475:. it was used to test cells of ME/CFS patients, and in their first hypothesis, found it to be useful in distinguishing patients from healthy people. People with this disease are described as not using energy well and taking a long time to recover from energy expenditure; “the researchers decided to mimic this by stressing cells from 20 healthy controls and 20 ME/CFS patients by exposing them to increased levels of salt.” Rahim Esfandyarpour, lead author of the paper, said “When they face this new environment, their reaction is different than the reaction of healthy cells.”
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endurance decreased, Dafoe moved back home in May 2011. His mother cut her work as a clinical psychologist to five hours a week to spend full time on his daily care as he continued declining in function, while Davis continues his research career and helps with his son's daily care. Dafoe's need for treatment is the motivation for Davis to direct his medical and scientific research efforts toward this disease; he dropped all other projects in hand before his son became so ill.
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In April 2019, a notable result was reported; a test of blood without red cells (white cells in plasma), identified ME/CFS patients from healthy people with 100% accuracy in a small sample, 20 patients and 20 healthy people. The test used a biotechnological device designed by Davis and his team,
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Whitney Dafoe became ill with severe ME/CFS around 2009, declining from active and healthy in his career as a photographer to housebound, and by 2015 bed bound from this disease, unable to tolerate sounds and light, unable to do much at all, and eventually unable to eat, drink or speak. As his
313:'s department of biochemistry in 1972. He became an associate professor in 1980, full professor in 1980, and joined the department of genetics as a professor in 1990. He became director of the Stanford Genome Technology Center in 1994. He was elected a member of the
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survivors struggle with extreme exhaustion, memory lapses, and cognitive difficulties many months after they have been officially cleared as recovered. Davis is part of a high-level interagency work and research group with the
460:, a non-profit organization, whose goal is to fund and initiate research into chronic complex diseases. Presently the foundation is invested in The End ME/CFS Project, which aims to fast-track research for a cure for
471:“The small device that Davis and his colleagues created was originally developed to detect changes in electrical signals when cancer cells were exposed to different treatments.”, as described in
281:. Davis is a researcher in biotechnology and molecular genetics, particularly active in human and yeast genomics and the development of new technologies in genomics, with over 64 biotechnology
285:. In 2013, it was said of Davis that "A substantial number of the major genetic advances of the past 20 years can be traced back to Davis in some way." Since his son fell severely ill with
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in 2011, which noted among other achievements, two landmark papers, one in 1977 concerning genome editing and another in 1980 which "helped launch the field of genomics." In 2007,
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He has won recognition for his contributions to genetic research from many groups, as early as 1976 and as recently as 2015, from one of his alumni colleges and from the
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417:. In 2015, he received the Precision Medicine World Conference Luminary Award for his development of “R-loop Technique of Electron Microscopy”. In 2013, he received the
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to map the human genome in 1979; that proposal was turned down as being too ambitious. The
Stanford Genome Technology Center was included in the
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914:; Shalon, D.; Davis, R. W.; Brown, P. O. (1995). "Quantitative monitoring of gene expression patterns with a complementary DNA microarray".
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In 2013, Davis founded the
Stanford Chronic Fatigue Syndrome Research Center (now called ME/CFS Collaborative Research Center).
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Davis married Janet Dafoe in July 1969. Their son, Whitney Dafoe was born in 1983, followed by their daughter Ashley Davis.
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410:: "A substantial number of the major genetic advances of the past 20 years can be traced back to Davis in some way."
1180:"A nanoelectronics-blood-based diagnostic biomarker for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)"
762:"He pioneered technology that fueled the Human Genome Project. Now his greatest challenge is curing his own son"
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In 2013 Davis was named, alongside Elon Musk and Jeff Bezos, as one of today's nine greatest innovators by
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technique of electron microscopy for mapping coding RNAs which led to the discovery of RNA splicing. With
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survivors showed symptoms in line with those of ME/CFS. According to Fauci, "a considerable number" of
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Lashkari DA, DeRisi JL, McCusker JH, Namath AF, Gentile C, Hwang SY, Brown PO, Davis RW (1997).
