223:
776:
51:
579:
526:
receptors, suggesting a role for dopamine in schizophrenia. Additional studies hypothesize dopamine dysregulation is involved in
Huntington's disease, ADHD, Tourette's syndrome, major depression, manic depression, addiction, hypertension and kidney dysfunction. Dopamine receptor antagonists are used
726:
First generation antipsychotics are used to treat schizophrenia and are often accompanied by extrapyramidal side effects. They inhibit dopaminergic neurotransmission in the brain by blocking about 72% of the D2 dopamine receptors. They can also block noradrenergic, cholinergic, and histaminergic
1215:
receptor and is used to treat schizophrenia, depression and bipolar disorder. There is controversy on whether
Ziprasidone treats negative symptoms and it has well documented gastrointestinal side effects. Ziprasidone can also cause
1065:. Clozapine is unique because it is only prescribed when treatment with at least two other antipsychotics has failed due to its very harsh side effects. It also requires weekly white blood cell counts to monitor potential
1136:
at high concentrations. It is used to treat the positive symptoms of schizophrenia, bipolar disorder and depression. Of the second generation antipsychotics, quetiapine may produce fewer parkinsonian side
1748:
Willis GL (2008). "Parkinson's disease as a neuroendocrine disorder of circadian function: dopamine-melatonin imbalance and the visual system in the genesis and progression of the degenerative process".
488:
are highly expressed on neurons in islands of
Calleja and nucleus accumbens shell and lowly expressed in areas such as the substantia nigra pars compacta, hippocampus, septal area, and ventral tegmental
522:
The dopaminergic system has been implicated in a variety of disorders. Parkinson's disease results from loss of dopaminergic neurons in the striatum. Furthermore, most effective antipsychotics block D
5760:
1114:
binds all receptors and is used to treat the positive and negative symptoms of schizophrenia as well as bipolar disorder and depression. It has been associated with significant weight gain.
1516:
Sokoloff P, Diaz J, Le Foll B, Guillin O, Leriche L, Bezard E, Gross C (February 2006). "The dopamine D3 receptor: a therapeutic target for the treatment of neuropsychiatric disorders".
2154:
1038:
5753:
1019:
and is used to treat bipolar disorder and schizophrenia. Its side effects include weight gain but there is lower risk for orthostatic hypotension and hyperprolactinemia.
3731:
5746:
441:-like class, these receptors are found pre and post-synaptically. The genes that code these receptors have introns, leading to many alternately spliced variants.
467:
Peripherally, these receptors have been found in the renal, mesenteric, and splenic arteries as well as on the adrenal cortex and medulla and within the kidney.
3003:
349:
Peripherally, these receptors have been found in the renal artery, mesenteric artery, and splenic artery where activation leads to vasodilation. In addition, D
95:
1803:
Young SL, Taylor M, Lawrie SM (April 2015). ""First do no harm." A systematic review of the prevalence and management of antipsychotic adverse effects".
1205:
and is used as an antipsychotic. It is also often used to treat dyskinesias, psychomotor agitations, tics, Huntington's chorea and alcohol dependence.
2882:
Alsalmi M, Al-Kassmy J, Kang W, Palayew M, Huot P (2024). "Levodopa-induced dyskinesia: do current clinical trials hold hope for future treatment?".
1001:
and is used as an antipsychotic, antidepressant and also treats bipolar disorder. It treats both the positive and negative symptoms of schizophrenia.
4827:
3254:
4208:
3475:
461:
are found in the striatum, substantia nigra, ventral tegmental area, hypothalamus, cortex, septum, amygdala, hippocampus, and olfactory tubercle.
4902:
4797:
4158:
3541:
4767:
4594:
3505:
3399:
2760:"A review of the discovery, pharmacological characterization, and behavioral effects of the dopamine D2-like receptor antagonist eticlopride"
6310:
5058:
4444:
4403:
4353:
4298:
3289:
3269:
3086:
2419:
986:
These drugs have fewer extrapyramidal side effects and are less likely to affect prolactin levels when compared to typical antipsychotics.
2517:
Pollack CV (July 2016). "Inhaled loxapine for the urgent treatment of acute agitation associated with schizophrenia or bipolar disorder".
513:
are found in amygdala, hippocampus, hypothalamus, globus pallidus, substantia nigra pars reticula, the thalamus, the retina and the kidney
3531:
1091:
Loxapine is often used to treat agitated and violent patients with neuropsychiatric disorders such as bipolar disorder and schizophrenia.
2690:
Stahl SM, Shayegan DK (2003). "The psychopharmacology of ziprasidone: receptor-binding properties and real-world psychiatric practice".
4847:
3551:
3112:
2996:
3179:
2719:"Review article: clinical implications of enteric and central D2 receptor blockade by antidopaminergic gastrointestinal prokinetics"
5512:
5014:
4922:
4978:
4996:
4987:
3329:
3324:
2989:
1191:
receptors. Risperidone not only treats the positive and negative symptoms of schizophrenia but also treats bipolar disorder.
5785:
5770:
2647:
Dose M, Lange HW (January 2000). "The benzamide tiapride: treatment of extrapyramidal motor and other clinical syndromes".
1233:
is a peripherally selective dopamine D2 receptor antagonist used as an antiemetic, gastroprokinetic agent and galactagogue.
6093:
5005:
599:– muscle spasms and sustained abnormal postures and onset occurs within a few days; can be treated with anticholinergics
5665:
5609:
5318:
1584:
Missale C, Nash SR, Robinson SW, Jaber M, Caron MG (January 1998). "Dopamine receptors: from structure to function".
284:
are always found post-synaptically. The genes coding these receptors lack introns, so there are no splice variants.
5502:
5051:
5684:
5598:
4387:
3418:
592:
Early stage – occurs at onset of treatment or following increased dose, patients recover when dose is decreased
5670:
5023:
2561:
1705:
Zisapel N (December 2001). "Melatonin-dopamine interactions: from basic neurochemistry to a clinical setting".
1436:
Beaulieu JM, Gainetdinov RR (March 2011). "The physiology, signaling, and pharmacology of dopamine receptors".
701:
231:
6336:
5492:
5146:
5140:
633:
Late stage – occurs after prolonged (months-years) treatment, symptoms persist even after dose is decreased
6153:
5659:
5431:
4969:
2006:
1217:
966:
819:
5981:
5574:
5347:
5044:
1315:
20:
5738:
6283:
6045:
5413:
5252:
5239:
5210:
5155:
4292:
3393:
2919:"Neuronal Dopamine D3 Receptors: Translational Implications for Preclinical Research and CNS Disorders"
1301:
and can be radiolabeled and used in PET imaging to identify disease progression in
Huntington's Disease
1033:
In addition, aripiprazole treats schizophrenia, bipolar disorder (mania), depression, and tic disorders
6213:
5709:
5226:
2369:"Aripiprazole for the treatment of tic disorders in children: a systematic review and meta-analysis"
2278:
Stoner SC, Pace HA (May 2012). "Asenapine: a clinical review of a second-generation antipsychotic".
5603:
5549:
5534:
5506:
5287:
5282:
5273:
2975:
2917:
Kiss B, Laszlovszky I, Krámos B, Visegrády A, Bobok A, Lévay G, Lendvai B, Román V (January 2021).
691:
124:
5887:
5704:
5675:
5643:
5473:
5278:
5234:
5185:
5116:
3811:
623:
due to effects on the nigrostriatal pathway - includes tremors, bradykinesia and muscle rigidity
586:
2971:
566:
They may include one or more of the following and last indefinitely even after cessation of the
5897:
5585:
5391:
4197:
3373:
1323:
574:
555:
6203:
6174:
5798:
5716:
5560:
5293:
5180:
4543:
3817:
3484:
59:
610:- pacing and restlessness and onset occurs within the first few months; can be treated with
5927:
5721:
5565:
5418:
5371:
4792:
4003:
3274:
1953:"Pharmacology of the atypical antipsychotic remoxipride, a dopamine D2 receptor antagonist"
506:
481:
454:
368:
297:
8:
6220:
5865:
5130:
4932:
3665:
3304:
3107:
978:
These drugs are not only dopamine antagonists at the receptor specified, but also act on
658:
192:
176:
168:
2443:
6128:
5962:
5569:
5538:
5269:
5165:
3015:
2945:
2918:
2833:
2808:
2784:
2759:
2672:
2624:
2599:
2542:
2494:
2467:
2395:
2368:
2341:
2314:
2209:
2184:
2125:
2100:
1977:
1968:
1952:
1923:
1896:
1828:
1774:
1730:
1687:
1644:
1461:
681:
636:
172:
234:, and are divided into two classes based on which G-protein they are coupled to. The D
6225:
6167:
5947:
5922:
5638:
5543:
5366:
5159:
4862:
4720:
3012:
2950:
2899:
2838:
2789:
2775:
2740:
2735:
2718:
2699:
2676:
2664:
2629:
2577:
2534:
2499:
2448:
2400:
2346:
2295:
2260:
2214:
2162:
2130:
2078:
2026:
1982:
1928:
1860:
1820:
1766:
1762:
1722:
1679:
1636:
1601:
1533:
1453:
743:
396:
380:
305:
112:
107:
2291:
1778:
1734:
1691:
1648:
6208:
6083:
6022:
5957:
5840:
5628:
5422:
5337:
5091:
4842:
4710:
4318:
4133:
3742:
3575:
3184:
3023:
2940:
2930:
2891:
2856:
2828:
2820:
2779:
2771:
2730:
2717:
Tonini M, Cipollina L, Poluzzi E, Crema F, Corazza GR, De Ponti F (February 2004).
2656:
2619:
2611:
2573:
2569:
2546:
2526:
2489:
2479:
2438:
2434:
2430:
2390:
2380:
2336:
2326:
2287:
2250:
2204:
2200:
2196:
2120:
2112:
2068:
2018:
1972:
1964:
1918:
1908:
1832:
1812:
1758:
1714:
1671:
1628:
1593:
1525:
1465:
1445:
551:
532:
430:
384:
309:
273:
243:
188:
79:
55:
24:
2895:
2530:
2007:"Effects of antipsychotic medications on appetite, weight, and insulin resistance"
1597:
6118:
5556:
5468:
5306:
5301:
5171:
5135:
5125:
5108:
4393:
4383:
4363:
4233:
4143:
3414:
3364:
2061:"How do we choose between atypical antipsychotics? The advantages of amisulpride"
1851:
Arana GW (2000). "An overview of side effects caused by typical antipsychotics".
