1268:
3119:
2112:
2357:
2646:
2140:), the larger the surface area, the lesser the pressure when an external force acts on it. Though the radii of the capillaries are very small, the network of capillaries has the largest surface area in the vascular network. They are known to have the largest surface area (485 mm^2) in the human vascular network. The larger the total cross-sectional area, the lower the mean velocity as well as the pressure.
3172:
233:. Deformation in red blood cells is induced by shear stress. When a suspension is sheared, the red blood cells deform and spin because of the velocity gradient, with the rate of deformation and spin depending on the shear rate and the concentration. This can influence the mechanics of the circulation and may complicate the measurement of blood
3094:
resistance to the blood flow. In the arteries, with the absence of diseases, there is very little or no resistance to blood. The vessel diameter is the most principal determinant to control resistance. Compared to other smaller vessels in the body, the artery has a much bigger diameter (4 mm), therefore the resistance is low.
3089:
measure pressure, is <120/80 mmHg. Other major arteries have similar levels of blood pressure recordings indicating very low disparities among major arteries. In the innominate artery, the average reading is 110/70 mmHg, the right subclavian artery averages 120/80 and the abdominal aorta
1590:
The
Reynolds number is directly proportional to the velocity and diameter of the tube. Note that NR is directly proportional to the mean velocity as well as the diameter. A Reynolds number of less than 2300 is laminar fluid flow, which is characterized by constant flow motion, whereas a value of over
1334:
In a normal circulatory system, the volume of blood returning to the heart each minute is approximately equal to the volume that is pumped out each minute (the cardiac output). Because of this, the velocity of blood flow across each level of the circulatory system is primarily determined by the total
1498:
Circulatory system of species subjected to orthostatic blood pressure (such as arboreal snakes) has evolved with physiological and morphological features to overcome the circulatory disturbance. For instance, in arboreal snakes the heart is closer to the head, in comparison with aquatic snakes. This
1253:
In summary, the efficacy of ANH has been described mathematically by means of measurements of surgical blood loss and blood volume flow measurement. This form of analysis permits accurate estimation of the potential efficiency of the techniques and shows the application of measurement in the medical
416:
On the other hand, hypervolemic hemodilution (HVH) uses acute preoperative volume expansion without any blood removal. In choosing a fluid, however, it must be assured that when mixed, the remaining blood behaves in the microcirculation as in the original blood fluid, retaining all its properties of
412:
Hemodilution can be normovolemic, which implies the dilution of normal blood constituents by the use of expanders. During acute normovolemic hemodilution (ANH), blood subsequently lost during surgery contains proportionally fewer red blood cells per milliliter, thus minimizing intraoperative loss of
207:
affects the mechanics of the circulation in several ways. An alteration of the osmotic pressure difference across the membrane of a blood cell causes a shift of water and a change of cell volume. The changes in shape and flexibility affect the mechanical properties of whole blood. A change in plasma
1926:
and coming from experimental observations on blood flows, according to
Thurston, there is a plasma release-cell layering at the walls surrounding a plugged flow. It is a fluid layer in which at a distance δ, viscosity η is a function of δ written as η(δ), and these surrounding layers do not meet at
2641:
Under normal conditions, to avoid atherogenesis, thrombosis, smooth muscle proliferation and endothelial apoptosis, shear stress maintains its magnitude and direction within an acceptable range. In some cases occurring due to blood hammer, shear stress reaches larger values. While the direction of
2592:
When force is applied to a material it starts to deform or move. As the force needed to deform a material (e.g. to make a fluid flow) increases with the size of the surface of the material A., the magnitude of this force F is proportional to the area A of the portion of the surface. Therefore, the
2034:
Blood resistance varies depending on blood viscosity and its plugged flow (or sheath flow since they are complementary across the vessel section) size as well, and on the size of the vessels. Assuming steady, laminar flow in the vessel, the blood vessels behavior is similar to that of a pipe. For
2711:
The blood pressure in the circulation is principally due to the pumping action of the heart. The pumping action of the heart generates pulsatile blood flow, which is conducted into the arteries, across the micro-circulation and eventually, back via the venous system to the heart. During each
3093:
Pressure drops gradually as blood flows from the major arteries, through the arterioles, the capillaries until blood is pushed up back into the heart via the venules, the veins through the vena cava with the help of the muscles. At any given pressure drop, the flow rate is determined by the
2119:
In the arterioles blood pressure is lower than in the major arteries. This is due to bifurcations, which cause a drop in pressure. The more bifurcations, the higher the total cross-sectional area, therefore the pressure across the surface drops. This is why the arterioles have the highest
1927:
the vessel centre in real blood flow. Instead, there is the plugged flow which is hyperviscous because holding high concentration of RBCs. Thurston assembled this layer to the flow resistance to describe blood flow by means of a viscosity η(δ) and thickness δ from the wall layer.
1603:. For this reason, the blood flow velocity is the fastest in the middle of the vessel and slowest at the vessel wall. In most cases, the mean velocity is used. There are many ways to measure blood flow velocity, like videocapillary microscoping with frame-to-frame analysis, or
719:
This is based on the assumption that each unit removed by hemodilution has a volume of 450 mL (the actual volume of a unit will vary somewhat since completion of collection is dependent on weight and not volume). The model assumes that the hemodilute value is equal to the
182:
of normal human plasma at 37 °C is 1.4 mN·s/m. The viscosity of normal plasma varies with temperature in the same way as does that of its solvent water;a 3°C change in temperature in the physiological range (36.5°C to 39.5°C)reduces plasma viscosity by about 10%.
4898:
Otto CM, Stoddard M, Waggoner A, Zoghbi WA. Recommendations for
Quantification of Doppler Echocardiography: A Report from the Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. J Am Soc Echocardiogr
2803:
Differences in mean blood pressure are responsible for blood flow from one location to another in the circulation. The rate of mean blood flow depends on both blood pressure and the resistance to flow presented by the blood vessels. Mean blood pressure decreases as the
1196:
and the greater the number of units removed during hemodilution, the more effective ANH is for preventing homologous blood transfusion. The model here is designed to allow doctors to determine where ANH may be beneficial for a patient based on their knowledge of the
2687:. Friction between the fluid and the moving boundaries causes the fluid to shear (flow). The force required for this action per unit area is the stress. The relation between the stress (force) and the shear rate (flow velocity) determines the viscosity.
2127:
Immediately following the arterioles are the capillaries. Following the logic observed in the arterioles, we expect the blood pressure to be lower in the capillaries compared to the arterioles. Since pressure is a function of force per unit area,
450:
is a fluid containing particles that are large enough to exert an oncotic pressure across the micro-vascular membrane. When debating the use of colloid or crystalloid, it is imperative to think about all the components of the starling equation:
1211:. Though the model used a 70 kg patient, the result can be applied to any patient. To apply these result to any body weight, any of the values BLs, BLH and ANHH or PRBC given in the table need to be multiplied by the factor we will call T
817:
The maximum SBL that is possible when ANH is used without falling below Hm(BLH) is found by assuming that all the blood removed during ANH is returned to the patient at a rate sufficient to maintain the hematocrit at the minimum safe level
2107:
changes) with high flow rates that generate only small drops in pressure. The smaller arteries and arterioles have higher resistance, and confer the main blood pressure drop across major arteries to capillaries in the circulatory system.
343:
4771:
Markham LW, Knecht SK, Daniels SR, Mays WA, Khoury PR, Knilans TK (November 2004). "Development of exercise-induced arm-leg blood pressure gradient and abnormal arterial compliance in patients with repaired coarctation of the aorta".
4230:
Stücker, M.; Bailer, V.; Reuther, T.; Hoffman, K.; Kellam, K.; Altmeyer, P. (1996). "Capillary Blood Cell
Velocity in Human Skin Capillaries Located Perpendicularly to the Skin Surface: Measured by a New Laser Doppler Anemometer".
441:
To maintain the normovolemia, the withdrawal of autologous blood must be simultaneously replaced by a suitable hemodilute. Ideally, this is achieved by isovolemia exchange transfusion of a plasma substitute with a colloid
3149:. Blood pressure can be monitored either invasively through an inserted blood pressure transducer assembly (providing continuous monitoring), or noninvasively by repeatedly measuring the blood pressure with an inflatable
1489:
The normal human cardiac output is 5-6 L/min at rest. Not all blood that enters the left ventricle exits the heart. What is left at the end of diastole (EDV) minus the stroke volume make up the end systolic volume (ESV).
212:
alters the hematocrit, that is, the volume concentration of red cells in the whole blood by redistributing water between the intravascular and extravascular spaces. This in turn affects the mechanics of the whole blood.
4918:
4839:
Puyo, Léo, Michel Paques, Mathias Fink, José-Alain Sahel, and
Michael Atlan. "Waveform analysis of human retinal and choroidal blood flow with laser Doppler holography." Biomedical Optics Express 10, no. 10 (2019):
3657:
In normal blood, at levels of shear rate such that equation 15 is applicable, i.e., Newtonian flow, it has been shown that the temperature coefficient of viscosity is identical with that for water over the range of
3804:"Association of Primary Hemodilution and Retrograde Autologous Priming with Transfusion in Cardiac Surgery: Analysis of the Perfusion Case Database of the Japanese Society of Extra-Corporeal Technology in Medicine"
1283:
The heart is the driver of the circulatory system, pumping blood through rhythmic contraction and relaxation. The rate of blood flow out of the heart (often expressed in L/min) is known as the cardiac output (CO).
1591:
4000, is represented as turbulent flow. Due to its smaller radius and lowest velocity compared to other vessels, the
Reynolds number at the capillaries is very low, resulting in laminar instead of turbulent flow.
