245:
209:) founded the Bijvoet Centre for Biomolecular Research as a joint research institute on March 25, 1988. The goal was to create a centre for research and expertise in structural biology with an internationally recognized academic staff and an advanced instrumental and computational infrastructure, with the original task to "conduct research into the molecular structure and reactivity of chemically and biologically important, medium-sized molecules and new methods to analyze them".
235:
Originally, the institute consisted of four groups focussing on different aspects of biomolecular research: NMR Spectroscopy, Crystal- and
Structural Chemistry, Biomembranes and Modelsystems and Bio-organic Chemistry of Glycoconjugates. Since that time, the institute has evolved and diversified and,
255:
The general theme of the research in the
Bijvoet Centre is understanding how biomolecules function in the human body and in life in general and how the processes and interactions between biomolecules in living cells are affected in patients. This includes, for example, research to understand the
327:
The
Bijvoet Centre hosts a large number of both Dutch and foreign PhD, master and bachelor level students with backgrounds in Chemistry, Pharmacy, Biology, Biomedical Sciences and related fields. All research groups provide education and research training programs for master level and PhD level
359:
The
Bijvoet Centre has leading infrastructures in protein mass spectrometry, electron microscopy, high-resolution NMR spectroscopy and X-ray crystallography to analyze the structure of biomolecules and the centre participates in the European
372:, and in 2012 the institute received funding to continue their efforts in proteomics as part of the Dutch National Roadmap for Research Infrastructures. Among the extensive NMR facilities available at the institute is also a unique
298:
The institute also has technological expertise that allows for the development of novel technology to study biomolecules, like the analysis of proteins inside cells using NMR spectroscopy, novel methods for the high-throughput,
403:
and the Dutch public-private partnership COAST for the analytical sciences. On
November 5, 2015, Dutch state secretary Sander Dekker officially opened the new national NMR facility at the Bijvoet Centre.
682:
177:, which play a role in biological processes such as regulation, interaction and recognition. The Bijvoet Centre houses advanced infrastructures for the analysis of proteins and other biomolecules using
815:
315:. The centre also works on the simulation of the interactions between proteins and their interaction with drugs. To be able to predict the effect these molecules have on each other's structure,
220:) for new equipment that would contribute to societally important areas such as pharmacochemistry and biotechnology. Among the first technology to be added to the institute, was equipment for
379:-NMR spectrometer. In 2012 the institute acquired funding to obtain one of the world's first 1.2 GHz NMR spectrometers, as part of the uNMR-NL project, coordinated by prof.
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to scientists with an outstanding contribution to furthering the fields of biomolecular chemistry and/or structural biology. Previous recipients of the
Bijvoet Medal include
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114:
972:
17:
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228:) for animal studies. The official opening of the institute was on October 27, 1989, on occasion of which a symposium was organized, with Nobel prize winner
801:
387:(NWO) with 18.5M Euro, to establish a national infrastructure for ultra-high field NMR spectroscopy, a joined initiative between Utrecht University, the
261:
459:
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384:
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The
Bijvoet Centre has a staff of around 150 people, including about 10 full professors, 20 senior researchers, 50 postdocs and 50 PhD students.
838:
329:
483:
205:
Utrecht
University and the Netherlands Foundation for Chemical Research (SON, which later became the Chemical Sciences division of NWO, the
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students and, since 1992, the educational programme for PhD students of the
Bijvoet Centre has been accredited by the
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413:
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576:
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Since the
Bijvoet Centre was founded, the following people have served as scientific director of the institute:
244:
1051:"Utrecht coordinates collaboration in life sciences: 32 million euro for two large-scale research facilities"
973:"Utrecht coordinates collaboration in life sciences: 32 million euro for two large-scale research facilities"
369:
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312:
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The Hugo R. Kruytbuilding at Utrecht University houses part of the research groups of the Bijvoet Centre.
225:
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987:"Bruker Announces Installation of 527 GHz Solid State DNP-NMR Spectrometer at University of Utrecht"
308:
57:
433:
344:
304:
194:
710:
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project Instruct for integrated structural biology. Since 2005, the research group of prof. dr.
273:
311:, of a new mass spectrometer that allows the analysis of intact protein complexes, including
182:
264:
when it is mutated due to a genetic defect. Another example is the development of so-called
425:
8:
1104:
340:
186:
546:
Karin Bos (October 31, 1989). "'Bijvoet Centrum voor Biomoleculair Onderzoek' geopend".
881:
166:
162:
816:"Unieke toekenning Innovative Doctoral Programme voor Nederlands onderzoek naar eiwit"
856:
489:
437:
396:
190:
477:
365:
607:"In the Spotlight: Bijvoet Center for Biomolecular Research at Utrecht University"
429:
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in Europe to receive the prestigious Innovative Doctoral Programme grant from the
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257:
417:
348:
316:
229:
606:
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986:
738:
Frank van Geel (December 10, 2011). "Nieuwe NMR ziet ook gevouwen eiwitten".
