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Jeff W. Lichtman

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Witvliet, Daniel; Mulcahy, Ben; Mitchell, James K.; Meirovitch, Yaron; Berger, Daniel R.; Wu, Yuelong; Liu, Yufang; Koh, Wan Xian; Parvathala, Rajeev; Holmyard, Douglas; Schalek, Richard L.; Shavit, Nir; Chisholm, Andrew D.; Lichtman, Jeff W.; Samuel, Aravinthan D. T.; Zhen, Mei (August 2021).
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Professor, a five-year appointment intended to recognize outstanding research and teaching. Lichtman is a faculty member within the Harvard Center for Brain Science and the Conte Center at Harvard University. From 2013 to 2016, he was a Grass Foundation Trustee.
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Feng, Guoping; Mellor, Rebecca H.; Bernstein, Michael; Keller-Peck, Cynthia; Nguyen, Quyen T.; Wallace, Mia; Nerbonne, Jeanne M.; Lichtman, Jeff W.; Sanes, Joshua R. (October 2000).
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and strengthening in response to experiences, and these experiences cause neurons which co-innervate the same cell to compete for dominance, thereby driving
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Additionally, the Lichtman lab developed a device called the Automatic Tape-Collecting Lathe Ultramicrotome (ATLUM), which can be used for automated
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Livet, Jean; Weissman, Tamily A.; Kang, Hyuno; Draft, Ryan W.; Lu, Ju; Bennis, Robyn A.; Sanes, Joshua R.; Lichtman, Jeff W. (November 2007).
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method, in which different fluorescent proteins are expressed stochastically in neighboring neurons within a mouse's
1066: 1071: 997: 725: 456: 386: 313: 449: 107: 971: 471: 337: 245: 1023: 280: 210: 810: 321: 57: 702: 606:"Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system" 374: 363: 1051: 368: 261: 125: 944: 897: 129: 1056: 762: 505:"Imaging Neuronal Subsets in Transgenic Mice Expressing Multiple Spectral Variants of GFP" 8: 832: 382: 366:. Subsequently, this technique has been adapted and used to map neural circuits in mice, 333: 880: 855: 672: 276: 214: 148: 521: 885: 659: 639: 625: 592: 559: 526: 491: 424: 272: 206: 875: 867: 733: 667: 651: 617: 584: 551: 516: 487: 483: 329: 171: 20: 428: 398: 390: 348: 249: 78: 504: 655: 359: 341: 237: 202: 42: 738: 605: 1045: 663: 629: 596: 563: 540:"Induction, assembly, maturation and maintenance of a postsynaptic apparatus" 530: 495: 436: 402: 305: 998:"Quest for the connectome: scientists investigate ways of mapping the brain" 889: 572: 539: 362:, thereby allowing neighboring neuronal processes to be distinguishable by 317: 292: 221: 218: 420: 297: 257: 176: 621: 406: 190: 640:"Connectomes across development reveal principles of brain maturation" 588: 555: 301: 871: 352: 296:
Up to ~160 colours were observed in the first Brainbow mice. (a) A
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Lichtman, Jeff W.; Conchello, José-Angel (December 2005).
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circuits of living animals. Lichtman hypothesizes that
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Sanes, Joshua R.; Lichtman, Jeff W. (November 2001).