130:
6275:
6230:
6123:
5248:
5103:
5086:
4695:
4670:
4635:
4559:
4408:
4138:
4098:
3424:
3359:
2981:
2255:
2238:
1675:
1619:
Seeman P (August 2006). "Targeting the dopamine D2 receptor in schizophrenia".
1529:
1250:
749:
615:
325:
180:
2824:
2615:
2484:
2385:
2073:
2060:
2022:
1718:
1632:
222:
6330:
6113:
6013:
5967:
5952:
5917:
5892:
5820:
5484:
5383:
5375:
5358:
5297:
4907:
4822:
4782:
4655:
4474:
4398:
4358:
4338:
4238:
3983:
3832:
3827:
3770:
3721:
3650:
3455:
3217:
3153:
2116:
1816:
1244:
528:
392:
184:
100:
75:
6088:
5907:
5845:
5830:
5774:
5463:
5329:
5312:
5067:
4917:
4912:
4897:
4817:
4777:
4751:
4746:
4705:
4700:
4549:
4494:
4484:
4449:
4439:
4368:
4328:
4288:
4248:
4223:
4213:
4203:
4153:
4128:
4123:
4093:
4048:
3852:
3847:
3807:
3660:
3490:
3470:
3460:
3404:
3389:
3379:
3294:
2954:
2903:
2842:
2793:
2744:
2703:
2668:
2633:
2581:
2538:
2503:
2452:
2404:
2350:
2299:
2264:
2218:
2166:
2134:
2082:
2030:
1986:
1932:
1864:
1824:
1770:
1726:
1683:
1640:
1537:
1457:
1140:
1022:
942:
884:
869:
825:
784:
705:
620:
611:
376:
332:
321:
1913:
1605:
1449:
665:
receptors in the anterior pituitary leading to increased prolactin release
649:
It is hypothesized that these effects are due to chronic blockade of the D
6293:
6270:
6191:
6148:
6143:
6108:
6037:
5991:
5937:
5932:
5912:
5902:
5855:
5768:
5620:
5593:
5526:
5219:
5099:
4882:
4867:
4852:
4715:
4685:
4680:
4675:
4645:
4619:
4614:
4609:
4584:
4579:
4564:
4554:
4534:
4529:
4514:
4504:
4499:
4489:
4469:
4454:
4434:
4419:
4373:
4308:
4283:
4273:
4268:
4263:
4218:
4193:
4163:
4113:
4073:
4018:
4013:
3993:
3958:
3943:
3933:
3923:
3903:
3893:
3837:
3752:
3675:
3670:
3655:
3608:
3515:
3510:
3500:
3465:
3440:
3409:
3369:
3249:
3194:
3168:
3158:
3097:
2935:
1277:
1263:
1230:
1224:
1208:
1176:
1166:
1094:
1066:
990:
965:
at higher concentrations
Thioridazine has the highest associated risk of
874:
847:
795:
388:
344:
203:
2660:
1662:
Iversen SD, Iversen LL (May 2007). "Dopamine: 50 years in perspective".
492:
Additional studies have found these receptors peripherally in the kidney
143:
6305:
6265:
6260:
6255:
6240:
6138:
6103:
6098:
6078:
6001:
5996:
5850:
5835:
5825:
5446:
5261:
4887:
4877:
4872:
4857:
4812:
4807:
4736:
4665:
4660:
4650:
4604:
4599:
4589:
4574:
4569:
4539:
4509:
4479:
4459:
4378:
4348:
4188:
4183:
4178:
4173:
4168:
4148:
4118:
4108:
4068:
4063:
4058:
4053:
4038:
4023:
3978:
3973:
3968:
3963:
3928:
3918:
3913:
3898:
3822:
3786:
3747:
3726:
3680:
3634:
3598:
3546:
3495:
3480:
3445:
3354:
3284:
3279:
3264:
3259:
3212:
3189:
3163:
3148:
3102:
3076:
3071:
3066:
3061:
3056:
3051:
2331:
1311:
1290:
1236:
1117:
1111:
789:
731:
668:
464:
These receptors have also been found in the retina and pituitary gland.
340:
199:
41:
183:
are dopamine antagonists, and as such they have found use in treating
6315:
6298:
6133:
6055:
6032:
5877:
5815:
5455:
5405:
5036:
4947:
4927:
4892:
4837:
4832:
4787:
4741:
4731:
4524:
4519:
4464:
4424:
4343:
4333:
4323:
4313:
4228:
4103:
4043:
4033:
4008:
3998:
3988:
3948:
3888:
3883:
3802:
3757:
3700:
3695:
3629:
3624:
3619:
3603:
3561:
3556:
3450:
3435:
3334:
3299:
3199:
3127:
3122:
2239:"QTc prolongation, torsades de pointes, and psychotropic medications"
1897:"Second-generation antipsychotics and extrapyramidal adverse effects"
1319:
1046:
1004:
979:
928:
907:
739:
671:
including increased craving and binge eating that lead to weight gain
607:
547:
554:
functions, although pathological imbalances have been implicated in
6186:
6073:
5882:
5496:
4937:
4772:
4690:
4624:
4303:
4278:
4253:
4243:
3953:
3938:
3868:
3778:
3716:
3711:
3685:
3536:
3520:
3384:
3225:
3117:
3081:
3046:
2562:"Quetiapine versus other atypical antipsychotics for schizophrenia"
1194:
1072:
889:
879:
696:
596:
567:
540:
336:
317:
313:
211:
196:
87:
2312:
5942:
5120:
4802:
4640:
4429:
4258:
4028:
3878:
3873:
3842:
3791:
3244:
3233:
3143:
3138:
775:
687:
675:
578:
5633:
5202:
5082:
4942:
3908:
3762:
3639:
3204:
2313:
Scheidemantel T, Korobkova I, Rej S, Sajatovic M (2015-12-04).
1894:
536:
207:
83:
2916:
973:
50:
4762:
3863:
1257:
1037:
721:
2881:
2716:
570:
antagonist, especially after long-term or high-dosage use:
2813:
European
Journal of Nuclear Medicine and Molecular Imaging
2600:"Comparative Pharmacology of Risperidone and Paliperidone"
1515:
779:
Chemical
Structure of typical antipsychotic chlorpromazine
3690:
2910:
2875:
1583:
2809:"Current status of PET imaging in Huntington's disease"
2367:
Yang CS, Huang H, Zhang LL, Zhu CR, Guo Q (July 2015).
639:- includes involuntary and repetitive facial movements
2849:
2806:
2593:
2591:
2420:"Aripiprazole alone or in combination for acute mania"
1895:
Divac N, Prostran M, Jakovcevski I, Cerovac N (2014).
1225:
Dopamine antagonists used to treat nausea and vomiting
2011:
Endocrinology and
Metabolism Clinics of North America
742:
receptors. It is absorbed very easily and has a high
2065:
2588:
1435:
602:
risk factors include age, gender and family history
410:
238:-like class of dopamine receptors is coupled to Gα
2417:
2366:
2054:
2052:
2050:
2048:
2046:
2044:
2042:
2040:
1802:
1511:
1509:
1507:
1505:
1503:
1501:
1499:
1497:
1495:
1431:
1429:
1427:
1425:
1423:
1421:
1419:
1417:
1415:
1413:
1411:
1409:
1407:
1405:
1403:
1401:
1399:
1397:
1395:
1393:
1391:
1389:
1387:
1385:
1383:
1381:
1379:
1377:
1375:
1373:
1371:
1369:
1367:
1365:
1363:
1361:
1359:
6328:
3011:
2857:"Mesdopetam - Integrative Research Laboratories"
2465:
1579:
1577:
1575:
1573:
1571:
1569:
1567:
1493:
1491:
1489:
1487:
1485:
1483:
1481:
1479:
1477:
1475:
1357:
1355:
1353:
1351:
1349:
1347:
1345:
1343:
1341:
1339:
254:and thus inhibits adenylate cyclase production.
1565:
1563:
1561:
1559:
1557:
1555:
1553:
1551:
1549:
1547:
704:is a medical emergency caused by a decrease in
550:suppresses dopamine activity as part of normal
257:
2807:Pagano G, Niccolini F, Politis M (June 2016).
2418:Brown R, Taylor MJ, Geddes J (December 2013).
2178:
2176:
2037:
1946:
1944:
1942:
1661:
589:(EPS) associated with typical antipsychotics:
5754:
5052:
2997:
2757:
2689:
2597:
2182:
1890:
1888:
1886:
1884:
1882:
1880:
1878:
1876:
1874:
1518:CNS & Neurological Disorders Drug Targets
1472:
1336:
1305:
3743:Deoxyepinephrine (N-methyldopamine, epinine)
3185:Deoxyepinephrine (N-methyldopamine, epinine)
2362:
2360:
1846:
1844:
1842:
1798:
1796:
1794:
1792:
1790:
1788:
1544:
2427:The Cochrane Database of Systematic Reviews
2189:The Cochrane Database of Systematic Reviews
2173:
2000:
1998:
1996:
1939:
1057:with the highest affinity but still binds D
974:Second-generation antipsychotics (atypical)
810:with the highest affinity, but also binds D
792:is used as an antipsychotic and antiemetic.
756:with the highest affinity, but also binds D
5761:
5747:
5059:
5045:
3004:
2990:
2723:Alimentary Pharmacology & Therapeutics
2468:"Revisiting loxapine: a systematic review"
2277:
2152:
1871:
1258:Antagonists used only in research settings
517:
49:
5260:
2974:at the U.S. National Library of Medicine
2944:
2934:
2832:
2783:
2734:
2646:
2623:
2493:
2483:
2466:Popovic D, Nuss P, Vieta E (2015-04-01).
2442:
2394:
2384:
2357:
2340:
2330:
2254:
2208:
2124:
2072:
1976:
1922:
1912:
1839:
1785:
722:First-generation antipsychotics (typical)
686:Metabolic changes with increased risk of
642:risk factors include age, race and gender
2058:
1993:
1036:
774:
577:
221:
217:
4632:Antiemetics/gastroprokinetics/sedatives
2566:Cochrane Database of Systematic Reviews
2516:
1704:
1173:receptors with relatively low affinity.
