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Folding (chemistry)

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in a protein. The shape of the folded protein can be used to understand its function and design drugs to influence the processes that it is involved in.
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There is also a great deal of interest in the construction of artificial folding molecules or
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A Field Guide to Foldamers. Hill, D. J.; Mio, M. J.; Prince, R. B.; Hughes, T.; Moore, J. S.
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The most active area of interest in the folding of molecules is the process of
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and coworkers in Helv. Chim. Acta., 2003, 86, 1598–1624.
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is the process by which a molecule assumes its shape or
208: 191: 82:, which analyses the specific sequences of 198: 184: 47:. The process can also be described as 18: 16:How a molecule assumes its conformation 209: 150: 13: 14: 243: 154: 1: 118: 75:, and electrostatic effects. 170:. You can help Knowledge by 49:intramolecular self-assembly 7: 96: 10: 248: 149: 217:Supramolecular chemistry 57:noncovalent interactions 53:molecular self-assembly 23:Crystal structure of a 63:, metal coordination, 32: 232:Stereochemistry stubs 22: 69:van der Waals forces 103:Secondary structure 108:Tertiary structure 73:pi-pi interactions 65:hydrophobic forces 33: 222:Self-organization 179: 178: 141:10.1021/cr990120t 239: 200: 193: 186: 158: 151: 113:Circuit topology 61:hydrogen bonding 247: 246: 242: 241: 240: 238: 237: 236: 227:Stereochemistry 207: 206: 205: 204: 164:stereochemistry 147: 121: 99: 80:protein folding 17: 12: 11: 5: 245: 235: 234: 229: 224: 219: 203: 202: 195: 188: 180: 177: 176: 159: 145: 144: 120: 117: 116: 115: 110: 105: 98: 95: 15: 9: 6: 4: 3: 2: 244: 233: 230: 228: 225: 223: 220: 218: 215: 214: 212: 201: 196: 194: 189: 187: 182: 181: 175: 173: 169: 166:article is a 165: 160: 157: 153: 152: 148: 142: 138: 134: 130: 127: 123: 122: 114: 111: 109: 106: 104: 101: 100: 94: 92: 87: 85: 81: 76: 74: 70: 66: 62: 58: 54: 50: 46: 42: 38: 30: 26: 21: 172:expanding it 161: 146: 135:, 3893-4011 132: 128: 125: 88: 77: 51:, a type of 48: 45:conformation 40: 34: 27:reported by 84:amino acids 211:Categories 126:Chem. Rev. 119:References 59:, such as 91:foldamers 37:chemistry 97:See also 25:foldamer 41:folding 162:This 168:stub 129:2001 29:Lehn 137:doi 133:101 35:In 213:: 131:, 71:, 67:, 39:, 199:e 192:t 185:v 174:. 143:. 139::

Index


foldamer
Lehn
chemistry
conformation
molecular self-assembly
noncovalent interactions
hydrogen bonding
hydrophobic forces
van der Waals forces
pi-pi interactions
protein folding
amino acids
foldamers
Secondary structure
Tertiary structure
Circuit topology
doi
10.1021/cr990120t
Stub icon
stereochemistry
stub
expanding it
v
t
e
Categories
Supramolecular chemistry
Self-organization
Stereochemistry

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