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Edgewood Arsenal human experiments

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recreational dose, and the highest dose exceeded fifteen times the typical recreational dose. Because of limited documentation, it is difficult to ascertain which experiments occurred at which installations, but available documentation describes several general types of experiments; which included presenting individuals with radar symbols for interpretation, having them track a simulated aircraft, having them read a map, having them interpret meteorological data, and having them attempt to defend an installation against a simulated hostile air craft attack with 40-mm antiaircraft automatic weapons. Results varied between experiments, but typically showed significant impairment at all doses, with impairment increasing as dose did.
712:, which oversees the IOM, sent a questionnaire to all of the former volunteers that could be located, approximately 60% of the total. The lack of a detailed record hampered the investigation. The study could not rule out long-term health effects related to exposure to the nerve agents. It concluded that "Whether the subjects at Edgewood incurred these changes and to what extent they might now show these effects are not known". With regard specifically to BZ and related compounds, the IOM study concluded that "available data suggest that long-term toxic effects and/or delayed sequellae are unlikely". 870:
and vacated trial. The court granted the plaintiffs partial summary judgment concerning the notice claim: summarily adjudicating in plaintiffs' favor, finding that "the Army has an ongoing duty to warn" and ordering "the Army, through the DVA or otherwise, to provide test subjects with newly acquired information that may affect their well-being that it has learned since its original notification, now and in the future as it becomes available". The court granted the defendants' motion for summary judgment with respect to the other claims.
31: 788: 4199: 894: 101:(DoD). Some of the volunteers exhibited symptoms at the time of exposure to these agents but long-term follow-up was not planned as part of the DoD studies. The experiments were abruptly terminated by the Army in late 1975 amidst an atmosphere of scandal and recrimination as lawmakers accused researchers of questionable ethics. Many official government reports and civilian lawsuits followed in the wake of the controversy. 631:
congenital heart disease in offspring of the experimental subjects, and neuropsychological abnormalities in 9% of the participants which could not be explained by etiological explanations other than LSD exposure, most of which were considered mild. It is reported that all testing of LSD at Edgewood Arsenal and in general on behalf of the Army Chemical Corps was abandoned on or around April 1963.
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Arsenal, Maryland; Dugway Proving Ground, Utah; and Forts Benning, Bragg, and McClellan. In total, Army documents identified 7,120 Army and Air Force personnel who participated in these tests. Further, GAO concluded that precise information on the scope and the magnitude of tests involving human subjects was not available, and the exact number of human subjects might never be known.
666:, was called before Congress and chastised by outraged lawmakers, who questioned the absence of follow-up care for the human volunteers. An Army investigation subsequently found no evidence of serious injuries or deaths associated with the MRVP, but deplored both the recruiting process and the informed consent approach, which they characterized as "suggest possible coercion". 574:. This action can be precipitated through a variety of mechanisms, including directly binding and deactivating the anticholinesterase itself, blocking the reaction between the anticholinesterase and the acetylcholinesterase, changing the release of acetylcholine, blocking acetylcholine's cholinolytic effect, or by increasing the excretion of the anticholinesterase. 34: 33: 38: 37: 32: 39: 881:(AR 70-25) created an independent duty to provide ongoing medical care to veterans who participated in U.S. chemical and biological testing programs. The prior finding held that the Army has an ongoing duty to seek out and provide "notice" to former test participants of any new information that could potentially affect their health. 36: 869:
On July 24, 2013, United States District Court Judge Claudia Wilken issued an order granting in part and denying in part plaintiffs' motion for summary judgment and granting in part and denying in part defendants' motion for summary judgment. The court resolved all of the remaining claims in the case
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In the Army's tests, as with those of the CIA, individual rights were ... subordinated to national security considerations; informed consent and follow-up examinations of subjects were neglected in efforts to maintain the secrecy of the tests. Finally, the command and control problems which were
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publicly asserted that many "forms of chemical and allied warfare as more 'humane' than existing weapons. For example, certain types of 'psychochemicals' would make it possible to paralyze temporarily entire population centers without damage to homes and other structures." Soviet advances in the same
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Unlike the CIA program, research subjects all signed informed consent forms, both a general one and another related to any experiment they were to participate in. Experiments were carried out with safety of subjects a principal focus. At Edgewood, even at the highest doses it often took an hour or
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in 1962. Lieberman, while acknowledging that "most of the military data" on the research ongoing at the Army Chemical Center was "secret and unpublished", asserted that "There are moral imponderables, such as whether insanity, temporary or permanent, is a more 'humane' military threat than the usual
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began conducting research using the aforementioned nerve gases. These studies included a classified human subjects component at least as early as 1948, when "psychological reactions" were documented in Edgewood technicians. Initially, such studies focused solely on the lethality of the gases and its
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article, dated July 23, 1975, by Bill Richards ("6,940 Took Drugs") reported that a top civilian drug researcher for the Army said a total of 6,940 servicemen had been involved in Army chemical and drug experiments, and that, furthermore, the tests were proceeding at Edgewood Arsenal as of the date
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Case No. CV-09-0037-CW, U.S.D.C. (N.D. Cal. 2009), the plaintiffs did not seek monetary damages. Instead, they sought only declaratory and injunctive relief and redress for what they claimed was several decades of neglect and the U.S. government's use of them as human guinea pigs in chemical and
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The committee's understanding is that additional, and potentially relevant, material on SHAD tests exists and remains classified. The IOM committee requested declassification of 21 additional elements from at least nine documents from DoD in August 2012. In January 2014, an additional request was
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Available data from both experiment patients and pharmaceutical research indicates that short-term exposure to anticholinergic compounds, especially the extremely limited exposures described in the documentation is associated with no long-term effects. It is important to note however, that in the
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Much of the experimentation at Edgewood Arsenal surrounded the modulation of Acetylcholine or Acetylcholinesterase, or the deactivation and reactivation of substances which did the same. These experiments represented a significant enough proportion of the total experimentation to earn a dedicated
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Throughout recorded history, wars have been characterized by death, human misery, and the destruction of property; each major conflict being more catastrophic than the one preceding it ... I am convinced that it is possible, by means of the techniques of psychochemical warfare, to conquer an
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Over a period of 20 years, more than 7,000 volunteers spent an estimated total of 14,000 months at Edgewood Arsenal. To my knowledge, not one of them died or suffered a serious illness or permanent injury. That adds up to 1,167 man-years of survival. Statistically, at least one out of a thousand
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Available data describes a wide range of doses used in the experiments, from approximately 2μg/kg to 16μg/kg A typical dose for recreational use is around 100μg, or about 1.1μg/kg for the average adult male in the U.S., meaning the lowest dose used in experimentation was almost twice the typical
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Available data from the experiments concluded that long term effects from LSD exposure in not only the Edgewood Arsenal Experiments, but in the other associated experiments conducted concurrently by the Army Chemical Corps as well were minimal, with the exception of a possible small increase in
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Available data from the experiments and from prescribing information from modern marketing of these substances concludes that little risk exists of long term effects from exposure. It is noted, however, in both the prescribing information for modern variants and in toxicological research on the
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Psychochemical Conference informed the Department of Defense that human trials were indicated. In 1957, the first report of such trials were received, detailing a four-person experiment wherein they attempted to successfully decontaminate themselves of a mock agent while under the influence of
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The 1976 report on the matter identifies the sole objective of the psychochemical experiments as determining the impact on morale and efficacy such agents would have on military units. It appears that these experiments specifically were first called for in 1954 after the attendees of the First
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we reported that the Army Chemical Corps conducted a classified medical research program for developing incapacitating agents. This program involved testing nerve agents, nerve agent antidotes, psycho chemicals, and irritants. The chemicals were given to volunteer service members at Edgewood
843:, and eight Edgewood veterans or their families against CIA, the U.S. Army, and other agencies. The complaint asked the court to determine that defendants' actions were illegal and that the defendants have a duty to notify all victims and to provide them with health care. In the suit, 654:. Existing documentation admits only that the substance was tested at Edgewood Arsenal, and all other data, including the medical records from the subjects are completely missing. Because of the extremely limited data, speculation on possible side effects from exposure is impossible. 774:
more for incapacitating effects to show, and the end-effects usually did not include full incapacitation, let alone unconsciousness. After all, the Edgewood experimenters were focused on disabling soldiers in combat, where there would be tactical value simply in disabling the enemy.
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Urban, Jonathan D.; Clarke, William P.; von Zastrow, Mark; Nichols, David E.; Kobilka, Brian; Weinstein, Harel; Javitch, Jonathan A.; Roth, Bryan L.; Christopoulos, Arthur; Sexton, Patrick M.; Miller, Keith J.; Spedding, Michael; Mailman, Richard B. (January 2007).
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as so called "toxicological warfare agents". He went on to suggest that with intensive research, substances that depleted certain necessary nutrients could be found, which would, when administered on the battlefield, incapacitate enemy combatants.