421:
336:
292:
213:
129:
116:
167:
research on the relation between the structure and function of biomolecules
683:"Winnaar Spinozapremie 2010: Piet Gros, biomacromoleculair kristallograaf"
529:
b.k. (April 1988). "'Bijvoet-centrum voor moleculair Onderzoek' geopend".
280:
to target chemotherapeutics directly to cancer cells in a cancer patient.
753:
Marysa van den Berg (June 23, 2012). "Moeilijk te vangen fosforgroepen".
465:
380:
288:
703:"NWO Spinoza Prize for Psychologist, Astronomer, Chemist And Classicist"
687:
300:
471:
284:
1216:
236:
as of 2013, consist of seven research groups at Utrecht University.
269:
170:
149:
1158:"Friedrich Forster new scientific director of the Bijvoet Centre"
861:
MERIL - Mapping of the European Research Infrastructure Landscape
1172:"Alexandre Bonvin new scientific director of the Bijvoet Centre"
1090:"Staatssecretaris Dekker opent ultrasterke 'MRI' voor moleculen"
959:"32 miljoen euro voor twee grootschalige onderzoeksfaciliteiten"
1026:"18.5 miljoen euro voor grootschalige NMR onderzoeksfaciliteit"
514:
Joop Kessels (April 7, 1988). "SON en RUU in Bijvoet Centrum".
174:
283:
Two previous scientific directors of the institute, prof. dr.
256:
cause and potential therapeutic approaches for a disease like
938:"Miljoenen voor supermagneet en eiwit-onderzoek in De Uithof"
277:
1028:(in Dutch). Leiden University. 19 March 2012. Archived from
1193:"Marc Baldus new scientific director of the Bijvoet Center"
857:"Bijvoet Center - Bijvoet Center for Biomolecular Research"
626:"Bijvoet Centrum (1): ziektes bestrijden op atomair niveau"
335:
In 2012, the Bijvoet Centre was the first institute in the
217:
1005:"18.5 million euro for large-scale NMR research facility"
178:
918:"Albert Heck zet Utrechts eiwit-onderzoek op de kaart".
645:"Bijvoet Centrum (2): Een medicijn voor taaislijmziekte"
565:(in Dutch). Vol. 85, no. 30/31. July 27, 1989.
212:
When the institute was founded, it received 8.5 million
680:
193:. The institute is named after famous Dutch chemist
1092:(in Dutch). Universiteit Utrecht. November 6, 2015.
965:
752:
1072:"Staatssecretaris Dekker opent uNMR-NL-faciliteit"
836:
725:"Eiwit-onderzoeker Albert Heck wint Spinozapremie"
935:
804:. Royal Netherlands Academy of Arts and Sciences.
788:"Bijvoet Centrum deelt succesformule op internet"
1223:
664:"Bijvoet Centrum (3): Met lama's kanker te lijf"
385:Netherlands Organisation for Scientific Research
207:Netherlands Organisation for Scientific Research
695:
307:and the development, together with the company
260:, which is caused by misfolding of the protein
961:(in Dutch). Utrecht University. March 2, 2012.
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601:
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330:Royal Netherlands Academy of Arts and Sciences
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822:(in Dutch). November 12, 2012. Archived from
769:"Unravelling complex biomolecular structures"
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509:
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513:
926:
839:"Flinke subsidie voor Universiteit Utrecht"
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224:studies (which nowadays is mainly known as
1139:. Bijvoet Centre for Biomolecular Research
1103:Ainsworth, Susan J. (September 24, 2012).
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837:Martijn van Noppen (September 18, 2012).
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1078:(in Dutch). nieuws.nl. November 4, 2015.
979:
905:"Structural biologists share their toys"
902:
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159:Bijvoet Centre for Biomolecular Research
28:Bijvoet Centre for Biomolecular Research
18:Bijvoet Center for Biomolecular Research
1242:Research institutes established in 1988
731:
443:
36:Discovering the Molecular Basis of Life
14:
1232:Research institutes in the Netherlands
1224:
1174:. Utrecht University. 9 September 2019
681:Martijn van Calmthout (June 7, 2010).
436:as well as former scientific director
1007:. Wageningen University. 2 March 2012
849:
779:
319:has been used for these simulations.
86:Padualaan 8, Utrecht, The Netherlands
903:Callaway, Ewen (February 28, 2012).
794:
655:
636:
617:
528:
341:Marie Curie Initial Training Network
197:, who worked at Utrecht University.
936:Xander Bronkhorst (March 2, 2012).
830:
24:
1195:. Utrecht University. 6 April 2016
662:Erik Hardeman (November 1, 2012).