406:receptors have been found in the kidney
353:receptors have been found in the kidney
6329:
5066:
2319:Neuropsychiatric Disease and Treatment
2153:Chokhawala, Krutika (2 October 2021).
2098:
1747:
1618:
1029:as a partial agonist but antagonizes D
939:and is also used as an antidepressant.
866:and is also used as an antidepressant.
5771:functional gastrointestinal disorders
5742:
5040:
2985:
2559:
2243:The Academy of Psychosomatic Medicine
2236:
2232:
2230:
2228:
2148:
2146:
2144:
2094:
2092:
1950:
1850:
1621:Expert Opinion on Therapeutic Targets
2519:Current Medical Research and Opinion
2004:
1274:with high affinity but also binds D4
331:Also found (in lower levels) in the
16:Drug which blocks dopamine receptors
6094:Dimethylaminopropionylphenothiazine
4234:Levomepromazine (methotrimeprazine)
2764:CNS Neuroscience & Therapeutics
1707:Cellular and Molecular Neurobiology
1155:with high affinity; can also bind D
1087:with high affinity; can also bind D
957:with high affinity; can also bind D
922:with high affinity; can also bind D
626:risk factors include age and gender
304:are found mainly on neurons in the
13:
5666:Angiotensin II receptor antagonist
5610:Endocannabinoid reuptake inhibitor
2692:The Journal of Clinical Psychiatry
2225:
2183:Leucht S, Hartung B (April 2005).
2141:
2089:
1969:10.1111/j.1527-3458.2001.tb00199.x
1859:(Suppl 8): 5–11, discussion 12–3.
1853:The Journal of Clinical Psychiatry
708:activity, resulting in a central D
387:; as well as memory areas such as
14:
6348:
5557:Acetylcholine receptor antagonist
5319:Norepinephrine reuptake inhibitor
2965:
2776:10.1111/j.1755-5949.2008.00047.x
2736:10.1111/j.1365-2036.2004.01867.x
2315:"Asenapine for bipolar disorder"
2101:"Neuroleptic Malignant Syndrome"
1763:10.1515/revneuro.2008.19.4-5.245
900:with high affinity, also binds D
818:Haloperidol also has a risk for
5685:Vasopressin receptor antagonist
5599:Cannabinoid receptor antagonist
5015:Monoamine metabolism modulators
2800:
2751:
2710:
2683:
2640:
2553:
2510:
2459:
2411:
2306:
2292:10.1016/j.clinthera.2012.03.002
2271:
836:with the highest affinity but D
561:
496:
471:
444:
357:
287:
6250:Primarily dopamine antagonists
6199:Quaternary ammonium compounds:
5671:Endothelin receptor antagonist
5535:Acetylcholine receptor agonist
5294:Adrenergic receptor antagonist
2758:Martelle JL, Nader MA (2008).
2574:10.1002/14651858.CD006625.pub3
2435:10.1002/14651858.CD005000.pub2
2201:10.1002/14651858.CD003083.pub2
2185:"Benperidol for schizophrenia"
2099:Berman, Brian (January 2011).
1741:
1698:
1655:
1612:
702:Neuroleptic Malignant Syndrome
1:
5503:Glutamate receptor antagonist
5419:Serotonin receptor antagonist
5372:Histamine receptor antagonist
5147:Negative allosteric modulator
5141:Positive allosteric modulator
4997:Monoamine reuptake inhibitors
4970:Receptor/signaling modulators
3149:Adrogolide (ABT-431, DAS-431)
2896:10.1080/14656566.2023.2298345
2598:Corena-McLeod M (June 2015).
2531:10.1185/03007995.2016.1170004
1901:BioMed Research International
1805:Journal of Psychopharmacology
1598:10.1152/physrev.1998.78.1.189
1329:
6154:Trimethyldiphenylpropylamine
5660:Adenosine reuptake inhibitor
5594:Cannabinoid receptor agonist
5513:Glutamate reuptake inhibitor
5432:Serotonin reuptake inhibitor
5343:Dopamine receptor antagonist
2472:Annals of General Psychiatry
1751:Reviews in the Neurosciences
250:-like class is coupled to Gα
226:Dopamine receptor flow chart
161:dopamine receptor antagonist
33:Dopamine receptor antagonist
7:
5348:Dopamine reuptake inhibitor
5270:Adrenergic receptor agonist
2155:"Antipsychotic Medications"
1316:levodopa-induced dyskinesia
716:
232:G protein–coupled receptors
230:Dopamine receptors are all
56:Skeletal structural formula
21:dopamine reuptake inhibitor
10:
6353:
5639:Opioid receptor antagonist
5493:Glutamate receptor agonist
5414:Serotonin receptor agonist
5367:Histamine receptor agonist
5006:Monoamine releasing agents
4194:Flupentixol (flupenthixol)
3370:Flupentixol (flupenthixol)
2256:10.1016/j.psym.2012.11.001
2059:Mortimer AM (March 2004).
1676:10.1016/j.tins.2007.03.002
1530:10.2174/187152706784111551
1306:Other dopamine antagonists
1243:receptors and also treats
527:for some diseases such as
18:
6239:
6166:
6066:
6010:
5980:
5864:
5806:
5797:
5782:
5697:
5652:
5619:
5584:
5525:
5483:
5454:
5445:
5404:
5357:
5338:Dopamine receptor agonist
5328:
5247:
5233:
5218:
5201:
5194:
5074:
4960:
4858:Metitepine (methiothepin)
4284:Pericyazine (periciazine)
4082:
3708:Dihydrexidine derivatives
3587:
3574:
3547:Metitepine (methiothepin)
3343:
3313:
3135:Dihydrexidine derivatives
3035:
3022:
2825:10.1007/s00259-016-3324-6
2616:10.1007/s40268-015-0092-x
2485:10.1186/s12991-015-0053-3
2386:10.1186/s12888-015-0504-z
2074:10.1017/S1461145704004134
2023:10.1016/j.ecl.2013.05.006
2005:Deng C (September 2013).
1633:10.1517/14728222.10.4.515
1314:is under development for
1253:also treats gastroparesis
246:production, whereas the D
206:used in the treatment of
142:
137:
123:
118:
106:
94:
71:
66:
48:
39:
32:
5604:Endocannabinoid enhancer
5550:Cholinesterase inhibitor
5469:GABA receptor antagonist
4460:Clotiapine (clothiapine)
4334:Spiperone (spiroperidol)
4299:Piflutixol (pifluthixol)
2976:Medical Subject Headings
2884:Expert Opin Pharmacother
2117:10.1177/1941875210386491
2067:. 7 Suppl 1 (5): S21-5.
1817:10.1177/0269881114562090
692:diabetes mellitus type 2
661:due to blockade of the D
19:Not to be confused with
5644:Enkephalinase inhibitor
5634:Opioid receptor agonist
5474:GABA reuptake inhibitor
5179:♦ Miscellaneous:
4416:Atypical antipsychotics
3799:Atypical antipsychotics
3732:N,N-Propyldihydrexidine
3432:Atypical antipsychotics
3321:Tetrahydroisoquinolines
1719:10.1023/A:1015187601628
1664:Trends in Neurosciences
1438:Pharmacological Reviews
587:Extrapyramidal symptoms
518:Implications in disease
375:have been found in the
5227:Ion channel modulators
4090:Typical antipsychotics
3351:Typical antipsychotics
2105:The Neuro Hospitalists
1042:
780:
582:
575:Cardiovascular disease
227:
5464:GABA receptor agonist
5024:Monoamine neurotoxins
3818:Aripiprazole lauroxil
2560:Asmal, Laila (2013).
2280:Clinical Therapeutics
2237:Beach, Scott (2013).
1586:Physiological Reviews
1450:10.1124/pr.110.002642
1040:
778:
581:
225:
218:Receptor pharmacology
60:typical antipsychotic
35:Dopaminergic blockers
6337:Dopamine antagonists
4793:Desmethoxyfallypride
4004:Propylnorapomorphine
3803:Alentemol (U-66444B)
3275:Propylnorapomorphine
2972:Dopamine+antagonists
2936:10.3390/biom11010104
6221:Cimetropium bromide
6014:serotonin receptors
5680:receptor antagonist
4933:Tetrahydropalmatine
3666:Dihydroergocryptine
3305:Tetrahydropalmatine
3108:Dihydroergocryptine
2661:10.1055/s-2000-7964
1914:10.1155/2014/656370
1324:Parkinson's disease
969:among neuroleptics.
674:Increased risk for
659:Hyperprolactinaemia
556:Parkinson's disease
193:stimulant psychosis
177:receptor antagonism
155:, also known as an
153:dopamine antagonist
6129:Pinaverium bromide
5068:Pharmacomodulation
2863:. 6 September 2024
2698:(Suppl 19): 6–12.
2649:Pharmacopsychiatry
2332:10.2147/NDT.S78043
1043:
781:
712:receptor blockade.
682:Sexual dysfunction
669:Increased appetite
637:Tardive dyskinesia
583:
415:-like receptors: D
262:-like receptors: D
228:
173:dopamine receptors
113:Dopamine receptors
58:of Haloperidol, a
6324:
6323:
6226:Fentonium bromide
6214:Methylscopolamine
6162:
6161:
5982:Phosphodiesterase
5976:
5975:
5736:
5735:
5732:
5731:
5693:
5692:
5521:
5520:
5441:
5440:
5211:Enzyme inhibition
5034:
5033:
5027:
5018:
5009:
5000:
4991:
4982:
4973:
4956:
4955:
4863:N-Methylspiperone
4721:Trimethobenzamide
3781:
3773:
3765:
3570:
3569:
3228:
3220:
3207:
3013:Dopamine receptor
2169:– via NCBI.