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Esfandyarpour, R.; Kashi, A.; Nemat-Gorgani, M.; Wilhelmy, J.; Davis, R. W. (April 29, 2019).
1026:"Construction of a genetic linkage map in man using restriction fragment length polymorphisms"
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839:"Ronald W. Davis, PhD – Dickson Prize in Medicine – University of Pittsburgh"
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1154:"An experimental test may help confirm cases of chronic fatigue syndrome"
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University of
Pittsburgh University Marketing Communications Webteam.
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A Study of the Base
Sequence Arrangement in DNA by Electron Microscopy
699:"Who Will Tomorrow's Historians Consider Today's Greatest Inventors?"
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gave him its
Distinguished Alumni Award. In 2005, Davis received the
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Dr. Davis is the director of the
Scientific Advisory Board at the
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1264:"Finding an ME/CFS Biomarker, Ronald Davis, Stanford University"
436:. In 2004, he received the Lifetime Achievement Award from the
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fragments. Davis collaborated in the development of the first
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1120:"What does the nanoneedle research mean for ME/CFS patients?"
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Davis's research became more urgent and important after Dr.
440:. The National Academy of Sciences (NAS) gave him the 1982
277:, and director of the Stanford Genome Technology Center at
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Educational
Overview of Restriction Enzymes by Leslie Pray
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Members of the United States
National Academy of Sciences
1238:"Invisible Illness – Stories of Chronic Fatigue Syndrome"
1024:
Botstein, D.; White, R.; Skolnick, M.; Davis, R. (1980).
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Davis has focused his research efforts into the illness.
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Precision
Medicine World Conference Luminary Award (2015)
348:, and the gene expression profile of the first complete
617:"Happy 75th Birthday to Scientist Ronald W. Davis, PhD"
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723:"A geneticist's biggest challenge: Curing his own son"
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PMWC 2019 Silicon Valley
Luminary & Pioneer Awards
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1406:Myalgic encephalomyelitis/chronic fatigue syndrome
462:myalgic encephalomyelitis/chronic fatigue syndrome
287:myalgic encephalomyelitis/chronic fatigue syndrome
211:Myalgic encephalomyelitis/chronic fatigue syndrome
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669:"Center Publications – Genome Technology Center"
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328:, Davis was the first to demonstrate the use of
1184:Proceedings of the National Academy of Sciences
971:Proceedings of the National Academy of Sciences
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858:Proceedings of the National Academy of Sciences
1396:Stanford University School of Medicine faculty
446:Eli Lilly Award in Microbiology and Immunology
393:that began in 1990 and was completed in 2003.
385:He and his colleagues submitted a proposal to
178:Eli Lilly Award in Microbiology and Immunology
1326:Biographic Slideshow Video from 70th Birthday
1293:Ron Davis Lab Homepage at Stanford University
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791:National Academy of Sciences member directory
590:"2011 Gruber Genetics Prize: Ronald W. Davis"
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1303:History of Stanford Biochemistry Department
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1366:California Institute of Technology alumni
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507:looking at the long-term consequences of
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1298:Ron Davis Profile at Stanford University
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370:developed the method for constructing a
1152:Chadradhar, Shraddha (April 30, 2019).
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673:Stanford University School of Medicine
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269:(born July 17, 1941) is professor of
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852:Mertz, J. E.; Davis, R. W. (1972).
812:"Ronald W. Davis Honors and Awards"
643:"Genome Technology Center: History"
13:
1371:Eastern Illinois University alumni
1030:American Journal of Human Genetics
721:Haas, Michaela (January 2, 2021).
697:Allan, Nicole (October 23, 2013).
468:which is called the "nanoneedle".
430:California Institute of Technology
148:California Institute of Technology
67:California Institute of Technology
14:
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592:. Gruber Foundation at Yale. 2011
301:and a postdoctoral fellowship at
1391:People from Charleston, Illinois
1072:. Agoura Hills, California. 2019
1381:Human Genome Project scientists
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442:NAS Award in Molecular Biology
419:Warren Alpert Foundation Prize
309:, Davis joined the faculty of
172:NAS Award in Molecular Biology
135:Warren Alpert Foundation Prize
1:
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497:National Institutes of Health
229:Cold Spring Harbor Laboratory
936:10.1126/science.270.5235.467
760:Prior, Ryan (May 13, 2019).
