279:
40:
269:
plays a key role in diverse aspects of cardiac differentiation and morphogenesis. (BMPs) are multifunctional signaling molecules critical for the development of AV node. BMP influences AV node development through Alk3 receptor (Activin receptor-like kinase 3). Abnormalities seen in BMP and Alk3 are
358:
The AV node's normal intrinsic firing rate without stimulation (such as that from the SA node) is 40–60 times/minute. This property is important because loss of the conduction system before the AV node should still result in pacing of the ventricles by the slower pacemaking ability of the AV node.
318:
through the atria along specialized conduction channels. This activates the AV node. The atrioventricular node delays impulses by approximately 0.09s. This delay in the cardiac pulse is extremely important: It ensures that the atria have ejected their blood into the ventricles first before the
372:) describes impairment of the electrical continuity between the atria and ventricles. It occurs when the atrial depolarization fails to reach the ventricles or is conducted with an abnormally long delay. It can result from an injury or be a genetically inherited disorder.
313:
of their cell membranes. Movement of ions across cell membranes causes these events. The cardiac conduction system (and AV node part of it) coordinates myocyte mechanical activity. A wave of excitation spreads out from the
598:
Saremi, F.; Abolhoda, A.; Ashikyan, O.; Milliken, J. C.; Narula, J.; Gurudevan, S. V.; Kaushal, K.; Raney, A. (2007). "Arterial Supply to
Sinuatrial and Atrioventricular Nodes: Imaging with Multidetector CT".
378:, which is caused by a dual AV node physiology and AVNRT can only occur in people with it, however almost half of the population have it, though only a few of them will develop AVNRT at some point in life.
347:, in which the more frequently the node is stimulated the slower it conducts. This is the property of the AV node that prevents rapid conduction to the ventricle in cases of rapid atrial rhythms, such as
222:, which conducts the normal electrical impulse from the atria to the ventricles. The AV node is quite compact (~1 x 3 x 5 mm). It is located at the center of
153:
962:
Sharma G, Linden MD, Schultz DS, Inamdar KV (January 2009). "Cystic tumor of the atrioventricular node: an unexpected finding in an explanted heart".
254:
individuals the blood supply is from the right coronary artery while in left dominant individuals it originates from the left circumflex artery.
636:"Abnormal Conduction and Morphology in the Atrioventricular Node of Mice With Atrioventricular Canal–Targeted Deletion of Alk3/Bmpr1a Receptor"
381:
1000:
129:
477:
226:—a triangle enclosed by the septal leaflet of the tricuspid valve, the coronary sinus, and the membranous part of the interatrial septum.
1018:
1430:
938:
283:
190:
68:
45:
492:
201:, and conducts the normal electrical impulse from the atria to the ventricles. The AV node is quite compact (~1 x 3 x 5 mm).
1045:
881:
805:
763:
459:
1106:
1101:
821:
Patterson E, Scherlag BJ (October 2002). "Decremental conduction in the posterior and anterior AV nodal inputs".
559:"Anatomical aspects of the arterial blood supply to the sinoatrial and atrioventricular nodes of the human heart"
375:
334:
235:
148:
80:
1508:
1285:
1038:
684:
262:
1309:
247:
1578:
1019:
https://web.archive.org/web/20070929080346/http://www.healthyheart.nhs.uk/heart_works/heart03.shtml
112:
1289:
1202:
1170:
1158:
17:
797:
783:
755:
741:
451:
437:
1527:
1305:
1277:
1269:
1031:
873:
406:
369:
278:
270:
associated with some cardiovascular diseases like
Ebstein's anomaly and AV conduction disease.
243:
160:
136:
124:
1003:
at Human
Anatomy Online, SUNY Downstate Medical Center – "The conduction system of the heart."
1355:
1323:
1197:
1116:
1011:
239:
865:
1552:
1445:
1381:
1301:
1273:
1220:
1121:
903:
The
Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology
8:
1503:
1086:
489:
348:
189:'s atria and ventricles to coordinate beating in the top of the heart; it is part of the
1547:
1515:
1175:
1148:
1096:
846:
660:
635:
393:
223:
215:
194:
704:
651:
534:
509:
1557:
1485:
1435:
1281:
1180:
1165:
1153:
1081:
1076:
979:
920:
877:
866:
838:
801:
793:
759:
751:
709:
665:
616:
580:
539:
455:
447:
413:
291:
850:
1319:
1215:
1185:
971:
910:
830:
699:
655:
647:
608:
570:
529:
521:
339:
the second "pathway" has a faster conduction velocity but longer refractory period.