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mentioned above, is that they "did not detect any significant long-term health effects on the Edgewood Arsenal volunteers". The safety record of the Edgewood Arsenal experiments was also defended in the memoirs of psychiatrist and retired colonel
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appointed a so-called Ad Hoc Study Group on Psychochemical Agents, which seems to have acted as a central authority on the research of psychochemical at Edgewood Arsenal and other installations where such experimentation occurred.
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The U.S. Army believed that legal liability could be avoided by concealing the experiments. However once the experiments were uncovered, the US Senate also concluded questionable legality of the experiments and strongly condemned
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volume in the main experimental documentation. Much of the follow up data on the acetylcholine related experiments are lacking or entirely missing, due to a combination of remaining classification and failures on the part of the
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As late as 2014, information was incomplete; IOM could not conduct adequate medical studies related to similar former US biowarfare programs, because relevant classified documents had not been declassified and released.
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A failure to secure informed consent and other widespread failures to follow the precepts of U.S. and international law regarding the use of human subjects, including the 1953 Wilson Directive and the Nuremberg
1988: 1836: 289:), including human subject experiments and the debriefing of former Nazi physicians and scientists who had worked along similar lines before the end of the war. In the 1950s, some officials in the 2936:
Holze, Friederike; Vizeli, Patrick; Ley, Laura; Müller, Felix; Dolder, Patrick; Stocker, Melanie; Duthaler, Urs; Varghese, Nimmy; Eckert, Anne; Borgwardt, Stefan; Liechti, Matthias E. (Feb 2021).
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In September 1975, the Medical Research Volunteer Program was discontinued and all resident volunteers were removed from the Edgewood installation. The founder and director of the program,
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A deliberate destruction of evidence and files documenting their illegal actions, actions which were punctuated by fraud, deception, and a callous disregard for the value of human life.
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young soldiers chosen at random might be expected to expire during any one-year period. By this logic, Edgewood was possibly the safest military place in the world to spend two months.
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decades since their introduction to medical use, research has begun to suggest a causal relationship between long term anticholinergic drug use and later development or worsening of
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Dmochowski, Roger R.; Thai, Sydney; Iglay, Kristy; Enemchukwu, Ekene; Tee, Silvia; Varano, Susann; Girman, Cynthia; Radican, Larry; Mudd, Paul N.; Poole, Charles (January 2021).
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agreed to take on a class-action lawsuit against the government related to the Edgewood volunteers. The plaintiffs collectively referred to themselves as the "Test Vets".
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Chemical Warfare: Secrets Almost Forgotten, A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War (1955–1975)
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Chemical Warfare Secrets Almost Forgotten, A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War (1955–1975)
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in 1959 that "provided sufficient emphasis is put behind it, I think the future lies in the psychochemicals." This was alarming enough to a Harvard psychiatrist,
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According to a DOD FAQ, the Edgewood Arsenal experiments involved the following "rough breakout of volunteer hours against various experimental categories":
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subject that it has been the subject of insufficient research to conclude this beyond a reasonable doubt. In total, 219 subjects were tested with 4 agents.
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The LSD experiments are perhaps the best documented of the psychochemical experiments of the time, garnering at least two significant independent reports.
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made for release of multiple films made of Project SHAD tests. None of the requested materials were cleared for public release as of this writing (2016).
4099: 310: 3105: 1519:, from Edgewood Arsenal, who explained how the experiments there were about searching for humane weapons, adding that the use of LSD was unacceptable. 520:, genetic mutation and cancer. In total, 1,406 subjects were tested with 16 agents, some of which included reactivating agents and protective agents. 70:, and continued until the public became aware of the experiments, resulting in significant outcry. The purpose was to evaluate the impact of low-dose 295: 4269: 663: 4224: 3588: 2756:"Distinct temporal phases in the behavioral pharmacology of LSD: dopamine D2 receptor-mediated effects in the rat and implications for psychosis" 1516: 3634: 2009: 1820: 3690: 862:
A refusal to satisfy their legal and moral obligations to locate the victims of experiments or to provide health care or compensation to them
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that would create the same debilitating mental side effects as those produced by nerve gases, but without their lethal effect. In his words,
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Overall, about 6,720 soldiers took part in these experiments that involved exposures to more than 250 different chemicals, according to the
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List of notable CS (Chemical Structure) and CAS (Chemical Abstracts Service) numbered chemicals used in the Edgewood Arsenal Experiments
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apparent in the CIA's programs are paralleled by a lack of clear authorization and supervision in the Army's programs.(S. Rep., at 411.)
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Greene, L. Wilson, "Psychochemical Warfare: A New Concept of War", U. S. Army Chemical Center, Edgewood Arsenal, Maryland; August 1949.
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Chemical and Biological Defense: DOD Needs to Continue to Collect and Provide Information on Tests and Potentially Exposed Personnel
4120: 4092: 3710: 3358: 2466:"Protection of Human Red Cell Cholinesterase Against Inhibition by Tabun and O,O-Diethyl-S-2-Diethylaminoethyl Phosphorothiolate" 3613: 3597: 2331:"Increased risk of incident dementia following use of anticholinergic agents: A systematic literature review and meta-analysis" 1948:. United States Department of Defense, Force Health Protection & Readiness, Medical Countermeasures website. Archived from 1532:. Hunt used this finding to assert that in this collaboration, US and former Nazi scientists "used Nazi science as a basis for 1421: 43:'Effects of Lysergic Acid Diethylamide (LSD) on Troops Marching' - 16mm film produced by the United States military circa 1958. 3077: 3059: 2269: 2227: 2088: 1926: 1898: 1481: 323: 294:
field were cited as a special incentive giving impetus to research efforts in this area, according to testimony by Maj. Gen.
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Colovic, Mirjana B.; Krstic, Danijela Z.; Lazarevic-Pasti, Tamara D.; Bondzic, Aleksandra M.; Vasic, Vesna M. (2013-04-01).
1725: 2938:"Acute dose-dependent effects of lysergic acid diethylamide in a double-blind placebo-controlled study in healthy subjects" 1736: 3462: 1480:, ChemBook, Inc., 360 pp, was written by Ketchum who was a key player after 1960 and went on to become a professor at the 901: 3623: 3581: 2208:"Organization and Electrophysiology of Interstitial Cells of Cajal and Smooth Muscle Cells in the Gastrointestinal Tract" 1426: 799: 463: 302: 245: 98: 2834: 1811: 4259: 4202: 4125: 4085: 2873: 555:. In total, 1,752 subjects were tested with 21 agents, some of whom received exposure to more than one chemical agent. 2427:"Formation of potent inhibitors of AChE by reaction of pyridinaldoximes with isopropyl methylphosphonofluoridate (GB)" 4130: 4015: 855:
The use of troops to test nerve gas, psychochemicals, and thousands of other toxic chemical or biological substances.
3436: 1969: 1772: 1470:, who went on to become a prof of psychiatry at Yale. Bowers' book is a "fictionalized" account with names changed. 1247: 1087:- A "V-series" nerve agent, Cyclopentyl S-2-diethylaminoethyl methylphosphonothiolate ("Substance 100A" to Soviets) 3522: 1889:
Malcolm Dando; Martin Furmanski (2006). "Midspectrum Incapacitant Programs". In Mark Wheelis; Lajos Rózsa (eds.).
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Two autobiographical books from psychiatrists conducting human experiments at Edgewood have been self-published:
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Breeding Bio Insecurity: How U.S. Biodefense Is Exporting Fear, Globalizing Risk, and Making Us All Less Secure
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Breeding Bio Insecurity: How U.S. Biodefense Is Exporting Fear, Globalizing Risk, and Making Us All Less Secure
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as having been used in the Edgewood Arsenal Experiments, though they did not receive an EA number designation.
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Even a book critical of the program, written by Lynn C. Klotz and Edward J. Sylvester, acknowledges that:
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took place from approximately 1948 to 1975 at the Medical Research Laboratories—which is now known as the
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Edgewood Arsenal Chemical Agent Exposure Studies FAQs. What types of tests were conducted at Edgewood?
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before the Committee on Science and Astronautics, U.S. House of Representatives, June 1959 (No. 22).
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The official position of the Department of Defense, based on the three-volume set of studies by the
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A classified report entitled "Psychochemical Warfare: A New Concept of War" was produced in 1949 by
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In 1947, the first steps of planning began when Dr. Alsoph H. Corwin, a professor of chemistry at
3984: 3715: 2387: 349: 345: 2898: 4025: 3979: 3949: 3909: 3904: 3899: 3695: 3675: 3541: 3385:"Operation Delirium: Decades after a risky Cold War experiment, a scientist lives with secrets" 1259: 1163: 829: 643: 532: 478: 91: 55: 52: 3015: 1631: 547:
to the extreme. This can result in anticholinergic syndrome, and possibly death if untreated.
