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in
Parkinson's disease might be due to patients' anticipation of benefit, and that substantial dopamine is released in the brains of Parkinson's patients in response to placebo administration. Subsequent research by Stoessl has found that dopamine is released in the brain of Parkinson's patients when
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they are given a placebo, but only if they are told the probability of it being a real drug is 75 percent. He has said that "In
Parkinson's, as in many other conditions, there is an important placebo response and that can be measured with clinical outcomes."
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Stoessl, Alexander Jon; Bushnell, Mary
Catherine; Schulzer, Michael; Mak, Edwin; Troiano, Andre R.; Nandhagopal, R. (2010). "Response to Heat Pain Stimulation in Idiopathic Parkinson's Disease".
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376:; Ruth, TJ; de la Fuente-Fernández, R; Phillips, AG; Stoessl, AJ (August 2010). "Effects of expectation on placebo-induced dopamine release in Parkinson disease".
329:; Schulzer, M; Calne, DB; Stoessl, AJ (10 August 2001). "Expectation and dopamine release: mechanism of the placebo effect in Parkinson's disease".
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researcher. He is the director of the
Pacific Parkinson's Research Centre and Parkinson's Foundation Centre of Excellence at the
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in the UK for two years in the late 1980s. In 1996, he joined the faculty of UBC again, where he has remained ever since.
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27:(UBC). He is also the head of the division of neurology at this university. He is currently the President of the
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In 1984, Stoessl joined the faculty of the
University of British Columbia, where he worked on the
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and a residency in neurology at the
University of Western Ontario, where he studied alongside
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Holmes, D (November 2011). "Jon
Stoessl: besotted with the brain".
217:"Dr. A. Jon Stoessl recognized with 2006 Donald Calne Lectureship"
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Academic staff of the
University of British Columbia
50:in 1979, after which he completed an internship at
421:"Brain's reward system helps drive placebo effect"
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74:for two years. He then worked at the
514:University of Western Ontario alumni
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445:Bootle, Olly (17 February 2014).
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148:10.1111/j.1526-4637.2010.00866.x
504:Parkinson's disease researchers
419:Harding, Anne (4 August 2010).
519:Members of the Order of Canada
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378:Archives of General Psychiatry
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221:Parkinson Society Saskatchewan
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25:University of British Columbia
19:is a Canadian neurologist and
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264:10.1016/s1474-4422(11)70236-8
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115:Member of the Order of Canada
48:University of Western Ontario
76:Neuroscience Research Centre
68:positron emission tomography
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529:English emigrants to Canada
447:"The medicine in our minds"
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29:World Parkinson Coalition.
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477:publications indexed by
111:Parkinson Society Canada
34:Early life and education
343:10.1126/science.1060937
534:Canada Research Chairs
499:Canadian neurologists
252:The Lancet. Neurology
107:Canada Research Chair
92:which found that the
17:Alexander Jon Stoessl
38:Stoessl was born in
524:Placebo researchers
21:Parkinson's disease
101:Awards and honors
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258:(11): 955.
193:UBC website
488:Categories
121:References
172:205686167
156:1526-2375
117:in 2007.
456:23 April
451:BBC News
430:23 April
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398:20679593
374:Sossi, V
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327:Sossi, V
310:23 April
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458:2015
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