Knowledge

Atomoxetine

Source 📝

2374: 713: 690: 2362: 40: 31: 2324: 2390: 5095: 19647: 5083: 5904: 2431:
patent on Strattera, increasing the likelihood of an earlier entry of a generic into the US market. On 1 September 2010, Sun Pharmaceuticals announced it would begin manufacturing a generic in the United States. In a 29 July 2011 conference call, however, Sun Pharmaceutical's Chairman stated "Lilly won that litigation on appeal so I think 's deferred."
5923: 990:
The initial therapeutic effects of atomoxetine usually take 1 to 4 weeks to become apparent. A further 2 to 4 weeks may be required for the full therapeutic effects to be seen. Incrementally increasing response may occur up to 1 year or longer. The maximum recommended total daily dose in children and
2430:
as an antidepressant, but it was found to be insufficiently efficacious for treating depression. It was, however, found to be effective for ADHD and was approved by the FDA in 2002, for the treatment of ADHD. Its patent expired in May 2017. On 12 August 2010, Lilly lost a lawsuit that challenged its
959:
While its efficacy may be less than that of amphetamine, there is some evidence that it may be used in combination with stimulants. Doctors may prescribe non-stimulants including atomoxetine when a person has bothersome side effects from stimulants; when a stimulant was not effective; in combination
2257:
The half-life of atomoxetine varies widely between individuals, with an average range of 4.5 to 19 hours. As atomoxetine is metabolized by CYP2D6, exposure may be increased 10-fold in CYP2D6 poor metabolizers. Among CYP2D6 extensive metabolizers, the half-life of atomoxetine averaged 5.34 hours and
2458:
In India, atomoxetine is sold under brand names including Axetra, Axepta, Attera, Tomoxetin, and Attentin. In Australia, Canada, Italy, Portugal, Romania, Spain, Switzerland and the US, atomoxetine is sold under the brand name Strattera. In the Czech Republic it is sold under brand names including
881:
of self-motivation, sustained attention, inhibition, working memory, reaction time and emotional self-regulation. Use of atomoxetine is only recommended for those who are at least six years old. It is taken orally. The effectiveness of atomoxetine is comparable to the commonly prescribed stimulant
2311:
Atomoxetine is excreted unchanged in urine at <3% in both extensive and poor CYP2D6 metabolizers, with >96% and 80% of a total dose being excreted in urine, respectively. The fractions excreted in urine as 4-hydroxyatomoxetine and its glucuronide account for 86% of a given dose in extensive
2405:
Atomoxetine may be quantitated in plasma, serum or whole blood in order to distinguish extensive versus poor metabolizers in those receiving the drug therapeutically, to confirm the diagnosis in potential poisoning victims or to assist in the forensic investigation in a case of fatal overdosage.
4795:
Wernicke JF, Adler L, Spencer T, West SA, Allen AJ, Heiligenstein J, et al. (February 2004). "Changes in symptoms and adverse events after discontinuation of atomoxetine in children and adults with attention deficit/hyperactivity disorder: a prospective, placebo-controlled assessment".
5369:
The noradrenergic action also exerts an important clinical effect in different antidepressant classes such as desipramine and nortriptyline (tricyclics, prevalent noradrenergic effect), reboxetine and atomoxetine (relatively pure noradrenergic reuptake inhibitor (NRIs)), and dual action
3733:
Stuhec M, Munda B, Svab V, Locatelli I (June 2015). "Comparative efficacy and acceptability of atomoxetine, lisdexamfetamine, bupropion and methylphenidate in treatment of attention deficit hyperactivity disorder in children and adolescents: a meta-analysis with focus on bupropion".
4258:
Fırat S, Gul H, Aysev A (July 2021). "An Open-Label Trial of Methylphenidate Treating Sluggish Cognitive Tempo, Inattention, and Hyperactivity/Impulsivity Symptoms Among 6- to 12-Year-Old ADHD Children: What Are the Predictors of Treatment Response at Home and School?".
2099:
in rat cortical neurons at therapeutic concentrations. It causes a use-dependent open-channel block and its binding site overlaps with the Mg binding site. Atomoxetine's ability to increase prefrontal cortex firing rate in anesthetized rats could not be blocked by
3829:
Koda K, Ago Y, Cong Y, Kita Y, Takuma K, Matsuda T (July 2010). "Effects of acute and chronic administration of atomoxetine and methylphenidate on extracellular levels of noradrenaline, dopamine and serotonin in the prefrontal cortex and striatum of mice".
10148: 2459:
Mylan. In Poland, it is sold under the brand name Auroxetyn. In Iran, atomoxetine is sold under brand names including Stramox. In Brazil, it is sold under the brand name Atentah. In Turkey it is sold under the brand names including Attex. In 2017, a
5370:
antidepressants such as the serotonin noradrenaline reuptake inhibitors (SNRIs), the noradrenergic and dopaminergic reuptake inhibitor (NDRI) bupropion, and other compounds (e.g., mianserin, mirtazapine), which enhance the noradrenergic transmission
8984: 4173:
McBurnett K, Clemow D, Williams D, Villodas M, Wietecha L, Barkley R (February 2017). "Atomoxetine-Related Change in Sluggish Cognitive Tempo Is Partially Independent of Change in Attention-Deficit/Hyperactivity Disorder Inattentive Symptoms".
3005:
McBurnett K, Clemow D, Williams D, Villodas M, Wietecha L, Barkley R (February 2017). "Atomoxetine-Related Change in Sluggish Cognitive Tempo Is Partially Independent of Change in Attention-Deficit/Hyperactivity Disorder Inattentive Symptoms".
5334:
Ding YS, Naganawa M, Gallezot JD, Nabulsi N, Lin SF, Ropchan J, et al. (February 2014). "Clinical doses of atomoxetine significantly occupy both norepinephrine and serotonin transports: Implications on treatment of depression and ADHD".
2196:-coupled receptors. Therapeutic concentrations of atomoxetine are within range of interacting with GIRKs, especially in CYP2D6 poor metabolizers. It is not known whether this contributes to the therapeutic effects of atomoxetine in ADHD. 2486:. As with other norepinephrine reuptake inhibitors it appears to reduce anxiety and depression symptoms, although attention has focused mainly on specific patient groups such as those with concurrent ADHD or methamphetamine dependence. 4668:"Safety of 80 antidepressants, antipsychotics, anti-attention-deficit/hyperactivity medications and mood stabilizers in children and adolescents with psychiatric disorders: a large scale systematic meta-review of 78 adverse effects" 6030: 2645: 4630:
Kim YW, Shin JC, An YS (July 2010). "Treatment of chronic akinetic mutism with atomoxetine: subtraction analysis of brain f-18 fluorodeoxyglucose positron emission tomographic images before and after medication: a case report".
8605: 2083:
in the prefrontal cortex following acute or chronic atomoxetine treatment. Supporting atomoxetine's selectivity, a human study found no effects on platelet serotonin uptake (a marker of SERT inhibition) and inhibition of the
1202:
for suicidal behavior/ideation. Similar warnings have been issued in Australia. Unlike stimulant medications, atomoxetine does not have abuse liability or the potential to cause withdrawal effects on abrupt discontinuation.
2060:, was found to increase prefrontal, striatal, and accumbal dopamine levels to the same degree. In addition to rats, atomoxetine has also been found to induce similar region-specific catecholamine level alteration in mice. 8924: 3865:
Schulz KP, Fan J, Bédard AC, Clerkin SM, Ivanov I, Tang CY, et al. (September 2012). "Common and unique therapeutic mechanisms of stimulant and nonstimulant treatments for attention-deficit/hyperactivity disorder".
5779:
Sauer JM, Ponsler GD, Mattiuz EL, Long AJ, Witcher JW, Thomasson HR, et al. (January 2003). "Disposition and metabolic fate of atomoxetine hydrochloride: the role of CYP2D6 in human disposition and metabolism".
3309:
Kamradt JM, Ullsperger JM, Nikolas MA (December 2014). "Executive function assessment and adult attention-deficit/hyperactivity disorder: tasks versus ratings on the Barkley deficits in executive functioning scale".
5173:
Creighton CJ, Ramabadran K, Ciccone PE, Liu J, Orsini MJ, Reitz AB (August 2004). "Synthesis and biological evaluation of the major metabolite of atomoxetine: elucidation of a partial kappa-opioid agonist effect".
967:
Atomoxetine alleviates ADHD symptoms through norepinephrine reuptake and by indirectly increasing dopamine in the pre-frontal cortex, sharing 70-80% of the brain regions with stimulants in their produced effects.
3144:"A systematic review of combination therapy with stimulants and atomoxetine for attention-deficit/hyperactivity disorder, including patient characteristics, treatment strategies, effectiveness, and tolerability" 3224:
Isfandnia F, El Masri S, Radua J, Rubia K (July 2024). "The effects of chronic administration of stimulant and non-stimulant medications on executive functions in ADHD: A systematic review and meta-analysis".
2678: 2227:
of 63% for extensive metabolizers and 94% for poor metabolizers. Maximum plasma concentration is reached in 1–2 hours. If taken with food, the maximum plasma concentration decreases by 10–40% and delays the
5507:
Di Miceli M, Gronier B (June 2015). "Psychostimulants and atomoxetine alter the electrophysiological activity of prefrontal cortex neurons, interaction with catecholamine and glutamate NMDA receptors".
19223: 4739: 8480: 8186: 6242: 14408: 940:
Atomoxetine is approved for use in children, adolescents, and adults. However, its efficacy has not been studied in children under six years old. One of the primary differences with the standard
6250:
Atomoxetine (Strattera) has also been researched in controlled studies for treatment of ADHD in children with autism, and showed some improvements, particularly for hyperactivity and impulsivity
5982: 10936: 10840: 10753: 10681: 2246:
of 0.85 L/kg (indicating distribution primarily in total body water), with limited partitioning into red blood cells. It is highly bound to plasma proteins (98.7%), mainly albumin, along with α
18371: 18366: 18361: 17689: 16607: 16602: 16597: 5295:"Effects of acute and chronic administration of atomoxetine and methylphenidate on extracellular levels of noradrenaline, dopamine and serotonin in the prefrontal cortex and striatum of mice" 4032:
Clemow DB, Bushe CJ (December 2015). "Atomoxetine in patients with ADHD: A clinical and pharmacological review of the onset, trajectory, duration of response and implications for patients".
960:
with a stimulant to increase effectiveness; when the cost of stimulants is prohibitive; or when there is concern about the abuse potential of psychostimulants in a patient with a history of
17087: 9966: 6038: 5464:
Barygin OI, Nagaeva EI, Tikhonov DB, Belinskaya DA, Vanchakova NP, Shestakova NN (April 2017). "Inhibition of the NMDA and AMPA receptor channels by antidepressants and antipsychotics".
18944: 8734: 6305:
Rabiey A, Hassani-Abharian P, Farhad M, Moravveji AR, Akasheh G, Banafshe HR (December 2019). "Atomoxetine Efficacy in Methamphetamine Dependence during Methadone Maintenance Therapy".
3404:"Comparative efficacy of methylphenidate and atomoxetine in the treatment of attention deficit hyperactivity disorder in children and adolescents: A systematic review and meta-analysis" 18070: 7915: 6262:
Snircova E, Marcincakova-Husarova V, Hrtanek I, Kulhan T, Ondrejka I, Nosalova G (June 2016). "Anxiety reduction on atomoxetine and methylphenidate medication in children with ADHD".
5216:"Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder" 245: 17804: 2029:(NET), preventing the reuptake of norepinephrine throughout the brain along with inhibiting the reuptake of dopamine in specific brain regions such as the prefrontal cortex, where 5902:, Bryan B. Molloy & Klaus K. Schmiegel, "Aryloxyphenylpropylamines in treating depression", published 19 April 1977, assigned to Eli Lilly And Company 7935: 19215: 3350:"Comparative efficacy and acceptability of methylphenidate and atomoxetine in treatment of attention deficit hyperactivity disorder in children and adolescents: a meta-analysis" 2308:-desmethylatomoxetine at steady state are 1.0% and 5% that of atomoxetine in CYP2D6 extensive metabolizers, and are 5% and 45% that of atomoxetine in CYP2D6 poor metabolizers. 7969: 3777: 2775: 1191:
is not clear; a 2018 review stated that, "ecause of lack of data, the treating physician should consider stopping atomoxetine treatment in women with ADHD during pregnancy."
17082: 19672: 19395: 17498: 4211:"Atomoxetine improved attention in children and adolescents with attention-deficit/hyperactivity disorder and dyslexia in a 16 week, acute, randomized, double-blind trial" 3092:"Atomoxetine improved attention in children and adolescents with attention-deficit/hyperactivity disorder and dyslexia in a 16 week, acute, randomized, double-blind trial" 5921:, Bennie Joe Foster & Edward Ralph Lavagnino, "3-aryloxy-3-phenylpropylamines", published 29 February 1984, assigned to Eli Lilly And Company 19428: 18696: 17944: 16987: 8705: 5751: 2816: 2574: 16271: 3510:"A network meta-analysis of atomoxetine and osmotic release oral system methylphenidate in the treatment of attention-deficit/hyperactivity disorder in adult patients" 5054: 3807: 2667: 19717: 19210: 18115: 17824: 16266: 8851: 6407: 916:
It was approved for medical use in the United States in 2002. In 2021, it was the 219th most commonly prescribed medication in the United States, with more than 1.9
14068: 14019: 10517: 10369: 9959: 1334:
Highly plasma protein-bound drugs: atomoxetine has the potential to displace these drugs from plasma proteins which may potentiate their adverse or toxic effects.
6052: 2569:[Collegiate Board Resolution No. 816 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). 14100: 12784: 12629: 6987: 1971: 1947: 1923: 8666: 4573:
Atomoxetine is a nonstimulant drug used to treat ADHD (Perwien et al., 2006) that acts as a presynaptic blocker of noradrenalin reuptake (Swanson et al., 2006).
19321: 19109: 16517: 16326: 14443: 10978: 9932: 7908: 11580: 18195: 4715: 3906:"Systematic review of atomoxetine data in childhood and adolescent attention-deficit hyperactivity disorder 2009-2011: focus on clinical efficacy and safety" 3212:
Though not FDA-approved for combined treatment, atomoxetine (Strattera) is sometimes used in conjunction with stimulants as an off-label combination therapy.
200: 11451: 6233: 16468: 13901: 13896: 13886: 8363: 6737: 5255:
Hodgkins P, Shaw M, McCarthy S, Sallee FR (March 2012). "The pharmacology and clinical outcomes of amphetamines to treat ADHD: does composition matter?".
1064:
identified only one study of atomoxetine for TBI and found no positive effects. Aside from TBI, atomoxetine was found to be effective in the treatment of
19316: 18190: 13836: 13125: 9952: 9925: 6656: 11509: 11504: 19433: 5970: 4126:"Report of a Work Group on Sluggish Cognitive Tempo: Key Research Directions and a Consensus Change in Terminology to Cognitive Disengagement Syndrome" 4077:"Report of a Work Group on Sluggish Cognitive Tempo: Key Research Directions and a Consensus Change in Terminology to Cognitive Disengagement Syndrome" 3043:"Report of a Work Group on Sluggish Cognitive Tempo: Key Research Directions and a Consensus Change in Terminology to Cognitive Disengagement Syndrome" 2262:-desmethylatomoxetine was 8.9 hours. By contrast, among CYP2D6 poor metabolizers the half-life of atomoxetine averaged 20.0 hours and the half-life of 834: 16527: 11575: 6091: 2199:
4-Hydroxyatomoxetine, the major active metabolite of atomoxetine in CYP2D6 extensive metabolizers, has been found to have sub-micromolar affinity for
2015:(nM). The smaller the value, the more strongly the drug binds to the site. All values are for human receptors unless otherwise specified. rat cortex. 258: 19677: 17072: 16537: 10974: 7901: 889:
Common side effects of atomoxetine include abdominal pain, loss of appetite, nausea, feeling tired, and dizziness. Serious side effects may include
18085: 17558: 11461: 11171: 11111: 11016: 9248: 8373: 6873: 6398: 5693:"Inhibition of G-protein-activated inwardly rectifying K+ channels by the selective norepinephrine reuptake inhibitors atomoxetine and reboxetine" 776: 19602: 19243: 19235: 18296: 17754: 17639: 17448: 17295: 6954: 19512: 19276: 17553: 13970: 12591: 11336: 11281: 11276: 11241: 10522: 10374: 8690: 3198:(Guidelines (Tertiary source)). American Psychiatric Association & American Academy of Child and Adolescent Psychiatry (AACAP). June 2013. 2304:, but inhibit CYP2D6 in human liver microsomes at concentrations between 3.6 and 17 μmol/L. Plasma concentrations of 4-hydroxyatomoxetine and 1211:
Atomoxetine is relatively non-toxic in overdose. Single-drug overdoses involving over 1500 mg of atomoxetine have not resulted in death.
19291: 18616: 18501: 17894: 17249: 16912: 16572: 13452: 13215: 13145: 12074: 11931: 11806: 11550: 11398: 11361: 11261: 11256: 11156: 11141: 11136: 11101: 10941: 10931: 10845: 10830: 10758: 10748: 10686: 10676: 10649: 10069: 9833: 9084: 8856: 8675: 6348: 2722: 85: 3199: 2983: 19438: 19408: 19359: 19079: 19069: 18170: 18165: 17674: 16388: 15930: 15925: 15206: 15201: 15020: 12771: 12194: 12169: 12084: 11731: 11721: 11311: 11301: 11271: 11266: 11231: 11186: 11131: 11121: 11116: 10644: 10359: 10089: 10084: 9602: 9587: 9119: 8989: 8949: 8292: 7769: 7020: 5382:
Zerbe RL, Rowe H, Enas GG, Wong D, Farid N, Lemberger L (January 1985). "Clinical pharmacology of tomoxetine, a potential antidepressant".
790: 10593: 10286: 6079: 5553:"Atomoxetine affects transcription/translation of the NMDA receptor and the norepinephrine transporter in the rat brain--an in vivo study" 2135:
protein content without altering transcript levels. Aberrant glutamate and NMDA receptor function have been implicated in the etiology of
1016:) have found that it is an effective treatment. In contrast, multiple RCTs have shown that it responds poorly to the stimulant medication 19547: 19019: 18873: 18536: 18351: 17994: 17403: 14093: 13654: 12776: 12756: 12741: 12711: 12129: 12039: 11471: 11376: 11366: 11346: 11326: 11306: 10049: 9838: 9818: 9813: 9770: 9597: 9567: 9258: 9156: 9129: 9079: 9046: 9026: 9021: 8964: 8959: 8944: 8934: 8914: 8909: 8500: 8460: 8408: 8146: 8081: 8071: 8066: 6725: 859: 193: 19458: 19448: 18641: 17654: 15709: 13690: 13447: 13442: 13427: 12731: 11645: 11428: 10951: 10855: 10768: 10696: 10532: 10512: 10391: 10364: 10215: 10099: 9114: 9099: 8871: 8866: 8754: 6731: 3545: 2343:
Japanese men homozygous for CYP2D6*10 have similarly been found to experience two-fold higher AUCs compared to extensive metabolizers.
3483: 19494: 19463: 19364: 19251: 19104: 19084: 18974: 18954: 18681: 18004: 17002: 16632: 16306: 16047: 14438: 14433: 12179: 12159: 11555: 11535: 10173: 9634: 9629: 9624: 9619: 9151: 8571: 8046: 6771: 4761: 2925:
Brown JT, Bishop JR (2015). "Atomoxetine pharmacogenetics: associations with pharmacokinetics, treatment response and tolerability".
2373: 1159:
Common side effects include abdominal pain, loss of appetite, nausea, feeling tired, and dizziness. Serious side effects may include
18686: 18250: 18039: 17139: 16461: 16431: 13472: 12794: 12443: 11540: 6650: 6475: 5119:"A review of the abuse potential assessment of atomoxetine: a nonstimulant medication for attention-deficit/hyperactivity disorder" 4304:"Sluggish Cognitive Tempo as a Possible Predictor of Methylphenidate Response in Children With ADHD: A Randomized Controlled Trial" 3769: 2767: 866: 19687: 19682: 19174: 19099: 19094: 19029: 13710: 11663: 10054: 8241: 6815: 4547:
Termine C, Selvini C, Rossi G, Balottin U (2013). "Emerging treatment strategies in Tourette syndrome: what's in the pipeline?".
3630:
Ornoy A (February 2018). "Pharmacological Treatment of Attention Deficit Hyperactivity Disorder During Pregnancy and Lactation".
2337: 1265:
has been reported with atomoxetine at therapeutic doses and in overdose; it is suggested that atomoxetine not be used with other
2637: 2604: 17398: 14428: 14086: 11560: 11486: 10946: 10926: 10850: 10825: 10763: 10743: 10691: 10671: 10562: 10421: 10210: 10094: 9134: 8969: 8383: 8216: 8151: 6719: 2312:
metabolizers, but only 40% in poor metabolizers. CYP2D6 poor metabolizers excrete greater amounts of minor metabolites, namely
5740: 3711: 3605: 2511: 19722: 14005: 12495: 9016: 7826: 5954: 5883: 5651:
Chang JP, Lane HY, Tsai GE (2014). "Attention deficit hyperactivity disorder and N-methyl-D-aspartate (NMDA) dysregulation".
4841:"Evaluation of a Potential Metabolism-Mediated Drug-Drug Interaction Between Atomoxetine and Bupropion in Healthy Volunteers" 4016: 3681: 2808: 2566: 5039: 12935: 12913: 11009: 6391: 3799: 2162: 1847: 1828: 6360: 19707: 17052: 16454: 16415: 12808: 9986: 7053: 6661: 6189:
Perugi G, Vannucchi G (2015). "The use of stimulants and atomoxetine in adults with comorbid ADHD and bipolar disorder".
4422: 19692: 14781: 13737: 11042: 10661: 10262: 9853: 8680: 6921: 6059: 2562: 2219:
Orally administered atomoxetine is rapidly and completely absorbed. First-pass metabolism by the liver is dependent on
1291: 841: 136: 4388: 4353:"Attention deficit disorder with and without hyperactivity: clinical response to three dose levels of methylphenidate" 2075:
found that atomoxetine occupied >90% and >85% of neural NET and SERT, respectively. However, both mouse and rat
10877: 10778: 10706: 10602: 10453: 10295: 10109: 9995: 6701: 6173: 3578: 810: 18816: 16230: 12007: 7843: 6232:
Siegel M, Erickson C, Frazier JA, Ferguson T, Goepfert E, Joshi G, et al. (Autism Society of America) (2016).
5214:
Bymaster FP, Katner JS, Nelson DL, Hemrick-Luecke SK, Threlkeld PG, Heiligenstein JH, et al. (November 2002).
3262:"The World Federation of ADHD International Consensus Statement: 208 Evidence-based conclusions about the disorder" 2361: 1057: 1005: 870: 18811: 12698: 12518: 11002: 9975: 6384: 1305: 395: 230: 117: 18736: 16435: 8838: 4887:"Cardiovascular side effects of atomoxetine and its interactions with inhibitors of the cytochrome p450 system" 1183:, rating it as a "potentially least preferred agent based on safety" for treating ADHD. As of 2019, safety in 818:
InChI=1S/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3/t17-/m1/s1
490: 15491: 13265: 12995: 8586: 7924: 6764: 2567:"RDC Nº 816 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" 17934: 16411: 14128: 14109: 14064: 10970: 9918: 6085: 5978: 5048: 3402:
Rezaei G, Hosseini SA, Akbari Sari A, Olyaeemanesh A, Lotfi MH, Yassini M, et al. (10 February 2016).
2570: 2068: 1790: 1266: 1195: 1142: 708: 557: 3448:"Core ADHD symptom improvement with atomoxetine versus methylphenidate: a direct comparison meta-analysis" 19504: 15775: 15051: 14044: 9213: 7426: 7359: 6683: 5094:. University of North Carolina at Chapel Hill and the United States National Institute of Mental Health. 3260:
Faraone SV, Banaschewski T, Coghill D, Zheng Y, Biederman J, Bellgrove MA, et al. (September 2021).
2534:"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)" 2336:
Chinese adults homozygous for the hypoactive CYP2D6*10 allele have been found to exhibit two-fold higher
2267: 2254:-desmethylatomoxetine is 99.1% bound to plasma proteins, while 4-hydroxyatomoxetine is only 66.6% bound. 2211:. It is not known whether this action at the kappa-opioid receptor leads to CNS-related adverse effects. 2169: 2057: 1771: 1295: 1013: 1009: 669: 5918: 2355:)-3-(2-methylphenoxy)-3-phenylpropylamine, is a white, granular powder that is highly soluble in water. 19667: 19637: 18914: 18909: 18301: 17644: 16732: 14770: 14282: 10143: 9006: 7189: 7097: 6695: 2026: 1809: 1431: 658: 5899: 650: 19712: 18934: 17924: 17649: 16967: 14030: 13604: 12927: 12825: 12509: 12021: 7201: 6666: 2533: 2482:
although such use has not been well studied. Some benefit has also been seen in people with ADHD and
987:, atomoxetine's use can be abruptly stopped without significant discontinuation effects being seen. 18904: 18846: 18306: 18065: 17310: 13932: 13850: 13751: 13668: 13537: 12960: 12857: 12689: 12458: 8639: 6757: 6532: 6524: 2096: 1325: 1220: 1112: 972: 685: 4209:
Wietecha L, Williams D, Shaywitz S, Shaywitz B, Hooper SR, Wigal SB, et al. (November 2013).
3090:
Wietecha L, Williams D, Shaywitz S, Shaywitz B, Hooper SR, Wigal SB, et al. (November 2013).
2714: 1243:-desmethylatomoxetine levels and decrease plasma 4-hydroxyatomoxetine levels by a similar degree. 19484: 18899: 17523: 17305: 16248: 13878: 13814: 13150: 11056: 9868: 7831: 6438: 5117:
Upadhyaya HP, Desaiah D, Schuh KJ, Bymaster FP, Kallman MJ, Clarke DO, et al. (March 2013).
4985:
Scherer D, Hassel D, Bloehs R, Zitron E, von Löwenstern K, Seyler C, et al. (January 2009).
4124:
Becker SP, Willcutt EG, Leopold DR, Fredrick JW, Smith ZR, Jacobson LA, et al. (June 2023).
4075:
Becker SP, Willcutt EG, Leopold DR, Fredrick JW, Smith ZR, Jacobson LA, et al. (June 2023).
3191: 3041:
Becker SP, Willcutt EG, Leopold DR, Fredrick JW, Smith ZR, Jacobson LA, et al. (June 2023).
2975: 2434:
In 2017 the FDA approved the generic production of atomoxetine by four pharmaceutical companies.
1107: 1069: 173: 95: 52: 19702: 18311: 17325: 17300: 17199: 16427: 16423: 15830: 15106: 14536: 14489: 13682: 13618: 13009: 11975: 11966: 11530: 11517: 11499: 11441: 11065: 10153: 10019: 9743: 9218: 9011: 8823: 8814: 7666: 7137: 6418: 5602:
Maltezos S, Horder J, Coghlan S, Skirrow C, O'Gorman R, Lavender TJ, et al. (March 2014).
2243: 1037: 630: 622: 335: 5946: 5939: 4488:
Arnts H, van Erp WS, Lavrijsen JC, van Gaal S, Groenewegen HJ, van den Munckhof P (May 2020).
18466: 16762: 15548: 15480: 14954: 14256: 13646: 13547: 9944: 9738: 7107: 6713: 6471: 2419: 2394: 2340:(AUCs) and 1.5-fold higher maximum plasma concentrations compared to extensive metabolizers. 2275: 2271: 2208: 2183: 2085: 2064: 1402: 546: 481: 16542: 16522: 16419: 16291: 15820: 15364: 15096: 14526: 14505: 14117: 13240: 11771: 11706: 11686: 8861: 8576: 8317: 7893: 7786: 7701: 6677: 4666:
Solmi M, Fornaro M, Ostinelli EG, Zangani C, Croatto G, Monaco F, et al. (June 2020).
3509: 3447: 2176: 2030: 1885: 1866: 1459: 1029: 574: 566: 538: 437: 429: 361: 18279: 17622: 16488: 4773: 2471:
There has been some suggestion that atomoxetine might be a helpful adjunct in people with
1536: 1507: 1480: 8: 19697: 19607: 19193: 19039: 18999: 18326: 18145: 18125: 17423: 17385: 17340: 16105: 15950: 15815: 15543: 15400: 15226: 15091: 14746: 14521: 13891: 12029: 11433: 9223: 8629: 8056: 7954: 7612: 7552: 4839:
Todor I, Popa A, Neag M, Muntean D, Bocsan C, Buzoianu A, et al. (April–June 2016).
4716:"Psychiatric drugs given to children and adolescents have been ranked in order of safety" 2270:
levels of atomoxetine are typically achieved at or around day 10 of regular dosing, with
2239: 1117: 1097: 878: 420: 180: 9790: 4607: 4586: 3879: 2426:-filing company and current U.S. patent owner. Atomoxetine was initially intended to be 712: 689: 19139: 18446: 18135: 17869: 17759: 17413: 17093: 16877: 16717: 16677: 16480: 16190: 14216: 12301: 12296: 12199: 11906: 11676: 10314: 9978: 9166: 9161: 9001: 8845: 7927: 7884: 7881: 6803: 6799: 6466: 6287: 6214: 6141: 6114: 5848: 5805: 5717: 5692: 5628: 5603: 5579: 5552: 5533: 5489: 5438: 5413: 5360: 5143: 5118: 5011: 4986: 4967: 4913: 4886: 4821: 4809: 4731: 4692: 4667: 4560: 4529: 4380: 4328: 4303: 4284: 4235: 4210: 4150: 4125: 4101: 4076: 4057: 3984: 3957: 3935: 3655: 3537: 3475: 3420: 3403: 3376: 3349: 3286: 3261: 3168: 3143: 3116: 3091: 3067: 3042: 2902: 2460: 2204: 1904: 147: 18924: 18080: 17320: 5664: 5551:
Udvardi PT, Föhr KJ, Henes C, Liebau S, Dreyhaupt J, Boeckers TM, et al. (2013).
5412:
Ludolph AG, Udvardi PT, Schaz U, Henes C, Adolph O, Weigt HU, et al. (May 2010).
5232: 5215: 4987:"Selective noradrenaline reuptake inhibitor atomoxetine directly blocks hERG currents" 4302:
Froehlich TE, Becker SP, Nick TG, Brinkman WB, Stein MA, Peugh J, et al. (2018).
3508:
Bushe C, Day K, Reed V, Karlsdotter K, Berggren L, Pitcher A, et al. (May 2016).
3142:
Treuer T, Gau SS, Méndez L, Montgomery W, Monk JA, Altin M, et al. (April 2013).
18929: 18321: 18316: 18090: 17335: 16897: 16532: 16181: 14919: 14626: 14201: 13950: 13561: 13235: 12879: 12751: 11998: 11891: 11025: 9748: 8654: 8550: 8368: 8261: 7936: 7803: 7705: 7224: 6446: 6352: 6314: 6279: 6206: 6169: 6146: 5950: 5879: 5840: 5836: 5797: 5722: 5668: 5633: 5584: 5525: 5481: 5443: 5429: 5391: 5352: 5348: 5316: 5311: 5294: 5272: 5268: 5237: 5191: 5148: 5016: 5002: 4959: 4918: 4862: 4813: 4735: 4697: 4648: 4612: 4564: 4533: 4521: 4467: 4463: 4372: 4333: 4288: 4276: 4240: 4191: 4155: 4106: 4049: 4012: 3989: 3927: 3883: 3847: 3843: 3751: 3647: 3574: 3529: 3467: 3425: 3381: 3327: 3291: 3242: 3173: 3121: 3072: 3023: 2942: 2894: 2890: 2596: 2049: 2034: 1269:, concomitantly with CYP2D6 inhibitors, and caution to be used in poor metabolizers. 1199: 1053: 1049: 961: 949: 282: 270: 109: 6218: 5852: 5809: 5604:"Glutamate/glutamine and neuronal integrity in adults with ADHD: a proton MRS study" 5537: 5493: 5414:"Atomoxetine acts as an NMDA receptor blocker in clinically relevant concentrations" 5364: 4971: 4825: 4506: 4489: 4384: 4061: 3479: 3277: 3238: 2906: 2296:-desmethylatomoxetine, and 4-hydroxyatomoxetine produce minimal to no inhibition of 19329: 19266: 19089: 18805: 18731: 18456: 18185: 17939: 17779: 17493: 16752: 16286: 16141: 15513: 14909: 14606: 14546: 14363: 14277: 13728: 13225: 13140: 12940: 12659: 12448: 11786: 9303: 8620: 8566: 8344: 8282: 7959: 7866: 7776: 7719: 7655: 7502: 6450: 6291: 6271: 6241:. Washington, DC: American Academy of Child and Adolescent Psychiatry. p. 13. 6198: 6136: 6126: 5871: 5832: 5789: 5712: 5704: 5660: 5623: 5615: 5574: 5564: 5517: 5477: 5473: 5433: 5425: 5344: 5306: 5264: 5227: 5183: 5138: 5130: 5006: 4998: 4949: 4936:
Belle DJ, Ernest CS, Sauer JM, Smith BP, Thomasson HR, Witcher JW (November 2002).
4908: 4898: 4852: 4805: 4723: 4687: 4679: 4640: 4602: 4598: 4594: 4556: 4511: 4501: 4459: 4364: 4323: 4315: 4268: 4230: 4222: 4183: 4145: 4137: 4096: 4088: 4041: 3979: 3969: 3917: 3875: 3839: 3743: 3703: 3659: 3639: 3597: 3521: 3459: 3415: 3371: 3361: 3319: 3281: 3273: 3234: 3163: 3155: 3111: 3103: 3062: 3054: 3015: 2934: 2886: 2503: 2479: 2472: 2443: 2427: 2229: 2190: 1563: 1276: 1258: 1239:
has been shown to increase plasma atomoxetine by 100% or more, as well as increase
1136: 1123: 874: 725: 317: 213: 39: 6202: 5823:
Sauer JM, Ring BJ, Witcher JW (2005). "Clinical pharmacokinetics of atomoxetine".
4938:"Effect of potent CYP2D6 inhibition by paroxetine on atomoxetine pharmacokinetics" 3939: 3673: 3541: 2877:
Sauer JM, Ring BJ, Witcher JW (2005). "Clinical pharmacokinetics of atomoxetine".
2281:) residing around 30–40°ng/mL; however, both the time to steady-state levels and C 1175:, and aggression. A 2020 meta-analysis found that atomoxetine was associated with 956:
in children and adolescents. In adults, efficacy and tolerability are equivalent.
