43:
1734:
388:
34:
644:
Garcia-Vaquero, M.; Rajauria, G.; O'Doherty, J.V.; Sweeney, T. (2017-09-01). "Polysaccharides from macroalgae: Recent advances, innovative technologies and challenges in extraction and purification".
762:"The O-linked fucose glycosylation pathway: identification and characterization of a uridine diphosphoglucose: fucose-1,3-glucosyltransferase activity from Chinese hamster ovary cells"
879:
Dalziel, Martin; Crispin, Max; Scanlan, Christopher N.; Zitzmann, Nicole; Dwek, Raymond A. (2014-01-03). "Emerging
Principles for the Therapeutic Exploitation of Glycosylation".
528:
In the fucose-containing glycan structures, fucosylated glycans, fucose can exist as a terminal modification or serve as an attachment point for adding other sugars. In human
706:
752:
155:
401:
583:
have been designed to recruit the immune system to cancers cells have been manufactured in cell lines deficient in the enzyme for core fucosylation (
309:
865:
576:
998:
621:
580:
274:
408:
396:
514:
510:
931:
852:
Vanhooren, PT (1999). "L-fucose: occurrence, physiological role, chemical, enzymatic and microbial synthesis".
69:
251:
500:
Two structural features distinguish fucose from other six-carbon sugars present in mammals: the lack of a
991:
195:
541:
1058:
561:-Fucose has several potential applications in cosmetics, pharmaceuticals, and dietary supplements
533:
1551:
1737:
1545:
984:
1763:
1539:
803:"Exopolysaccharides enriched in rare sugars: bacterial sources, production, and applications"
757:
55:
1758:
1678:
260:
215:
131:
8:
572:
121:
1768:
962:
912:
829:
802:
687:
616:
370:
175:
954:
916:
904:
896:
834:
783:
733:
679:
671:
691:
1131:
966:
946:
888:
861:
824:
814:
773:
723:
661:
653:
490:
431:
332:
657:
540:. However, fucose at the non-reducing termini linked α-1,2 to galactose forms the
240:
1580:
1526:
1506:
1397:
447:
548:
1567:
1364:
1121:
1098:
1078:
532:-linked glycans, fucose is most commonly linked α-1,6 to the reducing terminal
472:
379:
950:
42:
1752:
1673:
1590:
1478:
1369:
900:
819:
778:
761:
675:
465:
892:
728:
711:
283:
InChI=1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3+,4+,5-,6?/m0/s1
1557:
1438:
1420:
1068:
1008:
958:
908:
838:
787:
737:
683:
564:
483:
293:
InChI=1/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3+,4+,5-,6?/m0/s1
866:
10.1002/(SICI)1097-4660(199906)74:6<479::AID-JCTB76>3.0.CO;2-E
643:
1715:
1703:
1575:
1486:
1234:
1229:
1169:
976:
932:"Improving Antibody-Based Cancer Therapeutics Through Glycan Engineering"
568:
505:
427:
1491:
1433:
1428:
1301:
1254:
611:
596:
547:
Fucose is released from fucose-containing polymers by an enzyme called
355:
206:
755:
666:
1649:
1645:
1600:
1514:
1496:
1463:
1448:
1269:
1192:
1154:
522:
378:
Except where otherwise noted, data are given for materials in their
1666:
1627:
1612:
1585:
1534:
1468:
1341:
1336:
1321:
1306:
1222:
1217:
1037:
1032:
552:
501:
475:
17:
154:
1708:
1688:
1656:
1631:
1621:
1617:
1595:
1458:
1453:
1443:
1353:
1316:
1311:
1289:
1274:
1264:
1181:
1159:
1143:
606:
504:
group on the carbon at the 6-position (C-6) (thereby making it a
494:
486:
469:
227:
1698:
1693:
1683:
1660:
1637:
1605:
1392:
1387:
1294:
1279:
1259:
1246:
1207:
1202:
1197:
1110:
1063:
1053:
1027:
1022:
479:
458:
454:
424:
186:
705:
1284:
1087:
878:
462:
166:
144:
751:
709:
567:
of antibodies has been established to reduce binding to the
584:
33:
930:
Yu, X; Marshall, MJE; Cragg, MS; Crispin, M (June 2017).
712:"Fucose: biosynthesis and biological function in mammals"
544:, the substructure of the A and B blood group antigens.
929:
1750:
239:
587:), thereby enhancing the in vivo cell killing.