4254: 4156: 4056: 3974: 3964: 3705: 3670: 3279: 1845: 1490: 1381: 1240: 742: 684: 513: 348:, Maryland. The experiments involved at least 254 chemical substances, but focused mainly on 261: 146: 3021: 2153:"EEG, PSYCHOLOGICAL, AND NEUROLOGICAL ALTERATIONS IN HUMANS WITH ORGANOPHOSPHORUS EXPOSURE*" 1637: 1547:
Two TV documentaries, with different content but confusingly similar titles were broadcast:
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Hunt, Secret Agenda: The U.S. Government, Nazi Scientists and Project Paperclip 1945-1991.
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Sánchez-Pastor, Enrique; Trujillo, Xóchitl; Huerta, Miguel; Andrade, Felipa (2007-01-31).
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enemy without the wholesale killing of his people or the mass destruction of his property.
8: 4151: 3959: 3807: 3660: 3566: 2975: 2850: 2121: 1563: 1314: 1216: 1203: 1062: 934: 701:
Vol. 2, "Cholinesterase Reactivators, Psychochemicals and Irritants and Vesicants" (1984)
214: 79: 2249: 2207: 2168: 2152: 4051: 3826: 3802: 2976:"Measured average height, weight, and waist circumference for adults ages 20 and older" 2874:"A woman took 550 times the usual dose of LSD, with surprisingly positive consequences" 2363: 2330: 2261: 2219: 2176: 2056: 1464:
Men and Poisons: The Edgewood Volunteers and the Army Chemical Warfare Research Program
1416: 571: 509: 502: 474: 75: 3954: 3939: 3812: 3745: 3560: 3295: 3269:, Operation Paperclip, 1991, and hearings before the House Judiciary Committee, 1991. 3073: 3055: 2957: 2937: 2918: 2914: 2854: 2815: 2775: 2755: 2678: 2670: 2632:"TNAA Atropine and Pralidoxime Chloride Auto-Injector – Full Prescribing Information" 2610: 2606: 2571: 2532: 2524: 2505:"Effects of Cannabinoids on Synaptic Transmission in the Frog Neuromuscular Junction" 2485: 2446: 2442: 2407: 2368: 2350: 2311: 2265: 2223: 2188: 2180: 2133: 2125: 2084: 2061: 2043: 1922: 1894: 1752: 1529: 1477: 1270: 1167: 517: 273:
In the late 1940s and early '50s, the U.S. Army worked with Harvard anesthesiologist
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Health Outcomes Among Veterans of Project SHAD (Shipboard Hazard and Defense) (2016)
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Television News Archive has two videos about the experiments, both from a July 1975
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Secret Agenda: the United States Government, Nazi Scientists and Project Paperclip
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Vol. 2, "Cholinesterase Reactivators, Psychochemicals and Irritants and Vesicants
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Vol. 2, "Cholinesterase Reactivators, Psychochemicals and Irritants and Vesicants
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tested on volunteers included chemical warfare agents and other related agents:
4030: 3618: 3527: 3206: 3179: 2953: 2736:. U.S. Army Medical Department, U.S. Army Health Services Command. October 1980 1390: 494: 233: 185: 152: 3122: 2771: 4218: 3856: 3760: 2961: 2922: 2858: 2819: 2779: 2674: 2614: 2575: 2528: 2504: 2489: 2450: 2354: 2315: 2291: 2184: 2129: 2047: 2023: 1808: 1554: 1411: 1299: 1209: 1050: 687:(IOM) published a three-volume report on the Edgewood research in 1982–1985, 651: 616: 540: 490: 162: 4077: 2811: 2796:"Functional Selectivity and Classical Concepts of Quantitative Pharmacology" 2520: 2307: 1809:"Altered States: LSD and the Anesthesia Laboratory of Henry Knowles Beecher" 1653:"War Related Illness and Injury Study Center: Edgewood-Aberdeen Experiments" 3969: 3929: 3924: 3919: 3914: 3755: 3178:
CHEMICAL RESEARCH AND DEVELOPMENT LABS EDGEWOOD ARSENAL MD (July 1, 1964).
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Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents
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Marona-Lewicka, Danuta; Thisted, Ronald A.; Nichols, David E. (July 2005).
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Naunyn-Schmiedebergs Archiv for Experimentelle Pathologie und Pharmakologie
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Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents
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Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents
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Effects of drugs and environmental stress on human physiological mechanisms
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Vietnam Veterans of America, et al. v. Central Intelligence Agency, et al.
3486:"Secret Army volunteer's widow blames VA for spouse's death" (CNN; 3/3/12) 3125:
Vietnam Veterans of America, et al. v. Central Intelligence Agency, et al.
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Voicu, Victor; Rădulescu, Flavian Ştefan; Medvedovici, Andrei (Jan 2013).
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Vietnam Veterans of America, et al. v. Central Intelligence Agency, et al.
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In 2012, the Edgewood/Aberdeen experiments were featured on CNN and in
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Former sergeant seeks compensation for LSD testing at Edgewood Arsenal
2346: 4020: 3989: 3934: 3341: 3180:"THE HUMAN ASSESSMENT OF EA 1729 AND EA 3528 BY THE INHALATION ROUTE" 2465: 1320: 1275: 704:
Vol. 3, "Final Report: Current Health Status of Test Subjects" (1985)
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an acetylcholinesterase inhibitor and indirect cholinergic agonist (
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Technical Command positing the potential for the use of specialized
3994: 3851: 3840: 3507: 2651:"Toxicological considerations of acetylcholinesterase reactivators" 2502: 2021: 1219: 620: 552: 189: 142: 138: 63: 1528:, revealed that eight German scientists worked at Edgewood, under 4066: 3640:
Program Executive Office, Assembled Chemical Weapons Alternatives
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Vol. 3, "Final Report: Current Health Status of Test Subjects"
2024:"Acetylcholinesterase Inhibitors: Pharmacology and Toxicology" 1638:
Vol. 3, "Final Report: Current Health Status of Test Subjects"
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Heilbronn, E.; Appelgren, I.-E.; Sundwall, A. (August 1964).
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Eight individual isomers numbered EA-2233-1 through EA-2233-8
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In 2009 a lawsuit was filed by veterans rights organizations
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Materson, Barry J.; Barrett-Connor, Elizabeth (1967-06-19).
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Marx, John A.; Hockberger, Robert S.; Walls, Ron M. (2010),
1946:"Edgewood Arsenal Chemical Agent Exposure Studies 1955–1975" 209:, U.S. military researchers obtained formulas for the three 3106:"United States v. Stanley, 483 US 669 - Supreme Court 1987" 2425:
Hackley, B.E.; Steinberg, G.M.; Lamb, J.C. (January 1959).
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Rosen's Emergency Medicine – Concepts and Clinical Practice
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Bethe, K.; Erdmann, W.D.; Lendle, L.; Schmidt, G. (1957).
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Jokanović, Milan; Stojiljković, Miloš P. (December 2006).
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Vietnam Veterans of America v. Central Intelligence Agency
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Vol. 1, "Anticholinesterases and Anticholinergics" (1982).