470: 462: 19651: 18979: 18506: 18461: 17809: 17784: 16827: 16757: 16612: 16503: 16477: 16256: 16131: 16073: 16061: 15729: 15368: 15000: 14934: 14348: 14236: 14211: 13980: 13975: 13945: 13774: 13769: 13372: 13337: 13327: 13292: 12899: 12874: 12341: 12034: 11916: 11071: 11033: 10168: 10034: 9803: 9753: 9513: 9433: 9398: 9298: 8739: 8649: 8418: 7994: 7715: 7709: 7522: 6896: 6555: 6461: 6456: 6442: 6004: 5875: 4644: 4411: 2317: 2224: 2200: 2153:
in a concentration-dependent, voltage-independent, and time-independent manner. K
2120: 2108: 2053: 1683: 1660: 1637: 1287: 1283: 1262: 1065: 1061: 1017: 953: 941: 883: 345: 325: 18919: 18075: 17315: 14078: 7875: 6784: 6338: 4419:
Attention-deficit hyperactivity disorder: A handbook for diagnosis and treatment
19281: 18606: 17904: 17884: 17879: 17684: 16942: 16902: 16892: 16852: 16747: 16712: 16617: 16592: 16547: 16085: 16069: 16065: 15991: 15714: 15380: 15372: 14985: 14751: 14474: 14226: 13955: 13911: 13502: 13402: 13312: 12986: 12842: 12785: 12630: 12586: 12541: 12286: 12276: 11896: 11816: 11413: 11316: 9713: 9693: 9458: 9393: 9313: 9293: 9089: 8561: 8490: 8277: 8196: 7837: 7279: 6988: 6886: 6780: 6689: 6342: 5187: 4954: 4937: 4141: 4092: 3058: 2235:
by 3 hours. Drugs affecting gastric pH have no effect on oral bioavailability.
2128: 1748: 1725: 1706: 1587: 1102: 11446: 11041: 6131: 5521: 5134: 3747: 3643: 3446:
Hazell PL, Kohn MR, Dickson R, Walton RJ, Granger RE, Wyk GW (November 2011).
952:
have found that atomoxetine has comparable efficacy and equal tolerability to
19661: 19597: 19256: 19034: 18989: 18939: 18862: 18850: 18556: 18471: 18451: 18436: 18431: 18376: 18150: 18140: 17844: 17764: 17488: 17428: 17418: 17355: 17330: 17124: 17067: 16857: 16802: 16792: 16787: 16767: 16702: 16652: 16637: 16552: 16446: 16341: 16125: 16121: 16091: 16057: 16031: 16021: 15976: 15940: 15800: 15744: 15583: 15523: 15445: 15425: 15408: 15386: 15307: 15302: 15252: 15216: 15076: 15015: 14741: 14261: 14246: 14206: 13965: 13858: 13804: 13789: 13575: 13512: 13245: 13190: 13185: 13175: 13130: 12950: 12884: 12736: 12546: 12531: 12376: 12069: 11951: 11791: 11671: 11650: 11625: 11545: 11166: 11161: 10492: 10339: 10163: 10079: 10029: 9883: 9878: 9858: 9718: 9683: 9538: 9533: 9523: 9498: 9493: 9428: 9388: 9348: 8929: 8634: 8546: 8485: 8430: 8398: 8257: 8191: 8011: 7984: 7727: 7674: 7462: 7334: 7309: 7304: 7244: 7219: 6634: 6603: 6563: 4450:
Ripley DL (2006). "Atomoxetine for individuals with traumatic brain injury".
4272: 4045: 3922: 3905: 3525: 3463: 3366: 2415: 2076: 2072: 2037: 1610: 1301: 1188: 945: 910: 701: 518: 295: 14358: 14353: 5110: 4587:"Pharmacotherapy for chronic cognitive impairment in traumatic brain injury" 2414:
Atomoxetine is manufactured, marketed, and sold in the United States as the
22: 19592: 19527: 19453: 19261: 18836: 18801: 18601: 18406: 18265: 17859: 17854: 17749: 17724: 17719: 17543: 17468: 17214: 17169: 17022: 17017: 16972: 16872: 16707: 16672: 16667: 16276: 16171: 16161: 15986: 15981: 15825: 15795: 15683: 15553: 15431: 15343: 15312: 15267: 15262: 15257: 15101: 15071: 14959: 14868: 14828: 14731: 14651: 14541: 14531: 14343: 14338: 14323: 14318: 14297: 13837: 13585: 13497: 13487: 13397: 13332: 13230: 13160: 13095: 13085: 13040: 12664: 12649: 12596: 12551: 12406: 12361: 12346: 12336: 12321: 12261: 11901: 11881: 11821: 11371: 11226: 11086: 10381: 10247: 10242: 9673: 9503: 9473: 9378: 9343: 9278: 9263: 9041: 8542: 8515: 8470: 8267: 8253: 8221: 8171: 8126: 7772: 7760: 7670: 7577: 7507: 7497: 7349: 7339: 7239: 7234: 7157: 7152: 7132: 7117: 7071: 6833: 6797: 6356: 6318: 6283: 6210: 6150: 5844: 5801: 5726: 5672: 5637: 5588: 5529: 5485: 5447: 5356: 5320: 5276: 5241: 5195: 5152: 5020: 4963: 4922: 4866: 4817: 4701: 4652: 4616: 4568: 4525: 4471: 4352: 4337: 4280: 4244: 4195: 4159: 4110: 4053: 3993: 3931: 3887: 3851: 3755: 3651: 3533: 3471: 3429: 3385: 3331: 3295: 3246: 3177: 3125: 3076: 3027: 2946: 2898: 1321: 1180: 1092: 1033: 208: 15636:
Selective serotonin reuptake inhibitors and serotonin receptor modulators:
6261: 5866:
Chamberlain SR, Sahakian BJ (2010). "Atomoxetine". In Stolerman IP (ed.).
5395: 4903: 4376: 4368: 4226: 4187: 3159: 3107: 3019: 2597:"Strattera 10mg hard capsules - Summary of Product Characteristics (SmPC)" 19522: 19499: 19413: 19339: 19306: 19286: 19164: 19149: 19144: 19134: 19124: 19044: 19014: 19009: 18854: 18826: 18821: 18791: 18776: 18766: 18746: 18741: 18701: 18666: 18656: 18611: 18591: 18576: 18571: 18541: 18486: 18481: 18476: 18421: 18396: 18381: 18356: 18346: 18336: 18331: 18245: 18240: 18235: 18220: 18160: 18155: 18130: 17989: 17979: 17959: 17919: 17914: 17889: 17874: 17839: 17834: 17734: 17709: 17603: 17598: 17588: 17578: 17568: 17503: 17433: 17390: 17234: 17164: 17134: 17119: 17104: 17077: 17042: 17027: 17012: 16997: 16962: 16952: 16922: 16907: 16882: 16847: 16842: 16832: 16822: 16782: 16777: 16737: 16727: 16662: 16647: 16622: 16582: 16567: 16557: 16346: 16336: 16281: 16252: 16202: 16146: 16099: 16081: 16016: 15996: 15945: 15935: 15910: 15870: 15865: 15810: 15780: 15759: 15749: 15739: 15638: 15618: 15608: 15588: 15568: 15528: 15518: 15465: 15394: 15376: 15348: 15333: 15292: 15272: 15221: 15211: 15186: 15146: 15141: 15086: 15056: 15035: 15025: 15010: 14939: 14904: 14833: 14823: 14813: 14808: 14756: 14736: 14726: 14701: 14681: 14611: 14586: 14561: 14556: 14551: 14516: 14511: 14469: 14464: 14413: 14221: 13636: 13590: 13467: 13462: 13457: 13382: 13367: 13362: 13317: 13296: 13288: 13200: 13195: 13180: 13165: 13100: 13045: 12621: 12611: 12606: 12601: 12581: 12566: 12556: 12536: 12438: 12421: 12411: 12401: 12391: 12386: 12356: 12331: 12326: 12306: 12291: 12256: 12241: 12204: 12139: 12099: 12089: 11946: 11941: 11926: 11911: 11851: 11716: 11620: 11615: 11610: 11600: 11595: 11476: 11423: 11418: 11403: 11246: 11221: 11211: 11201: 11191: 11181: 11096: 11091: 11081: 10994: 10574: 10438: 10272: 10220: 10205: 9863: 9848: 9828: 9798: 9728: 9612: 9592: 9582: 9577: 9557: 9518: 9468: 9463: 9448: 9438: 9403: 9353: 9323: 9318: 9308: 9228: 9171: 9124: 9056: 9031: 8979: 8894: 8780: 8718: 8695: 8403: 8388: 8334: 8322: 8136: 8111: 7999: 7974: 7690: 7587: 7452: 7387: 7382: 7372: 7329: 7314: 7299: 7289: 7259: 7249: 7122: 7092: 7087: 7033: 7010: 7005: 6977: 6911: 6901: 6843: 6749: 6613: 6598: 6593: 6578: 6499: 6434: 6376: 4319: 2323: 2158: 2101: 1343: 1073: 103: 6053:"Sun Pharma Q1 2011-12 Earnings Call Transcript 10.00 am, July 29, 2011" 5793: 5708: 5569: 4727: 3974: 2809:"Atomoxetine Hydrochloride capsule [Mylan Pharmaceuticals Inc.]" 2389: 510: 30: 19617: 19587: 19562: 19443: 19354: 19334: 19311: 19154: 19129: 19119: 19074: 19064: 19049: 18964: 18858: 18786: 18781: 18756: 18726: 18716: 18691: 18676: 18651: 18621: 18596: 18586: 18546: 18526: 18516: 18496: 18426: 18411: 18230: 18210: 18205: 18180: 18110: 18049: 18029: 17984: 17974: 17969: 17909: 17899: 17829: 17744: 17593: 17583: 17573: 17563: 17528: 17518: 17483: 17453: 17443: 17438: 17375: 17219: 17194: 17189: 17184: 17174: 17159: 17129: 17047: 17037: 17032: 16982: 16937: 16917: 16887: 16837: 16817: 16772: 16697: 16587: 16577: 16395: 16351: 16316: 16243: 16206: 16166: 16136: 16113: 16077: 16026: 16011: 15895: 15880: 15850: 15840: 15835: 15790: 15785: 15724: 15719: 15704: 15678: 15648: 15643: 15628: 15623: 15598: 15593: 15563: 15558: 15538: 15533: 15457: 15436: 15419: 15414: 15297: 15287: 15171: 15156: 15126: 15116: 15111: 15066: 15061: 14995: 14990: 14949: 14929: 14914: 14889: 14873: 14848: 14843: 14721: 14711: 14696: 14641: 14631: 14621: 14601: 14591: 14576: 14571: 14494: 14484: 14479: 14292: 14185: 14180: 13940: 13868: 13863: 13799: 13794: 13784: 13779: 13759: 13580: 13569: 13565: 13532: 13417: 13412: 13387: 13377: 13352: 13347: 13342: 13283: 13273: 13255: 13250: 13220: 13210: 13170: 13135: 13090: 13080: 13075: 13070: 13055: 13020: 12945: 12889: 12866: 12834: 12761: 12721: 12679: 12669: 12644: 12616: 12576: 12561: 12481: 12476: 12416: 12396: 12381: 12371: 12236: 12226: 12154: 12149: 12144: 12134: 12094: 12049: 12044: 11956: 11936: 11876: 11866: 11796: 11776: 11761: 11751: 11741: 11726: 11711: 11701: 11691: 11681: 11640: 11635: 11630: 11605: 11585: 11565: 11491: 11481: 11466: 11456: 11408: 11356: 11291: 11216: 11206: 11196: 11176: 11151: 11146: 11126: 11106: 11076: 10916: 10656: 10557: 10552: 10507: 10502: 10497: 10416: 10411: 10354: 10349: 10344: 10200: 10180: 9901: 9873: 9823: 9808: 9785: 9780: 9775: 9708: 9678: 9668: 9607: 9543: 9528: 9508: 9453: 9423: 9408: 9383: 9368: 9333: 9328: 9288: 9283: 9253: 9238: 9198: 9176: 9139: 9109: 9094: 9074: 8832: 8802: 8785: 8775: 8530: 8520: 8495: 8450: 8327: 8312: 8307: 8287: 8246: 8236: 8226: 8206: 8201: 8161: 8156: 8116: 8106: 8091: 8031: 8006: 7808: 7794: 7780: 7686: 7682: 7678: 7632: 7602: 7597: 7592: 7572: 7542: 7532: 7492: 7477: 7457: 7344: 7324: 7294: 7274: 7254: 7214: 7162: 7147: 7142: 7102: 7066: 7038: 6967: 6944: 6939: 6891: 6863: 6858: 6853: 6838: 6828: 6629: 6608: 6588: 6583: 6545: 6514: 6491: 6426: 5917: 5619: 5079: 5040:"21-411 Strattera Clinical Pharmacology Biopharmaceutics Review Part 2" 4516: 3323: 1351: 1317: 1236: 1232: 1160: 1040:(TBI). It is used with the goal of treating ADHD-like symptoms such as 980: 890: 862: 752: 529: 188: 6275: 4683: 2938: 932:
for the treatment of attention deficit hyperactivity disorder (ADHD).
905:, and aggression. There is a lack of data regarding its safety during 19572: 19567: 19517: 19489: 19418: 19379: 19374: 19349: 19344: 19271: 19179: 19169: 19059: 18969: 18883: 18841: 18831: 18771: 18761: 18751: 18721: 18711: 18706: 18661: 18631: 18511: 18491: 18391: 18386: 18341: 18260: 18255: 18215: 18200: 18175: 18105: 18044: 18014: 17964: 17954: 17949: 17814: 17704: 17669: 17664: 17608: 17533: 17513: 17508: 17478: 17408: 17370: 17350: 17345: 17285: 17269: 17259: 17204: 17114: 17062: 17057: 16992: 16947: 16927: 16807: 16797: 16642: 16383: 16331: 16301: 16296: 16216: 16198: 16194: 16151: 16109: 16052: 16001: 15920: 15890: 15754: 15673: 15663: 15658: 15653: 15578: 15573: 15453: 15449: 15338: 15328: 15277: 15196: 15166: 15030: 14980: 14899: 14894: 14863: 14858: 14818: 14716: 14706: 14671: 14596: 14566: 14499: 14459: 14423: 14328: 14313: 14287: 14251: 14241: 14170: 14165: 14160: 14155: 13960: 13906: 13822: 13705: 13695: 13626: 13555: 13517: 13492: 13482: 13407: 13357: 13302: 13278: 13205: 13115: 13110: 13105: 13065: 13060: 13050: 13035: 12894: 12766: 12746: 12726: 12716: 12674: 12654: 12571: 12366: 12281: 12271: 12251: 12189: 12174: 12164: 12124: 12109: 12079: 12064: 12059: 12054: 11980: 11921: 11871: 11861: 11856: 11841: 11831: 11811: 11801: 11781: 11756: 11386: 11351: 11331: 11296: 11286: 11251: 11236: 10901: 10815: 10802: 10725: 10634: 10621: 10579: 10487: 10482: 10443: 10334: 10329: 10158: 10133: 10044: 10039: 10024: 9698: 9688: 9646: 9572: 9562: 9488: 9483: 9443: 9418: 9413: 9363: 9338: 9268: 9243: 9233: 9208: 9203: 9193: 9069: 8954: 8939: 8919: 8904: 8899: 8790: 8615: 8610: 8556: 8445: 8440: 8435: 8393: 8302: 8297: 8272: 8181: 8121: 8101: 8096: 8086: 8076: 8051: 7979: 7941:
Tooltip α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
7696: 7582: 7517: 7512: 7487: 7482: 7472: 7467: 7377: 7319: 7284: 7264: 7229: 7185: 7043: 7000: 6972: 6906: 6848: 6707: 6573: 6568: 6540: 6509: 6304: 3401: 2447: 2442:
The drug was originally known as tomoxetine. It was renamed to avoid
2080: 1355: 1228: 1184: 1168: 1041: 984: 929: 906: 898: 448: 374: 89: 7021: 6874: 4857: 4840: 19577: 19369: 19114: 19024: 19004: 18994: 18949: 18878: 18671: 18581: 18566: 18531: 18521: 18401: 18225: 18120: 18095: 18034: 18019: 17929: 17849: 17819: 17799: 17769: 17714: 17694: 17659: 17548: 17473: 17458: 17380: 17360: 17229: 17224: 17209: 17179: 17149: 17109: 16977: 16867: 16812: 16722: 16657: 16627: 16512: 16370: 16321: 16311: 16210: 16156: 16117: 16095: 15885: 15875: 15668: 15461: 15404: 15390: 15161: 15151: 14853: 14838: 14803: 14661: 14656: 14646: 14616: 14418: 14175: 13631: 13437: 13432: 13392: 13307: 13155: 13030: 12968: 12351: 12316: 12221: 11836: 11766: 11736: 11696: 11590: 11381: 11341: 11321: 10867: 10567: 10426: 10230: 10225: 10059: 9843: 9641: 9548: 9373: 9358: 9273: 9188: 9104: 8994: 8876: 8807: 8797: 8659: 8525: 8423: 8231: 7860: 7447: 7403: 7127: 7112: 6955: 6671: 6166:
Molecular Neuropharmacology: A Foundation for Clinical Neuroscience
6031:"Sun Pharma receives USFDA approval for generic Strattera capsules" 5945:(8th ed.). Foster City, CA: Biomedical Publications. pp.  2998: 2089: 2045: 2041: 1359: 1347: 1176: 1148: 602: 594: 501: 131: 5213: 4130:
Journal of the American Academy of Child and Adolescent Psychiatry
4081:
Journal of the American Academy of Child and Adolescent Psychiatry
3047:
Journal of the American Academy of Child and Adolescent Psychiatry
1394: 775: 19542: 19423: 19301: 18984: 18868: 18646: 18636: 17864: 17794: 17729: 17679: 17538: 17290: 17264: 17254: 17239: 17144: 16957: 16932: 16682: 16562: 16176: 16006: 15959: 15955: 15905: 15900: 15855: 15845: 15805: 15734: 15613: 15282: 15235: 15231: 15181: 15176: 15131: 15121: 15081: 15005: 14924: 14686: 14676: 14666: 14636: 14581: 14403: 14398: 14393: 14388: 14383: 14378: 14373: 14333: 14231: 14150: 13700: 13522: 13322: 12847: 12246: 12184: 11846: 11826: 11522: 11393: 10257: 10252: 10237: 10074: 9887: 9733: 9723: 9703: 9658: 9144: 8759: 8744: 8710: 8644: 8535: 8413: 8131: 8061: 8041: 7989: 7269: 5898: 2147: 1339: 1313: 1172: 1045: 944:
treatments for ADHD is that it has little known abuse potential.
902: 6408: 6080:"FDA approves first generic Strattera for the treatment of ADHD" 5463: 5293:
Koda K, Ago Y, Cong Y, Kita Y, Takuma K, Matsuda T (July 2010).
4208: 3089: 1279:
agents, due to atomoxetine acting as an indirect sympathomimetic
19552: 19537: 19532: 19403: 19296: 18959: 18626: 18441: 18100: 18024: 18009: 17999: 17774: 17365: 17244: 16862: 16742: 16186: 15915: 15860: 15603: 15441: 15191: 15136: 14944: 14691: 14368: 13526: 12790:
Tooltip G protein-coupled inwardly rectifying potassium channel
12639: 12635:
Tooltip G protein-coupled inwardly rectifying potassium channel
12311: 12231: 12114: 12104: 11886: 11655: 10860: 10797: 10477: 10472: 10431: 10324: 10319: 9763: 9663: 9036: 8767: 8749: 8726: 8021: 8016: 6993:
Tooltip Noradrenergic and specific serotonergic antidepressants
6816: 4172: 3958:"A critical appraisal of atomoxetine in the management of ADHD" 3259: 3004: 2483: 2423: 2316:-desmethylatomoxetine and 2-hydroxymethylatomoxetine and their 2301: 2297: 2286: 2220: 2132: 1224: 1164: 894: 641: 379: 354: 9974: 19557: 19159: 19054: 18796: 18551: 18416: 17789: 17739: 17699: 17463: 17154: 17098: 17007: 16692: 16687: 14006: 12496: 12266: 12119: 10906: 10835: 10807: 10730: 10639: 10626: 10547: 10537: 10406: 10396: 10195: 10138: 9758: 9183: 8974: 8700: 8510: 8036: 8026: 7184: 6341:. In Pratt VM, McLeod HL, Rubinstein WS, et al. (eds.). 6231: 5172: 5116: 4487: 4123: 4074: 3573:(76 ed.). Pharmaceutical Press. 2018. pp. 344–345. 3040: 2067:(SERT) inhibitor at clinical doses in humans is uncertain. A 909:; as of 2019, its safety during pregnancy and for use during 766: 613: 350: 16498: 12914: 7923: 5601: 4665: 4412:"Concentration deficit disorder (sluggish cognitive tempo)." 2033:(DAT) expression is minimal. In rats, atomoxetine increased 1338:, atomoxetine does not affect the plasma protein binding of 674: 18561: 16260: 13842:
Tooltip Cystic fibrosis transmembrane conductance regulator
13764: 12809: 12467: 12429: 12212: 10896: 10542: 10401: 10267: 10190: 10128: 10014: 9651: 9478: 9064: 9051: 8685: 8505: 8475: 8465: 8378: 8211: 8176: 8166: 7964: 7054: 6163: 5333: 4546: 4301: 3223: 2143: 2136: 2116: 1995: 1251: 1247: 935: 585: 14782: 13738: 11043: 6922: 5254: 3347: 10878: 10779: 10707: 10603: 10454: 10296: 10110: 9996: 8889: 6115:"Atomoxetine: a novel treatment for child and adult ADHD" 5384:
The Journal of Pharmacology and Experimental Therapeutics
4984: 4762:"Atomoxetine and suicidality in children and adolescents" 4490:"On the pathophysiology and treatment of akinetic mutism" 3141: 2541: 2418:
salt (atomoxetine HCl) under the brand name Strattera by
2079:
studies have failed to find an increase in extracellular
16231: 12008: 5411: 5248: 4794: 3732: 3308: 12699: 12519: 5778: 5690: 3507: 3445: 2976:"Atomoxetine Hydrochloride Monograph for Professionals" 2250:-acid glycoprotein (77%) and IgG (15%). Its metabolite 1227:. Concurrent treatment with a CYP2D6 inhibitor such as 991:
adolescents over 70 kg and adults is 100 mg.
15773:
Serotonin–norepinephrine–dopamine reuptake inhibitors:
15049:
Serotonin–norepinephrine–dopamine reuptake inhibitors:
9181:
Uncompetitive pore blockers (mostly dizocilpine site):
6164:
Malenka RC, Nestler EJ, Hyman SE, Holtzman DM (2015).
5550: 3864: 3348:
Hanwella R, Senanayake M, de Silva V (November 2011).
19635: 15492: 12996: 8587: 4935: 4350: 2632: 2630: 2628: 2626: 2624: 2622: 14129: 7026:
Tooltip Serotonin antagonist and reuptake inhibitors
6879:
Tooltip Serotonin–norepinephrine reuptake inhibitors
6738:
Serotonin-norepinephrine-dopamine reuptake inhibitor
4838: 2774:. Eli Lilly Australia Pty. Limited. 21 August 2013. 19673:
Attention deficit hyperactivity disorder management
7360: 6960:
Tooltip Norepinephrine–dopamine reuptake inhibitors
6657:
Attention deficit hyperactivity disorder management
6005:"Lilly loses ADD patent case, cuts revenue outlook" 5865: 4584: 2526: 999: 489: 14771: 5938: 5870:. Berlin, Heidelberg: Springer. pp. 158–160. 4884: 4215:Journal of Child and Adolescent Psychopharmacology 4176:Journal of Child and Adolescent Psychopharmacology 3598:"Atomoxetine Pregnancy and Breastfeeding Warnings" 3148:Journal of Child and Adolescent Psychopharmacology 3096:Journal of Child and Adolescent Psychopharmacology 3008:Journal of Child and Adolescent Psychopharmacology 2619: 2496: 2393:Original synthesis of atomoxetine, as patented by 1432: 1028:Atomoxetine is sometimes used in the treatment of 411:-Methyl-3-(2-methylphenoxy)-3-phenylpropan-1-amine 14108: 14031: 13605: 7880: 7202: 6235:Autism Spectrum Disorder Parents Medication Guide 5381: 4845:Journal of Pharmacy & Pharmaceutical Sciences 4351:Barkley RA, DuPaul GJ, McMurray MB (April 1991). 4009:The Maudsley prescribing guidelines in psychiatry 4006: 2982:. American Society of Health-System Pharmacists. 2400: 1257:of 6.3 μM, which has the potential to cause 19659: 19620:(met-enkephalin releaser/degradation stabilizer) 13669: 7425: 5822: 5679: 5544: 5506: 5454: 5402: 5327: 5283: 5159: 4978: 4929: 4873: 4832: 3762: 3343: 3341: 2913: 2876: 2675:List of nationally authorised medicinal products 469: 461: 14069:Transient receptor potential channel modulators 7762: 6821:Tooltip Selective serotonin reuptake inhibitors 6188: 6168:(3rd ed.). New York: McGraw-Hill Medical. 5941:Disposition of Toxic Drugs and Chemicals in Man 5691:Kobayashi T, Washiyama K, Ikeda K (June 2010). 5686: 5684: 5682: 5459: 5457: 5407: 5405: 5292: 5288: 5286: 5168: 5166: 5164: 5162: 4880: 4878: 4876: 4585:Dougall D, Poole N, Agrawal N (December 2015). 4483: 4481: 4445: 4443: 3951: 3949: 3899: 3897: 3828: 3408:Medical Journal of the Islamic Republic of Iran 2920: 2918: 2916: 2478:Atomoxetine may be used in those with ADHD and 2475:, particularly in cases with concomitant ADHD. 1246:Atomoxetine has been found to directly inhibit 436: 428: 16476: 8839: 8824: 6488: 6419: 3441: 3439: 3397: 3395: 2638:"Strattera- atomoxetine hydrochloride capsule" 2504:"Atomoxetine (Strattera) Use During Pregnancy" 16462: 15697:Serotonin–norepinephrine reuptake inhibitors: 15481: 14973:Serotonin–norepinephrine reuptake inhibitors: 14801:Selective norepinephrine reuptake inhibitors: 14094: 14011:Tooltip Transient receptor potential channels 12501:Tooltip Inwardly rectifying potassium channel 11010: 9960: 7909: 6765: 6392: 6349:National Center for Biotechnology Information 5650: 4257: 3503: 3501: 3338: 2379:Strattera 60-mg capsule front with Lilly logo 1403: 19718:Serotonin–norepinephrine reuptake inhibitors 14887:Norepinephrine–dopamine reuptake inhibitors: 14118: 12919:Tooltip Tandem pore domain potassium channel 5176:Bioorganic & Medicinal Chemistry Letters 4623: 4578: 4540: 4478: 4440: 4025: 3946: 3894: 3625: 3623: 1389: 1267:medications that may prolong the QT interval 135: 12817:Tooltip Calcium-activated potassium channel 7796: 7613: 7553: 7059:Tooltip Serotonin modulator and stimulators 6726:Serotonin-norepinephrine reuptake inhibitor 4722:(Plain English summary). 1 September 2020. 4591:The Cochrane Database of Systematic Reviews 4031: 3903: 3858: 3592: 3590: 3436: 3392: 2970: 2968: 2966: 2964: 2962: 2960: 2958: 2956: 2924: 2815:. Mylan Pharmaceuticals Inc. October 2011. 2463:version was approved in the United States. 2327:Major metabolites of atomoxetine in humans. 2266:-desmethylatomoxetine averaged 33.3 hours. 2127:, suggesting a glutaminergic mechanism. In 860:selective norepinephrine reuptake inhibitor 194:Selective norepinephrine reuptake inhibitor 16469: 16455: 14787:Tooltip Norepinephrine reuptake inhibitors 14101: 14087: 13743:Tooltip Calcium-activated chloride channel 12035:4-Aminopyridine (fampridine/dalfampridine) 11048:Tooltip Voltage-dependent calcium channels 11024: 11017: 11003: 9967: 9953: 9926:Metabotropic glutamate receptor modulators 7916: 7902: 6927:Tooltip Norepinephrine reuptake inhibitors 6779: 6772: 6758: 6732:Norepinephrine-dopamine reuptake inhibitor 6406: 6399: 6385: 5963: 5209: 5207: 5205: 5092:Psychoactive Drug Screening Program (PDSP) 3774:National Institute of Mental Health (NIMH) 3770:"Attention Deficit Hyperactivity Disorder" 3498: 2872: 2870: 2868: 2866: 2864: 2862: 2860: 2858: 2856: 2854: 2644:. Eli Lilly and Company. 29 January 2020. 2285:are expected to vary based on a patient's 711: 688: 545: 537: 10979:Glutamate metabolism/transport modulators 10886:Tooltip Metabotropic glutamate receptor 8 10787:Tooltip Metabotropic glutamate receptor 7 10715:Tooltip Metabotropic glutamate receptor 6 10611:Tooltip Metabotropic glutamate receptor 4 10462:Tooltip Metabotropic glutamate receptor 3 10304:Tooltip Metabotropic glutamate receptor 2 10118:Tooltip Metabotropic glutamate receptor 5 10004:Tooltip Metabotropic glutamate receptor 1 9933:Glutamate metabolism/transport modulators 6339:"Atomoxetine Therapy and CYP2D6 Genotype" 6140: 6130: 6112: 6074: 6072: 5774: 5772: 5716: 5627: 5578: 5568: 5437: 5310: 5231: 5142: 5010: 4953: 4912: 4902: 4856: 4691: 4659: 4629: 4606: 4515: 4505: 4452:The Journal of Head Trauma Rehabilitation 4327: 4234: 4149: 4100: 3983: 3973: 3962:Therapeutics and Clinical Risk Management 3955: 3921: 3822: 3792: 3620: 3419: 3375: 3365: 3285: 3167: 3137: 3135: 3115: 3066: 2852: 2850: 2848: 2846: 2844: 2842: 2840: 2838: 2836: 2834: 1537: 1508: 1481: 1272:Other notable drug interactions include: 1023: 573: 565: 19678:Drugs developed by Eli Lilly and Company 16236:Tooltip Vesicular monoamine transporters 15511:Selective serotonin reuptake inhibitors: 12013:Tooltip Voltage-gated potassium channels 10975:Ionotropic glutamate receptor modulators 8345: 7654: 6651:Attention deficit hyperactivity disorder 5034: 5032: 5030: 4000: 3587: 3571:British national formulary : BNF 76 3565: 3563: 2953: 2388: 2322: 2095:Atomoxetine has been found to act as an 1300:Direct-acting sympathomimetics, such as 936:Attention deficit hyperactivity disorder 867:attention deficit hyperactivity disorder 12707:Tooltip ATP-sensitive potassium channel 12527:Tooltip ATP-sensitive potassium channel 5971:"Patent and Exclusivity Search Results" 5202: 5078: 4885:Kasi PM, Mounzer R, Gleeson GH (2011). 4421:. The Guilford Press. pp. 81–115. 