68:. He returned to Belfast in 1954 as a reader in physiology at Queen's University. In the department of physiology he had four close colleagues, namely Archibald David Mant Greenfield (1917–2005), Ian Campbell Roddie (1928–2011), Walter Ernest "Darty" Glover (1932–2017), and Robert Ford "Bob" Whelan (1922–1984), who later became deans of medical schools. In 1956 Shepherd received a D.Sc. from Queen's University Belfast. In 1957 he emigrated with his family to the United States and joined the staff of the Mayo Clinic, where he remained until his retirement in 1989.
32:) was a British-American cardiologist, medical researcher in cardiovascular physiology, and medical school dean. His research on the regulation of the cardiovascular system included "classic studies on reflex control of the circulation, haemodynamic responses to heat stress and exercise, and mechanisms of vasodilation."
104:
Two of his brothers and five among his nephews and nieces became physicians. In 1945 he married Helen Mary
Johnston, who died in 1987. They had a daughter, Gillian, and a son, Roger, both of whom became physicians. Upon his death, John T. Shepherd was survived by his second wife, Marion, as well as
97:
and with scientists from the Soviet Union. From 1965 to 1974 he was the chair of the
Committee on Space Medicine of the U.S. National Academy of Sciences. From 1975 to 1976 he was the president of the
1088:
71:
From 1966 to 1974 he was a professor and the chair of the department of physiology and biophysics with a joint appointment at the Mayo
Medical School (now named the
630:
Cohen, Richard A.; Shepherd, John T.; Vanhoutte, Paul M. (1983). "Inhibitory Role of the
Endothelium in the Response of Isolated Coronary Arteries to Platelets".
1103:
1098:
774:
Mancia, Giuseppe; LĂĽscher, Thomas F.; Shepherd, John T.; Noll, George; Grassi, Guido M. (2007). "Cardiovascular
Regulation: Basic Considerations".
61:
1053:
1048:
1093:
105:
his daughter and son from his first marriage, and "four step-children, five grandchildren, eight step-grandchildren and a great-grandson."
78:
He helped to train more than 100 research fellows. He was the author or co-author of several books and more than 300 scientific articles.
385:
Strandell, Tore; Shepherd, John T. (2009). "The Effect in Humans of
Increased Sympathetic Activity on the Blood Flow to Active Muscles".
529:
Mancia, G.; Shepherd, J. T.; Donald, D. E. (1976). "Interplay among carotid sinus, cardiopulmonary, and carotid body reflexes in dogs".
1063:
1058:
49:
710:
Shepherd, J.; Katusic, Z. S.; Vedernikov, Y.; Vanhoutte, P. M. (1991). "Mechanisms of coronary vasospasm: Role of endothelium".
791:
60:, he became a staff member of the department of the physiology of Queen's University, Belfast. There in 1951 he received the
72:
457:
Zitnik, Ralph S.; Burchell, Howard B.; Shepherd, John T. (1969). "Hemodynamic effects of inhalation of ammonia in man".
165:"A quantitative study of the response to acetylcholine and histamine of the blood vessels of the human hand and forearm"
846:
206:
Roddie IC; Shepherd JT; Whelan RF (1956). "Sympathetic cholinergic fibres producing vasodilatation in forearm skin".
934:
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Shepherd, J. T.; Bergan, J. J.; Cohen, R. A.; Hawiger, J. J.; Hillis, L. D.; Katzen, B. T.; Mohr, J. P. (1994).
1073:
1068:
880:
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344:"Circulatory effects of stimulating the carotid arterial stretch receptors in man at rest and during exercise"
45:
560:"Inhibition of sympathetic neurotransmission in canine blood vessels by adenosine and adenine nucleotides"
1108:
86:
98:
82:
229:"The contribution of constrictor and dilator nerves to the skin vasodilatation during body heating"
64:
He was awarded in 1953 a
Fulbright Scholarship for one year to do cardiovascular research at the
601:
Donald, David E.; Shepherd, John T. (1979). "Cardiac receptors: Normal and disturbed function".
1043:
1038:
639:
29:
8:
860:. New York: Published for the American Physiological Society by Oxford University Press.
643:
313:
Donald DE; Shepherd JT (1963). "Response to
Exercise in Dogs with Cardiac Denervation".
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416:"Evidence for a Dilator Action of Carbon Dioxide on the Pulmonary Vessels of the Cat"
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869:. Afton, Minnesota: Afton Historical Society Press; foreword by Walter F. Mondale
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272:"Blood pressure during supine exercise in idiopathic orthostatic hypotension"
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488:"Venous relaxation caused by acetylcholine acting on the sympathetic nerves"
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Physiology of the circulation in human limbs in health and disease
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in 1948. After completing his internship and residency at the
226:
205:
53:
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Verhaeghe, R. H.; Vanhoutte, P. M.; Shepherd, J. T. (1977).
94:
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Exercise: regulation and integration of multiple systems
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Duff F; Greenfield AD; Shepherd JT; Thompson ID (1953).
