Knowledge

WikiPathways

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In addition to the pathway diagram, each pathway page also includes a description, bibliography, pathway version history and list of component genes and proteins with linkouts to public resources. For individual pathway nodes, users can access a list of other pathways with that node. Pathway changes
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Agrawal, Ayushi; Balcı, Hasan; Hanspers, Kristina; Coort, Susan L; Martens, Marvin; Slenter, Denise N; Ehrhart, Friederike; Digles, Daniela; Waagmeester, Andra; Wassink, Isabel; Abbassi-Daloii, Tooba; Lopes, Elisson N; Iyer, Aishwarya; Acosta, Javier Millán; Willighagen, Lars G; Nishida, Kozo;
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Slenter, Denise N.; Kutmon, Martina; Hanspers, Kristina; Riutta, Anders; Windsor, Jacob; Nunes, Nuno; MĂ©lius, Jonathan; Cirillo, Elisa; Coort, Susan L.; Digles, Daniela; Ehrhart, Friederike; Giesbertz, Pieter; Kalafati, Marianthi; Martens, Marvin; Miller, Ryan; Nishida, Kozo; Rieswijk, Linda;
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species. Using a search feature, one can locate a particular pathway by name, by the genes and proteins it contains, or by the text displayed in its description. The pathway collection can also be browsed with combinations of species names and ontology-based categories.
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can be monitored by displaying previous revisions or by viewing differences between specific revisions. Using the pathway history one can also revert to a previous revision of a pathway. Pathways can also be tagged with ontology terms from three major
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systems. WikiPathways was founded in 2008 by Thomas Kelder, Alex Pico, Martijn Van Iersel, Kristina Hanspers, Bruce Conklin and Chris Evelo. Current architects are Alex Pico and Martina Summer-Kutmon.
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Bohler, Anwesha; Wu, Guanming; Kutmon, Martina; Pradhana, Leontius Adhika; Coort, Susan L.; Hanspers, Kristina; Haw, Robin; Pico, Alexander R.; Evelo, Chris T. (20 May 2016).
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WikiPathways content is used to annotate and cross-link Knowledge articles covering various genes, proteins, metabolites and pathways. Here are a few examples:
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Martijn P van Iersel; Alexander R. Pico; Thomas Kelder; Jianjiong Gao; Isaac Ho; Kristina Hanspers; Bruce R Conklin; Chris T. Evelo (4 January 2010).
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Waagmeester, Andra; Kutmon, Martina; Riutta, Anders; Miller, Ryan; Willighagen, Egon L.; Evelo, Chris T.; Pico, Alexander R. (23 June 2016).
333: 309:, and RDF), WikiPathways supports a variety of ways to integrate and interact with pathway content. These include directed link-outs, 265:
The pathway content at WikiPathways is freely available for download in several data and image formats. WikiPathways is completely
906:"WikiPathways for plants: a community pathway curation portal and a case study in rice and arabidopsis seed development networks" 702:
Martijn P van Iersel; Thomas Kelder; Alexander R Pico; Kristina Hanspers; Susan Coort; Bruce R Conklin; Chris Evelo (2008).
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Riutta, Anders; Basaric, Helena; Evelo, Chris T; Willighagen, Egon L; Kutmon, Martina; Pico, Alexander R (6 November 2023).
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Kelder, T.; Pico, A. R.; Hanspers, K.; Van Iersel, M. P.; Evelo, C.; Conklin, B. R.; Hide, W. (2009). Hide, Winston (ed.).
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Each article at WikiPathways is dedicated to a particular pathway. Many types of molecular pathways are covered, including
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Alexander R Pico; Thomas Kelder; Martijn P van Iersel; Kristina Hanspers; Bruce R Conklin; Chris Evelo (22 July 2008).
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Waagmeester, Andra; Eijssen, Lars M.T.; Evelo, Chris T.; Pico, Alexander R.; Willighagen, Egon L. (10 November 2017).
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Hanumappa, Mamatha; Preece, Justin; Elser, Justin; Nemeth, Denise; Bono, Gina; Wu, Kenny; Jaiswal, Pankaj (2013).
338: 1210: 328: 206: 368: 1024:"Using the Semantic Web for Rapid Integration of WikiPathways with Other Biological Online Data Resources" 890: 773:"The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services" 1215: 259: 110: 1225: 1220: 274: 266: 701: 450: 226: 23: 1142:"COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms" 770: 593: 526: 230: 843:"WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research" 519: 1094: 1035: 976: 917: 97: 588: 422: 8: 270: 202: 39:
A wiki-based resource for collection, maintenance and distribution of biological pathways
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Martina Summer-Kutmon; Anders Riutta; Nuno Nunes; et al. (4 January 2016).
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is a community resource for contributing and maintaining content dedicated to
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Marvin Martens; Ammar Ammar; Anders Riutta; et al. (8 January 2021).
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Creative Commons Attribution-ShareAlike 3.0 Unported License
839: 384: 321:. This enables reuse in projects like COVID19 Disease Map. 306: 238: 178: 903: 431:, which is licensed in a way that permits reuse under the 653: 17:
WikiPathways: an open resource for biological pathways.
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software, a custom graphical pathway editing tool (
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All content is available under 891:"Browse pathways - WikiPathways" 351: 22: 1133: 1015: 956: 339:Category:WikiPathways templates 293:In addition to various primary 897: 883: 833: 647: 580: 513: 281:editor is available under the 1: 415: 1108:10.1371/journal.pone.0006447 1049:10.1371/journal.pcbi.1004989 990:10.1371/journal.pcbi.1004941 472:10.1371/JOURNAL.PBIO.0060184 7: 344: 283:Apache License, Version 2.0 88:http://www.wikipathways.org 10: 1242: 1028:PLOS Computational Biology 969:PLOS Computational Biology 1146:Molecular Systems Biology 209:, etc. and the supported 146: 134: 129: 116: 103: 93: 83: 67: 62: 48: 43: 35: 30: 21: 723:10.1186/1471-2105-9-399 1158:10.15252/msb.202110387 931:10.1186/1939-8433-6-14 847:Nucleic Acids Research 792:10.1186/1471-2105-11-5 661:Nucleic Acids Research 594:Nucleic Acids Research 527:Nucleic Acids Research 289:Access and integration 1211:Biological databases 607:10.1093/NAR/GKAA1024 435:, but not under the 428:"WikiPathWays:About" 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Index

WikiPathways logo
PMID
18651794
Data format
GPML
BioPAX
http://www.wikipathways.org
Pathways
Web service
REST
Sparql
http://sparql.wikipathways.org/sparql
License
Creative Commons 0
biological pathways
peer review
MediaWiki
PathVisio
gene
protein
metabolite
metabolic
signaling
regulatory
species
human
mouse
zebrafish
fruit fly
C. elegans

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