4409: 2768:"Strattera (atomoxetine hydrochloride)" 2258:the half-life of the active metabolite 684: 517: 509: 108: 19660: 9656:Alcohols/volatile anesthetics/related: 6720:Selective serotonin reuptake inhibitor 6119:Neuropsychiatric Disease and Treatment 6069: 5936: 5769: 4798:Journal of Clinical Psychopharmacology 4772:(5): 166. October 2013. Archived from 4494:Neuroscience and Biobehavioral Reviews 4449: 3266:Neuroscience and Biobehavioral Reviews 3227:Neuroscience and Biobehavioral Reviews 3132: 2831: 2762: 2760: 2561: 2437: 1088:Any cardiovascular disease including: 702: 304: 276: 16450: 15497:Tooltip Serotonin reuptake inhibitors 14082: 13001:Tooltip Voltage-gated sodium channels 10998: 9948: 8812:Other positive allosteric modulators: 8592:Tooltip N-Methyl-D-aspartate receptor 7897: 7879: 7864: 7749: 7653: 7424: 7183: 6796: 6753: 6380: 5027: 4391:from the original on 28 February 2024 3780:from the original on 25 December 2016 3704:"Atomoxetine - Drug Usage Statistics" 3629: 3560: 3486:from the original on 15 November 2023 2819:from the original on 10 November 2013 2758: 2756: 2754: 2752: 2750: 2748: 2746: 2744: 2742: 2740: 2725:from the original on 10 November 2013 2709: 2707: 2705: 2703: 2701: 2699: 2142:Atomoxetine also reversibly inhibits 2025:Atomoxetine inhibits the presynaptic 1010:randomised controlled clinical trials 873:. It may be used alone or along with 657: 649: 629: 621: 289: 126: 94: 14134:Tooltip Dopamine reuptake inhibitors 12936:12-O-Tetradecanoylphorbol-13-acetate 7865: 6363:from the original on 26 October 2020 6336: 6248:from the original on 11 April 2017. 6157: 5997: 5757:from the original on 18 October 2023 5557:Drug Design, Development and Therapy 5072: 4742:from the original on 21 January 2022 4549:International Review of Neurobiology 4428:from the original on 16 January 2024 4007:Taylor D, Paton C, Shitij K (2012). 3684:from the original on 15 January 2024 3202:from the original on 2 February 2017 2803: 2801: 2799: 2797: 2795: 2793: 2577:from the original on 19 October 2023 1079: 212: 12030:3,4-Diaminopyridine (amifampridine) 10518:Pomaglumetad methionil (LY-2140023) 10370:Pomaglumetad methionil (LY-2140023) 9553:Ifenprodil (NR2B) site antagonists: 7365:Tooltip Tetracyclic antidepressants 6662:Hypokalemic sensory overstimulation 5098:from the original on 27 August 2021 3880:10.1001/archgenpsychiatry.2011.2053 3714:from the original on 7 October 2021 2677:. European Medicines Agency. 2016. 2607:from the original on 8 October 2021 2446:, as the name may be confused with 2331: 2214: 1384: 1370: 601: 593: 452: 13: 15831:Didesmethylsibutramine (BTS-54505) 15107:Didesmethylsibutramine (BTS-54505) 14776:Tooltip Norepinephrine transporter 14537:Didesmethylsibutramine (BTS-54505) 8117:Pesampator (BIIB-104, PF-04958242) 6329: 5985:from the original on 22 March 2012 5868:Encyclopedia of Psychopharmacology 4810:10.1097/01.jcp.0000104907.75206.c2 4561:10.1016/B978-0-12-411546-0.00015-9 4308:The Journal of Clinical Psychiatry 3904:Bushe CJ, Savill NC (March 2014). 3608:from the original on 22 March 2019 2737: 2696: 2668:"Active substance(s): atomoxetine" 2514:from the original on 22 March 2019 1437:Tooltip Norepinephrine transporter 1292:norepinephrine reuptake inhibitors 1154: 14: 19734: 18437:Desmetramadol (desmethyltramadol) 17765:Desmetramadol (desmethyltramadol) 16718:Dextropropoxyphene (propoxyphene) 16703:Desmetramadol (desmethyltramadol) 14349:Etybenzatropine (ethybenztropine) 14036:Tooltip Ligand gated ion channels 13610:Tooltip Epithelial sodium channel 7750: 7207:Tooltip Tricyclic antidepressants 6702:Norepinephrine reuptake inhibitor 6191:Expert Opinion on Pharmacotherapy 5665:10.2174/1381612819666140110115227 5060:from the original on 1 March 2017 3810:from the original on 6 April 2019 3192:"Parent's Medication Guide: ADHD" 2986:from the original on 4 April 2019 2790: 2778:from the original on 6 April 2017 2684:from the original on 12 June 2022 1044:problems, disinhibition, lack of 1004:Atomoxetine may be used to treat 239: 158: 19645: 18817:Salvinorin B methoxymethyl ether 15821:Desmethylsibutramine (BTS-54354) 15097:Desmethylsibutramine (BTS-54354) 14527:Desmethylsibutramine (BTS-54354) 13674:Tooltip Acid-sensing ion channel 6094:from the original on 4 June 2017 5837:10.2165/00003088-200544060-00002 5430:10.1111/j.1476-5381.2010.00707.x 5349:10.1016/j.neuroimage.2013.08.001 5312:10.1111/j.1471-4159.2010.06750.x 5269:10.2165/11599630-000000000-00000 5003:10.1111/j.1476-5381.2008.00018.x 4942:Journal of Clinical Pharmacology 4464:10.1097/00001199-200601000-00010 4011:. West Sussex: Wiley-Blackwell. 3844:10.1111/j.1471-4159.2010.06750.x 3548:from the original on 23 May 2023 3196:American Psychiatric Association 2891:10.2165/00003088-200544060-00002 2648:from the original on 7 June 2018 2372: 2360: 2113:-adrenergic receptor antagonists 2040:concentrations without altering 1058:cognitive disengagement syndrome 1036:symptoms due to conditions like 1006:cognitive disengagement syndrome 1000:Cognitive disengagement syndrome 871:cognitive disengagement syndrome 869:(ADHD) and, to a lesser extent, 798:CC1=C(C=CC=C1)O(CCNC)C2=CC=CC=C2 742: 736: 58: 38: 29: 18812:Salvinorin B ethoxymethyl ether 16432:Monoamine metabolism modulators 10914:Positive allosteric modulators: 10865:Negative allosteric modulators: 10654:Positive allosteric modulators: 10572:Negative allosteric modulators: 10436:Negative allosteric modulators: 10379:Positive allosteric modulators: 10235:Negative allosteric modulators: 10178:Positive allosteric modulators: 9976:Metabotropic glutamate receptor 9593:Rislenemdaz (CERC-301, MK-0657) 8540:Negative allosteric modulators: 8428:Positive allosteric modulators: 8251:Negative allosteric modulators: 8004:Positive allosteric modulators: 6298: 6255: 6225: 6182: 6106: 6045: 6023: 5930: 5911: 5892: 5859: 5816: 5782:Drug Metabolism and Disposition 5733: 5644: 5595: 5500: 5418:British Journal of Pharmacology 5375: 5129:(2). Springer Nature: 189–200. 4991:British Journal of Pharmacology 4788: 4754: 4708: 4507:10.1016/j.neubiorev.2020.02.006 4403: 4344: 4295: 4251: 4202: 4166: 4117: 4068: 3726: 3696: 3666: 3302: 3278:10.1016/j.neubiorev.2021.01.022 3253: 3239:10.1016/j.neubiorev.2024.105703 3217: 3184: 3083: 3034: 2573:(published 18 September 2023). 2125:-adrenergic receptor antagonist 1988: 1983: 1964: 1959: 1940: 1935: 1764: 1759: 1741: 1736: 1699: 1694: 1676: 1671: 1653: 1648: 1626: 1621: 1579: 1574: 1556: 1528: 1517: 1500: 1472: 1467: 1423: 1365: 1214: 1130:Severe cardiovascular disorders 923: 823:Key:VHGCDTVCOLNTBX-QGZVFWFLSA-N 19688:Mu-opioid receptor antagonists 19683:Kappa-opioid receptor agonists 18737:Norbuprenorphine-3-glucuronide 11492:Ziconotide (ω-conotoxin MVIIA) 8829:Tooltip Dehydroepiandrosterone 8137:Tulrampator (S-47445, CX-1632) 8032:Farampator (CX-691, ORG-24448) 6424:Tooltip central nervous system 6090:(Press release). 30 May 2017. 5478:10.1016/j.brainres.2017.01.028 4599:10.1002/14651858.CD009221.pub2 4261:Journal of Attention Disorders 3868:Archives of General Psychiatry 3736:Journal of Affective Disorders 3452:Journal of Attention Disorders 2715:"Atomoxetine (Rx) – Strattera" 2660: 2589: 2555: 2453: 2401:Detection in biological fluids 2189:stimulation, as well as other 2115:, but could be potentiated by 2092:(a marker of NET inhibition). 1376:Atomoxetine (and metabolites) 745: 730: 265: 252: 1: 18712:Nalodeine (N-allylnorcodeine) 17905:Met-enkephalin (metenkefalin) 17514:Nalodeine (N-allylnorcodeine) 16943:Met-enkephalin (metenkefalin) 16412:Receptor/signaling modulators 15486:Tooltip Serotonin transporter 14110:Monoamine reuptake inhibitors 14065:Receptor/signaling modulators 11467:Leconotide (ω-conotoxin CVID) 10971:Receptor/signaling modulators 9919:Receptor/signaling modulators 9768:Unknown/unsorted antagonists: 8332:Unknown/unsorted antagonists: 7925:Ionotropic glutamate receptor 6203:10.1517/14656566.2015.1079620 6113:Ledbetter M (December 2006). 5919:B1 US patent EP0052492 B1 5653:Current Pharmaceutical Design 5233:10.1016/S0893-133X(02)00346-9 4034:Journal of Psychopharmacology 3910:Journal of Psychopharmacology 3514:Journal of Psychopharmacology 2489: 2351:Atomoxetine, or (−)-methyl[(3 2203:, acting as an antagonist at 2019:oocytes. Additional sources: 1408:Tooltip Serotonin transporter 994: 261:(Other controlled substances) 16:Medication used to treat ADHD 19723:Wakefulness-promoting agents 17935:N-Phenethyl-14-ethoxymetopon 15326:Tetracyclic antidepressants: 14123:Tooltip Dopamine transporter 7427:Monoamine oxidase inhibitors 6307:Archives of Iranian Medicine 6086:Food and Drug Administration 6035:International Business Times 5979:Food and Drug Administration 5876:10.1007/978-3-540-68706-1_35 5049:Food and Drug Administration 4645:10.1097/WNF.0b013e3181dca948 2384: 2367:Strattera 60-mg capsule back 2346: 2272:trough plasma concentrations 1196:Food and Drug Administration 1143:monoamine oxidase inhibitors 1133:Uncontrolled hyperthyroidism 854:, sold under the brand name 7: 19588:β-Lipotropin (proendorphin) 19216:((pF)Phe)Nociceptin(1-13)NH 18597:Leumorphin (dynorphin B-29) 17083:Oxymorphone phenylhydrazone 15776:3,3-Diphenylcyclobutanamine 15052:3,3-Diphenylcyclobutanamine 9617:NR2A-selective antagonists: 9149:Polyamine site antagonists: 8374:Acromelic acid (acromelate) 7960:Acromelic acid (acromelate) 7621:Tooltip Monoamine oxidase B 7561:Tooltip Monoamine oxidase A 7190:tetracyclic antidepressants 6684:Dopamine reuptake inhibitor 6359:. Bookshelf ID: NBK315951. 3800:"Mental Health Medications" 2466: 2058:dopamine reuptake inhibitor 1250:potassium currents with an 1206: 1141:Concomitant treatment with 1084:Contraindications include: 10: 19739: 19708:Potassium channel blockers 19608:Proopiomelanocortin (POMC) 19228:-NH)Gly)Nociceptin(1-13)NH 18332:Adrenorphin (metorphamide) 17499:Methylsamidorphan chloride 16733:Dimethylaminopivalophenone 16558:Adrenorphin (metorphamide) 16416:Monoamine releasing agents 15974:Tricyclic antidepressants: 15250:Tricyclic antidepressants: 14319:Benzatropine (benztropine) 13028:Antiarrhythmics (class I): 8057:Hydrochlorothiazide (HCTZ) 7098:Dextromethorphan/bupropion 6696:Norepinephrine transporter 6344:Medical Genetics Summaries 5188:10.1016/j.bmcl.2004.05.018 4955:10.1177/009127002762491307 4633:Clinical Neuropharmacology 4142:10.1016/j.jaac.2022.07.821 4093:10.1016/j.jaac.2022.07.821 3059:10.1016/j.jaac.2022.07.821 2409: 2223:activity, resulting in an 2063:Atomoxetine's status as a 2027:norepinephrine transporter 1056:, including symptoms from 720:Chemical and physical data 19693:NMDA receptor antagonists 19528:Racecadotril (acetorphan) 19476: 19388: 19203: 19192: 18935:Buprenorphine/samidorphan 18892: 18847:Tricyclic antidepressants 18289: 18278: 18058: 17925:Mitragynine pseudoindoxyl 17632: 17621: 17278: 16968:Mitragynine pseudoindoxyl 16487: 16404: 16360: 16229: 16040: 15969: 15768: 15692: 15506: 15479: 15357: 15321: 15245: 15044: 14968: 14882: 14796: 14769: 14452: 14306: 14270: 14194: 14143: 14116: 14058: 14029: 14004: 13997: 13931: 13924: 13877: 13849: 13835: 13813: 13750: 13736: 13727: 13681: 13667: 13645: 13617: 13603: 13546: 13538:Tricyclic antidepressants 13008: 12994: 12985: 12959: 12926: 12912: 12856: 12824: 12807: 12688: 12547:Glibenclamide (glyburide) 12508: 12494: 12457: 12020: 12006: 11997: 11965: 11055: 11032: 10964: 10876: 10777: 10705: 10601: 10592: 10503:LY-404,039 (pomaglumetad) 10452: 10350:LY-404,039 (pomaglumetad) 10294: 10285: 10108: 9994: 9985: 9910: 8999:Glycine site antagonists: 8585: 8343: 7934: 7891: 7873: 7821: 7756: 7745: 7662: 7649: 7611: 7551: 7437: 7433: 7420: 7396: 7358: 7200: 7196: 7179: 7080: 7052: 7019: 6986: 6953: 6920: 6872: 6814: 6810: 6792: 6667:Monoamine releasing agent 6643: 6622: 6554: 6523: 6485: 6417: 6132:10.2147/nedt.2006.2.4.455 5900:A US patent 4018895 A 5825:Clinical Pharmacokinetics 5522:10.1007/s00213-014-3849-y 5299:Journal of Neurochemistry 5135:10.1007/s00213-013-2986-z 3832:Journal of Neurochemistry 3748:10.1016/j.jad.2015.03.006 3644:10.1007/s11095-017-2323-z 2879:Clinical Pharmacokinetics 2207:and a partial agonist at 2161:are opened downstream of 2010: 1542:Tooltip κ-Opioid receptor 1513:Tooltip δ-Opioid receptor 1486:Tooltip μ-Opioid receptor 831: 806: 786: 764: 751: 724: 719: 700: 668: 640: 612: 584: 556: 528: 500: 480: 447: 419: 391: 386: 373: 360: 344: 334: 324: 316: 229: 224: 199: 187: 172: 146: 116: 102: 84: 64: 51: 46: 37: 28: 19513:Dexecadotril (retorphan) 19485:Enkephalinase inhibitors 19414:BTRX-246040 (LY-2940094) 19396:(Nphe)Nociceptin(1-13)NH 19312:Nociceptin (orphanin FQ) 15700:Atomoxetine (tomoxetine) 14976:Atomoxetine (tomoxetine) 10382:JNJ-40411813 (ADX-71149) 8887:Competitive antagonists: 8795:Polyamine site agonists: 8781:Neboglamine (nebostinel) 8350:Tooltip Kainate receptor 7804:Rubidium chloride (RbCl) 6264:Pediatrics International 5608:Translational Psychiatry 4891:Case Reports in Medicine 4273:10.1177/1087054720902846 4046:10.1177/0269881115602489 3923:10.1177/0269881113478475 3526:10.1177/0269881116636105 3464:10.1177/1087054710379737 3367:10.1186/1471-244X-11-176 3312:Psychological Assessment 2225:absolute bioavailability 2097:NMDA receptor antagonist 1113:Ventricular fibrillation 80:-tolyloxy)propan-1-amine 19211:(Arg14,Lys15)Nociceptin 18482:Dynorphin B (rimorphin) 17524:Nalorphine dinicotinate 16078:mepyramine (pyrilamine) 13151:Eslicarbazepine acetate 9869:Pentamidine isethionate 9613:Traxoprodil (CP-101606) 8852:Epipregnanolone sulfate 7667:Atypical antipsychotics 6439:Mixed amphetamine salts 5697:Neuropsychopharmacology 5220:Neuropsychopharmacology 3632:Pharmaceutical Research 2571:Diário Oficial da União 1108:Ventricular tachycardia 1070:subarachnoid hemorrhage 920:million prescriptions. 18827:Spiradoline (U-62,066) 18772:Pethidine (meperidine) 17965:Pethidine (meperidine) 17655:ADL-5747 (PF-04856881) 17301:4-Caffeoyl-1,5-quinide 17200:Tetrahydropapaveroline 17115:Pethidine (meperidine) 16352:Vanoxerine (GBR-12909) 16199:pethidine (meperidine) 15454:pethidine (meperidine) 14242:Pethidine (meperidine) 12895:Rottlerin (mallotoxin) 11026:Ion channel modulators 9899:Allosteric modulators: 9834:Ipenoxazone (MLV-6976) 9489:Pethidine (meperidine) 9110:Licostinel (ACEA-1021) 9032:Apimostinel (NRX-1074) 8696:Apimostinel (NRX-1074) 8664:Glycine site agonists: 8496:Licostinel (ACEA-1021) 8207:Licostinel (ACEA-1021) 8092:Mibampator (LY-451395) 5975:Electronic Orange Book 2772:TGA eBusiness Services 2397: 2328: 2244:volume of distribution 2131:, atomoxetine reduces 1038:traumatic brain injury 1024:Traumatic brain injury 382:(80%) and faecal (17%) 19518:Ecadotril (sinorphan) 19005:CERC-501 (LY-2456302) 18905:4',7-Dihydroxyflavone 18467:Dinalbuphine sebacate 18342:Alazocine (SKF-10047) 18066:4',7-Dihydroxyflavone 18025:Thiobromadol (C-8813) 17665:Alazocine (SKF-10047) 17311:4',7-Dihydroxyflavone 17291:2-(S)-N,N-(R)-Viminol 16763:Dinalbuphine sebacate 16436:Monoamine neurotoxins 16002:Dosulepin (dothiepin) 15549:Didesmethylcitalopram 15278:Dosulepin (dothiepin) 14955:Serdexmethylphenidate 14257:Serdexmethylphenidate 11252:Ryodipine (riodipine) 9568:CO-101244 (PD-174494) 9284:Delucemine (NPS-1506) 9234:Alazocine (SKF-10047) 6714:Serotonin transporter 6472:Serdexmethylphenidate 6065:on 29 September 2011. 4766:Australian Prescriber 4369:10.1542/peds.87.4.519 4227:10.1089/cap.2013.0054 4188:10.1089/cap.2016.0115 3956:Childress AC (2016). 3674:"The Top 300 of 2021" 3160:10.1089/cap.2012.0093 3108:10.1089/cap.2013.0054 3020:10.1089/cap.2016.0115 2565:(15 September 2023). 2420:Eli Lilly and Company 2395:Eli Lilly and Company 2392: 2326: 2065:serotonin transporter 1330:adrenoceptor agonists 1310:adrenoceptor agonists 1042:sustained attentional 977:adrenoceptor agonists 19375:Sunobinop (S-117957) 19110:N-Fluoropropyl-JDTic 18442:Diamorphine (heroin) 17775:Diamorphine (heroin) 16743:Diamorphine (heroin) 16543:Acetyldihydrocodeine 16523:7-Hydroxymitragynine 16518:7-Acetoxymitragynine 16327:Methoxytetrabenazine 16292:Dihydrotetrabenazine 16106:Arylcyclohexylamines 15401:Arylcyclohexylamines 14552:Dizocilpine (MK-801) 14506:Chaenomeles speciosa 14207:Benocyclidine (BTCP) 13241:Valproate semisodium 11772:Carboxyamidotriazole 11707:Gabapentin enacarbil 11687:Arbaclofen placarbil 9588:Radiprodil (RGH-896) 9563:Buphenine (nylidrin) 9140:Rapastinel (GLYX-13) 8955:Midafotel (d-CPPene) 8862:Pregnenolone sulfate 8786:Rapastinel (GLYX-13) 8577:Pregnenolone sulfate 8318:Pregnenolone sulfate 7788:Hypericum perforatum 7656:Adjunctive therapies 6678:Dopamine transporter 6623:Miscellaneous/others 4320:10.4088/JCP.17m11553 2338:area-under-the-curve 2242:, atomoxetine has a 2240:intravenous delivery 2031:dopamine transporter 1030:cognitive impairment 183:(Swallowed by mouth) 76:-Methyl-3-phenyl-3-( 19578:Ubenimex (bestatin) 19322:Nociceptin (1-13)NH 18930:β-Chlornaltrexamine 18900:4′-Hydroxyflavanone 18322:β-Chlornaltrexamine 18196:N-Benzylnaltrindole 18091:β-Chlornaltrexamine 18010:TAN-67 (SB-205,607) 17675:AR-M100390 (ARM390) 17336:β-Chlornaltrexamine 17306:4′-Hydroxyflavanone 16533:α-Chlornaltrexamine 15951:Threohydrobupropion 15816:Desmethylsertraline 15544:Desmethylcitalopram 15227:Threohydrobupropion 15092:Desmethylsertraline 14747:Threohydrobupropion 14522:Desmethylsertraline 13892:1,10-Phenanthroline 12449:Spooky toxin (SsTx) 11434:Tetrahydropalmatine 8819:-Hydroxycholesterol 8630:Homoquinolinic acid 8603:Main site agonists: 8361:Main site agonists: 7955:5-Fluorowillardiine 7952:Main site agonists: 6804:receptor modulators 6800:reuptake inhibitors 6476:+dexmethylphenidate 5794:10.1124/dmd.31.1.98 5709:10.1038/npp.2010.27 5570:10.2147/DDDT.S50448 4904:10.1155/2011/952584 4728:10.3310/alert_40795 4410:Barkley RA (2015). 3975:10.2147/TCRM.S59270 2603:. 8 February 2021. 2438:Society and culture 2129:Sprague Dawley rats 1377: 1198:(FDA) has issued a 1179:, weight loss, and 1118:Ventricular flutter 1098:Atrial fibrillation 1091:Moderate to severe 1008:(CDS), as multiple 879:executive functions 285:(Prescription only) 248:(Prescription only) 25: 19140:Norbinaltorphimine 18447:Diacetylnalorphine 18136:Diacetylnalorphine 17760:Desmethylclozapine 17414:Diacetylnalorphine 17094:Papaver somniferum 16678:Chloroxymorphamine 16191:dextropropoxyphene 14217:Dexmethylphenidate 13902:7,8-Benzoquinoline 13897:4,7-Phenanthroline 13887:1,7-Phenanthroline 13263:Local anesthetics: 12795:ML-297 (VU0456810) 12302:Diallyl trisulfide 12297:Dextropropoxyphene 12200:Tetraethylammonium 11907:Pinaverium bromide 11677:4-Methylpregabalin 9167:Diethylenetriamine 8846:prasterone sulfate 8621:Homocysteic acid ( 8364:5-Bromowillardiine 7882:Glutamate receptor 7848:Never to phase III 6467:Dexmethylphenidate 5937:Baselt RC (2008). 5620:10.1038/tp.2014.11 5510:Psychopharmacology 5123:Psychopharmacology 3324:10.1037/pas0000006 2719:Medscape Reference 2510:. 22 August 2019. 2398: 2329: 2209:κ-opioid receptors 2205:μ-opioid receptors 1375: 1171:, heart problems, 1163:, liver problems, 950:systematic reviews 901:, heart problems, 893:, liver problems, 877:. It enhances the 21: 19668:2-Tolyl compounds 19633: 19632: 19627: 19626: 19472: 19471: 19317:Nociceptin (1-11) 19188: 19187: 18317:14-Methoxymetopon 18274: 18273: 18191:Methylnaltrindole 17617: 17616: 17286:(3S,4S)-Picenadol 16898:Levacetylmethadol 16444: 16443: 16439: 16225: 16224: 15500: 15475: 15474: 14920:Levophacetoperane 14790: 14765: 14764: 14627:Levophacetoperane 14202:4-Fluoropethidine 14137: 14076: 14075: 14054: 14053: 13993: 13992: 13989: 13988: 13951:Meclofenamic acid 13920: 13919: 13831: 13830: 13723: 13722: 13719: 13718: 13663: 13662: 13599: 13598: 13473:RG7893 (GDC-0287) 13236:Valproate pivoxil 13126:Acetylpheneturide 12981: 12980: 12977: 12976: 12908: 12907: 12880:Meclofenamic acid 12843:Ethanol (alcohol) 12803: 12802: 12752:Minoxidil sulfate 12490: 12489: 11993: 11992: 11989: 11988: 11892:Otilonium bromide 11817:Ethanol (alcohol) 11581:ω-Conotoxin MVIIC 11317:Phenylalkylamines 10992: 10991: 10986: 10985: 10960: 10959: 10909: 10810: 10733: 10629: 10588: 10587: 10281: 10280: 9942: 9941: 9793: 9749:Trichloroethylene 9694:Ethanol (alcohol) 9059: 9002:4-Cl-KYN (AV-101) 8770: 8762: 8729: 8721: 8713: 8670: 8655:Tetrazolylglycine 8624: 8562:Ethanol (alcohol) 8551:sodium thiopental 8369:5-Iodowillardiine 8278:Ethanol (alcohol) 8262:sodium thiopental 7858: 7857: 7817: 7816: 7790:(St. John's Wort) 7741: 7740: 7706:lithium carbonate 7645: 7644: 7641: 7640: 7416: 7415: 7412: 7411: 7225:Amitriptylinoxide 7175: 7174: 7171: 7170: 6747: 6746: 6447:Dextroamphetamine 6411:pharmacotherapies 6276:10.1111/ped.12847 6197:(14): 2193–2204. 5956:978-0-931890-08-6 5885:978-3-540-68706-1 5659:(32): 5180–5185. 5516:(12): 2191–2205. 5182:(15): 4083–4085. 4948:(11): 1219–1227. 4684:10.1002/wps.20765 4674:(Meta-analysis). 4040:(12): 1221–1230. 4018:978-0-470-97948-8 2939:10.2217/PGS.15.93 2933:(13): 1513–1520. 2444:medication errors 2050:nucleus accumbens 2035:prefrontal cortex 2023: 2022: 1553:(partial agonist) 1219:Atomoxetine is a 1200:black box warning 1080:Contraindications 962:drug use disorder 849: 848: 777:Interactive image 670:CompTox Dashboard 308: 293: 280: 268: 256: 243: 162: 129: 19730: 19713:Secondary amines 19650: 19649: 19648: 19641: 19507: 19434:Nociceptin (1-7) 19330:Norbuprenorphine 19267:Dihydroetorphine 19201: 19200: 19090:Methylnaltrexone 19000:Catechin gallate 18732:Norbuprenorphine 18457:Dihydroetorphine 18327:β-Funaltrexamine 18287: 18286: 18186:Methylnaltrexone 18126:Catechin gallate 17940:Norbuprenorphine 17780:Dihydroetorphine 17630: 17629: 17494:Methylnaltrexone 17386:Catechin gallate 17341:β-Funaltrexamine 16753:Dihydroetorphine 16496: 16495: 16471: 16464: 16457: 16448: 16447: 16406: 16393:Antagonist-like: 16287:Deutetrabenazine 16237: 16233: 16177:MIN-117 (WF-516) 16142:Dextromethorphan 15514:6-Nitroquipazine 15504: 15503: 15498: 15494: 15489: 15487: 15483: 14910:Hydroxybupropion 14794: 14793: 14788: 14784: 14779: 14777: 14773: 14667:MIN-117 (WF-516) 14607:Hydroxybupropion 14547:Diphenylpyraline 14278:Diphenylprolinol 14141: 14140: 14135: 14131: 14126: 14124: 14120: 14103: 14096: 14089: 14080: 14079: 14037: 14033: 14012: 14008: 14002: 14001: 13929: 13928: 13847: 13846: 13843: 13839: 13748: 13747: 13744: 13740: 13734: 13733: 13679: 13678: 13675: 13671: 13615: 13614: 13611: 13607: 13226:Sodium valproate 13141:Chlorphenacemide 13123:Anticonvulsants: 13006: 13005: 13002: 12998: 12992: 12991: 12941:Arachidonic acid 12924: 12923: 12920: 12916: 12822: 12821: 12818: 12814: 12791: 12787: 12708: 12704: 12660:Dextromethorphan 12636: 12632: 12528: 12524: 12506: 12505: 12502: 12498: 12018: 12017: 12014: 12010: 12004: 12003: 11976:L-type-selective 11787:Dimeditiapramine 11749:Others/unsorted: 11531:T-type-selective 11518:R-type-selective 11500:P-type-selective 11452:ω-Conotoxin GVIA 11442:N-type-selective 11072:Dihydropyridines 11066:L-type-selective 11053: 11052: 11049: 11045: 11039: 11038: 11019: 11012: 11005: 10996: 10995: 10907: 10887: 10883: 10808: 10788: 10784: 10731: 10716: 10712: 10627: 10612: 10608: 10599: 10598: 10463: 10459: 10305: 10301: 10292: 10291: 10119: 10115: 10005: 10001: 9992: 9991: 9969: 9962: 9955: 9946: 9945: 9791: 9744:Trichloroethanol 9304:Dextromethorphan 9057: 8841: 8830: 8826: 8768: 8760: 8727: 8719: 8711: 8668: 8622: 8593: 8589: 8351: 8347: 8182:Fanapanel (MPQX) 7942: 7938: 7918: 7911: 7904: 7895: 7894: 7877: 7876: 7867:Pharmacodynamics 7862: 7861: 7798: 7764: 7747: 7746: 7720:triiodothyronine 7716:Thyroid hormones 7651: 7650: 7622: 7618: 7562: 7558: 7503:Phenoxypropazine 7435: 7434: 7422: 7421: 7366: 7362: 7208: 7204: 7198: 7197: 7181: 7180: 7060: 7056: 7027: 7023: 6994: 6990: 6961: 6957: 6928: 6924: 6880: 6876: 6822: 6818: 6812: 6811: 6794: 6793: 6774: 6767: 6760: 6751: 6750: 6644:Related articles 6490: 6451:Lisdexamfetamine 6425: 6421: 6410: 6401: 6394: 6387: 6378: 6377: 6372: 6370: 6368: 6323: 6322: 6302: 6296: 6295: 6259: 6253: 6252: 6247: 6240: 6229: 6223: 6222: 6186: 6180: 6179: 6161: 6155: 6154: 6144: 6134: 6110: 6104: 6103: 6101: 6099: 6076: 6067: 6066: 6064: 6058:. Archived from 6057: 6049: 6043: 6042: 6041:on 7 April 2011. 6037:. Archived from 6027: 6021: 6020: 6018: 6016: 6011:. 12 August 2010 6001: 5995: 5994: 5992: 5990: 5967: 5961: 5960: 5944: 5934: 5928: 5927: 5926: 5922: 5915: 5909: 5908: 5907: 5903: 5896: 5890: 5889: 5863: 5857: 5856: 5820: 5814: 5813: 5776: 5767: 5766: 5764: 5762: 5756: 5745: 5741:"atomoxetine HC" 5737: 5731: 5730: 5720: 5703:(7): 1560–1569. 5688: 5677: 5676: 5648: 5642: 5641: 5631: 5599: 5593: 5592: 5582: 5572: 5548: 5542: 5541: 5504: 5498: 5497: 5461: 5452: 5451: 5441: 5409: 5400: 5399: 5379: 5373: 5372: 5331: 5325: 5324: 5314: 5290: 5281: 5280: 5252: 5246: 5245: 5235: 5211: 5200: 5199: 5170: 5157: 5156: 5146: 5114: 5108: 5107: 5105: 5103: 5076: 5070: 5069: 5067: 5065: 5059: 5044: 5036: 5025: 5024: 5014: 4982: 4976: 4975: 4957: 4933: 4927: 4926: 4916: 4906: 4882: 4871: 4870: 4860: 4836: 4830: 4829: 4792: 4786: 4785: 4783: 4781: 4776:on 30 March 2015 4758: 4752: 4751: 4749: 4747: 4712: 4706: 4705: 4695: 4672:World Psychiatry 4663: 4657: 4656: 4627: 4621: 4620: 4610: 4593:(12): CD009221. 