975:
329:
AV conduction during normal cardiac rhythm occurs through two different pathways:
1465:
1460:
1440:
1313:
1297:
1293:
1091:
781:
739:
496:
435:
389:
315:
117:
685:"ACC/AHA/ESC guidelines for the management of patients with atrial fibrillation"
322:
This also protects the ventricles from excessively fast rate response to atrial
238:. The origin of this artery is most commonly (80–90% of hearts) a branch of the
1422:
1363:
1345:
1259:
1143:
575:
558:
490:
Harrison's
Principles of Internal Medicine, 17e" Section 3: Disorders of Rhythm
352:
310:
306:
302:
266:
219:
198:
834:
612:
1572:
1455:
1006:
939:"Dual Atrioventricular Nodal Physiology - an overview | ScienceDirect Topics"
141:
290:
The AV node receives two inputs from the right atrium: posteriorly, via the
1371:
1367:
1359:
1265:
983:
924:
842:
713:
669:
620:
584:
525:
63:
543:
473:
471:
1495:
1477:
1412:
1404:
1351:
1255:
1245:
1192:
782:
Gray, Huon H.; Keith D. Dawkins; Iain A. Simpson; John M. Morgan (2002).
740:
Gray, Huon H.; Keith D. Dawkins; Iain A. Simpson; John M. Morgan (2002).
436:
Gray, Huon H.; Keith D. Dawkins; Iain A. Simpson; John M. Morgan (2002).
323:
1520:
1335:
1023:
915:
898:
468:
385:
39:
166:
510:"Arterial blood supply of the atrioventricular node and main bundle"
507:
1009:
at The
Anatomy Lesson by Wesley Norman (Georgetown University) (
789:
747:
556:
508:
Van der
Hauwaert LG, Stroobandt R, Verhaeghe L (October 1972).
443:
333:
the first "pathway" has a slow conduction velocity but shorter
295:
75:
597:
557:
Pejković, B.; Krajnc, I.; Anderhuber, F.; Kosutić, D. (2008).
1377:
1055:
634:
Stroud DM, Gaussin V, Burch JB, et al. (November 2007).
186:
92:
683:
Fuster V, Rydén LE, Asinger RW, et al. (October 2001).
899:"Genetics of atrioventricular conduction disease in humans"
961:
388:
origin and occurs exclusively in the area of the AV node,
872:(11 ed.). Philadelphia: Elsevier Saunders. p.
343:
An important property that is unique to the AV node is
27:
Part of the electrical conduction system of the heart
193:. The AV node lies at the lower back section of the
823:
863:
682:
633:
214:The AV node lies at the lower back section of the
820:
1570:
777:
775:
431:
429:
382:Cystic tumour of atrioventricular nodal region
1039:
692:Journal of the American College of Cardiology
563:The Journal of International Medical Research
772:
234:The blood supply of the AV node is from the
426:
376:Atrioventricular nodal re-entry tachycardia
1046:
1032:
730:. 6th ed. San Francisco: Benjamin Cummings
501:
242:, with the remainder originating from the
38:
914:
896:
703:
659:
574:
533:
191:electrical conduction system of the heart
69:Electrical conduction system of the heart
1053:
864:Guyton, Arthur C.; John E. Hall (2006).
362:
277:
250:of the coronary artery circulation. In
14:
1571:
1306:moderator band/septomarginal trabecula
726:Campbell, N., & Reece, J. (2002).
478:Full Size Picture triangle of-Koch.jpg
294:, and anteriorly, via the interatrial
1027:
368:Atrioventricular conduction disease (
24:
25:
1590:
994:
652:10.1161/CIRCULATIONAHA.107.696583
607:(1): 99–107, discussion 108–109.
955:
931:
890:
857:
814:
733:
229:
868:Textbook of Medical Physiology
720:
676:
627:
591:
550:
483:
257:
246:. This is associated with the
46:conduction system of the heart
13:
1:
976:10.1016/j.carpath.2008.10.011
705:10.1016/S0735-1097(01)01587-X
419:
286:showing atrioventricular node
236:atrioventricular nodal branch
81:Atrioventricular nodal branch
204:
7:
1509:sternopericardial ligaments
1286:valve of inferior vena cava
785:Lecture Notes on Cardiology
743:Lecture Notes on Cardiology
439:Lecture Notes on Cardiology
400:
273:
209:
10:
1595:
1107:posterior interventricular
897:Benson DW (October 2004).
