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Thanks for the feedback and help. I see that per the verifiability policy, "If available, academic and peer-reviewed publications are usually the most reliable sources on topics such as history, medicine, and science." Given the size of the study, risk of bias, and the source (JAMA), it seems solid
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Torgersen, Jessie; Mezochow, Alyssa K.; Newcomb, Craig W.; Carbonari, Dena M.; Hennessy, Sean; Rentsch, Christopher T.; Park, Lesley S.; Tate, Janet P.; Bräu, Norbert; Bhattacharya, Debika; Lim, Joseph K.; Mezzacappa, Catherine; Njei, Basile; Roy, Jason A.; Taddei, Tamar H.; Justice, Amy C.; Lo Re,
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article. That article presents a scheme in the
Synthesis section, and the aim of consulting this source is to verify that the Scheme reflects the content of this source (per WP:VERIFY). Specifically, the scheme shows conversion of theophylline into a 7-(β-chloroethyl)-analog by treatment of the
1213:-compliant). Personally, I'd delete the bibliography section, which includes some not-yet-peer-reviewed preprints. I think the question for notability is what you noted: that the molecule is only in trials, not in actual use. Given that we have the heavily populated
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article. Any of the relevant quoted German text, pasted at Talk for that article, and any further comment you would wish to make, would be greatly appreciated, and would likely allow us to verify the information attributed to this source. Thank you.
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I've seen a lot of pharmacology navboxes (such as muscarinic receptor modulators, for an example), lots of them contain a lot of drugs that are not really known (a lot of them are redlinks), which is what I mean by "undocumented compounds"
749:
15 yrs experience across various fields of medicine, including product development, patient care, and basic science. I welcome you to reach out for support with existing articles or to contribute to new topics. See you around!
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I'm inclined not to make a hasty decision (either way). Part of this is because I generally prefer merging, but other people tell me that a short, focused article is better for mobile users (which is most of our page
902:
enough, but if reliable sources differ, that matters. I don't want to jump the gun, but I'm not convinced we need to wait. Also, the editorial IS a secondary source. LOL, you've made ~leetk (1337k) edits, Boghog.
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Much of the staggering mortality rates and health care costs associated with drug-induced liver injury (DILI) is clearly linked to 11 drugs not well-known for their hepatotoxic risk, per the editorial accompanying
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abstract, RĂĽcker et al first had to prepare the chemical sample they studied, hence this paper might contain a proscribed, quotable (copyable) synthetic method, and perhaps a scheme corresponding to the one at the
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I've seen a couple of editors "upgrade" their favorite subjects, perhaps in the mistaken belief that this will result in more editors working on the articles. I specifically suggest taking a look at what's in
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that I do not have the expertise to approve or decline right now. As it is within the scope of this project - is the language used appropriate for a substance that is currently used only in clinical trials?
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A (rather belated!) welcome over here. There don't seem to be many of us watching WikiProject
Pharmacology! Regardless, let's push on. It will be great to have you working on this project too!
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describes this cohort study as an "innovative methodologic approach". We need to wait for this study to be evaluated in reliable secondary sources before citing those secondary sources.
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In furtherance of editing an article, we would ask that any individual having access to a chemistry, pharmacology, or medical library that could give access to the following article,
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parent compound with a 1,2-dihaloethane, and then conversion of that analog, by treatment with the free base of amphetamine, to the fenethylline product (a
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So if anyone knew how to find lists (or something similar) with names of investigational drugs (names like "ADX-71441") that would be really great
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In my opinion, a dosage and a prescription are two different (albeit related, of course) things. I'd be inclined not to merge, for that reason. --
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I've read the draft page. It's well-written, and reliably sourced, with the caveat that the sources are mostly minor scientific journals (but
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Because so far I've been creating a lot of articles that were redlinks on the navboxes, but I'd love to add new compounds to said templates.
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I accepted it through AfC after commenting out the bibliography and altering some wording here and there. One possible concern is the use of
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Thnx much! Here if needed. I realized just today that I never joined the
Medicine project, so I just did that today. Cheers!
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I was just curious if anyone knew how to find names of these compounds (like specific keywords in a search engine)
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Vincent (24 June 2024). "Severe Acute Liver Injury After
Hepatotoxic Medication Initiation in Real-World Data".
