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387:), isotonic (0.9% sodium chloride) and hypotonic (0.65% sodium chloride). Isotonic solutions have the same salt concentration as the human body, whereas hypertonic solutions have a higher salt content and hypotonic solutions have a lower salt content. Isotonic saline nasal sprays are commonly used in infants and children to wash out the thick
438:. Decongestant nasal sprays are advised for short-term use only, preferably 5 to 7 days at maximum. Some doctors advise to use them 3 days at maximum. A recent clinical trial has shown that a corticosteroid nasal spray may be useful in reversing this condition. Topical nasal decongestants include:
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in many countries. They work to very quickly open up nasal passages by constricting blood vessels in the lining of the nose. Prolonged use of these types of sprays can damage the delicate mucous membranes in the nose. This causes increased inflammation, an effect known as
204:
is preferred for systemic therapy because it provides an agreeable alternative to injection or pills. Substances can be assimilated extremely quickly and directly through the nose. Many pharmaceutical drugs exist as nasal sprays for systemic administration (e.g.
734:
588:
Vaidyanathan S, Williamson P, Clearie K, Kahn F, Lipworth B (July 2010). "Fluticasone reverses oxymetazoline-induced tachyphylaxis of response and rebound congestion".
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291:, allergic rhinitis and non-allergic (perennial) rhinitis. They can reduce inflammation and histamine production in the nasal passages, and have been shown to relieve
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work by competing for receptor sites to block the function of histamine, thereby reducing the inflammatory effect. Antihistamine nasal sprays include:
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380:. They can also relieve nasal congestion and remove airborne irritants such as pollen and dust thereby providing sinus allergy relief.
233:. Nasal sprays are seen as a more efficient way of transporting drugs with potential use in crossing the blood–brain barrier.
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542:"Corticosteroids (inhaled and/or intranasal) in the treatment of respiratory allergy in children: safety vs. efficacy"
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Three types of nasal sprays preparations of sodium chloride are available including hypertonic (3% sodium chloride or
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are also available. There is however no trial-verified evidence that they have a measurable effect on symptoms.
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Combination use of two medications as nasal spray preparation has been frequently prescribed by doctors.
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Natural nasal sprays that include chemical complexes derived from plant sources such as
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512:"Breakthrough: Nasal Spray May Soon Replace Pills for Delivering Drugs to the Brain"
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is delivered to help moisturize dry or irritated nostrils. This is a form of
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Spraying into a nostril while closing the opposite nostril to assure the dose
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Spray that delivers medications locally in the nasal cavities or systemically
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395:. Hypertonic solutions may be more useful at drawing moisture from the
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if you can. Unsourced or poorly sourced material may be challenged and
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Journal of Respiratory and Critical Care Medicine
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nasal sprays can be used to relieve the symptoms of
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494:after Upjohn merged with Mylan to create Viatris.
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192:. They are used locally for conditions such as
368:sprays are typically non medicated. A mist of
49:Please review the contents of the article and
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490:In some countries, Dymista is marketed by
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466:List of some combination nasal sprays:
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315:. Corticosteroid nasal sprays include:
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628:Therapeutic Goods Administration (TGA)
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624:"Dymista/Dylastine (Viatris Pty Ltd)"
539:Rizzo MC, Solé D, Naspitz CK (2007).
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477:(brand names including Dymista)
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221:). Other applications include
51:add the appropriate references
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860:Effervescent powder or tablet
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1644:Patient-controlled analgesia
949:Orally disintegrating tablet
520:. Science Daily. 21 May 2014
209:-analgesics, treatments for
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425:nasal sprays are available
320:Beclomethasone dipropionate
303:. Side effects may include
223:hormone replacement therapy
36:reliable medical references
10:
1711:
1155:Relative analgesia machine
660:– via Business Wire.