130:
992:
710:Daniel J. Becker; John B. Lowe (July 2003).
1006:
999:
985:
468:Fucose is the fundamental sub-unit of the
214:
851:
828:
818:
777:
727:
665:
259:
577:antigen-dependent cellular cytotoxicity
1751:
980:
923:
286:Key: SHZGCJCMOBCMKK-DHVFOXMCSA-N
194:
174:
800:
296:Key: SHZGCJCMOBCMKK-DHVFOXMCBB
230:
13:
581:afucosylated monoclonal antibodies
14:
1780:
1733:
1732:
750:
704:
482:core of fucoidan is a suspected
386:
41:
32:
382:(at 25 °C , 100 kPa).
872:
845:
794:
744:
698:
637:
517:. It is equivalent to 6-deoxy-
1:
658:10.1016/j.foodres.2016.11.016
630:
854:J. Chem. Technol. Biotechnol
7:
646:Food Research International
590:
10:
1785:
360:164.16 g/mol
15:
1728:
1566:
1523:
1505:
1477:
1419:
1412:
1380:
1352:
1245:
1180:
1142:
1109:
1086:
1077:
1046:
1015:
951:10.1007/s40259-017-0223-8
575:cells and thereby reduce
376:
369:
364:
325:
305:
270:
114:
102:
68:
54:
49:
40:
31:
1059:Cyclohexane conformation
820:10.3389/fmicb.2015.00288
365:Supplementary data page
16:Not to be confused with
1552:Isomaltooligosaccharide
893:10.1126/science.1235681
1546:Galactooligosaccharide
779:10.1093/glycob/9.7.679
599:, the methyl ether of
96:-pyran-2,3,4,5-tetraol
1540:Fructooligosaccharide
758:Robert S. Haltiwanger
729:10.1093/glycob/cwg054
90:)-6-Methyltetrahydro-
70:Systematic IUPAC name
622:Verotoxin-producing
756:Daniel J. Moloney;
652:(Pt 3): 1011–1020.
28:
617:Fucosyltransferase
538:-acetylglucosamine
446:. It is found on
409:Infobox references
371:Fucose (data page)
23:
1746:
1745:
1724:
1723:
1408:
1407:
887:(6166): 1235681.
602:
560:
513:
417:Chemical compound
415:
414:
156:Interactive image
62:
1776:
1736:
1735:
1527:oligosaccharides
1507:Tetrasaccharides
1417:
1416:
1132:Dihydroxyacetone
1084:
1083:
1001:
994:
987:
978:
977:
971:
970:
936:
927:
921:
920:
876:
870:
869:
849:
843:
842:
832:
822:
801:Roca, C (2015).
798:
792:
791:
781:
754:
748:
742:
741:
731:
708:
702:
696:
695:
669:
641:
624:Escherichia coli
600:
558:
520:
509:
432:chemical formula
399:
393:
390:
389:
333:Chemical formula
263:
243:
232:
218:
198:
178:
158:
134:
108:
91:
63:-galactopyranose
60:
45:
36:
29:
26:
22:
1784:
1783:
1779:
1778:
1777:
1775:
1774:
1773:
1749:
1748:
1747:
1742:
1720:
1581:Oat beta-glucan
1568:Polysaccharides
1562:
1525:
1519:
1501:
1473:
1404:
1398:Neuraminic acid
1376:
1348:
1241:
1176:
1138:
1105:
1079:Monosaccharides
1073:
1042:
1011:
1005:
975:
974:
934:
928:
924:
877:
873:
850:
846:
807:Front Microbiol
799:
795:
749:
745:
703:
699:
642:
638:
633:
593:
518:
451:-linked glycans
445:
441:
437:
418:
411:
406:
405:
404: ?)