427:, which are thought to be selectively vulnerable in 252:in 1973. In 1980, he received both MD and PhD from 470:Sanes, Joshua R.; Lichtman, Jeff W. (March 1999). 389:. Data from the Lichtman lab has been used in the 786:"First Santiago Ramón y Cajal Professor is named" 570: 300:innervating ear muscle. (b) An axon tract in the 1043: 275:Professor of Molecular and Cellular Biology at 209:Professor of Molecular and Cellular Biology and 1077:Washington University School of Medicine alumni 537: 469: 989: 902:: CS1 maint: multiple names: authors list ( 856:"A technicolour approach to the connectome" 723: 268:and conducted research there for 30 years. 777: 726:"Mapping the brain to understand the mind" 717: 916: 910: 879: 737: 671: 520: 1021: 995: 969: 783: 757: 755: 753: 751: 749: 463: 340:and automated imaging tools to identify 291: 266:Washington University School of Medicine 260:. After completing postdoctoral work at 963: 937: 854:Lichtman JW, Livet J, Sanes JR (2008). 847: 805: 803: 697: 695: 693: 691: 231: 1044: 825: 724:Brouillette, Monique (21 April 2022). 344:motifs throughout the nervous system. 279:. In 2013, he was named the inaugural 19:For the American criminal lawyer, see 1015: 746: 800: 688: 455:Transformative Research R01 Award, 442: 191:https://lichtmanlab.fas.harvard.edu/ 13: 730:Knowable Magazine | Annual Reviews 397:, developed in collaboration with 254:Washington University in St. Louis 213:Professor of Arts and Sciences at 144:Washington University in St. Louis 84:Washington University in St. Louis 14: 1093: 308:. From Lichtman and Sanes, 2008. 416:The lab is also interested in 705:. National Academy of Sciences 488:10.1146/annurev.neuro.22.1.389 248:. Lichtman received a BA from 1: 1022:Reuell P (28 November 2011). 681: 522:10.1016/s0896-6273(00)00084-2 476:Annual Review of Neuroscience 457:National Institutes of Health 387:neural circuit reconstruction 314:activity-dependent plasticity 450:National Academy of Sciences 264:, he established his lab at 108:National Academy of Sciences 7: 763:"Jeff W. Lichtman, MD, PhD" 544:Nature Reviews Neuroscience 287: 244:in 1951. He grew up in the 201:(born 1951) is an American 10: 1098: 1082:Harvard University faculty 784:Reuell P (11 March 2013). 656:10.1038/s41586-021-03778-8 271:In 2004, he was appointed 256:, where he was advised by 246:Northeastern United States 18: 917:Yandell K (13 May 2015). 739:10.1146/knowable-042122-1 573:"Fluorescence microscopy" 338:genetically modified mice 312:The Lichtman lab studies 186: 182: 170: 157: 136: 121: 114: 102: 92: 71: 63: 53: 35: 28: 1062:American neuroscientists 970:Gorman J (26 May 2014). 949:Center for Brain Science 811:"Jeff Lichtman, MD, PhD" 67:BA (1973), MD/PhD (1980) 58:United States of America 1067:21st-century scientists 996:Sample I (7 May 2012). 