4582: 4576: 4575: 4544: 4538: 4537: 4519: 4509: 4485: 4476: 4475: 4447: 4438: 4437: 4435: 4433: 4427: 4416: 4407: 4401: 4400: 4398: 4396: 4348: 4342: 4341: 4331: 4299: 4293: 4292: 4267:(9): 1321–1330. 4255: 4249: 4248: 4238: 4206: 4200: 4199: 4170: 4164: 4163: 4153: 4121: 4115: 4114: 4104: 4072: 4066: 4065: 4029: 4023: 4022: 4004: 3998: 3997: 3987: 3977: 3953: 3944: 3943: 3925: 3901: 3892: 3891: 3862: 3856: 3855: 3826: 3820: 3819: 3817: 3815: 3796: 3790: 3789: 3787: 3785: 3766: 3760: 3759: 3730: 3724: 3723: 3721: 3719: 3700: 3694: 3693: 3691: 3689: 3670: 3664: 3663: 3627: 3618: 3617: 3615: 3613: 3594: 3585: 3584: 3567: 3558: 3557: 3555: 3553: 3505: 3496: 3495: 3493: 3491: 3443: 3434: 3433: 3423: 3399: 3390: 3389: 3379: 3369: 3345: 3336: 3335: 3318:(4): 1095–1105. 3306: 3300: 3299: 3289: 3257: 3251: 3250: 3221: 3215: 3214: 3209: 3207: 3188: 3182: 3181: 3171: 3139: 3130: 3129: 3119: 3087: 3081: 3080: 3070: 3038: 3032: 3031: 3002: 2996: 2995: 2993: 2991: 2972: 2951: 2950: 2927:Pharmacogenomics 2922: 2911: 2910: 2874: 2829: 2828: 2826: 2824: 2805: 2788: 2787: 2785: 2783: 2764: 2735: 2734: 2732: 2730: 2711: 2694: 2693: 2691: 2689: 2683: 2672: 2664: 2658: 2657: 2655: 2653: 2634: 2617: 2616: 2614: 2612: 2593: 2587: 2586: 2584: 2582: 2559: 2553: 2552: 2550: 2548: 2538:nctr-crs.fda.gov 2530: 2524: 2523: 2521: 2519: 2500: 2480:bipolar disorder 2473:major depression 2376: 2364: 2332:Pharmacogenomics 2215:Pharmacokinetics 2201:opioid receptors 1990: 1985: 1966: 1961: 1942: 1937: 1766: 1761: 1743: 1738: 1701: 1696: 1678: 1673: 1655: 1650: 1628: 1623: 1581: 1576: 1558: 1543: 1539: 1530: 1519: 1514: 1510: 1502: 1487: 1483: 1474: 1469: 1438: 1434: 1425: 1409: 1405: 1396: 1391: 1386: 1378: 1374: 1371:Pharmacodynamics 1284:sympathomimetics 1282:Indirect-acting 1277:Antihypertensive 1137:Pheochromocytoma 1124:arteriosclerosis 919: 913:is not certain. 875:psychostimulants 845: 844: 837: 779: 759: 747: 744: 738: 732: 715: 704: 693: 692: 678: 676: 661: 653: 633: 625: 605: 597: 577: 569: 549: 541: 521: 513: 493: 473: 465: 455: 454: 440: 432: 365: 306: 303: 298: 291: 288: 278: 275: 267: 264: 254: 251: 241: 238: 216: 160: 157: 139: 128: 125: 112: 98: 42: 33: 26: 24: 20: 19738: 19737: 19733: 19732: 19731: 19729: 19728: 19727: 19658: 19657: 19656: 19646: 19644: 19636: 19634: 19629: 19628: 19623: 19505: 19468: 19399: 19384: 19325: 19247: 19239: 19231: 19227: 19219: 19196: 19184: 18980:Binaltorphimine 18925:6β-Naltrexol-d4 18888: 18507:Ethylketazocine 18462:Dihydromorphine 18282: 18270: 18081:6β-Naltrexol-d4 18054: 17810:Ethylketazocine 17785:Dihydromorphine 17625: 17613: 17321:6β-Naltrexol-d4 17274: 17073:Oxymorphonazine 16828:Furanylfentanyl 16758:Dihydromorphine 16613:Benzhydrocodone 16502: 16500: 16491: 16483: 16478:Opioid receptor 16475: 16445: 16440: 16400: 16378:DAT modulators: 16356: 16257:methamphetamine 16235: 16221: 16132:Cyclobenzaprine 16074:diphenhydramine 16062:brompheniramine 16036: 15965: 15764: 15730:Levomilnacipran 15688: 15496: 15488: 15485: 15471: 15369:brompheniramine 15353: 15317: 15241: 15040: 15001:Levomilnacipran 14964: 14935:Methylphenidate 14878: 14786: 14778: 14775: 14761: 14448: 14302: 14266: 14237:Methylphenidate 14212:Desoxypipradrol 14190: 14133: 14125: 14122: 14112: 14107: 14077: 14072: 14050: 14035: 14025: 14010: 13985: 13981:Trifluoperazine 13976:Tolfenamic acid 13946:Flufenamic acid 13916: 13873: 13841: 13827: 13809: 13775:Flufenamic acid 13770:Ethacrynic acid 13742: 13715: 13673: 13659: 13641: 13609: 13595: 13542: 13373:Metabutoxycaine 13338:Diphenhydramine 13328:Cyclomethycaine 13293:Levobupivacaine 13000: 12973: 12955: 12918: 12904: 12900:Tolfenamic acid 12875:Flufenamic acid 12870: 12852: 12838: 12816: 12813: 12799: 12789: 12706: 12703: 12684: 12634: 12526: 12523: 12500: 12486: 12471: 12453: 12433: 12342:Norpropoxyphene 12219:11.1)-specific: 12218: 12012: 11985: 11961: 11917:Rhynchophylline 11667: 11047: 11028: 11023: 10993: 10988: 10987: 10982: 10956: 10885: 10882: 10872: 10786: 10783: 10773: 10714: 10711: 10701: 10610: 10607: 10584: 10461: 10458: 10448: 10303: 10300: 10277: 10169:Quisqualic acid 10117: 10114: 10104: 10035:Quisqualic acid 10003: 10000: 9981: 9973: 9943: 9938: 9906: 9804:Flufenamic acid 9739:Trichloroethane 9514:Rhynchophylline 9434:Methoxphenidine 9399:Levomilnacipran 9299:Dextromethadone 9224:α-Endopsychosin 8828: 8740:Dimethylglycine 8650:Quinolinic acid 8591: 8581: 8419:Quisqualic acid 8349: 8339: 7995:Quisqualic acid 7940: 7930: 7922: 7887: 7869: 7859: 7854: 7853: 7838:Clinical trials 7813: 7752: 7737: 7733: 7725: 7710:lithium citrate 7658: 7637: 7620: 7617: 7607: 7560: 7557: 7547: 7523:Tranylcypromine 7429: 7408: 7392: 7364: 7354: 7206: 7192: 7167: 7076: 7058: 7048: 7025: 7015: 6992: 6982: 6959: 6949: 6926: 6916: 6897:Levomilnacipran 6878: 6868: 6820: 6806: 6788: 6781:Antidepressants 6778: 6748: 6743: 6639: 6618: 6556:Antidepressants 6550: 6531: 6528: 6519: 6487: 6481: 6462:Methylphenidate 6457:Methamphetamine 6443:Levoamphetamine 6423: 6413: 6405: 6375: 6366: 6364: 6337:Dean L (2015). 6332: 6330:Further reading 6327: 6326: 6313:(12): 692–698. 6303: 6299: 6260: 6256: 6245: 6238: 6230: 6226: 6187: 6183: 6176: 6162: 6158: 6111: 6107: 6097: 6095: 6078: 6077: 6070: 6062: 6055: 6051: 6050: 6046: 6029: 6028: 6024: 6014: 6012: 6003: 6002: 5998: 5988: 5986: 5969: 5968: 5964: 5957: 5935: 5931: 5924: 5916: 5912: 5905: 5897: 5893: 5886: 5864: 5860: 5821: 5817: 5777: 5770: 5760: 5758: 5754: 5743: 5739: 5738: 5734: 5689: 5680: 5649: 5645: 5600: 5596: 5549: 5545: 5505: 5501: 5462: 5455: 5410: 5403: 5380: 5376: 5332: 5328: 5291: 5284: 5253: 5249: 5212: 5203: 5171: 5160: 5115: 5111: 5101: 5099: 5087: 5077: 5073: 5063: 5061: 5057: 5042: 5038: 5037: 5028: 4983: 4979: 4934: 4930: 4883: 4874: 4858:10.18433/j3h03r 4837: 4833: 4793: 4789: 4779: 4777: 4760: 4759: 4755: 4745: 4743: 4714: 4713: 4709: 4664: 4660: 4628: 4624: 4583: 4579: 4545: 4541: 4486: 4479: 4448: 4441: 4431: 4429: 4425: 4414: 4408: 4404: 4394: 4392: 4349: 4345: 4314:(2): 17m11553. 4300: 4296: 4256: 4252: 4207: 4203: 4171: 4167: 4122: 4118: 4073: 4069: 4030: 4026: 4019: 4005: 4001: 3954: 3947: 3902: 3895: 3863: 3859: 3827: 3823: 3813: 3811: 3798: 3797: 3793: 3783: 3781: 3768: 3767: 3763: 3731: 3727: 3717: 3715: 3702: 3701: 3697: 3687: 3685: 3672: 3671: 3667: 3628: 3621: 3611: 3609: 3596: 3595: 3588: 3581: 3569: 3568: 3561: 3551: 3549: 3506: 3499: 3489: 3487: 3444: 3437: 3400: 3393: 3346: 3339: 3307: 3303: 3258: 3254: 3222: 3218: 3205: 3203: 3190: 3189: 3185: 3140: 3133: 3088: 3084: 3039: 3035: 3003: 2999: 2989: 2987: 2974: 2973: 2954: 2923: 2914: 2875: 2832: 2822: 2820: 2807: 2806: 2791: 2781: 2779: 2766: 2765: 2738: 2728: 2726: 2713: 2712: 2697: 2687: 2685: 2681: 2670: 2666: 2665: 2661: 2651: 2649: 2636: 2635: 2620: 2610: 2608: 2595: 2594: 2590: 2580: 2578: 2560: 2556: 2546: 2544: 2532: 2531: 2527: 2517: 2515: 2502: 2501: 2497: 2492: 2469: 2456: 2440: 2422:, the original 2412: 2403: 2387: 2380: 2377: 2368: 2365: 2349: 2334: 2284: 2279: 2249: 2233: 2217: 2194: 2187: 2180: 2173: 2166: 2156: 2124: 2112: 2105: 2054:methylphenidate 2052:; in contrast, 2014: 1975: 1951: 1927: 1908: 1889: 1870: 1851: 1832: 1813: 1794: 1775: 1752: 1729: 1710: 1687: 1664: 1641: 1591: 1567: 1541: 1512: 1485: 1436: 1407: 1373: 1368: 1329: 1309: 1288:pseudoephedrine 1263:QT prolongation 1255: 1217: 1209: 1157: 1155:Adverse effects 1082: 1066:akinetic mutism 1062:Cochrane review 1026: 1018:methylphenidate 1002: 997: 976: 954:methylphenidate 938: 928:Atomoxetine is 926: 917: 884:methylphenidate 840: 838: 835:(what is this?) 832: 827: 824: 819: 814: 813: 802: 799: 794: 793: 782: 757: 741: 735: 696: 672: 664: 636: 608: 580: 552: 524: 496: 476: 451: 443: 415: 412: 399: 398: 363: 336:Protein binding 326:Bioavailability 318:Pharmacokinetic 312: 296: 220: 175: 168: 149: 142: 17: 12: 11: 5: 19736: 19726: 19725: 19720: 19715: 19710: 19705: 19700: 19695: 19690: 19685: 19680: 19675: 19670: 19655: 19654: 19631: 19630: 19625: 19624: 19622: 19621: 19611: 19610: 19605: 19600: 19595: 19590: 19581: 19580: 19575: 19570: 19565: 19560: 19555: 19550: 19545: 19540: 19535: 19530: 19525: 19520: 19515: 19510: 19508:-Phenylalanine 19502: 19497: 19492: 19480: 19478: 19474: 19473: 19470: 19469: 19467: 19466: 19461: 19456: 19451: 19446: 19441: 19436: 19431: 19426: 19421: 19416: 19411: 19406: 19401: 19397: 19392: 19390: 19386: 19385: 19383: 19382: 19377: 19372: 19367: 19362: 19357: 19352: 19347: 19342: 19337: 19335:Racemethorphan 19332: 19327: 19323: 19319: 19314: 19309: 19304: 19299: 19294: 19289: 19284: 19282:Levomethorphan 19279: 19274: 19269: 19264: 19259: 19254: 19249: 19245: 19241: 19237: 19233: 19229: 19225: 19221: 19217: 19213: 19207: 19205: 19198: 19190: 19189: 19186: 19185: 19183: 19182: 19177: 19172: 19167: 19162: 19157: 19152: 19147: 19142: 19137: 19132: 19127: 19122: 19117: 19112: 19107: 19102: 19097: 19092: 19087: 19082: 19077: 19072: 19067: 19062: 19057: 19052: 19047: 19042: 19037: 19032: 19027: 19022: 19017: 19012: 19007: 19002: 18997: 18992: 18987: 18982: 18977: 18972: 18967: 18962: 18957: 18952: 18947: 18942: 18937: 18932: 18927: 18922: 18917: 18912: 18907: 18902: 18896: 18894: 18890: 18889: 18887: 18886: 18881: 18876: 18871: 18866: 18844: 18839: 18834: 18829: 18824: 18819: 18814: 18809: 18799: 18794: 18789: 18787:Racemethorphan 18784: 18779: 18774: 18769: 18764: 18759: 18754: 18749: 18744: 18739: 18734: 18729: 18724: 18719: 18714: 18709: 18704: 18699: 18694: 18689: 18684: 18679: 18674: 18669: 18664: 18659: 18654: 18649: 18644: 18639: 18634: 18629: 18624: 18619: 18614: 18609: 18607:Levomethorphan 18604: 18599: 18594: 18589: 18584: 18579: 18574: 18569: 18564: 18559: 18554: 18549: 18544: 18539: 18534: 18529: 18524: 18519: 18514: 18509: 18504: 18499: 18494: 18489: 18484: 18479: 18474: 18469: 18464: 18459: 18454: 18449: 18444: 18439: 18434: 18429: 18424: 18419: 18414: 18409: 18404: 18399: 18394: 18389: 18384: 18379: 18374: 18369: 18364: 18359: 18354: 18349: 18344: 18339: 18334: 18329: 18324: 18319: 18314: 18309: 18304: 18299: 18293: 18291: 18284: 18276: 18275: 18272: 18271: 18269: 18268: 18263: 18258: 18253: 18248: 18243: 18238: 18233: 18228: 18223: 18218: 18213: 18208: 18203: 18198: 18193: 18188: 18183: 18178: 18173: 18168: 18163: 18158: 18153: 18148: 18143: 18138: 18133: 18128: 18123: 18118: 18113: 18108: 18103: 18098: 18093: 18088: 18083: 18078: 18073: 18068: 18062: 18060: 18056: 18055: 18053: 18052: 18047: 18042: 18037: 18032: 18027: 18022: 18017: 18012: 18007: 18002: 17997: 17992: 17987: 17982: 17977: 17975:Racemethorphan 17972: 17967: 17962: 17957: 17952: 17947: 17942: 17937: 17932: 17927: 17922: 17917: 17912: 17907: 17902: 17897: 17892: 17887: 17885:Levomethorphan 17882: 17880:Leu-enkephalin 17877: 17872: 17867: 17862: 17857: 17852: 17847: 17842: 17837: 17832: 17827: 17822: 17817: 17812: 17807: 17802: 17797: 17792: 17787: 17782: 17777: 17772: 17767: 17762: 17757: 17752: 17747: 17742: 17737: 17732: 17727: 17722: 17717: 17712: 17707: 17702: 17697: 17692: 17687: 17682: 17677: 17672: 17667: 17662: 17657: 17652: 17647: 17642: 17636: 17634: 17627: 17619: 17618: 17615: 17614: 17612: 17611: 17606: 17601: 17596: 17591: 17586: 17581: 17576: 17571: 17566: 17561: 17559:Naltrexonazine 17556: 17551: 17546: 17541: 17536: 17531: 17526: 17521: 17516: 17511: 17506: 17501: 17496: 17491: 17486: 17481: 17476: 17471: 17466: 17461: 17456: 17451: 17446: 17441: 17436: 17431: 17426: 17421: 17416: 17411: 17406: 17401: 17396: 17393: 17388: 17383: 17378: 17373: 17368: 17363: 17358: 17353: 17348: 17343: 17338: 17333: 17328: 17323: 17318: 17313: 17308: 17303: 17298: 17293: 17288: 17282: 17280: 17276: 17275: 17273: 17272: 17267: 17262: 17257: 17252: 17247: 17242: 17237: 17232: 17227: 17222: 17217: 17212: 17207: 17202: 17197: 17192: 17187: 17182: 17177: 17172: 17167: 17162: 17160:Racemethorphan 17157: 17152: 17147: 17142: 17137: 17132: 17127: 17122: 17117: 17112: 17107: 17102: 17090: 17085: 17080: 17075: 17070: 17065: 17060: 17055: 17050: 17045: 17040: 17035: 17030: 17025: 17020: 17015: 17010: 17005: 17000: 16995: 16990: 16985: 16980: 16975: 16970: 16965: 16960: 16955: 16950: 16945: 16940: 16935: 16930: 16925: 16920: 16915: 16910: 16905: 16903:Levomethorphan 16900: 16895: 16893:Leu-enkephalin 16890: 16885: 16880: 16875: 16870: 16865: 16860: 16855: 16853:Hydromorphinol 16850: 16845: 16840: 16835: 16830: 16825: 16820: 16815: 16810: 16805: 16800: 16795: 16790: 16785: 16780: 16775: 16770: 16765: 16760: 16755: 16750: 16748:Dihydrocodeine 16745: 16740: 16735: 16730: 16725: 16720: 16715: 16713:Dextromoramide 16710: 16705: 16700: 16695: 16690: 16685: 16680: 16675: 16670: 16665: 16660: 16655: 16650: 16645: 16640: 16635: 16630: 16625: 16620: 16618:Benzylmorphine 16615: 16610: 16605: 16600: 16595: 16590: 16585: 16580: 16575: 16570: 16565: 16560: 16555: 16550: 16548:Acetylfentanyl 16545: 16540: 16535: 16530: 16525: 16520: 16515: 16509: 16507: 16493: 16485: 16484: 16474: 16473: 16466: 16459: 16451: 16442: 16441: 16405: 16402: 16401: 16399: 16398: 16386: 16374: 16373: 16368:DAT enhancers: 16364: 16362: 16358: 16357: 16355: 16354: 16349: 16344: 16339: 16334: 16329: 16324: 16319: 16314: 16309: 16304: 16299: 16294: 16289: 16284: 16279: 16274: 16269: 16264: 16246: 16240: 16238: 16227: 16226: 16223: 16222: 16220: 16219: 16214: 16184: 16179: 16174: 16169: 16164: 16159: 16154: 16149: 16144: 16139: 16134: 16129: 16103: 16092:Antipsychotics 16089: 16086:tripelennamine 16070:dimenhydrinate 16066:chlorphenamine 16058:Antihistamines 16055: 16050: 16041: 16038: 16037: 16035: 16034: 16029: 16024: 16019: 16014: 16009: 16004: 15999: 15994: 15992:Cyanodothiepin 15989: 15984: 15979: 15970: 15967: 15966: 15964: 15963: 15953: 15948: 15943: 15938: 15933: 15928: 15923: 15918: 15913: 15908: 15903: 15898: 15893: 15888: 15883: 15878: 15873: 15868: 15863: 15858: 15853: 15848: 15843: 15838: 15833: 15828: 15823: 15818: 15813: 15808: 15803: 15798: 15793: 15788: 15783: 15778: 15769: 15766: 15765: 15763: 15762: 15757: 15752: 15747: 15742: 15737: 15732: 15727: 15722: 15717: 15715:Desvenlafaxine 15712: 15707: 15702: 15693: 15690: 15689: 15687: 15686: 15681: 15676: 15671: 15666: 15661: 15656: 15651: 15646: 15641: 15632: 15631: 15626: 15621: 15616: 15611: 15606: 15601: 15596: 15591: 15586: 15581: 15576: 15571: 15566: 15561: 15556: 15551: 15546: 15541: 15536: 15531: 15526: 15521: 15516: 15507: 15501: 15477: 15476: 15473: 15472: 15470: 15469: 15439: 15434: 15429: 15422: 15417: 15412: 15398: 15387:Antipsychotics 15384: 15381:tripelennamine 15373:chlorphenamine 15365:Antihistamines 15358: 15355: 15354: 15352: 15351: 15346: 15341: 15336: 15331: 15322: 15319: 15318: 15316: 15315: 15310: 15305: 15300: 15295: 15290: 15285: 15280: 15275: 15270: 15265: 15260: 15255: 15246: 15243: 15242: 15240: 15239: 15229: 15224: 15219: 15214: 15209: 15204: 15199: 15194: 15189: 15184: 15179: 15174: 15169: 15164: 15159: 15154: 15149: 15144: 15139: 15134: 15129: 15124: 15119: 15114: 15109: 15104: 15099: 15094: 15089: 15084: 15079: 15074: 15069: 15064: 15059: 15054: 15045: 15042: 15041: 15039: 15038: 15033: 15028: 15023: 15018: 15013: 15008: 15003: 14998: 14993: 14988: 14986:Desvenlafaxine 14983: 14978: 14969: 14966: 14965: 14963: 14962: 14957: 14952: 14947: 14942: 14937: 14932: 14927: 14922: 14917: 14912: 14907: 14902: 14897: 14892: 14883: 14880: 14879: 14877: 14876: 14871: 14866: 14861: 14856: 14851: 14846: 14841: 14836: 14831: 14826: 14821: 14816: 14811: 14806: 14797: 14791: 14767: 14766: 14763: 14762: 14760: 14759: 14754: 14752:Tripelennamine 14749: 14744: 14739: 14734: 14729: 14724: 14719: 14714: 14709: 14704: 14699: 14694: 14689: 14684: 14679: 14674: 14669: 14664: 14659: 14654: 14649: 14644: 14639: 14634: 14629: 14624: 14619: 14614: 14609: 14604: 14599: 14594: 14589: 14584: 14579: 14574: 14569: 14564: 14559: 14554: 14549: 14544: 14539: 14534: 14529: 14524: 14519: 14514: 14509: 14502: 14497: 14492: 14487: 14482: 14477: 14475:Amfonelic acid 14472: 14467: 14462: 14453: 14450: 14449: 14447: 14446: 14441: 14436: 14431: 14426: 14421: 14416: 14411: 14406: 14401: 14396: 14391: 14386: 14381: 14376: 14371: 14366: 14361: 14356: 14351: 14346: 14341: 14336: 14331: 14326: 14321: 14316: 14307: 14304: 14303: 14301: 14300: 14295: 14290: 14285: 14280: 14271: 14268: 14267: 14265: 14264: 14259: 14254: 14249: 14244: 14239: 14234: 14229: 14227:Ethylphenidate 14224: 14219: 14214: 14209: 14204: 14195: 14192: 14191: 14189: 14188: 14183: 14178: 14173: 14168: 14163: 14158: 14153: 14144: 14138: 14114: 14113: 14106: 14105: 14098: 14091: 14083: 14074: 14073: 14059: 14056: 14055: 14052: 14051: 14049: 14048: 14040: 14038: 14027: 14026: 14024: 14023: 14015: 14013: 13999: 13995: 13994: 13991: 13990: 13987: 13986: 13984: 13983: 13978: 13973: 13968: 13963: 13958: 13956:Mefenamic acid 13953: 13948: 13943: 13937: 13935: 13926: 13922: 13921: 13918: 13917: 13915: 13914: 13912:Phenanthridine 13909: 13904: 13899: 13894: 13889: 13883: 13881: 13875: 13874: 13872: 13871: 13866: 13861: 13855: 13853: 13844: 13833: 13832: 13829: 13828: 13826: 13825: 13819: 13817: 13811: 13810: 13808: 13807: 13802: 13797: 13792: 13787: 13782: 13777: 13772: 13767: 13762: 13756: 13754: 13745: 13731: 13725: 13724: 13721: 13720: 13717: 13716: 13714: 13713: 13708: 13703: 13698: 13693: 13687: 13685: 13676: 13665: 13664: 13661: 13660: 13658: 13657: 13651: 13649: 13643: 13642: 13640: 13639: 13634: 13629: 13623: 13621: 13612: 13601: 13600: 13597: 13596: 13594: 13593: 13588: 13583: 13578: 13573: 13560:Atracotoxins ( 13558: 13552: 13550: 13544: 13543: 13541: 13540: 13535: 13530: 13520: 13515: 13506: 13505: 13503:Zetekitoxin AB 13500: 13495: 13490: 13485: 13476: 13475: 13470: 13465: 13460: 13455: 13450: 13445: 13440: 13435: 13430: 13421: 13420: 13415: 13410: 13405: 13403:Proxymetacaine 13400: 13395: 13390: 13385: 13380: 13375: 13370: 13365: 13360: 13355: 13350: 13345: 13340: 13335: 13330: 13325: 13320: 13315: 13313:Chloroprocaine 13310: 13305: 13300: 13286: 13281: 13276: 13271: 13259: 13258: 13253: 13248: 13243: 13238: 13233: 13228: 13223: 13218: 13213: 13208: 13203: 13198: 13193: 13188: 13183: 13178: 13173: 13168: 13163: 13158: 13153: 13148: 13143: 13138: 13133: 13128: 13119: 13118: 13113: 13108: 13103: 13098: 13093: 13088: 13083: 13078: 13073: 13068: 13063: 13058: 13053: 13048: 13043: 13038: 13033: 13024: 13023: 13014: 13012: 13003: 12989: 12983: 12982: 12979: 12978: 12975: 12974: 12972: 12971: 12965: 12963: 12957: 12956: 12954: 12953: 12948: 12943: 12938: 12932: 12930: 12921: 12910: 12909: 12906: 12905: 12903: 12902: 12897: 12892: 12887: 12882: 12877: 12868: 12862: 12860: 12854: 12853: 12851: 12850: 12845: 12836: 12830: 12828: 12819: 12811: 12805: 12804: 12801: 12800: 12798: 12797: 12780: 12779: 12774: 12769: 12764: 12759: 12754: 12749: 12744: 12739: 12734: 12729: 12724: 12719: 12714: 12701: 12694: 12692: 12686: 12685: 12683: 12682: 12677: 12672: 12667: 12662: 12657: 12652: 12647: 12642: 12625: 12624: 12619: 12614: 12609: 12604: 12599: 12594: 12589: 12587:Glyclopyramide 12584: 12579: 12574: 12569: 12564: 12559: 12554: 12549: 12544: 12542:Chlorpropamide 12539: 12534: 12521: 12514: 12512: 12503: 12492: 12491: 12488: 12487: 12485: 12484: 12479: 12469: 12463: 12461: 12455: 12454: 12452: 12451: 12446: 12441: 12431: 12425: 12424: 12419: 12414: 12409: 12404: 12399: 12394: 12389: 12384: 12379: 12374: 12369: 12364: 12359: 12354: 12349: 12344: 12339: 12334: 12329: 12324: 12319: 12314: 12309: 12304: 12299: 12294: 12289: 12287:Clarithromycin 12284: 12279: 12277:Chlorpromazine 12274: 12269: 12264: 12259: 12254: 12249: 12244: 12239: 12234: 12229: 12224: 12216: 12208: 12207: 12202: 12197: 12192: 12187: 12182: 12177: 12172: 12167: 12162: 12157: 12152: 12147: 12142: 12137: 12132: 12127: 12122: 12117: 12112: 12107: 12102: 12097: 12092: 12087: 12082: 12077: 12072: 12067: 12062: 12057: 12052: 12047: 12042: 12037: 12032: 12026: 12024: 12015: 12001: 11995: 11994: 11991: 11990: 11987: 11986: 11984: 11983: 11971: 11969: 11963: 11962: 11960: 11959: 11954: 11949: 11944: 11939: 11934: 11929: 11924: 11919: 11914: 11909: 11904: 11899: 11897:Paramethadione 11894: 11889: 11884: 11879: 11874: 11869: 11864: 11859: 11854: 11849: 11844: 11839: 11834: 11829: 11824: 11819: 11814: 11809: 11804: 11799: 11794: 11789: 11784: 11779: 11774: 11769: 11764: 11759: 11754: 11745: 11744: 11739: 11734: 11729: 11724: 11719: 11714: 11709: 11704: 11699: 11694: 11689: 11684: 11679: 11672:gabapentinoids 11665: 11659: 11658: 11653: 11648: 11643: 11638: 11633: 11628: 11623: 11618: 11613: 11608: 11603: 11598: 11593: 11588: 11583: 11578: 11573:Non-selective: 11569: 11568: 11563: 11558: 11553: 11548: 11543: 11538: 11526: 11525: 11513: 11512: 11510:ω-Agatoxin IVB 11507: 11505:ω-Agatoxin IVA 11495: 11494: 11489: 11484: 11479: 11474: 11469: 11464: 11462:Huwentoxin XVI 11459: 11454: 11449: 11437: 11436: 11431: 11426: 11421: 11416: 11414:Cyproheptadine 11411: 11406: 11401: 11396: 11384: 11379: 11374: 11369: 11364: 11359: 11354: 11349: 11344: 11339: 11334: 11329: 11324: 11309: 11304: 11299: 11294: 11279: 11274: 11269: 11264: 11259: 11254: 11249: 11244: 11239: 11234: 11229: 11224: 11219: 11214: 11209: 11204: 11199: 11194: 11189: 11184: 11179: 11174: 11172:Levniguldipine 11169: 11164: 11159: 11154: 11149: 11144: 11139: 11134: 11129: 11124: 11119: 11114: 11112:Dexniguldipine 11109: 11104: 11099: 11094: 11089: 11084: 11079: 11061: 11059: 11050: 11036: 11030: 11029: 11022: 11021: 11014: 11007: 10999: 10990: 10989: 10984: 10983: 10965: 10962: 10961: 10958: 10957: 10955: 10954: 10949: 10944: 10939: 10934: 10929: 10920: 10919: 10904: 10899: 10890: 10888: 10880: 10874: 10873: 10871: 10870: 10858: 10853: 10848: 10843: 10838: 10833: 10828: 10819: 10818: 10813: 10805: 10800: 10791: 10789: 10781: 10775: 10774: 10772: 10771: 10766: 10761: 10756: 10751: 10746: 10737: 10736: 10728: 10719: 10717: 10709: 10703: 10702: 10700: 10699: 10694: 10689: 10684: 10679: 10674: 10665: 10664: 10659: 10647: 10642: 10637: 10632: 10624: 10615: 10613: 10605: 10596: 10590: 10589: 10586: 10585: 10583: 10582: 10577: 10565: 10560: 10555: 10550: 10545: 10540: 10535: 10526: 10525: 10520: 10515: 10510: 10505: 10500: 10495: 10490: 10485: 10480: 10475: 10466: 10464: 10456: 10450: 10449: 10447: 10446: 10441: 10429: 10424: 10419: 10414: 10409: 10404: 10399: 10394: 10385: 10384: 10372: 10367: 10362: 10357: 10352: 10347: 10342: 10337: 10332: 10327: 10322: 10317: 10308: 10306: 10298: 10289: 10283: 10282: 10279: 10278: 10276: 10275: 10270: 10265: 10260: 10255: 10250: 10245: 10240: 10228: 10223: 10218: 10213: 10208: 10203: 10198: 10193: 10184: 10183: 10171: 10166: 10161: 10156: 10151: 10146: 10141: 10136: 10131: 10122: 10120: 10112: 10106: 10105: 10103: 10102: 10097: 10092: 10087: 10082: 10077: 10072: 10063: 10062: 10057: 10052: 10047: 10042: 10037: 10032: 10027: 10022: 10017: 10008: 10006: 9998: 9989: 9983: 9982: 9972: 9971: 9964: 9957: 9949: 9940: 9939: 9937: 9936: 9929: 9922: 9911: 9908: 9907: 9905: 9904: 9892: 9891: 9881: 9876: 9871: 9866: 9861: 9856: 9851: 9846: 9841: 9836: 9831: 9826: 9821: 9816: 9811: 9806: 9801: 9796: 9788: 9783: 9778: 9773: 9761: 9756: 9751: 9746: 9741: 9736: 9731: 9726: 9721: 9716: 9714:Methoxyflurane 9711: 9706: 9701: 9696: 9691: 9686: 9681: 9676: 9671: 9666: 9661: 9649: 9644: 9632: 9627: 9622: 9610: 9605: 9600: 9595: 9590: 9585: 9580: 9575: 9570: 9565: 9560: 9555: 9546: 9541: 9536: 9531: 9526: 9521: 9516: 9511: 9506: 9501: 9496: 9491: 9486: 9481: 9476: 9471: 9466: 9461: 9459:Nitromemantine 9456: 9451: 9446: 9441: 9436: 9431: 9426: 9421: 9416: 9411: 9406: 9401: 9396: 9394:Levomethorphan 9391: 9386: 9381: 9376: 9371: 9366: 9361: 9356: 9351: 9346: 9341: 9336: 9331: 9326: 9321: 9316: 9314:Dieticyclidine 9311: 9306: 9301: 9296: 9294:Dextrallorphan 9291: 9286: 9281: 9276: 9271: 9266: 9261: 9256: 9251: 9249:Argiotoxin-636 9246: 9241: 9236: 9231: 9226: 9221: 9216: 9211: 9206: 9201: 9196: 9191: 9186: 9174: 9169: 9164: 9162:Diaminopropane 9159: 9154: 9142: 9137: 9132: 9127: 9122: 9117: 9112: 9107: 9102: 9097: 9092: 9090:Kynurenic acid 9087: 9082: 9077: 9072: 9067: 9062: 9054: 9049: 9044: 9039: 9034: 9029: 9024: 9019: 9014: 9009: 9004: 8992: 8987: 8982: 8977: 8972: 8967: 8962: 8957: 8952: 8947: 8942: 8937: 8932: 8927: 8922: 8917: 8912: 8907: 8902: 8897: 8892: 8880: 8879: 8874: 8869: 8864: 8859: 8854: 8849: 8836: 8821: 8805: 8800: 8788: 8783: 8778: 8773: 8765: 8757: 8752: 8747: 8742: 8737: 8732: 8724: 8716: 8708: 8703: 8698: 8693: 8688: 8683: 8678: 8673: 8657: 8652: 8647: 8642: 8637: 8632: 8627: 8618: 8613: 8608: 8596: 8594: 8583: 8582: 8580: 8579: 8574: 8569: 8564: 8559: 8554: 8533: 8528: 8523: 8518: 8513: 8508: 8503: 8498: 8493: 8491:Kynurenic acid 8488: 8483: 8478: 8473: 8468: 8463: 8454: 8453: 8448: 8443: 8438: 8433: 8421: 8416: 8411: 8406: 8401: 8396: 8391: 8386: 8381: 8376: 8371: 8366: 8354: 8352: 8341: 8340: 8338: 8337: 8325: 8320: 8315: 8310: 8305: 8300: 8295: 8290: 8285: 8280: 8275: 8270: 8265: 8244: 8239: 8234: 8229: 8224: 8219: 8214: 8209: 8204: 8199: 8197:Kynurenic acid 8194: 8189: 8184: 8179: 8174: 8169: 8164: 8159: 8154: 8149: 8140: 8139: 8134: 8129: 8124: 8119: 8114: 8109: 8104: 8099: 8094: 8089: 8084: 8079: 8074: 8069: 8064: 8059: 8054: 8049: 8044: 8039: 8034: 8029: 8024: 8019: 8014: 8009: 7997: 7992: 7987: 7982: 7977: 7972: 7967: 7962: 7957: 7945: 7943: 7932: 7931: 7921: 7920: 7913: 7906: 7898: 7892: 7889: 7888: 7874: 7871: 7870: 7856: 7855: 7852: 7851: 7850: 7849: 7846: 7835: 7829: 7823: 7822: 7819: 7818: 7815: 7814: 7812: 7811: 7806: 7801: 7792: 7784: 7767: 7761:Ademetionine ( 7757: 7754: 7753: 7743: 7742: 7739: 7738: 7736: 7735: 7731: 7723: 7713: 7699: 7694: 7663: 7660: 7659: 7647: 7646: 7643: 7642: 7639: 7638: 7636: 7635: 7626: 7624: 7615: 7609: 7608: 7606: 7605: 7600: 7595: 7590: 7585: 7580: 7575: 7566: 7564: 7555: 7549: 7548: 7546: 7545: 7536: 7535: 7526: 7525: 7520: 7515: 7510: 7505: 7500: 7495: 7490: 7485: 7480: 7475: 7470: 7465: 7460: 7455: 7450: 7441: 7439: 7431: 7430: 7418: 7417: 7414: 7413: 7410: 7409: 7407: 7406: 7400: 7398: 7394: 7393: 7391: 7390: 7385: 7380: 7375: 7369: 7367: 7356: 7355: 7353: 7352: 7347: 7342: 7337: 7332: 7327: 7322: 7317: 7312: 7307: 7302: 7297: 7292: 7287: 7282: 7280:Imipraminoxide 7277: 7272: 7267: 7262: 7257: 7252: 7247: 7242: 7237: 7232: 7227: 7222: 7217: 7211: 7209: 7194: 7193: 7177: 7176: 7173: 7172: 7169: 7168: 7166: 7165: 7160: 7155: 7150: 7145: 7140: 7135: 7130: 7125: 7120: 7115: 7110: 7105: 7100: 7095: 7090: 7084: 7082: 7078: 7077: 7075: 7074: 7069: 7063: 7061: 7050: 7049: 7047: 7046: 7041: 7036: 7030: 7028: 7017: 7016: 7014: 7013: 7008: 7003: 6997: 6995: 6984: 6983: 6981: 6980: 6975: 6970: 6964: 6962: 6951: 6950: 6948: 6947: 6942: 6937: 6931: 6929: 6918: 6917: 6915: 6914: 6909: 6904: 6899: 6894: 6889: 6887:Desvenlafaxine 6883: 6881: 6870: 6869: 6867: 6866: 6861: 6856: 6851: 6846: 6841: 6836: 6831: 6825: 6823: 6808: 6807: 6790: 6789: 6777: 6776: 6769: 6762: 6754: 6745: 6744: 6742: 6741: 6735: 6729: 6723: 6717: 6711: 6705: 6699: 6693: 6690:Norepinephrine 6687: 6681: 6675: 6669: 6664: 6659: 6654: 6647: 6645: 6641: 6640: 6638: 6637: 6632: 6626: 6624: 6620: 6619: 6617: 6616: 6611: 6606: 6601: 6596: 6591: 6586: 6581: 6576: 6571: 6566: 6560: 6558: 6552: 6551: 6549: 6548: 6543: 6537: 6535: 6526: 6521: 6520: 6518: 6517: 6512: 6507: 6502: 6496: 6494: 6483: 6482: 6480: 6479: 6469: 6464: 6459: 6454: 6431: 6429: 6415: 6414: 6404: 6403: 6396: 6389: 6381: 6374: 6373: 6333: 6331: 6328: 6325: 6324: 6297: 6270:(6): 476–481. 