273:
Halliwell served as the NUS's first Deputy
President (Research and Technology) in 2006–15, founding the Graduate School for Integrative Sciences and Engineering, and overseeing a doubling in the university's research grants. He was subsequently appointed Senior Advisor to the NUS President. He chairs
396:
in 2011. Other awards include a lifetime achievement award from the
American Society for Free Radical Biology and Medicine (2008) and the Ken Bowman Research Award from the Canadian Institute of Cardiovascular Sciences (2011).
1051:
258:
in 1974, remaining there until 2000, rising to the position of professor of medical biochemistry in the
Division of Pharmacology. He also simultaneously held a visiting professorship at the
503:
Halliwell, Barry; Gutteridge, John MC; Aruoma, Okezie I (1987). "The deoxyribose method: A simple "test-tube" assay for determination of rate constants for reactions of hydroxyl radicals".
1041:
325:, and investigated the involvement of metal ions, including iron and zinc, in this process, as well as the protective effect of their sequestration. He has also worked on
344:
and other brain disorders. His interests include the characterisation of redox biomarkers for the identification of human diseases, molecular nutrition, the role of
289:, is considered "an authoritative text in the field". His work is highly cited; in 2011, eight of his research articles had each received over a thousand citations.
534:
Foyer, Christine H.; Halliwell, Barry (1976). "The presence of glutathione and glutathione reductase in chloroplasts: a proposed role in ascorbic acid metabolism".
286:
1026:
860:
Prominent
Behavioural Scientist Ho Teck Hua to Head NUS Research: Current head, acclaimed biochemist Barry Halliwell, to be senior advisor to NUS President
387:
266:(NUS), he moved there in 2000 as chair of the biochemistry department. As of 2018 he is a professor in the department of biochemistry at the NUS
1036:
1021:
191:
1031:
223:
226:(honours) in biochemistry. He was also awarded the Rose Prize for the best final papers of any candidate in biological sciences. His
858:
886:
935:
438:
424:
392:
211:
746:
263:
195:
113:
267:
259:
234:
and Vernon Butt; his thesis was entitled "The biochemistry of plant peroxisomes" (1973). He was later awarded a
340:
As of 2018, his research focuses on the role of free radicals and antioxidants in human disease, particularly
317:. He subsequently focused on the role of free radicals in human diseases, demonstrating the toxicity of the
1046:
306:
275:
179:
592:
255:
251:
109:
505:
416:
356:, the development of drugs to prevent oxidative cell damage, the chemical nature of antioxidants
194:. He moved to Singapore in 2000, and served as Deputy President (Research and Technology) of the
1016:
374:
341:
198:(2006–15), where (as of 2018) he continues to hold a Tan Chin Tuan Centennial professorship.
126:
1011:
239:
231:
227:
215:
64:
8:
457:
207:
44:
242:
for his work on the biochemistry of free radical reactions in plant and animal systems.
