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Tetracycline

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682: 659: 1147: 38: 47: 1194: 1286: 6158: 1537:. Tetracycline displayed higher potency, better solubility, and more favorable pharmacology than the other antibiotics in its class, leading to its FDA approval in 1954. The new compound was one of the first commercially successful semi-synthetic antibiotics that was used, and laid the foundation for the development of Sancycline, 1692:
to require tetracycline to develop beyond the larval stage. Modified males raised in a laboratory develop normally as they are supplied with this chemical and can be released into the wild. Their subsequent offspring inherit this trait, but find no tetracycline in their environments, so never develop
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models in mice. Engineers were able to develop a retrovirus that induced a particular type of leukemia in mice, and could then "switch" the cancer on and off through tetracycline administration. This could be used to grow the cancer in mice and then halt it at a particular stage to allow for further
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peptide chain. Tetracycline blocks the A-site so that a hydrogen bond is not formed between the amino acids. Tetracycline binds to the 30S and 50S subunit of microbial ribosomes. Thus, it prevents the formation of a peptide chain. The action is usually not inhibitory and irreversible even with the
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caused by bacterial infections. The mechanism of action for the antibacterial effect of tetracyclines relies on disrupting protein translation in bacteria, thereby damaging the ability of microbes to grow and repair; however, protein translation is also disrupted in eukaryotic
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withdrawal of the drug. Mammalian cells are not vulnerable to the effect of Tetracycline as these cells contain no 30S ribosomal subunits so do not accumulate the drug. This accounts for the relatively small off-site effect of tetracycline on human cells.
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Litch JM, Encarnacion M, Chen S, Leonard J, Burkoth TL (November 1996). "Use of the polymeric matrix as internal standard for quantitation of in vivo delivery of tetracycline HCl from Actisite tetracycline fiber during periodontal treatment".
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described the "big price hikes of some generic drugs" as a "relatively new phenomenon" which has left most pharmacists "grappling" with large upswings" in the "costs of generics, with 'overnight' price changes sometimes exceeding 1,000%."
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Discolor permanent teeth (yellow-gray-brown), from prenatal period through childhood and adulthood. Children receiving long- or short-term therapy with a tetracycline or glycylcycline may develop permanent brown discoloration of the
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in humans. Tetracycline labeling is used to determine the amount of bone growth within a certain period of time, usually a period around 21 days. Tetracycline is incorporated into mineralizing bone and can be detected by its
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Dugray A, Geay JF, Foudi A, Bonnet ML, Vainchenker W, Wendling F, et al. (October 2001). "Rapid generation of a tetracycline-inducible BCR-ABL defective retrovirus using a single autoregulatory retroviral cassette".
3285: 969:, and several other previously sensitive organisms is now quite common. Tetracyclines remain especially useful in the management of infections by certain obligately intracellular bacterial pathogens such as 2809: 793:
InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1
3278: 2333: 4076: 3271: 1633:. In the game, players may find the antibiotic to treat the common cold, influenza, cholera and infected wounds, but does not portray any side effects associated with tetracycline. 5147: 1521:(Aureomycin), in 1945. The structure of Aureomycin was elucidated in 1952 and published in 1954 by the Pfizer-Woodward group. After the discovery of the structure, researchers at 6092: 1488:
or a ribosomal protection protein. Efflux pumps actively eject tetracycline from the cell, preventing the build up of an inhibitory concentration of tetracycline in the
1610:. The term "tetracycline" is also used to denote the four-ring system of this compound; "tetracyclines" are related substances that contain the same four-ring system. 886: 5368: 5358: 2958: 5183: 912:
Tetracyclines have a broad spectrum of antibiotic action. Originally, they possessed some level of bacteriostatic activity against almost all medically relevant
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It is marketed under the brand names Sumycin, Tetracyn, and Panmycin, among others. Actisite is a thread-like fiber formulation used in dental applications.
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Bassett EJ, Keith MS, Armelagos GJ, Martin DL, Villanueva AR (September 1980). "Tetracycline-labeled human bone from ancient Sudanese Nubia (A.D. 350)".
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mummies from between 350 and 550 A.D. were found to exhibit patterns of fluorescence identical with that of modern tetracycline labelled bone.
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Sánchez AR, Rogers RS, Sheridan PJ (October 2004). "Tetracycline and other tetracycline-derivative staining of the teeth and oral cavity".
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Lippincott's Illustrated Reviews: Pharmacology, 4th ed. Harvery RA, Champe, PC. Lippincott, Williams & Wilkins, 2009
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Due to the drug's association with fighting infections, it serves as the main "commodity" in the science fiction series
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Armelagos G (2000). "Take Two Beers and Call Me in 1,600 Years: Use of Tetracycline by Nubians and Ancient Egyptians".
2076: 6218: 2450:"Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance" 1876: 941:, which display intrinsic resistance. However, acquired (as opposed to inherent) resistance has proliferated in many 785: 1244: 1223: 5167: 4889: 4037: 2883: 1069: 5942: 1933:"Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research" 6183: 3263: 421: 346: 166: 2366: 2100:"Bait ingestion by free-ranging raccoons and nontarget species in an oral rabies vaccine field trial in Florida" 1553:
Tetracycline has a high affinity for calcium and is incorporated into bones during the active mineralization of
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It is conjectured that the beer brewed by the Nubians was the source of the tetracycline found in these bones.
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Stephens CR, Conover LH, Pasternack R, Hochstein FA, Moreland WT, Regna PP, et al. (July 1954).
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There is evidence that early inhabitants of Northeastern Africa consumed tetracycline antibiotics.
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and greatly eroded the formerly vast versatility of this group of antibiotics. Resistance amongst
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reaction replaced a chlorine moiety with a hydrogen, creating a compound named tetracycline via
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It is also used to produce several semisynthetic derivatives, which together are known as the
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Tetracycline was patented in 1953 and was approved for prescription use in 1954. It is on the
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in 1948 as natural products, and first prescribed in 1948. Benjamin Duggar, working under
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Moullan N, Mouchiroud L, Wang X, Ryu D, Williams EG, Mottis A, et al. (March 2015).
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Caution should be exercised in long-term use when breastfeeding. Short-term use is safe;
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began chemically modifying aureomycin by treating it with hydrogen in the presence of a
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Since tetracycline is absorbed into bone, it is used as a marker of bone growth for
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Pautke C, Vogt S, Kreutzer K, Haczek C, Wexel G, Kolk A, et al. (July 2010).
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This article is about the specific antibiotic. For the family of antibiotics, see
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Chatzispyrou IA, Held NM, Mouchiroud L, Auwerx J, Houtkooper RH (November 2015).
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Conover LH, Moreland WT, English AR, Stephens CR, Pilgrim FJ (September 1953).
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Tetracycline inhibits protein synthesis by blocking the attachment of charged
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It is also one of a group of antibiotics which together may be used to treat
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World Health Organization model list of essential medicines: 21st list 2019
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may harm the baby. It works by inhibiting protein synthesis in bacteria.
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LiverTox: Clinical and Research Information on Drug-Induced Liver Injury
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Nelson ML, Levy SB (December 2011). "The history of the tetracyclines".
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remedies (some common antacids and over-the-counter heartburn medicines)
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use have been reported, but a causative role has not been established.
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if you can. Unsourced or poorly sourced material may be challenged and
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The tetracyclines, a large family of antibiotics, were discovered by
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Tetracycline hydrochloride is available as yellow crystalline powder.
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susceptibility data for some medically significant microorganisms:
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Antibiotics Manual : A Guide to Commonly Used Antimicrobials
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Jukes TH (1985). "Some historical notes on chlortetracycline".
1522: 1316: 1119: 893:. Tetracycline was originally made from bacteria of the genus 590: 2654: 2497:
Connell SR, Tracz DM, Nierhaus KH, Taylor DE (December 2003).