6254: 6224: 6181: 6174: 6156: 6125:(4): 455–466. 6105: 6068: 6044: 6022: 5996: 5962: 5955: 5929: 5910: 5891: 5884: 5858: 5831:(6): 571–590. 5815: 5768: 5732: 5678: 5643: 5594: 5543: 5499: 5466:Brain Research 5453: 5424:(2): 283–291. 5401: 5390:(1): 139–143. 5374: 5326: 5305:(1): 259–270. 5282: 5263:(3): 245–268. 5247: 5226:(5): 699–711. 5201: 5158: 5109: 5085: 5071: 5026: 4997:(2): 226–236. 4977: 4928: 4872: 4851:(2): 198–207. 4831: 4787: 4753: 4707: 4678:(2): 214–232. 4658: 4639:(4): 209–211. 4622: 4577: 4539: 4477: 4439: 4402: 4363:(4): 519–531. 4343: 4294: 4250: 4221:(9): 605–613. 4201: 4165: 4136:(6): 629–645. 4116: 4087:(6): 629–645. 4067: 4024: 4017: 3999: 3945: 3916:(3): 204–211. 3893: 3874:(9): 952–961. 3857: 3838:(1): 259–270. 3821: 3791: 3761: 3725: 3695: 3665: 3619: 3586: 3579: 3559: 3520:(5): 444–458. 3497: 3458:(8): 674–683. 3435: 3391: 3354:BMC Psychiatry 3337: 3301: 3252: 3216: 3183: 3154:(3): 179–193. 3131: 3102:(9): 605–613. 3082: 3053:(6): 629–645. 3033: 2997: 2952: 2912: 2885:(6): 571–590. 2830: 2789: 2736: 2695: 2659: 2618: 2588: 2554: 2525: 2494: 2493: 2491: 2488: 2468: 2465: 2455: 2452: 2439: 2436: 2411: 2408: 2402: 2399: 2386: 2383: 2382: 2381: 2378: 2371: 2369: 2366: 2359: 2348: 2345: 2333: 2330: 2282: 2277: 2247: 2231: 2216: 2213: 2192: 2185: 2178: 2171: 2164: 2154: 2122: 2110: 2103: 2073:rhesus monkeys 2044:levels in the 2021: 2020: 2012: 2008: 2007: 2004: 2001: 1998: 1992: 1991: 1986: 1981: 1978: 1973: 1968: 1967: 1962: 1957: 1954: 1949: 1944: 1943: 1938: 1933: 1930: 1925: 1920: 1919: 1916: 1913: 1910: 1906: 1901: 1900: 1897: 1894: 1891: 1887: 1882: 1881: 1878: 1875: 1872: 1868: 1863: 1862: 1859: 1856: 1853: 1849: 1844: 1843: 1840: 1837: 1834: 1830: 1825: 1824: 1821: 1818: 1815: 1811: 1806: 1805: 1802: 1799: 1796: 1792: 1787: 1786: 1783: 1780: 1777: 1773: 1768: 1767: 1762: 1757: 1754: 1750: 1745: 1744: 1739: 1734: 1731: 1727: 1722: 1721: 1718: 1715: 1712: 1708: 1703: 1702: 1697: 1692: 1689: 1685: 1680: 1679: 1674: 1669: 1666: 1662: 1657: 1656: 1651: 1646: 1643: 1639: 1634: 1633: 1630: 1629: 1624: 1619: 1614: 1606: 1605: 1602: 1599: 1594: 1589: 1583: 1582: 1577: 1572: 1569: 1565: 1560: 1559: 1554: 1548: 1545: 1532: 1531: 1526: 1520: 1515: 1504: 1503: 1498: 1492: 1489: 1476: 1475: 1470: 1465: 1462: 1456: 1455: 1450: 1445: 1440: 1427: 1426: 1421: 1416: 1411: 1398: 1397: 1392: 1387: 1382: 1372: 1369: 1367: 1364: 1363: 1362: 1332: 1327: 1307: 1298: 1280: 1253: 1216: 1213: 1208: 1205: 1156: 1153: 1152: 1151: 1145: 1139: 1134: 1131: 1128: 1127: 1126: 1120: 1115: 1110: 1105: 1103:Atrial flutter 1100: 1095: 1081: 1078: 1025: 1022: 1001: 998: 996: 993: 974: 937: 934: 925: 922: 865:used to treat 847: 846: 829: 828: 826: 825: 822: 820: 817: 809: 808: 807: 804: 803: 801: 800: 797: 789: 788: 787: 784: 783: 781: 780: 772: 770: 762: 761: 755: 749: 748: 739: 733: 728: 722: 721: 717: 716: 706: 698: 697: 695: 694: 681: 679: 666: 665: 663: 662: 654: 646: 644: 638: 637: 635: 634: 626: 618: 616: 610: 609: 607: 606: 598: 590: 588: 582: 581: 579: 578: 570: 562: 560: 554: 553: 551: 550: 542: 534: 532: 526: 525: 523: 522: 514: 506: 504: 498: 497: 495: 494: 486: 484: 478: 477: 475: 474: 466: 458: 456: 445: 444: 442: 441: 433: 425: 423: 417: 416: 414: 413: 402: 394: 393: 392: 389: 388: 384: 383: 377: 371: 370: 367: 358: 357: 348: 342: 341: 338: 332: 331: 328: 322: 321: 314: 313: 311: 310: 301: 286: 273: 262: 249: 235: 233: 227: 226: 222: 221: 219: 218: 205: 203: 197: 196: 191: 185: 184: 178: 176:administration 170: 169: 167: 166: 164: 154: 152: 144: 143: 141: 140: 122: 120: 114: 113: 106: 100: 99: 92: 82: 81: 66: 62: 61: 55: 49: 48: 44: 43: 35: 34: 15: 9: 6: 4: 3: 2: 19735: 19724: 19721: 19719: 19716: 19714: 19711: 19709: 19706: 19704: 19703:Phenol ethers 19701: 19699: 19696: 19694: 19691: 19689: 19686: 19684: 19681: 19679: 19676: 19674: 19671: 19669: 19666: 19665: 19663: 19653: 19643: 19642: 19639: 19619: 19616: 19613: 19612: 19609: 19606: 19604: 19603:Pronociceptin 19601: 19599: 19598:Proenkephalin 19596: 19594: 19591: 19589: 19586: 19583: 19582: 19579: 19576: 19574: 19571: 19569: 19566: 19564: 19561: 19559: 19556: 19554: 19551: 19549: 19546: 19544: 19541: 19539: 19536: 19534: 19531: 19529: 19526: 19524: 19521: 19519: 19516: 19514: 19511: 19509: 19503: 19501: 19498: 19496: 19493: 19491: 19488: 19486: 19482: 19481: 19479: 19475: 19465: 19462: 19460: 19457: 19455: 19452: 19450: 19447: 19445: 19442: 19440: 19437: 19435: 19432: 19430: 19427: 19425: 19422: 19420: 19417: 19415: 19412: 19410: 19407: 19405: 19402: 19400: 19394: 19393: 19391: 19387: 19381: 19378: 19376: 19373: 19371: 19368: 19366: 19363: 19361: 19358: 19356: 19353: 19351: 19348: 19346: 19343: 19341: 19338: 19336: 19333: 19331: 19328: 19326: 19320: 19318: 19315: 19313: 19310: 19308: 19305: 19303: 19300: 19298: 19295: 19293: 19290: 19288: 19285: 19283: 19280: 19278: 19275: 19273: 19270: 19268: 19265: 19263: 19260: 19258: 19257:Buprenorphine 19255: 19253: 19250: 19248: 19242: 19240: 19234: 19232: 19222: 19220: 19214: 19212: 19209: 19208: 19206: 19202: 19199: 19195: 19191: 19181: 19178: 19176: 19173: 19171: 19168: 19166: 19163: 19161: 19158: 19156: 19153: 19151: 19148: 19146: 19143: 19141: 19138: 19136: 19133: 19131: 19128: 19126: 19123: 19121: 19118: 19116: 19113: 19111: 19108: 19106: 19103: 19101: 19098: 19096: 19093: 19091: 19088: 19086: 19083: 19081: 19078: 19076: 19073: 19071: 19068: 19066: 19063: 19061: 19058: 19056: 19053: 19051: 19048: 19046: 19043: 19041: 19038: 19036: 19033: 19031: 19028: 19026: 19023: 19021: 19018: 19016: 19013: 19011: 19008: 19006: 19003: 19001: 18998: 18996: 18993: 18991: 18990:Buprenorphine 18988: 18986: 18983: 18981: 18978: 18976: 18973: 18971: 18968: 18966: 18963: 18961: 18958: 18956: 18953: 18951: 18948: 18946: 18943: 18941: 18940:Amentoflavone 18938: 18936: 18933: 18931: 18928: 18926: 18923: 18921: 18918: 18916: 18913: 18911: 18908: 18906: 18903: 18901: 18898: 18897: 18895: 18891: 18885: 18882: 18880: 18877: 18875: 18872: 18870: 18867: 18864: 18863:nortriptyline 18860: 18856: 18852: 18851:amitriptyline 18848: 18845: 18843: 18840: 18838: 18835: 18833: 18830: 18828: 18825: 18823: 18820: 18818: 18815: 18813: 18810: 18807: 18803: 18800: 18798: 18795: 18793: 18790: 18788: 18785: 18783: 18780: 18778: 18775: 18773: 18770: 18768: 18765: 18763: 18760: 18758: 18755: 18753: 18750: 18748: 18745: 18743: 18740: 18738: 18735: 18733: 18730: 18728: 18725: 18723: 18720: 18718: 18715: 18713: 18710: 18708: 18705: 18703: 18700: 18698: 18695: 18693: 18690: 18688: 18685: 18683: 18680: 18678: 18675: 18673: 18670: 18668: 18665: 18663: 18660: 18658: 18655: 18653: 18650: 18648: 18645: 18643: 18640: 18638: 18635: 18633: 18630: 18628: 18625: 18623: 18620: 18618: 18615: 18613: 18610: 18608: 18605: 18603: 18600: 18598: 18595: 18593: 18590: 18588: 18585: 18583: 18580: 18578: 18575: 18573: 18570: 18568: 18565: 18563: 18560: 18558: 18557:Hydromorphone 18555: 18553: 18550: 18548: 18545: 18543: 18540: 18538: 18535: 18533: 18530: 18528: 18525: 18523: 18520: 18518: 18515: 18513: 18510: 18508: 18505: 18503: 18500: 18498: 18495: 18493: 18490: 18488: 18485: 18483: 18480: 18478: 18475: 18473: 18472:Diprenorphine 18470: 18468: 18465: 18463: 18460: 18458: 18455: 18453: 18452:Difelikefalin 18450: 18448: 18445: 18443: 18440: 18438: 18435: 18433: 18432:Cyprenorphine 18430: 18428: 18425: 18423: 18420: 18418: 18415: 18413: 18410: 18408: 18405: 18403: 18400: 18398: 18395: 18393: 18390: 18388: 18385: 18383: 18380: 18378: 18377:Big dynorphin 18375: 18373: 18370: 18368: 18365: 18363: 18360: 18358: 18355: 18353: 18350: 18348: 18345: 18343: 18340: 18338: 18335: 18333: 18330: 18328: 18325: 18323: 18320: 18318: 18315: 18313: 18310: 18308: 18305: 18303: 18300: 18298: 18297:3CS-nalmefene 18295: 18294: 18292: 18288: 18285: 18281: 18277: 18267: 18264: 18262: 18259: 18257: 18254: 18252: 18249: 18247: 18244: 18242: 18239: 18237: 18234: 18232: 18229: 18227: 18224: 18222: 18219: 18217: 18214: 18212: 18209: 18207: 18204: 18202: 18199: 18197: 18194: 18192: 18189: 18187: 18184: 18182: 18179: 18177: 18174: 18172: 18169: 18167: 18164: 18162: 18159: 18157: 18154: 18152: 18149: 18147: 18144: 18142: 18141:Diprenorphine 18139: 18137: 18134: 18132: 18129: 18127: 18124: 18122: 18119: 18117: 18114: 18112: 18109: 18107: 18104: 18102: 18099: 18097: 18094: 18092: 18089: 18087: 18084: 18082: 18079: 18077: 18074: 18072: 18069: 18067: 18064: 18063: 18061: 18057: 18051: 18048: 18046: 18043: 18041: 18038: 18036: 18033: 18031: 18028: 18026: 18023: 18021: 18018: 18016: 18013: 18011: 18008: 18006: 18003: 18001: 17998: 17996: 17993: 17991: 17988: 17986: 17983: 17981: 17978: 17976: 17973: 17971: 17968: 17966: 17963: 17961: 17958: 17956: 17953: 17951: 17948: 17946: 17943: 17941: 17938: 17936: 17933: 17931: 17928: 17926: 17923: 17921: 17918: 17916: 17913: 17911: 17908: 17906: 17903: 17901: 17898: 17896: 17893: 17891: 17888: 17886: 17883: 17881: 17878: 17876: 17873: 17871: 17868: 17866: 17863: 17861: 17858: 17856: 17853: 17851: 17848: 17846: 17845:Hydromorphone 17843: 17841: 17838: 17836: 17833: 17831: 17828: 17826: 17823: 17821: 17818: 17816: 17813: 17811: 17808: 17806: 17803: 17801: 17798: 17796: 17793: 17791: 17788: 17786: 17783: 17781: 17778: 17776: 17773: 17771: 17768: 17766: 17763: 17761: 17758: 17756: 17755:Deltorphin II 17753: 17751: 17748: 17746: 17743: 17741: 17738: 17736: 17733: 17731: 17728: 17726: 17723: 17721: 17718: 17716: 17713: 17711: 17708: 17706: 17703: 17701: 17698: 17696: 17693: 17691: 17688: 17686: 17683: 17681: 17678: 17676: 17673: 17671: 17668: 17666: 17663: 17661: 17658: 17656: 17653: 17651: 17648: 17646: 17643: 17641: 17640:3CS-nalmefene 17638: 17637: 17635: 17631: 17628: 17624: 17620: 17610: 17607: 17605: 17602: 17600: 17597: 17595: 17592: 17590: 17587: 17585: 17582: 17580: 17577: 17575: 17572: 17570: 17567: 17565: 17562: 17560: 17557: 17555: 17552: 17550: 17547: 17545: 17542: 17540: 17537: 17535: 17532: 17530: 17527: 17525: 17522: 17520: 17517: 17515: 17512: 17510: 17507: 17505: 17502: 17500: 17497: 17495: 17492: 17490: 17489:Methocinnamox 17487: 17485: 17482: 17480: 17477: 17475: 17472: 17470: 17467: 17465: 17462: 17460: 17457: 17455: 17452: 17450: 17449:Ginsenoside R 17447: 17445: 17442: 17440: 17437: 17435: 17432: 17430: 17427: 17425: 17422: 17420: 17419:Diprenorphine 17417: 17415: 17412: 17410: 17407: 17405: 17402: 17400: 17397: 17394: 17392: 17389: 17387: 17384: 17382: 17379: 17377: 17374: 17372: 17369: 17367: 17364: 17362: 17359: 17357: 17354: 17352: 17349: 17347: 17344: 17342: 17339: 17337: 17334: 17332: 17329: 17327: 17324: 17322: 17319: 17317: 17314: 17312: 17309: 17307: 17304: 17302: 17299: 17297: 17296:3CS-nalmefene 17294: 17292: 17289: 17287: 17284: 17283: 17281: 17277: 17271: 17268: 17266: 17263: 17261: 17258: 17256: 17253: 17251: 17248: 17246: 17243: 17241: 17238: 17236: 17233: 17231: 17228: 17226: 17223: 17221: 17218: 17216: 17213: 17211: 17208: 17206: 17203: 17201: 17198: 17196: 17193: 17191: 17188: 17186: 17183: 17181: 17178: 17176: 17173: 17171: 17168: 17166: 17163: 17161: 17158: 17156: 17153: 17151: 17148: 17146: 17143: 17141: 17138: 17136: 17133: 17131: 17128: 17126: 17125:Phencyclidine 17123: 17121: 17118: 17116: 17113: 17111: 17108: 17106: 17103: 17100: 17096: 17095: 17091: 17089: 17086: 17084: 17081: 17079: 17076: 17074: 17071: 17069: 17068:Oxymorphazone 17066: 17064: 17061: 17059: 17056: 17054: 17051: 17049: 17046: 17044: 17041: 17039: 17036: 17034: 17031: 17029: 17026: 17024: 17021: 17019: 17016: 17014: 17011: 17009: 17006: 17004: 17001: 16999: 16996: 16994: 16991: 16989: 16986: 16984: 16981: 16979: 16976: 16974: 16971: 16969: 16966: 16964: 16961: 16959: 16956: 16954: 16951: 16949: 16946: 16944: 16941: 16939: 16936: 16934: 16931: 16929: 16926: 16924: 16921: 16919: 16916: 16914: 16911: 16909: 16906: 16904: 16901: 16899: 16896: 16894: 16891: 16889: 16886: 16884: 16881: 16879: 16876: 16874: 16871: 16869: 16866: 16864: 16861: 16859: 16858:Hydromorphone 16856: 16854: 16851: 16849: 16846: 16844: 16841: 16839: 16836: 16834: 16831: 16829: 16826: 16824: 16821: 16819: 16816: 16814: 16811: 16809: 16806: 16804: 16803:Ethylmorphine 16801: 16799: 16796: 16794: 16793:Endomorphin-2 16791: 16789: 16788:Endomorphin-1 16786: 16784: 16781: 16779: 16776: 16774: 16771: 16769: 16768:Diphenoxylate 16766: 16764: 16761: 16759: 16756: 16754: 16751: 16749: 16746: 16744: 16741: 16739: 16736: 16734: 16731: 16729: 16726: 16724: 16721: 16719: 16716: 16714: 16711: 16709: 16706: 16704: 16701: 16699: 16696: 16694: 16691: 16689: 16686: 16684: 16681: 16679: 16676: 16674: 16671: 16669: 16666: 16664: 16661: 16659: 16656: 16654: 16653:Butyrfentanyl 16651: 16649: 16646: 16644: 16641: 16639: 16638:Buprenorphine 16636: 16634: 16631: 16629: 16626: 16624: 16621: 16619: 16616: 16614: 16611: 16609: 16606: 16604: 16601: 16599: 16596: 16594: 16591: 16589: 16586: 16584: 16581: 16579: 16576: 16574: 16571: 16569: 16566: 16564: 16561: 16559: 16556: 16554: 16553:Acrylfentanyl 16551: 16549: 16546: 16544: 16541: 16539: 16536: 16534: 16531: 16529: 16528:ψ-Akuammigine 16526: 16524: 16521: 16519: 16516: 16514: 16511: 16510: 16508: 16505: 16497: 16494: 16490: 16486: 16482: 16479: 16472: 16467: 16465: 16460: 16458: 16453: 16452: 16449: 16438: 16437: 16433: 16429: 16428:Serotonergics 16425: 16424:Dopaminergics 16421: 16417: 16413: 16410: 16403: 16397: 16394: 16390: 16387: 16385: 16382: 16381:Agonist-like: 16379: 16376: 16375: 16372: 16369: 16366: 16365: 16363: 16359: 16353: 16350: 16348: 16345: 16343: 16342:Tetrabenazine 16340: 16338: 16335: 16333: 16330: 16328: 16325: 16323: 16320: 16318: 16315: 16313: 16310: 16308: 16305: 16303: 16300: 16298: 16295: 16293: 16290: 16288: 16285: 16283: 16280: 16278: 16275: 16273: 16270: 16268: 16265: 16262: 16258: 16254: 16250: 16247: 16245: 16242: 16241: 16239: 16234: 16228: 16218: 16215: 16212: 16208: 16204: 16200: 16196: 16192: 16188: 16185: 16183: 16180: 16178: 16175: 16173: 16170: 16168: 16165: 16163: 16160: 16158: 16155: 16153: 16150: 16148: 16145: 16143: 16140: 16138: 16135: 16133: 16130: 16127: 16126:phencyclidine 16123: 16122:methoxetamine 16119: 16115: 16111: 16107: 16104: 16101: 16097: 16093: 16090: 16087: 16083: 16079: 16075: 16071: 16067: 16063: 16059: 16056: 16054: 16051: 16049: 16046: 16043: 16042: 16039: 16033: 16032:Protriptyline 16030: 16028: 16025: 16023: 16022:Nortriptyline 16020: 16018: 16015: 16013: 16010: 16008: 16005: 16003: 16000: 15998: 15995: 15993: 15990: 15988: 15985: 15983: 15980: 15978: 15977:Amitriptyline 15975: 15972: 15971: 15968: 15961: 15957: 15954: 15952: 15949: 15947: 15944: 15942: 15941:Tedatioxetine 15939: 15937: 15934: 15932: 15929: 15927: 15924: 15922: 15919: 15917: 15914: 15912: 15909: 15907: 15904: 15902: 15899: 15897: 15894: 15892: 15889: 15887: 15884: 15882: 15879: 15877: 15874: 15872: 15869: 15867: 15864: 15862: 15859: 15857: 15854: 15852: 15849: 15847: 15844: 15842: 15839: 15837: 15834: 15832: 15829: 15827: 15824: 15822: 15819: 15817: 15814: 15812: 15809: 15807: 15804: 15802: 15801:Centanafadine 15799: 15797: 15794: 15792: 15789: 15787: 15784: 15782: 15779: 15777: 15774: 15771: 15770: 15767: 15761: 15758: 15756: 15753: 15751: 15748: 15746: 15745:N-Methyl-PPPA 15743: 15741: 15738: 15736: 15733: 15731: 15728: 15726: 15723: 15721: 15718: 15716: 15713: 15711: 15708: 15706: 15703: 15701: 15698: 15695: 15694: 15691: 15685: 15682: 15680: 15677: 15675: 15672: 15670: 15667: 15665: 15662: 15660: 15657: 15655: 15652: 15650: 15647: 15645: 15642: 15640: 15637: 15634: 15633: 15630: 15627: 15625: 15622: 15620: 15617: 15615: 15612: 15610: 15607: 15605: 15602: 15600: 15597: 15595: 15592: 15590: 15587: 15585: 15584:Norfluoxetine 15582: 15580: 15577: 15575: 15572: 15570: 15567: 15565: 15562: 15560: 15557: 15555: 15552: 15550: 15547: 15545: 15542: 15540: 15537: 15535: 15532: 15530: 15527: 15525: 15524:Centpropazine 15522: 15520: 15517: 15515: 15512: 15509: 15508: 15505: 15502: 15495: 15484: 15478: 15467: 15463: 15459: 15455: 15451: 15447: 15446:desmetramadol 15443: 15440: 15438: 15435: 15433: 15430: 15428: 15427: 15426:Ginkgo biloba 15423: 15421: 15418: 15416: 15413: 15410: 15409:phencyclidine 15406: 15402: 15399: 15396: 15392: 15388: 15385: 15382: 15378: 15374: 15370: 15366: 15363: 15360: 15359: 15356: 15350: 15347: 15345: 15342: 15340: 15337: 15335: 15332: 15330: 15327: 15324: 15323: 15320: 15314: 15311: 15309: 15308:Protriptyline 15306: 15304: 15303:Nortriptyline 15301: 15299: 15296: 15294: 15291: 15289: 15286: 15284: 15281: 15279: 15276: 15274: 15271: 15269: 15266: 15264: 15261: 15259: 15256: 15254: 15253:Amitriptyline 15251: 15248: 15247: 15244: 15237: 15233: 15230: 15228: 15225: 15223: 15220: 15218: 15217:Tedatioxetine 15215: 15213: 15210: 15208: 15205: 15203: 15200: 15198: 15195: 15193: 15190: 15188: 15185: 15183: 15180: 15178: 15175: 15173: 15170: 15168: 15165: 15163: 15160: 15158: 15155: 15153: 15150: 15148: 15145: 15143: 15140: 15138: 15135: 15133: 15130: 15128: 15125: 15123: 15120: 15118: 15115: 15113: 15110: 15108: 15105: 15103: 15100: 15098: 15095: 15093: 15090: 15088: 15085: 15083: 15080: 15078: 15077:Centanafadine 15075: 15073: 15070: 15068: 15065: 15063: 15060: 15058: 15055: 15053: 15050: 15047: 15046: 15043: 15037: 15034: 15032: 15029: 15027: 15024: 15022: 15019: 15017: 15016:N-Methyl-PPPA 15014: 15012: 15009: 15007: 15004: 15002: 14999: 14997: 14994: 14992: 14989: 14987: 14984: 14982: 14979: 14977: 14974: 14971: 14970: 14967: 14961: 14958: 14956: 14953: 14951: 14948: 14946: 14943: 14941: 14938: 14936: 14933: 14931: 14928: 14926: 14923: 14921: 14918: 14916: 14913: 14911: 14908: 14906: 14903: 14901: 14898: 14896: 14893: 14891: 14888: 14885: 14884: 14881: 14875: 14872: 14870: 14867: 14865: 14862: 14860: 14857: 14855: 14852: 14850: 14847: 14845: 14842: 14840: 14837: 14835: 14832: 14830: 14827: 14825: 14822: 14820: 14817: 14815: 14812: 14810: 14807: 14805: 14802: 14799: 14798: 14795: 14792: 14785: 14774: 14768: 14758: 14755: 14753: 14750: 14748: 14745: 14743: 14742:Tedatioxetine 14740: 14738: 14735: 14733: 14730: 14728: 14725: 14723: 14720: 14718: 14715: 14713: 14710: 14708: 14705: 14703: 14700: 14698: 14695: 14693: 14690: 14688: 14685: 14683: 14680: 14678: 14675: 14673: 14670: 14668: 14665: 14663: 14660: 14658: 14655: 14653: 14650: 14648: 14645: 14643: 14640: 14638: 14635: 14633: 14630: 14628: 14625: 14623: 14620: 14618: 14615: 14613: 14610: 14608: 14605: 14603: 14600: 14598: 14595: 14593: 14590: 14588: 14585: 14583: 14580: 14578: 14575: 14573: 14570: 14568: 14565: 14563: 14560: 14558: 14555: 14553: 14550: 14548: 14545: 14543: 14540: 14538: 14535: 14533: 14530: 14528: 14525: 14523: 14520: 14518: 14515: 14513: 14510: 14508: 14507: 14503: 14501: 14498: 14496: 14493: 14491: 14488: 14486: 14483: 14481: 14478: 14476: 14473: 14471: 14468: 14466: 14463: 14461: 14458: 14455: 14454: 14451: 14445: 14442: 14440: 14437: 14435: 14432: 14430: 14427: 14425: 14422: 14420: 14417: 14415: 14412: 14410: 14407: 14405: 14402: 14400: 14397: 14395: 14392: 14390: 14387: 14385: 14382: 14380: 14377: 14375: 14372: 14370: 14367: 14365: 14364:Ioflupane (I) 14362: 14360: 14357: 14355: 14352: 14350: 14347: 14345: 14342: 14340: 14337: 14335: 14332: 14330: 14327: 14325: 14322: 14320: 14317: 14315: 14312: 14309: 14308: 14305: 14299: 14296: 14294: 14291: 14289: 14286: 14284: 14281: 14279: 14276: 14275:Pyrrolidines: 14273: 14272: 14269: 14263: 14262:Tenocyclidine 14260: 14258: 14255: 14253: 14250: 14248: 14247:Phencyclidine 14245: 14243: 14240: 14238: 14235: 14233: 14230: 14228: 14225: 14223: 14220: 14218: 14215: 14213: 14210: 14208: 14205: 14203: 14200: 14197: 14196: 14193: 14187: 14184: 14182: 14179: 14177: 14174: 14172: 14169: 14167: 14164: 14162: 14159: 14157: 14154: 14152: 14149: 14146: 14145: 14142: 14139: 14132: 14121: 14115: 14111: 14104: 14099: 14097: 14092: 14090: 14085: 14084: 14081: 14071: 14070: 14066: 14063: 14057: 14046: 14042: 14041: 14039: 14034: 14028: 14021: 14017: 14016: 14014: 14009: 14003: 14000: 13996: 13982: 13979: 13977: 13974: 13972: 13969: 13967: 13966:Niflumic acid 13964: 13962: 13959: 13957: 13954: 13952: 13949: 13947: 13944: 13942: 13939: 13938: 13936: 13934: 13930: 13927: 13923: 13913: 13910: 13908: 13905: 13903: 13900: 13898: 13895: 13893: 13890: 13888: 13885: 13884: 13882: 13880: 13876: 13870: 13867: 13865: 13862: 13860: 13859:Glibenclamide 13857: 13856: 13854: 13852: 13848: 13845: 13840: 13834: 13824: 13821: 13820: 13818: 13816: 13812: 13806: 13805:Niflumic acid 13803: 13801: 13798: 13796: 13793: 13791: 13790:Glibenclamide 13788: 13786: 13783: 13781: 13778: 13776: 13773: 13771: 13768: 13766: 13763: 13761: 13758: 13757: 13755: 13753: 13749: 13746: 13741: 13735: 13732: 13730: 13726: 13712: 13709: 13707: 13704: 13702: 13699: 13697: 13694: 13692: 13689: 13688: 13686: 13684: 13680: 13677: 13672: 13666: 13656: 13653: 13652: 13650: 13648: 13644: 13638: 13635: 13633: 13630: 13628: 13625: 13624: 13622: 13620: 13616: 13613: 13608: 13602: 13592: 13589: 13587: 13586:Grayanotoxins 13584: 13582: 13579: 13577: 13576:Batrachotoxin 13574: 13571: 13567: 13563: 13562:ω-Atracotoxin 13559: 13557: 13554: 13553: 13551: 13549: 13545: 13539: 13536: 13534: 13531: 13528: 13524: 13521: 13519: 13516: 13514: 13513:Buprenorphine 13511: 13508: 13507: 13504: 13501: 13499: 13496: 13494: 13491: 13489: 13486: 13484: 13481: 13478: 13477: 13474: 13471: 13469: 13466: 13464: 13461: 13459: 13456: 13454: 13451: 13449: 13446: 13444: 13441: 13439: 13436: 13434: 13431: 13429: 13426: 13423: 13422: 13419: 13416: 