576:10.1177/147323000803600410
404:
263:Bone morphogenetic protein
185:electrically connects the
48:. The AV node is labelled
1540:
1521:epicardium/visceral layer
1494:
1476:
1421:
1403:
1396:
1334:
1310:crista supraventricularis
1244:
1237:
1211:
1139:
1132:
1102:anterior interventricular
1069:
1062:
613:10.1148/radiol.2461070030
480:. Retrieved on 2008-12-22
159:
147:
135:
123:
111:
103:
91:
86:
74:
62:
57:
37:
32:
1001:Anatomy figure: 20:06-02
964:Cardiovascular Pathology
218:near the opening of the
197:near the opening of the
98:nodus atrioventricularis
1290:valve of coronary sinus
1203:atrioventricular septum
1171:interventricular septum
835:10.1023/A:1020833604423
284:heart conduction system
1528:fold of left vena cava
1278:limbus of fossa ovalis
1012:thoraxheartinternalner
526:10.1136/hrt.34.10.1045
407:anatomical terminology
345:decremental conduction
287:
244:left circumflex artery
161:Anatomical terminology
1324:pulmonary circulation
943:www.sciencedirect.com
514:British Heart Journal
495:July 7, 2011, at the
363:Clinical significance
319:ventricles contract.
281:
240:right coronary artery
179:atrioventricular node
33:Atrioventricular node
1553:Coronary circulation
1382:systemic circulation
1221:intervenous tubercle
384:(CTAVN) CTAVN is of
1504:fibrous pericardium
349:atrial fibrillation
1548:Circulatory system
1516:serous pericardium
1478:Pericardial cavity
1176:trabeculae carneae
1149:interatrial septum
916:10.1002/ar.a.20099
405:This article uses
394:interatrial septum
303:heart muscle cells
288:
216:interatrial septum
195:interatrial septum
44:Image showing the
1566:
1565:
1558:Coronary arteries
1536:
1535:
1486:pericardial sinus
1446:Bachmann's bundle
1436:cardiac pacemaker
1431:Conduction system
1392:
1391:
1282:crista terminalis
1233:
1232:
1229:
1228:
1181:chordae tendineae
1154:pectinate muscles
883:978-0-7216-0240-0
807:978-0-86542-864-5
794:Blackwell Science
765:978-0-86542-864-5
752:Blackwell Science
646:(22): 2535–2643.
520:(10): 1045–1051.
461:978-0-86542-864-5
448:Blackwell Science
414:Junctional rhythm
335:refractory period
292:crista terminalis
175:
174:
170:
16:(Redirected from
1586:
1401:
1400:
1356:atrial appendage
1320:pulmonary artery
1270:atrial appendage
1242:
1241:
1216:cardiac skeleton
1186:papillary muscle
1137:
1136:
1067:
1066:
1048:
1041:
1034:
1025:
1024:
988:
987:
959:
953:
952:
950:
949:
935:
929:
928:
918:
894:
888:
887:
871:
861:
855:
854:
818:
812:
811:
779:
770:
769:
737:
731:
724:
718:
717:
707:
698:(4): 1231–1266.
689:
680:
674:
673:
663:
631:
625:
624:
595:
589:
588:
578:
554:
548:
547:
537:
505:
499:
487:
481:
475:
466:
465:
433:
167:edit on Wikidata
164:
42:
30:
29:
21:
1594:
1593:
1589:
1588:
1587:
1585:
1584:
1583:
1579:Cardiac anatomy
1569:
1568:
1567:
1562:
1532:
1490:
1472:
1466:Purkinje fibers
1461:bundle branches
1417:
1388:
1346:pulmonary veins
1330:
1314:pulmonary valve
1298:right ventricle
1294:tricuspid valve
1225:
1207:
1159:terminal sulcus
1128:
1058:
1054:Anatomy of the
1052:
997:
992:
991:
960:
956:
947:
945:
937:
936:
932:
895:
891:
884:
862:
858:
819:
815:
808:
780:
773:
766:
738:
734:
725:
721:
687:
681:
677:
632:
628:
596:
592:
555:
551:
506:
502:
497:Wayback Machine
488:
484:
476:
469:
462:
434:
427:
422:
410:
403:
390:tricuspid valve
365:
316:sinoatrial node
301:Contraction of
276:
260:
232:
224:Koch's triangle
212:
207:
171:
53:
28:
23:
22:
15:
12:
11:
5:
1592:
1582:
1581:
1564:
1563:
1561:
1560:
1555:
1550:
1544:
1542:
1538:
1537:
1534:
1533:
1531:
1530:
1525:
1524:
1523:
1513:
1512:
1511:
1500:
1498:
1492:
1491:
1489:
1488:
1482:
1480:
1474:
1473:
1471:
1470:
1469:
1468:
1463:
1458:
1453:
1448:
1443:
1438:
1427:
1425:
1419:
1418:
1416:
1415:
1409:
1407:
1398:
1394:
1393:
1390:
1389:
1387:
1386:
1364:left ventricle
1340:
1338:
1332:
1331:
1329:
1328:
1260:coronary sinus
1250:
1248:
1239:
1235:
1234:
1231:
1230:
1227:
1226:
1224:
1223:
1218:
1212:
1209:
1208:
1206:
1205:
1200:
1195:
1190:
1189:
1188:
1183:
1178:
1173:
1163:
1162:
1161:
1156:
1151:
1140:
1134:
1130:
1129:
1127:
1126:
1125:
1124:
1119:
1111:
1110:
1109:
1104:
1099:
1094:
1084:
1079:
1073:
1071:
1064:
1060:
1059:
1051:
1050:
1043:
1036:
1028:
1022:
1021:
1016:
1004:
996:
995:External links
993:
990:
989:
970:(3): e75–e78.