1144:, although five units of blood must be removed during hemodilution. Under these conditions, to achieve the maximum benefit from the technique if ANH is used, no homologous blood will be required to maintain the
3968:
2702:
Veins are described as the "capacitance vessels" of the body because over 70% of the blood volume resides in the venous system. Veins are more compliant than arteries and expand to accommodate changing volume.
1245:
2002:
1745:
1507:
Blood flow is also affected by the smoothness of the vessels, resulting in either turbulent (chaotic) or laminar (smooth) flow. Smoothness is reduced by the buildup of fatty deposits on the arterial walls.
3182:
Noninvasive hemodynamic monitoring of eye fundus vessels can be performed by Laser
Doppler holography, with near infrared light. The eye offers a unique opportunity for the non-invasive exploration of
727:
prior to surgery, therefore, the re-transfusion of blood obtained by hemodilution must begin when SBL begins. The RCM available for retransfusion after ANH (RCMm) can be calculated from the patient's
117:
rather than hydrodynamics. Because blood vessels are not rigid tubes, classic hydrodynamics and fluids mechanics based on the use of classical viscometers are not capable of explaining haemodynamics.
632:
1884:
2555:
2431:
1599:
Often expressed in cm/s. This value is inversely related to the total cross-sectional area of the blood vessel and also differs per cross-section, because in normal condition the blood flow has
662:. How much blood is to be removed is usually based on the weight, not the volume. The number of units that need to be removed to hemodilute to the maximum safe hematocrit (ANH) can be found by
2094:
1071:
2120:
pressure-drop. The pressure drop of the arterioles is the product of flow rate and resistance: ∆P=Q xresistance. The high resistance observed in the arterioles, which factor largely in the ∆
884:
3863:
1421:
1151:
if blood loss does not exceed 2940 ml. In such a case, ANH can save a maximum of 1.1 packed red blood cell unit equivalent, and homologous blood transfusion is necessary to maintain
997:
812:
1559:
424:
In presenting what volume of ANH should be applied one study suggests a mathematical model of ANH which calculates the maximum possible RCM savings using ANH, given the patients weight
2253:
714:
2927:
3214:
drive the flow of blood throughout the circulation. The rate of mean blood flow depends on both blood pressure and the hemodynamic resistance to flow presented by the blood vessels.
2635:
2483:
3090:
is 110/70 mmHg. The relatively uniform pressure in the arteries indicate that these blood vessels act as a pressure reservoir for fluids that are transported within them.
3076:
2685:
3000:
2324:
2785:
1470:
551:
413:
the whole blood. Therefore, blood lost by the patient during surgery is not actually lost by the patient, for this volume is purified and redirected into the patient.
3101:
is the difference between the blood pressure measured in the arms and that measured in the legs. It is normally less than 10 mm Hg, but may be increased in e.g.
4830:
Puyo, L., M. Paques, M. Fink, J-A. Sahel, and M. Atlan. "In vivo laser
Doppler holography of the human retina." Biomedical optics express 9, no. 9 (2018): 4113-4129.
254:
166:. The presence of these formed elements and their interaction with plasma molecules are the main reasons why blood differs so much from ideal Newtonian fluids.
3444:
2493:
For the thin-walled assumption to be valid the vessel must have a wall thickness of no more than about one-tenth (often cited as one twentieth) of its radius.
33:
1158:, even if ANH is used. This model can be used to identify when ANH may be used for a given patient and the degree of ANH necessary to maximize that benefit.
1311:. The micro-circulation — the arterioles, capillaries, and venules —constitutes most of the area of the vascular system and is the site of the transfer of O
4598:
Tazraei, P.; Riasi, A.; Takabi, B. (2015). "The influence of the non-Newtonian properties of blood on blood-hammer through the posterior cerebral artery".
5551:
2642:
the stress may also change by the reverse flow, depending on the hemodynamic conditions. Therefore, this situation can lead to atherosclerosis disease.
5411:
4686:
3210:
by high-contrast measurement of
Doppler responses from endoluminal blood flow profiles in vessels in the posterior segment of the eye. Differences in
1331:
and other gaseous wastes exchanged and expelled during breathing. Blood then returns to the left side of the heart where it begins the process again.
648:(initial hematocrit) is the patient's initial hematocrit. From the equation above it is clear that the volume of blood removed during the ANH to the
1511:
The
Reynolds number (denoted NR or Re) is a relationship that helps determine the behavior of a fluid in a tube, in this case blood in the vessel.
1627:), which is equal to the difference between the peak systolic velocity and the minimum diastolic velocity divided by the mean velocity during the
1425:
The other thermodilution method is to sense the temperature change from a liquid injected in the proximal port of a Swan-Ganz to the distal port.
3859:
203:
molecules per liter of that substance and at 0 °C it has an osmotic pressure of 2.27 MPa (22.4 atm). The osmotic pressure of the
1168:
is 0.30 or less it is not possible to save a red cell mass equivalent to two units of homologous PRBC even if the patient is hemodiluted to an
3745:"Evaluation of Acute Normovolemic Hemodilution and Autotransfusion in Neurosurgical Patients Undergoing Excision of Intracranial Meningioma"
2504:
exerted circumferentially (perpendicular both to the axis and to the radius of the object) in the cylinder wall, and can be described as:
2597:
at the wall that is associated with blood flow through an artery depends on the artery size and geometry and can range between 0.5 and 4
2820:
losses of energy. Mean blood pressure drops over the whole circulation, although most of the fall occurs along the small arteries and
1936:
397:
Hemodilution is the dilution of the concentration of red blood cells and plasma constituents by partially substituting the blood with
237:. It is true that in a steady state flow of a viscous fluid through a rigid spherical body immersed in the fluid, where we assume the
67:. The hemodynamic response continuously monitors and adjusts to conditions in the body and its environment. Hemodynamics explains the
5774:
1637:
1093:
The model used assumes ANH used for a 70 kg patient with an estimated blood volume of 70 ml/kg (4900 ml). A range of
4914:
Claude Franceschi; Paolo Zamboni Principles of Venous Hemodynamics Nova Science Publishers 2009-01 ISBN Nr 1606924850/9781606924853
1217:
245:
force of the particle is balanced by the viscous drag force. From this force balance the speed of fall can be shown to be given by
6046:
5544:
2174:" drugs decreased the viscosity of blood, but instead studies found that they act by reducing the tendency of the blood to clot.
2124:
is a result of a smaller radius of about 30 μm. The smaller the radius of a tube, the larger the resistance to fluid flow.
5404:
3467:
2166:
concentration) reduces viscosity, whereas increased red blood cell concentration increases viscosity. It had been thought that
6148:
4752:
4670:
4642:
4542:
4437:
4407:
4321:
4154:
3905:
3727:
3564:
3539:
3507:
4850:
562:
4275:
4214:
1830:
2510:
2386:
4987:
6153:
5537:
5298:
4351:"Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradient is known"
4002:
2041:
3743:
Naqash, Imtiaz A.; Draboo, M. A.; Lone, Abdul Qayoom; Nengroo, Showkat H.; Kirmani, Altaf; Bhat, Abdul Rashid (2011).
1008:
5397:
4890:
Siderman S, Beyar R, Kleber AG. Cardiac Electrophysiology, Circulation and Transport. Kluwer Academic Publishers 1991
824:
4339:
GB Thurston, Viscosity and viscoelasticity of blood in small diameter tubes, Microvasular Research 11, 133 146, 1976
3156:
Hypertension is diagnosed by the presence of arterial blood pressures of 140/90 or greater for two clinical visits.
6168:
5266:
3802:
Saito, Chihiro; Kamei, Tetsuya; Kubota, Shoji; Yoshida, Kiyoshi; Hibiya, Makoto; Hashimoto, Shuji (December 2018).
3676:
3159:
Pulmonary Artery Wedge Pressure can show if there is congestive heart failure, mitral and aortic valve disorders,
1343:
931:
4943:
1904:: length of tube. In the case of vessels with infinitely long lengths, l is replaced with diameter of the vessel.
1323:
into the cells. The venous system returns the de-oxygenated blood to the right heart where it is pumped into the
747:
4050:
Nasoori, Alireza; Taghipour, Ali; Shahbazzadeh, Delavar; Aminirissehei, Abdolhossein; Moghaddam, Sharif (2014).
1520:
120:
The study of the blood flow is called hemodynamics, and the study of the properties of the blood flow is called
2182:
668:
2841:
1175:
of 0.15. That is because from the RCM equation the patient RCM falls short from the equation giving above. If
1136:
is assumed to be 0.25.then from the equation above the RCM count is still high and ANH is not necessary, if BL
5687:
1821:
4690:
2607:
6158:
6064:
5819:
5797:
4911:
Claude Franceschi L'investigation vasculaire par ultrasonographie Doppler Masson 1979 ISBN Nr 2-225-63679-6
4266:
Tortora, Gerard J.; Derrickson, Bryan (2012). "The Cardiovascular System: Blood Vessels and Hemodynamics".
4205:
Tortora, Gerard J.; Derrickson, Bryan (2012). "The Cardiovascular System: Blood Vessels and Hemodynamics".
2697:
1291:, the largest artery of the body. It then proceeds to divide into smaller and smaller arteries, then into
6059:
5804:
4530:
3019:
2460:
2158:
If the blood viscosity increases (gets thicker), the result is an increase in arterial pressure. Certain
3997:. Board Review Series (3rd ed.). Philadelphia: Lippincott Williams & Wilkins. pp. 73–113.
2177:
To determine the systemic vascular resistance (SVR) the formula for calculating all resistance is used.