2419:"Antimicrobial Agents in the Treatment of Infectious Disease." 2037:
Susceptibility and Minimum Inhibitory Concentration (MIC) Data
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development if used by children less than eight years of age,
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C1(c2cccc(c2C(=O)C3=C(4((C31)(C(=C(C4=O)C(=O)N)O)N(C)C)O)O)O)O
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parasites, including those responsible for diseases such as
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According to data from EvaluatePharma and published in the
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Bacteria usually acquire resistance to tetracycline from
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by displacing it from the various protein-binding sites
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World Health Organization's List of Essential Medicines
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The tetracyclines also have activity against certain
103: 94: 88: 67: 2951:"Can GM mosquitoes rid the world of a major killer?" 1688:, and several other diseases) uses a strain that is 97: 79: 76: 70: 2798: 2097: 1662:A technique being developed for the control of the 85: 2548:"Chemistry and chemical biology of tetracyclines" 2302: 2098:Olson CA, Mitchell KD, Werner PA (October 2000). 831:family of medications, used to treat a number of 6170: 2290:Harvard Health Publishing Harvard Medical School 1517:, discovered the first tetracycline antibiotic, 1418:may result from ingesting expired tetracyclines. 478: 2227:. Treasure Island (FL): StatPearls Publishing. 1864: 999:. Certain rare or exotic infections, including 453: 446: 16:Antibiotic used to treat a number of infections 3652: 2317: 2218: 1218:Please review the contents of the section and 6224:World Health Organization essential medicines 5141: 4922: 4070: 3638: 3279: 2992: 2460:(2): 232–60, second page, table of contents. 2447: 2322:. Jones & Bartlett Learning. p. 179. 1742:National Center for Biotechnology Information 1426:in milk is low to nil. According to the U.S. 823:, sold under various brand names, is an oral 2318:Riordan J, Wambach K, eds. (November 2010). 2150:"Tetracycline: MedlinePlus Drug Information" 1973: 1166:Tetracycline is also used as a biomarker in 398:8–11 hours, 57–108 hours (kidney impairment) 184: 5424: 1924: 1590:pill in 2013 to $ 4.06 a pill in 2015. The 1471: 354:In general: ℞ (Prescription only) 328: 318: 308: 5475:Allopregnanedione (5α-dihydroprogesterone) 5148: 5134: 4929: 4915: 4538: 4077: 4063: 3645: 3631: 3286: 3272: 2999: 2985: 2454:Microbiology and Molecular Biology Reviews 2039:. TOKU-E. 8 September 2015. Archived from 1816:Annals of the New York Academy of Sciences 1813: 1767: 1765: 1763: 1761: 1759: 1757: 1755: 1753: 1751: 1398:Cause breathing complications, as well as 1338:ions, not to be taken at the same time as 680: 657: 518: 45: 36: 2807: 2785: 2719: 2522: 2473: 2005: 1956: 1809: 1807: 538: 5173:Tooltip Constitutive androstane receptor 2948: 2661:Journal of the American Chemical Society 2622:Journal of the American Chemical Society 2326: 1548: 1145: 2423:Todars Online Text Book of Bacteriology 1748: 907: 653: 498: 157: 6171: 5928:Pregnanedione (5β-dihydroprogesterone) 5314:Pregnanedione (5β-dihydroprogesterone) 3977:Clindamycin/adapalene/benzoyl peroxide 2367:"Mechanism of Action of Tetracyclines" 2081:The Johns Hopkins Medical Institutions 2050: 1889: 1885:from the original on 20 December 2016. 1871:. John Wiley & Sons. p. 489. 1804: 1641: 1570: 1454: 1170:to detect consumption of medicine- or 862:Common side effects include vomiting, 671: 5129: 4910: 4058: 3626: 3267: 2980: 2820:from the original on 19 November 2015 2572: 2503:Antimicrobial Agents and Chemotherapy 2416: 2364: 2334:"FDA Adverse Events Reporting System" 2214: 2212: 2210: 1903:. Geneva: World Health Organization. 1779:from the original on 28 December 2016 1141: 1105: 619: 598: 578: 175: 143: 2961:from the original on 5 December 2013 2181:International Journal of Dermatology 1625:Tetracycline is also represented in 1187: 625: 298: 288: 278: 268: 258: 248: 2429:from the original on 8 October 2013 558: 469: 13: 2854:10.1111/j.1600-0765.1996.tb00518.x 2207: 2056: 1098: 14: 6235: 2545: 2448:Chopra I, Roberts M (June 2001). 2320:Breastfeeding and Human Lactation 2303:Schlossberg DL, Samuel R (2017). 1087: 1083: 928:, with a few exceptions, such as 889:. Tetracycline is available as a 207: 6156: 2808:McCluskey PD (6 November 2015). 2712:10.1111/j.1469-7580.2010.01237.x 2515:10.1128/AAC.47.12.3675-3681.2003 2373:from the original on 5 June 2012 2342:. 27 August 2010. Archived from 2193:10.1111/j.1365-4632.2004.02108.x 2160:from the original on 10 May 2017 2083:. 8 January 2001. Archived from 1836:10.1111/j.1749-6632.2011.06354.x 1284: 1192: 711: 705: 63: 4937:Drugs used for diseases of the 2942: 2898: 2868: 2842:Journal of Periodontal Research 2832: 2779: 2736: 2687: 2648: 2618:"The Structure of Aureomycin 1" 2609: 2566: 2539: 2490: 2441: 2410: 2385: 2358: 2311: 2296: 2278: 2246: 2172: 2142: 2091: 2069: 2059:"Tetracycline labeling of bone" 2022: 1865:Fischer J, Ganellin CR (2006). 1711:"Antibiotic abbreviations list" 1449: 1177: 902: 798:Key:OFVLGDICTFRJMM-WESIUVDSSA-N 5480:Allopregnanolone (brexanolone) 4578:transpeptidation/translocation 2657:"Terramycin. Xi. Tetracycline" 2575:Reviews of Infectious Diseases 2466:10.1128/MMBR.65.2.232-260.2001 2219:Shutter MC, Akhondi H (2024). 