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John K. Frost

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113:. Frost and other physicians expanded the field to allow for cytopathologic evaluation of the lung, bladder, and many other body sites. Frost was best known as a teacher of cytopathology. He organized and directed a school of 295:
Gill GW, Frost JK, and Miller KA, "A new formula for a half-oxidized hematoxylin solution that neither overstains nor requires differentiation", Acta Cytologica, vol. 18, no. 4, July–August 1974, pp, 300-311
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Cytology Award from the International Academy of Cytology. It is the highest award in the field. The citation described him as "the most prominent educator and teacher of cytopathology in the United States."
153:, where he remained for his entire career until his retirement in 1989. In 1959 he was the founding head of the division of cytopathology and continued to direct the division for 30 years. 105:- the microscopic study of individual body cells to detect cancer and other diseases. The first area of the body to be studied in this way was the female genital tract, using the 338: 174:
Frost died August 29, 1990, in Baltimore. The cause of death was from complications of therapy of lung cancer, although he was a lifelong nonsmoker.
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In addition to diagnostic services and professional training, his laboratory also carried out research, notably in the creation of the dyes (
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He was the author of 347 publications, including the definitive monograph on the subject of cytopathology,
265:"The cell in health and disease: an evaluation of cellular morphologic expression of biologic behavior" 171:
series, was created in Frost's cytopathology department in the 1970s by cytotechnologist Gary W. Gill.
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The division he founded and led at Hopkins is now named the John K. Frost Cytopathology Laboratory.
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In 1956 he took a position as an assistant professor of obstetrics and gynecology at
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and created and led a postgraduate Institute to teach the techniques to physicians.
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for his undergraduate degree. He received his medical degree from the
106: 164: 101:– 1990) was an American physician specializing in the field of 221:
Division of Cytopathology, Johns Hopkins Medical Institutions
209:"Dr. John K. Frost, 68, Researcher in Lung Cancer" 160:published in 1969 with a second edition in 1986. 69:one of the founders of the field of cytopathology 310: 120: 339:University of California, Berkeley alumni 135:University of California, San Francisco 311: 349:People from Sioux Falls, South Dakota 234:, Orlando Sentinel, September 1, 1990 204: 202: 13: 199: 131:University of California, Berkeley 14: 370: 334:Johns Hopkins Hospital physicians 211:, New York Times, August 31, 1990 329:Johns Hopkins University faculty 245:The Cell in Health and Disease, 158:The Cell in Health and Disease, 289: 277: 257: 237: 225: 214: 177: 1: 193: 95: 7: 10: 375: 344:Physicians from Baltimore 140: 127:Sioux Falls, South Dakota 81: 73: 65: 57: 49: 37: 32:Sioux Falls, South Dakota 25: 18: 284:Technical Data Sheet 192 185:In 1979 he received the 121:Early life and education 263:Frost, John Kingsbury, 147:Johns Hopkins Hospital 319:American pathologists 111:Georgios Papanikolaou 286:, Polysciences, Inc. 92:John Kingsbury Frost 151:Baltimore, Maryland 44:Baltimore, Maryland 129:. He attended the 125:Frost was born in 253:978-3-8055-0440-9 187:Maurice Goldblatt 89: 88: 366: 324:Cytopathologists 304: 293: 287: 281: 275: 267:, Karger, 1986, 261: 255: 243:Frost, John K., 241: 235: 229: 223: 218: 212: 206: 100: 97: 16: 15: 374: 373: 369: 368: 367: 365: 364: 363: 309: 308: 307: 294: 290: 282: 278: 273:978-3-805541503 262: 258: 242: 238: 232:"John K. Frost" 230: 226: 219: 215: 207: 200: 196: 180: 143: 123: 98: 45: 42: 41:August 29, 1990 33: 30: 21: 12: 11: 5: 372: 362: 361: 356: 351: 346: 341: 336: 331: 326: 321: 306: 305: 288: 276: 256: 247:Karger, 1969, 236: 224: 213: 197: 195: 192: 179: 176: 142: 139: 122: 119: 115:cytotechnology 87: 86: 83: 79: 78: 75: 71: 70: 67: 66:Known for 63: 62: 59: 55: 54: 51: 47: 46: 43: 39: 35: 34: 31: 27: 23: 22: 19: 9: 6: 4: 3: 2: 371: 360: 357: 355: 352: 350: 347: 345: 342: 340: 337: 335: 332: 330: 327: 325: 322: 320: 317: 316: 314: 303: 299: 292: 285: 280: 274: 270: 266: 260: 254: 250: 246: 240: 233: 228: 222: 217: 210: 205: 203: 198: 191: 188: 183: 175: 172: 170: 166: 161: 159: 154: 152: 148: 138: 136: 132: 128: 118: 116: 112: 108: 104: 103:cytopathology 93: 84: 80: 76: 72: 68: 64: 60: 56: 52: 48: 40: 36: 28: 24: 20:John K. Frost 17: 354:1920s births 291: 279: 259: 244: 239: 227: 216: 184: 181: 173: 162: 157: 155: 144: 124: 109:invented by 91: 90: 359:1990 deaths 178:Recognition 169:hematoxylin 99: 1922 77:Moira Keane 50:Nationality 313:Categories 194:References 58:Occupation 107:Pap smear 61:Physician 82:Children 53:American 302:4135333 29:c. 1922 300:  271:  251:  165:stains 141:Career 74:Spouse 298:PMID 269:ISBN 249:ISBN 38:Died 26:Born 149:in 315:: 201:^ 96:c. 94:( 85:7

Index

cytopathology
Pap smear
Georgios Papanikolaou
cytotechnology
Sioux Falls, South Dakota
University of California, Berkeley
University of California, San Francisco
Johns Hopkins Hospital
Baltimore, Maryland
stains
hematoxylin
Maurice Goldblatt


"Dr. John K. Frost, 68, Researcher in Lung Cancer"
Division of Cytopathology, Johns Hopkins Medical Institutions
"John K. Frost"
ISBN
978-3-8055-0440-9
"The cell in health and disease: an evaluation of cellular morphologic expression of biologic behavior"
ISBN
978-3-805541503
Technical Data Sheet 192
PMID
4135333
Categories
American pathologists
Cytopathologists
Johns Hopkins University faculty
Johns Hopkins Hospital physicians

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