13414: 13411: 13409: 13406: 13404: 13401: 13399: 13396: 13394: 13391: 13389: 13386: 13384: 13381: 13379: 13376: 13374: 13371: 13369: 13366: 13364: 13361: 13359: 13356: 13354: 13351: 13349: 13346: 13344: 13341: 13339: 13336: 13334: 13331: 13329: 13326: 13324: 13321: 13319: 13316: 13314: 13311: 13309: 13306: 13304: 13301: 13298: 13294: 13290: 13287: 13285: 13282: 13280: 13277: 13275: 13272: 13270: 13268: 13264: 13261: 13260: 13257: 13254: 13252: 13249: 13247: 13246:Valproic acid 13244: 13242: 13239: 13237: 13234: 13232: 13229: 13227: 13224: 13222: 13219: 13217: 13214: 13212: 13209: 13207: 13204: 13202: 13199: 13197: 13194: 13192: 13191:Oxitriptyline 13189: 13187: 13186:Oxcarbazepine 13184: 13182: 13179: 13177: 13176:Licarbazepine 13174: 13172: 13169: 13167: 13164: 13162: 13159: 13157: 13154: 13152: 13149: 13147: 13144: 13142: 13139: 13137: 13134: 13132: 13131:Carbamazepine 13129: 13127: 13124: 13121: 13120: 13117: 13114: 13112: 13109: 13107: 13104: 13102: 13099: 13097: 13094: 13092: 13089: 13087: 13084: 13082: 13079: 13077: 13074: 13072: 13069: 13067: 13064: 13062: 13059: 13057: 13054: 13052: 13049: 13047: 13044: 13042: 13039: 13037: 13034: 13032: 13029: 13026: 13025: 13022: 13019: 13018:Antianginals: 13016: 13015: 13013: 13011: 13007: 13004: 12999: 12993: 12990: 12988: 12984: 12970: 12967: 12966: 12964: 12962: 12958: 12952: 12951:Norfluoxetine 12949: 12947: 12944: 12942: 12939: 12937: 12934: 12933: 12931: 12929: 12925: 12922: 12917: 12911: 12901: 12898: 12896: 12893: 12891: 12888: 12886: 12885:Niflumic acid 12883: 12881: 12878: 12876: 12873: 12871: 12864: 12863: 12861: 12859: 12855: 12849: 12846: 12844: 12841: 12839: 12832: 12831: 12829: 12827: 12823: 12820: 12815: 12806: 12796: 12793: 12788: 12782: 12781: 12778: 12775: 12773: 12770: 12768: 12765: 12763: 12760: 12758: 12755: 12753: 12750: 12748: 12745: 12743: 12740: 12738: 12737:Levcromakalim 12735: 12733: 12730: 12728: 12725: 12723: 12720: 12718: 12715: 12713: 12710: 12705: 12696: 12695: 12693: 12691: 12687: 12681: 12678: 12676: 12673: 12671: 12668: 12666: 12663: 12661: 12658: 12656: 12653: 12651: 12648: 12646: 12643: 12641: 12638: 12633: 12627: 12626: 12623: 12620: 12618: 12615: 12613: 12610: 12608: 12605: 12603: 12600: 12598: 12595: 12593: 12590: 12588: 12585: 12583: 12580: 12578: 12575: 12573: 12570: 12568: 12565: 12563: 12560: 12558: 12555: 12553: 12550: 12548: 12545: 12543: 12540: 12538: 12535: 12533: 12532:Acetohexamide 12530: 12525: 12516: 12515: 12513: 12511: 12507: 12504: 12499: 12493: 12483: 12480: 12478: 12475: 12473: 12465: 12464: 12462: 12460: 12456: 12450: 12447: 12445: 12442: 12440: 12437: 12435: 12427: 12426: 12423: 12420: 12418: 12415: 12413: 12410: 12408: 12405: 12403: 12400: 12398: 12395: 12393: 12390: 12388: 12385: 12383: 12380: 12378: 12377:Roxithromycin 12375: 12373: 12370: 12368: 12365: 12363: 12360: 12358: 12355: 12353: 12350: 12348: 12345: 12343: 12340: 12338: 12335: 12333: 12330: 12328: 12325: 12323: 12320: 12318: 12315: 12313: 12310: 12308: 12305: 12303: 12300: 12298: 12295: 12293: 12290: 12288: 12285: 12283: 12280: 12278: 12275: 12273: 12270: 12268: 12265: 12263: 12260: 12258: 12255: 12253: 12250: 12248: 12245: 12243: 12240: 12238: 12235: 12233: 12230: 12228: 12225: 12223: 12220: 12214: 12210: 12209: 12206: 12203: 12201: 12198: 12196: 12193: 12191: 12188: 12186: 12183: 12181: 12178: 12176: 12173: 12171: 12168: 12166: 12163: 12161: 12158: 12156: 12153: 12151: 12148: 12146: 12143: 12141: 12138: 12136: 12133: 12131: 12128: 12126: 12123: 12121: 12118: 12116: 12113: 12111: 12108: 12106: 12103: 12101: 12098: 12096: 12093: 12091: 12088: 12086: 12083: 12081: 12078: 12076: 12073: 12071: 12070:Charybdotoxin 12068: 12066: 12063: 12061: 12058: 12056: 12053: 12051: 12048: 12046: 12043: 12041: 12038: 12036: 12033: 12031: 12028: 12027: 12025: 12023: 12019: 12016: 12011: 12005: 12002: 12000: 11996: 11982: 11979: 11977: 11973: 11972: 11970: 11968: 11964: 11958: 11955: 11953: 11952:Trimethadione 11950: 11948: 11945: 11943: 11940: 11938: 11935: 11933: 11930: 11928: 11925: 11923: 11920: 11918: 11915: 11913: 11910: 11908: 11905: 11903: 11900: 11898: 11895: 11893: 11890: 11888: 11885: 11883: 11880: 11878: 11875: 11873: 11870: 11868: 11865: 11863: 11860: 11858: 11855: 11853: 11850: 11848: 11845: 11843: 11840: 11838: 11835: 11833: 11830: 11828: 11825: 11823: 11820: 11818: 11815: 11813: 11810: 11808: 11805: 11803: 11800: 11798: 11795: 11793: 11792:Diproteverine 11790: 11788: 11785: 11783: 11780: 11778: 11775: 11773: 11770: 11768: 11765: 11763: 11760: 11758: 11755: 11753: 11750: 11747: 11746: 11743: 11740: 11738: 11735: 11733: 11730: 11728: 11725: 11723: 11720: 11718: 11715: 11713: 11710: 11708: 11705: 11703: 11700: 11698: 11695: 11693: 11690: 11688: 11685: 11683: 11680: 11678: 11675: 11673: 11669: 11661: 11660: 11657: 11654: 11652: 11651:Ruthenium red 11649: 11647: 11644: 11642: 11639: 11637: 11634: 11632: 11629: 11627: 11626:Levetiracetam 11624: 11622: 11619: 11617: 11614: 11612: 11609: 11607: 11604: 11602: 11599: 11597: 11594: 11592: 11589: 11587: 11584: 11582: 11579: 11577: 11576:ω-Agatoxin TK 11574: 11571: 11570: 11567: 11564: 11562: 11559: 11557: 11554: 11552: 11549: 11547: 11546:Niflumic acid 11544: 11542: 11539: 11537: 11534: 11532: 11528: 11527: 11524: 11521: 11519: 11515: 11514: 11511: 11508: 11506: 11503: 11501: 11497: 11496: 11493: 11490: 11488: 11485: 11483: 11480: 11478: 11475: 11473: 11470: 11468: 11465: 11463: 11460: 11458: 11455: 11453: 11450: 11448: 11445: 11443: 11439: 11438: 11435: 11432: 11430: 11427: 11425: 11422: 11420: 11417: 11415: 11412: 11410: 11407: 11405: 11402: 11400: 11397: 11395: 11392: 11388: 11385: 11383: 11380: 11378: 11375: 11373: 11370: 11368: 11365: 11363: 11360: 11358: 11355: 11353: 11350: 11348: 11345: 11343: 11340: 11338: 11335: 11333: 11330: 11328: 11325: 11323: 11320: 11318: 11313: 11310: 11308: 11305: 11303: 11300: 11298: 11295: 11293: 11290: 11288: 11283: 11280: 11278: 11275: 11273: 11270: 11268: 11265: 11263: 11260: 11258: 11255: 11253: 11250: 11248: 11245: 11243: 11240: 11238: 11235: 11233: 11230: 11228: 11225: 11223: 11220: 11218: 11215: 11213: 11210: 11208: 11205: 11203: 11200: 11198: 11195: 11193: 11190: 11188: 11185: 11183: 11180: 11178: 11175: 11173: 11170: 11168: 11167:Levamlodipine 11165: 11163: 11162:Lercanidipine 11160: 11158: 11155: 11153: 11150: 11148: 11145: 11143: 11140: 11138: 11135: 11133: 11130: 11128: 11125: 11123: 11120: 11118: 11115: 11113: 11110: 11108: 11105: 11103: 11100: 11098: 11095: 11093: 11090: 11088: 11085: 11083: 11080: 11078: 11075: 11073: 11069: 11067: 11063: 11062: 11060: 11058: 11054: 11051: 11046: 11040: 11037: 11035: 11031: 11027: 11020: 11015: 11013: 11008: 11006: 11001: 11000: 10997: 10981: 10980: 10976: 10972: 10969: 10963: 10953: 10950: 10948: 10945: 10943: 10940: 10938: 10935: 10933: 10930: 10928: 10925: 10922: 10921: 10918: 10915: 10911: 10905: 10903: 10900: 10898: 10895: 10892: 10891: 10889: 10884: 10875: 10869: 10866: 10862: 10859: 10857: 10854: 10852: 10849: 10847: 10844: 10842: 10839: 10837: 10834: 10832: 10829: 10827: 10824: 10821: 10820: 10817: 10814: 10812: 10806: 10804: 10801: 10799: 10796: 10793: 10792: 10790: 10785: 10776: 10770: 10767: 10765: 10762: 10760: 10757: 10755: 10752: 10750: 10747: 10745: 10742: 10739: 10738: 10735: 10729: 10727: 10724: 10721: 10720: 10718: 10713: 10704: 10698: 10695: 10693: 10690: 10688: 10685: 10683: 10680: 10678: 10675: 10673: 10670: 10667: 10666: 10663: 10660: 10658: 10655: 10651: 10648: 10646: 10643: 10641: 10638: 10636: 10633: 10631: 10625: 10623: 10620: 10617: 10616: 10614: 10609: 10600: 10597: 10595: 10591: 10581: 10578: 10576: 10573: 10569: 10566: 10564: 10561: 10559: 10556: 10554: 10551: 10549: 10546: 10544: 10541: 10539: 10536: 10534: 10531: 10528: 10527: 10524: 10521: 10519: 10516: 10514: 10511: 10509: 10506: 10504: 10501: 10499: 10496: 10494: 10493:Ibotenic acid 10491: 10489: 10486: 10484: 10481: 10479: 10476: 10474: 10471: 10468: 10467: 10465: 10460: 10451: 10445: 10442: 10440: 10437: 10433: 10430: 10428: 10425: 10423: 10420: 10418: 10415: 10413: 10410: 10408: 10405: 10403: 10400: 10398: 10395: 10393: 10390: 10387: 10386: 10383: 10380: 10376: 10373: 10371: 10368: 10366: 10363: 10361: 10358: 10356: 10353: 10351: 10348: 10346: 10343: 10341: 10340:Ibotenic acid 10338: 10336: 10333: 10331: 10328: 10326: 10323: 10321: 10318: 10316: 10313: 10310: 10309: 10307: 10302: 10293: 10290: 10288: 10284: 10274: 10271: 10269: 10266: 10264: 10261: 10259: 10256: 10254: 10251: 10249: 10246: 10244: 10241: 10239: 10236: 10232: 10229: 10227: 10224: 10222: 10219: 10217: 10214: 10212: 10209: 10207: 10204: 10202: 10199: 10197: 10194: 10192: 10189: 10186: 10185: 10182: 10179: 10175: 10172: 10170: 10167: 10165: 10164:Ibotenic acid 10162: 10160: 10157: 10155: 10152: 10150: 10147: 10145: 10142: 10140: 10137: 10135: 10132: 10130: 10127: 10124: 10123: 10121: 10116: 10107: 10101: 10098: 10096: 10093: 10091: 10088: 10086: 10083: 10081: 10080:Cyclothiazide 10078: 10076: 10073: 10071: 10068: 10065: 10064: 10061: 10058: 10056: 10053: 10051: 10048: 10046: 10043: 10041: 10038: 10036: 10033: 10031: 10030:Ibotenic acid 10028: 10026: 10023: 10021: 10018: 10016: 10013: 10010: 10009: 10007: 10002: 9993: 9990: 9988: 9984: 9980: 9977: 9970: 9965: 9963: 9958: 9956: 9951: 9950: 9947: 9935: 9934: 9930: 9928: 9927: 9923: 9921: 9920: 9917: 9913: 9912: 9909: 9903: 9900: 9897: 9894: 9893: 9889: 9885: 9884:Transcrocetin 9882: 9880: 9879:Psychotridine 9877: 9875: 9872: 9870: 9867: 9865: 9862: 9860: 9859:Niflumic acid 9857: 9855: 9852: 9850: 9847: 9845: 9842: 9840: 9837: 9835: 9832: 9830: 9827: 9825: 9822: 9820: 9817: 9815: 9812: 9810: 9807: 9805: 9802: 9800: 9797: 9795: 9789: 9787: 9784: 9782: 9779: 9777: 9774: 9772: 9769: 9765: 9762: 9760: 9757: 9755: 9752: 9750: 9747: 9745: 9742: 9740: 9737: 9735: 9732: 9730: 9727: 9725: 9722: 9720: 9719:Nitrous oxide 9717: 9715: 9712: 9710: 9707: 9705: 9702: 9700: 9697: 9695: 9692: 9690: 9687: 9685: 9684:Diethyl ether 9682: 9680: 9677: 9675: 9672: 9670: 9667: 9665: 9662: 9660: 9657: 9653: 9650: 9648: 9645: 9643: 9640: 9636: 9633: 9631: 9628: 9626: 9623: 9621: 9618: 9614: 9611: 9609: 9606: 9604: 9601: 9599: 9596: 9594: 9591: 9589: 9586: 9584: 9581: 9579: 9576: 9574: 9571: 9569: 9566: 9564: 9561: 9559: 9556: 9554: 9550: 9547: 9545: 9542: 9540: 9539:Tenocyclidine 9537: 9535: 9534:Tabernanthine 9532: 9530: 9527: 9525: 9524:Rolicyclidine 9522: 9520: 9517: 9515: 9512: 9510: 9507: 9505: 9502: 9500: 9499:Phencyclidine 9497: 9495: 9494:Phencyclamine 9492: 9490: 9487: 9485: 9482: 9480: 9477: 9475: 9472: 9470: 9467: 9465: 9462: 9460: 9457: 9455: 9452: 9450: 9447: 9445: 9442: 9440: 9437: 9435: 9432: 9430: 9429:Methoxetamine 9427: 9425: 9422: 9420: 9417: 9415: 9412: 9410: 9407: 9405: 9402: 9400: 9397: 9395: 9392: 9390: 9389:Levomethadone 9387: 9385: 9382: 9380: 9377: 9375: 9372: 9370: 9367: 9365: 9362: 9360: 9357: 9355: 9352: 9350: 9349:Fluorolintane 9347: 9345: 9342: 9340: 9337: 9335: 9332: 9330: 9327: 9325: 9322: 9320: 9317: 9315: 9312: 9310: 9307: 9305: 9302: 9300: 9297: 9295: 9292: 9290: 9287: 9285: 9282: 9280: 9277: 9275: 9272: 9270: 9267: 9265: 9262: 9260: 9257: 9255: 9252: 9250: 9247: 9245: 9242: 9240: 9237: 9235: 9232: 9230: 9227: 9225: 9222: 9220: 9217: 9215: 9212: 9210: 9207: 9205: 9202: 9200: 9197: 9195: 9192: 9190: 9187: 9185: 9182: 9178: 9175: 9173: 9170: 9168: 9165: 9163: 9160: 9158: 9155: 9153: 9150: 9146: 9143: 9141: 9138: 9136: 9133: 9131: 9128: 9126: 9123: 9121: 9118: 9116: 9113: 9111: 9108: 9106: 9103: 9101: 9098: 9096: 9093: 9091: 9088: 9086: 9083: 9081: 9078: 9076: 9073: 9071: 9068: 9066: 9063: 9061: 9055: 9053: 9050: 9048: 9045: 9043: 9040: 9038: 9035: 9033: 9030: 9028: 9025: 9023: 9020: 9018: 9015: 9013: 9010: 9008: 9005: 9003: 9000: 8996: 8993: 8991: 8988: 8986: 8983: 8981: 8978: 8976: 8973: 8971: 8968: 8966: 8963: 8961: 8958: 8956: 8953: 8951: 8948: 8946: 8943: 8941: 8938: 8936: 8933: 8931: 8930:Kaitocephalin 8928: 8926: 8923: 8921: 8918: 8916: 8913: 8911: 8908: 8906: 8903: 8901: 8898: 8896: 8893: 8891: 8888: 8885: 8882: 8881: 8878: 8875: 8873: 8870: 8868: 8865: 8863: 8860: 8858: 8855: 8853: 8850: 8847: 8843: 8837: 8834: 8827: 8822: 8820: 8818: 8813: 8809: 8806: 8804: 8801: 8799: 8796: 8792: 8789: 8787: 8784: 8782: 8779: 8777: 8774: 8772: 8766: 8764: 8758: 8756: 8753: 8751: 8748: 8746: 8743: 8741: 8738: 8736: 8733: 8731: 8725: 8723: 8717: 8715: 8709: 8707: 8704: 8702: 8699: 8697: 8694: 8692: 8689: 8687: 8684: 8682: 8679: 8677: 8674: 8672: 8665: 8661: 8658: 8656: 8653: 8651: 8648: 8646: 8643: 8641: 8638: 8636: 8635:Ibotenic acid 8633: 8631: 8628: 8626: 8619: 8617: 8614: 8612: 8609: 8607: 8604: 8601: 8598: 8597: 8595: 8590: 8584: 8578: 8575: 8573: 8570: 8568: 8565: 8563: 8560: 8558: 8555: 8552: 8548: 8547:pentobarbital 8544: 8541: 8537: 8534: 8532: 8529: 8527: 8524: 8522: 8519: 8517: 8514: 8512: 8509: 8507: 8504: 8502: 8499: 8497: 8494: 8492: 8489: 8487: 8486:Kaitocephalin 8484: 8482: 8479: 8477: 8474: 8472: 8469: 8467: 8464: 8462: 8459: 8456: 8455: 8452: 8449: 8447: 8444: 8442: 8439: 8437: 8434: 8432: 8431:Cyclothiazide 8429: 8425: 8422: 8420: 8417: 8415: 8412: 8410: 8407: 8405: 8402: 8400: 8399:Ibotenic acid 8397: 8395: 8392: 8390: 8387: 8385: 8382: 8380: 8377: 8375: 8372: 8370: 8367: 8365: 8362: 8359: 8356: 8355: 8353: 8348: 8342: 8336: 8333: 8329: 8326: 8324: 8321: 8319: 8316: 8314: 8311: 8309: 8306: 8304: 8301: 8299: 8296: 8294: 8291: 8289: 8286: 8284: 8281: 8279: 8276: 8274: 8271: 8269: 8266: 8263: 8259: 8258:pentobarbital 8255: 8252: 8248: 8245: 8243: 8240: 8238: 8235: 8233: 8230: 8228: 8225: 8223: 8220: 8218: 8215: 8213: 8210: 8208: 8205: 8203: 8200: 8198: 8195: 8193: 8192:Kaitocephalin 8190: 8188: 8185: 8183: 8180: 8178: 8175: 8173: 8170: 8168: 8165: 8163: 8160: 8158: 8155: 8153: 8150: 8148: 8145: 8142: 8141: 8138: 8135: 8133: 8130: 8128: 8125: 8123: 8120: 8118: 8115: 8113: 8110: 8108: 8105: 8103: 8100: 8098: 8095: 8093: 8090: 8088: 8085: 8083: 8080: 8078: 8075: 8073: 8070: 8068: 8065: 8063: 8060: 8058: 8055: 8053: 8050: 8048: 8045: 8043: 8040: 8038: 8035: 8033: 8030: 8028: 8025: 8023: 8020: 8018: 8015: 8013: 8012:Cyclothiazide 8010: 8008: 8005: 8001: 7998: 7996: 7993: 7991: 7988: 7986: 7985:Ibotenic acid 7983: 7981: 7978: 7976: 7973: 7971: 7968: 7966: 7963: 7961: 7958: 7956: 7953: 7950: 7947: 7946: 7944: 7939: 7933: 7929: 7926: 7919: 7914: 7912: 7907: 7905: 7900: 7899: 7896: 7890: 7886: 7883: 7878: 7872: 7868: 7863: 7847: 7845: 7842: 7841: 7839: 7836: 7833: 7830: 7828: 7825: 7824: 7820: 7810: 7807: 7805: 7802: 7800: 7793: 7791: 7789: 7785: 7782: 7778: 7774: 7773:neurosteroids 7771: 7768: 7766: 7759: 7758: 7755: 7751:Miscellaneous 7748: 7744: 7729: 7728:levothyroxine 7721: 7717: 7714: 7711: 7707: 7703: 7700: 7698: 7695: 7692: 7688: 7684: 7680: 7676: 7675:brexpiprazole 7672: 7668: 7665: 7664: 7661: 7657: 7652: 7648: 7634: 7631: 7630:Irreversible: 7628: 7627: 7625: 7619: 7610: 7604: 7601: 7599: 7596: 7594: 7591: 7589: 7586: 7584: 7581: 7579: 7576: 7574: 7571: 7568: 7567: 7565: 7559: 7550: 7544: 7541: 7538: 7537: 7534: 7531: 7528: 7527: 7524: 7521: 7519: 7516: 7514: 7511: 7509: 7506: 7504: 7501: 7499: 7496: 7494: 7491: 7489: 7486: 7484: 7481: 7479: 7476: 7474: 7471: 7469: 7466: 7464: 7463:Isocarboxazid 7461: 7459: 7456: 7454: 7451: 7449: 7446: 7445:Irreversible: 7443: 7442: 7440: 7438:Non-selective 7436: 7432: 7428: 7423: 7419: 7405: 7402: 7401: 7399: 7395: 7389: 7386: 7384: 7381: 7379: 7376: 7374: 7371: 7370: 7368: 7363: 7357: 7351: 7348: 7346: 7343: 7341: 7338: 7336: 7335:Protriptyline 7333: 7331: 7328: 7326: 7323: 7321: 7318: 7316: 7313: 7311: 7310:Nortriptyline 7308: 7306: 7305:Nitroxazepine 7303: 7301: 7298: 7296: 7293: 7291: 7288: 7286: 7283: 7281: 7278: 7276: 7273: 7271: 7268: 7266: 7263: 7261: 7258: 7256: 7253: 7251: 7248: 7246: 7245:Demexiptiline 7243: 7241: 7238: 7236: 7233: 7231: 7228: 7226: 7223: 7221: 7220:Amitriptyline 7218: 7216: 7213: 7212: 7210: 7205: 7199: 7195: 7191: 7187: 7182: 7178: 7164: 7161: 7159: 7156: 7154: 7151: 7149: 7146: 7144: 7141: 7139: 7136: 7134: 7131: 7129: 7126: 7124: 7121: 7119: 7116: 7114: 7111: 7109: 7106: 7104: 7101: 7099: 7096: 7094: 7091: 7089: 7086: 7085: 7083: 7079: 7073: 7070: 7068: 7065: 7064: 7062: 7057: 7051: 7045: 7042: 7040: 7037: 7035: 7032: 7031: 7029: 7024: 7018: 7012: 7009: 7007: 7004: 7002: 6999: 6998: 6996: 6991: 6985: 6979: 6976: 6974: 6971: 6969: 6966: 6965: 6963: 6958: 6952: 6946: 6943: 6941: 6938: 6936: 6933: 6932: 6930: 6925: 6919: 6913: 6910: 6908: 6905: 6903: 6900: 6898: 6895: 6893: 6890: 6888: 6885: 6884: 6882: 6877: 6871: 6865: 6862: 6860: 6857: 6855: 6852: 6850: 6847: 6845: 6842: 6840: 6837: 6835: 6832: 6830: 6827: 6826: 6824: 6819: 6813: 6809: 6805: 6801: 6795: 6791: 6786: 6782: 6775: 6770: 6768: 6763: 6761: 6756: 6755: 6752: 6739: 6736: 6733: 6730: 6727: 6724: 6721: 6718: 6715: 6712: 6709: 6706: 6703: 6700: 6697: 6694: 6691: 6688: 6685: 6682: 6679: 6676: 6673: 6670: 6668: 6665: 6663: 6660: 6658: 6655: 6652: 6649: 6648: 6646: 6642: 6636: 6635:Carbamazepine 6633: 6631: 6628: 6627: 6625: 6621: 6615: 6612: 6610: 6607: 6605: 6604:Nortriptyline 6602: 6600: 6597: 6595: 6592: 6590: 6587: 6585: 6582: 6580: 6577: 6575: 6572: 6570: 6567: 6565: 6564:Amitriptyline 6562: 6561: 6559: 6557: 6553: 6547: 6544: 6542: 6539: 6538: 6536: 6534: 6530: 6529:-adrenoceptor 6522: 6516: 6513: 6511: 6508: 6506: 6503: 6501: 6498: 6497: 6495: 6493: 6486:Non-classical 6484: 6477: 6473: 6470: 6468: 6465: 6463: 6460: 6458: 6455: 6452: 6448: 6444: 6440: 6436: 6433: 6432: 6430: 6428: 6422: 6416: 6412: 6402: 6397: 6395: 6390: 6388: 6383: 6382: 6379: 6362: 6358: 6354: 6350: 6346: 6345: 6340: 6335: 6334: 6320: 6316: 6312: 6308: 6301: 6293: 6289: 6285: 6281: 6277: 6273: 6269: 6265: 6258: 6251: 6244: 6237: 6236: 6228: 6220: 6216: 6212: 6208: 6204: 6200: 6196: 6192: 6185: 6177: 6175:9780071827706 6171: 6167: 6160: 6152: 6148: 6143: 6138: 6133: 6128: 6124: 6120: 6116: 6109: 6093: 6089: 6087: 6081: 6075: 6073: 6061: 6054: 6048: 6040: 6036: 6032: 6026: 6010: 6006: 6000: 5984: 5980: 5976: 5972: 5966: 5958: 5952: 5948: 5943: 5942: 5933: 5920: 5914: 5901: 5895: 5887: 5881: 5877: 5873: 5869: 5862: 5854: 5850: 5846: 5842: 5838: 5834: 5830: 5826: 5819: 5811: 5807: 5803: 5799: 5795: 5791: 5788:(1): 98–107. 5787: 5783: 5775: 5773: 5753: 5749: 5742: 5736: 5728: 5724: 5719: 5714: 5710: 5706: 5702: 5698: 5694: 5687: 5685: 5683: 5674: 5670: 5666: 5662: 5658: 5654: 5647: 5639: 5635: 5630: 5625: 5621: 5617: 5613: 5609: 5605: 5598: 5590: 5586: 5581: 5576: 5571: 5566: 5563:: 1433–1446. 5562: 5558: 5554: 5547: 5539: 5535: 5531: 5527: 5523: 5519: 5515: 5511: 5503: 5495: 5491: 5487: 5483: 5479: 5475: 5471: 5467: 5460: 5458: 5449: 5445: 5440: 5435: 5431: 5427: 5423: 5419: 5415: 5408: 5406: 5397: 5393: 5389: 5385: 5378: 5371: 5366: 5362: 5358: 5354: 5350: 5346: 5342: 5338: 5330: 5322: 5318: 5313: 5308: 5304: 5300: 5296: 5289: 5287: 5278: 5274: 5270: 5266: 5262: 5258: 5251: 5243: 5239: 5234: 5229: 5225: 5221: 5217: 5210: 5208: 5206: 5197: 5193: 5189: 5185: 5181: 5177: 5169: 5167: 5165: 5163: 5154: 5150: 5145: 5140: 5136: 5132: 5128: 5124: 5120: 5113: 5097: 5093: 5089: 5082:, Driscol J. 5081: 5075: 5056: 5052: 5050: 5041: 5035: 5033: 5031: 5022: 5018: 5013: 5008: 5004: 5000: 4996: 4992: 4988: 4981: 4973: 4969: 4965: 4961: 4956: 4951: 4947: 4943: 4939: 4932: 4924: 4920: 4915: 4910: 4905: 4900: 4896: 4892: 4888: 4881: 4879: 4877: 4868: 4864: 4859: 4854: 4850: 4846: 4842: 4835: 4827: 4823: 4819: 4815: 4811: 4807: 4803: 4799: 4791: 4775: 4771: 4767: 4763: 4757: 4741: 4737: 4733: 4729: 4725: 4721: 4720:NIHR Evidence 4717: 4711: 4703: 4699: 4694: 4689: 4685: 4681: 4677: 4673: 4669: 4662: 4654: 4650: 4646: 4642: 4638: 4634: 4626: 4618: 4614: 4609: 4604: 4600: 4596: 4592: 4588: 4581: 4574: 4570: 4566: 4562: 4558: 4554: 4550: 4543: 4535: 4531: 4527: 4523: 4518: 4513: 4508: 4503: 4499: 4495: 4491: 4484: 4482: 4473: 4469: 4465: 4461: 4457: 4453: 4446: 4444: 4424: 4420: 4413: 4406: 4390: 4386: 4382: 4378: 4374: 4370: 4366: 4362: 4358: 4354: 4347: 4339: 4335: 4330: 4325: 4321: 4317: 4313: 4309: 4305: 4298: 4290: 4286: 4282: 4278: 4274: 4270: 4266: 4262: 4254: 4246: 4242: 4237: 4232: 4228: 4224: 4220: 4216: 4212: 4205: 4197: 4193: 4189: 4185: 4181: 4177: 4169: 4161: 4157: 4152: 4147: 4143: 4139: 4135: 4131: 4127: 4120: 4112: 4108: 4103: 4098: 4094: 4090: 4086: 4082: 4078: 4071: 4063: 4059: 4055: 4051: 4047: 4043: 4039: 4035: 4028: 4020: 4014: 4010: 4003: 3995: 3991: 3986: 3981: 3976: 3971: 3967: 3963: 3959: 3952: 3950: 3941: 3937: 3933: 3929: 3924: 3919: 3915: 3911: 3907: 3900: 3898: 3889: 3885: 3881: 3877: 3873: 3869: 3861: 3853: 3849: 3845: 3841: 3837: 3833: 3825: 3809: 3805: 3801: 3795: 3779: 3775: 3771: 3765: 3757: 3753: 3749: 3745: 3741: 3737: 3729: 3713: 3709: 3705: 3699: 3683: 3679: 3675: 3669: 3661: 3657: 3653: 3649: 3645: 3641: 3637: 3633: 3626: 3624: 3607: 3603: 3599: 3593: 3591: 3582: 3580:9780857113382 3576: 3572: 3566: 3564: 3547: 3543: 3539: 3535: 3531: 3527: 3523: 3519: 3515: 3511: 3504: 3502: 3485: 3481: 3477: 3473: 3469: 3465: 3461: 3457: 3453: 3449: 3442: 3440: 3431: 3427: 3422: 3417: 3413: 3409: 3405: 3398: 3396: 3387: 3383: 3378: 3373: 3368: 3363: 3359: 3355: 3351: 3344: 3342: 3333: 3329: 3325: 3321: 3317: 3313: 3305: 3297: 3293: 3288: 3283: 3279: 3275: 3271: 3267: 3263: 3256: 3248: 3244: 3240: 3236: 3232: 3228: 3220: 3213: 3201: 3197: 3193: 3187: 3179: 3175: 3170: 3165: 3161: 3157: 3153: 3149: 3145: 3138: 3136: 3127: 3123: 3118: 3113: 3109: 3105: 3101: 3097: 3093: 3086: 3078: 3074: 3069: 3064: 3060: 3056: 3052: 3048: 3044: 3037: 3029: 3025: 3021: 3017: 3013: 3009: 3001: 2985: 2981: 2977: 2971: 2969: 2967: 2965: 2963: 2961: 2959: 2957: 2948: 2944: 2940: 2936: 2932: 2928: 2921: 2919: 2917: 2908: 2904: 2900: 2896: 2892: 2888: 2884: 2880: 2873: 2871: 2869: 2867: 2865: 2863: 2861: 2859: 2857: 2855: 2853: 2851: 2849: 2847: 2845: 2843: 2841: 2839: 2837: 2835: 2818: 2814: 2810: 2804: 2802: 2800: 2798: 2796: 2794: 2777: 2773: 2769: 2763: 2761: 2759: 2757: 2755: 2753: 2751: 2749: 2747: 2745: 2743: 2741: 2724: 2720: 2716: 2710: 2708: 2706: 2704: 2702: 2700: 2680: 2676: 2669: 2663: 2647: 2643: 2639: 2633: 2631: 2629: 2627: 2625: 2623: 2606: 2602: 2598: 2592: 2576: 2572: 2568: 2564: 2558: 2543: 2539: 2535: 2529: 2513: 2509: 2505: 2499: 2495: 2487: 2485: 2481: 2476: 2474: 2464: 2462: 2451: 2449: 2445: 2435: 2432: 2429: 2425: 2421: 2417: 2416:hydrochloride 2407: 2396: 2391: 2375: 2370: 2363: 2358: 2357: 2356: 2354: 2344: 2341: 2339: 2325: 2321: 2319: 2315: 2309: 2307: 2303: 2299: 2295: 2292:Atomoxetine, 2290: 2288: 2280: 2273: 2269: 2265: 2261: 2255: 2253: 2245: 2241: 2236: 2234: 2226: 2222: 2212: 2210: 2206: 2202: 2197: 2195: 2188: 2181: 2174: 2167: 2160: 2152: 2150: 2145: 2140: 2138: 2134: 2130: 2126: 2118: 2114: 2106: 2098: 2093: 2091: 2087: 2082: 2078: 2077:microdialysis 2074: 2070: 2066: 2061: 2059: 2055: 2051: 2047: 2043: 2039: 2038:catecholamine 2036: 2032: 2028: 2018: 2009: 2005: 2002: 1999: 1997: 1994: 1993: 1987: 1982: 1979: 1977: 1970: 1969: 1963: 1958: 1955: 1953: 1946: 1945: 1939: 1934: 1931: 1929: 1922: 1921: 1917: 1914: 1911: 1909: 1903: 1902: 1898: 1895: 1892: 1890: 1884: 1883: 1879: 1876: 1873: 1871: 1865: 1864: 1860: 1857: 1854: 1852: 1846: 1845: 1841: 1838: 1835: 1833: 1827: 1826: 1822: 1819: 1816: 1814: 1808: 1807: 1803: 1800: 1797: 1795: 1789: 1788: 1784: 1781: 1778: 1776: 1770: 1769: 1763: 1758: 1755: 1753: 1747: 1746: 1740: 1735: 1732: 1730: 1724: 1723: 1719: 1716: 1713: 1711: 1705: 1704: 1698: 1693: 1690: 1688: 1682: 1681: 1675: 1670: 1667: 1665: 1659: 1658: 1652: 1647: 1644: 1642: 1636: 1635: 1632: 1631: 1625: 1620: 1618: 1615: 1613: 1612: 1608: 1607: 1603: 1600: 1598: 1595: 1593: 1592: 1585: 1584: 1578: 1573: 1570: 1568: 1562: 1561: 1555: 1552: 1549: 1546: 1544: 1540: 1534: 1533: 1527: 1525:(antagonist?) 1524: 1521: 1516: 1511: 1506: 1505: 1499: 1497:(antagonist?) 