744:first pass effect
397:entorhinal cortex
381:prefrontal cortex
306:nucleus accumbens
274:D1-like receptors
244:adenylate cyclase
157:anti-dopaminergic
149:
148:
108:Biological target
67:Class identifiers
6344:
6209:Butylscopolamine
6184:Tertiary amines:
6084:Chlorbenzoxamine
5841:Oxyphencyclimine
5804:
5803:
5795:
5794:
5763:
5756:
5749:
5740:
5739:
5710:Enzyme cofactors
5629:Opioid modulator
5586:Cannabinoidergic
5452:
5451:
5258:
5257:
5245:
5244:
5199:
5198:
5061:
5054:
5047:
5038:
5037:
5021:
5012:
5003:
4994:
4985:
4976:
4964:
4843:Levofenfluramine
4711:Thiethylperazine
4388:+tranylcypromine
4319:Prochlorperazine
4134:Chlorproethazine
3779:
3771:
3766:-DOPA (levodopa)
3763:
3585:
3584:
3419:+tranylcypromine
3226:
3218:
3208:-DOPA (levodopa)
3205:
3033:
3032:
3006:
2999:
2992:
2983:
2982:
2959:
2958:
2948:
2938:
2914:
2908:
2907:
2879:
2873:
2872:
2870:
2868:
2853:
2847:
2846:
2836:
2804:
2798:
2797:
2787:
2755:
2749:
2748:
2738:
2714:
2708:
2707:
2687:
2681:
2680:
2644:
2638:
2637:
2627:
2604:Drugs in R&D
2595:
2586:
2585:
2568:(11): CD006625.
2557:
2551:
2550:
2514:
2508:
2507:
2497:
2487:
2463:
2457:
2456:
2446:
2429:(12): CD005000.
2424:
2415:
2409:
2408:
2398:
2388:
2364:
2355:
2354:
2344:
2334:
2310:
2304:
2303:
2275:
2269:
2268:
2258:
2234:
2223:
2222:
2212:
2180:
2171:
2170:
2150:
2139:
2138:
2128:
2096:
2087:
2086:
2076:
2056:
2035:
2034:
2002:
1991:
1990:
1980:
1957:CNS Drug Reviews
1951:Nadal R (2001).
1948:
1937:
1936:
1926:
1916:
1892:
1869:
1868:
1848:
1837:
1836:
1800:
1783:
1782:
1757:(4–5): 245–316.
1745:
1739:
1738:
1702:
1696:
1695:
1659:
1653:
1652:
1616:
1610:
1609:
1581:
1542:
1541:
1513:
1470:
1469:
1433:
1218:QTc prolongation
967:QTc prolongation
820:QTc prolongation
552:circadian rhythm
533:bipolar disorder
385:cingulate cortex
310:substantia nigra
195:. Several other
189:bipolar disorder
167:), is a type of
133:
80:bipolar disorder
53:
30:
29:
25:dopamine agonist
6352:
6351:
6347:
6346:
6345:
6343:
6342:
6341:
6327:
6326:
6325:
6320:
6287:
6235:
6175:antimuscarinics
6172:
6171:and derivatives
6170:
6158:
6119:Mentha piperita
6062:
6049:
6026:
6012:
6006:
5983:
5972:
5870:
5867:
5860:
5808:
5799:Antimuscarinics
5789:
5787:
5784:
5778:
5767:
5737:
5728:
5689:
5679:
5648:
5615:
5580:
5517:
5479:
5437:
5426:
5400:
5395:
5387:
5379:
5353:
5324:
5238:
5229:
5214:
5190:
5136:Inverse agonist
5126:Partial agonist
5070:
5065:
5035:
5030:
4952:
4728:Antidepressants
4394:Triflupromazine
4384:Trifluoperazine
4364:Thioproperazine
4144:Chlorprothixene
4078:
3739:Phenethylamines
3579:
3566:
3415:Trifluoperazine
3365:Chlorprothixene
3339:
3309:
3176:Phenethylamines
3027:
3018:
3010:
2968:
2963:
2962:
2915:
2911:
2880:
2876:
2866:
2864:
2855:
2854:
2850:
2805:
2801:
2756:
2752:
2715:
2711:
2688:
2684:
2645:
2641:
2596:
2589:
2558:
2554:
2515:
2511:
2464:
2460:
2422:
2416:
2412:
2365:
2358:
2311:
2307:
2276:
2272:
2235:
2226:
2195:(2): CD003083.
2181:
2174:
2151:
2142:
2097:
2090:
2057:
2038:
2003:
1994:
1949:
1940:
1893:
1872:
1849:
1840:
1801:
1786:
1746:
1742:
1703:
1699:
1660:
1656:
1617:
1613:
1582:
1545:
1514:
1473:
1434:
1337:
1332:
1322:in people with
1308:
1300:
1296:
1287:
1283:
1273:
1269:
1260:
1242:
1239:binds enteric D
1227:
1214:
1204:
1200:
1190:
1186:
1182:
1172:
1162:
1158:
1154:
1150:
1146:
1135:
1131:
1127:
1123:
1108:
1104:
1100:
1090:
1086:
1082:
1078:
1064:
1060:
1056:
1052:
1032:
1028:
1018:
1014:
1010:
1000:
996:
985:
976:
964:
960:
956:
952:
948:
938:
934:
925:
921:
917:
913:
903:
899:
895:
865:
861:
857:
853:
843:
839:
835:
831:
817:
813:
809:
805:
801:
771:
767:
763:
759:
755:
737:
724:
719:
711:
664:
652:
616:benzodiazepines
564:
525:
520:
510:
503:
500:
485:
478:
475:
458:
451:
448:
440:
435:-like receptors
434:
428:
426:
422:
418:
414:
405:
372:
364:
361:
352:
301:
294:
291:
283:
279:
271:
269:
265:
261:
253:
249:
242:and stimulates
241:
237:
220:
129:
62:
34:
28:
17:
12:
11:
5:
6350:
6340:
6339:
6322:
6321:
6319:
6318:
6313:
6308:
6303:
6302:
6301:
6296:
6285:
6280:
6279:
6278:
6276:Metoclopramide
6273:
6268:
6263:
6258:
6245:
6243:
6237:
6236:
6234:
6233:
6231:Methylatropine
6228:
6223:
6218:
6217:
6216:
6211:
6206:
6195:
6194:
6189:
6180:
6178:
6164:
6163:
6160:
6159:
6157:
6156:
6151:
6146:
6141:
6136:
6131:
6126:
6124:Phloroglucinol
6121:
6116:
6111:
6106:
6101:
6096:
6091:
6086:
6081:
6076:
6070:
6068:
6064:
6063:
6061:
6060:
6059:
6058:
6047:
6042:
6041:
6040:
6035:
6024:
6018:
6016:
6008:
6007:
6005:
6004:
5999:
5994:
5988:
5986:
5978:
5977:
5974:
5973:
5971:
5970:
5965:
5960:
5955:
5950:
5945:
5940:
5935:
5930:
5925:
5920:
5915:
5910:
5905:
5900:
5898:Glycopyrronium
5895:
5890:
5885:
5880:
5874:
5872:
5862:
5861:
5859:
5858:
5853:
5848:
5843:
5838:
5833:
5828:
5823:
5818:
5812:
5810:
5801:
5792:
5780:
5779:
5766:
5765:
5758:
5751:
5743:
5734:
5733:
5730:
5729:
5727:
5726:
5714:
5701:
5699:
5695:
5694:
5691:
5690:
5688:
5687:
5682:
5677:
5673:
5668:
5663:
5656:
5654:
5650:
5649:
5647:
5646:
5641:
5636:
5631:
5625:
5623:
5617:
5616:
5614:
5613:
5607:
5601:
5596:
5590:
5588:
5582:
5581:
5579:
5578:
5572:
5563:
5554:
5553:
5552:
5541:
5531:
5529:
5523:
5522:
5519:
5518:
5516:
5515:
5510:
5500:
5489:
5487:
5481:
5480:
5478:
5477:
5471:
5466:
5460:
5458:
5449:
5443:
5442:
5439:
5438:
5436:
5435:
5429:
5424:
5416:
5410:
5408:
5402:
5401:
5399:
5398:
5393:
5389:
5385:
5381:
5377:
5369:
5363:
5361:
5355:
5354:
5352:
5351:
5345:
5340:
5334:
5332:
5326:
5325:
5323:
5322:
5316:
5310:
5304:
5291:
5285:
5276:
5266:
5264:
5255:
5242:
5231:
5230:
5224:
5222:
5216:
5215:
5207:
5205:
5196:
5192:
5191:
5189:
5188:
5183:
5176:
5175:
5169:
5163:
5151:
5150:
5144:
5138:
5133:
5128:
5123:
5112:
5111:
5106:
5095:
5094:
5089:
5078:
5076:
5072:
5071:
5064:
5063:
5056:
5049:
5041:
5032:
5031:
5029:
5028:
5019:
5010:
5001:
4992:
4983:
4974:
4961:
4958:
4957:
4954:
4953:
4951:
4950:
4945:
4940:
4935:
4930:
4925:
4920:
4915:
4910:
4905:
4900:
4895:
4890:
4885:
4880:
4875:
4870:
4865:
4860:
4855:
4850:
4845:
4840:
4835:
4830:
4828:Isocorypalmine
4825:
4820:
4815:
4810:
4805:
4800:
4795:
4790:
4785:
4780:
4775:
4770:
4765:
4755:
4754:
4749:
4744:
4739:
4734:
4724:
4723:
4718:
4713:
4708:
4703:
4698:
4696:Metoclopramide
4693:
4688:
4683:
4678:
4673:
4671:Deudomperidone
4668:
4663:
4658:
4653:
4648:
4643:
4638:
4636:Aceprometazine
4628:
4627:
4622:
4617:
4612:
4607:
4602:
4597:
4592:
4587:
4582:
4577:
4572:
4567:
4562:
4560:Piperacetazine
4557:
4552:
4547:
4537:
4532:
4527:
4522:
4517:
4512:
4507:
4502:
4497:
4492:
4487:
4482:
4477:
4472:
4467:
4462:
4457:
4452:
4447:
4442:
4437:
4432:
4427:
4422:
4412:
4411:
4409:Zuclopenthixol
4406:
4401:
4396:
4391:
4381:
4376:
4371:
4366:
4361:
4356:
4351:
4346:
4341:
4336:
4331:
4326:
4321:
4316:
4311:
4306:
4301:
4296:
4293:+amitriptyline
4286:
4281:
4276:
4271:
4266:
4261:
4256:
4251:
4246:
4241:
4236:
4231:
4226:
4221:
4216:
4211:
4206:
4201:
4191:
4186:
4181:
4176:
4171:
4166:
4161:
4156:
4151:
4146:
4141:
4139:Chlorpromazine
4136:
4131:
4126:
4121:
4116:
4111:
4106:
4101:
4099:Acetophenazine
4096:
4086:
4084:
4080:
4079:
4077:
4076:
4071:
4066:
4061:
4056:
4051:
4046:
4041:
4036:
4031:
4026:
4021:
4016:
4011:
4006:
4001:
3996:
3991:
3986:
3981:
3976:
3971:
3966:
3961:
3956:
3951:
3946:
3941:
3936:
3931:
3926:
3921:
3916:
3911:
3906:
3901:
3896:
3891:
3886:
3881:
3876:
3871:
3866:
3856:
3855:
3850:
3845:
3840:
3835:
3830:
3825:
3820:
3815:
3805:
3795:
3794:
3789:
3784:
3776:
3774:-Phenylalanine
3768:
3760:
3755:
3750:
3745:
3735:
3734:
3729:
3724:
3719:
3714:
3704:
3703:
3698:
3693:
3688:
3683:
3678:
3673:
3668:
3663:
3658:
3653:
3643:
3642:
3637:
3632:
3627:
3622:
3616:Aminotetralins
3612:
3611:
3606:
3601:
3591:
3589:
3582:
3577:
3572:
3571:
3568:
3567:
3565:
3564:
3559:
3554:
3549:
3544:
3539:
3534:
3524:
3523:
3518:
3513:
3508:
3503:
3498:
3493:
3488:
3478:
3473:
3468:
3463:
3458:
3453:
3448:
3443:
3438:
3428:
3427:
3425:Zuclopenthixol
3422:
3412:
3407:
3402:
3397:
3394:+amitriptyline
3387:
3382:
3377:
3367:
3362:
3360:Chlorpromazine
3357:
3347:
3345:
3341:
3340:
3338:
3337:
3332:
3327:
3317:
3315:
3311:
3310:
3308:
3307:
3302:
3297:
3292:
3287:
3282:
3277:
3272:
3267:
3262:
3257:
3255:Isocorypalmine
3252:
3247:
3237:
3236:
3231:
3223:
3221:-Phenylalanine
3215:
3210:
3202:
3197:
3192:
3187:
3182:
3172:
3171:
3166:
3161:
3156:
3151:
3146:
3141:
3131:
3130:
3125:
3120:
3115:
3110:
3105:
3100:
3090:
3089:
3084:
3079:
3074:
3069:
3064:
3059:
3054:
3049:
3039:
3037:
3030:
3025:
3020:
3019:
3009:
3008:
3001:
2994:
2986:
2980:
2979:
2967:
2966:External links
2964:
2961:
2960:
2909:
2874:
2848:
2819:(6): 1171–82.