652:. Pfizer. 16 November 2020
602:10.1164/rccm.200911-1701OC
200:. In some situations, the
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142:Actuation of a nasal
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709:at Wikimedia Commons
459:Allergy combinations
202:nasal delivery route
1527:Transdermal implant
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1264:Intrauterine device
1145:Anaesthetic machine
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231:Parkinson's disease
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678:. 16 November 2020
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65:"Nasal spray"
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61:Find sources:
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32:This article
30:
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1690:Nasal sprays
1675:Dosage forms
1629:Intraosseous
1619:Intracardiac
1558:Intravitreal
1520:Injector pen
1515:Subcutaneous
1486:
1456:Jet injector
1441:Dermal patch
1254:Vaginal ring
1222:Insufflation
1196:
974:Effervescent
748:dosage forms
707:Nasal sprays
680:. Retrieved
675:
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654:. Retrieved
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632:. Retrieved
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596:(1): 19–24.
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522:. Retrieved
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423:Decongestant
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412:tea-tree oil
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215:osteoporosis
190:systemically
178:Nasal sprays
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144:spray bottle
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40:verification
33:
1614:Intravenous
1601:Circulatory
1586:Intrathecal
1510:Intradermal
1502:transdermal
1469:Parenterals
1375:Topical gel
1331:Murphy drip
1309:Suppository
1197:Nasal spray
1131:Oxygen mask
980:Chewing gum
919:Oral mucosa
372:containing
335:Flunisolide
330:Ciclesonide
313:nose bleeds
269:Olopatadine
159:nasal drops
155:Other names
131:Nasal spray
34:needs more
1669:Categories
1474:Injections
1237:Urogenital
1173:Ophthalmic
1029:inhalation
1003:Toothpaste
931:sublingual
895:Suspension
865:Herbal tea
498:References
471:Azelastine
350:Mometasone
325:Budesonide
297:runny nose
257:Azelastine
76:newspapers
1479:infusions
1411:Liposomes
1207:Eye drops
1202:Ear drops
1113:Vaporizer
1108:Nebulizer
998:Mouthwash
927:sublabial
850:Electuary
840:Decoction
408:capsaicin
385:sea water
305:headaches
289:hay fever
285:sinusitis
1650:PIC line
1591:Epidural
1431:Lip balm
1406:Hydrogel
1397:solution
1380:Liniment
1365:Ointment
1324:Hydrogel
1319:Solution
1304:Ointment
1244:Ointment
1217:Hydrogel
1212:Ointment
1008:Ointment
969:Lozenges
959:Lollipop
905:Tincture
890:Solution
870:Hydrogel
855:Emulsion
797:Pastille
672:"Brands"
610:20203244
575:13622570
567:17923074
524:30 March
301:sneezing
211:migraine
207:sedative
148:nostrils
1350:topical
1288:enteral
1249:Pessary
1079:Liquids
1052:Smoking
990:Liquids
885:Softgel
832:Liquids
792:Capsule
769:enteral
682:17 June
676:Viatris
656:17 June
492:Viatris
434:or the
184:in the
182:locally
90:scholar
55:removed
1545:Organs
1426:Lotion
1346:Dermal
1284:Rectal
1259:Douche
1039:Solids
976:tablet
941:Solids
923:buccal
880:Powder
845:Elixir
787:Tablet
779:Solids
634:8 July
608:
573:
565:
404:ginger
366:Saline
361:Saline
309:nausea
219:nausea
92:
85:
78:
71:
63:
1421:Cream
1385:Paste
1314:Enema
1266:(IUD)
1182:nasal
1104:(MDI)
1012:Spray
900:Syrup
571:S2CID
389:mucus
166:[
97:JSTOR
83:books
1695:Nose
1646:pump
1498:Skin
1395:DMSO
1390:Film
1178:otic
1133:and
954:Film
756:Oral
684:2024
658:2024
636:2024
606:PMID
563:PMID
526:2015
410:and
311:and
229:and
217:and
196:and
69:news
38:for
1123:Gas
598:doi
594:182
555:doi
188:or
1671::
1180:,
929:,
925:,
746:,
674:.
626:.
604:.
592:.
569:.
561:.
551:35
549:.
545:.
514:.
406:,
307:,
295:,
287:,
213:,
57:.
1603:,
1504:)
1500:(
1352:)
1348:(
1290:)
1286:(
1175:,
1071:0
1067:0
1031:)
1027:(
933:)
921:(
771:)
767:(
736:e
729:t
722:v
686:.
638:.
612:.
600::
577:.
557::
528:.
170:]
108:)
104:(
94:·
87:·
80:·
73:·
47:.
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