1496: 1493: 1490: 1488: 1484: 1478: 1477: 1471: 1466: 1463: 1461: 1458: 1457: 1454: 1451: 1449: 1446: 1444: 1441: 1439: 1435: 1429: 1428: 1422: 1420: 1417: 1415: 1412: 1410: 1406: 1400: 1399: 1393: 1388: 1383: 1380: 1379: 1361: 1357: 1353: 1349: 1345: 1341: 1337: 1333: 1331: 1323: 1319: 1315: 1311: 1303: 1302:phenylephrine 1299: 1297: 1293: 1289: 1285: 1281: 1278: 1275: 1274: 1273: 1270: 1268: 1264: 1260: 1256: 1249: 1244: 1242: 1238: 1234: 1230: 1226: 1222: 1212: 1204: 1201: 1197: 1192: 1190: 1189:breastfeeding 1186: 1182: 1178: 1174: 1170: 1166: 1162: 1150: 1147:Narrow angle 1146: 1144: 1140: 1138: 1135: 1132: 1129: 1125: 1121: 1119: 1116: 1114: 1111: 1109: 1106: 1104: 1101: 1099: 1096: 1094: 1090: 1089: 1087: 1086: 1085: 1077: 1075: 1071: 1067: 1063: 1059: 1055: 1051: 1047: 1043: 1039: 1035: 1031: 1021: 1019: 1015: 1011: 1007: 992: 988: 986: 982: 978: 969: 965: 963: 957: 955: 951: 947: 946:Meta-analyses 943: 933: 931: 921: 914: 912: 911:breastfeeding 908: 904: 900: 896: 892: 887: 885: 880: 876: 872: 868: 864: 861: 857: 853: 843: 836: 830: 821: 816: 815: 812: 805: 796: 795: 792: 785: 778: 774: 773: 771: 768: 763: 756: 754: 750: 729: 727: 723: 718: 714: 710: 707: 705: 703:ECHA InfoCard 699: 691: 687: 686:DTXSID9044297 683: 682: 680: 671: 667: 660: 656:as HCl:  655: 652: 648: 647: 645: 643: 639: 632: 628:as HCl:  627: 624: 620: 619: 617: 615: 611: 604: 600:as HCl:  599: 596: 592: 591: 589: 587: 583: 576: 572:as HCl:  571: 568: 564: 563: 561: 559: 555: 548: 544:as HCl: 543: 540: 536: 535: 533: 531: 527: 520: 516:as HCl:  515: 512: 508: 507: 505: 503: 499: 492: 488: 487: 485: 483: 479: 472: 468:as HCl: 467: 464: 460: 459: 457: 450: 446: 439: 435:as HCl:  434: 431: 427: 426: 424: 422: 418: 410: 406: 401: 400: 397: 390: 385: 381: 378: 376: 372: 368: 366: 359: 356: 352: 349: 347: 343: 339: 337: 333: 329: 327: 323: 319: 315: 309: Rx-only 302: 299: 287: 284: 274: 272: 263: 260: 250: 247: 237: 236: 234: 232: 228: 223: 215: 210: 207: 206: 204: 202: 198: 195: 192: 190: 186: 182: 179: 177: 171: 165: 156: 155: 153: 151: 145: 138: 133: 124: 123: 121: 119: 115: 111: 107: 105: 101: 97: 93: 91: 87: 83: 79: 75: 71: 67: 63: 60: 56: 54: 50: 47:Clinical data 45: 41: 36: 32: 27: 19: 19614: 19593:Prodynorphin 19585:Propeptides: 19584: 19483: 19454:Thienorphine 19277:JNJ-19385899 19262:Cebranopadol 19244:Ac-RYYRIK-NH 19236:Ac-RYYRWK-NH 18920:6β-Naltrexol 18837:Thienorphine 18802:Salvinorin A 18602:Levallorphan 18407:Cebranopadol 18266:Thienorphine 18076:6β-Naltrexol 17860:JNJ-20788560 17855:Isomethadone 17750:Deltorphin I 17745:Deltorphin A 17725:Cebranopadol 17720:Casokefamide 17554:Naltrexazone 17544:Naloxonazine 17469:Levallorphan 17316:6β-Naltrexol 17215:Thienorphine 17170:Remifentanil 17092: 17023:Nicomorphine 17018:Nicodicodine 16973:Morphiceptin 16873:Ketobemidone 16708:Desomorphine 16693:DAMGO (DAGO) 16673:Cebranopadol 16668:Casokefamide 16408: 16407: 16392: 16380: 16377: 16367: 16277:Bietaserpine 16249:Amphetamines 16172:Mifepristone 16162:Medifoxamine 16044: 15987:Clomipramine 15982:Cianopramine 15973: 15826:Diclofensine 15796:Brasofensine 15772: 15699: 15696: 15684:Vortioxetine 15635: 15554:Escitalopram 15510: 15432:Indeloxazine 15424: 15361: 15344:Oxaprotiline 15325: 15313:Trimipramine 15268:Clomipramine 15263:Cianopramine 15258:Butriptyline 15249: 15102:Diclofensine 15072:Brasofensine 15048: 14975: 14972: 14960:Solriamfetol 14886: 14869:Teniloxazine 14829:Esreboxetine 14800: 14732:Solriamfetol 14652:Medifoxamine 14542:Dimethocaine 14532:Diclofensine 14504: 14456: 14344:Difluoropine 14339:Dichloropane 14324:Brasofensine 14310: 14298:Pyrovalerone 14274: 14199:Piperidines: 14198: 14148:Piperazines: 14147: 14061: 14060: 13971:Talniflumate 13509: 13498:Tetrodotoxin 13488:Neosaxitoxin 13479: 13424: 13398:Propoxycaine 13333:Dimethocaine 13266: 13262: 13231:Valnoctamide 13161:Fosphenytoin 13122: 13096:Procainamide 13086:Pilsicainide 13041:Disopyramide 13027: 13017: 12865: 12833: 12783: 12697: 12665:Ethosuximide 12650:Cloperastine 12628: 12597:Metahexamide 12592:Glycyclamide 12552:Glibornuride 12517: 12466: 12428: 12407:Thioridazine 12362:Promethazine 12347:Orphenadrine 12337:Ketoconazole 12322:Erythromycin 12211: 11974: 11902:Phensuximide 11882:Ochratoxin A 11822:Ethosuximide 11748: 11670:-selective ( 11662: 11572: 11529: 11516: 11498: 11447:ω-Conotoxins 11440: 11390: 11372:Norverapamil 11337:Dexverapamil 11315: 11289:derivatives: 11285: 11282:Vatanidipine 11277:Trombodipine 11242:Palonidipine 11227:Nitrendipine 11182:Mepirodipine 11087:Azelnidipine 11070: 11064: 10967: 10966: 10924:Antagonists: 10923: 10913: 10893: 10864: 10823:Antagonists: 10822: 10794: 10741:Antagonists: 10740: 10722: 10669:Antagonists: 10668: 10653: 10618: 10571: 10530:Antagonists: 10529: 10523:Talaglumetad 10469: 10435: 10389:Antagonists: 10388: 10378: 10375:Talaglumetad 10311: 10248:Dipraglurant 10243:Basimglurant 10234: 10188:Antagonists: 10187: 10177: 10125: 10067:Antagonists: 10066: 10011: 9931: 9924: 9915: 9914: 9898: 9895: 9767: 9674:Cyclopropane 9655: 9638: 9616: 9552: 9504:Propoxyphene 9474:Orphenadrine 9379:Ketobemidone 9344:Eticyclidine 9279:Coronaridine 9264:ARL-15896-AR 9180: 9148: 9060:-Cycloserine 9042:Carisoprodol 8998: 8886: 8884:Antagonists: 8883: 8816: 8811: 8794: 8722:-Cycloserine 8663: 8602: 8599: 8543:Barbiturates 8539: 8516:Selurampanel 8471:Dasolampanel 8458:Antagonists: 8457: 8427: 8360: 8357: 8331: 8268:Cyclopropane 8254:Barbiturates 8250: 8222:Selurampanel 8172:Dasolampanel 8144:Antagonists: 8143: 8127:Pramiracetam 8003: 7951: 7948: 7795:Oxitriptan ( 7787: 7671:aripiprazole 7629: 7578:Metralindole 7569: 7539: 7529: 7508:Pivhydrazine 7498:Pheniprazine 7444: 7350:Trimipramine 7340:Quinupramine 7240:Clomipramine 7235:Butriptyline 7158:Teniloxazine 7153:Tandospirone 7138:Metryptamine 7133:Medifoxamine 7118:Indeloxazine 7072:Vortioxetine 6934: 6834:Escitalopram 6504: 6365:. Retrieved 6343: 6310: 6306: 6300: 6267: 6263: 6257: 6249: 6234: 6227: 6194: 6190: 6184: 6165: 6159: 6122: 6118: 6108: 6096:. Retrieved 6083: 6060:the original 6047: 6039:the original 6034: 6025: 6013:. Retrieved 6008: 5999: 5987:. Retrieved 5974: 5965: 5940: 5932: 5913: 5894: 5867: 5861: 5828: 5824: 5818: 5785: 5781: 5759:. Retrieved 5747: 5735: 5700: 5696: 5656: 5652: 5646: 5611: 5607: 5597: 5560: 5556: 5546: 5513: 5509: 5502: 5469: 5465: 5421: 5417: 5387: 5383: 5377: 5368: 5340: 5336: 5329: 5302: 5298: 5260: 5256: 5250: 5223: 5219: 5179: 5175: 5126: 5122: 5112: 5100:. Retrieved 5091: 5074: 5062:. Retrieved 5046: 4994: 4990: 4980: 4945: 4941: 4931: 4894: 4890: 4848: 4844: 4834: 4804:(1): 30–35. 4801: 4797: 4790: 4778:. Retrieved 4774:the original 4769: 4765: 4756: 4744:. Retrieved 4719: 4710: 4675: 4671: 4661: 4636: 4632: 4625: 4590: 4580: 4572: 4552: 4548: 4542: 4497: 4493: 4458:(1): 85–88. 4455: 4451: 4430:. Retrieved 4418: 4405: 4393:. Retrieved 4360: 4356: 4346: 4311: 4307: 4297: 4264: 4260: 4253: 4218: 4214: 4204: 4182:(1): 38–42. 4179: 4175: 4168: 4133: 4129: 4119: 4084: 4080: 4070: 4037: 4033: 4027: 4008: 4002: 3965: 3961: 3913: 3909: 3871: 3867: 3860: 3835: 3831: 3824: 3812:. Retrieved 3803: 3794: 3782:. Retrieved 3773: 3764: 3739: 3735: 3728: 3716:. Retrieved 3707: 3698: 3686:. Retrieved 3677: 3668: 3635: 3631: 3610:. Retrieved 3601: 3570: 3550:. Retrieved 3517: 3513: 3488:. Retrieved 3455: 3451: 3411: 3407: 3357: 3353: 3315: 3311: 3304: 3269: 3265: 3255: 3230: 3226: 3219: 3211: 3204:. Retrieved 3195: 3186: 3151: 3147: 3099: 3095: 3085: 3050: 3046: 3036: 3014:(1): 38–42. 3011: 3007: 3000: 2988:. Retrieved 2979: 2930: 2926: 2882: 2878: 2821:. Retrieved 2812: 2780:. Retrieved 2771: 2727:. Retrieved 2718: 2686:. Retrieved 2674: 2662: 2650:. Retrieved 2642:DailyMed.gov 2641: 2609:. Retrieved 2600: 2591: 2579:. Retrieved 2557: 2545:. Retrieved 2537: 2528: 2516:. Retrieved 2507: 2498: 2477: 2470: 2457: 2441: 2433: 2413: 2404: 2352: 2350: 2342: 2335: 2313: 2310: 2305: 2293: 2291: 2268:Steady-state 2263: 2259: 2256: 2251: 2237: 2218: 2198: 2159:ion channels 2148: 2146:currents in 2141: 2094: 2062: 2024: 2016: 2011:Values are K 1918:>100,000 1861:>100,000 1842:>100,000 1617:0.66 - 3,470 1616: 1609: 1596: 1586: 1550: 1535: 1522: 1494: 1479: 1452: 1447: 1442: 1430: 1418: 1413: 1401: 1366:Pharmacology 1335: 1322:isoprenaline 1312:, including 1271: 1245: 1240: 1218: 1215:Interactions 1210: 1193: 1181:hypertension 1158: 1093:hypertension 1083: 1034:frontal lobe 1027: 1003: 989: 970: 966: 958: 939: 927: 924:Medical uses 915: 888: 855: 851: 850: 839:   833:   631:CHEBI:331697 623:CHEBI:127342 519:DBSALT001207 408: 404: 369:4.5–25 hours 362:Elimination 231:Legal status 225:Legal status 118:License data 77: 73: 69: 18: 19523:Kelatorphan 19500:Candoxatril 19389:Antagonists 19340:Racemorphan 19307:NNC 63-0532 19292:Lexanopadol 19287:Levorphanol 19165:Quadazocine 19150:Pawhuskin A 19145:Noribogaine 19135:Navacaprant 19125:Naltrindole 19045:Epicatechin 19010:Clocinnamox 18893:Antagonists 18855:desipramine 18822:Samidorphan 18792:Racemorphan 18777:Phenazocine 18767:Pentazocine 18747:Norketamine 18742:Noribogaine 18702:Nalfurafine 18667:Mirtazapine 18657:Metkefamide 18617:Lexanopadol 18612:Levorphanol 18592:Laudanosine 18577:ICI-204,448 18572:ICI-199,441 18542:Hemorphin-4 18502:Erinacine E 18487:Eluxadoline 18477:Dynorphin A 18422:Cyclazocine 18397:Butorphanol 18382:Bremazocine 18357:Asimadoline 18347:Allomatrine 18337:Akuammicine 18246:Quadazocine 18241:Pawhuskin A 18236:Noribogaine 18221:Naltrindole 18161:Epicatechin 18156:Eluxadoline 18131:Clocinnamox 18059:Antagonists 17990:Samidorphan 17980:Racemorphan 17960:Oxymorphone 17920:Mitragynine 17915:Metkefamide 17895:Lexanopadol 17890:Levorphanol 17875:Laudanosine 17840:Hydrocodone 17835:Hemorphin-4 17735:Cyclazocine 17710:Butorphanol 17685:β-Endorphin 17604:Samidorphan 17599:Quadazocine 17589:Pawhuskin A 17579:Noribogaine 17569:Naltrindole 17504:Naldemedine 17434:Epicatechin 17391:Clocinnamox 17279:Antagonists 17250:Tubotaiwine 17235:Trimebutine 17165:Racemorphan 17135:Piritramide 17120:Phenazocine 17105:Pentazocine 17078:Oxymorphone 17043:Oliceridine 17028:Norketamine 17013:Nicocodeine 16998:Naltalimide 16963:Mitragynine 16953:Metkefamide 16923:Loxicodegol 16913:Lexanopadol 16908:Levorphanol 16883:Laudanosine 16848:Hydrocodone 16843:Hodgkinsine 16833:Hemorphin-4 16823:Frakefamide 16783:Embutramide 16778:Dynorphin A 16738:Eluxadoline 16728:Dimenoxadol 16663:Carfentanil 16648:Butorphanol 16623:Bezitramide 16593:β-Endorphin 16583:Anileridine 16573:Akuammidine 16568:Akuammicine 16538:α-Narcotine 16420:Adrenergics 16347:Valbenazine 16337:Rose bengal 16282:Deserpidine 16253:amphetamine 16203:levorphanol 16147:Dextrorphan 16100:ziprasidone 16082:pheniramine 16017:Lofepramine 15997:Desipramine 15946:Tesofensine 15936:Sibutramine 15911:Perafensine 15871:JNJ-7925476 15866:Indatraline 15811:Dasotraline 15781:Amifitadine 15760:Venlafaxine 15740:Milnacipran 15639:Etoperidone 15619:Seproxetine 15609:Pirandamine 15589:Omiloxetine 15569:Fluvoxamine 15529:Cericlamine 15519:Alaproclate 15466:levorphanol 15395:ziprasidone 15377:pheniramine 15349:Setiptiline 15334:Maprotiline 15293:Lofepramine 15273:Desipramine 15222:Tesofensine 15212:Sibutramine 15187:Perafensine 15147:JNJ-7925476 15142:Indatraline 15087:Dasotraline 15057:Amifitadine 15036:Venlafaxine 15011:Milnacipran 14940:Nomifensine 14905:Fencamfamin 14834:Lortalamine 14824:Edivoxetine 14814:Ciclazindol 14809:Alseroxylon 14757:Venlafaxine 14737:Tametraline 14727:Sibutramine 14702:Perafensine 14682:Nomifensine 14612:Indatraline 14587:Fencamfamin 14562:DOV-216,303 14557:DOV-102,677 14517:Dasotraline 14512:Ciclazindol 14470:Armodafinil 14465:Amifitadine 14414:Tesofensine 14222:Difemetorex 13637:Triamterene 13591:Poneratoxin 13581:Ciguatoxins 13468:Raxatrigine 13463:Ralfinamide 13458:PF-05089771 13453:PF-04531083 13425:Analgesics: 13383:Piperocaine 13368:Meprylcaine 13363:Mepivacaine 13318:Cinchocaine 13297:Ropivacaine 13289:Bupivacaine 13216:Sipatrigine 13201:Pheneturide 13196:Phenacemide 13181:Mephenytoin 13166:Lamotrigine 13146:Elpetrigine 13101:Propafenone 13046:Dronedarone 12622:Tolbutamide 12612:Repaglinide 12607:Nateglinide 12602:Mitiglinide 12582:Glisoxepide 12567:Glimepiride 12557:Glicaramide 12537:Carbutamide 12439:Linopirdine 12422:Vernakalant 12412:Tolterodine 12402:Terfenadine 12392:Tamulotoxin 12387:Solifenacin 12357:PNU-282,987 12332:Haloperidol 12327:Gigactonine 12307:Domperidone 12292:Darifenacin 12257:Bedaquiline 12242:Azaspiracid 12205:Vernakalant 12140:Linopirdine 12100:Dronedarone 12090:Dendrotoxin 12075:Clamikalant 11947:Tolperisone 11942:Tetrandrine 11932:Sipatrigine 11927:Silperisone 11912:Prenylamine 11852:Lidoflazine 11807:Elpetrigine 11717:Mirogabalin 11621:Lamotrigine 11616:Flunarizine 11611:Efonidipine 11601:Cinnarizine 11596:Cilnidipine 11551:NNC 55-0396 11477:Ralfinamide 11424:Fantofarone 11419:Dronedarone 11404:Budiodarone 11399:Brinazarone 11362:Levemopamil 11262:Sornidipine 11257:Sagandipine 11247:Pranidipine 11222:Nisoldipine 11212:Nilvadipine 11202:Niguldipine 11192:Nicardipine 11157:Lemildipine 11142:Iganidipine 11137:Furnidipine 11102:Cronidipine 11097:Clevidipine 11092:Barnidipine 11082:Aranidipine 10650:VU-0155,041 10575:Decoglurant 10439:Decoglurant 10273:Raseglurant 10221:Remeglurant 10206:Mavoglurant 10070:BAY 36-7620 9864:Pentamidine 9849:Minocycline 9829:Hodgkinsine 9799:Dexanabinol 9729:Sevoflurane 9583:Isoxsuprine 9578:Haloperidol 9558:Besonprodil 9519:Rimantadine 9469:Norketamine 9464:Noribogaine 9439:Milnacipran 9404:Levorphanol 9354:Gacyclidine 9324:Dizocilpine 9319:Diphenidine 9309:Dextrorphan 9229:Alaproclate 9172:Huperzine A 9125:Meprobamate 9085:Harkoseride 8980:Perzinfotel 8857:Plazinemdor 8404:Kainic acid 8389:Domoic acid 8335:Minocycline 8323:Sevoflurane 8000:Willardiine 7975:Domoic acid 7834:from market 7777:brexanolone 7691:risperidone 7588:Moclobemide 7570:Reversible: 7530:Reversible: 7453:Iproclozide 7388:Setiptiline 7383:Mirtazapine 7373:Maprotiline 7330:Propizepine 7315:Noxiptiline 7300:Metapramine 7290:Lofepramine 7260:Dimetacrine 7250:Desipramine 7123:Flupentixol 7108:Etryptamine 7093:Amisulpride 7088:Agomelatine 7034:Etoperidone 7011:Setiptiline 7006:Mirtazapine 6978:Nomifensine 6935:Atomoxetine 6912:Venlafaxine 6902:Milnacipran 6844:Fluvoxamine 6614:Venlafaxine 6599:Moclobemide 6594:Milnacipran 6579:Desipramine 6505:Atomoxetine 6500:Armodafinil 6435:Amphetamine 5761:30 November 5614:(3): e373. 5343:: 164–171. 4780:10 November 4517:2066/225901 4500:: 270–278. 4432:28 February 4395:28 February 3742:: 149–159. 3272:: 789–818. 2823:10 November 2782:10 November 2729:10 November 2652:26 February 2454:Brand names 2088:effects of 2069:PET imaging 1915:>100,000 1899:>10,000 1880:>10,000 1858:>100,000 1855:>100,000 1839:>100,000 1836:>100,000 1804:>10,000 1604:>10,000 1344:desipramine 1074:case report 882:medication 852:Atomoxetine 760: g·mol 709:100.120.306 387:Identifiers 137:Atomoxetine 104:MedlinePlus 65:Other names 57:Strattera, 53:Trade names 23:Atomoxetine 19698:Nootropics 19662:Categories 19618:Kyotorphin 19563:Spinorphin 19444:SB-612,111 19439:Nocistatin 19409:BAN-ORL-24 19360:SCH-486757 19355:SCH-221510 19194:Nociceptin 19155:PF-4455242 19130:Naringenin 19120:Naltrexone 19080:LY-2795050 19075:LY-2459989 19070:LY-2444296 19065:LY-2196044 19050:Hyperoside 18965:Aticaprant 18859:imipramine 18782:Proxorphan 18757:Oxilorphan 18727:Niravoline 18717:Nalorphine 18692:Nalbuphine 18677:Moxazocine 18652:Metazocine 18622:Lofentanil 18587:Ketazocine 18547:Herkinorin 18527:Gemazocine 18517:Fedotozine 18497:Eptazocine 18427:Cyclorphan 18412:Ciprefadol 18231:Naringenin 18211:Naltrexone 18206:Nalorphine 18181:LY-2196044 18171:ICI-174864 18166:ICI-154129 18111:Bevenopran 18086:α-Santolol 18050:Zenazocine 18030:Tonazocine 17985:RWJ-394674 17970:Proglumide 17910:Metazocine 17900:Lofentanil 17830:Fluorophen 17594:Rimonabant 17584:Oxilorphan 17574:Naringenin 17564:Naltrexone 17529:Naloxazone 17519:Nalorphine 17484:LY-2196044 17454:Hyperoside 17444:Gemazocine 17439:Eptazocine 17376:Bevenopran 17220:Tianeptine 17195:Tapentadol 17190:Sufentanil 17185:Sinomenine 17175:Salsolinol 17130:Piminodine 17048:Oxycodegol 17038:Octreotide 17033:Nufenoxole 16983:Nalbuphine 16938:Meptazinol 16918:Loperamide 16888:Lefetamine 16838:Herkinorin 16818:Fluorophen 16773:Dipipanone 16698:Dermorphin 16588:Apparicine 16578:Alfentanil 16501:(abridged; 16481:modulators 16396:SoRI-20041 16389:SoRI-20040 16317:Ketanserin 16244:Amiodarone 16207:tapentadol 16167:Mesembrine 16137:Delucemine 16114:esketamine 16027:Pipofezine 16012:Imipramine 15931:SEP-228432 15926:SEP-228431 15896:Nefazodone 15881:Liafensine 15851:Fezolamine 15841:DOV-216303 15836:DOV-102677 15791:Bicifadine 15786:Ansofaxine 15725:Eclanamine 15720:Duloxetine 15705:Bicifadine 15679:Vilazodone 15649:Lubazodone 15644:Litoxetine 15629:Zimelidine 15624:Sertraline 15599:Paroxetine 15594:Panuramine 15564:Fluoxetine 15559:Femoxetine 15539:Dapoxetine 15534:Citalopram 15458:tapentadol 15437:Nefazodone 15420:Ephenidine 15415:Dopexamine 15298:Melitracen 15288:Imipramine 15207:SEP-228432 15202:SEP-228431 15172:Nefazodone 15157:Liafensine 15127:Fezolamine 15117:DOV-216303 15112:DOV-102677 15067:Bicifadine 15062:Ansofaxine 15021:Nafenodone 14996:Eclanamine 14991:Duloxetine 14950:Radafaxine 14930:Manifaxine 14915:Lefetamine 14890:Amineptine 14874:Viloxazine 14849:Reboxetine 14844:Nisoxetine 14722:Sertraline 14712:Radafaxine 14697:Oroxylin A 14642:Manifaxine 14632:Liafensine 14622:Lefetamine 14602:GYKI-52895 14592:Fezolamine 14577:Esketamine 14572:Ephenidine 14495:BTS 74,398 14485:Ansofaxine 14480:Amineptine 14359:FP-β-CPPIT 14354:FE-β-CPPIT 14293:Prolintane 14186:Vanoxerine 14181:Nefazodone 13941:Bumetanide 13879:Activators 13869:Piretanide 13864:Lonidamine 13815:Activators 13800:Mibefradil 13795:Mefloquine 13785:Furosemide 13780:Fluoxetine 13760:Crofelemer 13647:Activators 13570:Versutoxin 13566:Robustoxin 13548:Activators 13533:Safinamide 13483:Conotoxins 13418:Trimecaine 13413:Tetracaine 13388:Prilocaine 13378:Orthocaine 13353:Iontocaine 13348:Hexylcaine 13343:Etidocaine 13284:Benzocaine 13274:Amylocaine 13256:Zonisamide 13251:Valpromide 13221:Topiramate 13211:Rufinamide 13171:Lacosamide 13136:Cenobamate 13091:Prajmaline 13081:Moricizine 13076:Mexiletine 13071:Lorcainide 13056:Flecainide 13021:Ranolazine 12961:Activators 12946:Fluoxetine 12890:Nimesulide 12872:-specific: 12858:Activators 12840:-specific: 12792:-specific: 12772:Rilmakalim 12762:Nicorandil 12722:Cromakalim 12709:-specific: 12690:Activators 12680:Tipepidine 12670:Ifenprodil 12645:Caramiphen 12637:-specific: 12617:Tolazamide 12577:Gliquidone 12562:Gliclazide 12529:-specific: 12482:Retigabine 12477:Flupirtine 12474:-specific: 12459:Activators 12436:-specific: 12417:Vanoxerine 12397:Terodiline 12382:Sertindole 12372:Ranolazine 12237:Astemizole 12227:Amiodarone 12195:Terikalant 12170:Pinokalant 12155:Nifekalant 12150:Maurotoxin 12145:Lolitrem B 12135:Kaliotoxin 12095:Dofetilide 12085:Dalazatide 12080:Conotoxins 12050:Amiodarone 12045:Almokalant 11967:Activators 11957:Valperinol 11937:Terodiline 11877:Naftopidil 11867:Mesuximide 11797:Enpiperate 11777:Cycleanine 11762:Bevantolol 11752:Bencyclane 11742:Pregabalin 11732:PD-299,685 11727:PD-217,014 11722:PD-200,347 11712:Imagabalin 11702:Gabapentin 11692:Atagabalin 11682:Arbaclofen 11641:Mibefradil 11636:Loperamide 11631:Lomerizine 11606:Dotarizine 11586:Benidipine 11566:Zonisamide 11482:Safinamide 11457:Caroverine 11409:Celivarone 11357:Gallopamil 11312:Siratiazem 11302:Iprotiazem 11292:Clentiazem 11272:Tiamdipine 11267:Teludipine 11232:Olradipine 11217:Nimodipine 11207:Niludipine 11197:Nifedipine 11187:Mesudipine 11177:Manidipine 11152:Lacidipine 11147:Isradipine 11132:Flordipine 11127:Felodipine 11122:Elnadipine 11117:Elgodipine 11107:Darodipine 11077:Amlodipine 10917:AZ12216052 10657:Foliglurax 10645:VU-001,171 10558:LY-341,495 10553:LY-307,452 10508:LY-487,379 10498:LY-379,268 10417:LY-341,495 10412:LY-307,452 10360:LY-566,332 10355:LY-487,379 10345:LY-379,268 10201:LY-344,545 10181:LSN2463359 10090:LY-456,236 10085:LY-367,385 9979:modulators 9902:AGN-241751 9874:Piretanide 9824:Furosemide 9809:Flupirtine 9786:Conantokin 9781:Caroverine 9776:Bumetanide 9709:Isoflurane 9679:Desflurane 9669:Chloroform 9608:Safaprodil 9603:Ro 25-6981 9544:Tiletamine 9529:Sabeluzole 9509:Remacemide 9454:Neramexane 9424:Methorphan 9409:Loperamide 9384:Lanicemine 9369:Indantadol 9334:Esketamine 9329:Ephenidine 9289:Dexoxadrol 9254:Arketamine 9239:Amantadine 9199:3-MeO-PCMo 9177:Putrescine 9120:MDL-105519 9095:Kynurenine 9075:Gavestinel 8990:SDZ-220581 8950:MDL-100453 8833:prasterone 8803:Spermidine 8776:Milacemide 8681:ACC (ACPC) 8567:Evans blue 8531:Topiramate 8521:Tezampanel 8451:Isoflurane 8328:Talampanel 8313:Perampanel 8308:Isoflurane 8293:GYKI-53655 8288:GYKI-52466 8283:Evans blue 8247:Zonampanel 8237:Topiramate 8227:Tezampanel 8202:Kynurenine 8162:Caroverine 8157:Becampanel 8107:Oxiracetam 8007:Aniracetam 7928:modulators 7885:modulators 7809:Tryptophan 7781:zuranolone 7687:quetiapine 7683:olanzapine 7679:lurasidone 7633:Selegiline 7623:-selective 7603:Toloxatone 7598:Tetrindole 7593:Pirlindole 7573:Eprobemide 7563:-selective 7543:Bifemelane 7533:Caroxazone 7493:Phenelzine 7478:Mebanazine 7458:Iproniazid 7345:Tianeptine 7325:Pipofezine 7295:Melitracen 7275:Imipramine 7255:Dibenzepin 7215:Amineptine 7163:Tianeptine 7148:Pivagabine 7143:Oxaflozane 7103:Esketamine 7067:Vilazodone 7039:Nefazodone 6968:Amineptine 6945:Viloxazine 6940:Reboxetine 6892:Duloxetine 6864:Zimelidine 6859:Sertraline 6854:Paroxetine 6839:Fluoxetine 6829:Citalopram 6630:Amantadine 6609:Reboxetine 6589:Imipramine 6584:Duloxetine 6546:Guanfacine 6515:Viloxazine 6492:stimulants 6427:stimulants 6367:7 February 5337:NeuroImage 4897:: 952584. 4555:: 445–80. 4357:Pediatrics 3718:14 January 3688:14 January 3634:(Review). 3552:7 December 3490:7 December 3233:: 105703. 2581:19 October 2547:22 October 2518:7 February 2490:References 2318:conjugates 2238:Following 1896:>10,000 1893:>10,000 1877:>10,000 1874:>10,000 1801:>30,000 1601:>30,000 1547:>1,000? 1352:paroxetine 1318:dobutamine 1286:, such as 1259:arrhythmia 1237:paroxetine 1233:fluoxetine 1161:angioedema 1068:following 1054:depression 995:Other uses 981:guanfacine 891:angioedema 863:medication 765:3D model ( 753:Molar mass 659:ChEMBL1702 575:57WVB6I2W0 567:ASW034S0B8 530:ChemSpider 482:IUPHAR/BPS 438:82248-59-7 430:83015-26-3 421:CAS Number 396:IUPAC name 346:Metabolism 189:Drug class 19573:Tynorphin 19568:Thiorphan 19548:Opiorphan 19490:Amastatin 19419:J-113,397 19380:TH-030418 19350:Ro65-6570 19345:Ro64-6198 19272:Etorphine 19180:Zyklophin 19170:Taxifolin 19060:LY-255582 19020:Cyclofoxy 18970:Axelopran 18884:Xorphanol 18874:U-54,494A 18842:Tifluadom 18832:TH-030418 18762:Oxycodone 18752:Oripavine 18722:Naltriben 18707:Nalmefene 18662:Mianserin 18632:Lufuradom 18537:GR-103545 18512:Etorphine 18492:Enadoline 18392:Butorphan 18387:BRL-52537 18352:Apadoline 18261:Taxifolin 18256:SoRI-9409 18216:Naltriben 18201:Nalmefene 18176:LY-255582 18106:Axelopran 18045:Xorphanol 18015:TH-030418 17995:SB-235863 17955:Oxycodone 17950:Oripavine 17815:Etorphine 17705:Butorphan 17670:Amoxapine 17609:Taxifolin 17534:Naloxegol 17509:Nalmefene 17479:LY-255582 17409:Cyprodime 17404:Cyclofoxy 17371:Axelopran 17351:Alvimopan 17346:Akuammine 17331:α-Gliadin 17270:Xorphanol 17260:Valorphin 17205:TH-030418 17063:Oxycodone 17058:Oripavine 16993:Nalmexone 16948:Methadone 16928:LS-115509 16808:Etorphine 16798:Eseroline 16643:Butorphan 16504:full list 16409:See also: 16384:SoRI-9804 16332:Reserpine 16302:GBR-12935 16297:Efavirenz 16217:Roxindole 16195:methadone 16182:N-Me-5-HT 16152:Efavirenz 16110:3-MeO-PCP 16053:Amoxapine 15921:Pridefine 15891:Naphyrone 15755:Tofenacin 15674:Trazodone 15664:SB-649915 15659:Quipazine 15654:LY-393558 15579:Ifoxetine 15574:Indalpine 15450:methadone 15339:Mianserin 15329:Amoxapine 15197:Pridefine 15167:Naphyrone 15031:Tofenacin 14981:CP-39,332 14900:Fencamine 14895:Bupropion 14864:Tandamine 14859:Talsupram 14819:Daledalin 14717:Rimcazole 14707:Pridefine 14672:Modafinil 14597:Fluorenol 14567:Efavirenz 14500:Bupropion 14460:Adrafinil 14424:Tropoxane 14314:Altropane 14311:Tropanes: 14288:Naphyrone 14252:Pipradrol 14171:GBR-13098 14166:GBR-13069 14161:GBR-12935 14156:GBR-12783 14062:See also: 13961:Mepacrine 13907:Ivacaftor 13823:Carbachol 13706:Ibuprofen 13696:Amiloride 13655:Solnatide 13627:Amiloride 13556:Aconitine 13518:Evenamide 13493:Saxitoxin 13408:Risocaine 13358:Lidocaine 13303:Butacaine 13279:Articaine 13206:Phenytoin 13116:Tocainide 13111:Sparteine 13106:Quinidine 13066:Lorajmine 13061:Lidocaine 13051:Encainide 13036:Aprindine 12777:Sarakalim 12767:Pinacidil 12757:Naminidil 12747:Minoxidil 12742:Mazokalim 12727:Diazoxide 12717:Bimakalim 12712:Aprikalim 12675:Tertiapin 12655:Clozapine 12572:Glipizide 12367:Quinidine 12317:Ergtoxins 12282:Cisapride 12272:BRL-32872 12252:Azimilide 12215:(KCNH2, K 12190:Tedisamil 12175:Quinidine 12165:Paxilline 12130:Inakalant 12125:Ibutilide 12110:Hanatoxin 12065:Bunaftine 12060:Bretylium 12055:Azimilide 12040:Adekalant 11999:Potassium 11981:Bay K8644 11922:Sesamodil 11872:Monatepil 11862:Manoalide 11857:Magnesium 11842:Imepitoin 11832:Fendiline 11812:Ethadione 11802:Eperisone 11782:Dauricine 11757:Berbamine 11668:δ subunit 11472:PD-173212 11387:Verapamil 11377:Ronipamil 11367:Nexopamil 11352:Falipamil 11347:Etripamil 11332:Devapamil 11327:Dagapamil 11307:Nictiazem 11297:Diltiazem 11287:Diltiazem 11237:Oxodipine 10968:See also: 10902:Glutamate 10894:Agonists: 10816:LSP2-9166 10803:Glutamate 10795:Agonists: 10726:Glutamate 10723:Agonists: 10635:LSP2-9166 10622:Glutamate 10619:Agonists: 10594:Group III 10580:RO4491533 10488:Glutamate 10483:Eglumegad 10470:Agonists: 10444:RO4491533 10335:Glutamate 10330:Eglumegad 10312:Agonists: 10159:Glutamate 10134:ADX-47273 10126:Agonists: 10050:Ro67-7476 10045:Ro67-4853 10040:Ro01-6128 10025:Glutamate 10012:Agonists: 9916:See also: 9896:Unsorted: 9839:MDL-27266 9819:FR-115427 9814:FPL-12495 9771:ARR-15896 9699:Halothane 9689:Enflurane 9647:Magnesium 9598:Ro 8-4304 9573:Eliprodil 9484:PD-137889 9444:Morphanol 9419:Methadone 9414:Memantine 9364:Ibogamine 9339:Etoxadrol 9269:ARL-16247 9259:ARL-12495 9244:Aptiganel 9209:4-MeO-PCP 9204:3-MeO-PCP 9194:3-MeO-PCE 9157:Co 101676 9130:MRZ 2/576 9080:GV-196771 9070:Felbamate 9047:CGP-39653 9027:ACEA-1328 9022:ACEA-1011 8965:NPC-17742 8960:NPC-12626 8945:LY-274614 8940:LY-235959 8935:LY-233053 8920:CGS-19755 8915:CGP-40116 8910:CGP-39653 8905:CGP-39551 8900:CGP-37849 8890:AP5 (APV) 8791:Sarcosine 8667:β-Fluoro- 8616:Glutamate 8611:Aspartate 8600:Agonists: 8557:Enflurane 8501:LY-382884 8461:ACEA-1011 8446:Halothane 8441:Enflurane 8436:Diazoxide 8409:LY-339434 8394:Glutamate 8358:Agonists: 8303:Irampanel 8298:Halothane 8273:Enflurane 8147:ACEA-1011 8122:Piracetam 8102:ORG-26576 8097:Nooglutyl 8087:LY-503430 8082:LY-451646 8077:LY-404187 8072:LY-395153 8067:LY-392098 8052:Diazoxide 7980:Glutamate 7949:Agonists: 7844:Phase III 7832:Withdrawn 7697:Buspirone 7583:Minaprine 7518:Tedizolid 7513:Safrazine 7488:Octamoxin 7483:Nialamide 7473:Linezolid 7468:Isoniazid 7378:Mianserin 7320:Opipramol 7285:Iprindole 7265:Dosulepin 7230:Amoxapine 7186:Tricyclic 7044:Trazodone 7001:Mianserin 6973:Bupropion 6907:Tofenacin 6849:Indalpine 6798:Specific 6708:Serotonin 6574:Buspirone 6569:Bupropion 6541:Clonidine 6510:Modafinil 6098:1 January 5472:: 58–66. 