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Sanders, Kenton M.; Koh, Sang Don; Ward, Sean M. (2012),
1858:"Chemical, Biological, and Radiological Warfare Agents", 1336: 1189:
National Academies of Sciences, Engineering, and Medicine
1106: 1026: 1002: 600: 588: 558: 357: 353: 286: 158: 27:(a similar military program) undertaken at the same time. 3629:
U.S. Army Medical Research Institute of Chemical Defense
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List of notable EA (Edgewood Arsenal) numbered chemicals
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U.S. Army Medical Research Institute of Chemical Defense
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Nerve agent reactivators, e.g. the common OP antidote
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Journal of Pharmacology and Experimental Therapeutics
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Journal of Pharmacology and Experimental Therapeutics
2385: 1912: 1910: 581: 4062:
Unethical human experimentation in the United States
2935: 2424: 2081:
Current therapy of trauma and surgical critical care
452: 435:
Human factors tests (ability to follow instructions)
90:. A small portion of these studies were directed at 2247: 1739:
Office of the Inspector General and Auditor General
1466:(2005), Xlibris Corporation, 140pp, was written by 4245:20th-century military history of the United States 3127:Case No. CV-09-0037-CW, U.S.D.C. (N.D. Cal. 2009)" 3010:Vol. 1, "Anticholinesterases and Anticholinergics" 2655:Expert Opinion on Drug Metabolism & Toxicology 2151:Metcalf, David R.; Holmes, Joseph H. (June 1969). 2079:Asenio, Juan A.; Trunkey, Donald D., eds. (2016). 1907: 1626:Vol. 1, "Anticholinesterases and Anticholinergics" 260:at Edgewood. Greene called for a search for novel 66:. These experiments began after the conclusion of 3542:Vets feel abandoned after secret drug experiments 3512:Case No. CV-09-0037-CW, U.S.D.C. (N.D. Cal. 2009) 469: 281:in Germany on the use of psychoactive compounds ( 4216: 3067: 3040:, Government Accounting Office, May 2004, p. 24. 1882: 642:, or BZ is a substance that interferes with the 623:, and a wide variety of physiological symptoms. 3117: 3115: 2470:Canadian Journal of Biochemistry and Physiology 1536:-like experiments on over 7,000 U.S. soldiers". 1524:Journalist Linda Hunt, citing records from the 1352:mixture, related to the chemical warfare agent 1187:The following chemicals were identified by the 466:to follow the subjects of the experimentation. 443:Other (visual studies, sleep deprivation, etc.) 4235:History of the government of the United States 3231: 3204: 3198: 3072:. Santa Rosa, CA: ChemBooks Inc. p. 128. 2205: 1970:Researchers tested pot, LSD on Army volunteers 1893:. Harvard University Press. pp. 245–246. 1891:Deadly Cultures: Biological Weapons since 1945 523: 4107: 4093: 3691:Johnston Atoll Chemical Agent Disposal System 3624:U.S. Army Edgewood Chemical Biological Center 3582: 3514:, Morrison & Foerster LLP, August 7, 2013 2150: 2078: 1723: 3331:. 2 September 1994 – via www.imdb.com. 3112: 1661:United States Department of Veterans Affairs 460:United States Department of Veterans Affairs 4240:Human subject research in the United States 3461:Khatchadourian, Raffi (December 11, 2012). 3435:Khatchadourian, Raffi (December 12, 2012). 3409:Khatchadourian, Raffi (December 16, 2012). 3383:Khatchadourian, Raffi (December 17, 2012). 3357:Khatchadourian, Raffi (December 26, 2012). 3342:Liddell Hart Centre for Military Archives. 3145: 3054:. University of Chicago Press. p. 33. 3050:Lynn C. Klotz; Edward J. Sylvester (2009). 1921:. University of Chicago Press. p. 33. 1917:Lynn C. Klotz; Edward J. Sylvester (2009). 1298:, a synthetic choline ester that acts as a 798: with: older lawsuits. You can help by 200: 4100: 4086: 3589: 3575: 3232:Khatchadourian, Raffi (10 December 2012). 2899:"LSD "Mainlining": A New Hazard to Health" 2832: 2157:Annals of the New York Academy of Sciences 1432:Human experimentation in the United States 877:, a panel majority held in July 2015 that 657: 419:Development evaluation and test procedures 3133:. Morrison & Foerster. August 7, 2013 2362: 2055: 3251:"July 17, 1975 NBC Evening News segment" 3171: 2835:"Long Lasting Effects of LSD on Normals" 2212:Physiology of the Gastrointestinal Tract 2083:(2nd ed.). Philadelphia: Elsevier. 29: 4270:Cannabis and the United States military 3711:Tooele Chemical Agent Disposal Facility 3253:, Vanderbilt University, July 17, 1975. 2431:Archives of Biochemistry and Biophysics 2008:was invoked but never defined (see the 980:, an analogue and active metabolite of 531:are substances that interfere with the 489:and therefore sustaining the effect of 477:are substances that interfere with the 4225:Central Intelligence Agency operations 4217: 3598:United States chemical weapons program 3213:. Defense Technical Information Center 3186:. Defense Technical Information Center 2463: 2289: 2103: 1940: 1938: 1476:(2006, 2nd edition 2007), foreword by 1422:United States chemical weapons program 848:biological agent testing experiments. 607:that acts as a dopamine and serotonin 559:Cholinesterase Reactivator Experiments 508:Long term side effects of exposure to 258:Chemical and Radiological Laboratories 4081: 3635:U.S. Army Chemical Materials Activity 3570: 3537:, U.S. Department of Veterans Affairs 3359:"Primary Sources: Operation Delirium" 3312: 2724: 2722: 2720: 2700: 2698: 2696: 2694: 2692: 2638:. Meridian Medical Technologies, LLC. 2626: 2624: 1611: 1482:University of California, Los Angeles 674: 324:The Bulletin of the Atomic Scientists 298:, the Army's chief chemical officer. 16:US military chemical warfare research 3205:Johnson, Kelli (February 29, 2016). 2871: 2851:10.1001/archpsyc.1967.01730290009002 2711:Defense Technical Information Center 2122:10.1001/archneur.1978.00500320050011 1737:United States Department of the Army 1719: 1717: 1715: 1713: 1711: 1709: 1707: 1705: 1678: 1676: 1609: 1607: 1605: 1603: 1601: 1599: 1597: 1595: 1593: 1591: 888: 782: 3411:"High Anxiety: LSD in the Cold War" 3002:, Commission on Life Sciences. The 2707:"Clinical Investigation of EA 1729" 2704: 2003: 1935: 1688:VA Public Health Military Exposures 1618:, Commission on Life Sciences. The 1427:Edgewood Chemical Biological Center 930:- Diisopropyl fluorophosphate (DFP) 505:, and possibly death if untreated. 464:United States Department of Defense 303:United States Department of Defense 246:Edgewood Chemical Biological Center 13: 4147:Edgewood Arsenal human experiments 3741:Edgewood Arsenal human experiments 2968: 2833:McGlothlin, William (1967-11-01). 