1915: 1858: 1791: 1724: 1703: 1598: 1409:, so should be avoided during 1311:, so are not to be taken with 1220:add the appropriate references 717: 699: 1: 6135:Receptor/signaling modulators 6093:Tropanyl 3,5-dimethulbenzoate 5943:Pregnenolone 16α-carbonitrile 3992:Erythromycin/benzoyl peroxide 1998:10.1158/0008-5472.CAN-15-1626 1868:Analogue-based Drug Discovery 1696: 3982:Clindamycin/benzoyl peroxide 2339:Food and Drug Administration 2104:Journal of Wildlife Diseases 2030:"Tetracycline hydrochloride" 1949:10.1016/j.celrep.2015.02.034 1656:chronic myelogenous leukemia 1575: 1500: 1428:Food and Drug Administration 1068:The following list presents 1061:leading to effects that may 1013:Rocky Mountain spotted fever 987:. They are also of value in 965:, anaerobes, members of the 7: 5670:Dodecylbenzenesulfonic acid 5429:Tooltip Pregnane X receptor 5157:Xenobiotic-sensing receptor 2949:Urquhart C (15 July 2012). 1636: 1205:reliable medical references 10: 6240: 4007:Tretinoin/benzoyl peroxide 3972:Adapalene/benzoyl peroxide 3047:Sodium monofluorophosphate 2116:10.7589/0090-3558-36.4.734 1659:experimentation or study. 1652:transcriptional activation 1650:, tetracycline is used in 1527:palladized carbon catalyst 1495: 1436:toxic epidermal necrolysis 1405:Affect bone growth of the 1307:Be inactivated by calcium 1181: 689:Chemical and physical data 18: 6126: 5422: 5166: 5091: 5053: 4950: 4867: 4822:Quinupristin/dalfopristin 4780: 4752: 4724: 4586: 4575: 4529: 4475: 4466: 4440: 4354: 4339: 4319: 4258: 4141: 4126: 4117: 4090:inhibit protein synthesis 4015: 3997:Erythromycin/isotretinoin 3964: 3928: 3885: 3822: 3769: 3736: 3703: 3665: 3590: 3512: 3469: 3460: 3357: 3323: 3314: 3221: 3187: 3060: 3019: 2876:"Aftermath Episode Recap" 1897:World Health Organization 1211:or relies too heavily on 806: 781: 761: 739: 726: 693: 688: 669: 637: 609: 589: 569: 549: 529: 509: 489: 464: 437: 417: 412: 402: 389: 379: 369: 361: 345: 340: 235: 221: 195: 165: 151: 133: 125: 115: 58: 53: 44: 35: 6219:Tetracycline antibiotics 6053:Testosterone isocaproate 5968:Reverse triiodothyronine 4341:Tetracycline antibiotics 3099:Cetylpyridinium chloride 1613: 1608:tetracycline antibiotics 1472:Mechanisms of resistance 1432:Stevens–Johnson syndrome 1297:tetracycline antibiotics 1045:, and nasal carriage of 21:Tetracycline antibiotics 5445:17α-Hydroxyprogesterone 5440:17α-Hydroxypregnenolone 4965:Aluminium acetotartrate 2765:10.1126/science.7001623 2587:10.1093/clinids/7.5.702 2365:Mehta A (27 May 2011). 2077:"Tetracycline Labeling" 1484:that either encodes an 920:bacterial genera, both 6184:Anti-acne preparations 5073:Fluocinolone acetonide 2920:10.1038/sj.leu.2402225 2369:. Pharmaxchange.info. 1151: 1101:: 1 μg/mL to 128 μg/mL 1065:experimental results. 931:Pseudomonas aeruginosa 408:Urine (>60%), feces 5184:6,7-Dimethylesculetin 3987:Clindamycin/tretinoin 1629:'s survival sandbox, 1549:Evidence in antiquity 1511:Yellapragada Subbarow 1507:Benjamin Minge Duggar 1402:, in some individuals 1373:Cause microvesicular 1352:, so exposure to the 1149: 1042:Mycoplasma pneumoniae 962:Neisseria gonorrhoeae 5771:Hypericum perforatum 5760:Hetacillin potassium 4970:Aluminium triacetate 4531:Peptidyl transferase 4002:Sulfacetamide/sulfur 3234:Acetylsalicylic acid 3079:Benzoxonium chloride 2087:on 15 December 2012. 2046:on 8 September 2015. 1799:U.S. patent 2699054A 1690:genetically modified 1515:Lederle Laboratories 991:infections, such as 943:pathogenic organisms 908:Spectrum of activity 5600:Cyproterone acetate 5500:Amlodipine besylate 4160:Dihydrostreptomycin 3842:Cyproterone acetate 3479:Silver sulfadiazine 2757:1980Sci...209.1532B 2751:(4464): 1532–1534. 2673:10.1021/ja01114a537 2634:10.1021/ja01642a064 2393:"Tetracycline, USP" 1828:2011NYASA1241...17N 1648:genetic engineering 1642:Genetic engineering 1627:Bohemia Interactive 1571:Society and culture 1478:horizontal transfer 1455:Mechanism of action 1440:erythema multiforme 1363:Cause drug-induced 1174:-containing baits. 878:easily. Use during 32: 6179:1948 introductions 6073:Thonzonium bromide 5828:Methylprednisolone 5629:prasterone sulfate 4894:Never to phase III 4042:Never to phase III 3690:Blue light therapy 3685:8-Hydroxyquinoline 3656:-treating agents ( 2886:on 13 October 2017 2700:Journal of Anatomy 2346:on 17 January 2011 1400:anaphylactic shock 1360:is not recommended 1326:Be inactivated by 1152: 1142:Use as a biomarker 1106:Anti-eukaryote use 967:Enterobacteriaceae 891:generic medication 28: 6144: 6143: 5778:Indinavir sulfate 5485:Alpha-Lipoic acid 5460:Δ-Androstenedione 5450:Δ-Androstenedione 5123: 5122: 5010:Hydrogen peroxide 4904: 4903: 4863: 4862: 4859: 4858: 4571: 4570: 4462: 4461: 4458: 4457: 4367:Chlortetracycline 4335: 4334: 4052: 4051: 3761:Red light therapy 3738:Anti-inflammatory 3620: 3619: 3616: 3615: 3462:Chemotherapeutics 3456: 3455: 3339:Chlortetracycline 3299:chemotherapeutics 3261: 3260: 3179:Tibezonium iodide 3124:Hydrogen peroxide 3089:Chlortetracycline 3052:Stannous fluoride 2914:(10): 1658–1662. 2667:(18): 4622–4623. 2628:(13): 3568–3575. 2509:(12): 3675–3681. 2292:. 15 August 2022. 2138:on 15 April 2013. 2065:on 12 March 2007. 1992:(21): 4446–4449. 1943:(10): 1681–1691. 