2799:
2750:
2709:
2682:
2639:
2587:
2552:
2525:(7): 1253–60.
2509:
2458:
2410:
2373:BMC Psychiatry
2356:
2305:
2286:(5): 1023–40.
2270:
2224:
2172:
2140:
2088:
2036:
1992:
1938:
1870:
1838:
1784:
1740:
1697:
1654:
1611:
1592:(1): 189–225.
1543:
1471:
1444:(1): 182–217.
1334:
1333:
1331:
1328:
1327:
1326:
1307:
1304:
1303:
1302:
1298:
1294:
1288:
1285:
1281:
1275:
1271:
1267:
1259:
1256:
1255:
1254:
1251:Metoclopramide
1248:
1240:
1234:
1226:
1223:
1222:
1221:
1212:
1206:
1202:
1198:
1192:
1188:
1184:
1180:
1174:
1170:
1164:
1160:
1156:
1152:
1148:
1144:
1138:
1133:
1132:and can bind D
1129:
1125:
1121:
1115:
1109:
1106:
1102:
1098:
1092:
1088:
1084:
1080:
1076:
1070:
1062:
1058:
1054:
1050:
1035:
1034:
1030:
1026:
1020:
1016:
1012:
1008:
1002:
998:
994:
983:
975:
972:
971:
970:
962:
958:
954:
950:
946:
940:
936:
932:
926:
923:
919:
915:
911:
905:
901:
897:
893:
887:
882:
877:
872:
867:
863:
859:
855:
851:
845:
841:
837:
833:
829:
823:
815:
811:
807:
803:
799:
793:
787:
773:
772:
769:
765:
761:
757:
753:
750:Chlorpromazine
747:
735:
723:
720:
718:
715:
714:
713:
709:
699:
694:
684:
679:
672:
666:
662:
656:
655:
654:
650:
647:
646:
645:
644:
643:
631:
630:
629:
628:
627:
618:
605:
604:
603:
584:
563:
560:
559:
558:
523:
519:
516:
515:
514:
508:
502:
498:
495:
494:
493:
490:
483:
477:
473:
470:
469:
468:
465:
462:
456:
450:
446:
443:
438:
432:
427:
424:
420:
416:
412:
409:
408:
407:
403:
402:In addition, D
400:
370:
367:Low levels of
363:
359:
356:
355:
354:
350:
347:
329:
326:olfactory bulb
322:frontal cortex
299:
293:
289:
286:
281:
277:
270:
267:
263:
259:
256:
251:
247:
239:
235:
219:
216:
181:antipsychotics
147:
146:
140:
139:
135:
134:
127:
121:
120:
119:External links
116:
115:
110:
104:
103:
98:
92:
91:
73:
69:
68:
64:
63:
54:
46:
45:
37:
36:
15:
9:
6:
4:
3:
2:
6349:
6338:
6335:
6334:
6332:
6317:
6314:
6312:
6309:
6307:
6304:
6300:
6297:
6295:
6292:
6291:
6290:
6289:
6281:
6277:
6274:
6272:
6269:
6267:
6264:
6262:
6259:
6257:
6254:
6253:
6252:
6251:
6247:
6246:
6244:
6242:
6238:
6232:
6229:
6227:
6224:
6222:
6219:
6215:
6212:
6210:
6207:
6205:
6202:
6201:
6200:
6197:
6196:
6193:
6190:
6188:
6185:
6182:
6181:
6179:
6176:
6169:
6165:
6155:
6152:
6150:
6147:
6145:
6142:
6140:
6137:
6135:
6132:
6130:
6127:
6125:
6122:
6120:
6117:
6115:
6114:Isometheptene
6112:
6110:
6107:
6105:
6102:
6100:
6097:
6095:
6092:
6090:
6087:
6085:
6082:
6080:
6077:
6075:
6072:
6071:
6069:
6065:
6057:
6054:
6053:
6052:
6051:
6043:
6039:
6036:
6034:
6031:
6030:
6029:
6028:
6020:
6019:
6017:
6015:
6009:
6003:
6000:
5998:
5995:
5993:
5990:
5989:
5987:
5985:
5979:
5969:
5968:Tridihexethyl
5966:
5964:
5961:
5959:
5956:
5954:
5953:Propantheline
5951:
5949:
5946:
5944:
5941:
5939:
5936:
5934:
5931:
5929:
5926:
5924:
5921:
5919:
5918:Methantheline
5916:
5914:
5911:
5909:
5906:
5904:
5901:
5899:
5896:
5894:
5893:Fenpiverinium
5891:
5889:
5886:
5884:
5881:
5879:
5876:
5875:
5873:
5869:
5863:
5857:
5854:
5852:
5849:
5847:
5844:
5842:
5839:
5837:
5834:
5832:
5829:
5827:
5824:
5822:
5821:Dicycloverine
5819:
5817:
5814:
5813:
5811:
5805:
5802:
5800:
5796:
5793:
5791:
5781:
5776:
5772:
5764:
5759:
5757:
5752:
5750:
5745:
5744:
5741:
5724:
5723:
5718:
5715:
5712:
5711:
5706:
5703:
5702:
5700:
5698:Miscellaneous
5696:
5686:
5683:
5681:
5674:
5672:
5669:
5667:
5664:
5661:
5658:
5657:
5655:
5651:
5645:
5642:
5640:
5637:
5635:
5632:
5630:
5627:
5626:
5624:
5622:
5618:
5611:
5608:
5605:
5602:
5600:
5597:
5595:
5592:
5591:
5589:
5587:
5583:
5576:
5573:
5571:
5567:
5564:
5562:
5558:
5555:
5551:
5548:
5547:
5545:
5542:
5540:
5536:
5533:
5532:
5530:
5528:
5524:
5514:
5511:
5508:
5504:
5501:
5498:
5494:
5491:
5490:
5488:
5486:
5485:Glutamatergic
5482:
5475:
5472:
5470:
5467:
5465:
5462:
5461:
5459:
5457:
5453:
5450:
5448:
5444:
5433:
5430:
5427:
5420:
5417:
5415:
5412:
5411:
5409:
5407:
5403:
5396:
5390:
5388:
5382:
5380:
5373:
5370:
5368:
5365:
5364:
5362:
5360:
5359:Histaminergic
5356:
5349:
5346:
5344:
5341:
5339:
5336:
5335:
5333:
5331:
5327:
5320:
5317:
5314:
5311:
5308:
5305:
5303:
5299:
5295:
5292:
5289:
5286:
5284:
5280:
5277:
5275:
5271:
5268:
5267:
5265:
5263:
5259:
5256:
5254:
5250:
5246:
5243:
5241:
5236:
5232:
5228:
5223:
5221:
5217:
5213:
5212:
5206:
5204:
5200:
5197:
5193:
5187:
5184:
5182:
5178:
5177:
5173:
5170:
5167:
5164:
5161:
5157:
5153:
5152:
5148:
5145:
5142:
5139:
5137:
5134:
5132:
5129:
5127:
5124:
5122:
5118:
5114:
5113:
5110:
5107:
5105:
5101:
5097:
5096:
5093:
5090:
5088:
5084:
5080:
5079:
5077:
5073:
5069:
5062:
5057:
5055:
5050:
5048:
5043:
5042:
5039:
5026:
5025:
5020:
5017:
5016:
5011:
5008:
5007:
5002:
4999:
4998:
4993:
4990:
4989:
4988:Serotonergics
4984:
4981:
4980:
4975:
4972:
4971:
4968:
4963:
4962:
4959:
4949:
4946:
4944:
4941:
4939:
4936:
4934:
4931:
4929:
4926:
4924:
4921:
4919:
4916:
4914:
4911:
4909:
4908:Sonepiprazole
4906:
4904:
4901:
4899:
4896:
4894:
4891:
4889:
4886:
4884:
4881:
4879:
4876:
4874:
4871:
4869:
4866:
4864:
4861:
4859:
4856:
4854:
4851:
4849:
4846:
4844:
4841:
4839:
4836:
4834:
4831:
4829:
4826:
4824:
4823:Iodobenzamide
4821:
4819:
4816:
4814:
4811:
4809:
4806:
4804:
4801:
4799:
4796:
4794:
4791:
4789:
4786:
4784:
4783:Bromocriptine
4781:
4779:
4776:
4774:
4771:
4769:
4766:
4764:
4760:
4757:
4756:
4753:
4750:
4748:
4745:
4743:
4740:
4738:
4735:
4733:
4729:
4726:
4725:
4722:
4719:
4717:
4714:
4712:
4709:
4707:
4704:
4702:
4699:
4697:
4694:
4692:
4689:
4687:
4684:
4682:
4679:
4677:
4674:
4672:
4669:
4667:
4664:
4662:
4659:
4657:
4656:Benzquinamide
4654:
4652:
4649:
4647:
4644:
4642:
4639:
4637:
4633:
4630:
4629:
4626:
4623:
4621:
4618:
4616:
4613:
4611:
4608:
4606:
4603:
4601:
4598:
4596:
4593:
4591:
4588:
4586:
4583:
4581:
4578:
4576:
4573:
4571:
4568:
4566:
4563:
4561:
4558:
4556:
4553:
4551:
4548:
4545:
4541:
4538:
4536:
4533:
4531:
4528:
4526:
4523:
4521:
4518:
4516:
4513:
4511:
4508:
4506:
4503:
4501:
4498:
4496:
4493:
4491:
4488:
4486:
4483:
4481:
4478:
4476:
4475:DHA-clozapine
4473:
4471:
4468:
4466:
4463:
4461:
4458:
4456:
4453:
4451:
4448:
4446:
4443:
4441:
4438:
4436:
4433:
4431:
4428:
4426:
4423:
4421:
4417:
4414:
4413:
4410:
4407:
4405:
4402:
4400:
4399:Trifluperidol
4397:
4395:
4392:
4389:
4385:
4382:
4380:
4377:
4375:
4372:
4370:
4367:
4365:
4362:
4360:
4359:Thiopropazate
4357:
4355:
4352:
4350:
4347:
4345:
4342:
4340:
4339:Sulforidazine
4337:
4335:
4332:
4330:
4327:
4325:
4322:
4320:
4317:
4315:
4312:
4310:
4307:
4305:
4302:
4300:
4297:
4294:
4290:
4287:
4285:
4282:
4280:
4277:
4275:
4272:
4270:
4267:
4265:
4262:
4260:
4257:
4255:
4252:
4250:
4247:
4245:
4242:
4240:
4239:Levosulpiride
4237:
4235:
4232:
4230:
4227:
4225:
4222:
4220:
4217:
4215:
4212:
4210:
4209:Fluprothixene
4207:
4205:
4202:
4199:
4195:
4192:
4190:
4187:
4185:
4182:
4180:
4177:
4175:
4172:
4170:
4167:
4165:
4162:
4160:
4157:
4155:
4152:
4150:
4147:
4145:
4142:
4140:
4137:
4135:
4132:
4130:
4127:
4125:
4122:
4120:
4117:
4115:
4112:
4110:
4107:
4105:
4102:
4100:
4097:
4095:
4091:
4088:
4087:
4085:
4081:
4075:
4072:
4070:
4067:
4065:
4062:
4060:
4057:
4055:
4052:
4050:
4047:
4045:
4042:
4040:
4037:
4035:
4032:
4030:
4027:
4025:
4022:
4020:
4017:
4015:
4012:
4010:
4007:
4005:
4002:
4000:
3997:
3995:
3992:
3990:
3987:
3985:
3984:Phencyclidine
3982:
3980:
3977:
3975:
3972:
3970:
3967:
3965:
3962:
3960:
3957:
3955:
3952:
3950:
3947:
3945:
3942:
3940:
3937:
3935:
3932:
3930:
3927:
3925:
3922:
3920:
3917:
3915:
3912:
3910:
3907:
3905:
3902:
3900:
3897:
3895:
3892:
3890:
3887:
3885:
3882:
3880:
3877:
3875:
3872:
3870:
3867:
3865:
3861:
3858:
3857:
3854:
3851:
3849:
3846:
3844:
3841:
3839:
3836:
3834:
3833:Brilaroxazine
3831:
3829:
3828:Brexpiprazole
3826:
3824:
3821:
3819:
3816:
3813:
3809:
3806:
3804:
3800:
3797:
3796:
3793:
3790:
3788:
3785:
3783:
3777:
3775:
3769:
3767:
3761:
3759:
3756:
3754:
3751:
3749:
3746:
3744:
3740:
3737:
3736:
3733:
3730:
3728:
3725:
3723:
3722:Dihydrexidine
3720:
3718:
3715:
3713:
3709:
3706:
3705:
3702:
3699:
3697:
3694:
3692:
3689:
3687:
3684:
3682:
3679:
3677:
3674:
3672:
3669:
3667:
3664:
3662:
3659:
3657:
3654:
3652:
3651:Bromocriptine
3648:
3645:
3644:
3641:
3638:
3636:
3633:
3631:
3628:
3626:
3623:
3621:
3617:
3614:
3613:
3610:
3607:
3605:
3602:
3600:
3596:
3593:
3592:
3590:
3586:
3583:
3581:
3573:
3563:
3560:
3558:
3555:
3553:
3550:
3548:
3545:
3543:
3540:
3538:
3535:
3533:
3529:
3526:
3525:
3522:
3519:
3517:
3514:
3512:
3509:
3507:
3504:
3502:
3499:
3497:
3494:
3492:
3489:
3486:
3482:
3479:
3477:
3476:Norquetiapine
3474:
3472:
3469:
3467:
3464:
3462:
3459:
3457:
3456:DHA-clozapine
3454:
3452:
3449:
3447:
3444:
3442:
3439:
3437:
3433:
3430:
3429:
3426:
3423:
3420:
3416:
3413:
3411:
3408:
3406:
3403:
3401:
3398:
3395:
3391:
3388:
3386:
3383:
3381:
3378:
3375:
3371:
3368:
3366:
3363:
3361:
3358:
3356:
3352:
3349:
3348:
3346:
3342:
3336:
3333:
3331:
3328:
3326:
3322:
3319:
3318:
3316:
3312:
3306:
3303:
3301:
3298:
3296:
3293:
3291:
3288:
3286:
3283:
3281:
3278:
3276:
3273:
3271:
3268:
3266:
3263:
3261:
3258:
3256:
3253:
3251:
3248:
3246:
3242:
3239:
3238:
3235:
3232:
3230:
3224:
3222:
3216:
3214:
3211:
3209:
3203:
3201:
3198:
3196:
3193:
3191:
3188:
3186:
3183:
3181:
3177:
3174:
3173:
3170:
3167:
3165:
3162:
3160:
3157:
3155:
3154:Dihydrexidine
3152:
3150:
3147:
3145:
3142:
3140:
3136:
3133:
3132:
3129:
3126:
3124:
3121:
3119:
3116:
3114:
3111:
3109:
3106:
3104:
3101:
3099:
3095:
3092:
3091:
3088:
3085:
3083:
3080:
3078:
3075:
3073:
3070:
3068:
3065:
3063:
3060:
3058:
3055:
3053:
3050:
3048:
3044:
3041:
3040:
3038:
3034:
3031:
3029:
3021:
3017:
3014:
3007:
3002:
3000:
2995:
2993:
2988:
2987:
2984:
2977:
2973:
2970:
2969:
2956:
2952:
2947:
2942:
2937:
2932:
2928:
2924:
2920:
2913:
2905:
2901:
2897:
2893:
2889:
2885:
2878:
2862:
2858:
2852:
2844:
2840:
2835:
2830:
2826:
2822:
2818:
2814:
2810:
2803:
2795:
2791:
2786:
2781:
2777:
2773:
2770:(3): 248–62.
2769:
2765:
2761:
2754:
2746:
2742:
2737:
2732:
2729:(4): 379–90.
2728:
2724:
2720:
2713:
2705:
2701:
2697:
2693:
2686:
2678:
2674:
2670:
2666:
2662:
2658:
2654:
2650:
2643:
2635:
2631:
2626:
2621:
2617:
2613:
2610:(2): 163–74.
2609:
2605:
2601:
2594:
2592:
2583:
2579:
2575:
2571:
2567:
2563:
2556:
2548:
2544:
2540:
2536:
2532:
2528:
2524:
2520:
2513:
2505:
2501:
2496:
2491:
2486:
2481:
2477:
2473:
2469:
2462:
2454:
2450:
2445:
2440:
2436:
2432:
2428:
2421:
2414:
2406:
2402:
2397:
2392:
2387:
2382:
2378:
2374:
2370:
2363:
2361:
2352:
2348:
2343:
2338:
2333:
2328:
2324:
2320:
2316:
2309:
2301:
2297:
2293:
2289:
2285:
2281:
2274:
2266:
2262:
2257:
2252:
2248:
2244:
2240:
2233:
2231:
2229:
2220:
2216:
2211:
2206:
2202:
2198:
2194:
2190:
2186:
2179:
2177:
2168:
2164:
2160:
2156:
2149:
2147:
2145:
2136:
2132:
2127:
2122:
2118:
2114:
2110:
2106:
2102:
2095:
2093:
2084:
2080:
2075:
2070:
2066:
2062:
2055:
2053:
2051:
2049:
2047:
2045:
2043:
2041:
2032:
2028:
2024:
2020:
2017:(3): 545–63.
2016:
2012:
2008:
2001:
1999:
1997:
1988:
1984:
1979:
1974:
1970:
1966:
1963:(3): 265–82.
1962:
1958:
1954:
1947:
1945:
1943:
1934:
1930:
1925:
1920:
1915:
1910:
1906:
1902:
1898:
1891:
1889:
1887:
1885:
1883:
1881:
1879:
1877:
1875:
1866:
1862:
1858:
1854:
1847:
1845:
1843:
1834:
1830:
1826:
1822:
1818:
1814:
1811:(4): 353–62.