988:
830:
794:
778:
659:
Barry
Halliwell (2004), "How I became a biochemist: The wanderings of a free radical",
622:
609:
561:
479:
452:
971:
952:
903:
838:
813:
786:
761:
712:
678:
627:
553:
522:
518:
484:
434:
420:
326:
314:
183:
141:
798:
565:
210:, Lancashire in 1949, Halliwell was educated at Preston Grammar School. He attended
980:
944:
895:
822:
770:
704:
668:
617:
601:
545:
536:
514:
502:
474:
466:
345:
318:
219:
984:
826:
774:
186:
metabolism in plants and animals, named for the three principal discoverers, with
361:
302:
187:
151:
899:
759:
Dennis
Normile (2002), "Can Money Turn Singapore into a Biotech Juggernaut?",
673:
1005:
333:
and to quantify the damage they cause to DNA. He has also researched dietary
298:
969:
Lempinen, Edward W.; Ham, Becky (2012), "AAAS Members
Elected as Fellows",
956:
907:
842:
790:
716:
682:
631:
557:
175:
99:
948:
708:
605:
526:
488:
372:
and neuro-degenerative diseases and ageing in humans and in the nematode
334:
310:
78:
992:
834:
613:
782:
549:
322:
301:
in biological systems. His earliest research was in plants, where with
167:
470:
82:
178:
metabolism in both animals and plants. His name is included in the "
933:
Shazib
Pervaiz (2011), "Redox pioneer: professor Barry Halliwell",
811:
Dennis
Normile (2012), "Flocking to Asia For a Shot at Greatness",
533:
1052:
Fellows of the
American Association for the Advancement of Science
740:
453:"Oxygen toxicity, oxygen radicals, transition metals and disease"
171:
590:
Donald R. Ort; Aleel K. Grennan (2011), "Founders Review 2011",
369:
120:
589:
329:
species. He developed methods to measure free radical levels
74:
884:
Halliwell, B. (2013), "An interview with Barry Halliwell",
390:
in 2012. He was dubbed a "Research Pioneer" by the journal
309:(also known as the Foyer–Halliwell–Asada pathway) by which
270:, where he holds a Tan Chin Tuan Centennial professorship.
235:
262:, United States (1995–99). After a 1998 sabbatical at the
450:
250:
After leaving Oxford, Halliwell briefly lectured at the
230:
in plant biochemistry was also at Oxford, supervised by
1042:
Academic staff of the National University of Singapore
368:
and their application to human disease, particularly
388:
American Association for the Advancement of Science
695:Del Rio, L A (24 June 2011), "Christine H Foyer",
297:Halliwell is known for his work on the control of
1003:
879:
877:
254:(1973–74). He took up a position as lecturer at
658:
932:
810:
758:
174:and university administrator, specialising in
874:
585:
583:
968:
804:
752:
201:
580:
433:(2nd edn) (Oxford University Press, 1984)
928:
926:
924:
922:
920:
918:
916:
883:
735:
733:
731:
729:
727:
725:
672:
654:
652:
650:
648:
646:
644:
642:
640:
621:
478:
1027:Alumni of St Catherine's College, Oxford
853:
851:
400:
360:, methods for the specific detection of
694:
348:ions as promoters of radical reactions
1004:
913:
722:
637:
386:Halliwell was elected a fellow of the
305:and others in 1976, he discovered the
848:
413:Free Radicals in Biology and Medicine
411:Barry Halliwell, John MC Gutteridge.
381:
283:Free Radicals in Biology and Medicine
245:
166:(born 18 October 1949) is an English
127:The Biochemistry of Plant Peroxisomes
1022:Scientists from Preston, Lancashire
451:Halliwell B; Gutteridge JM (1984).
13:
1037:Academics of King's College London
1032:Alumni of the University of London
936:Antioxidants & Redox Signaling
887:Trends in Pharmacological Sciences
393:Antioxidants & Redox Signaling
14:
1063:
182:" pathway, a cellular process of
16:Biochemistry researcher, academic
747:National University of Singapore
264:National University of Singapore
196:National University of Singapore
114:National University of Singapore
962:
268:Yong Loo Lin School of Medicine
260:University of California, Davis
688:
364:and reactive nitrogen species
1:
985:10.1126/science.338.6111.1166
827:10.1126/science.337.6099.1162
775:10.1126/science.297.5586.1470
573:
863:, newswise.com, 1 March 2015
519:10.1016/0003-2697(87)90222-3
7:
307:glutathione–ascorbate cycle
292:
276:Biomedical Research Council
10:
1068:
900:10.1016/j.tips.2013.04.002
674:10.1080/15216540400013911
157:
147:
137:
119:
105:
95:
88:
70:
60:
52:
30:
23:
202:Early life and education
697:Antioxid. Redox Signal.