556:
To identify the minimum safe hematocrit desirable for a given patient the following equation is useful:
5885:
3032:
2652:
2373:
17:
4052:"Heart place and tail length evaluation in Naja oxiana, Macrovipera lebetina, and Montivipera latifii"
2938:
2571:
exerted circumferentially on an area of the cylinder wall that has the following two lengths as sides:
2262:
6089:
6036:
5912:
5892:
5856:
5779:
5739:
5560:
4887:
Braunwald E (Editor). Heart Disease: A Textbook of Cardiovascular Medicine. 5th Ed. W.B.Saunders 1997
4170:
Fung, Yuan-cheng; Zweifach, B.W. (1971). "Microcirculation: Mechanics of Blood Flow in Capillaries".
3930:
3482:
1604:
2729:
2099:
The larger arteries, including all large enough to see without magnification, are conduits with low
1923:
1434:
6143:
5907:
5897:
5787:
4298:
3102:
1115:
The result of the model calculations are presented in a table given in the appendix for a range of
378:
of the particle depends on the square of the radius. If the particle is released from rest in the
6173:
6094:
6026:
5971:
5872:
5792:
5676:
5654:
5448:
5373:
4980:
4861:
3183:
2376:(assuming that the thickness of the vessel wall is very small as compared to the diameter of the
5672:
2835:
The relationship between pressure, flow, and resistance is expressed in the following equation:
2035:
instance if p1 and p2 are pressures are at the ends of the tube, the pressure drop/gradient is:
1250:
Basically, the model considered above is designed to predict the maximum RCM that can save ANH.
6031:
6021:
5935:
5681:
5639:
5634:
3487:
3472:
3171:
3015:
RAP = right atrial pressure (in mmHg), the average pressure of blood as it returns to the heart
2721:
2115:
Illustration demonstrating how vessel narrowing, or vasoconstriction, increases blood pressure.
1107:
was evaluated to understand conditions where hemodilution is necessary to benefit the patient.
1083:
is the red cell mass that would have to be administered using homologous blood to maintain the
457:
375:
4926:
B Bo Sramek: Systemic Hemodynamics and Hemodynamic Management, 4th Edition, ESBN 1-59196-046-0
389:
increases until it attains the steady value called the terminal velocity (U), as shown above.
5880:
5496:
5161:
5129:
3631:
3497:
3187:
3175:
3138:
191:
The osmotic pressure of solution is determined by the number of particles present and by the
3012:
MAP = mean arterial pressure (in mmHg), the average pressure of blood as it leaves the heart
338:{\displaystyle U_{s}={\frac {2}{9}}{\frac {\left(\rho _{p}-\rho _{f}\right)}{\mu }}g\,a^{2}}
5629:
5612:
5331:
5326:
5283:
5233:
5124:
5103:
4179:
3427:
2832:, and pumping from contraction of skeletal muscles also influence blood pressure in veins.
5529:
3581:
3244:
Maximum Blood Loss Possible When ANH Is Used Before Homologous Blood Transfusion Is Needed
896:
there will not be any need for blood transfusion. We can conclude from the foregoing that
106:
and temperature of the whole body, and the protection from microbial and mechanical harm.
8:
5976:
5814:
5809:
5644:
5617:
5501:
5486:
5458:
5288:
5256:
5098:
5066:
3150:
3086:
2100:
1812:
110:
4191:
4183:
6084:
5949:
5702:
5506:
5316:
5308:
5293:
5261:
5241:
5149:
4973:
4580:
4375:
4350:
4285:
4117:
4092:
4091:
Lillywhite, Harvey B.; Albert, James S.; Sheehy, Coleman M.; Seymour, Roger S. (2012).
3960:
3911:
3836:
3803:
3779:
3744:
3492:
3477:
3412:
3191:
3123:
2805:
2713:
2159:
1612:
1276:
1272:
1122:
from 0.30 to 0.50 with ANH performed to minimum hematocrits from 0.30 to 0.15. Given a
226:
178:
behaves like a Newtonian fluid at physiological rates of shear. Typical values for the
48:
4563:
Potters (13 February 2014). "Measuring Wall Shear Stress Using Velocity-Encoded MRI".
4471:
4454:
4068:
4051:
3690:
3671:
3555:
Fieldman, Joel S.; Phong, Duong H.; Saint-Aubin, Yvan; Vinet, Luc (2007). "Rheology".
3530:
Tortora, Gerard J.; Derrickson, Bryan (2012). "The Cardiovascular System: The Blood".
1267:
5720:
5692:
5353:
4789:
4748:
4720:
4666:
4638:
4615:
4538:
4529:
Naderi, Nasim (2022-01-01), Maleki, Majid; Alizadehasl, Azin; Haghjoo, Majid (eds.),
4506:
4476:
4433:
4403:
4380:
4317:
4271:
4248:
4210:
4150:
4122:
4073:
4027:
3998:
3952:
3947:
3901:
3841:
3823:
3784:
3766:
3723:
3695:
3648:
3604:
3560:
3535:
3502:
3026:
A simplified form of this equation assumes right atrial pressure is approximately 0:
406:
60:
4807:
4584:
3964:
3915:
3126:
with integrated systems for monitoring of several hemodynamic parameters, including
6069:
5664:
5453:
5273:
5139:
5025:
4957:
4781:
4607:
4572:
4466:
4370:
4366:
4362:
4312:
Marieb, Elaine N.; Hoehn, Katja (2013). "The Cardiovascular System:Blood Vessels".
4240:
4187:
4112:
4104:
4063:
3942:
3893:
3860:"Efficacy of Acute Normovolemic hemodilution, Accessed as a Function of Blood lost"
3831:
3815:
3774:
3756:
3685:
3640:
3596:
3352:
3207:
3118:
1320:
443:
209:
159:
103:
4785:
3644:
5919:
5649:
5511:
5341:
5321:
3082:
2497:
2486:
2377:
2361:
2144:
2111:
2104:
1817:
Resistance is also related to vessel radius, vessel length, and blood viscosity.
402:
4865:
3600:
1182:
is 0.40 one must remove at least 7.5 units of blood during ANH, resulting in an
6163:
6079:
6004:
5996:
5590:
5577:
5481:
5443:
5363:
5358:
5278:
4905:
4712:
4498:
4108:
4019:
3897:
3462:
3457:
3432:
3211:
3142:
3127:
2163:
374:
is the gravitational acceleration. From the above equation we can see that the
246:
222:
163:
91:
64:
56:
40:
4919:
Venous Insufficiency of the pelvis and lower extremities-Hemodynamic Rationale
4611:
4576:
3270:
Maximum blood loss without ANH before homologous blood transfusion is required
1338:
Cardiac output is determined by two methods. One is to use the Fick equation:
6137:
5697:
5607:
5600:
5585:
5246:
5059:
3888:
Kaya, M.; Li, J.K.-J. (2001). "Hemodilution: Modeling and clinical aspects".
3827:
3819:
3770:
3417:
3166:
2825:
2598:
2171:
2152:
1628:
405:. It is a strategy to avoid exposure of patients to the potential hazards of
242:
230:
4902:
Peterson LH, The Dynamics of Pulsatile Blood Flow, Circ. Res. 1954;2;127-139
3761:
3557:
Biology and Mechanics of Blood Flows, Part II: Mechanics and Medical Aspects
2348:
Normal systemic vascular resistance is between 900 and 1440 dynes/sec/cm−5.
2155:) increase the size of blood vessels, thereby decreasing arterial pressure.
6111:
6101:
6074:
5751:
5725:
5389:
5348:
5178:
5154:
5144:
5049:
5030:
4793:
4724:
4619:
4510:
4480:
4384:
4244:
4126:
4077:
4031:
3929:
Feldman, Jeffrey M.; Roth, Jonathan V.; Bjoraker, David G. (January 1995).
3845:
3788:
3699:
3672:"Blood viscosity and blood pressure: role of temperature and hyperglycemia"
3608:
3452:
3160:
2594:
2369:
1930:
The blood resistance law appears as R adapted to blood flow profile :
1751:
Relation between blood flow velocity and total cross-section area in human
1600:
204:
175:
143:
121:
72:
68:
4252:
3956:
3652:
2720:) pressure. In physiology, these are often simplified into one value, the
147:
6116:
6106:
5834:
5829:
5824:
5735:
5336:
5202:
5083:
5078:
5054:
4049:
3206:-shaped profile with time This technique enables non invasive functional
2813:
2593:
quantity (F/A) that is the force per unit area is called the stress. The
2356:
2148:
2147:
can reduce the size of blood vessels, thereby increasing blood pressure.
1308:
1304:
1296:
192:
52:
3525:
3523:
2799:
PP = Pulse pressure which is systolic pressure minus diastolic pressure.
1140:
does not exceed 2303 ml, since the hemotocrit will not fall below H
6054:
5839:
5729:
5712:
5595:
5470:
5424:
5368:
5211:
5207:
5183:
5112:
5093:
3146:
3131:
1292:
95:
4149:(Sixth ed.). New Jersey: John Wiley &Sons, Inc. p. 725.
2712:
heartbeat, systemic arterial blood pressure varies between a maximum (
1428:
Cardiac output is mathematically expressed by the following equation:
1303:, and the blood then travels back through the network of veins to the
5986:
5757:
5624:
5420:
5223:
5166:
5088:
5015:
4996:
4884:
Rowell LB. Human Cardiovascular Control. Oxford University press 1993
3520:
2829:
2821:
2817:
2717:
2021:
418:
234:
179:
4908:, Bigatello LM, George E., Minerva Anestesiol, 2002 Apr;68(4):219-25
6014:
5745:
5518:
5432:
5378:
5173:
5134:
5119:
5042:
5020:
4936:
4635:
Hemodynamic Monitoring: Evolving technologies and clinical practice
4453:
Rosenson RS, Wolff D, Green D, Boss AH, Kensey KR (February 2004).