1810:
1806:
1799:
1797:
1795:
1793:
1791:
1789:
1780:
1776:
1772:
1768:
1764:
1760:
1756:
1752:
1744:
1736:
1732:
1728:
1724:
1720:
1716:
1713:(6): 605–16.
1712:
1708:
1701:
1693:
1689:
1685:
1681:
1677:
1673:
1670:(5): 188–93.
1669:
1665:
1658:
1650:
1646:
1642:
1638:
1634:
1630:
1627:(4): 515–31.
1626:
1622:
1615:
1607:
1603:
1599:
1595:
1591:
1587:
1580:
1578:
1576:
1574:
1572:
1570:
1568:
1566:
1564:
1562:
1560:
1558:
1556:
1554:
1552:
1550:
1548:
1539:
1535:
1531:
1527:
1523:
1519:
1512:
1510:
1508:
1506:
1504:
1502:
1500:
1498:
1496:
1494:
1492:
1490:
1488:
1486:
1484:
1482:
1480:
1478:
1476:
1467:
1463:
1459:
1455:
1451:
1447:
1443:
1439:
1432:
1430:
1428:
1426:
1424:
1422:
1420:
1418:
1416:
1414:
1412:
1410:
1408:
1406:
1404:
1402:
1400:
1398:
1396:
1394:
1392:
1390:
1388:
1386:
1384:
1382:
1380:
1378:
1376:
1374:
1372:
1370:
1368:
1366:
1364:
1362:
1360:
1358:
1356:
1354:
1352:
1350:
1348:
1346:
1344:
1342:
1340:
1335:
1325:
1321:
1317:
1313:
1310:
1309:
1292:
1289:
1279:
1276:
1265:
1262:
1261:
1252:
1249:
1246:
1245:gastroparesis
1238:
1235:
1232:
1229:
1228:
1219:
1210:
1207:
1196:
1193:
1178:
1175:
1168:
1165:
1142:
1139:
1119:
1116:
1113:
1110:
1096:
1093:
1074:
1071:
1068:
1048:
1045:
1044:
1039:
1024:
1021:
1006:
1003:
992:
989:
988:
987:
981:
968:
944:
941:
930:
927:
909:
906:
891:
888:
886:
883:
881:
878:
876:
873:
871:
868:
849:
846:
827:
824:
821:
797:
794:
791:
788:
786:
783:
782:
777:
751:
748:
745:
741:
733:
730:
729:
728:
707:
703:
700:
698:
695:
693:
689:
685:
683:
680:
677:
673:
670:
667:
660:
657:
648:
641:
640:
638:
635:
634:
632:
625:
624:
622:
619:
617:
613:
612:beta blockers
609:
606:
601:
600:
598:
594:
593:
591:
590:
588:
585:
580:
576:
573:
572:
571:
569:
557:
553:
549:
546:
545:
544:
542:
538:
534:
530:
529:schizophrenia
512:
505:
504:
491:
487:
480:
479:
466:
463:
460:
453:
452:
442:
436:
401:
398:
394:
393:dentate gyrus
390:
386:
382:
378:
374:
366:
365:
348:
346:
342:
338:
334:
330:
327:
323:
319:
315:
311:
307:
303:
296:
295:
285:
275:
255:
245:
233:
224:
215:
213:
209:
205:
201:
198:
194:
190:
186:
185:schizophrenia
182:
178:
174:
171:which blocks
170:
166:
162:
158:
154:
145:
141:
136:
132:
128:
126:
122:
117:
114:
111:
109:
105:
102:
99:
97:
93:
89:
85:
81:
77:
76:Schizophrenia
74:
70:
65:
61:
57:
52:
47:
44:
43:
38:
31:
26:
22:
6282:
6249:
6248:
6198:
6183:
6089:Diisopromine
6044:
6021:
5928:Oxyphenonium
5908:Isopropamide
5846:Piperidolate
5831:Dihexyverine
5720:
5708:
5406:Serotonergic
5342:
5330:Dopaminergic
5209:
5022:
5013:
5004:
4995:
4986:
4977:
4966:
4965:
4918:Stepholidine
4913:Spiroxatrine
4903:Seridopidine
4898:SB-277,011-A
4818:Fenfluramine
4778:Bromerguride
4758:
4752:Trimipramine
4747:Propiomazine
4727:
4706:Promethazine
4701:Metopimazine
4631:
4550:Paliperidone
4495:Fluperlapine
4485:Elopiprazole
4450:Clocapramine
4440:Carpipramine
4415:
4369:Thioridazine
4329:Prothipendyl
4289:Perphenazine
4249:Mesoridazine
4224:Homopipramol
4214:Fluspirilene
4204:Fluphenazine
4159:Clothixamide
4154:Clopenthixol
4129:Chloracizine
4124:Butaperazine
4094:Acepromazine
4089:
4049:Salvinorin A
3859:
3853:Norclozapine
3848:Lumateperone
3808:Aripiprazole
3798:
3738:
3707:
3661:Chanoclavine
3646:
3615:
3594:
3527:
3491:Paliperidone
3471:Norclozapine
3461:Fluperlapine
3431:
3405:Thioridazine
3390:Perphenazine
3380:Fluphenazine
3350:
3320:
3295:Stepholidine
3240:
3175:
3134:
3093:
3043:Benzazepines
3042:
2926:
2923:Biomolecules
2922:
2912:
2887:
2883:
2877:
2867:25 September
2865:. Retrieved
2860:
2851:
2816:
2812:
2802:
2767:
2763:
2753:
2726:
2722:
2712:
2695:
2691:
2685:
2655:(1): 19–27.
2652:
2648:
2642:
2607:
2603:
2565:
2555:
2522:
2518:
2512:
2475:
2471:
2461:
2426:
2413:
2376:
2372:
2322:
2318:
2308:
2283:
2279:
2273:
2246:
2242:
2192:
2188:
2158:
2111:(1): 41–47.
2108:
2104:
2064:
2014:
2010:
1960:
1956:
1904:
1900:
1856:
1852:
1808:
1804:
1754:
1750:
1743:
1710:
1706:
1700:
1667:
1663:
1657:
1624:
1620:
1614:
1589:
1585:
1524:(1): 25–43.
1521:
1517:
1441:
1437:
1211:blocks the D
1141:Paliperidone
1023:Aripiprazole
982:receptor 5HT
977:
943:Thioridazine
885:Perphenazine
870:Fluspirilene
826:Fluphenazine
785:Clopenthixol
725:
706:dopaminergic
621:Parkinsonism
565:
562:Side effects
521:
437:unlike the D
429:
377:hypothalamus
333:hypothalamus
272:
229:
164:
160:
156:
152:
150:
138:Legal status
40:
6294:Cinitapride
6271:Domperidone
6241:Propulsives
6204:Scopolamine
6192:Hyoscyamine
6149:Trepibutone
6144:Tiropramide
6109:Idanpramine
6038:Cilansetron
6027:antagonists
5992:Drotaverine
5938:Pipenzolate
5933:Penthienate
5913:Mepenzolate
5903:Hexocyclium
5856:Trimebutine
5809:amino group
5722:Amino acids
5621:Opioidergic
5527:Cholinergic
5240:transporter
5220:Ion channel
5156:Transporter
5100:Ion channel
4979:Adrenergics
4883:Pridopidine
4868:Nafadotride
4853:Metergoline
4768:Alpiropride
4716:Trazpiroben
4686:Hydroxyzine
4681:Eticlopride
4676:Domperidone
4646:Alimemazine
4620:Ziprasidone
4615:Zicronapine
4610:Veralipride
4595:Tefludazine
4585:Risperidone
4580:Remoxipride
4565:Pipotiazine
4555:Perospirone
4544:+fluoxetine
4535:Ocaperidone
4530:Mosapramine
4515:Mazapertine
4505:Iloperidone
4500:Gevotroline
4490:Flumezapine
4470:Cyamemazine
4455:Clorotepine
4435:Blonanserin
4420:Amisulpride
4374:Thiothixene
4309:Pipamperone
4274:Perathiepin
4269:Penfluridol
4264:Nemonapride
4219:Haloperidol
4198:+melitracen
4164:Clopimozide
4114:Bromperidol
4083:Antagonists
4074:WAY-100,635
4019:Quinelorane
4014:Quinagolide
3994:Pramipexole
3959:Pardoprunox
3944:Mesulergine
3934:Flibanserin
3924:Dizocilpine
3904:Armodafinil
3894:Apomorphine
3838:Cariprazine
3812:+sertraline
3753:Etilevodopa
3676:Ergocornine
3671:Epicriptine
3656:Cabergoline
3609:Rimantadine
3595:Adamantanes
3516:Ziprasidone
3511:Zicronapine
3506:Tefludazine
3501:Risperidone
3485:+fluoxetine
3466:Iloperidone
3441:Clorotepine
3410:Thiothixene
3400:Pifluthixol
3374:+melitracen
3344:Antagonists
3250:Apomorphine
3195:Etilevodopa
3169:Doxanthrine
3159:Dinapsoline
3098:Cabergoline
2861:AdisInsight
2325:: 3007–17.
2249:(1): 1–13.