2717: 2689: 2621: 2262:10.1016/b978-0-323-05472-0.00205-x 2220:10.1016/b978-0-12-382026-6.00018-x 2177:10.1111/j.1749-6632.1969.tb15857.x 1998: 1454: 594: 582:Psychochemical Related Experiments 338:Edgewood Arsenal human experiments 331: 14: 4281: 3501: 3281:Bulletin of the Atomic Scientists 1877:Bulletin of the Atomic Scientists 1702: 1684:"Edgewood / Aberdeen Experiments" 1673: 1588: 978:- Methylenedioxyamphetamine (MDA) 970:- Tetraethyl pyrophosphate (TEPP) 736: 634: 570:which has been inactivated by an 453:Acetylcholine Related Experiments 411:Protective equipment and clothing 344:(USAMRICD)—at the Edgewood Area, 112:Anticholinesterase nerve agents ( 4198: 4197: 2915:10.1001/jama.1967.03120250160025 2392:European Journal of Pharmacology 2290:Wilson, T. R. (September 1973). 2004:Cite error: The named reference 1724:Taylor, JR; Johnson, WN (1976). 1248:nicotinic acetylcholine receptor 892: 786: 566:are substances which reactivate 3489: 3480: 3454: 3428: 3402: 3376: 3350: 3335: 3321: 3306: 3288: 3272: 3256: 3244: 3225: 3098: 3086: 3043: 3037:Chemical and Biological Defense 3029: 2993: 2929: 2890: 2865: 2826: 2786: 2747: 2642: 2582: 2543: 2496: 2457: 2418: 2379: 2322: 2283: 2241: 2199: 2144: 2097: 2072: 2015: 1979: 1963: 1865: 1834:"US Plans Study of Gas Warfare" 1145:- Etonitazene in free base form 277:at its interrogation center at 3240:– via www.newyorker.com. 2839:Archives of General Psychiatry 2214:, Elsevier, pp. 511–556, 2104:Morgan, John P. (1978-08-01). 1852: 1827: 1801: 1792: 1765: 1645: 1283:acetylcholinesterase inhibitor 1267:acetylcholinesterase inhibitor 1236:acetylcholinesterase inhibitor 470:Anticholinesterase Experiments 380:Percentage of volunteer hours 157:Psychoactive agents including 1: 3535:Edgewood/Aberdeen Experiments 3346:– via Internet Archive. 3344:"Bad Trip To Edgewood (1993)" 3317:– via Internet Archive. 3284:. September 1992. p. 43. 2296:British Journal of Psychiatry 1449: 1222:, specifically, a reversible 315:U.S. House of Representatives 3798:Operation Davy Jones' Locker 3701:Pine Bluff Chemical Activity 2730:"LSD follow-up study report" 2667:10.1517/17425255.2013.736489 2607:10.1016/0006-2952(64)90120-0 2464:Scaife, J. F. (1960-03-01). 2443:10.1016/0003-9861(59)90359-5 2404:10.1016/j.ejphar.2006.09.054 2335:Neurourology and Urodynamics 1873:"Psychochemicals as Weapons" 1871:Lieberman, E. James (1962), 1657:www.warrelatedillness.va.gov 1582: 1133:- An enantiomer of the drug 721:Government Accounting Office 710:National Academy of Sciences 669: 256:, Technical Director of the 7: 4182:Marijuana Smoking in Panama 3846:Methylphosphonyl difluoride 3315:"A Bad Trip to Edgewood #1" 2040:10.2174/1570159x11311030006 1405: 1378:- Methylscopolamine bromide 1303:muscarinic receptor agonist 1137:, also known as benzetimide 1079:("Substance 78" to Soviets) 837:Vietnam Veterans of America 828:In the 1990s, the law firm 778: 564:Cholinesterase Reactivators 524:Anticholinergic Experiments 23:(a similar CIA program) or 10: 4286: 3681:Edgewood Chemical Activity 3666:Anniston Chemical Activity 3265:St. Martin's Press, 1991; 2954:10.1038/s41386-020-00883-6 2872:Hunt, Katie (2020-02-27). 2106:"Jamaica Ginger Paralysis" 1807:George A. Mashour (2009), 1757:: CS1 maint: url-status ( 1515:reported on Major General 727:(pp. 1, 24), stated: 291:U.S. Department of Defense 249:treatment and prevention. 195: 18: 4260:Psychedelic drug research 4192: 4165: 4139: 4113: 4108:Cannabis and the military 4044: 4008: 3882: 3835:3-Quinuclidinyl benzilate 3825: 3785: 3769: 3733: 3724: 3653: 3645:Chemical mortar battalion 3604: 3068:James S. Ketchum (2006). 2772:10.1007/s00213-005-2183-9 2705:Sim, Van M. (June 1961). 2028:Current Neuropharmacology 1843:, Sunday, 9 August 1959, 1824:, Winter issue, pp 68-74. 1354:3-Quinuclidinyl benzilate 648:Peripheral nervous system 640:3-Quinuclidinyl benzilate 537:Peripheral nervous system 483:Peripheral nervous system 350:midspectrum incapacitants 3619:U.S. Army Chemical Corps 3095:National Academies Press 3004:National Academies Press 2595:Biochemical Pharmacology 2256:, Elsevier, pp. v, 1778:Johns Hopkins University 1620:National Academies Press 1443:United States v. Stanley 1263:- Pyridostigmine bromide 1224:cholinesterase inhibitor 694:The three volumes were: 545:cholinesterase inhibitor 386:Incapacitating compounds 230:Johns Hopkins University 205:After the conclusion of 201:Background and rationale 49:U.S. Army Chemical Corps 19:Not to be confused with 3985:XM736 8-inch projectile 3716:Umatilla Chemical Depot 3463:"Manufacturing Madness" 2942:Neuropsychopharmacology 2812:10.1124/jpet.106.104463 2521:10.1124/jpet.106.116319 2308:10.1192/bjp.123.3.366-a 1468:Malcolm Baker Bowers Jr 1244:- Hexafluronium bromide 1030:- LSD in free base form 830:Morrison & Foerster 658:Scandal and termination 346:Aberdeen Proving Ground 213:developed by the Nazis— 47:From 1948 to 1975, the 3980:M687 155 mm projectile 3950:M360 105 mm projectile 3910:M121 155 mm projectile 3905:M110 155 mm projectile 3900:M104 155 mm projectile 3696:Newport Chemical Depot 3676:Deseret Chemical Depot 3614:2nd Chemical Battalion 3607:centers and institutes 3329:"Bad Trip to Edgewood" 1526:U.S. National Archives 1006:- LSD in tartrate form 851:The plaintiffs cited: 826: 776: 767: 757: 734: 644:Central nervous system 533:Central nervous system 479:Central nervous system 403:Riot control compounds 271: 262:psychoactive compounds 92:psychochemical warfare 56:human subject research 44: 4157:Operation Green Sweep 4057:Dugway sheep incident 3975:M60 105 mm projectile 3965:M44 generator cluster 3706:Pueblo Chemical Depot 3671:Blue Grass Army Depot 3654:Industrial facilities 2110:Archives of Neurology 1846:The Milwaukee Journal 1567:Investigative Reports 1491:Vanderbilt University 1382:muscarinic antagonist 1110:- LSD in maleate form 1054:- Phencyclidine (PCP) 879:Army Regulation 70-25 821: 771: 762: 752: 743:Institute of Medicine 729: 685:Institute of Medicine 514:peripheral neuropathy 377:Experimental category 328:afflictions of war." 266: 244:In 1948, the US Army 99:Department of Defense 42: 4009:Protective equipment 3890:BLU-80/B Bigeye bomb 3777:Operation Ranch Hand 3686:Hawthorne Army Depot 3544:, CNN, March 1, 2012 3508:Edgewood Test Vets: 3313:Yorkshire, I. T. V. 3234:"Operation Delirium" 3006:. In three volumes: 2636:FDALabel Version 2.9 1622:. In three volumes: 1560:Bad Trip to Edgewood 1551:Bad Trip to Edgewood 1437:Swords to Plowshares 1350:anticholinergic drug 1333:anticholinergic drug 906:adding missing items 841:Swords to Plowshares 723:report of May 2004, 568:acetylcholinesterase 487:acetylcholinesterase 254:Luther Wilson Greene 4250:Military psychiatry 4152:Night Train Seizure 3960:M43 BZ cluster bomb 3808:Operation Steel Box 3661:Anniston Army Depot 3531:, December 26, 2012 3523:Secrets of Edgewood 