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RĂĽcker G, Neugebauer M, Neugebauer M, Heiden PG (December 1987). "Zur chemischen
Stabilität des Fenetyllins" .
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to contribute here and at the
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988:) had 5-10 eptkpy. Eleven of these (64%) were not included in the highest hepatotoxicity category of
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on
Knowledge. If you would like to participate, please visit the project page, where you can join
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to high-importance. Please decide for yourselves how you'd like to have it assessed.
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Our presumption is that in performing the chemical stability studies reported in the
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Is there a good, well-sourced page that describes the technical difference between
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that they copy and paste the relevant synthetic text into a Talk entry at the
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composed of theophylline and amphetamine linked by a two carbon bridge).
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https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2820267
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as top-importance for this group, and after I removed the rating, has
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in particular, to see whether any spammers have been at work.
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Talk:Transgender hormone therapy#Requested move 15 July 2024
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Talk:Transgender hormone therapy#Requested move 15 July 2024
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Apparently we did not have such an article, but I created
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Hi, I'm not sure if this is the right place to ask this.
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that may be of interest to members of this WikiProject.
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1215:Category:Experimental cancer drugs
1045:Request for excerpt of text, from
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304:Knowledge:WikiProject Pharmacology
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1474:WikiProject Pharmacology articles
804:Integrate definitive new findings
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284:This page is within the scope of
1257:Finding "undocumented" compounds
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40:Click here to start a new topic.
852:10.1001/jamainternmed.2024.1836
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1405:19:48, 30 September 2024 (UTC)
1383:19:41, 30 September 2024 (UTC)
1369:18:58, 30 September 2024 (UTC)
1350:17:52, 30 September 2024 (UTC)
1323:04:41, 26 September 2024 (UTC)
1289:Importance ratings need review
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1:
1359:which hopefully is a start.
1284:22:29, 7 September 2024 (UTC)
982:sulfamethoxazole-trimethoprim
298:and see a list of open tasks.
37:Put new text under old text.
1140:. Opinions welcome. Thanks,
760:14:57, 17 January 2024 (UTC)
7:
1187:There is a promising draft
45:New to Knowledge? Welcome!
10:
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1413:I did some copyediting on
1373:Thanks for creating that.
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978:amoxicillin-clavulanate
782:09:10, 7 May 2024 (UTC)
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1072:10.1002/ardp.198700045
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844:JAMA Internal Medicine
725:Lowercase sigmabot III
498:Requested articles (1)
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70:avoid personal attacks
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1357:dosage (pharmacology)
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310:pharmacology articles
191:Auto-archiving period
1393:Medical prescription
1295:Legality of cannabis
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1060:Archiv der Pharmazie
1047:Archiv der Pharmazie
380:General information
346:a WikiProject Report
1415:Dose (biochemistry)
355:on 17 January 2009.
1161:Actioned. Thanks.
1136:See my comment at
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1395:. Thoughts?
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1131:Aclarubicin
970:fluconazole
930:thalidomide
535:Photographs
438:Departments
372:WikiProject
1458:Categories
1433:Tryptofish
1299:changed it
1234:Oncotarget
1219:Tryptofish
1032:RodRabelo7
871:This is a
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768:Gobucks821
752:Gobucks821
556:Historical
446:Assessment
974:captopril
946:isoniazid
922:erlotinib
918:stavudine
885:editorial
859:2168-6106
549:Workspace
542:Templates
83:if needed
66:Be polite
21:talk page
1387:Perhaps
1211:WP:MEDRS
1086:84235752
990:LiverTox
881:WP:MEDRS
655:: 1/2007
627:Archives
464:Research
352:Signpost
114:Archives
99:WT:PHARM
91:Shortcut
51:get help
1410:views).
1079:3439867
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1100:codrug
1049:(1987)
889:Boghog
817:, etc.
244:scale.
1240:Recon
1195:Recon
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236:This
119:Index
79:Seek
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1365:talk
1346:talk
1336:and
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1076:PMID
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998:talk
908:talk
893:talk
856:ISSN
823:talk
792:talk
778:talk
756:talk
694:2014
689:2013
684:2012
679:2011
674:2010
669:2009
664:2008
659:2007
580:talk
568:talk
482:talk
469:talk
456:talk
427:talk
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391:talk
68:and
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