1519:chlortetracycline 1430:(FDA), cases of 1293: 1292: 1269: 818: 817: 752:Interactive image 639:CompTox Dashboard 211: 178: 6231: 6161: 6160: 6159: 6152: 6063:Thiamylal sodium 5798:γ-linolenic acid 5794:α-Linolenic acid 5792:Linolenic acid: 5783:Lasalocid sodium 5773:(St John's wort) 5665:Docusate calcium 5595:Cyclophosphamide 5470:Allopregnanediol 5455:Δ-Androstenediol 5430: 5426: 5384:Ethinylestradiol 5234:Cyclophosphamide 5174: 5170: 5150: 5143: 5136: 5127: 5126: 4974:Burow's solution 4931: 4924: 4917: 4908: 4907: 4584: 4583: 4536: 4535: 4473: 4472: 4422:Rolitetracycline 4352: 4351: 4139: 4138: 4124: 4123: 4079: 4072: 4065: 4056: 4055: 3875:Ethinylestradiol 3728:Benzoyl peroxide 3680:Benzoyl peroxide 3647: 3640: 3633: 3624: 3623: 3598:Ingenol mebutate 3467: 3466: 3321: 3320: 3288: 3281: 3274: 3265: 3264: 3169:Sodium perborate 3104:Domiphen bromide 3001: 2994: 2987: 2978: 2977: 2971: 2970: 2968: 2966: 2946: 2940: 2939: 2902: 2896: 2895: 2893: 2891: 2882:. Archived from 2872: 2866: 2865: 2836: 2830: 2829: 2827: 2825: 2805: 2796: 2795: 2783: 2777: 2776: 2740: 2734: 2733: 2723: 2691: 2685: 2684: 2652: 2646: 2645: 2613: 2607: 2606: 2570: 2564: 2563: 2561: 2559: 2550:. Archived from 2543: 2537: 2536: 2526: 2494: 2488: 2487: 2477: 2445: 2439: 2438: 2436: 2434: 2417:Todar K (2012). 2414: 2408: 2407: 2405: 2403: 2389: 2383: 2382: 2380: 2378: 2362: 2356: 2355: 2353: 2351: 2330: 2324: 2323: 2315: 2309: 2308: 2300: 2294: 2293: 2282: 2276: 2275: 2274: 2272: 2254:"Demeclocycline" 2250: 2244: 2243: 2241: 2239: 2216: 2205: 2204: 2176: 2170: 2169: 2167: 2165: 2146: 2140: 2139: 2134:. Archived from 2095: 2089: 2088: 2073: 2067: 2066: 2061:. Archived from 2054: 2048: 2047: 2045: 2034: 2026: 2020: 2019: 2009: 1977: 1971: 1970: 1960: 1928: 1922: 1919: 1913: 1912: 1893: 1887: 1886: 1862: 1856: 1855: 1811: 1802: 1801: 1795: 1789: 1788: 1786: 1784: 1769: 1746: 1745: 1728: 1722: 1721: 1719: 1717: 1707: 1541:, and later the 1442:associated with 1416:Fanconi syndrome 1350:photosensitivity 1288: 1287: 1279: 1276: 1270: 1268: 1227: 1196: 1195: 1188: 1100: 1090:to >128 μg/mL 1089: 1085: 1078:Escherichia coli 814: 813: 754: 734: 719: 713: 707: 701: 684: 673: 662: 661: 647: 645: 629: 623: 602: 582: 562: 542: 522: 502: 482: 472: 471: 457: 450: 394: 332: 322: 312: 302: 292: 282: 272: 262: 252: 209: 206: 188: 177: 174: 161: 147: 110: 109: 106: 105: 102: 99: 96: 93: 90: 87: 84: 81: 78: 75: 72: 69: 49: 40: 33: 31: 27: 6239: 6238: 6234: 6233: 6232: 6230: 6229: 6228: 6194:Cancer research 6169: 6168: 6167: 6157: 6155: 6147: 6145: 6140: 6122: 6023:Suberoylanilide 5740:Fluorometholone 5635:Dibunate sodium 5515:Aurothioglucose 5428: 5418: 5354:3,17β-Estradiol 5172: 5162: 5154: 5124: 5119: 5087: 5055:Corticosteroids 5049: 4985:Chloramphenicol 4946: 4935: 4905: 4900: 4899: 4884:Clinical trials 4855: 4841:Streptogramin B 4836:Streptogramin A 4776: 4748: 4720: 4567: 4548:Chloramphenicol 4525: 4479: 4454: 4436: 4417:Penimepicycline 4412:Oxytetracycline 4343: 4331: 4315: 4254: 4130: 4128:Aminoglycosides 4113: 4083: 4053: 4048: 4047: 4032:Clinical trials 4011: 3960: 3924: 3881: 3818: 3765: 3732: 3699: 3661: 3651: 3621: 3612: 3586: 3552:Podophyllotoxin 3508: 3452: 3376:Aminoglycosides 3369:Chloramphenicol 3353: 3344:Oxytetracycline 3327:and derivatives 3310: 3292: 3262: 3257: 3217: 3194:Glucocorticoids 3191: 3189:Corticosteroids 3183: 3056: 3042:Sodium fluoride 3015: 3005: 2975: 2974: 2964: 2962: 2947: 2943: 2903: 2899: 2889: 2887: 2874: 2873: 2869: 2837: 2833: 2823: 2821: 2806: 2799: 2788:Natural History 2784: 2780: 2741: 2737: 2692: 2688: 2653: 2649: 2614: 2610: 2571: 2567: 2557: 2555: 2554:on 17 June 2007 2544: 2540: 2495: 2491: 2446: 2442: 2432: 2430: 2415: 2411: 2401: 2399: 2391: 2390: 2386: 2376: 2374: 2363: 2359: 2349: 2347: 2332: 2331: 2327: 2316: 2312: 2301: 2297: 2284: 2283: 2279: 2270: 2268: 2252: 2251: 2247: 2237: 2235: 2217: 2208: 2187:(10): 709–715. 2177: 2173: 2163: 2161: 2154:medlineplus.gov 2148: 2147: 2143: 2096: 2092: 2075: 2074: 2070: 2055: 2051: 2043: 2032: 2028: 2027: 2023: 1986:Cancer Research 1978: 1974: 1929: 1925: 1920: 1916: 1894: 1890: 1879: 1863: 1859: 1812: 1805: 1797: 1796: 1792: 1782: 1780: 1771: 1770: 1749: 1730: 1729: 1725: 1715: 1713: 1709: 1708: 1704: 1699: 1672:(the infection 1644: 1639: 1616: 1601: 1578: 1573: 1551: 1503: 1498: 1474: 1457: 1452: 1424:bioavailability 1391:Interfere with 1387:epigastric pain 1289: 1285: 1280: 1274: 1271: 1228: 1217: 1213:primary sources 1197: 1193: 1186: 1184:Tooth bleaching 1180: 1144: 1108: 910: 905: 872:kidney problems 809: 807: 802: 799: 794: 789: 788: 777: 774: 769: 768: 757: 732: 722: 716: 710: 704: 665: 641: 633: 605: 585: 565: 545: 525: 505: 485: 468: 460: 433: 430: 425: 424: 392: 385:Not metabolized 371:Bioavailability 363:Pharmacokinetic 357: 336: 224: 217: 198: 191: 66: 62: 24: 17: 12: 11: 5: 6237: 6227: 6226: 6221: 6216: 6211: 6206: 6201: 6196: 6191: 6186: 6181: 6166: 6165: 6142: 6141: 6139: 6138: 6131: 6127: 6124: 6123: 6121: 6120: 6115: 6106: 6105: 6100: 6095: 6090: 6088:Troleandomycin 6085: 6080: 6075: 6070: 6065: 6060: 6055: 6050: 6045: 6040: 6035: 6030: 6025: 6020: 6015: 6010: 6008:Spironolactone 6005: 6000: 5995: 5990: 5985: 5980: 5975: 5970: 5965: 5960: 5955: 5950: 5945: 5940: 5935: 5930: 5925: 5920: 5915: 5910: 5905: 5900: 5895: 5890: 5885: 5880: 5878:Norelgestromin 5875: 5870: 5865: 5860: 5855: 5850: 5845: 5840: 5835: 5830: 5825: 5820: 5815: 5810: 5805: 5800: 5790: 5785: 5780: 5775: 5767: 5762: 5757: 5752: 5747: 5742: 5737: 5735:Flucloxacillin 5732: 5727: 5722: 5717: 5712: 5707: 5702: 5697: 5692: 5687: 5682: 5677: 5672: 5667: 5662: 5657: 5652: 5647: 5642: 5637: 5632: 5622: 5612: 5607: 5602: 5597: 5592: 5590:Corticosterone 5587: 5582: 5577: 5572: 5567: 5562: 5557: 5555:Chlorpromazine 5552: 5547: 5542: 5537: 5532: 5527: 5522: 5517: 5512: 5507: 5502: 5497: 5492: 5487: 5482: 5477: 5472: 5467: 5462: 5457: 5452: 5447: 5442: 5433: 5431: 5420: 5419: 5417: 5416: 5411: 5406: 5401: 5396: 5391: 5386: 5381: 5376: 5374:17-Androstanol 5371: 5369:3β-Androstanol 5366: 5364:3α-Androstenol 5361: 5359:3α-Androstanol 5356: 5347: 5346: 5341: 5336: 5331: 5326: 5321: 5316: 5311: 5306: 5301: 5296: 5291: 5286: 5281: 5276: 5271: 5266: 