5257:CNS Drugs 5102:14 August 5088:Database" 4736:241309451 4534:211053123 4289:211134241 3968:: 27–39. 3638:(3): 46. 3602:Drugs.com 3206:1 January 2980:Drugs.com 2721:. WebMD. 2508:Drugs.com 2448:tamoxifen 2428:developed 2385:Synthesis 2347:Chemistry 2289:profile. 2081:serotonin 2071:study on 1756:>1,000 1733:>1,000 1691:>1,000 1668:>1,000 1645:>1,000 1571:>1,000 1491:>1,000 1356:phenytoin 1304:or other 1229:bupropion 1221:substrate 1194:The U.S. 1185:pregnancy 1169:psychosis 1122:Advanced 1060:. A 2015 985:clonidine 942:stimulant 930:indicated 907:pregnancy 899:psychosis 856:Strattera 651:ChEMBL641 375:Excretion 364:half-life 330:63 to 94% 174:Routes of 148:Pregnancy 96:Monograph 90:Drugs.com 19652:Medicine 19459:Trap-101 19449:SR-16430 19370:SR-16435 19224:(PheΨ(CH 19204:Agonists 19115:Naloxone 19025:Dezocine 18995:Catechin 18950:Apigenin 18879:U-69,593 18672:Morphine 18642:MB-1C-OH 18582:Ketamine 18567:Ibogaine 18532:GR-89696 18522:Fentanyl 18402:BW373U86 18290:Agonists 18280:κ-opioid 18226:Naloxone 18121:Catechin 18096:Apigenin 18035:Tramadol 18020:Thebaine 17930:Morphine 17850:Ibogaine 17820:Fentanyl 17800:DPI-3290 17770:Dezocine 17715:BW373U86 17695:Biphalin 17660:ADL-5859 17633:Agonists 17623:δ-opioid 17549:Naloxone 17474:Lobeline 17459:Ibogaine 17381:Catechin 17361:Apigenin 17230:Tramadol 17225:Tilidine 17210:Thebaine 17180:SC-17599 17150:Propiram 17110:Pericine 17053:OM-3-MNZ 16978:Morphine 16868:Ketamine 16813:Fentanyl 16723:Dezocine 16658:BW373U86 16628:Biphalin 16513:3-HO-PCP 16499:Agonists 16489:μ-opioid 16371:Luteolin 16322:Lobeline 16312:Ibogaine 16211:tramadol 16157:Hypidone 16118:ketamine 16096:loxapine 15956:Tropanes 15886:Mazindol 15876:JZ-IV-10 15710:CP-39332 15669:TGBA01AD 15462:tramadol 15405:ketamine 15391:loxapine 15232:Tropanes 15162:Mazindol 15152:JZ-IV-10 14854:Talopram 14839:Mazindol 14804:Amedalin 14662:Metaphit 14657:Mesocarb 14647:Mazindol 14617:Ketamine 14419:Troparil 14176:JJC8-088 14047:instead. 14022:instead. 13933:Blockers 13925:Unsorted 13851:Blockers 13752:Blockers 13729:Chloride 13691:A-317567 13683:Blockers 13632:Benzamil 13619:Blockers 13448:NKTR-171 13443:GDC-0276 13438:Funapide 13433:DSP-2230 13428:AZD-3161 13393:Procaine 13308:Butamben 13156:Ethotoin 13031:Ajmaline 13010:Blockers 12969:Riluzole 12928:Blockers 12826:Blockers 12732:Emakalim 12510:Blockers 12352:Pimozide 12222:Ajmaline 12022:Blockers 11837:Fostedil 11767:Canadine 11737:Phenibut 11697:Baclofen 11646:NP078585 11591:Bepridil 11429:SR-33805 11382:Tiapamil 11342:Emopamil 11322:Anipamil 11057:Blockers 10952:UBP-1112 10868:ADX71743 10856:UBP-1112 10769:UBP-1112 10697:UBP-1112 10568:MGS-0039 10513:MGS-0028 10427:MGS-0039 10365:MGS-0028 10287:Group II 10231:SIB-1893 10226:SIB-1757 10216:NPS-2390 10100:NPS-2390 10060:Theanine 9844:Metaphit 9754:Urethane 9642:Hydrogen 9639:Cations: 9549:Tramadol 9374:Ketamine 9359:Ibogaine 9274:Budipine 9189:3-HO-PCP 9115:LU-73068 9105:L-701324 9100:L-689560 9007:5,7-DCKA 8995:Selfotel 8877:SAGE-718 8872:SAGE-301 8867:SAGE-201 8808:Spermine 8798:Neomycin 8763:-Alanine 8755:L-687414 8714:-Alanine 8671:-alanine 8660:Theanine 8526:Theanine 8424:SYM-2081 8232:Theanine 7770:GABAkine 7448:Benmoxin 7404:Tiazesim 7128:Ketamine 7113:Gepirone 6672:Dopamine 6533:agonists 6361:Archived 6357:28520366 6351:(NCBI). 6319:31823620 6284:26579704 6243:Archived 6219:28907560 6211:26364896 6151:19412494 6092:Archived 5989:26 April 5983:Archived 5853:25708096 5845:15910008 5810:13032441 5802:12485958 5752:Archived 5727:20393461 5673:24410567 5638:24643164 5589:24348020 5538:18339166 5530:25572531 5494:27647092 5486:28167075 5448:20423340 5365:16958660 5357:23933039 5321:20403082 5277:22329564 5242:12431845 5196:15225731 5153:23397050 5096:Archived 5064:6 August 5055:Archived 5021:19154426 4972:40283275 4964:12412820 4923:21765848 4867:27518170 4826:37636280 4818:14709944 4746:12 March 4740:Archived 4702:32394557 4653:20661027 4617:26624881 4608:11092927 4569:24295630 4526:32044373 4472:16456396 4423:Archived 4389:Archived 4385:23501657 4338:29489078 4281:32064995 4245:24206099 4196:27845858 4160:36007816 4111:36007816 4062:22649093 4054:26349559 3994:26730199 3932:23438503 3888:22945622 3852:20403082 3808:Archived 3778:Archived 3756:25813457 3712:Archived 3708:ClinCalc 3682:Archived 3678:ClinCalc 3652:29411149 3606:Archived 3546:Archived 3534:27005307 3484:Archived 3480:43503227 3472:20837981 3430:27390695 3386:22074258 3332:24885846 3296:33549739 3247:38718988 3200:Archived 3178:23560600 3126:24206099 3077:36007816 3028:27845858 2990:22 March 2984:Archived 2947:26314574 2907:25708096 2899:15910008 2817:Archived 2813:DailyMed 2776:Archived 2723:Archived 2679:Archived 2646:Archived 2605:Archived 2575:Archived 2512:Archived 2467:Research 2157:3.1/3.2 2090:tyramine 2046:striatum 2042:dopamine 1395:N-DM-ATX 1390:4-OH-ATX 1360:warfarin 1348:diazepam 1336:In vitro 1316:such as 1314:pressors 1207:Overdose 1177:anorexia 1149:glaucoma 979:such as 842:(verify) 502:DrugBank 259:Class C1 201:ATC code 163: B3 150:category 132:DailyMed 19615:Others: 19543:RB-3007 19495:BL-2401 19464:UFP-101 19429:NalBzOH 19424:JTC-801 19365:SR-8993 19302:MT-7716 19252:BU08070 19105:MR-2266 19085:MeJDTic 19015:CVL-354 18985:BU09059 18975:AZ-MTAB 18955:Arodyne 18915:6'-GNTI 18910:5'-GNTI 18869:U-50488 18849:(e.g., 18697:NalBzOH 18682:MR-2034 18647:Menthol 18637:Matrine 18372:BAM-22P 18367:BAM-18P 18362:BAM-12P 18302:6'-GNTI 18071:5'-NTII 18005:SNC-162 17945:NalBzOH 17865:KNT-127 17795:DPI-221 17730:Codeine 17690:BAM-18P 17680:AZD2327 17645:6'-GNTI 17539:Naloxol 17265:Viminol 17255:U-47700 17240:TRIMU 5 17145:Prodine 17088:OxyPNPH 17003:Neopine 16988:NalBzOH 16958:Metopon 16933:Matrine 16683:Codeine 16633:BU08070 16608:BAM-22P 16603:BAM-18P 16598:BAM-12P 16563:AH-7921 16307:GZ-793A 16251:(e.g., 16189:(e.g., 16187:Opioids 16108:(e.g., 16094:(e.g., 16060:(e.g., 16048:A-80426 16045:Others: 16007:Doxepin 15960:cocaine 15958:(e.g., 15906:NS-2359 15901:Nefopam 15856:HDMP-28 15846:EXP-561 15806:Cocaine 15735:McN5652 15614:RTI-353 15444:(e.g., 15442:Opioids 15403:(e.g., 15389:(e.g., 15367:(e.g., 15362:Others: 15283:Doxepin 15236:cocaine 15234:(e.g., 15182:NS-2359 15177:Nefopam 15132:HDMP-28 15122:EXP-561 15082:Cocaine 15006:McN5652 14925:LR-5182 14687:NS-2359 14677:Nefopam 14637:LR-5182 14582:EXP-561 14457:Others: 14409:RTI-336 14404:RTI-229 14399:RTI-177 14394:RTI-150 14389:RTI-126 14384:RTI-121 14379:RTI-113 14374:RTI-112 14334:Cocaine 14232:HDMP-28 14151:DBL-583 13701:Aspirin 13523:Menthol 13510:Others: 13480:Toxins: 13323:Cocaine 12848:GAL-021 12468:KCNQ (K 12430:KCNQ (K 12247:AZD1305 12185:Sotalol 12180:ShK-186 12160:Notoxin 11847:JTV-519 11827:Fasudil 11556:ProTx I 11536:ABT-639 11523:SNX-482 11394:AH-1058 11391:Others: 11034:Calcium 10258:GRN-529 10253:Fenobam 10238:AZD9272 10174:VU-1545 10075:CPCCOEt 9987:Group I 9888:saffron 9734:Toluene 9724:Octanol 9704:Hexanol 9659:Benzene 9635:TCN-213 9630:TCN-201 9625:MPX-007 9620:MPX-004 9214:8A-PDHQ 9152:Arcaine 9145:ZD-9379 8842:sulfate 8771:-Serine 8745:Glycine 8730:-Serine 8645:Proline 8572:NS-3763 8545:(e.g., 8536:UBP-302 8414:Proline 8256:(e.g., 8132:S-18986 8062:IDRA-21 8047:CX-1942 8042:CX-1739 7990:Proline 7702:Lithium 7270:Doxepin 6802:and/or 6740:(SNDRI) 6292:6229741 6142:2671957 6015:23 July 6009:Reuters 5981:(FDA). 5977:. U.S. 5718:3055469 5629:3966039 5580:3857115 5439:2874851 5396:3965689 5144:3579642 5084:"PDSP K 5080:Roth BL 5012:2697834 4914:3135225 4693:7215080 4377:2011430 4329:6558969 4236:3842866 4151:9943858 4102:9943858 3985:4694693 3784:21 July 3660:3663423 3612:3 March 3421:4898838 3414:: 325. 3377:3229459 3360:: 176. 3287:8328933 3169:3696926 3117:3842866 3068:9943858 2688:12 June 2611:11 June 2461:generic 2410:History 2151:oocytes 2149:Xenopus 2086:pressor 2017:Xenopus 1976:3.1/3.4 1928:3.1/3.2 1823:32,100 1785:19,600 1340:aspirin 1173:suicide 1050:fatigue 1046:arousal 971:Unlike 903:suicide 858:, is a 758:255.361 726:Formula 547:ID49515 511:DB00289 449:PubChem 300:Rx-only 297:WARNING 269:: 217:) 211: ( 209:N06BA09 134::  110:a603013 19638:Portal 19553:Selank 19538:RB-120 19533:RB-101 19477:Others 19404:AT-076 19297:MCOPPB 18960:AT-076 18806:salvia 18687:N-MPPP 18627:LPK-26 18251:SDM25N 18101:AT-076 18040:TRV250 18000:SNC-80 17870:Kratom 17650:7-SIOM 17366:AT-076 17356:AM-251 17245:TRV734 17140:PL-017 16878:Kratom 16863:IBNtxA 16361:Others 15916:PRC200 15861:HP-505 15604:PIM-35 15192:PRC200 15137:HP-505 14945:O-2172 14692:O-2172 14369:RTI-55 13998:Others 12987:Sodium 12640:Barium 12444:XE-991 12312:E-4031 12262:BeKm-1 12232:AmmTX3 12115:HgeTx1 12105:E-4031 11887:Osthol 11656:TROX-1 11541:ML-218 10861:XAP044 10798:AMN082 10478:DCG-IV 10473:CBiPES 10432:PCCG-4 10325:DCG-IV 10320:CBiPES 9764:Xylene 9664:Butane 9037:AV-101 8750:HA-966 8037:CX-717 8027:CX-614 8022:CX-546 8017:CX-516 7827:WHO-EM 7540:Mixed: 7397:Others 7081:Others 6989:NaSSAs 6734:(NDRI) 6728:(SNRI) 6722:(SSRI) 6716:(SERT) 6710:(5-HT) 6653:(ADHD) 6355:  6317:  6290:  6282:  6217:  6209:  6172:  6149:  6139:  5953:  5947:118–20 5925:  5906:  5882:  5851:  5843:  5808:  5800:  5725:  5715:  5671:  5636:  5626:  5587:  5577:  5536:  5528:  5492:  5484:  5446:  5436:  5394:  5363:  5355:  5319:  5275:  5240:  5194:  5151:  5141:  5019:  5009:  4970:  4962:  4921:  4911:  4865:  4824:  4816:  4734:  4700:  4690:  4651:  4615:  4605:  4567:  4532:  4524:  4470:  4383:  4375:  4336:  4326:  4287:  4279:  4243:  4233:  4194:  4158:  4148:  4109:  4099:  4060:  4052:  4015:  3992:  3982:  3940:793033 3938:  3930:  3886:  3850:  3814:17 May 3754:  3658:  3650:  3577:  3542:104938 3540:  3532:  3478:  3470:  3428:  3418:  3384:  3374:  3330:  3294:  3284:  3245:  3176:  3166:  3124:  3114:  3075:  3065:  3026:  2945:  2905:  2897:  2563:Anvisa 2484:autism 2424:patent 2302:CYP2C9 2298:CYP1A2 2287:CYP2D6 2283:trough 2278:trough 2221:CYP2D6 2182:, and 2119:or an 2006:5,710 2003:20,000 1956:12,400 1932:10,900 1912:12,100 1820:56,100 1817:18,000 1798:29,800 1782:20,000 1779:11,400 1720:1,700 1225:CYP2D6 1165:stroke 1052:, and 918:  895:stroke 791:SMILES 642:ChEMBL 603:D02574 595:D07473 380:Kidney 355:CYP2D6 353:, via 294: 281: 271:℞-only 257: 244: 130:  59:others 19558:Semax 19197:(NOP) 19175:UPHIT 19160:RB-64 19100:ML350 19095:ML190 19055:JDTic 19030:DIPPA 18797:RB-64 18552:HS665 18417:CR665 18312:18-MC 18307:8-CAC 18283:(KOR) 17805:DSLET 17790:DPDPE 17740:DADLE 17700:BU-48 17626:(DOR) 17464:JDTic 17326:18-MC 17155:PZM21 17099:opium 17008:NFEPP 16688:DADLE 16492:(MOR) 16232:VMATs 14444:WF-33 14439:WF-31 14434:WF-23 14429:WF-11 14032:LGICs 13739:CaCCs 13711:PcTX1 13670:ASICs 12997:VGSCs 12267:BmTx3 12120:HsTx1 12009:VGKCs 11044:VDCCs 10879:mGluR 10836:MMPIP 10780:mGluR 10708:mGluR 10640:PHCCC 10604:mGluR 10548:HYDIA 10538:CECXG 10533:APICA 10455:mGluR 10407:HYDIA 10397:CECXG 10392:APICA 10297:mGluR 10196:DMeOB 10139:CDPPB 10111:mGluR 10055:VU-71 9997:mGluR 9759:Xenon 9219:18-MC 9184:2-MDP 9012:7-CKA 8975:PEAQX 8701:B6B21 8691:AK-51 8625:-HCA) 8588:NMDAR 8511:NS102 8242:YM90K 7937:AMPAR 7797:5-HTP 7361:TeCAs 7022:SARIs 6956:NDRIs 6875:SNRIs 6817:SSRIs 6704:(NRI) 6698:(NET) 6686:(DRI) 6680:(DAT) 6288:S2CID 6246:(PDF) 6239:(PDF) 6215:S2CID 6088:(FDA) 6084:U.S. 6063:(PDF) 6056:(PDF) 5849:S2CID 5806:S2CID 5755:(PDF) 5744:(PDF) 5534:S2CID 5490:S2CID 5361:S2CID 5058:(PDF) 5051:(FDA) 5047:U.S. 5043:(PDF) 4968:S2CID 4822:S2CID 4732:S2CID 4530:S2CID 4426:(PDF) 4415:(PDF) 4381:S2CID 4285:S2CID 4058:S2CID 3936:S2CID 3656:S2CID 3538:S2CID 3476:S2CID 2903:S2CID 2682:(PDF) 2671:(PDF) 2601:(emc) 2000:6,300 1980:6,500 1717:1,000 1714:2,000 1464:1,451 1358:, or 1296:MAOIs 1294:, or 1235:, or 1072:in a 811:InChI 767:JSmol 614:ChEBI 539:49516 471:54840 463:54841 351:Liver 18945:ANTI 18562:HZ-2 18116:BNTX 17399:CTOP 17395:CTAP 16272:AZIK 16261:MDMA 15750:PPPA 15493:SRIs 15482:SERT 15026:PPPA 14783:NRIs 14283:MDPV 14130:DRIs 14045:here 14043:See 14020:here 14018:See 14007:TRPs 13838:CFTR 13765:DIDS 13606:ENaC 13527:mint 12915:K2Ps 12786:GIRK 12631:GIRK 12497:IRKs 12213:hERG 11561:Z944 11487:Z160 10947:MTPG 10942:MSOP 10937:MPPG 10932:MAP4 10927:CPPG 10910:-AP4 10897:DCPG 10851:MTPG 10846:MSOP 10841:MPPG 10831:MAP4 10826:CPPG 10811:-AP4 10764:MTPG 10759:MSOP 10754:MPPG 10749:MAP4 10744:CPPG 10734:-AP4 10692:MTPG 10687:MSOP 10682:MPPG 10677:MAP4 10672:CPPG 10662:MPEP 10630:-AP4 10563:MCPG 10543:EGLU 10422:MCPG 10402:EGLU 10315:BINA 10268:MTEP 10263:MPEP 10211:MCPG 10191:CTEP 10154:DHPG 10144:CHPG 10129:ACPD 10095:MCPG 10020:DHPG 10015:ACPD 9854:MPEP 9794:-αAA 9652:Zinc 9479:PCPr 9449:NEFA 9135:PNQX 9065:DNQX 9052:CNQX 8985:PPDA 8970:PBPD 8840:DHEA 8825:DHEA 8735:DHPG 8686:ACPD 8676:ACBD 8640:NMDA 8606:AMAA 8506:NBQX 8481:GAMS 8476:DNQX 8466:CNQX 8384:ATPA 8379:AMPA 8217:PNQX 8212:NBQX 8187:GAMS 8177:DNQX 8167:CNQX 8152:ATPO 8112:PEPA 7970:BOAA 7965:AMPA 7763:SAMe 7203:TCAs 7188:and 6923:NRIs 6785:N06A 6692:(NE) 6674:(DA) 6409:ADHD 6369:2020 6353:PMID 6315:PMID 6280:PMID 6207:PMID 6170:ISBN 6147:PMID 6100:2018 6017:2024 5991:2009 5951:ISBN 5880:ISBN 5841:PMID 5798:PMID 5763:2023 5723:PMID 5669:PMID 5634:PMID 5585:PMID 5526:PMID 5482:PMID 5470:1660 5444:PMID 5392:PMID 5353:PMID 5317:PMID 5273:PMID 5238:PMID 5192:PMID 5149:PMID 5104:2017 5066:2017 5017:PMID 4960:PMID 4919:PMID 4895:2011 4863:PMID 4814:PMID 4782:2013 4748:2022 4698:PMID 4649:PMID 4613:PMID 4565:PMID 4522:PMID 4468:PMID 4434:2024 4397:2024 4373:PMID 4334:PMID 4277:PMID 4241:PMID 4192:PMID 4156:PMID 4107:PMID 4050:PMID 4013:ISBN 3990:PMID 3928:PMID 3884:PMID 3848:PMID 3816:2019 3804:NIMH 3786:2018 3752:PMID 3720:2024 3690:2024 3648:PMID 3614:2019 3575:ISBN 3554:2023 3530:PMID 3492:2023 3468:PMID 3426:PMID 3382:PMID 3328:PMID 3292:PMID 3243:PMID 3208:2017 3174:PMID 3122:PMID 3073:PMID 3024:PMID 2992:2019 2943:PMID 2895:PMID 2825:2013 2784:2013 2731:2013 2690:2022 2654:2020 2613:2022 2583:2023 2549:2023 2520:2020 2300:and 2144:GIRK 2137:ADHD 2133:NR2B 2117:NMDA 2056:, a 1996:hERG 1749:5-HT 1726:5-HT 1707:5-HT 1684:5-HT 1661:5-HT 1638:5-HT 1611:NMDA 1588:GABA 1404:SERT 1381:Site 1324:and 1248:hERG 1223:for 1187:and 1032:and 1014:RCTs 983:and 948:and 586:KEGG 558:UNII 491:7118 320:data 181:Oral 86:AHFS 19040:ECG 19035:EGC 18151:EGC 18146:ECG 17825:FIT 17429:EGC 17424:ECG 16267:APP 14772:NET 14490:BTQ 14329:CFT 14119:DAT 13269:FBT 12702:ATP 12522:ATP 10149:DFB 9017:ACC 8925:CPP 8895:AP7 8706:CCG 8346:KAR 7726:), 7614:MAO 7554:MAO 7055:SMS 6489:CNS 6420:CNS 6272:doi 6199:doi 6137:PMC 6127:doi 5872:doi 5833:doi 5790:doi 5748:FDA 5713:PMC 5705:doi 5661:doi 5624:PMC 5616:doi 5575:PMC 5565:doi 5518:doi 5514:232 5474:doi 5434:PMC 5426:doi 5422:160 5388:232 5345:doi 5307:doi 5303:114 5265:doi 5228:doi 5184:doi 5139:PMC 5131:doi 5127:226 5007:PMC 4999:doi 4995:156 4950:doi 4909:PMC 4899:doi 4853:doi 4806:doi 4724:doi 4688:PMC 4680:doi 4641:doi 4603:PMC 4595:doi 4557:doi 4553:112 4512:hdl 4502:doi 4498:112 4460:doi 4365:doi 4324:PMC 4316:doi 4269:doi 4231:PMC 4223:doi 4184:doi 4146:PMC 4138:doi 4097:PMC 4089:doi 4042:doi 3980:PMC 3970:doi 3918:doi 3876:doi 3840:doi 3836:114 3744:doi 3740:178 3640:doi 3522:doi 3460:doi 3416:PMC 3372:PMC 3362:doi 3320:doi 3282:PMC 3274:doi 3270:128 3235:doi 3231:162 3164:PMC 3156:doi 3112:PMC 3104:doi 3063:PMC 3055:doi 3016:doi 2935:doi 2887:doi 2542:FDA 2232:max 2107:or 2048:or 1952:3.2 1597:200 1538:KOR 1523:300 1509:DOR 1495:422 1482:MOR 1460:DAT 1433:NET 1385:ATX 1320:or 675:EPA 453:CID 340:98% 283:POM 214:WHO 19664:: 19506:D 18861:, 18857:, 18853:, 16434:• 16430:• 16426:• 16422:• 16418:• 16414:• 16391:; 16259:, 16255:, 16209:, 16205:, 16201:, 16197:, 16193:, 16124:, 16120:, 16116:, 16112:, 16098:, 16084:, 16080:, 16076:, 16072:, 16068:, 16064:, 15464:, 15460:, 15456:, 15452:, 15448:, 15407:, 15393:, 15379:, 15375:, 15371:, 14067:• 13568:, 13564:, 13295:, 12869:Ca 12867:BK 12837:Ca 12835:BK 12812:Ca 12472:7) 12434:7) 11674:): 11389:; 11314:; 11284:; 10977:• 10973:• 10912:; 10863:; 10652:; 10570:; 10434:; 10377:; 10233:; 10176:; 9766:; 9654:; 9637:; 9615:; 9551:; 9179:; 9147:; 8997:; 8815:24 8810:; 8793:; 8662:; 8549:, 8538:; 8426:; 8330:; 8260:, 8249:; 8002:; 7840:: 7779:, 7734:)) 7730:(T 7722:(T 7708:, 7689:, 7685:, 7681:, 7677:, 7673:, 6449:, 6445:, 6441:, 6347:. 6311:22 6309:. 6286:. 6278:. 6268:58 6266:. 6213:. 6205:. 6195:16 6193:. 6145:. 6135:. 6121:. 6117:. 6082:. 6071:^ 6033:. 6007:. 5973:. 5949:. 5878:. 5847:. 5839:. 5829:44 5827:. 5804:. 5796:. 5786:31 5784:. 5771:^ 5750:. 5746:. 5721:. 5711:. 5701:35 5699:. 5695:. 5681:^ 5667:. 5657:20 5655:. 5632:. 5622:. 5610:. 5606:. 5583:. 5573:. 5559:. 5555:. 5532:. 5524:. 5512:. 5488:. 5480:. 5468:. 5456:^ 5442:. 5432:. 5420:. 5416:. 5404:^ 5386:. 5367:. 5359:. 5351:. 5341:86 5339:. 5315:. 5301:. 5297:. 5285:^ 5271:. 5261:26 5259:. 5236:. 5224:27 5222:. 5218:. 5204:^ 5190:. 5180:14 5178:. 5161:^ 5147:. 5137:. 5125:. 5121:. 5090:. 5053:. 5045:. 5029:^ 5015:. 5005:. 4993:. 4989:. 4966:. 4958:. 4946:42 4944:. 4940:. 4917:. 4907:. 4893:. 4889:. 4875:^ 4861:. 4849:19 4847:. 4843:. 4820:. 4812:. 4802:24 4800:. 4768:. 4764:. 4738:. 4730:. 4718:. 4696:. 4686:. 4676:19 4670:. 4647:. 4637:33 4635:. 4611:. 4601:. 4589:. 4571:. 4563:. 4551:. 4528:. 4520:. 4510:. 4496:. 4492:. 4480:^ 4466:. 4456:21 4454:. 4442:^ 4417:. 4387:. 4379:. 4371:. 4361:87 4359:. 4355:. 4332:. 4322:. 4312:79 4310:. 4306:. 4283:. 4275:. 4265:25 4263:. 4239:. 4229:. 4219:23 4217:. 4213:. 4190:. 4180:27 4178:. 4154:. 4144:. 4134:62 4132:. 4128:. 4105:. 4095:. 4085:62 4083:. 4079:. 4056:. 4048:. 4038:29 4036:. 3988:. 3978:. 3966:12 3964:. 3960:. 3948:^ 3934:. 3926:. 3914:28 3912:. 3908:. 3896:^ 3882:. 3872:69 3870:. 3846:. 3834:. 3806:. 3802:. 3776:. 3772:. 3750:. 3738:. 3710:. 3706:. 3680:. 3676:. 3654:. 3646:. 3636:35 3622:^ 3604:. 3600:. 3589:^ 3562:^ 3544:. 3536:. 3528:. 3518:30 3516:. 3512:. 3500:^ 3482:. 3474:. 3466:. 3456:15 3454:. 3450:. 3438:^ 3424:. 3412:30 3410:. 3406:. 3394:^ 3380:. 3370:. 3358:11 3356:. 3352:. 3340:^ 3326:. 3316:26 3314:. 3290:. 3280:. 3268:. 3264:. 3241:. 3229:. 3210:. 3194:. 3172:. 3162:. 3152:23 3150:. 3146:. 3134:^ 3120:. 3110:. 3100:23 3098:. 3094:. 3071:. 3061:. 3051:62 3049:. 3045:. 3022:. 3012:27 3010:. 2978:. 2955:^ 2941:. 2931:16 2929:. 2915:^ 2901:. 2893:. 2883:44 2881:. 2833:^ 2811:. 2792:^ 2770:. 2739:^ 2717:. 2698:^ 2673:. 2640:. 2621:^ 2599:. 2540:. 2536:. 2506:. 2450:. 2320:. 2175:, 2168:, 2155:ir 2139:. 1989:ND 1984:ND 1974:ir 1965:ND 1960:ND 1950:ir 1941:ND 1936:ND 1926:ir 1793:2A 1765:ND 1760:ND 1742:ND 1737:ND 1700:ND 1695:ND 1686:1D 1677:ND 1672:ND 1663:1B 1654:ND 1649:ND 1640:1A 1627:ND 1622:ND 1580:ND 1575:ND 1557:ND 1551:95 1529:ND 1518:ND 1501:ND 1473:ND 1468:ND 1453:92 1424:ND 1419:43 1414:77 1354:, 1350:, 1346:, 1342:, 1290:, 1261:. 1254:50 1252:IC 1231:, 1167:, 1076:. 1048:, 1020:. 964:. 897:, 886:. 740:21 734:17 407:)- 403:(3 305:EU 290:US 277:UK 266:CA 253:BR 246:S4 240:AU 159:AU 127:US 72:)- 19640:: 19487:: 19398:2 19324:2 19246:2 19238:2 19230:2 19226:2 19218:2 18865:) 18808:) 18804:( 17101:) 17097:( 16506:) 16470:e 16463:t 16456:v 16263:) 16213:) 16128:) 16102:) 16088:) 15962:) 15499:) 15490:( 15468:) 15411:) 15397:) 15383:) 15238:) 14789:) 14780:( 14136:) 14127:( 14102:e 14095:t 14088:v 13572:) 13529:) 13525:( 13299:) 13291:( 13267:p 12810:K 12700:K 12520:K 12470:v 12432:v 12217:v 11978:: 11666:2 11664:α 11533:: 11520:: 11502:: 11444:: 11319:: 11074:: 11068:: 11018:e 11011:t 11004:v 10908:L 10881:8 10809:L 10782:7 10732:L 10710:6 10628:L 10606:4 10457:3 10299:2 10113:5 9999:1 9968:e 9961:t 9954:v 9890:) 9886:( 9792:D 9058:D 8848:) 8844:( 8835:) 8831:( 8817:S 8769:L 8761:L 8728:D 8720:D 8712:D 8669:D 8623:L 8553:) 8264:) 7917:e 7910:t 7903:v 7799:) 7783:) 7775:( 7765:) 7732:4 7724:3 7718:( 7712:) 7704:( 7693:) 7669:( 7616:B 7556:A 6787:) 6783:( 6773:e 6766:t 6759:v 6527:2 6525:α 6478:) 6474:( 6453:) 6437:( 6400:e 6393:t 6386:v 6371:. 6321:. 6294:. 6274:: 6221:. 6201:: 6178:. 6153:. 6129:: 6123:2 6102:. 6019:. 5993:. 5959:. 5888:. 5874:: 5855:. 5835:: 5812:. 5792:: 5765:. 5729:. 5707:: 5675:. 5663:: 5640:. 5618:: 5612:4 5591:. 5567:: 5561:7 5540:. 5520:: 5496:. 5476:: 5450:. 5428:: 5398:. 5347:: 5323:. 5309:: 5279:. 5267:: 5244:. 5230:: 5198:. 5186:: 5155:. 5133:: 5106:. 5086:i 5068:. 5023:. 5001:: 4974:. 4952:: 4925:. 4901:: 4869:. 4855:: 4828:. 4808:: 4784:. 4770:4 4750:. 4726:: 4704:. 4682:: 4655:. 4643:: 4619:. 4597:: 4559:: 4536:. 4514:: 4504:: 4474:. 4462:: 4436:. 4399:. 4367:: 4340:. 4318:: 4291:. 4271:: 4247:. 4225:: 4198:. 4186:: 4162:. 4140:: 4113:. 4091:: 4064:. 4044:: 4021:. 3996:. 3972:: 3942:. 3920:: 3890:. 3878:: 3854:. 3842:: 3818:. 3788:. 3758:. 3746:: 3722:. 3692:. 3662:. 3642:: 3616:. 3583:. 3556:. 3524:: 3494:. 3462:: 3432:. 3388:. 3364:: 3334:. 3322:: 3298:. 3276:: 3249:. 3237:: 3180:. 3158:: 3128:. 3106:: 3079:. 3057:: 3030:. 3018:: 2994:. 2949:. 2937:: 2909:. 2889:: 2827:. 2786:. 2733:. 2692:. 2656:. 2615:. 2585:. 2551:. 2522:. 2353:R 2314:N 2306:N 2294:N 2276:C 2274:( 2264:N 2260:N 2252:N 2248:1 2230:t 2193:i 2191:G 2186:1 2184:A 2179:2 2177:D 2172:2 2170:α 2165:2 2163:M 2123:2 2121:α 2111:1 2109:α 2104:1 2102:D 2013:i 1972:K 1948:K 1924:K 1907:1 1905:H 1888:2 1886:D 1869:1 1867:D 1850:2 1848:M 1831:1 1829:M 1812:1 1810:β 1791:α 1774:1 1772:α 1751:7 1728:6 1709:2 1590:A 1566:1 1564:σ 1448:3 1443:5 1328:2 1326:β 1308:1 1306:α 1241:N 1012:( 975:2 973:α 769:) 746:O 743:N 737:H 731:C 677:) 673:( 409:N 405:R 307:: 292:: 279:: 255:: 242:: 161:: 88:/ 78:o 74:N 70:R 68:(

Index



Trade names
others
AHFS
Drugs.com
Monograph
MedlinePlus
a603013
License data
DailyMed
Atomoxetine
Pregnancy
category

Routes of
administration

Oral
Drug class
Selective norepinephrine reuptake inhibitor
ATC code
N06BA09
WHO
Legal status
S4
Class C1
℞-only
POM
WARNING
Pharmacokinetic
Bioavailability
Protein binding
Metabolism

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.