{Chembox Hazards
1284:
296:| Verifiedfields = changed
11:(Difference between pages)
1268:{{Organic-compound-stub}}
1262:
1253:
1242:
1231:
1220:
1211:
1200:
1189:
1180:
1169:
1160:
1117:
1113:
1095:
1091:
1073:
1069:
1028:
1001:
997:
979:
975:
957:
953:
935:
931:
913:
909:
818:
786:
770:
759:
755:
729:
725:
699:
695:
677:
640:
637:
589:
564:
555:
551:
525:
521:
474:
470:
441:
437:
385:
381:
350:
346:
326:| Watchedfields = changed
320:
316:
290:
270:
258:
255:
203:
141:
236:Extended confirmed users
616:| ChemSpiderID = 349588
609:| ChemSpiderID = 349588
140:
884:MolarMass=265.25 g/mol
340:|ImageFile=Tizoxanide.
584:{{Chembox Identifiers
847:{{Chembox Properties
174:Edit filter managers
101:
58:
765:| UNII = 15KFG88UOJ
705:| CASNo=173903-47-4
61:
18:
1123:| AutoignitionPt =
430:-''N''-(5-nitro-2-
361:| verifiedrevid =
310:| verifiedrevid =
249:correct IUPAC name
214:
152:
66:
23:
1272:
1057:{{Chembox Hazards
205:
143:
89:
75:
62:
46:
32:
19:
1275:
1110:| Autoignition=
781:| PubChem=394397
250:
242:
232:
213:
200:
184:
170:
151:
132:
131:
129:
124:
122:
114:
111:
105:
90:
76:
65:
47:
33:
22:
1283:
1282:
1278:
1277:
1276:
1274:
1273:
1269:
1258:
1249:
1238:
1227:
1216:
1207:
1196:
1185:
1176:
1165:
1156:
1149:
1140:
1133:
1124:
1111:
1102:
1089:
1080:
1079:| MainHazards =
1067:
1066:| MainHazards=
1058:
1056:
1053:
1050:
1042:
1033:
1024:
1017:
1008:
995:
986:
973:
964:
951:
942:
929:
920:
907:
898:
896:
893:
885:
883:
873:
871:
868:
860:
858:
848:
846:
843:
840:
832:
823:
814:
807:
798:
782:
766:
753:
751:
736:
723:
721:
706:
693:
684:
673:
666:
657:
650:
633:
626:
617:
610:
601:
585:
583:
580:
577:
560:
549:
547:
532:
519:
505:
503:
499:
496:-''N''-(5-nitro
495:
491:
488:
468:
459:
457:
454:
435:
433:
429:
425:
409:
408:
404:
401:
398:
379:
365:
364:
344:
343:
327:
314:
313:
297:
286:
279:
268:
251:
248:
246:
245:
244:
240:
238:
222:
220:
219:LegionMammal978
215:
209:
201:
190:
188:
187:
186:
182:
180:
160:
158:
153:
147:
139:
138:
137:
136:
134:
133:
127:
125:
120:
117:
115:
112:
110:Content deleted
109:
106:
102:
100:
99:
98:
97:
96:
95:
94:
86:
83:
82:
81:
80:
72:
63:
59:
57:
56:
55:
54:
53:
52:
51:
43:
40:
39:
38:
37:
29:
20:
13:
12:
5:
1281:
1271:
1270:
1267:
1265:
1263:
1260:
1259:
1256:
1254:
1251:
1250:
1247:
1245:
1243:
1240:
1239:
1236:
1234:
1232:
1229:
1228:
1225:
1223:
1221:
1218:
1217:
1214:
1212:
1209:
1208:
1205:
1203:
1201:
1198:
1197:
1195:==References==
1194:
1192:
1190:
1187:
1186:
1183:
1181:
1178:
1177:
1174:
1172:
1170:
1167:
1166:
1163:
1161:
1158:
1157:
1154:
1152:
1150:
1147:
1145:
1142:
1141:
1138:
1136:
1134:
1131:
1129:
1126:
1125:
1122:
1120:
1118:
1115:
1114:
1112:
1109:
1107:
1104:
1103:
1100:
1098:
1096:
1093:
1092:
1090:
1087:
1085:
1082:
1081:
1078:
1076:
1074:
1071:
1070:
1068:
1065:
1063:
1060:
1059:
1055:
1052:
1049:
1047:
1045:
1043:
1040:
1038:
1035:
1034:
1031:
1029:
1026:
1025:
1022:
1020:
1018:
1015:
1013:
1010:
1009:
1007:| Solubility =
1006:
1004:
1002:
999:
998:
996:
994:| Solubility=
993:
991:
988:
987:
984:
982:
980:
977:
976:
974:
971:
969:
966:
965:
962:
960:
958:
955:
954:
952:
949:
947:
944:
943:
940:
938:
936:
933:
932:
930:
927:
925:
922:
921:
919:| Appearance =
918:
916:
914:
911:
910:
908:
906:| Appearance=
905:
903:
900:
899:
895:
892:
890:
888:
886:
882:
880:
878:
875:
874:
870:
867:
865:
863:
861:
857:
855:
853:
850:
849:
845:
842:
839:
837:
835:
833:
830:
828:
825:
824:
821:
819:
816:
815:
812:
810:
808:
805:
803:
800:
799:
794:
792:
787:
784:
783:
778:
776:
771:
768:
767:
764:
762:
760:
757:
756:
754:
750:
746:
744:
738:
737:
734:
732:
730:
727:
726:
724:
722:PubChem=394397
720:
716:
714:
708:
707:
704:
702:
700:
697:
696:
694:
691:
689:
686:
685:
682:
680:
678:
675:
674:
671:
669:
667:
664:
662:
659:
658:
655:
653:
651:
648:
646:
643:
642:
639:
635:
634:
631:
629:
627:
624:
622:
619:
618:
615:
613:
611:
608:
606:
603:
602:
597:
595:
590:
587:
586:
582:
579:
576:
572:
570:
565:
562:
561:
558:
556:
553:
552:
550:
546:
542:
540:
534:
533:
530:
528:
526:
523:
522:
520:
515:
513:
507:
506:
501:
497:
493:
490:
486:
482:
480:
475:
472:
471:
469:
466:
464:
461:
460:
456:
453:
449:
447:
442:
439:
438:
436:
431:
427:
423:
419:
417:
411:
410:
406:
403:
400:
397:
393:
391:
386:
383:
382:
380:
375:
373:
367:
366:
362:
358:
356:
351:
348:
347:
345:
341:
337:
335:
329:
328:
325:
323:
321:
318:
317:
315:
311:
307:
305:
299:
298:
295:
293:
291:
288:
287:
284:
282:
280:
277:
275:
272:
271:
269:
266:
264:
261:
260:
257:
253:
252:
239:
234:
233:
218:
202:
181:
178:Administrators
172:
171:
156:
116:
108:
91:
85:
77:
71:
68:
67:
60:
48:
42:
34:
28:
25:
24:
17:
15:
6:
4:
3:
2:
1280:
1266:
1261:
1257:
1252:
1246:
1241:
1235:
1230:
1224:
1219:
1215:
1210:
1204:
1199:
1193:
1188:
1184:
1179:
1173:
1168:
1164:
1159:
1153:
1151:
1146:
1144:
1143:
1137:
1135:
1130:
1128:
1127:
1121:
1116:
1108:
1105:
1099:
1094:
1086:
1083:
1077:
1072:
1064:
1061:
1046:
1039:
1036:
1032:
1027:
1021:
1019:
1014:
1012:
1011:
1005:
1000:
992:
989:
985:| BoilingPt =
983:
978:
972:| BoilingPt=
970:
967:
963:| MeltingPt =
961:
956:
950:| MeltingPt=
948:
945:
939:
934:
926:
923:
917:
912:
904:
901:
889:
879:
876:
864:
854:
851:
836:
829:
826:
822:
817:
811:
809:
804:
802:
801:
796:
793:
791:
788:
785:
780:
777:
775:
772:
769:
763:
758:
748:
745:
743:
740:
739:
733:
728:
718:
715:
713:
710:
709:
703:
698:
690:
687:
681:
676:
670:
668:
663:
661:
660:
654:
652:
647:
645:
644:
636:
630:
628:
623:
621:
620:
614:
612:
607:
605:
604:
599:
596:
594:
591:
588:
574:
571:
569:
566:
563:
559:
554:
544:
541:
539:
536:
535:
529:
524:
517:
514:
512:
509:
508:
484:
481:
479:
476:
473:
465:
462:
451:
448:
446:
443:
440:
421:
418:
416:
413:
412:
395:
392:
390:
387:
384:
377:
374:
372:
369:
368:
360:
357:
355:
352:
349:
339:
336:
334:
331:
330:
324:
319:
309:
306:
304:
301:
300:
294:
289:
283:
281:
276:
274:
273:
265:
262:
254:
237:
230:
226:
221:
212:
208:
198:
194:
179:
175:
168:
164:
159:
150:
146:
130:
123:
113:Content added
897:265.25 g/mol
498:-1,3-thiazol
467:|OtherNames=
1206:{{reflist}}
1101:| FlashPt =
1088:| FlashPt=
941:| Density =
928:| Density=
891:| MolarMass
405:Tizoxanide.
378:|ImageSize=
504:)benzamide
434:)benzamide
193:Tizoxanide
88:Revision 2
45:Revision 1
866:| Formula
455:ImageSize
432:thiazolyl
424:IUPACName
399:ImageFile
363:470611156
312:418306988
285:{{chembox
278:{{chembox
1051:Section3
841:Section2
790:⚫
774:⚫
742:⚫
712:⚫
641:Line 19:
638:Line 17:
593:⚫
578:Section1
568:⚫
538:⚫
511:⚫
478:⚫
445:⚫
415:⚫
389:⚫
371:⚫
354:⚫
333:⚫
303:⚫
229:contribs
195:for the
167:contribs
157:Beetstra
128:Wikitext
494:Hydroxy
428:hydroxy
259:Line 1:
256:Line 1:
183:171,922
121:Visual
74:Page 2
64:Page 2
31:Page 1
21:Page 1
243:edits
241:7,893
185:edits
487:PIN
225:talk
211:edit
163:talk
149:edit
500:-2-
426:=2-
407:svg
342:png
1155:}}
1148:}}
1139:}}
1132:}}
1023:}}
1016:}}
813:}}
806:}}
502:yl
492:2-
227:|
176:,
165:|
1248:]
1237:]
1226:]
1054:=
1048:|
894:=
881:|
869:=
856:|
844:=
838:|
749:|
719:|
581:=
575:|
545:|
489:=
485:|
458:=
452:|
422:|
402:=
396:|
231:)
223:(
169:)
161:(
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.