5261: 5256: 5251: 5241: 5236: 5231: 5226: 5221: 5216: 5214:Chlorpromazine 5211: 5206: 5201: 5196: 5191: 5186: 5177: 5175: 5164: 5163: 5153: 5152: 5145: 5138: 5130: 5121: 5120: 5118: 5117: 5112: 5107: 5101: 5099: 5089: 5088: 5086: 5085: 5080: 5078:Hydrocortisone 5075: 5070: 5065: 5059: 5057: 5051: 5050: 5048: 5047: 5042: 5037: 5032: 5027: 5022: 5017: 5012: 5007: 5002: 4997: 4992: 4987: 4982: 4977: 4967: 4962: 4956: 4954: 4948: 4947: 4934: 4933: 4926: 4919: 4911: 4902: 4901: 4898: 4897: 4896: 4895: 4892: 4881: 4875: 4869: 4868: 4865: 4864: 4861: 4860: 4857: 4856: 4854: 4853: 4843: 4838: 4833: 4819: 4805: 4786: 4784: 4782:Streptogramins 4778: 4777: 4775: 4774: 4769: 4764: 4758: 4756: 4750: 4749: 4747: 4746: 4741: 4736: 4730: 4728: 4722: 4721: 4719: 4718: 4713: 4708: 4703: 4701:Troleandomycin 4698: 4693: 4688: 4683: 4678: 4673: 4668: 4663: 4658: 4653: 4648: 4643: 4638: 4633: 4631:Flurithromycin 4628: 4623: 4618: 4616:Clarithromycin 4613: 4608: 4603: 4598: 4592: 4590: 4581: 4573: 4572: 4569: 4568: 4566: 4565: 4560: 4555: 4550: 4544: 4542: 4533: 4527: 4526: 4524: 4523: 4518: 4513: 4508: 4503: 4498: 4493: 4487: 4485: 4470: 4464: 4463: 4460: 4459: 4456: 4455: 4453: 4452: 4446: 4444: 4442:Glycylcyclines 4438: 4437: 4435: 4434: 4429: 4424: 4419: 4414: 4409: 4404: 4399: 4394: 4389: 4384: 4379: 4377:Demeclocycline 4374: 4369: 4364: 4358: 4356: 4349: 4337: 4336: 4333: 4332: 4330: 4329: 4323: 4321: 4317: 4316: 4314: 4313: 4308: 4302: 4301: 4300: 4299: 4294: 4289: 4284: 4279: 4268: 4266: 4262:Micromonospora 4256: 4255: 4253: 4252: 4250:Nourseothricin 4247: 4242: 4237: 4232: 4227: 4216: 4215: 4214: 4213: 4208: 4203: 4198: 4187: 4186: 4185: 4184: 4179: 4174: 4163: 4162: 4157: 4151: 4149: 4136: 4121: 4115: 4114: 4086:Antibacterials 4082: 4081: 4074: 4067: 4059: 4050: 4049: 4046: 4045: 4044: 4043: 4040: 4029: 4023: 4017: 4016: 4013: 4012: 4010: 4009: 4004: 3999: 3994: 3989: 3984: 3979: 3974: 3968: 3966: 3962: 3961: 3959: 3958: 3953: 3948: 3943: 3938: 3932: 3930: 3926: 3925: 3923: 3922: 3917: 3912: 3907: 3902: 3897: 3891: 3889: 3883: 3882: 3880: 3879: 3878: 3877: 3872: 3862: 3861: 3860: 3857:Spironolactone 3854: 3849: 3844: 3839: 3828: 3826: 3820: 3819: 3817: 3816: 3810: 3805: 3796: 3791: 3786: 3781: 3775: 3773: 3767: 3766: 3764: 3763: 3758: 3753: 3748: 3742: 3740: 3734: 3733: 3731: 3730: 3725: 3720: 3718:Salicylic acid 3715: 3709: 3707: 3701: 3700: 3698: 3697: 3692: 3687: 3682: 3677: 3671: 3669: 3663: 3662: 3650: 3649: 3642: 3635: 3627: 3618: 3617: 3614: 3613: 3611: 3610: 3605: 3600: 3594: 3592: 3588: 3587: 3585: 3584: 3579: 3574: 3569: 3564: 3559: 3554: 3549: 3544: 3539: 3534: 3529: 3524: 3518: 3516: 3510: 3509: 3507: 3506: 3501: 3496: 3494:Sulfamethizole 3491: 3486: 3481: 3475: 3473: 3464: 3458: 3457: 3454: 3453: 3451: 3450: 3445: 3440: 3435: 3426: 3425: 3415: 3414: 3404: 3403: 3393: 3392: 3387: 3382: 3372: 3371: 3361: 3359: 3355: 3354: 3352: 3351: 3346: 3341: 3336: 3334:Demeclocycline 3330: 3328: 3318: 3312: 3311: 3303:dermatological 3291: 3290: 3283: 3276: 3268: 3259: 3258: 3256: 3255: 3246: 3241: 3236: 3231: 3225: 3223: 3219: 3218: 3216: 3215: 3210: 3208:Hydrocortisone 3205: 3199: 3197: 3185: 3184: 3182: 3181: 3176: 3171: 3166: 3161: 3156: 3151: 3146: 3141: 3136: 3131: 3126: 3121: 3116: 3111: 3106: 3101: 3096: 3091: 3086: 3081: 3076: 3074:Amphotericin B 3070: 3068: 3058: 3057: 3055: 3054: 3049: 3044: 3039: 3034: 3028: 3026: 3017: 3016: 3010:preparations ( 3008:Stomatological 3004: 3003: 2996: 2989: 2981: 2973: 2972: 2941: 2897: 2867: 2848:(8): 540–544. 2831: 2797: 2778: 2735: 2686: 2647: 2608: 2581:(5): 702–707. 2565: 2538: 2489: 2440: 2409: 2384: 2357: 2325: 2310: 2295: 2277: 2245: 2221:"Tetracycline" 2206: 2171: 2141: 2110:(4): 734–743. 2090: 2068: 2049: 2021: 1972: 1923: 1914: 1888: 1877: 1857: 1803: 1790: 1773:"Tetracycline" 1747: 1732:"Tetracycline" 1723: 1701: 1700: 1698: 1695: 1643: 1640: 1638: 1635: 1615: 1612: 1600: 1597: 1577: 1574: 1572: 1569: 1555:hydroxyapatite 1550: 1547: 1543:Glycylcyclines 1535:hydrogenolysis 1502: 1499: 1497: 1494: 1473: 1470: 1456: 1453: 1451: 1448: 1420: 1419: 1413: 1403: 1396: 1389: 1383: 1377: 1371: 1361: 1343: 1324: 1305: 1291: 1290: 1283: 1281: 1234:"Tetracycline" 1200: 1198: 1191: 1179: 1176: 1143: 1140: 1107: 1104: 1103: 1102: 1091: 1025:B. burgdorferi 948:Staphylococcus 909: 906: 904: 901: 816: 815: 804: 803: 801: 800: 797: 795: 792: 784: 783: 782: 779: 778: 776: 775: 772: 764: 763: 762: 759: 758: 756: 755: 747: 745: 737: 736: 730: 724: 723: 720: 714: 708: 702: 697: 691: 690: 686: 685: 675: 667: 666: 664: 663: 650: 648: 635: 634: 632: 631: 615: 613: 607: 606: 604: 603: 595: 593: 587: 586: 584: 583: 575: 573: 567: 566: 564: 563: 555: 553: 547: 546: 544: 543: 535: 533: 527: 526: 524: 523: 515: 513: 507: 506: 504: 503: 495: 493: 487: 486: 484: 483: 475: 473: 462: 461: 459: 458: 451: 443: 441: 435: 434: 432: 431: 428: 420: 419: 418: 415: 414: 410: 409: 406: 400: 399: 396: 387: 386: 383: 377: 376: 373: 367: 366: 359: 358: 356: 355: 351: 349: 343: 342: 338: 337: 335: 334: 241: 239: 233: 232: 227: 225:administration 219: 218: 216: 215: 213: 203: 201: 193: 192: 190: 189: 171: 169: 163: 162: 155: 149: 148: 141: 131: 130: 127: 123: 122: 119: 113: 112: 60: 56: 55: 51: 50: 42: 41: 15: 9: 6: 4: 3: 2: 6236: 6225: 6222: 6220: 6217: 6215: 6212: 6210: 6207: 6205: 6202: 6200: 6197: 6195: 6192: 6190: 6187: 6185: 6182: 6180: 6177: 6176: 6174: 6164: 6154: 6153: 6150: 6137: 6136: 6132: 6129: 6128: 6125: 6119: 6116: 6114: 6111: 6108: 6107: 6104: 6101: 6099: 6096: 6094: 6091: 6089: 6086: 6084: 6081: 6079: 6076: 6074: 6071: 6069: 6066: 6064: 6061: 6059: 6056: 6054: 6051: 6049: 6046: 6044: 6041: 6039: 6036: 6034: 