2169:1969NYASA.160..357M 1733:GovernmentAttic.org 1541:The Washington Post 1315:parasympathomimetic 1217:parasympathomimetic 1204:parasympathomimetic 1063:dimethylheptylpyran 750:, a key scientist: 615:effect, leading to 510:Anticholinesterases 475:Anticholinesterases 80:protective clothing 4052:CB military symbol 3803:Operation Geranium 3605:Units, formations, 3554:2015-04-06 at the 3267:ABC PrimeTime Live 3131:Edgewood Test Vets 2760:Psychopharmacology 2568:10.1007/bf00246123 1995:September 08, 2008 1991:2015-06-21 at the 1839:2020-01-26 at the 1814:2015-03-19 at the 1417:CB military symbol 904:; you can help by 680:1982-85 IOM report 675:Government reports 572:anticholinesterase 503:cholinergic crisis 319:E. James Lieberman 301:In June 1955, the 76:military personnel 45: 4265:Cannabis research 4212: 4211: 4075: 4074: 3955:M426 8-inch shell 3940:M23 chemical mine 3821: 3820: 3813:Operation Red Hat 3746:Operation Top Hat 3561:The Baltimore Sun 3558:, July 11, 1991, 3540:David S. Martin, 3437:"War of the Mind" 3079:978-1-4243-0080-8 3061:978-0-226-44407-9 2909:(12): 1126–1127. 2347:10.1002/nau.24536 2271:978-0-323-05472-0 2229:978-0-12-382026-6 2090:978-0-323-07980-8 1972:Richard Willing, 1928:978-0-226-44407-9 1900:978-0-674-04513-2 1530:Project Paperclip 1478:Alexander Shulgin 1271:Gulf War syndrome 1168:isopropyl alcohol 1166:from mixing OPA ( 962:- Cyclosarin (GF) 922: 921: 816: 815: 518:sleep disturbance 501:, resulting in a 499:chemical synapses 450: 449: 311:William M. Creasy 40: 4277: 4230:Chemical warfare 4201: 4200: 4174:Hemp for Victory 4102: 4095: 4088: 4079: 4078: 3945:M34 cluster bomb 3895:M1 chemical mine 3731: 3730: 3591: 3584: 3577: 3568: 3567: 3496: 3493: 3487: 3484: 3478: 3477: 3475: 3473: 3458: 3452: 3451: 3449: 3447: 3432: 3426: 3425: 3423: 3421: 3406: 3400: 3399: 3397: 3395: 3380: 3374: 3373: 3371: 3369: 3354: 3348: 3347: 3339: 3333: 3332: 3325: 3319: 3318: 3310: 3304: 3303: 3292: 3286: 3285: 3276: 3270: 3260: 3254: 3248: 3242: 3241: 3229: 3223: 3222: 3220: 3218: 3202: 3196: 3195: 3193: 3191: 3175: 3169: 3168: 3166: 3164: 3149: 3143: 3142: 3140: 3138: 3119: 3110: 3109: 3102: 3096: 3090: 3084: 3083: 3065: 3047: 3041: 3033: 3027: 2997: 2991: 2990: 2988: 2987: 2972: 2966: 2965: 2933: 2927: 2926: 2894: 2888: 2887: 2885: 2884: 2869: 2863: 2862: 2830: 2824: 2823: 2790: 2784: 2783: 2751: 2745: 2744: 2742: 2741: 2726: 2715: 2714: 2702: 2687: 2686: 2646: 2640: 2639: 2628: 2619: 2618: 2601:(8): 1189–1195. 2586: 2580: 2579: 2547: 2541: 2540: 2500: 2494: 2493: 2461: 2455: 2454: 2422: 2416: 2415: 2383: 2377: 2376: 2366: 2326: 2320: 2319: 2302:(574): 366–367. 2287: 2281: 2280: 2279: 2278: 2245: 2239: 2238: 2237: 2236: 2203: 2197: 2196: 2148: 2142: 2141: 2101: 2095: 2094: 2076: 2070: 2069: 2059: 2019: 2013: 2007: 2002: 1996: 1983: 1977: 1967: 1961: 1960: 1958: 1957: 1942: 1933: 1932: 1914: 1905: 1904: 1886: 1880: 1879:(January issue). 1869: 1863: 1856: 1850: 1831: 1825: 1805: 1799: 1796: 1790: 1789: 1787: 1786: 1769: 1763: 1762: 1756: 1748: 1746: 1744: 1730: 1721: 1700: 1699: 1697: 1695: 1680: 1671: 1670: 1668: 1667: 1649: 1643: 1613: 1506:Norman Augustine 1504:reported on how 1495:NBC Evening News 1394:- Methylatropine 1339:as a truth serum 917: 914: 896: 895: 889: 811: 808: 790: 783: 611:precipitating a 605:Psychedelic drug 529:Anticholinergics 395:Lethal compounds 374: 373: 275:Henry K. Beecher 122:organophosphorus 72:chemical warfare 60:Edgewood Arsenal 41: 4285: 4284: 4280: 4279: 4278: 4276: 4275: 4274: 4215: 4214: 4213: 4208: 4188: 4161: 4135: 4109: 4106: 4076: 4071: 4040: 4004: 3878: 3817: 3793:Operation CHASE 3781: 3765: 3726: 3720: 3649: 3606: 3600: 3595: 3556:Wayback Machine 3504: 3499: 3494: 3490: 3485: 3481: 3471: 3469: 3459: 3455: 3445: 3443: 3433: 3429: 3419: 3417: 3407: 3403: 3393: 3391: 3381: 3377: 3367: 3365: 3355: 3351: 3340: 3336: 3327: 3326: 3322: 3311: 3307: 3294: 3293: 3289: 3278: 3277: 3273: 3261: 3257: 3249: 3245: 3230: 3226: 3216: 3214: 3203: 3199: 3189: 3187: 3176: 3172: 3162: 3160: 3159:. 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1455:General sources 1452: 1408: 1403: 1335:studied by the 1287:organophosphate 1215:a highly toxic 1185: 1180: 1172:isopropyl amine 918: 912: 909: 893: 887: 812: 806: 803: 796:needs expansion 781: 739: 718: 716:2004 GAO report 682: 677: 672: 660: 637: 597: 595:LSD Experiments 584: 561: 526: 472: 455: 362:benzodiazepines 334: 332:The experiments 296:Marshall Stubbs 203: 198: 106:chemical agents 84:pharmaceuticals 30: 28: 21:Project MKUltra 17: 12: 11: 5: 4283: 4273: 4272: 4267: 4262: 4257: 4252: 4247: 4242: 4237: 4232: 4227: 4210: 4209: 4207: 4206: 4193: 4190: 4189: 4187: 4186: 4178: 4169: 4167: 4163: 4162: 4160: 4159: 4154: 4149: 4143: 4141: 4137: 4136: 4134: 4133: 4128: 4123: 4117: 4115: 4111: 4110: 4105: 4104: 4097: 4090: 4082: 4073: 4072: 4070: 4069: 4064: 4059: 4054: 4048: 4046: 4045:Related topics 4042: 4041: 4039: 4038: 4033: 4031:People sniffer 4028: 4023: 4018: 4012: 4010: 4006: 4005: 4003: 4002: 3997: 3992: 3987: 3982: 3977: 3972: 3967: 3962: 3957: 3952: 3947: 3942: 3937: 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2766:(3): 427–435. 2746: 2716: 2688: 2641: 2620: 2581: 2542: 2515:(2): 439–445. 2495: 2476:(3): 301–303. 2456: 2437:(1): 211–214. 2417: 2398:(1–3): 10–17. 2378: 2321: 2282: 2270: 2240: 2228: 2198: 2163:(1): 357–365. 2143: 2116:(8): 530–532. 2096: 2089: 2071: 2034:(3): 315–335. 2014: 1997: 1978: 1962: 1934: 1927: 1906: 1899: 1881: 1864: 1851: 1826: 1800: 1791: 1764: 1701: 1672: 1644: 1642: 1641: 1635: 1629: 1586: 1584: 1581: 1580: 1579: 1576:The New Yorker 1572: 1571: 1570: 1557: 1545: 1537: 1522: 1521: 1520: 1511:Correspondent 1509: 1487: 1486: 1485: 1471: 1456: 1453: 1451: 1448: 1447: 1446: 1439: 1434: 1429: 1424: 1419: 1414: 1407: 1404: 1402: 1401: 1392:CAS 31610-87-4 1388: 1372: 1356: 1340: 1323: 1305: 1296:- Methacholine 1290: 1273: 1269:implicated in 1257: 1238: 1226: 1207: 1193: 1184: 1181: 1179: 1178: 1154: 1146: 1138: 1128: 1127:- A BZ variant 1120: 1119:- A BZ variant 1112: 1104: 1103:- A BZ variant 1096: 1095:- A BZ variant 1088: 1080: 1071: 1070: 1069: 1056: 1048: 1040: 1032: 1024: 1016: 1008: 1000: 992: 984: 972: 964: 956: 948: 940: 932: 923: 920: 919: 899: 897: 886: 883: 867: 866: 863: 860: 856: 814: 813: 793: 791: 780: 777: 738: 737:Safety debates 735: 706: 705: 702: 699: 676: 673: 671: 668: 664:Van Murray Sim 659: 656: 650:by inhibiting 636: 635:BZ Experiments 633: 617:hallucinations 613:hallucinogenic 596: 593: 583: 580: 560: 557: 539:by inhibiting 525: 522: 495:butyrylcholine 485:by inhibiting 471: 468: 454: 451: 448: 447: 444: 440: 439: 436: 432: 431: 428: 424: 423: 420: 416: 415: 412: 408: 407: 404: 400: 399: 396: 392: 391: 388: 382: 381: 378: 333: 330: 234:Chemical Corps 202: 199: 197: 194: 