4093:"Gravity and the evolution of cardiopulmonary morphology in snakes"
1616:
1608:
155:
151:
114:
79:
6009:
5251:
5216:
5196:
5073:
5010:
3199:
2167:
2162:
can change the viscosity of the blood. For instance, anemia (low
1316:
1300:
447:
398:
238:
83:
3141:
is the observation of hemodynamic parameters over time, such as
2645:
1997:{\displaystyle R={\frac {cL\eta (\delta )}{(\pi \delta r^{3})}}}
1514:
The equation for this dimensionless relationship is written as:
1189:
of 0.20 to save two units equivalence. Clearly, the greater the
5849:
5844:
4893:
4881:
Berne RM, Levy MN. Cardiovascular physiology. 7th Ed Mosby 1997
4855:
4637:(1 ed.). St. Louis, Missouri: Elsevier Mosby. p. 25.
3195:
1740:{\displaystyle PI={\frac {v_{systole}-v_{diastole}}{v_{mean}}}}
1578:: characteristic dimension of the vessel, in this case diameter
241:
is negligible in such a flow, it is believed that the downward
87:
3361:
225:
is highly flexible and biconcave in shape. Its membrane has a
5981:
5568:
4090:
3718:
Caro, C.G.; Pedley, T.J.; Schroter, R.C.; Seed, W.A. (1978).
3554:
3436:
3203:
2809:
2568:
2501:
1324:
1288:
1240:{\displaystyle T={\frac {\text{patient's weight in kg}}{70}}}
638:
379:
139:
133:
4965:
3670:
Cinar, Yildirim; Senyol, A. Mete; Duman, Kamber (May 2001).
5559:
4229:
3582:"Human blood under normothermic and hypothermic conditions"
3403:
3373:
3367:
1299:, where oxygen transfer occurs. The capillaries connect to
3931:"maximum blood savings by acute Normovolemic hemodilution"
3862:. the journal of American society of anesthsiologist inc.
3534:(13th ed.). John Wiley & Sons. pp. 729–732.
3167:
Remote, indirect monitoring of blood flow by laser Doppler
2345:
To get this in Wood units the answer is multiplied by 80.
195:. For example, a 1 molar solution of a substance contains
4144:
3388:
3382:
1820:
In a first approach based on fluids, as indicated by the
4770:
4455:"Aspirin. Aspirin does not alter native blood viscosity"
3801:
3742:
3629:
Errill, Edward W. (October 1969). "Rheology of Blood".
99:
4452:
3717:
627:{\displaystyle \ BL_{s}=EBV\ln {\frac {H_{i}}{H_{m}}}}
4923:
WR Milnor: Hemodynamics, Williams & Wilkins, 1982
4747:. Lippincott Williams & Wilkins. pp. 93–94.
4270:(13th ed.). John Wiley & Sons. p. 817.
4209:(13th ed.). John Wiley & Sons. p. 816.
3394:
3391:
3379:
3355:
3035:
2941:
2844:
2828:
forces (e.g., during standing), and valves in veins,
2732:
2655:
2610:
2528:
2513:
2463:
2404:
2389:
2368:
Regardless of site, blood pressure is related to the
2265:
2185:
2044:
1939:
1879:{\displaystyle \Delta P={\frac {8\mu lQ}{\pi r^{4}}}}
1833:
1640:
1631:. This value decreases with distance from the heart.
1523:
1437:
1346:
1287:
Blood being pumped out of the heart first enters the
1220:
1011:
934:
827:
750:
671:
565:
460:
257:
4145:
Munson BR, Young DF, Okiishi TH, Huebsch WW (2009).
3370:
2550:{\displaystyle \sigma _{\theta }={\dfrac {F}{tl}}\ }
2426:{\displaystyle \sigma _{\theta }={\dfrac {Pr}{t}}\ }
3928:
3722:. Oxford University Press. pp. 3–60, 151–176.
3400:
3385:
3376:
3364:
3358:
1619:. One parameter to quantify this difference is the
4597:
4169:
4140:
4138:
4136:
3070:
2994:
2921:
2779:
2679:
2629:
2549:
2477:
2425:
2318:
2247:
2088:
1996:
1878:
1739:
1553:
1464:
1415:
1239:
1065:
991:
918:therefore is the incremental surgical blood loss (
878:
806:
708:
626:
545:
337:
4736:
4265:
4204:
4198:
3883:
3881:
3529:
2474:
2089:{\displaystyle {\frac {p_{1}-p_{2}}{l}}=\Delta P}
2024:of blood in the wall plasma release-cell layering
641:volume; 70 mL/kg was used in this model and
6135:
4423:
4421:
4419:
4316:(9th ed.). Pearson Education. p. 712.
3749:Journal of Anaesthesiology Clinical Pharmacology
3713:
3711:
3709:
3669:
2932:When applied to the circulatory system, we get:
1204:, the potential for SBL, and an estimate of the
1066:{\displaystyle {RCM_{i}}={BL_{i}}\times {H_{m}}}
366:are the respectively particle and fluid density
154:and 1.5% other solutes. The formed elements are
4719:, Treasure Island (FL): StatPearls Publishing,
4505:, Treasure Island (FL): StatPearls Publishing,
4133:
4026:, Treasure Island (FL): StatPearls Publishing,
3443:syllable is variously written according to the
3282:Haematocrit Always Expressed Here As A Fraction
2332:SVR = systemic vascular resistance (mmHg/L/min)
879:{\displaystyle BL_{H}={\frac {RCM_{H}}{H_{m}}}}
4660:
3878:
3340:
1090:if ANH is not used and blood loss equals BLH.
889:If ANH is used as long as SBL does not exceed
5545:
5405:
4981:
4689:. Health and Life. 2010-06-07. Archived from
4416:
4335:
4333:
3706:
3321:Cell Mass Available For Transfusion after ANH
3306:Packed Red Blood Cell Equivalent Saved by ANH
2030:δ = distance in the plasma release-cell layer
1271:Diagram of the circulatory system. SVC/IVC -
186:
5419:
4808:"RHC | Vanderbilt University Medical Center"
4499:"Physiology, Peripheral Vascular Resistance"
4496:
4348:
3890:Hemodilution:Modelling and clinincal Aspects
3253:Incremental Blood Loss Possible with ANH.(BL
1922:In a second approach, more realistic of the
1416:{\displaystyle CO=VO2/C_{a}O_{2}-C_{v}O_{2}}
992:{\displaystyle \ {BL_{i}}={BL_{H}}-{BL_{s}}}
734:and the final hematocrit after hemodilution(
4710:
4311:
2649:Laminar shear of fluid between two plates.
807:{\displaystyle RCM=EVB\times (H_{i}-H_{m})}
94:throughout the body to maintain cell-level
5552:
5538:
5412:
5398:
4988:
4974:
4766:
4764:
4330:
4056:Asian Pacific Journal of Tropical Medicine
4017:
1554:{\displaystyle NR={\frac {\rho vL}{\mu }}}
1499:facilitates blood perfusion to the brain.
4470:
4374:
4116:
4067:
3946:
3835:
3808:The Journal of Extra-corporeal Technology
3778:
3760:
3689:
2248:{\displaystyle R=(\Delta pressure)/flow.}
709:{\displaystyle ANH={\frac {BL_{s}}{450}}}
324:
78:Blood flow ensures the transportation of
4742:
4497:Delong, Claire; Sharma, Sandeep (2022),
3992:
3170:
3117:
3108:
2922:{\displaystyle Flow=Pressure/Resistance}
2644:
2355:
2110:
1266:
113:, and is most efficiently studied using
5561:Physiology of the cardiovascular system
4761:
4656:
4654:
4562:
4492:
4490:
4097:Comparative Biochemistry and Physiology
4018:King, Jordan; Lowery, David R. (2022),
3892:. Vol. 1. IEEE. pp. 177–179.
3514:
2577:is the radial thickness of the cylinder
14:
6136:
4711:DeMers, Daniel; Wachs, Daliah (2022),
4565:Current Cardiovascular Imaging Reports
4528:
4397:
4268:Principles of Anatomy & Physiology
4207:Principles of Anatomy & Physiology
3988:
3986:
3887:
3628:
3532:Principles of Anatomy & Physiology
3468:Cardiovascular System Dynamics Society
3113:
2630:{\displaystyle \sigma ={\frac {F}{A}}}
1910:: flow rate of the blood in the vessel
1806:
1493:
169:
150:. The plasma contains 91.5% water, 7%
5533:
5393:
4969:
4632:
4535:Practical Cardiology (Second Edition)
3971:from the original on 23 February 2022
3622:
3508:Functional near-infrared spectroscopy
3276:Estimated Blood Volume(70 mL/kg)
2824:. Gravity affects blood pressure via
2455:is the inside radius of the cylinder.
71:that govern the flow of blood in the
4713:"Physiology, Mean Arterial Pressure"
4687:"Normal Blood Pressure Range Adults"
4665:. Oxford : Oxford University Press.
4651:
4487:
4427:
3579:
3421:(which comes from the ancient Greek
3202:, whose Doppler responses exhibit a
2338:CVP = central venous pressure (mmHg)
2335:MAP = mean arterial pressure (mmHg)
1335:cross-sectional area of that level.
4432:. New York: Springer. p. 571.
4192:10.1146/annurev.fl.03.010171.001201
3983:
2583:is the axial length of the cylinder
2478:{\displaystyle \sigma _{\theta }\!}
1002:When expressed in terms of the RCM
24:
5299:Fluorescence in situ hybridization
4745:Cardiovascular Physiology Concepts
2724:, which is calculated as follows:
2195:
2080:
1834:
216:
25:
6185:
4930:
4472:10.1111/j.1538-79333.2004.0615f.x
3866:from the original on 29 June 2012
3099:arm–leg (blood pressure) gradient
3071:{\displaystyle CO\approx MAP/TPR}
2706:
2680:{\displaystyle v=u,\tau =\sigma }
1262:
5267:Oral and maxillofacial pathology
4663:The Mechanics of The Circulation
4531:"Chapter 11 - Hemodynamic Study"
4400:Principles of Medical Physiology
4172:Annual Review of Fluid Mechanics
3948:10.1097/00000539-199501000-00019
3677:American Journal of Hypertension
3351:
3163:, shunts, or cardiac tamponade.