6031: 6029: 6028:Sulfisoxazole 6026: 6024: 6021: 6019: 6016: 6014: 6011: 6009: 6006: 6004: 6001: 5999: 5996: 5994: 5991: 5989: 5986: 5984: 5981: 5979: 5976: 5974: 5971: 5969: 5966: 5964: 5961: 5959: 5956: 5954: 5951: 5949: 5946: 5944: 5941: 5939: 5936: 5934: 5931: 5929: 5926: 5924: 5921: 5919: 5916: 5914: 5911: 5909: 5906: 5904: 5903:Phenobarbital 5901: 5899: 5896: 5894: 5891: 5889: 5886: 5884: 5881: 5879: 5876: 5874: 5871: 5869: 5866: 5864: 5861: 5859: 5856: 5854: 5851: 5849: 5846: 5844: 5841: 5839: 5836: 5834: 5831: 5829: 5826: 5824: 5821: 5819: 5816: 5814: 5811: 5809: 5806: 5804: 5801: 5799: 5795: 5791: 5789: 5788:Levothyroxine 5786: 5784: 5781: 5779: 5776: 5774: 5772: 5768: 5766: 5763: 5761: 5758: 5756: 5753: 5751: 5750:Guggulsterone 5748: 5746: 5743: 5741: 5738: 5736: 5733: 5731: 5728: 5726: 5723: 5721: 5718: 5716: 5713: 5711: 5708: 5706: 5703: 5701: 5698: 5696: 5693: 5691: 5688: 5686: 5683: 5681: 5678: 5676: 5673: 5671: 5668: 5666: 5663: 5661: 5658: 5656: 5653: 5651: 5648: 5646: 5645:Dicloxacillin 5643: 5641: 5638: 5636: 5633: 5630: 5626: 5623: 5620: 5616: 5613: 5611: 5610:Dexamethasone 5608: 5606: 5603: 5601: 5598: 5596: 5593: 5591: 5588: 5586: 5583: 5581: 5578: 5576: 5573: 5571: 5568: 5566: 5563: 5561: 5558: 5556: 5553: 5551: 5548: 5546: 5545:Cephaloridine 5543: 5541: 5538: 5536: 5533: 5531: 5528: 5526: 5523: 5521: 5518: 5516: 5513: 5511: 5508: 5506: 5503: 5501: 5498: 5496: 5493: 5491: 5488: 5486: 5483: 5481: 5478: 5476: 5473: 5471: 5468: 5466: 5463: 5461: 5458: 5456: 5453: 5451: 5448: 5446: 5443: 5441: 5438: 5435: 5434: 5432: 5427: 5421: 5415: 5412: 5410: 5407: 5405: 5402: 5400: 5397: 5395: 5392: 5390: 5387: 5385: 5382: 5380: 5377: 5375: 5372: 5370: 5367: 5365: 5362: 5360: 5357: 5355: 5352: 5349: 5348: 5345: 5344:Valproic acid 5342: 5340: 5337: 5335: 5332: 5330: 5327: 5325: 5322: 5320: 5317: 5315: 5312: 5310: 5307: 5305: 5304:Phenobarbital 5302: 5300: 5297: 5295: 5292: 5290: 5287: 5285: 5282: 5280: 5277: 5275: 5272: 5270: 5267: 5265: 5262: 5260: 5257: 5255: 5252: 5249: 5245: 5242: 5240: 5237: 5235: 5232: 5230: 5227: 5225: 5222: 5220: 5217: 5215: 5212: 5210: 5207: 5205: 5204:Carbamazepine 5202: 5200: 5197: 5195: 5192: 5190: 5187: 5185: 5182: 5179: 5178: 5176: 5171: 5165: 5161: 5158: 5151: 5146: 5144: 5139: 5137: 5132: 5131: 5128: 5116: 5113: 5111: 5108: 5106: 5103: 5102: 5100: 5098: 5094: 5090: 5084: 5081: 5079: 5076: 5074: 5071: 5069: 5068:Dexamethasone 5066: 5064: 5063:Betamethasone 5061: 5060: 5058: 5056: 5052: 5046: 5043: 5041: 5038: 5036: 5033: 5031: 5028: 5026: 5025:Nitrofurazone 5023: 5021: 5018: 5016: 5013: 5011: 5008: 5006: 5003: 5001: 4998: 4996: 4995:Ciprofloxacin 4993: 4991: 4990:Chlorhexidine 4988: 4986: 4983: 4981: 4978: 4975: 4971: 4968: 4966: 4963: 4961: 4958: 4957: 4955: 4953: 4949: 4944: 4940: 4932: 4927: 4925: 4920: 4918: 4913: 4912: 4909: 4893: 4891: 4888: 4887: 4885: 4882: 4879: 4876: 4874: 4871: 4870: 4866: 4851: 4847: 4846:Virginiamycin 4844: 4842: 4839: 4837: 4834: 4831: 4827: 4823: 4820: 4817: 4813: 4809: 4806: 4803: 4799: 4795: 4791: 4790:Pristinamycin 4788: 4787: 4785: 4783: 4779: 4773: 4770: 4768: 4765: 4763: 4760: 4759: 4757: 4755: 4751: 4745: 4744:Solithromycin 4742: 4740: 4737: 4735: 4734:Telithromycin 4732: 4731: 4729: 4727: 4723: 4717: 4714: 4712: 4709: 4707: 4706:Tulathromycin 4704: 4702: 4699: 4697: 4694: 4692: 4689: 4687: 4686:Telithromycin 4684: 4682: 4679: 4677: 4676:Solithromycin 4674: 4672: 4671:Roxithromycin 4669: 4667: 4664: 4662: 4659: 4657: 4654: 4652: 4649: 4647: 4644: 4642: 4639: 4637: 4636:Gamithromycin 4634: 4632: 4629: 4627: 4624: 4622: 4621:Dirithromycin 4619: 4617: 4614: 4612: 4609: 4607: 4604: 4602: 4599: 4597: 4594: 4593: 4591: 4589: 4585: 4582: 4579: 4574: 4564: 4561: 4559: 4558:Thiamphenicol 4556: 4554: 4553:Azidamfenicol 4551: 4549: 4546: 4545: 4543: 4541: 4537: 4534: 4532: 4528: 4522: 4519: 4517: 4514: 4512: 4509: 4507: 4504: 4502: 4499: 4497: 4494: 4492: 4489: 4488: 4486: 4483: 4478: 4477:Oxazolidinone 4474: 4471: 4469: 4465: 4451: 4448: 4447: 4445: 4443: 4439: 4433: 4430: 4428: 4425: 4423: 4420: 4418: 4415: 4413: 4410: 4408: 4405: 4403: 4400: 4398: 4395: 4393: 4390: 4388: 4385: 4383: 4380: 4378: 4375: 4373: 4370: 4368: 4365: 4363: 4360: 4359: 4357: 4355:Tetracyclines 4353: 4350: 4347: 4342: 4338: 4328: 4325: 4324: 4322: 4318: 4312: 4309: 4307: 4304: 4303: 4298: 4295: 4293: 4290: 4288: 4285: 4283: 4280: 4278: 4275: 4274: 4273: 4270: 4269: 4267: 4264: 4263: 4257: 4251: 4248: 4246: 4243: 4241: 4238: 4236: 4233: 4231: 4230:Spectinomycin 4228: 4225: 4221: 4218: 4217: 4212: 4209: 4207: 4204: 4202: 4199: 4197: 4194: 4193: 4192: 4189: 4188: 4183: 4180: 4178: 4175: 4173: 4170: 4169: 4168: 4165: 4164: 4161: 4158: 4156: 4153: 4152: 4150: 4147: 4146: 4140: 4137: 4134: 4129: 4125: 4122: 4120: 4116: 4111: 4107: 4103: 4099: 4095: 4091: 4087: 4080: 4075: 4073: 4068: 4066: 4061: 4060: 4057: 4041: 4039: 4036: 4035: 4033: 4030: 4027: 4024: 4022: 4019: 4018: 4014: 4008: 4005: 4003: 4000: 3998: 3995: 3993: 3990: 3988: 3985: 3983: 3980: 3978: 3975: 3973: 3970: 3969: 3967: 3963: 3957: 3954: 3952: 3949: 3947: 3944: 3942: 3939: 3937: 3934: 3933: 3931: 3927: 3921: 3918: 3916: 3913: 3911: 3908: 3906: 3903: 3901: 3898: 3896: 3893: 3892: 3890: 3888: 3884: 3876: 3873: 3871: 3868: 3867: 3866: 3863: 3858: 3855: 3853: 3850: 3848: 3845: 3843: 3840: 3838: 3835: 3834: 3833: 3832:Antiandrogens 3830: 3829: 3827: 3825: 3821: 3814: 3811: 3809: 3806: 3804: 3800: 3799:Tetracyclines 3797: 3795: 3794:Sulfacetamide 3792: 3790: 3787: 3785: 3782: 3780: 3777: 3776: 3774: 3772: 3768: 3762: 3759: 3757: 3754: 3752: 3749: 3747: 3744: 3743: 3741: 3739: 3735: 3729: 3726: 3724: 3721: 3719: 3716: 3714: 