1278:Nafadotride
1264:Eticlopride
1231:Domperidone
1209:Ziprasidone
1177:Risperidone
1167:Remoxipride
1095:Nemonapride
1067:neutropenia
991:Amisulpride
875:Penfluridol
848:Flupentixol
796:Haloperidol
389:hippocampus
345:hippocampus
308:as well as
204:antiemetics
200:antagonists
144:In Wikidata
6311:Ilebopride
6306:Acotiamide
6266:Clebopride
6261:Bromopride
6256:Alizapride
6168:Belladonna
6139:Simeticone
6104:Fenpiprane
6099:Fenoverine
6079:Caroverine
6002:Papaverine
5997:Moxaverine
5984:inhibitors
5963:Timepidium
5888:Diphemanil
5866:Quaternary
5851:Rociverine
5836:Mebeverine
5826:Difemerine
5786:functional
5769:Drugs for
5570:Ganglionic
5561:Muscarinic
5539:Muscarinic
5262:Adrenergic
5131:Antagonist
4888:Raclopride
4878:PNU-99,194
4873:Nuciferine
4813:Fananserin
4808:Fallypride
4737:Nefazodone
4666:Clebopride
4661:Bromopride
4651:Alizapride
4605:Tiospirone
4600:Tenilapine
4590:Sertindole
4575:Quetiapine
4570:Piquindone
4540:Olanzapine
4510:Lurasidone
4480:Dixyrazine
4445:Cinuperone
4404:Zetidoline
4379:Timiperone
4354:Teflutixol
4349:Sultopride
4189:Fluotracen
4184:Flucindole
4179:Fluanisone
4174:Fluacizine
4169:Droperidol
4149:Ciclindole
4119:Butaclamol
4109:Benperidol
4069:Umespirone
4064:Talipexole
4059:Sumanirole
4054:SKF-83,959
4039:Ropinirole
4024:Quinpirole
3979:PF-592,379
3974:PF-219,061
3969:PD-168,077
3964:PD-128,907
3929:Esketamine
3919:CP-226,269
3914:Captodiame
3899:Arketamine
3823:Bifeprunox
3787:Melevodopa
3748:Dopexamine
3727:Dinoxyline
3681:Lergotrile
3635:Rotigotine
3599:Amantadine
3496:Quetiapine
3481:Olanzapine
3446:Clotiapine
3355:Butaclamol
3290:SKF-89,626
3285:SKF-89,145
3280:Rotigotine
3270:PF 6669571
3265:PF-6649751
3260:Nuciferine
3213:Melevodopa
3190:Dopexamine
3164:Dinoxyline
3103:CY-208,243
3087:Zelandopam
3077:SKF-83,959
3072:SKF-82,958
3067:SKF-81,297
3062:SKF-77,434
3057:SKF-38,393
3052:Fenoldopam
3016:modulators
2929:(1): 104.
2890:(1): 1–3.
2159:StatPearls
1907:: 656370.
1330:References
1312:Mesdopetam
1291:Raclopride
1237:Bromopride
1118:Quetiapine
1112:Olanzapine
790:Droperidol
732:Benperidol
727:activity.
678:resistance
341:cerebellum
328:and retina
42:Drug class
6316:Mosapride
6299:Cisapride
6134:Proxazole
6056:Mosapride
6033:Alosetron
6011:Acting on
5958:Tiemonium
5948:Prifinium
5923:Otilonium
5878:Benzilone
5871:compounds
5816:Camylofin
5790:disorders
5783:Drugs for
5717:Precursor
5566:Nicotinic
5544:Nicotinic
5456:GABAergic
5181:Precursor
5166:Inhibitor
5092:Inhibitor
4967:See also:
4948:Yohimbine
4928:Terguride
4893:Sarizotan
4838:L-745,870
4833:L-741,626
4788:Buspirone
4742:Opipramol
4732:Amoxapine
4525:Molindone
4520:Melperone
4465:Clozapine
4425:Asenapine
4344:Sulpiride
4324:Promazine
4314:Preclamol
4229:Lenperone
4104:Azaperone
4044:Roxindole
4034:Ro10-5824
4009:Pukateine
3999:Preclamol
3989:Piribedil
3949:Modafinil
3889:Aplindore
3884:Adrafinil
3782:-Tyrosine
3758:Ibopamine
3701:Terguride
3696:Pergolide
3647:Ergolines
3630:8-OH-PBZI
3625:7-OH-DPAT
3620:5-OH-DPAT
3604:Memantine
3562:SCH-23390
3557:Perlapine
3532:Berupipam
3451:Clozapine
3436:Asenapine
3335:Mevidalen
3300:Tavapadon
3229:-Tyrosine
3200:Ibopamine
3128:Terguride
3123:Pergolide
3094:Ergolines
2677:260238868
1320:psychosis
1047:Clozapine
1041:Clozapine
1005:Asenapine
980:serotonin
929:Sulpiride
908:Spiperone
904:receptors
740:serotonin
738:and some
608:Akathisia
597:dystonias
548:Melatonin
511:receptors
501:receptors
486:receptors
476:receptors
459:receptors
449:receptors
373:receptors
362:receptors
302:receptors
292:receptors
6331:Category
6288:agonists
6187:Atropine
6074:Alverine
6050:agonists
5883:Bevonium
5868:ammonium
5807:Tertiary
5705:Cofactor
5575:Muscular
5235:Receptor
5186:Cofactor
5172:Releaser
5160:Enhancer
5154:♦
5117:Receptor
5115:♦
5098:♦
5081:♦
4938:Tiapride
4848:LEK-8829
4773:Azapride
4691:Itopride
4625:Zotepine
4304:Pimozide
4279:Perazine
4254:Moperone
4244:Loxapine
3954:OSU-6162
3939:Ketamine
3869:A-412997
3717:Ciladopa
3712:2-OH-NPA
3686:Lisuride
3588:Agonists
3552:Odapipam
3537:Ecopipam
3521:Zotepine
3385:Loxapine
3118:Lisuride
3113:LEK-8829
3082:Trepipam
3047:6-Br-APB
3036:Agonists
2955:33466844
2904:38116733
2843:26899245
2794:18801115
2745:14871277
2704:14728084
2669:10721880
2634:25943458
2582:24249315
2539:27121764
2504:25859275
2453:24346956
2444:11330668
2405:26220447
2351:26674884
2300:22494521
2265:23295003
2219:15846648
2167:30137788
2135:23983836
2083:14972081
2031:24011886
1987:11607043
1933:24995318
1865:10811237
1825:25516373
1779:29375454
1771:19145986
1735:25508148
1727:12043836
1692:22686973
1684:17368565
1649:30902536
1641:16848689
1538:16613552
1458:21303898
1197:blocks D
1195:Tiapride
1137:effects.
1073:Loxapine
890:Pimozide
880:Perazine
717:Examples
697:Sedation
653:receptor
568:dopamine
541:vomiting
337:thalamus
318:amygdala
314:striatum
212:vomiting
197:dopamine
96:ATC code
88:vomiting
5943:Poldine
5662:(AdoRI)
5612:(eCBRI)
5195:Classes
5121:Agonist
5109:Blocker
5087:Inducer
4803:F-15063
4641:AS-8112
4430:BL-1020
4259:Naranol
4029:RDS-127
3879:ABT-724
3874:ABT-670
3843:F-15063
3792:XP21279
3245:A-68930
3234:XP21279
3180:BCO-001
3144:A-86929
3139:A-77636
2946:7830622
2834:4844650
2785:2753830
2625:4488186
2547:4402288
2495:4391595
2396:4518630
2379:: 179.
2342:4675633
2210:7017029
2126:3726098
1978:6741677
1924:4065707
1833:8345032
1606:9457173
1466:2545878
1293:binds D
1280:binds D
1266:binds D
1179:binds D
1169:binds D
1143:binds D
1120:binds D
1097:binds D
1075:binds D
1049:binds D
1025:binds D
1007:binds D
993:binds D
945:binds D
931:binds D
910:binds D
892:binds D
862:, and D
850:binds D
844:as well
828:binds D
798:binds D
752:binds D
734:binds D
688:obesity
676:insulin
179:. Most
131:D012559
5788:bowel
5606:(eCBE)
5203:Enzyme
5104:Opener
5083:Enzyme
4943:UH-232
4923:SV-293
4759:Others
3909:BP-897
3860:Others
3640:UH-232
3528:Others
3241:Others
2978:(MeSH)
2953:
2943:
2902:
2841:
2831:
2792:
2782:
2743:
2702:
2675:
2667:
2632:
2622:
2580:
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2537:
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2207:
2165:
2133:
2123:
2081:
2029:
1985:
1975:
1931:
1921:
1863:
1831:
1823:
1777:
1769:
1733:
1725:
1690:
1682:
1647:
1639:
1604:
1536:
1464:
1456:
595:Acute
537:nausea
208:nausea
191:, and
159:and a
90:, etc.
84:nausea
6067:Other
5719:(see
5707:(see
5653:Other
5476:(GRI)
5434:(SRI)
5350:(DRI)
5321:(NRI)
5237:&
5149:(NAM)
5143:(PAM)
5075:Types
4763:3-PPP
3864:3-PPP
3580:-like
3028:-like
2673:S2CID
2543:S2CID
2423:(PDF)
1829:S2CID
1775:S2CID
1731:S2CID
1688:S2CID
1645:S2CID
1462:S2CID
1297:and D
1284:and D
1270:and D
1201:and D
1187:and D
1159:and D
1151:and D
1128:and D
1105:and D
1083:and D
1061:and D
1053:and D
1015:and D
997:and D
961:and D
953:and D
935:and D
918:and D
896:and D
840:and D
832:and D
814:and D
806:and D
768:and D
489:area.
423:and D
280:and D
266:and D
240:s/olf
6284:5-HT
6046:5-HT
6023:5-HT
5507:NMDA
5497:AMPA
5423:5-HT
5225:See
5208:see
5174:(RA)
5168:(RI)
5162:(RE)
4798:EEDQ
3542:EEDQ
3330:DPTQ
3325:DETQ
3314:PAMs
2951:PMID
2900:PMID
2869:2024
2839:PMID
2790:PMID
2741:PMID
2700:PMID
2665:PMID
2630:PMID
2578:PMID
2535:PMID
2500:PMID
2449:PMID
2401:PMID
2347:PMID
2296:PMID
2261:PMID
2215:PMID
2193:2005
2163:PMID
2131:PMID
2079:PMID
2027:PMID
1983:PMID
1929:PMID
1905:2014
1861:PMID
1821:PMID
1767:PMID
1723:PMID
1680:PMID
1637:PMID
1602:PMID
1534:PMID
1454:PMID
1318:and
690:and
614:and
539:and
395:and
383:and
343:and
324:and
210:and
202:are
169:drug
125:MeSH
101:N05A
86:and
5775:A03
3691:LSD
2941:PMC
2931:doi
2892:doi
2829:PMC
2821:doi
2780:PMC
2772:doi
2731:doi
2657:doi
2620:PMC
2612:doi
2570:doi
2527:doi
2490:PMC
2480:doi
2439:PMC
2431:doi
2391:PMC
2381:doi
2337:PMC
2327:doi
2288:doi
2251:doi
2205:PMC
2197:doi
2121:PMC
2113:doi
2069:doi
2019:doi
1973:PMC
1965:doi
1919:PMC
1909:doi
1813:doi
1759:doi
1715:doi
1672:doi
1629:doi
1594:doi
1526:doi
1446:doi
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252:i/o
175:by
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