3081:The ideal blood pressure in the
2995:{\displaystyle CO=(MAP-RAP)/TPR}
2319:{\displaystyle SVR=(MAP-CVP)/CO}
2014:c = constant coefficient of flow
1801:
1789:Vena cavae inferior and superior
4875:
4843:
4833:
4824:
4800:
4704:
4679:
4626:
4591:
4556:
4522:
4446:
4391:
4342:
4305:
4259:
4223:
4163:
4147:Fundamentals of Fluid Mechanics
4084:
4043:
4011:
3922:
3226:Acute Normovolemic Hemodilution
2372:of the vessel according to the
2351:
392:
4537:, Elsevier, pp. 201–216,
4402:. India: vistasta Publishing.
4367:10.1113/jphysiol.1955.sp005276
4314:Human anatomy & physiology
3852:
3795:
3736:
3663:
3573:
3559:. Springer. pp. 119–123.
3548:
3194:can measure blood flow in the
3009:CO = cardiac output (in L/min)
2975:
2951:
2780:{\displaystyle MAP=DP+1/3(PP)}
2774:
2765:
2691:
2302:
2278:
2257:This translates for SVR into:
2222:
2192:
2027:r = radius of the blood vessel
1988:
1969:
1964:
1958:
1824:. The equation is as follows:
1465:{\displaystyle CO=SV\times HR}
801:
775:
540:
537:
511:
502:
476:
473:
13:
1:
5688:Aortic valve area calculation
4995:
4786:10.1016/j.amjcard.2004.07.097
4069:10.1016/S1995-7645(14)60220-0
3691:10.1016/S0895-7061(00)01260-7
3645:10.1152/physrev.1969.49.4.863
3589:Journal of Applied Physiology
2796:DP = Diastolic blood pressure
1502:
1257:
904:. The difference between the
382:, its sedimentation velocity
6149:Computational fluid dynamics
4020:"Physiology, Cardiac Output"
3720:The Mechanics of Circulation
2793:MAP = Mean Arterial Pressure
2722:mean arterial pressure (MAP)
2698:Capacitance of blood vessels
2011:R = resistance to blood flow
1572:: mean velocity of the blood
900:should therefore not exceed
86:, metabolic waste products,
7:
5805:Effective refractory period
5684:) / End-diastolic dimension
3993:Costanzo, Linda S. (2003).
3601:10.1152/jappl.1964.19.1.117
3580:Rand, Peter (31 May 1963).
3341:Etymology and pronunciation
3217:
3020:total peripheral resistance
2341:CO = cardiac output (L/min)
1594:
1479:CO = cardiac output (L/sec)
1327:to become oxygenated and CO
925:) possible when using ANH.
637:where EBV is the estimated
138:Blood is a complex liquid.
10:
6190:
4894:American Heart Association
4743:Klabunde, Richard (2005).
4633:Lough, Mary (2015-04-15).
4398:Sircar, Sabyasach (2008).
4109:10.1016/j.cbpa.2011.10.029
3935:Anesthesia & Analgesia
3898:10.1109/IEMBS.2001.1018881
3330:Red Cell Mass Saved by ANH
3235:Number of Units During ANH
3178:reveals retinal blood flow
2695:
2500:, in turn, is the average
1810:
229:in the region of 106
187:Osmotic pressure of plasma
131:
6154:Cardiovascular physiology
6090:Tubuloglomerular feedback
6045:
6037:Critical closing pressure
5995:
5962:
5948:
5928:
5865:
5857:Hexaxial reference system
5780:Cardiac electrophysiology
5767:
5711:
5663:
5576:
5567:
5469:
5431:
5307:
5232:
5003:
4958:Resources in your library
4612:10.1016/j.mbs.2015.03.013
4577:10.1007/s12410-014-9257-1
4428:Fung, Yuan-cheng (1997).
3483:Hemodynamics of the aorta
2587:
1822:Hagen–Poiseuille equation
1759:Total cross-section area
1110:
546:{\displaystyle \ Q=K(S-)}
6065:Renin–angiotensin system
4600:Mathematical Biosciences
4430:Biomechanics:Circulation
3300:Minimum Safe Haematocrit
3103:coarctation of the aorta
2017:L = length of the vessel
1892:: pressure drop/gradient
1605:laser Doppler anemometry
370:is the fluid viscosity,
352:is the particle radius,
127:
98:, the regulation of the
6169:Mathematics in medicine
6095:Cerebral autoregulation
6060:Kinin–kallikrein system
6027:Jugular venous pressure
5677:End-diastolic dimension
5655:Pressure volume diagram
5374:Microbiological culture
5004:Principles of pathology
4862:Oxford University Press
4661:Caro, Colin G. (1978).
3762:10.4103/0970-9185.76645
3184:cardiovascular diseases
1762:Blood velocity in cm/s
1601:laminar characteristics
1482:SV = stroke volume (ml)
6032:Portal venous pressure
6022:Mean arterial pressure
5936:Ventricular remodeling
5682:End-systolic dimension
5640:Cardiac function curve
4906:Hemodynamic Monitoring
4245:10.1006/mvre.1996.0054
4233:Microvascular Research
3820:10.1051/ject/201850231
3488:Impedance cardiography
3473:Electrical cardiometry
3179:
3134:
3072:
2996:
2923:
2781:
2688:
2681:
2631:
2551:
2479:
2427:
2374:Young–Laplace equation
2365:
2320:
2249:
2116:
2103:(assuming no advanced
2090:
1998:
1916:: radius of the vessel
1880:
1756:Type of blood vessels
1741:
1607:. Blood velocities in
1566:: density of the blood
1555:
1466:
1417:
1280:
1241:
1230:patient's weight in kg
1067:
993:
880:
808:
710:
628:
547:
376:sedimentation velocity
339:
27:Dynamics of blood flow
5673:Fractional shortening
5337:Diagnostic immunology
5162:Programmed cell death
5130:Liquefactive necrosis
4858:UK English Dictionary
4355:Journal of Physiology
4349:Womersley JR (1955).
3632:Physiological Reviews
3498:Laser Doppler imaging
3425:, meaning blood) and
3188:Laser Doppler imaging
3176:Laser Doppler imaging
3174:
3121:
3109:Clinical significance
3073:
2997:
2924:
2812:through arteries and
2782:
2682:
2648:
2632:
2552:
2480:
2449:is the wall thickness
2443:is the blood pressure
2428:
2359:
2321:
2250:
2114:
2091:
1999:
1881:
1742:
1556:
1485:HR = heart rate (bpm)
1467:
1418:
1270:
1242:
1068:
994:
881:
809:
711:
629:
548:
340:
5613:End-diastolic volume
5332:Medical microbiology
5327:Transfusion medicine
5284:Immunohistochemistry
5234:Anatomical pathology
5125:Coagulative necrosis
3515:Notes and references
3439:". The vowel of the
3087:blood pressure cuffs
3033:
2939:
2842:
2808:moves away from the
2730:
2653:
2608:
2511:
2461:
2387:
2263:
2183:
2042:
1937:
1831:
1638:
1584:: viscosity of blood
1521:
1435:
1344:
1218:
1009:
932:
825:
748:
669:
563:
458:
409:blood transfusions.
255:
6159:Exercise physiology
5977:Vascular resistance
5815:Electrocardiography
5810:Pacemaker potential
5740:Conduction velocity
5645:Venous return curve
5618:End-systolic volume
5289:Electron microscopy
5257:Molecular pathology
5135:Gangrenous necrosis
5067:Cellular adaptation
4184:1971AnRFM...3..189F
3336:Surgical Blood Loss
3291:Initial Haematocrit
3151:blood pressure cuff
3114:Pressure monitoring
2101:vascular resistance
1924:vascular resistance
1813:Vascular resistance
1807:Vascular resistance
1752:
1494:Anatomical features
655:is the same as the
170:Viscosity of plasma
111:non-Newtonian fluid
6085:Myogenic mechanism
5703:Left atrial volume
5635:Frank–Starling law
5317:Clinical chemistry
5309:Clinical pathology
5294:Immunofluorescence
5262:Forensic pathology
5242:Surgical pathology
5150:Fibrinoid necrosis
4937:Learn hemodynamics
4917:Claude Franceschi
4459:J. Thromb. Haemost
4293:Unknown parameter
3493:Photoplethysmogram
3478:Esophogeal doppler
3192:digital holography
3180:
3135:
3124:anesthetic machine
3068:
2992:
2919:
2777:
2689:
2677:
2627:
2547:
2542:
2475:
2423:
2418:
2366:
2316:
2245:
2160:medical conditions
2143:Substances called
2117:
2086:
1994:
1876:
1750:
1737:
1611:are higher during
1551:
1462:
1413:
1281:
1237:
1063:
989:
876:
804:
706:
624:
543:
335:
63:are controlled by
61:hydraulic circuits
49:circulatory system
6131:
6130:
6127:
6126:
5944:
5943:
5784:Action potential
5775:Conduction system
5721:Cardiac pacemaker
5693:Ejection fraction
5527:
5526:
5387:
5386:
5354:Mass spectrometry
4944:Library resources
4812:medsites.vumc.org
4754:978-0-7817-5030-1
4672:978-0-19-263323-1
4644:978-0-323-08512-0
4544:978-0-323-80915-3
4439:978-0-387-94384-8
4409:978-1-58890-572-7
4323:978-0-321-74326-8
4156:978-0-470-26284-9
3907:978-0-7803-7211-5
3729:978-0-19-263323-1
3566:978-0-387-74848-1
3541:978-0-470-56510-0
3503:Windkessel effect
3085:, where standard
3022:(in mmHg * min/L)
2806:circulating blood
2716:) and a minimum (
2625:
2546:
2541:
2489:or "hoop stress".