972:"All Circuits Are Busy" 375:Drosophila melanogaster 364:fluorescence microscopy 16:American neuroscientist 1072:Bowdoin College alumni 405:, to construct a full 369:Caenorhabditis elegans 347:In 2007, Lichtman and 309: 281:Santiago Ramón y Cajal 262:Harvard Medical School 211:Santiago Ramón y Cajal 464:Selected publications 295: 236:Lichtman was born in 1024:"Funding innovation" 951:. Harvard University 765:. Harvard University 351:first published the 232:Education and career 925:. Simons Foundation 622:10.1038/nature06293 383:electron microscopy 334:synaptic plasticity 224:technique known as 976:The New York Times 835:. Grass Foundation 833:"Jeff W. Lichtman" 703:"Jeff W. Lichtman" 310: 277:Harvard University 215:Harvard University 149:Harvard University 1026:. Harvard Gazette 788:. Harvard Gazette 650:(7871): 257–261. 443:Awards and honors 425:prefrontal cortex 273:Jeremy R. Knowles 207:Jeremy R. Knowles 196: 195: 116:Scientific career 1089: 1036: 1035: 1033: 1031: 1019: 1013: 1012: 1010: 1008: 993: 987: 986: 984: 982: 967: 961: 960: 958: 956: 941: 935: 934: 932: 930: 914: 908: 907: 901: 893: 883: 860:Nat Rev Neurosci 851: 845: 844: 842: 840: 829: 823: 822: 820: 818: 807: 798: 797: 795: 793: 781: 775: 774: 772: 770: 759: 744: 743: 741: 721: 715: 714: 712: 710: 699: 677: 675: 633: 600: 589:10.1038/nmeth817 567: 556:10.1038/35097557 534: 524: 499: 429:mental disorders 330:synaptic pruning 199:Jeff W. Lichtman 172:Doctoral advisor 166: 30:Jeff W. Lichtman 26: 25: 21:Jeffrey Lichtman 1097: 1096: 1092: 1091: 1090: 1088: 1087: 1086: 1042: 1041: 1040: 1039: 1029: 1027: 1020: 1016: 1006: 1004: 994: 990: 980: 978: 968: 964: 954: 952: 943: 942: 938: 928: 926: 915: 911: 895: 894: 872:10.1038/nrn2391 852: 848: 838: 836: 831: 830: 826: 816: 814: 809: 808: 801: 791: 789: 782: 778: 768: 766: 761: 760: 747: 722: 718: 708: 706: 701: 700: 689: 684: 616:(7166): 56–62. 583:(12): 910–919. 550:(11): 791–805. 466: 445: 399:Sebastian Seung 391:citizen science 349:Joshua R. Sanes 336:. The lab uses 290: 250:Bowdoin College 234: 164: 153: 88: 79:Bowdoin College 72:Alma mater 49: 40: 31: 24: 17: 12: 11: 5: 1095: 1085: 1084: 1079: 1074: 1069: 1064: 1059: 1054: 1038: 1037: 1014: 988: 962: 936: 909: 846: 824: 813:. Conte Center 799: 776: 745: 716: 686: 685: 683: 680: 679: 678: 634: 601: 577:Nature Methods 568: 535: 500: 482:(1): 389–442. 465: 462: 461: 460: 453: 444: 441: 360:nervous system 342:neural circuit 289: 286: 238:Salt Lake City 233: 230: 203:neuroscientist 194: 193: 188: 184: 183: 180: 179: 174: 168: 167: 161: 155: 154: 152: 151: 146: 140: 138: 134: 133: 123: 119: 118: 112: 111: 104: 100: 99: 94: 93:Known for 90: 89: 87: 86: 81: 75: 73: 69: 68: 65: 61: 60: 55: 51: 50: 43:Salt Lake City 41: 37: 33: 32: 29: 15: 9: 6: 4: 3: 2: 1094: 1083: 1080: 1078: 1075: 1073: 1070: 1068: 1065: 1063: 1060: 1058: 1055: 1053: 1052:Living people 1050: 1049: 1047: 1025: 1018: 1003: 999: 992: 977: 973: 966: 950: 946: 940: 924: 923:Spectrum News 920: 913: 905: 899: 891: 887: 882: 877: 873: 869: 866:(6): 417–22. 865: 861: 857: 850: 834: 828: 812: 806: 804: 787: 780: 764: 758: 756: 754: 752: 750: 740: 735: 731: 727: 720: 704: 698: 696: 694: 692: 687: 674: 669: 665: 661: 657: 653: 649: 645: 641: 635: 631: 627: 623: 619: 615: 611: 607: 602: 598: 594: 590: 586: 582: 578: 574: 569: 565: 561: 557: 553: 549: 545: 541: 536: 532: 528: 523: 518: 514: 510: 506: 501: 497: 493: 489: 485: 481: 477: 473: 468: 467: 458: 454: 451: 447: 446: 440: 438: 437:schizophrenia 434: 430: 426: 422: 419: 414: 412: 409:of the mouse 408: 404: 403:Winfried Denk 400: 396: 392: 388: 384: 