954:
930:
909:(2): 934–939.
889:
882:
856:
829:(2): 137–148.
813:
806:
771:
764:
732:
719:
675:
626:
590:
569:(4): 691–698.
549:
500:
482:
467:
460:
424:
423:
421:
418:
417:
416:
402:
399:
398:
397:
379:
373:
364:
361:
353:atrial flutter
341:
340:
337:
311:repolarization
307:depolarization
275:
272:
267:cell signaling
259:
256:
252:right-dominant
231:
228:
220:coronary sinus
211:
208:
206:
203:
199:coronary sinus
173:
172:
163:
157:
156:
151:
145:
144:
139:
133:
132:
127:
121:
120:
115:
109:
108:
105:
101:
100:
95:
89:
88:
84:
83:
78:
72:
71:
66:
60:
59:
55:
54:
43:
35:
34:
26:
9:
6:
4:
3:
2:
1591:
1580:
1577:
1576:
1574:
1559:
1556:
1554:
1551:
1549:
1546:
1545:
1543:
1539:
1529:
1526:
1522:
1519:
1518:
1517:
1514:
1510:
1507:
1506:
1505:
1502:
1501:
1499:
1497:
1493:
1487:
1484:
1483:
1481:
1479:
1475:
1467:
1464:
1462:
1459:
1457:
1456:bundle of His
1454:
1452:
1449:
1447:
1444:
1442:
1439:
1437:
1434:
1433:
1432:
1429:
1428:
1426:
1424:
1420:
1414:
1411:
1410:
1408:
1406:
1402:
1399:
1395:
1385:
1383:
1379:
1373:
1369:
1365:
1361:
1357:
1353:
1349:
1347:
1342:
1341:
1339:
1337:
1333:
1327:
1325:
1321:
1315:
1311:
1307:
1303:
1299:
1295:
1291:
1287:
1283:
1279:
1275:
1271:
1267:
1263:
1261:
1257:
1252:
1251:
1249:
1247:
1243:
1240:
1236:
1222:
1219:
1217:
1214:
1213:
1210:
1204:
1201:
1199:
1196:
1194:
1191:
1187:
1184:
1182:
1179:
1177:
1174:
1172:
1169:
1168:
1167:
1164:
1160:
1157:
1155:
1152:
1150:
1147:
1146:
1145:
1142:
1141:
1138:
1135:
1131:
1123:
1120:
1118:
1115:
1114:
1112:
1108:
1105:
1103:
1100:
1098:
1095:
1093:
1090:
1089:
1088:
1085:
1083:
1080:
1078:
1075:
1074:
1072:
1068:
1065:
1061:
1057:
1049:
1044:
1042:
1037:
1035:
1030:
1029:
1026:
1020:
1017:
1014:
1013:
1008:
1007:thoraxlesson4
1005:
1002:
999:
998:
985:
981:
977:
973:
969:
965:
958:
944:
940:
934:
926:
922:
917:
912:
908:
904:
900:
893:
885:
879:
875:
870:
869:
860:
852:
848:
844:
840:
836:
832:
828:
824:
817:
809:
803:
799:
795:
791:
787:
786:
778:
776:
767:
761:
757:
753:
749:
745:
744:
736:
729:
723:
715:
711:
706:
701:
697:
693:
686:
679:
671:
667:
662:
657:
653:
649:
645:
641:
637:
630:
622:
618:
614:
610:
606:
602:
594:
586:
582:
577:
572:
568:
564:
560:
553:
545:
541:
536:
531:
527:
523:
519:
515:
511:
504:
498:
494:
491:
486:
479:
474:
472:
463:
457:
453:
449:
445:
441:
440:
432:
430:
425:
415:
412:
411:
408:
395:
391:
387:
383:
380:
377:
374:
371:
367:
366:
360:
356:
354:
350:
346:
338:
336:
332:
331:
330:
327:
326:(see below).