3713:Glycolic acid 3711: 3710: 3708: 3706: 3702: 3696: 3693: 3691: 3688: 3686: 3683: 3681: 3678: 3676: 3673: 3672: 3670: 3668: 3667:Antibacterial 3664: 3659: 3655: 3648: 3643: 3641: 3636: 3634: 3629: 3628: 3625: 3609: 3606: 3604: 3603:Metronidazole 3601: 3599: 3596: 3595: 3593: 3589: 3583: 3580: 3578: 3575: 3573: 3570: 3568: 3565: 3563: 3560: 3558: 3555: 3553: 3550: 3548: 3545: 3543: 3540: 3538: 3535: 3533: 3530: 3528: 3525: 3523: 3520: 3519: 3517: 3515: 3511: 3505: 3504:Sulfamerazine 3502: 3500: 3499:Sulfanilamide 3497: 3495: 3492: 3490: 3487: 3485: 3484:Sulfathiazole 3482: 3480: 3477: 3476: 3474: 3472: 3468: 3465: 3463: 3459: 3449: 3446: 3444: 3441: 3439: 3436: 3434: 3431: 3428: 3427: 3424: 3420: 3417: 3416: 3413: 3412:Virginiamycin 3409: 3408:Streptogramin 3406: 3405: 3402: 3398: 3395: 3394: 3391: 3388: 3386: 3383: 3381: 3377: 3374: 3373: 3370: 3366: 3363: 3362: 3360: 3356: 3350: 3347: 3345: 3342: 3340: 3337: 3335: 3332: 3331: 3329: 3326: 3322: 3319: 3317: 3313: 3308: 3304: 3300: 3296: 3289: 3284: 3282: 3277: 3275: 3270: 3269: 3266: 3254: 3250: 3247: 3245: 3242: 3240: 3237: 3235: 3232: 3230: 3227: 3226: 3224: 3220: 3214: 3213:Triamcinolone 3211: 3209: 3206: 3204: 3203:Dexamethasone 3201: 3200: 3198: 3195: 3190: 3186: 3180: 3177: 3175: 3172: 3170: 3167: 3165: 3162: 3160: 3157: 3155: 3152: 3150: 3147: 3145: 3142: 3140: 3137: 3135: 3134:Metronidazole 3132: 3130: 3127: 3125: 3122: 3120: 3117: 3115: 3112: 3110: 3107: 3105: 3102: 3100: 3097: 3095: 3092: 3090: 3087: 3085: 3084:Chlorhexidine 3082: 3080: 3077: 3075: 3072: 3071: 3069: 3067: 3063: 3059: 3053: 3050: 3048: 3045: 3043: 3040: 3038: 3035: 3033: 3030: 3029: 3027: 3025: 3022: 3018: 3013: 3009: 3002: 2997: 2995: 2990: 2988: 2983: 2982: 2979: 2960: 2956: 2952: 2945: 2937: 2933: 2929: 2925: 2921: 2917: 2913: 2909: 2901: 2885: 2881: 2877: 2871: 2863: 2859: 2855: 2851: 2847: 2843: 2835: 2819: 2815: 2811: 2804: 2802: 2793: 2789: 2782: 2774: 2770: 2766: 2762: 2758: 2754: 2750: 2746: 2739: 2731: 2727: 2722: 2717: 2713: 2709: 2705: 2701: 2697: 2690: 2682: 2678: 2674: 2670: 2666: 2662: 2658: 2651: 2643: 2639: 2635: 2631: 2627: 2623: 2619: 2612: 2604: 2600: 2596: 2592: 2588: 2584: 2580: 2576: 2569: 2553: 2549: 2542: 2534: 2530: 2525: 2520: 2516: 2512: 2508: 2504: 2500: 2493: 2485: 2481: 2476: 2471: 2467: 2463: 2459: 2455: 2451: 2444: 2428: 2424: 2420: 2413: 2398: 2394: 2388: 2372: 2368: 2361: 2345: 2341: 2340: 2335: 2329: 2321: 2314: 2306: 2299: 2291: 2287: 2281: 2267: 2263: 2259: 2255: 2249: 2234: 2230: 2226: 2222: 2215: 2213: 2211: 2202: 2198: 2194: 2190: 2186: 2182: 2175: 2159: 2155: 2151: 2145: 2137: 2133: 2129: 2125: 2121: 2117: 2113: 2109: 2105: 2101: 2094: 2086: 2082: 2078: 2072: 2064: 2060: 2053: 2042: 2038: 2031: 2025: 2017: 2013: 2008: 2003: 1999: 1995: 1991: 1987: 1983: 1976: 1968: 1964: 1959: 1954: 1950: 1946: 1942: 1938: 1934: 1927: 1918: 1910: 1906: 1902: 1898: 1892: 1884: 1880: 1878:9783527607495 1874: 1870: 1869: 1861: 1853: 1849: 1845: 1841: 1837: 1833: 1829: 1825: 1821: 1817: 1810: 1808: 1800: 1794: 1778: 1774: 1768: 1766: 1764: 1762: 1760: 1758: 1756: 1754: 1752: 1743: 1739: 1738: 1733: 1727: 1712: 1706: 1702: 1694: 1693:into adults. 1691: 1687: 1683: 1679: 1675: 1671: 1670: 1669:Aedes aegypti 1665: 1660: 1657: 1653: 1649: 1634: 1632: 1628: 1623: 1621: 1611: 1609: 1604: 1596: 1593: 1589: 1585: 1584: 1568: 1565: 1563: 1558: 1556: 1546: 1544: 1540: 1536: 1532: 1528: 1524: 1520: 1516: 1512: 1508: 1493: 1491: 1487: 1483: 1479: 1469: 1466: 1462: 1447: 1445: 1441: 1437: 1433: 1429: 1425: 1417: 1414: 1412: 1408: 1404: 1401: 1397: 1394: 1390: 1388: 1384: 1382: 1378: 1376: 1372: 1370: 1366: 1362: 1359: 1355: 1351: 1348: 1344: 1341: 1337: 1333: 1329: 1325: 1322: 1318: 1314: 1310: 1306: 1302: 1301: 1300: 1298: 1282: 1278: 1275:November 2022 1267: 1264: 1260: 1257: 1253: 1250: 1246: 1243: 1239: 1236: –  1235: 1231: 1230:Find sources: 1225: 1221: 1215: 1214: 1210: 1206: 1201:This section 1199: 1190: 1189: 1185: 1175: 1173: 1169: 1164: 1162: 1157: 1148: 1139: 1137: 1133: 1132:balantidiasis 1129: 1125: 1121: 1118:caused by an 1117: 1113: 1097: 1096: 1092: 1081: 1079: 1075: 1074: 1073: 1071: 1066: 1064: 1060: 1055: 1054:peptic ulcers 1050: 1048: 1044: 1043: 1038: 1034: 1030: 1026: 1022: 1018: 1014: 1010: 1006: 1002: 998: 994: 990: 986: 985: 980: 979: 974: 973: 968: 964: 963: 958: 956: 955:Streptococcus 951: 949: 944: 940: 938: 933: 932: 927: 926:Gram-negative 923: 922:Gram-positive 919: 915: 900: 898: 897: 892: 888: 883: 881: 877: 873: 869: 865: 860: 858: 854: 850: 846: 842: 838: 834: 830: 829:tetracyclines 826: 822: 812: 805: 796: 791: 790: 787: 780: 771: 770: 767: 760: 753: 749: 748: 746: 743: 738: 731: 729: 725: 698: 696: 692: 687: 683: 679: 676: 674: 672:ECHA InfoCard 668: 660: 656: 655:DTXSID7023645 652: 651: 649: 640: 636: 628: 627:RCSB PDB 622: 617: 616: 614: 612: 608: 601: 597: 596: 594: 592: 588: 581: 577: 576: 574: 572: 568: 561: 557: 556: 554: 552: 548: 541: 537: 536: 534: 532: 528: 521: 517: 516: 514: 512: 508: 501: 497: 496: 494: 492: 488: 481: 477: 476: 474: 467: 463: 456: 452: 449: 445: 444: 442: 440: 436: 427: 426: 423: 416: 411: 407: 405: 401: 397: 395: 388: 384: 382: 378: 374: 372: 368: 364: 360: 353: 352: 350: 348: 344: 339: 331: 326: 321: 316: 311: 306: 301: 296: 291: 286: 281: 276: 271: 266: 261: 256: 251: 246: 243: 242: 240: 238: 234: 231: 228: 226: 220: 214: 205: 204: 202: 200: 194: 187: 182: 173: 172: 170: 168: 164: 160: 156: 154: 150: 146: 142: 140: 136: 132: 129:TE/TET/TC/TCY 128: 124: 120: 118: 114: 108: 61: 59:Pronunciation 57: 54:Clinical data 52: 48: 43: 39: 34: 26: 22: 6209:Hepatotoxins 6199:Carboxamides 6133: 6113:Ketoconazole 