643:Erik Hardeman (October 31, 2012).
624:Erik Hardeman (October 30, 2012).
401:Eindhoven University of Technology
295:, in 2010 and 2017, respectively.
25:
1253:
1210:
368:in the centre is the host of the
407:
1185:
1164:
1150:
1129:
1109:Chemical & Engineering News
1096:
1082:
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1018:
997:
755:Chemisch2Weekblad Life Sciences
727:(in Dutch). NOS. June 17, 2017.
717:
922:(in Dutch). February 10, 2005.
709:. June 7, 2010. Archived from
412:The Bijvoet Centre awards the
165:. The Bijvoet Centre performs
13:
1:
1217:Website of the Bijvoet Centre
802:"Accredited research schools"
495:
370:Netherlands Proteomics Centre
354:
291:, both have received the NWO
322:
7:
577:"Bijvoet Centre - Research"
389:Radboud University Nijmegen
239:
216:(approximately 3.9 million
161:is a research institute at
52:prof. dr. Friedrich Förster
10:
1258:
786:Henk Klomp (May 6, 2013).
232:giving a keynote lecture.
200:
1117:American Chemical Society
150:www.uu.nl/science/bijvoet
145:
108:
90:
82:
74:
66:
56:
48:
40:
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309:Thermo Fisher Scientific
272:fragments, based on the
975:. Instruct. March 2012.
843:Nationale Onderwijsgids
707:www.sciencenewsline.com
345:7th Framework Programme
305:protein phosphorylation
274:single-chain antibodies
195:Johannes Martin Bijvoet
313:therapeutic antibodies
249:
1160:. Utrecht University.
882:"Bijvoet Centre - UU"
393:Wageningen University
247:
183:X-ray crystallography
775:. November 30, 2012.
444:Scientific Directors
426:Nicolaas Bloembergen
561:"Bijvoet Centrum".
548:Utrechts Nieuwsblad
187:electron microscopy
126: /
49:Scientific Director
29:
1237:Utrecht University
383:and funded by the
303:based analysis of
268:, which are small
250:
163:Utrecht University
130:52.0855°N 5.1692°E
95:Utrecht University
27:
1076:utrecht.nieuws.nl
993:. March 21, 2013.
826:on June 15, 2013.
740:Chemisch2Weekblad
713:on June 15, 2013.
563:Chemisch Weekblad
516:Chemische Courant
490:Hans Vliegenthart
458:2019-2023 :
454:Friedrich Förster
438:Hans Vliegenthart
397:Leiden University
343:programme of the
191:mass spectrometry
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16:(Redirected from
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460:Alexandre Bonvin
452:2023-now :
366:Albert J.R. Heck
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78:~10 M€ per annum
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1137:"Bijvoet Medal"
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1105:"Ivano Bertini"
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1032:on 9 April 2016
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434:Ivano Bertini
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430:Kurt Wüthrich
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422:Matthias Mann
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414:Bijvoet Medal
408:Bijvoet Medal
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1030:the original
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824:the original
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584:. Retrieved
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944:(in Dutch).
845:(in Dutch).
757:(in Dutch).
742:(in Dutch).
691:(in Dutch).
670:(in Dutch).
651:(in Dutch).
632:(in Dutch).
586:January 29,
550:(in Dutch).
535:(in Dutch).
518:(in Dutch).
488:1988-2000:
484:Rob Kaptein
482:2000-2006:
476:2006-2011:
470:2012-2016:
466:Marc Baldus
464:2016-2019:
381:Marc Baldus
374:solid state
289:Albert Heck
266:nanobullets
222:in vivo NMR
133: /
109:Coordinates
41:Established
1226:Categories
1199:2019-10-03
1178:2019-10-03
1143:2020-01-29
1122:2023-08-09
1057:2016-03-18
1053:. Instruct
1036:2016-03-18
1011:2016-03-18
884:. Instruct
688:Volkskrant
496:References
355:Facilities
301:proteomics
118:52°05′08″N
907:. Nature.
581:www.uu.nl
472:Piet Gros
323:Education
285:Piet Gros
276:found in
121:5°10′09″E
991:Azom.com
270:antibody
240:Research
171:proteins
91:Location
347:of the
201:History
146:Website
99:Utrecht
83:Address
58:Faculty
1115:(39).
888:Sep 4,
866:Sep 4,
278:llamas
175:lipids
75:Budget
920:Ublad
362:ESFRI
67:Staff
33:Motto
890:2019
868:2019
588:2020
262:CFTR
218:Euro
189:and
173:and
157:The
70:~150
44:1988
942:DUB
668:DUB
649:DUB
630:DUB
377:DNP
226:MRI
179:NMR
62:~30
1228::
1113:90
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1107:.
1074:.
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1146:.
1125:.
1060:.
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590:.
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