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122:"Evaluation of Treatment in Intermittent Claudication"
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Emigrants from
Northern Ireland to the United States
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312:
856:Rowell, Loring G.; Shepherd, John T., eds. (1996).
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864:
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838:Human cardiovascular system: facts and concepts
817:Marshall, Robert J.; Shepherd, John T. (1968).
741:"Report of the Task Force on Vascular Medicine"
835:Shepherd, John T.; Vanhoutte, Paul M. (1979).
826:Shepherd, John T.; Vanhoutte, Paul M. (1975).
600:
673:Journal of the American College of Cardiology
413:
270:Marshall RJ; Schirger A; Shepherd JT (1961).
712:Journal of Molecular and Cellular Cardiology
75:) and the Mayo Graduate School of Medicine.
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414:Viles, Peter H.; Shepherd, John T. (1968).
486:Vanhoutte, P. M.; Shepherd, J. T. (1973).
227:Roddie IC; Shepherd JT; Whelan RF (1957).
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342:BevegĂĄrd, B. S.; Shepherd, J. T. (1966).
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81:Shepherd was elected in 1951 a member of
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1104:Academics of Queen's University Belfast
1018:"The 50 best Mayo Clinic doctors. Ever"
830:. London; Philadelphia: W. B. Saunders.
44:, John T. Shepherd studied medicine at
1031:
1016:Parmar, Arundhati (22 December 2011).
971:
819:Cardiac function in health and disease
952:
921:Royal College of Physicians of London
1099:Alumni of Queen's University Belfast
1054:21st-century British medical doctors
1049:20th-century British medical doctors
1094:People educated at Campbell College
73:Mayo Clinic Alix School of Medicine
13:
603:The American Journal of Cardiology
531:The American Journal of Physiology
459:The American Journal of Cardiology
399:10.1111/j.0954-6820.1967.tb12622.x
315:The American Journal of Physiology
14:
1120:
1009:
348:Journal of Clinical Investigation
1064:21st-century American physicians
1059:20th-century American physicians
867:Inside the Mayo clinic: a memoir
327:10.1152/ajplegacy.1963.205.2.393
58:Royal Victoria Hospital, Belfast
40:After graduation from Belfast's
812:. Philadelphia: W. B. Saunders.
543:10.1152/ajplegacy.1976.230.1.19
62:research medical degree of M.D.
974:"John T. Shepherd (1919–2011)"
927:
821:. Philadelphia: W. B Saunders.
669:"The heart as a sensory organ"
245:10.1113/jphysiol.1957.sp005775
181:10.1113/jphysiol.1953.sp004883
1:
888:
686:10.1016/S0735-1097(85)80533-7
990:10.1113/jphysiol.2011.223792
935:"John T. Shepherd 1919–2011"
784:10.1007/978-1-84628-715-2_73
724:10.1016/0022-2828(91)90031-G
615:10.1016/0002-9149(79)90216-9
471:10.1016/0002-9149(69)90402-0
85:and in 1977 a fellow of the
35:
28:, Ireland – 4 October 2011,
7:
113:
87:Royal College of Physicians
10:
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879:: CS1 maint: postscript (
865:Shepherd, John T. (2003).
808:Shepherd, John T. (1963).
667:Shepherd, John T. (1985).
99:American Heart Association
46:Queen's University Belfast
978:The Journal of Physiology
841:. New York: Raven Press.
233:The Journal of Physiology
208:The Journal of Physiology
169:The Journal of Physiology
83:The Physiological Society
917:"John Thompson Shepherd"
801:
387:Acta Medica Scandinavica
120:Shepherd, J. T. (1950).
828:Veins and their control
776:Cardiovascular Medicine
758:10.1161/01.CIR.89.1.532
652:10.1126/science.6574604
577:10.1161/01.RES.40.2.208
505:10.1161/01.res.32.2.259
433:10.1161/01.RES.22.3.325
138:10.1136/bmj.2.4694.1413
1084:American physiologists
1079:American cardiologists
1022:MedCity News, MinnPost
972:Joyner, M. J. (2011).
778:. pp. 1525–1539.
289:10.1161/01.cir.24.1.76
22:John Thompson Shepherd
1074:British physiologists
1069:British cardiologists
109:Selected publications
984:(Pt 24): 5927–5928.
564:Circulation Research
492:Circulation Research
420:Circulation Research
30:Rochester, Minnesota
644:1983Sci...221..273C
132:(4694): 1413–1418.
1109:Mayo Clinic people
948:: 56. Winter 2011.
16:American physician
793:978-1-84628-188-4
638:(4607): 273–274.
360:10.1172/JCI105317
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745:Circulation
718:: 125–131.
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276:Circulation
66:Mayo Clinic
1033:Categories
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875:cite book
282:: 76–81.
36:Biography
703:38160966
594:16215262
335:14058123
298:13767236
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640:Bibcode
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302:S2CID
93:with
54:M.Ch.
881:link
843:ISBN
788:ISBN
763:PMID
728:PMID
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