506:Analytical Biochemistry
417:Oxford University Press
218:(1968–71), achieving a
431:Chloroplast Metabolism
375:Caenorhabditis elegans
252:Portsmouth Polytechnic
212:St Catherine's College
949:10.1089/ars.2010.3518
709:10.1089/ars.2011.4007
606:10.1104/pp.110.900401
401:Selected publications
287:John M. C. Gutteridge
256:King's College London
180:Foyer–Halliwell–Asada
110:King's College London
240:University of London
232:Frederick R. Whatley
216:University of Oxford
65:University of Oxford
1047:English biochemists
458:Biochemical Journal
342:Alzheimer's disease
45:Preston, Lancashire
550:10.1007/BF00386001
382:Awards and honours
321:, a metabolite of
285:, co-written with
246:Career and writing
979:(6111): 1166–71,
821:(6099): 1162–66,
769:(5586): 1470–73,
497:Research articles
471:10.1042/bj2190001
429:Barry Halliwell.
327:reactive nitrogen
315:hydrogen peroxide
184:hydrogen peroxide
161:
160:
142:Frederick Whatley
138:Academic advisors
90:Scientific career
1059:
996:
995:
966:
960:
959:
930:
911:
910:
881:
872:
871:
870:
868:
855:
846:
845:
808:
802:
801:
756:
750:
749:
737:
720:
719:
692:
686:
685:
676:
656:
635:
634:
625:
593:Plant Physiology
587:
569:
530:
492:
482:
346:transition metal
319:hydroxyl radical
313:remove damaging
148:Notable students
133:
40:
38:
21:
20:
1067:
1066:
1062:
1061:
1060:
1058:
1057:
1056:
1002:
1001:
1000:
999:
967:
963:
931:
914:
882:
875:
866:
864:
857:
856:
849:
809:
805:
757:
753:
742:Barry Halliwell
739:
738:
723:
693:
689:
657:
638:
588:
581:
576:
403:
384:
362:reactive oxygen
303:Christine Foyer
295:
248:
204:
188:Christine Foyer
164:Barry Halliwell
152:Christine Foyer
131:
112:
61:Alma mater
48:
42:
41:18 October 1948
36:
34:
26:
25:Barry Halliwell
17:
12:
11:
5:
1065:
1055:
1054:
1049:
1044:
1039:
1034:
1029:
1024:
1019:
1014:
998:
997:
961:
943:(9): 1761–66,
912:
873:
847:
803:
751:
721:
703:(8): 2383–91,
687:
636:
578:
577:
575:
572:
571:
570:
531:
494:
493:
442:
441:
427:
402:
399:
383:
380:
294:
291:
281:His textbook,
247:
244:
203:
200:
159:
158:
155:
154:
149:
145:
144:
139:
135:
134:
123:
117:
116:
107:
103:
102:
97:
93:
92:
86:
85:
72:
71:Known for
68:
67:
62:
58:
57:
54:
50:
49:
43:
32:
28:
27:
24:
15:
9:
6:
4:
3:
2:
1064:
1053:
1050:
1048:
1045:
1043:
1040:
1038:
1035:
1033:
1030:
1028:
1025:
1023:
1020:
1018:
1017:Living people
1015:
1013:
1010:
1009:
1007:
994:
990:
986:
982:
978:
974:
973:
965:
958:
954:
950:
946:
942:
938:
937:
929:
927:
925:
923:
921:
919:
917:
909:
905:
901:
897:
894:(6): 301–02,
893:
889:
888:
880:
878:
862:
861:
854:
852:
844:
840:
836:
832:
828:
824:
820:
816:
815:
807:
800:
796:
792:
788:
784:
780:
776:
772:
768:
764:
763:
755:
748:
744:
743:
736:
734:
732:
730:
728:
726:
718:
714:
710:
706:
702:
698:
691:
684:
680:
675:
670:
667:(9): 569–70,
666:
662:
655:
653:
651:
649:
647:
645:
643:
641:
633:
629:
624:
619:
615:
611:
607:
603:
599:
595:
594:
586:
584:
579:
567:
563:
559:
555:
551:
547:
543:
539:
538:
532:
528:
524:
520:
516:
513:(1): 215–19.