395:
391:
387:
383:
349:
345:
341:
335:
321:
318:
317:O1(O)(OC(O)1O)C
313:
312:
301:
298:
297:
294:
288:
287:
284:
278:
277:
266:
246:
233:
221:
201:
181:
161:
148:
137:
124:
110:
106:
98:
97:
64:
24:
21:
12:
11:
5:
1782:
1772:
1771:
1766:
1761:
1744:
1743:
1741:
1740:
1729:
1726:
1725:
1722:
1721:
1719:
1718:
1713:
1712:
1711:
1706:
1696:
1691:
1686:
1681:
1679:Levan beta 2→6
1676:
1671:
1670:
1669:
1653:
1642:
1641:
1640:
1624:
1615:
1610:
1609:
1608:
1603:
1598:
1593:
1588:
1583:
1572:
1570:
1564:
1563:
1561:
1560:
1555:
1549:
1543:
1537:
1531:
1529:
1521:
1520:
1518:
1517:
1511:
1509:
1503:
1502:
1500:
1499:
1494:
1489:
1483:
1481:
1479:Trisaccharides
1475:
1474:
1472:
1471:
1466:
1461:
1456:
1451:
1446:
1441:
1436:
1431:
1425:
1423:
1414:
1410:
1409:
1406:
1405:
1403:
1402:
1401:
1400:
1390:
1384:
1382:
1378:
1377:
1375:
1374:
1373:
1372:
1367:
1365:Mannoheptulose
1358:
1356:
1350:
1349:
1347:
1346:
1345:
1344:
1339:
1334:
1326:
1325:
1324:
1319:
1314:
1309:
1299:
1298:
1297:
1292:
1287:
1282:
1277:
1272:
1267:
1262:
1251:
1249:
1243:
1242:
1240:
1239:
1238:
1237:
1227:
1226:
1225:
1220:
1212:
1211:
1210:
1205:
1200:
1195:
1186:
1184:
1178:
1177:
1175:
1174:
1173:
1172:
1164:
1163:
1162:
1157:
1148:
1146:
1140:
1139:
1137:
1136:
1135:
1134:
1126:
1125:
1124:
1122:Glyceraldehyde
1115:
1113:
1107:
1106:
1104:
1103:
1102:
1101:
1099:Glycolaldehyde
1092:
1090:
1081:
1075:
1074:
1072:
1071:
1066:
1061:
1056:
1050:
1048:
1044:
1043:
1041:
1040:
1035:
1030:
1025:
1019:
1017:
1013:
1012:
1004:
1003:
996:
989:
981:
973:
972:
945:(3): 151–166.
922:
871:
860:(6): 479–497.
844:
793:
772:(7): 679–687.
743:
722:(7): 41R–53R.
697:
635:
634:
632:
629:
628:
627:
619:
614:
609:
604:
592:
589:
573:Natural Killer
515:-configuration
473:polysaccharide
443:
439:
435:
416:
413:
412:
407:
385:
384:
380:standard state
377:
374:
373:
367:
366:
362:
361:
358:
352:
351:
347:
343:
339:
336:
331:
328:
327:
323:
322:
320:
319:
316:
308:
307:
306:
303:
302:
300:
299:
295:
292:
291:
289:
285:
282:
281:
273:
272:
271:
268:
267:
265:
264:
256:
254:
248:
247:
245:
244:
236:
234:
226:
223:
222:
220:
219:
211:
209:
203:
202:
200:
199:
191:
189:
183:
182:
180:
179:
171:
169:
163:
162:
160:
159:
151:
149:
142:
139:
138:
136:
135:
127:
125:
120:
117:
116:
112:
111:
104:
100:
99:
73:
72:
66:
65:
58:
52:
51:
47:
46:
38:
37:
9:
6:
4:
3:
2:
1781:
1770:
1767:
1765:
1762:
1760:
1757:
1756:
1754:
1739:
1731:
1730:
1727:
1717:
1714:
1710:
1707:
1705:
1702:
1701:
1700:
1697:
1695:
1692:
1690:
1687:
1685:
1682:
1680:
1677:
1675:
1674:Hemicellulose
1672:
1668:
1665:
1664:
1663:
1662:
1658:
1654:
1652:
1651:
1647:
1643:
1639:
1636:
1635:
1634:
1633:
1629:
1625:
1623:
1619:
1616:
1614:
1611:
1607:
1604:
1602:
1599:
1597:
1594:
1592:
1589:
1587:
1584:
1582:
1579:
1578:
1577:
1574:
1573:
1571:
1569:
1565:
1559:
1556:
1553:
1550:
1547:
1544:
1541:
1538:
1536:
1533:
1532:
1530:
1528:
1522:
1516:
1513:
1512:
1510:
1508:
1504:
1498:
1495:
1493:
1490:
1488:
1485:
1484:
1482:
1480:
1476:
1470:
1467:
1465:
1462:
1460:
1457:
1455:
1452:
1450:
1447:
1445:
1442:
1440:
1437:
1435:
1432:
1430:
1427:
1426:
1424:
1422:
1421:Disaccharides
1418:
1415:
1411:
1399:
1396:
1395:
1394:
1391:
1389:
1386:
1385:
1383:
1379:
1371:
1370:Sedoheptulose
1368:
1366:
1363:
1362:
1361:Ketoheptoses
1360:
1359:
1357:
1355:
1351:
1343:
1340:
1338:
1335:
1333:
1330:
1329:
1328:Deoxy sugars
1327:
1323:
1320:
1318:
1315:
1313:
1310:
1308:
1305:
1304:
1303:
1300:
1296:
1293:
1291:
1288:
1286:
1283:
1281:
1278:
1276:
1273:
1271:
1268:
1266:
1263:
1261:
1258:
1257:
1256:
1253:
1252:
1250:
1248:
1244:
1236:
1233:
1232:
1231:
1228:
1224:
1221:
1219:
1216:
1215:
1214:Ketopentoses
1213:
1209:
1206:
1204:
1201:
1199:
1196:
1194:
1191:
1190:
1189:Aldopentoses
1188:
1187:
1185:
1183:
1179:
1171:
1168:
1167:
1165:
1161:
1158:
1156:
1153:
1152:
1151:Aldotetroses
1150:
1149:
1147:
1145:
1141:
1133:
1130:
1129:
1127:
1123:
1120:
1119:
1117:
1116:
1114:
1112:
1108:
1100:
1097:
1096:
1094:
1093:
1091:
1089:
1085:
1082:
1080:
1076:
1070:
1067:
1065:
1062:
1060:
1057:
1055:
1052:
1051:
1049:
1045:
1039:
1036:
1034:
1031:
1029:
1026:
1024:
1021:
1020:
1018:
1014:
1010:
1009:carbohydrates
1002:
997:
995:
990:
988:
983:
982:
979:
968:
964:
960:
956:
952:
948:
944:
940:
933:
926:
918:
914:
910:
906:
902:
898:
894:
890:
886:
882:
875:
867:
863:
859:
855:
848:
840:
836:
831:
826:
821:
816:
812:
808:
804:
797:
789:
785:
780:
775:
771:
767:
763:
760:(July 1999).
759:
753:
747:
739:
735:
730:
725:
721:
717:
713:
707:
701:
693:
689:
685:
681:
677:
673:
668:
663:
659:
655:
651:
647:
640:
636:
626:
625:
620:
618:
615:
613:
610:
608:
605:
598:
595:
594:
588:
586:
582:
579:. Therefore,
578:
574:
570:
566:
562:
556:
554:
550:
545:
543:
539:
537:
531:
526:
524:
516:
512:
507:
503:
498:
496:
492:
488:
485:
481:
480:α(1→3) linked
477:
474:
471:
467:
466:cell surface.
464:
460:
456:
452:
450:
433:
429:
426:
422:
410:
403:
398:
381:
375:
372:
368:
363:
359:
357:
354:
353:
337:
334:
330:
329:
324:
315:
314:
311:
304:
290:
280:
279:
276:
269:
262:
258:
257:
255:
253:
250:
249:
242:
238:
237:
235:
229:
225:
224:
217:
213:
212:
210:
208:
205:
204:
197:
193:
192:
190:
188:
185:
184:
177:
173:
172:
170:
168:
165:
164:
157:
153:
152:
150:
146:
141:
140:
133:
129:
128:
126:
123:
119:
118:
113:
101:
95:
89:
85:
81:
77:
71:
67:
57:
53:
48:
44:
39:
35:
30:
19:
1764:Deoxy sugars
1655:
1644:
1626:
1558:Maltodextrin
1439:Isomaltulose
1331:
1230:Deoxy sugars
1166:Ketotetrose
1069:Mutarotation
942:
938:
925:
884:
880:
874:
857:
853:
847:
810:
806:
796:
769:
766:Glycobiology
765:
746:
719:
716:Glycobiology
715:
700:
649:
645:
639:
623:
565:Fucosylation
563:
557:
549:α-fucosidase
546:
535:
529:
527:
499:
484:carbohydrate
448:
420:
419:
196:ChEMBL469449
115:Identifiers
103:Other names
93:
87:
83:
79:
75:
1759:Aldohexoses
1716:Xanthan gum
1704:Amylopectin
1576:Beta-glucan
1487:Maltotriose
1302:Ketohexoses
1255:Aldohexoses
1235:Deoxyribose
1170:Erythrulose
1128:Ketotriose