325:
320:
317:
312:
308:
304:
299:
297:
293:
285:
280:
271:
268:
264:
255:
253:
249:
245:
241:
237:
227:
225:
221:
217:
202:
200:
196:
192:
188:
184:
180:
168:
162:
158:
155:
152:
150:
146:
143:
140:
138:
134:
131:
128:
126:
122:
119:
116:
114:
110:
106:
102:
99:
96:
94:
90:
85:
82:
79:
77:
73:
70:
67:
65:
61:
56:
51:
47:
41:
36:
31:
19:
1541:Blood supply
1450:
1413:heart valves
1375:
1372:aortic sinus
1368:aortic valve
1360:mitral valve
1343:
1317:
1302:infundibulum
1274:fossa ovalis
1266:right atrium
1253:
1010:
967:
963:
957:
946:. Retrieved
942:
933:
906:
902:
892:
867:
859:
826:
822:
816:
784:
742:
735:
727:
722:
695:
691:
678:
643:
639:
629:
604:
600:
593:
566:
562:
552:
517:
513:
503:
485:
438:
357:
344:
342:
328:
321:
300:
289:
261:
251:
233:
230:Blood supply
213:
182:
178:
176:
130:A12.1.06.004
97:
49:
1496:Pericardium
1405:Endocardium
1352:left atrium
1256:venae cavae
1246:Right heart
1097:interatrial
640:Circulation
324:arrhythmias
258:Development
87:Identifiers
1423:Myocardium
1336:Left heart
1166:ventricles
948:2022-11-14
796:. p.
754:. p.
450:. p.
420:References
386:endodermal
104:Acronym(s)
601:Radiology
305:requires
282:Isolated
248:dominance
205:Structure
1573:Category
1238:Chambers
1133:Internal
1113:borders
1092:coronary
984:19144541
925:15372490
851:22728910
843:12397223
714:11583910
670:17998461
621:18024438
585:18652764
493:Archived
401:See also
370:AV block
274:Function
210:Location
1451:AV node
1441:SA node
1070:Surface
1063:General
728:Biology
661:2947829
544:5086972
183:AV node
118:D001283
107:AV node
58:Details
18:AV node
1397:Layers
1312:), →
1193:valves
982:
923:
880:
849:
841:
804:
790:Boston
762:
748:Boston
712:
668:
658:
619:
583:
542:
535:458545
532:
458:
444:Boston
392:, and
296:septum
265:(BMP)
76:Artery
64:System
1378:aorta
1358:) →
1198:cusps
1144:atria
1117:right
1087:sulci
1056:heart
847:S2CID
688:(PDF)
187:heart
165:[
93:Latin
1380:and
1374:) →
1322:and
1292:) →
1122:left
1082:apex
1077:base
980:PMID
921:PMID
878:ISBN
839:PMID
802:ISBN
760:ISBN
710:PMID
666:PMID
617:PMID
581:PMID
540:PMID
456:ISBN
309:and
177:The
154:9478
142:3954
125:TA98
113:MeSH
972:doi
911:doi
907:280
874:120
831:doi
798:157
756:136
700:doi
656:PMC
648:doi
644:116
609:doi
605:246
571:doi
530:PMC
522:doi
452:135
351:or
181:or
149:FMA
137:TA2
1575::
1366:→
1362:→
1350:→
1316:→
1308:,
1304:,
1296:→
1288:,
1284:,
1280:,
1276:,
1272:,
1264:→
1258:,
978:.
968:19
966:.
941:.
919:.
905:.
901:.
876:.
845:.
837:.
825:.
800:.
792::
788:.
774:^
758:.
750::
746:.
708:.
696:38
694:.
690:.
664:.
654:.
642:.
638:.
615:.
603:.
579:.
567:36
565:.
561:.
538:.
528:.
518:34
516:.
512:.
470:^
454:.
446::
442:.
428:^
355:.
298:.
1384:)
1376:(
1370:(
1354:(
1348:)
1344:(
1326:)
1318:(
1300:(
1268:(
1262:)
1254:(
1047:e
1040:t
1033:v
1015:)
986:.
974::
951:.
927:.
913::
886:.
853:.
833::
827:7
810:.
768:.
716:.
702::
672:.
650::
623:.
611::
587:.
573::
546:.
524::
464:.
409:.
396:.
169:]
52:.
50:2
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