512:
508:
507:
501:
500:
499:
498:
490:
486:
481:
476:
472:
468:
464:
460:
459:
454:
449:
448:
447:
446:
440:
439:0-19-854585-1
436:
432:
428:
426:
425:0-19-871748-2
422:
418:
414:
410:
409:
408:
407:
398:
395:
394:
389:
379:
377:
376:
371:
367:
363:
359:
355:
351:
347:
343:
338:
336:
332:
328:
324:
320:
316:
312:
308:
304:
300:
299:free radicals
290:
288:
284:
279:
277:
271:
269:
265:
261:
257:
253:
243:
241:
237:
233:
229:
225:
221:
217:
213:
209:
199:
197:
193:
189:
185:
181:
177:
173:
169:
165:
156:
153:
150:
146:
143:
140:
136:
129:
128:
124:
122:
118:
115:
111:
108:
104:
101:
98:
94:
91:
87:
84:
80:
76:
73:
69:
66:
63:
59:
55:
51:
46:
33:
29:
22:
19:
976:
970:
964:
940:
934:
891:
885:
865:, retrieved
859:
818:
812:
806:
766:
760:
754:
741:
700:
696:
690:
664:
660:
597:
591:
544:(1): 21–25.
541:
535:
510:
504:
496:
495:
462:
456:
444:
443:
430:
412:
405:
404:
391:
385:
373:
365:
357:
353:
349:
339:
335:antioxidants
330:
311:chloroplasts
296:
282:
280:
274:Singapore's
272:
249:
205:
176:free radical
163:
162:
125:
106:Institutions
100:Biochemistry
89:
18:
1012:1949 births
465:(1): 1–14.
415:(5th edn) (
224:First Class
79:glutathione
53:Nationality
1006:Categories
661:IUBMB Life
574:References
323:superoxide
192:Kozi Asada
168:biochemist
37:1948-10-18
238:from the
83:ascorbate
47:, England
993:41704080
957:20969479
908:23642657
843:22955812
835:23269341
799:35630201
791:12202801
717:21534879
683:15590564
632:21205629
614:41433973
600:(1): 1,
566:27896738
558:24425174
419:, 2015)
350:in vitro
293:Research
206:Born in
972:Science
814:Science
783:3832461
762:Science
623:3075777
527:3120621
489:6326753
480:1153442
445:Reviews
366:in vivo
358:in vivo
354:in vivo
331:in vivo
208:Preston
172:chemist
56:British
991:
955:
906:
867:15 May
841:
833:
797:
789:
781:
715:
681:
630:
620:
612:
564:
556:
537:Planta
525:
487:
477:
437:
423:
370:stroke
228:D.Phil
132:(1973)
130:
121:Thesis
96:Fields
989:JSTOR
831:JSTOR
795:S2CID
779:JSTOR
610:JSTOR
562:S2CID
406:Books
222:with
75:redox
953:PMID
904:PMID
869:2018
839:PMID
787:PMID
713:PMID
679:PMID
628:PMID
554:PMID
523:PMID
485:PMID
435:ISBN
421:ISBN
352:and
236:D.Sc
190:and
31:Born
981:doi
977:338
945:doi
896:doi
823:doi
819:337
771:doi
767:297
705:doi
669:doi
618:PMC
602:doi
598:155
546:doi
542:133
515:doi
511:165
475:PMC
467:doi
463:219
1008::
987:,
975:,
951:,
941:14
939:,
915:^
902:,
892:34
890:,
876:^
850:^
837:,
829:,
817:,
793:,
785:,
777:,
765:,
745:,
724:^
711:,
701:15
699:,
677:,
665:56
663:,
639:^
626:,
616:,
608:,
596:,
582:^
560:.
552:.
540:.
521:.
509:.
483:.
473:.
461:.
455:.
378:.
337:.
278:.
220:BA
214:,
170:,
81:,
77:,
983::
947::
898::
825::
773::
707::
671::
604::
568:.
548::
529:.
517::
491:.
469::
39:)
35:(
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.