1118:Aldotriose
569:Fc receptor
506:deoxy sugar
428:deoxy sugar
326:Properties
1753:Categories
1492:Melezitose
1434:Isomaltose
1429:Cellobiose
1095:Aldodiose
667:10197/8191
631:References
612:Fucosidase
597:Digitalose
508:) and the
493:-mediated
356:Molar mass
261:28RYY2IV3F
207:ChemSpider
176:CHEBI:2181
143:3D model (
122:CAS Number
109:-galactose
56:IUPAC name
1769:Pyranoses
1646:Galactose
1601:Cellulose
1591:Sizofiran
1515:Stachyose
1497:Raffinose
1464:Trehalose
1449:Lactulose
1270:Galactose
1193:Arabinose
1155:Erythrose
1007:Types of
917:206548002
901:0036-8075
676:0963-9969
553:lysosomes
551:found in
542:H antigen
523:galactose
455:mammalian
430:with the
132:2438-80-4
1738:Category
1667:Glycogen
1650:Galactan
1628:Fructose
1613:Chitosan
1586:Lentinan
1535:Acarbose
1469:Turanose
1413:Multiple
1354:Heptoses
1342:Rhamnose
1337:Fuculose
1322:Tagatose
1307:Fructose
1223:Xylulose
1218:Ribulose
1182:Pentoses
1144:Tetroses
1047:Geometry
1038:Pyranose
1033:Furanose
959:28466278
939:BioDrugs
909:24385630
839:25914689
788:10362837
738:12651883
692:10531419
684:28865611
591:See also
502:hydroxyl
476:fucoidan
105:6-Deoxy-
59:6-Deoxy-
27:-Fucose
18:Fructose
1709:Amylose
1657:Glucose
1632:Fructan
1622:Dextran
1618:Dextrin
1596:Zymosan
1459:Sucrose
1454:Maltose
1444:Lactose
1393:Nonoses
1388:Octoses
1381:Above 7
1317:Sorbose
1312:Psicose
1290:Mannose
1275:Glucose
1265:Altrose
1247:Hexoses
1160:Threose
1111:Trioses
1016:General
967:3722081
881:Science
830:4392319
813:: 288.
607:Fucitol
603:-fucose
495:allergy
487:antigen
470:seaweed
453:on the
402:what is
400: (
350:
228:PubChem
1699:Starch
1694:Pectin
1689:Mannan
1684:Lignin
1661:Glucan
1638:Inulin
1606:Chitin
1332:Fucose
1295:Talose
1280:Gulose
1260:Allose
1208:Xylose
1203:Ribose
1198:Lyxose
1088:Dioses
1064:Epimer
1054:Anomer
1028:Ketose
1023:Aldose
965:
957:
915:
907:
899:
837:
827:
786:
736:
690:
682:
674:
478:. The
459:insect
425:hexose
421:Fucose
397:verify
394:
310:SMILES
187:ChEMBL
50:Names
1554:(IMO)
1548:(GOS)
1542:(FOS)
1524:Other
1285:Idose
963:S2CID
935:(PDF)
913:S2CID
688:S2CID
463:plant
423:is a
275:InChI
241:17106
216:16190
167:ChEBI
145:JSmol
955:PMID
905:PMID
897:ISSN
835:PMID
784:PMID
734:PMID
680:PMID
672:ISSN
585:FUT8
489:for
461:and
252:UNII
947:doi
889:doi
885:343
862:doi
825:PMC
815:doi
774:doi
724:doi
662:hdl
654:doi
571:of
491:IgE
231:CID
1755::
1659:/
1648:/
1630:/
1620:/
961:.
953:.
943:31
941:.
937:.
911:.
903:.
895:.
883:.
858:74
856:.
833:.
823:.
809:.
805:.
782:.
768:.
764:.
732:.
720:13
718:.
714:.
686:.
678:.
670:.
660:.
650:99
648:.
555:.
534:β-
525:.
497:.
457:,
440:12
344:12
86:,5
82:,4
78:,3
74:(2
1000:e
993:t
986:v
969:.
949::
919:.
891::
868:.
864::
841:.
817::
811:6
790:.
776::
770:9
740:.
726::
694:.
664::
656::
601:D
559:L
536:N
530:N
521:-
519:L
511:L
449:N
444:5
442:O
438:H
436:6
434:C
392:Y
348:5
346:O
342:H
340:6
338:C
147:)
107:L
94:H
92:2
88:S
84:R
80:R
76:S
61:L
25:L
20:.
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