379: 377: 376: 371: 370: 365: 361: 357: 354: 350: 345: 343: 339: 335: 331: 327: 323: 319: 315: 307: 306:dentate gyrus 303: 299: 294: 285: 282: 278: 274: 269: 267: 263: 259: 255: 251: 247: 243: 239: 229: 227: 223: 220: 216: 212: 208: 204: 200: 192: 189: 185: 181: 178: 175: 173: 169: 162: 160: 156: 150: 147: 145: 142: 141: 139: 135: 131: 127: 124: 120: 117: 113: 109: 105: 101: 98: 95: 91: 85: 82: 80: 77: 76: 74: 70: 66: 62: 59: 56: 52: 48: 44: 38: 34: 27: 22: 1028:. Retrieved 1017: 1005:. Retrieved 1002:The Guardian 1001: 991: 979:. Retrieved 975: 965: 953:. Retrieved 948: 939: 927:. Retrieved 922: 912: 898:cite journal 863: 859: 849: 837:. Retrieved 827: 815:. Retrieved 790:. Retrieved 779: 767:. Retrieved 729: 719: 707:. Retrieved 647: 643: 613: 609: 580: 576: 547: 543: 515:(1): 41–51. 512: 508: 479: 475: 421:interneurons 415: 380: 373: 367: 355: 346: 311: 270: 235: 219:neuroimaging 205:. He is the 198: 197: 137:Institutions 132:neuroscience 115: 1057:1951 births 298:motor nerve 258:Dale Purves 222:connectomic 177:Dale Purves 54:Citizenship 1046:Categories 682:References 418:inhibitory 407:connectome 664:1476-4687 630:1476-4687 597:1548-7105 564:1471-0048 531:0896-6273 496:0147-006X 322:autonomic 304:. c) The 302:brainstem 126:Molecular 64:Education 890:18446160 448:Member, 431:such as 353:Brainbow 328:undergo 288:Research 226:Brainbow 130:cellular 106:Member, 97:Brainbow 945:"ATLUM" 881:2577038 673:8756380 423:in the 395:EyeWire 187:Website 888:  878:  670:  662:  644:Nature 628:  610:Nature 595:  562:  529:  509:Neuron 494:  459:(2011) 452:(2014) 433:autism 411:retina 372:, and 165:(1980) 163:  159:Thesis 128:& 122:Fields 110:(2014) 103:Awards 1030:9 May 1007:9 May 981:9 May 955:9 May 929:9 May 839:9 May 817:9 May 792:9 May 769:9 May 709:9 May 393:game 356:mouse 326:axons 318:motor 1032:2019 1009:2019 983:2019 957:2019 931:2019 904:link 886:PMID 841:2019 819:2019 794:2019 771:2019 711:2019 660:ISSN 626:ISSN 593:ISSN 560:ISSN 527:ISSN 492:ISSN 401:and 320:and 242:Utah 47:Utah 39:1951 36:Born 876:PMC 868:doi 734:doi 668:PMC 652:doi 648:596 618:doi 614:450 585:doi 552:doi 517:doi 484:doi 435:or 385:in 316:in 1048:: 1000:. 974:. 947:. 921:. 900:}} 896:{{ 884:. 874:. 862:. 858:. 802:^ 748:^ 732:. 728:. 690:^ 666:. 658:. 646:. 642:. 624:. 612:. 608:. 591:. 579:. 575:. 558:. 546:. 542:. 525:. 513:28 511:. 507:. 490:. 480:22 478:. 474:. 439:. 413:. 378:. 240:, 228:. 45:, 1034:. 1011:. 985:. 959:. 933:. 906:) 892:. 870:: 864:9 843:. 821:. 796:. 773:. 742:. 736:: 713:. 676:. 654:: 632:. 620:: 599:. 587:: 581:2 566:. 554:: 548:2 533:. 519:: 498:. 486:: 23:.

Index

Jeffrey Lichtman
Salt Lake City
Utah
United States of America
Bowdoin College
Washington University in St. Louis
Brainbow
National Academy of Sciences
Molecular
cellular
Washington University in St. Louis
Harvard University
Thesis
Doctoral advisor
Dale Purves
https://lichtmanlab.fas.harvard.edu/
neuroscientist
Jeremy R. Knowles
Santiago Ramón y Cajal
Harvard University
neuroimaging
connectomic
Brainbow
Salt Lake City
Utah
Northeastern United States
Bowdoin College
Washington University in St. Louis
Dale Purves
Harvard Medical School

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