193: 192: 183: 173: 155: 153:2-PAM chloride 149: 135: 129: 15: 9: 6: 4: 3: 2: 4282: 4271: 4268: 4266: 4263: 4261: 4258: 4256: 4253: 4251: 4248: 4246: 4243: 4241: 4238: 4236: 4233: 4231: 4228: 4226: 4223: 4222: 4220: 4205: 4204: 4195: 4194: 4191: 4184: 4183: 4179: 4176: 4175: 4171: 4170: 4168: 4164: 4158: 4155: 4153: 4150: 4148: 4145: 4144: 4142: 4138: 4132: 4129: 4127: 4124: 4122: 4121:United States 4119: 4118: 4116: 4112: 4103: 4098: 4096: 4091: 4089: 4084: 4083: 4080: 4068: 4065: 4063: 4060: 4058: 4055: 4053: 4050: 4049: 4047: 4043: 4037: 4034: 4032: 4029: 4027: 4024: 4022: 4019: 4017: 4014: 4013: 4011: 4007: 4001: 3998: 3996: 3993: 3991: 3988: 3986: 3983: 3981: 3978: 3976: 3973: 3971: 3968: 3966: 3963: 3961: 3958: 3956: 3953: 3951: 3948: 3946: 3943: 3941: 3938: 3936: 3933: 3931: 3928: 3926: 3923: 3921: 3918: 3916: 3913: 3911: 3908: 3906: 3903: 3901: 3898: 3896: 3893: 3891: 3888: 3887: 3885: 3881: 3875: 3872: 3869: 3866: 3863: 3860: 3858: 3855: 3853: 3850: 3847: 3844: 3842: 3839: 3836: 3833: 3832: 3830: 3828: 3824: 3814: 3811: 3809: 3806: 3804: 3801: 3799: 3796: 3794: 3791: 3790: 3788: 3784: 3778: 3775: 3774: 3772: 3768: 3762: 3761:Operation LAC 3759: 3757: 3754: 3752: 3749: 3747: 3744: 3742: 3739: 3738: 3736: 3732: 3729: 3723: 3717: 3714: 3712: 3709: 3707: 3704: 3702: 3699: 3697: 3694: 3692: 3689: 3687: 3684: 3682: 3679: 3677: 3674: 3672: 3669: 3667: 3664: 3662: 3659: 3658: 3656: 3652: 3646: 3643: 3641: 3638: 3636: 3633: 3630: 3627: 3625: 3622: 3620: 3617: 3615: 3612: 3611: 3609: 3603: 3599: 3592: 3587: 3585: 3580: 3578: 3573: 3572: 3569: 3563: 3562: 3557: 3553: 3550: 3546: 3543: 3539: 3536: 3533: 3530: 3529: 3524: 3521: 3519: 3516: 3513: 3511: 3506: 3505: 3492: 3483: 3468: 3464: 3457: 3442: 3438: 3431: 3416: 3412: 3405: 3390: 3386: 3379: 3364: 3360: 3353: 3345: 3338: 3330: 3324: 3316: 3309: 3301: 3300:www.kcl.ac.uk 3297: 3291: 3283: 3282: 3275: 3268: 3264: 3259: 3252: 3247: 3239: 3235: 3228: 3212: 3208: 3201: 3185: 3181: 3174: 3158: 3154: 3148: 3132: 3128: 3126: 3118: 3116: 3107: 3101: 3094: 3089: 3081: 3075: 3071: 3063: 3057: 3053: 3046: 3039: 3038: 3032: 3023: 3020: 3017: 3014: 3011: 3008: 3007: 3005: 3001: 2996: 2981: 2977: 2971: 2963: 2959: 2955: 2951: 2947: 2943: 2939: 2932: 2924: 2920: 2916: 2912: 2908: 2904: 2900: 2893: 2879: 2875: 2868: 2860: 2856: 2852: 2848: 2844: 2840: 2836: 2829: 2821: 2817: 2813: 2809: 2805: 2801: 2797: 2789: 2781: 2777: 2773: 2769: 2765: 2761: 2757: 2750: 2735: 2731: 2725: 2723: 2721: 2712: 2708: 2701: 2699: 2697: 2695: 2693: 2684: 2680: 2676: 2672: 2668: 2664: 2660: 2656: 2652: 2645: 2637: 2633: 2627: 2625: 2616: 2612: 2608: 2604: 2600: 2596: 2592: 2585: 2577: 2573: 2569: 2565: 2561: 2557: 2553: 2546: 2538: 2534: 2530: 2526: 2522: 2518: 2514: 2510: 2506: 2499: 2491: 2487: 2483: 2479: 2475: 2471: 2467: 2460: 2452: 2448: 2444: 2440: 2436: 2432: 2428: 2421: 2413: 2409: 2405: 2401: 2397: 2393: 2389: 2382: 2374: 2370: 2365: 2360: 2356: 2352: 2348: 2344: 2340: 2336: 2332: 2325: 2317: 2313: 2309: 2305: 2301: 2297: 2293: 2286: 2273: 2267: 2263: 2259: 2255: 2251: 2244: 2231: 2225: 2221: 2217: 2213: 2209: 2202: 2194: 2190: 2186: 2182: 2178: 2174: 2170: 2166: 2162: 2158: 2154: 2147: 2139: 2135: 2131: 2127: 2123: 2119: 2115: 2111: 2107: 2100: 2092: 2086: 2082: 2075: 2067: 2063: 2058: 2053: 2049: 2045: 2041: 2037: 2033: 2029: 2025: 2018: 2011: 2001: 1994: 1990: 1987: 1982: 1975: 1971: 1966: 1952:on 2013-07-24 1951: 1947: 1941: 1939: 1930: 1924: 1920: 1913: 1911: 1902: 1896: 1892: 1885: 1878: 1874: 1868: 1861: 1855: 1848: 1847: 1842: 1838: 1835: 1830: 1823: 1822: 1817: 1813: 1810: 1804: 1795: 1780: 1779: 1774: 1768: 1760: 1754: 1743:September 17, 1738: 1734: 1727: 1720: 1718: 1716: 1714: 1712: 1710: 1708: 1706: 1689: 1685: 1679: 1677: 1662: 1658: 1654: 1648: 1639: 1636: 1633: 1630: 1627: 1624: 1623: 1621: 1617: 1612: 1610: 1608: 1606: 1604: 1602: 1600: 1598: 1596: 1594: 1592: 1587: 1577: 1573: 1568: 1565: 1561: 1558: 1556: 1555:ITV Yorkshire 1552: 1549: 1548: 1546: 1542: 1538: 1535: 1531: 1527: 1523: 1518: 1517:Lloyd Fellenz 1514: 1510: 1507: 1503: 1499: 1498: 1496: 1492: 1488: 1483: 1479: 1475: 1472: 1469: 1465: 1462: 1461: 1459: 1458: 1445: 1444: 1440: 1438: 1435: 1433: 1430: 1428: 1425: 1423: 1420: 1418: 1415: 1413: 1412:THC-O-acetate 1410: 1409: 1399: 1395: 1393: 1389: 1386: 1383: 1379: 1377: 1373: 1370: 1367: 1363: 1362:- Hyoscyamine 1361: 1357: 1355: 1351: 1347: 1345: 1344:CAS 8015–54–1 1341: 1338: 1334: 1330: 1329:- Scopolamine 1328: 1324: 1322: 1319: 1316: 1312: 1311:- Bethanechol 1310: 1306: 1304: 1301: 1300:non-selective 1297: 1295: 1291: 1288: 1284: 1280: 1278: 1274: 1272: 1268: 1264: 1262: 1258: 1256: 1252: 1249: 1245: 1243: 1239: 1237: 1233: 1232:- Neostigmine 1231: 1227: 1225: 1221: 1218: 1214: 1212: 1208: 1205: 1201: 1199: 1195: 1194: 1192: 1190: 1177: 1173: 1169: 1165: 1161: 1159: 1155: 1152: 1151: 1147: 1144: 1143: 1139: 1136: 1132: 1129: 1126: 1125: 1121: 1118: 1117: 1113: 1111: 1109: 1105: 1102: 1101: 1097: 1094: 1093: 1089: 1086: 1085: 1081: 1078: 1076: 1072: 1067: 1066: 1064: 1060: 1057: 1055: 1053: 1049: 1047: 1046:- Benactyzine 1045: 1041: 1038: 1037: 1033: 1031: 1029: 1025: 1023: 1021: 1017: 1015: 1013: 1009: 1007: 1005: 1001: 999: 997: 993: 991: 989: 985: 983: 979: 977: 973: 971: 969: 965: 963: 961: 957: 955: 953: 949: 947: 945: 941: 939: 937: 933: 931: 929: 925: 924: 916: 913:February 2015 907: 903: 900:This list is 898: 891: 890: 882: 880: 876: 873:On appeal in 871: 864: 861: 857: 854: 853: 852: 849: 846: 842: 838: 833: 831: 825: 820: 810: 801: 797: 794:This section 792: 789: 785: 784: 775: 770: 766: 761: 756: 751: 749: 748:James Ketchum 744: 733: 728: 726: 722: 717: 713: 711: 703: 700: 697: 696: 695: 692: 690: 686: 681: 667: 665: 655: 653: 652:acetylcholine 649: 645: 641: 632: 628: 624: 622: 618: 614: 610: 606: 602: 592: 590: 579: 575: 573: 569: 565: 556: 554: 548: 546: 542: 541:acetylcholine 538: 534: 530: 521: 519: 515: 511: 506: 504: 500: 496: 492: 491:acetylcholine 488: 484: 480: 476: 467: 465: 461: 445: 442: 441: 437: 434: 433: 429: 426: 425: 421: 418: 417: 413: 410: 409: 405: 402: 401: 397: 394: 393: 389: 387: 384: 383: 379: 376: 375: 372: 369: 367: 363: 360:derivatives, 359: 355: 351: 347: 343: 339: 329: 326: 325: 320: 316: 312: 307: 304: 299: 297: 292: 288: 284: 280: 276: 270: 265: 263: 259: 255: 250: 247: 242: 239: 235: 231: 226: 224: 220: 216: 212: 208: 191: 187: 184: 181: 177: 174: 172: 168: 164: 160: 156: 154: 150: 148: 144: 140: 136: 133: 130: 127: 123: 120:) and common 119: 115: 111: 110: 109: 107: 102: 100: 95: 93: 89: 85: 81: 77: 73: 69: 65: 61: 57: 54: 50: 26: 22: 4255:Mind control 4196: 4180: 4172: 4146: 3930:M139 bomblet 3925:M138 bomblet 3920:M134 bomblet 3915:M125 bomblet 3756:Project SHAD 3740: 3727:and projects 3559: 3547:Tom Bowman, 3526: 3509: 3491: 3482: 3470:. Retrieved 3466: 3456: 3444:. Retrieved 3440: 3430: 3418:. Retrieved 3414: 3404: 3392:. Retrieved 3388: 3378: 3366:. Retrieved 3362: 3352: 3337: 3323: 3308: 3299: 3290: 3280: 3274: 3266: 3262: 3258: 3246: 3237: 3227: 3217:December 19, 3215:. Retrieved 3210: 3200: 3190:December 19, 3188:. Retrieved 3183: 3173: 3161:. Retrieved 3156: 3147: 3135:. Retrieved 3130: 3124: 3100: 3088: 3069: 3051: 3045: 3036: 3031: 2999: 2995: 2984:. Retrieved 2982:. 