6110:Antagonists: 6109: 6083:Troglitazone 6058:Tetracycline 6057: 6013:Spiroxatrine 5958:Quingestrone 5953:Progesterone 5938:Pregnenolone 5933:Pregnanolone 5923:Pregnanediol 5918:Prednisolone 5843:Mifepristone 5770: 5745:Griseofulvin 5725:Fenbendazole 5710:Famprofazone 5705:Erythromycin 5700:Epothilone B 5685:Eburnamonine 5580:Clotrimazole 5570:Clofenvinfos 5505:Antimycotics 5436: 5399:Okadaic acid 5351:Antagonists: 5350: 5339:Troglitazone 5274:Mifepristone 5269:Methoxychlor 5264:Griseofulvin 5259:Ellagic acid 5239:Cypermethrin 5229:Clotrimazole 5180: 5083:Prednisolone 5045:Tetracycline 5044: 4830:Quinupristin 4826:Dalfopristin 4754:Lincosamides 4691:Tildipirosin 4661:Oleandomycin 4626:Erythromycin 4596:Azithromycin 4432:Tetracycline 4431: 4407:Omadacycline 4392:Meclocycline 4382:Eravacycline 4372:Clomocycline 4287:Micronomicin 4260: 4235:Hygromycin B 4224:+loteprednol 4182:Ribostamycin 4155:Streptomycin 4145:Streptomyces 4143: 3965:Combinations 3900:Isotretinoin 3847:Drospirenone 3837:Bicalutamide 3789:Erythromycin 3695:Tea tree oil 3675:Azelaic acid 3608:Tirbanibulin 3562:Tromantadine 3471:Sulfonamides 3433:Fusidic acid 3429: 3401:Nadifloxacin 3349:Tetracycline 3348: 3325:Tetracycline 3324: 3174:Tetracycline 3173: 3159:Oxyquinoline 3094:Clotrimazole 2963:. Retrieved 2955:The Observer 2954: 2944: 2911: 2907: 2900: 2888:. Retrieved 2884:the original 2880:SyFy Channel 2879: 2870: 2845: 2841: 2834: 2822:. Retrieved 2814:Boston Globe 2813: 2791: 2787: 2781: 2748: 2744: 2738: 2706:(1): 76–82. 2703: 2699: 2689: 2664: 2660: 2650: 2625: 2621: 2611: 2578: 2574: 2568: 2556:. Retrieved 2552:the original 2541: 2506: 2502: 2492: 2457: 2453: 2443: 2431:. Retrieved 2422: 2412: 2400:. Retrieved 2396: 2387: 2375:. Retrieved 2360: 2348:. Retrieved 2344:the original 2337: 2328: 2319: 2313: 2304: 2298: 2289: 2280: 2269:, retrieved 2257: 2248: 2236:. Retrieved 2224: 2184: 2180: 2174: 2162:. Retrieved 2153: 2144: 2136:the original 2107: 2103: 2093: 2085:the original 2080: 2071: 2063:the original 2052: 2041:the original 2036: 2024: 1989: 1985: 1975: 1940: 1937:Cell Reports 1936: 1926: 1917: 1909:10665/325771 1900: 1891: 1867: 1860: 1822:(1): 17–32. 1819: 1815: 1793: 1781:. Retrieved 1735: 1726: 1714:. Retrieved 1705: 1682:dengue fever 1678:yellow fever 1667: 1661: 1645: 1624: 1617: 1605: 1602: 1591: 1583:Boston Globe 1581: 1579: 1566: 1559: 1552: 1504: 1475: 1458: 1450:Pharmacology 1421: 1393:methotrexate 1319:, and other 1294: 1272: 1262: 1255: 1248: 1241: 1229: 1209:verification 1202: 1178:Side effects 1165: 1161:fluorescence 1153: 1109: 1093: 1076: 1067: 1059:mitochondria 1051: 1047:meningococci 1040: 1032: 1024: 1021:Lyme disease 1016: 997:Lyme disease 989:spirochaetal 982: 976: 970: 960: 954: 947: 936: 929: 911: 903:Medical uses 896:Streptomyces 894: 884: 861: 835:, including 821:Tetracycline 820: 819: 808:   391:Elimination 347:Legal status 341:Legal status 186:Tetracycline 167:License data 30:Tetracycline 25: 6214:Otologicals 6204:Dermatoxins 6098:Zafirlukast 6068:Thiothixene 6048:Terconazole 5998:Simvastatin 5873:Nisoldipine 5868:Nilvadipine 5853:Nicardipine 5823:Metacycline 5650:Dimercaprol 5605:Demecolcine 5565:Clindamycin 5560:Ciglitazone 5510:Artemisinin 5490:Ambrisentan 5394:Nigramide J 5329:Telmisartan 5289:Nicardipine 5199:Benfuracarb 5194:Artemisinin 5097:anesthetics 5035:Polymyxin B 4960:Acetic acid 4880:from market 4816:Linopristin 4762:Clindamycin 4739:Cethromycin 4666:Rokitamycin 4651:Midecamycin 4646:Kitasamycin 4563:Florfenicol 4540:Amphenicols 4484:inhibitors) 4450:Tigecycline 4427:Sarecycline 4402:Minocycline 4397:Metacycline 4387:Lymecycline 4362:Doxycycline 4206:Bekanamycin 4177:Paromomycin 4135:inhibitors) 4028:from market 3936:Epristeride 3920:Trifarotene 3905:Motretinide 3813:Doxycycline 3808:Minocycline 3803:Lymecycline 3779:Clindamycin 3771:Antibiotics 3746:Niacinamide 3705:Keratolytic 3577:Ibacitabine 3532:Idoxuridine 3527:Penciclovir 3443:Tyrothricin 3316:Antibiotics 3295:Antibiotics 3249:Epinephrine 3244:Benzydamine 3239:Becaplermin 3164:Polynoxylin 3144:Minocycline 3129:Mepartricin 3109:Doxycycline 3066:antiseptics 3024:prophylaxis 2824:18 November 2794:(4): 50–53. 2057:Mayton CA. 1599:Brand names 1539:Minocycline 1486:efflux pump 1444:doxycycline 1375:fatty liver 1356:or intense 1340:indigestion 1203:needs more 1037:psittacosis 1009:brucellosis 845:brucellosis 735: g·mol 678:100.000.438 580:CHEBI:27902 413:Identifiers 153:MedlinePlus 126:Other names 117:Trade names 6189:Biomarkers 6173:Categories 6078:Tianeptine 6043:Tenylidone 6038:Tacrolimus 5983:Rimexolone 5973:Rifampicin 5913:Plicamycin 5898:Paclitaxel 5883:Omeprazole 5863:Nifedipine 5838:Mevastatin 5833:Metyrapone 5813:Lovastatin 5808:Loratadine 5765:Hyperforin 5755:Haloprogin 5720:Felodipine 5695:Enzacamene 5675:Dronabinol 5640:Diclazuril 5619:prasterone 5575:Chloroxine 5550:Cephradine 5520:Bile acids 5334:Tolnaftate 5299:Permethrin 5284:Nevirapine 5279:Nefazodone 5248:prasterone 5209:Carvedilol 5189:Amiodarone 5160:modulators 5093:Analgesics 5015:Miconazole 5005:Gentamicin 5000:Clioquinol 4980:Boric acid 4812:Flopristin 4772:Pirlimycin 4767:Lincomycin 4716:Tylvalosin 4696:Tilmicosin 4681:Spiramycin 4656:Miocamycin 4611:Carrimycin 4606:Carbomycin 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Index

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Trade names
AHFS
Drugs.com
Monograph
MedlinePlus
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By mouth
ATC code
A01AB13
WHO
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WHO
J01AA07
WHO
S01AA09
WHO
S02AA08
WHO
S03AA02
WHO
QG01AA90

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