452:. Extract the pertinent information rather than just dumping low-level facts in a big list. For example, a long list of side effects is largely useless without some idea of which are common or serious. It can be illuminating to compare the drug with others in its class, or with older and newer drugs. Do not include dose or titration information except when they are extensively discussed by secondary sources, necessary for the discussion in the article, or when listing equivalent doses between different pharmaceuticals. Knowledge is also not an instruction manual or textbook and should not include instructions, advice (legal, medical or otherwise) or "how-to"s (see
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Include information on the chemical structure, stereochemistry, and chemical composition of the drug (e.g., free base, hydrochloride salt, etc.), physical characteristics, and notable chemical properties. Basic physicochemical properties such as melting pointing, solubility and other raw data should
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Where ambiguity exists as to the order in which drugs should be listed, the
British Approved Name for the combination (if one exists) or the order used by the manufacturer of the innovator brand should be used as a guide. For example, although no BAN exists for isosorbide dinitrate/hydralazine above,
925:
of the drug (for example which receptor subtype, ion channel population, isozyme, etc. the drug binds to) and if the drug blocks or activates that target. If relevant, mention what endogenous substance (neurotransmitter, hormone, substrate, etc.) is mimicked or blocked by the drug. Also describe
1045:
When writing about the history of the drug, only include this section if a sufficient amount of information on the drug's origin and/or first synthesis is available. If so, there should be a timeline of first synthesis, approval dates (U.S., Europe, UK, etc.), when marketing stopped or ownership
794:
This section details what forms the drug is available in. Information includes route of administration (e.g. oral, i.v., i.m., rectal, parenteral, intranasal. Oral forms of administration should be differentiated: tablets, crushable tablets, capsules (containing powder, gel, or sprinkle beads),
733:(USAN), development codenames, and the pronunciation -- that content can go in the infobox or the body of the article. In parentheses, list the main or initial brand names for the drug. If there are more than a few brand names, it is best to list these separately in the body of the article.
862:
List the adverse effects (including withdrawal symptoms, if applicable), as well as whether they are common, uncommon, or rare. The latter should only be mentioned if severe or otherwise notable. If possible, use specific statistics (be sure to cite sources!). Use side effect percentage with
721:. If a substance is used primarily as a drug, it should be noted so. Most of our readers access Knowledge on mobile devices, and excess naming becomes clutter that prevents swift access to the heart of the matter. Therefore, avoid cluttering the lead with multiple alternatives to the
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states that, "naming should give priority to what the majority of
English speakers would most easily recognize, with a reasonable minimum of ambiguity, while at the same time making linking to those articles easy and second nature." To that end, the World Health Organization
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The order of sections used in this guideline is recommended for readability and consistency between articles. The order suggested below is to emphasize information sought after by general readers. If you disagree with part of the style guide, please discuss changes on the
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to the chosen name. Non-standard proprietary combination preparations are discouraged, and fall outside the scope of this guideline. For example, a hypothetical "paracetamol/dextromethorphan/pseudoephedrine" page is discouraged and does not fall under this guideline.
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This section should go into further detail regarding what the medication is used for (for each major indication). Take special care with regulatory terms; since drug approvals vary from country to country, so does the distinction between approved and
521:, in which case the INN consists of two parts: the cation and the anion name. For example, "chlorphenamine maleate" is the INN modified (INNM) of a common first-generation antihistamine, thus the INN of the active moiety is used as the page title:
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without introducing errors or ambiguity. It is also reasonable to have the lead introduce content in the same order as the body of the text. In articles about drugs, they should describe the drug in question, as well as what it does. Note any
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Nonproprietary names are common nouns and hence should be lower case except in titles, the beginning of sentences, and in other situations that require capitalization. In contrast, trade names are proper nouns and should always be capitalized.
464:, intended to be read by the lay public so it is important to make technical material as accessible as possible to a wide audience but at the same time, not reducing the value of the article to more technical readers including
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Look for similar articles to check for what categories they belong to and add the article to any appropriate categories. If no similar articles can be found, add the article to any categories that seem appropriate. See
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is defined as "the section before the first headline. The table of contents, if displayed, appears between the lead section and the first headline." The lead of an article, if not the entire article, should be
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This section should describe the clinically relevant pharmacokinetic parameters of a drug or active metabolites and the mechanisms of clearance (e.g., specific enzyme systems or transporters). List the
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A page should mention other names in the lead section, in boldface, and the naming reference noted if possible. Those other common names of the drug should redirect to that page. For example, the page
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For articles on agents that are primarily recreational in use a section on the "Effects" of the agent early is recommended. This may be followed by sections on "Recreational uses" and "Medical uses".
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contains an updated list of of articles that don't follow this article title guideline and include the INN in the drugbox INN parameter; these articles are listed under the underscore section.
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is more appropriate. For example, "paracetamol" and "acetaminophen" are two common names for the same analgesic, and "paracetamol" is the INN. The relevant
Knowledge article has the page name
745:, but it should be included in every drug-related article. In the source code of the article, it appears before the article lead. It is displayed at the top-right corner of the page. For
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This is not a section — it comes after the last section in the article — but it is nonetheless an important part of any drug article. Most families of drugs already have a template; see
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pathways are impacted, what genes are up or down regulated, etc.) and how modulating the activity of the target ultimately translates into the desired therapeutic effect (that is, the
575:("/") character. For example, the standard combination of isosorbide dinitrate and hydralazine, used to treat congestive heart failure in African Americans, is described in the page
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There is currently no consensus whether codes for drug combinations should be added to articles about single drugs. If you do so, add "(combination with ])" or the like, using the
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enteric-coated or slow-release tables/capsules, syrup, sugar-free liquid, or powder (soluble or for suspension). Only include this section if the
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dosage information is not recommended as it may be construed as medical advice and be easily subject to vandalism or uninformed good-faith edits.
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This section should cover any known drug-microbiota interactions, particularly ones that occur in the gut for orally administered medications.
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501:(INN), also known as recommended International Nonproprietary Name (rINN), if one exists, except in unusual circumstances where another
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This section should note what other drugs/food interact with the drug in question, and what effect(s) are produced by this interaction.
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Under what circumstances should the drug in question not be used? Distinguish relative and absolute contraindications if possible.
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Full instructions are available on the page for each infobox. A suitable picture for the infobox is encouraged. For drugs, the 2D
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Primarily medication-related pages should contain information organized into the following sections, with attention to order.
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the manufacturer of the innovator brand "BiDil" lists the constituents in that order. Alternative names should be
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These are essential. Unreferenced "information" may be deleted or moved to the talk page. As guidelines we have
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placebo/control vs. percentage with drug/experimental. Always include adverse events highlighted with
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If applicable, describe recreational usage (i.e. abuse) and other illicit usage (for example, using
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525:. On the other hand, tiotropium is a quaternary ammonium cation, so the INN used as the title is
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should be strictly summarized, with clear linking to their main articles for further reading.
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Scientific Style and Format: the CBE Manual for
Authors, Editors and Publishers
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on how to format and present article content within their area of interest.
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Pharmacology/General/Main sections of drug page
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Global sales, distribution, cost in major
English speaking countries, etc.
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The article title and the first name to mention in the lead should be the
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INNs are published by the World Health
Organization in the journal
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for an immunosuppressant) for which template(s) to use.
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Knowledge:Reliable sources (medicine-related articles)
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field of the drugbox does not provide enough space.
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