2023-10-01 2979: 2970: 2945: 2941: 2931: 2906: 2902: 2892: 2881:. Retrieved 2877: 2867: 2842: 2838: 2828: 2803: 2799: 2788: 2763: 2759: 2749: 2738:. Retrieved 2733: 2710: 2661:(1): 31–50. 2658: 2654: 2644: 2635: 2598: 2594: 2584: 2559: 2555: 2545: 2512: 2508: 2498: 2473: 2469: 2459: 2434: 2430: 2420: 2395: 2391: 2381: 2341:(1): 28–37. 2338: 2334: 2324: 2299: 2295: 2285: 2275:, retrieved 2253: 2250:"Dedication" 2243: 2233:, retrieved 2211: 2201: 2160: 2156: 2146: 2113: 2109: 2099: 2080: 2074: 2031: 2027: 2017: 2000: 1981: 1973: 1965: 1954:. Retrieved 1950:the original 1918: 1890: 1884: 1876: 1867: 1859: 1854: 1844: 1829: 1821:CSA Bulletin 1819: 1803: 1794: 1783:. Retrieved 1781:. 2016-07-11 1776: 1767: 1741:. Retrieved 1732: 1692:. Retrieved 1687: 1664:. Retrieved 1656: 1647: 1615: 1575: 1566: 1559: 1550: 1540: 1500:NBC newsman 1494: 1473: 1463: 1441: 1391: 1376:CAS 155–41–9 1375: 1360:CAS 101-31-5 1359: 1343: 1326: 1309:CAS 674-38-4 1308: 1293: 1277:CAS 121–75–5 1276: 1261:CAS 155–97–5 1260: 1242:CAS 317–52–2 1241: 1229: 1210: 1197: 1186: 1164:binary agent 1160:- Sarin (GB) 1157: 1148: 1140: 1130: 1122: 1114: 1107: 1098: 1090: 1082: 1074: 1058: 1051: 1043: 1034: 1027: 1019: 1014:- Edemo (VM) 1011: 1003: 995: 987: 975: 967: 959: 954:- Soman (GD) 951: 946:- Sarin (GB) 943: 938:- Tabun (GA) 935: 927: 910: 872: 868: 850: 844: 834: 827: 822: 817: 807:October 2013 804: 800:adding to it 795: 772: 768: 763: 758: 753: 740: 730: 724: 715: 714: 707: 693: 688: 679: 678: 661: 638: 629: 625: 598: 585: 576: 562: 549: 527: 507: 473: 456: 370: 337: 335: 322: 308: 300: 272: 267: 251: 243: 227: 207:World War II 204: 180:riot control 167:cannabinoids 137:Nerve agent 103: 96: 78:and to test 68:World War II 62:facility in 46: 4036:M1135 NBCRV 4000:Weteye bomb 3868:Mustard gas 3770:Operational 3751:Project 112 3157:findlaw.com 2980:www.cdc.gov 2806:(1): 1–13. 1976:, 4/6/2007 1400:derivative 1385:scopolamine 1371:of atropine 1327:CAS 51–34–3 1294:CAS 62–51–1 1279:- Malathion 1253:related to 1230:CAS 59-99-4 497:within the 211:nerve gases 147:scopolamine 25:Project 112 4219:Categories 4114:By country 3970:M55 rocket 3725:Operations 3631:(USAMRICD) 3472:October 1, 3446:October 1, 3420:October 1, 3394:October 1, 3368:October 1, 3137:October 1, 2986:2024-09-18 2883:2024-09-18 2845:(5): 521. 2740:2024-09-18 2734:HathiTrust 2277:2024-09-15 2235:2024-09-15 1956:2013-06-19 1785:2024-09-17 1694:October 1, 1666:2024-09-15 1562:(1994) on 1553:(1993) on 1513:Tom Pettit 1450:References 1398:belladonna 1387:derivative 1366:levorotary 1251:antagonist 1135:Dexetimide 902:incomplete 352:, such as 232:wrote the 141:including 128:pesticides 74:agents on 53:classified 51:conducted 3990:MC-1 bomb 3935:M2 mortar 3883:Munitions 2962:1740-634X 2923:0098-7484 2859:0003-990X 2820:0022-3565 2780:0033-3158 2675:1742-5255 2615:0006-2952 2576:0028-1298 2529:0022-3565 2490:0576-5544 2451:0003-9861 2355:0733-2467 2316:0007-1250 2185:0077-8923 2130:0003-9942 2048:1570-159X 2010:help page 1974:USA Today 1583:Citations 1578:magazine. 1497:segment. 1321:carbamate 1289:pesticide 1213:- Eserine 1200:- Tacrine 1052:EA 2148-A 670:Aftermath 283:mescaline 279:Camp King 176:Irritants 139:antidotes 126:carbamate 124:(OP) and 4203:Category 3995:M47 bomb 3852:Phosgene 3841:Chlorine 3786:Disposal 3734:Research 3552:Archived 3211:dtic.mil 3184:dtic.mil 2683:23176543 2537:17267583 2412:17109842 2373:33098213 2066:24179466 1989:Archived 1860:Hearings 1837:Archived 1812:Archived 1753:cite web 1406:See also 1346:- Ditran 1220:alkaloid 1211:CS 58525 1198:CS 12602 1065:variant 1039:- CS gas 779:Lawsuits 646:and the 621:euphoria 553:dementia 535:and the 481:and the 309:General 190:caffeine 143:atropine 88:vaccines 64:Maryland 4067:MKULTRA 4021:M93 Fox 3163:May 20, 3066:citing 3012:(1982). 2364:7821204 2193:5257403 2165:Bibcode 2057:3648782 1628:(1982). 1564:A&E 1318:choline 1158:EA 5823 1150:EA 5365 1142:EA 4942 1131:EA-4929 1124:EA 3834 1116:EA 3580 1108:EA 3528 1100:EA 3443 1092:EA 3167 1084:EA 3148 1075:EA 2277 1059:EA 2233 1044:EA 2092 1036:EA 1779 1028:EA 1729 1020:EA 1701 1012:EA 1664 1004:EA 1653 996:EA 1517 988:EA 1508 976:EA 1298 968:EA 1285 960:EA 1212 952:EA 1210 944:EA 1208 936:EA 1205 928:EA 1152 609:agonist 238:enzymes 196:History 186:Alcohol 132:Mustard 58:at the 4185:(1933) 4177:(1942) 4140:Events 4131:Israel 4126:Canada 3827:Agents 3076:  3058:  3024:(1985) 3018:(1984) 2960:  2921:  2857:  2818:  2778:  2681:  2673:  2613:  2574:  2535:  2527:  2488:  2449:  2410:  2371:  2361:  2353:  2314:  2268:  2226:  2191:  2183:  2138:666613 2136:  2128:  2087:  2064:  2054:  2046:  1925:  1897:  1640:(1985) 1634:(1984) 1534:Dachau 1369:isomer 1255:Curare 839:, and 422:12.5% 414:13.2% 406:14.2% 398:14.5% 390:29.9% 364:, and 221:, and 182:agents 169:, and 134:agents 86:, and 4166:Media 3862:Sarin 2562:(1). 1729:(PDF) 1162:as a 859:Code. 819:them. 603:is a 446:7.2% 438:2.1% 430:6.4% 223:sarin 219:soman 215:tabun 118:sarin 4026:MOPP 4016:CAIS 3870:(HD) 3864:(GB) 3848:(DF) 3837:(BZ) 3474:2013 3448:2013 3422:2013 3396:2013 3370:2013 3219:2017 3192:2017 3165:2016 3139:2013 3074:ISBN 3056:ISBN 2958:ISSN 2919:ISSN 2903:JAMA 2855:ISSN 2816:ISSN 2776:ISSN 2679:PMID 2671:ISSN 2611:ISSN 2572:ISSN 2533:PMID 2525:ISSN 2486:ISSN 2447:ISSN 2408:PMID 2369:PMID 2351:ISSN 2312:ISSN 2266:ISBN 2224:ISBN 2189:PMID 2181:ISSN 2134:PMID 2126:ISSN 2085:ISBN 2062:PMID 2044:ISSN 1923:ISBN 1895:ISBN 1759:link 1745:2024 1696:2013 1489:The 1331:an 1313:, a 1285:and 1174:) + 1153:- GV 1077:- BZ 1061:- A 1022:- VX 998:- VE 990:- VG 982:MDMA 708:The 683:The 462:and 336:The 188:and 178:and 145:and 104:The 2950:doi 2911:doi 2907:200 2878:CNN 2847:doi 2808:doi 2804:320 2768:doi 2764:180 2663:doi 2603:doi 2564:doi 2560:231 2517:doi 2513:321 2478:doi 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Index

Project MKUltra
Project 112
U.S. Army Chemical Corps
classified
human subject research
Edgewood Arsenal
Maryland
World War II
chemical warfare
military personnel
protective clothing
pharmaceuticals
vaccines
psychochemical warfare
Department of Defense
chemical agents
VX
sarin
organophosphorus
carbamate
Mustard
antidotes
atropine
scopolamine
2-PAM chloride
LSD
PCP
cannabinoids
BZ
Irritants

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