415:National Academy of Sciences
378:that enabled and led to the
315:National Academy of Sciences
297:After completing his PhD at
159:Lifetime Achievement Award,
146:Distinguished Alumni Award,
7:
1270:(video). September 13, 2019
1066:"Scientific Advisory Board"
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444:. In 1976, he received the
438:Genetics Society of America
161:Genetics Society of America
71:Eastern Illinois University
10:
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1320:Gruber Prize Press Release
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434:Dickson Prize in Medicine
342:gene expression profiling
330:restriction endonucleases
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154:Dickson Prize in Medicine
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84:patents in biotechnology
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1376:History of biotechnology
1099:Open Medicine Foundation
1095:"The End ME/CFS Project"
1070:Open Medicine Foundation
992:10.1073/pnas.94.24.13057
621:Open Medicine Foundation
458:Open Medicine Foundation
452:Open Medicine Foundation
426:Gruber Prize in Genetics
355:Saccharomyces cerevisiae
141:Gruber Prize in Genetics
1205:10.1073/pnas.1901274116
1126:(video). April 29, 2019
1124:Open Medical Foundation
879:10.1073/pnas.69.11.3370
649:. Palo Alto, California
501:Veterans Administration
1244:(video). July 10, 2015
623:(video). July 12, 2016
562:"Past Luminary Awards"
400:Recognition and awards
505:Department of Defense
1361:American geneticists
1356:American biochemists
391:Human Genome Project
380:Human Genome Project
320:Davis developed the
81:Human Genome Project
57:Charleston, Illinois
1196:2019PNAS..11610250E
1190:(21): 10250–10257.
983:1997PNAS...9413057L
977:(24): 13057–13062.
928:1995Sci...270..467S
870:1972PNAS...69.3370M
675:. December 12, 2013
279:Stanford University
221:Stanford University
16:American biochemist
1308:2012-09-02 at the
303:Harvard University
225:Harvard University
203:Molecular Genetics
922:(5235): 467–470.
864:(11): 3370–3374.
787:"Ronald W. Davis"
647:Stanford Medicine
538:The Puzzle Solver
482:warned that some
293:Scientific career
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189:Scientific career
35:Ron Davis in 2021
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1272:. Retrieved
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332:for joining
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271:biochemistry
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259:Ronald Wayne
258:
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240:
217:Institutions
199:Biochemistry
188:
1346:1941 births
822:January 18,
796:January 18,
99:Janet Dafoe
1340:Categories
912:Schena, M.
727:Al Jazeera
545:References
513:Long COVID
503:, and the
464:(ME/CFS).
374:map using
350:eukaryotic
307:Jim Watson
47:1941-07-17
1158:Stat News
473:Stat News
368:Ray White
317:in 1983.
1306:Archived
1224:31036648
531:See also
509:COVID-19
488:COVID-19
484:COVID-19
352:genome (
311:Stanford
275:genetics
207:Genomics
117:Children
89:research
1331:YouTube
1215:6535016
1192:Bibcode
1052:6247908
1043:1686077
1011:9371799
979:Bibcode
952:6720459
944:7569999
924:Bibcode
916:Science
898:4343968
866:Bibcode
771:May 14,
732:June 8,
495:(CDC),
299:Caltech
283:patents
111:
103:
1248:May 3,
1222:
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1163:May 4,
1130:May 4,
1104:May 3,
1076:May 3,
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889:389773
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679:May 3,
653:May 3,
627:May 3,
596:May 5,
571:May 3,
519:Family
499:, the
366:, and
322:R-loop
247:(1970)
245:
236:Thesis
195:Fields
180:(1976)
174:(1981)
169:(1991)
163:(2004)
156:(2005)
150:(2007)
143:(2011)
137:(2013)
125:Awards
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