2422:
2417:
2075:
1992:
1874:
1799:
1798:
1781:4500–6000 cm
1735:
1621:pulsatility index
1549:
1321:enzyme substrates
1295:, and eventually
1235:
1231:
937:
874:
704:
622:
568:
463:
319:
279:
160:white blood cells
51:is controlled by
16:(Redirected from
6181:
6070:Vasoconstrictors
6047:Regulation of BP
5960:
5959:
5893:pulmonary artery
5866:Chamber pressure
5574:
5573:
5554:
5547:
5540:
5531:
5530:
5414:
5407:
5400:
5391:
5390:
5274:Gross processing
5140:Caseous necrosis
4990:
4983:
4976:
4967:
4966:
4870:
4869:
4864:. Archived from
4847:
4841:
4837:
4831:
4828:
4822:
4821:
4819:
4818:
4804:
4798:
4797:
4780:(9): 1200–1202.
4768:
4759:
4758:
4740:
4734:
4733:
4732:
4731:
4708:
4702:
4701:
4699:
4698:
4683:
4677:
4676:
4658:
4649:
4648:
4630:
4624:
4623:
4595:
4589:
4588:
4560:
4554:
4553:
4552:
4551:
4526:
4520:
4519:
4518:
4517:
4494:
4485:
4484:
4474:
4450:
4444:
4443:
4425:
4414:
4413:
4395:
4389:
4388:
4378:
4346:
4340:
4337:
4328:
4327:
4309:
4303:
4302:
4296:
4291:
4289:
4281:
4277:978-0470-56510-0
4263:
4257:
4256:
4227:
4221:
4220:
4216:978-0470-56510-0
4202:
4196:
4195:
4167:
4161:
4160:
4142:
4131:
4130:
4120:
4088:
4082:
4081:
4071:
4047:
4041:
4040:
4039:
4038:
4015:
4009:
4008:
3990:
3981:
3980:
3978:
3976:
3950:
3926:
3920:
3919:
3885:
3876:
3875:
3873:
3871:
3856:
3850:
3849:
3839:
3799:
3793:
3792:
3782:
3764:
3740:
3734:
3733:
3715:
3704:
3703:
3693:
3667:
3661:
3660:
3626:
3620:
3619:
3617:
3615:
3586:
3577:
3571:
3570:
3552:
3546:
3545:
3527:
3410:
3409:
3406:
3405:
3402:
3397:
3396:
3393:
3390:
3387:
3384:
3381:
3378:
3375:
3372:
3369:
3366:
3363:
3360:
3357:
3208:microangiography
3077:
3075:
3074:
3069:
3058:
3001:
2999:
2998:
2993:
2982:
2928:
2926:
2925:
2920:
2888:
2786:
2784:
2783:
2778:
2761:
2686:
2684:
2683:
2678:
2636:
2634:
2633:
2628:
2626:
2618:
2556:
2554:
2553:
2548:
2544:
2543:
2540:
2529:
2523:
2522:
2484:
2482:
2481:
2476:
2473:
2472:
2432:
2430:
2429:
2424:
2420:
2419:
2413:
2405:
2399:
2398:
2325:
2323:
2322:
2317:
2309:
2254:
2252:
2251:
2246:
2229:
2145:vasoconstrictors
2095:
2093:
2092:
2087:
2076:
2071:
2070:
2069:
2057:
2056:
2046:
2003:
2001:
2000:
1995:
1993:
1991:
1987:
1986:
1967:
1947:
1885:
1883:
1882:
1877:
1875:
1873:
1872:
1871:
1858:
1844:
1753:
1749:
1746:
1744:
1743:
1738:
1736:
1734:
1733:
1715:
1714:
1713:
1680:
1679:
1651:
1560:
1558:
1557:
1552:
1550:
1545:
1534:
1471:
1469:
1468:
1463:
1422:
1420:
1419:
1414:
1412:
1411:
1402:
1401:
1389:
1388:
1379:
1378:
1369:
1246:
1244:
1243:
1238:
1236:
1229:
1228:
1161:For example, if
1129:of 0.40, if the
1072:
1070:
1069:
1064:
1062:
1061:
1060:
1047:
1046:
1045:
1029:
1028:
1027:
998:
996:
995:
990:
988:
987:
986:
970:
969:
968:
952:
951:
950:
935:
885:
883:
882:
877:
875:
873:
872:
863:
862:
861:
845:
840:
839:
813:
811:
810:
805:
800:
799:
787:
786:
715:
713:
712:
707:
705:
700:
699:
698:
685:
633:
631:
630:
625:
623:
621:
620:
611:
610:
601:
581:
580:
566:
552:
550:
549:
544:
536:
535:
523:
522:
501:
500:
488:
487:
461:
444:osmotic pressure
344:
342:
341:
336:
334:
333:
320:
315:
311:
310:
309:
297:
296:
282:
280:
272:
267:
266:
210:osmotic pressure
202:
200:
104:osmotic pressure
21:
6189:
6188:
6184:
6183:
6182:
6180:
6179:
6178:
6144:Fluid mechanics
6134:
6133:
6132:
6123:
6041:
5991:
5953:
5950:Vascular system
5940:
5924:
5861:
5763:
5748:(Contractility)
5707:
5659:
5650:Wiggers diagram
5563:
5558:
5528:
5523:
5465:
5459:Small intestine
5454:Large intestine
5427:
5418:
5388:
5383:
5342:Immunopathology
5322:Hematopathology
5303:
5228:
4999:
4994:
4964:
4963:
4962:
4952:
4951:
4947:
4933:
4899:2002;15:167-184
4878:
4873:
4849:
4848:
4844:
4838:
4834:
4829:
4825:
4816:
4814:
4806:
4805:
4801:
4769:
4762:
4755:
4741:
4737:
4729:
4727:
4709:
4705:
4696:
4694:
4685:
4684:
4680:
4673:
4659:
4652:
4645:
4631:
4627:
4596:
4592:
4561:
4557:
4549:
4547:
4545:
4527:
4523:
4515:
4513:
4495:
4488:
4451:
4447:
4440:
4426:
4417:
4410:
4396:
4392:
4347:
4343:
4338:
4331:
4324:
4310:
4306:
4294:
4292:
4283:
4282:
4278:
4264:
4260:
4228:
4224:
4217:
4203:
4199:
4168:
4164:
4157:
4143:
4134:
4089:
4085:
4048:
4044:
4036:
4034:
4016:
4012:
4005:
3991:
3984:
3974:
3972:
3927:
3923:
3908:
3886:
3879:
3869:
3867:
3858:
3857:
3853:
3800:
3796:
3741:
3737:
3730:
3716:
3707:
3668:
3664:
3627:
3623:
3613:
3611:
3584:
3578:
3574:
3567:
3553:
3549:
3542:
3528:
3521:
3517:
3512:
3413:combining forms
3399:
3354:
3350:
3343:
3327:
3318:
3297:
3288:
3267:
3260:
3256:
3250:
3241:
3232:
3220:
3169:
3116:
3111:
3083:brachial artery
3054:
3034:
3031:
3030:
2978:
2940:
2937:
2936:
2884:
2843:
2840:
2839:
2757:
2731:
2728:
2727:
2709:
2700:
2694:
2654:
2651:
2650:
2617:
2609:
2606:
2605:
2590:
2533:
2527:
2518:
2514:
2512:
2509:
2508:
2498:cylinder stress
2487:cylinder stress
2468:
2464:
2462:
2459:
2458:
2406:
2403:
2394:
2390:
2388:
2385:
2384:
2362:cylinder stress
2354:
2305:
2264:
2261:
2260:
2225:
2184:
2181:
2180:
2105:atherosclerotic
2065:
2061:
2052:
2048:
2047:
2045:
2043:
2040:
2039:
1982:
1978:
1968:
1948:
1946:
1938:
1935:
1934:
1867:
1863:
1859:
1845:
1843:
1832:
1829:
1828:
1815:
1809:
1804:
1784:0.03 cm/s
1720:
1716:
1688:
1684:
1657:
1653:
1652:
1650:
1639:
1636:
1635:
1597:
1535:
1533:
1522:
1519:
1518:
1505:
1496:
1436:
1433:
1432:
1407:
1403:
1397:
1393:
1384:
1380:
1374:
1370:
1365:
1345:
1342:
1341:
1330:
1314:
1265:
1260:
1227:
1219:
1216:
1215:
1209:
1202:
1194:
1187:
1180:
1173:
1166:
1156:
1149:
1143:
1139:
1134:
1127:
1120:
1113:
1105:
1098:
1088:
1081:
1056:
1052:
1051:
1041:
1037:
1033:
1023:
1019:
1012:
1010:
1007:
1006:
982:
978:
974:
964:
960:
956:
946:
942:
938:
933:
930:
929:
923:
916:
909:
894:
868:
864:
857:
853:
846:
844:
835:
831:
826:
823:
822:
795:
791:
782:
778:
749:
746:
745:
739:
732:
725:
694:
690:
686:
684:
670:
667:
666:
660:
653:
646:
616:
612:
606:
602:
600:
576:
572:
564:
561:
560:
531:
527:
518:
514:
496:
492:
483:
479:
459:
456:
455:
436:
429:
395:
387:
364:
357:
329:
325:
305:
301:
292:
288:
287:
283:
281:
271:
262:
258:
256:
253:
252:
227:Young's modulus
219:
217:Red blood cells
198:
196:
189:
172:
164:red blood cells
148:formed elements
142:is composed of
136:
130:
65:control systems
28:
23:
22:
15:
12:
11:
5:
6187:
6177:
6176:
6174:Fluid dynamics
6171:
6166:
6161:
6156:
6151:
6146:
6129:
6128:
6125:
6124:
6122:
6121:
6120:
6119:
6114:
6109:
6099:
6098:
6097:
6092:
6087:
6080:Autoregulation
6077:
6072:
6067:
6062:
6057:
6051:
6049:
6043:
6042:
6040:
6039:
6034:
6029:
6024:
6019:
6018:
6017:
6012:
6005:Pulse pressure
6001:
5999:
5997:Blood pressure
5993:
5992:
5990:
5989:
5984:
5979:
5974:
5968:
5966:
5957:
5946:
5945:
5942:
5941:
5939:
5938:
5932:
5930:
5926:
5925:
5923:
5922:
5917:
5916:
5915:
5910:
5902:
5901:
5900:
5890:
5889:
5888:
5883:
5875:
5873:Central venous
5869:
5867:
5863:
5862:
5860:
5859:
5854:
5853:
5852:
5847:
5842:
5837:
5832:
5827:
5822:
5812:
5807:
5802:
5801:
5800:
5795:
5790:
5782:
5777:
5771:
5769:
5765:
5764:
5762:
5761:
5755:
5754:(Excitability)
5749:
5743:
5733:
5723:
5717:
5715:
5709:
5708:
5706:
5705:
5700:
5695:
5690:
5685:
5679:
5669:
5667:
5661:
5660:
5658:
5657:
5652:
5647:
5642:
5637:
5632:
5627:
5622:
5621:
5620:
5615:
5605:
5604:
5603:
5598:
5591:Cardiac output
5588:
5582:
5580:
5578:Cardiac output
5571:
5565:
5564:
5557:
5556:
5549:
5542:
5534:
5525:
5524:
5522:
5521:
5516:
5515:
5514:
5509:
5504:
5499:
5491:
5490:
5489:
5484:
5475:
5473:
5467:
5466:
5464:
5463:
5462:
5461:
5456:
5451:
5446:
5437:
5435:
5429:
5428:
5417:
5416:
5409:
5402:
5394:
5385:
5384:
5382:
5381:
5376:
5371:
5366:
5364:Flow cytometry
5361:
5359:Chromatography
5356:
5351:
5345:
5344:
5339:
5334:
5329:
5324:
5319:
5313:
5311:
5305:
5304:
5302:
5301:
5296:
5291:
5286:
5281:
5279:Histopathology
5276:
5270:
5269:
5264:
5259:
5254:
5249:
5244:
5238:
5236:
5230:
5229:
5227:
5226:
5221:
5220:
5219:
5214:
5205:
5193:
5187:
5186:
5181:
5176:
5171:
5170:
5169:
5159:
5158:
5157:
5152:
5147:
5142:
5137:
5132:
5127:
5117:
5115:
5109:
5108:
5107:
5106:
5101:
5091:
5086:
5081:
5076:
5071:
5069:
5063:
5062:
5057:
5052:
5047:
5046:
5045:
5035:
5034:
5033:
5028:
5023:
5018:
5007:
5005:
5001:
5000:
4993:
4992:
4985:
4978:
4970:
4961:
4960:
4954:
4953:
4942:
4941:
4940:
4939:
4932:
4931:External links
4929:
4928:
4927:
4924:
4921:
4915:
4912:
4909:
4903:
4900:
4896:
4891:
4888:
4885:
4882:
4877:
4874:
4872:
4871:
4868:on 2020-03-22.
4851:"haemodynamic"
4842:
4832:
4823:
4799:
4774:Am. J. Cardiol
4760:
4753:
4735:
4703:
4678:
4671:
4650:
4643:
4625:
4590:
4555:
4543:
4521:
4486:
4465:(2): 340–341.
4445:
4438:
4415:
4408:
4390:
4361:(3): 553–563.
4341:
4329:
4322:
4304:
4276:
4258:
4239:(2): 188–192.
4222:
4215:
4197:
4162:
4155:
4132:
4103:(2): 230–242.
4083:
4042:
4010:
4004:978-0781739191
4003:
3982:
3941:(1): 108–113.
3921:
3906:
3877:
3851:
3814:(4): 231–236.
3794:
3735:
3728:
3705:
3684:(5): 433–438.
3662:
3639:(4): 863–888.
3621:
3572:
3565:
3547:
3540:
3518:
3516:
3513:
3511:
3510:
3505:
3500:
3495:
3490:
3485:
3480:
3475:
3470:
3465:
3463:Cardiac output
3460:
3458:Blood pressure
3455:
3449:
3445:ae/e variation
3342:
3339:
3338:
3337:
3334:
3331:
3328:
3325:
3322:
3319:
3316:
3313:
3312:Red cell mass.
3310:
3307:
3304:
3301:
3298:
3295:
3292:
3289:
3286:
3283:
3280:
3277:
3274:
3271:
3268:
3265:
3262:
3258:
3254:
3251:
3248:
3245:
3242:
3239:
3236:
3233:
3230:
3227:
3224:
3219:
3216:
3212:blood pressure
3168:
3165:
3143:blood pressure
3128:blood pressure
3115:
3112:
3110:
3107:
3079:
3078:
3067:
3064:
3061:
3057:
3053:
3050:
3047:
3044:
3041:
3038:
3024:
3023:
3016:
3013:
3010:
3003:
3002:
2991:
2988:
2985:
2981:
2977:
2974:
2971:
2968:
2965:
2962:
2959:
2956:
2953:
2950:
2947:
2944:
2930:
2929:
2918:
2915:
2912:
2909:
2906:
2903:
2900:
2897:
2894:
2891:
2887:
2883:
2880:
2877:
2874:
2871:
2868:
2865:
2862:
2859:
2856:
2853:
2850:
2847:
2801:
2800:
2797:
2794:
2776:
2773:
2770:
2767:
2764:
2760:
2756:
2753:
2750:
2747:
2744:
2741:
2738:
2735:
2708:
2707:Blood pressure
2705:
2696:Main article:
2693:
2690:
2676:
2673:
2670:
2667:
2664:
2661:
2658:
2639:
2638:
2624:
2621:
2616:
2613:
2589:
2586:
2585:
2584:
2578:
2572:
2558:
2557:
2539:
2536:
2532:
2526:
2521:
2517:
2491:
2490:
2471:
2467:
2456:
2450:
2444:
2434:
2433:
2416:
2412:
2409:
2402:
2397:
2393:
2360:Components of
2353:
2350:
2343:
2342:
2339:
2336:
2333:
2315:
2312:
2308:
2304:
2301:
2298:
2295:
2292:
2289:
2286:
2283:
2280:
2277:
2274:
2271:
2268:
2244:
2241:
2238:
2235:
2232:
2228:
2224:
2221:
2218:
2215:
2212:
2209:
2206:
2203:
2200:
2197:
2194:
2191:
2188:
2164:red blood cell
2097:
2096:
2085:
2082:
2079:
2074:
2068:
2064:
2060:
2055:
2051:
2032:
2031:
2028:
2025:
2018:
2015:
2012:
2005:
2004:
1990:
1985:
1981:
1977:
1974:
1971:
1966:
1963:
1960:
1957:
1954:
1951:
1945:
1942:
1920:
1919:
1918:
1917:
1911:
1905:
1899:
1893:
1870:
1866:
1862:
1857:
1854:
1851:
1848:
1842:
1839:
1836:
1811:Main article:
1808:
1805:
1803:
1800:
1797:
1796:
1793:
1790:
1786:
1785:
1782:
1779:
1775:
1774:
1771:
1768:
1764:
1763:
1760:
1757:
1748:
1747:
1732:
1729:
1726:
1723:
1719:
1712:
1709:
1706:
1703:
1700:
1697:
1694:
1691:
1687:
1683:
1678:
1675:
1672:
1669:
1666:
1663:
1660:
1656:
1649:
1646:
1643:
1596:
1593:
1588:
1587:
1586:
1585:
1579:
1573:
1567:
1548:
1544:
1541:
1538:
1532:
1529:
1526:
1504:
1501:
1495:
1492:
1487:
1486:
1483:
1480:
1473:
1472:
1461:
1458:
1455:
1452:
1449:
1446:
1443:
1440:
1410:
1406:
1400:
1396:
1392:
1387:
1383:
1377:
1373:
1368:
1364:
1361:
1358:
1355:
1352:
1349:
1328:
1312:
1264:
1263:Cardiac output
1261:
1259:
1256:
1248:
1247:
1234:
1226:
1223:
1207:
1200:
1192:
1185:
1178:
1171:
1164:
1154:
1147:
1141:
1137:
1132:
1125:
1118:
1112:
1109:
1103:
1096:
1086:
1079:
1074:
1073:
1059:
1055:
1050:
1044:
1040:
1036:
1032:
1026:
1022:
1018:
1015:
1000:
999:
985:
981:
977:
973:
967:
963:
959:
955:
949:
945:
941:
921:
914:
907:
892:
887:
886:
871:
867:
860:
856:
852:
849:
843:
838:
834:
830:
815:
814:
803:
798:
794:
790:
785:
781:
777:
774:
771:
768:
765:
762:
759:
756:
753:
737:
730:
723:
717:
716:
703:
697:
693:
689:
683:
680:
677:
674:
658:
651:
644:
635:
634:
619:
615:
609:
605:
599:
596:
593:
590:
587:
584:
579:
575:
571:
554:
553:
542:
539:
534:
530:
526:
521:
517:
513:
510:
507:
504:
499:
495:
491:
486:
482:
478:
475:
472:
469:
466:
434:
427:
394:
391:
385:
362:
355:
346:
345:
332:
328:
323:
318:
314:
308:
304:
300:
295:
291:
286:
278:
275:
270:
265:
261:
223:red blood cell
218:
215:
188:
185:
171:
168:
132:Main article:
129:
126:
92:carbon dioxide
57:autoregulation
55:mechanisms of
26:
9:
6:
4:
3:
2:
6186:
6175:
6172:
6170:
6167:
6165:
6162:
6160:
6157:
6155:
6152:
6150:
6147:
6145:
6142:
6141:
6139:
6118:
6115:
6113:
6110:
6108:
6105:
6104:
6103:
6100:
6096:
6093:
6091:
6088:
6086:
6083:
6082:
6081:
6078:
6076:
6073:
6071:
6068:
6066:
6063:
6061:
6058:
6056:
6053:
6052:
6050:
6048:
6044:
6038:
6035:
6033:
6030:
6028:
6025:
6023:
6020:
6016:
6013:
6011:
6008:
6007:
6006:
6003:
6002:
6000:
5998:
5994:
5988:
5985:
5983:
5980:
5978:
5975:
5973:
5970:
5969:
5967:
5965:
5961:
5958:
5956:
5951:
5947:
5937:
5934:
5933:
5931:
5927:
5921:
5918:
5914:
5911:
5909:
5906:
5905:
5903:
5899:
5896:
5895:
5894:
5891:
5887:
5884:
5882:
5879:
5878:
5876:
5874:
5871:
5870:
5868:
5864:
5858:
5855:
5851:
5848:
5846:
5843:
5841:
5838:
5836:
5833:
5831:
5828:
5826:
5823:
5821:
5818:
5817:
5816:
5813:
5811:
5808:
5806:
5803:
5799:
5796:
5794:
5791:
5789:
5786:
5785:
5783:
5781:
5778:
5776:
5773:
5772:
5770:
5766:
5759:
5756:
5753:
5750:
5747:
5744:
5741:
5737:
5734:
5731:
5727:
5724:
5722:
5719:
5718:
5716:
5714:
5710:
5704:
5701:
5699:
5698:Cardiac index
5696:
5694:
5691:
5689:
5686:
5683:
5680:
5678:
5674:
5671:
5670:
5668:
5666:
5662:
5656:
5653:
5651:
5648:
5646:
5643:
5641:
5638:
5636:
5633:
5631:
5628:
5626:
5623:
5619:
5616:
5614:
5611:
5610:
5609:
5608:Stroke volume
5606:
5602:
5601:Stroke volume
5599:
5597:
5594:
5593:
5592:
5589:
5587:
5586:Cardiac cycle
5584:
5583:
5581:
5579:
5575:
5572:
5570:
5566:
5562:
5555:
5550:
5548:
5543:
5541:
5536:
5535:
5532:
5520:
5517:
5513:
5510:
5508:
5505:
5503:
5500:
5498:
5495:
5494:
5492:
5488:
5485:
5483:
5480:
5479:
5477:
5476:
5474:
5472:
5468:
5460:
5457:
5455:
5452:
5450:
5447:
5445:
5442:
5441:
5439:
5438:
5436:
5434:
5430:
5426:
5422:
5415:
5410:
5408:
5403:
5401:
5396:
5395:
5392:
5380:
5377:
5375:
5372:
5370:
5367:
5365:
5362:
5360:
5357:
5355:
5352:
5350:
5347:
5346:
5343:
5340:
5338:
5335:
5333:
5330:
5328:
5325:
5323:
5320:
5318:
5315:
5314:
5312:
5310:
5306:
5300:
5297:
5295:
5292:
5290:
5287:
5285:
5282:
5280:
5277:
5275:
5272:
5271:
5268:
5265:
5263:
5260:
5258:
5255:
5253:
5250:
5248:
5247:Cytopathology
5245:
5243:
5240:
5239:
5237:
5235:
5231:
5225:
5222:
5218:
5215:
5213:
5209:
5206:
5204:
5201:
5200:
5199:
5198:
5194:
5192:
5191:Accumulations
5189:
5188:
5185:
5182:
5180:
5177:
5175:
5172:
5168:
5165:
5164:
5163:
5160:
5156:
5153:
5151:
5148:
5146:
5143:
5141:
5138:
5136:
5133:
5131:
5128:
5126:
5123:
5122:
5121:
5118:
5116:
5114:
5111:
5110:
5105:
5102:
5100:
5097:
5096:
5095:
5092:
5090:
5087:
5085:
5082:
5080:
5077:
5075:
5072:
5070:
5068:
5065:
5064:
5061:
5060:Wound healing
5058:
5056:
5053:
5051:
5048:
5044:
5041:
5040:
5039:
5036:
5032:
5029:
5027:
5024:
5022:
5019:
5017:
5014:
5013:
5012:
5009:
5008:
5006:
5002:
4998:
4991:
4986:
4984:
4979:
4977:
4972:
4971:
4968:
4959:
4956:
4955:
4950:
4945:
4938:
4935:
4934:
4925:
4922:
4920:
4916:
4913:
4910:
4907:
4904:
4901:
4897:
4895:
4892:
4889:
4886:
4883:
4880:
4879:
4867:
4863:
4859:
4857:
4852:
4846:
4836:
4827:
4813:
4809:
4803:
4795:
4791:
4787:
4783:
4779:
4775:
4767:
4765:
4756:
4750:
4746:
4739:
4726:
4722:
4718:
4714:
4707:
4693:on 2016-03-18
4692:
4688:
4682:
4674:
4668:
4664:
4657:
4655:
4646:
4640:
4636:
4629:
4621:
4617:
4613:
4609:
4605:
4601:
4594:
4586:
4582:
4578:
4574:
4570:
4566:
4559:
4546:
4540:
4536:
4532:
4525:
4512:
4508:
4504:
4500:
4493:
4491:
4482:
4478:
4473:
4468:
4464:
4460:
4456:
4449:
4441:
4435:
4431:
4424:
4422:
4420:
4411:
4405:
4401:
4394:
4386:
4382:
4377:
4372:
4368:
4364:
4360:
4356:
4352:
4345:
4336:
4334:
4325:
4319:
4315:
4308:
4300:
4295:|agency=
4287:
4279:
4273:
4269:
4262:
4254:
4250:
4246:
4242:
4238:
4234:
4226:
4218:
4212:
4208:
4201:
4193:
4189:
4185:
4181:
4177:
4173:
4166:
4158:
4152:
4148:
4141:
4139:
4137:
4128:
4124:
4119:
4114:
4110:
4106:
4102:
4098:
4094:
4087:
4079:
4075:
4070:
4065:
4062:: S137–S142.
4061:
4057:
4053:
4046:
4033:
4029:
4025:
4021:
4014:
4006:
4000:
3996:
3989:
3987:
3970:
3966:
3962:
3958:
3954:
3949:
3944:
3940:
3936:
3932:
3925:
3917:
3913:
3909:
3903:
3899:
3895:
3891:
3884:
3882:
3865:
3861:
3855:
3847:
3843:
3838:
3833:
3829:
3825:
3821:
3817:
3813:
3809:
3805:
3798:
3790:
3786:
3781:
3776:
3772:
3768:
3763:
3758:
3754:
3750:
3746:
3739:
3731:
3725:
3721:
3714:
3712:
3710:
3701:
3697:
3692:
3687:
3683:
3679:
3678:
3673:
3666:
3659:
3654:
3650:
3646:
3642:
3638:
3634:
3633:
3625:
3610:
3606:
3602:
3598:
3594:
3590:
3583:
3576:
3568:
3562:
3558:
3551:
3543:
3537:
3533:
3526:
3524:
3519:
3509:
3506:
3504:
3501:
3499:
3496:
3494:
3491:
3489:
3486:
3484:
3481:
3479:
3476:
3474:
3471:
3469:
3466:
3464:
3461:
3459:
3456:
3454:
3451:
3450:
3448:
3446:
3442:
3438:
3434:
3430:
3429:
3424:
3420:
3419:
3414:
3408:
3348:
3335:
3332:
3329:
3323:
3320:
3314:
3311:
3308:
3305:
3302:
3299:
3293:
3290:
3284:
3281:
3278:
3275:
3272:
3269:
3263:
3252:
3246:
3243:
3237:
3234:
3228:
3225:
3222:
3221:
3215:
3213:
3209:
3205:
3201:
3197:
3193:
3189:
3185:
3177:
3173:
3164:
3162:
3157:
3154:
3152:
3148:
3144:
3140:
3133:
3129:
3125:
3120:
3106:
3104:
3100:
3095:
3091:
3088:
3084:
3065:
3062:
3059:
3055:
3051:
3048:
3045:
3042:
3039:
3036:
3029:
3028:
3027:
3021:
3017:
3014:
3011:
3008:
3007:
3006:
2989:
2986:
2983:
2979:
2972:
2969:
2966:
2963:
2960:
2957:
2954:
2948:
2945:
2942:
2935:
2934:
2933:
2916:
2913:
2910:
2907:
2904:
2901:
2898:
2895:
2892:
2889:
2885:
2881:
2878:
2875:
2872:
2869:
2866:
2863:
2860:
2857:
2854:
2851:
2848:
2845:
2838:
2837:
2836:
2833:
2831:
2827:
2823:
2819:
2815:
2811:
2807:
2798:
2795:
2792:
2791:
2790:
2787:
2771:
2768:
2762:
2758:
2754:
2751:
2748:
2745:
2742:
2739:
2736:
2733:
2725:
2723:
2719:
2715:
2704:
2699:
2674:
2671:
2668:
2665:
2662:
2659:
2656:
2647:
2643:
2622:
2619:
2614:
2611:
2604:
2603:
2602:
2600:
2596:
2582:
2579:
2576:
2573:
2570:
2566:
2563:
2562:
2561:
2537:
2534:
2530:
2524:
2519:
2515:
2507:
2506:
2505:
2503:
2499:
2494:
2488:
2469:
2465:
2457:
2454:
2451:
2448:
2445:
2442:
2439:
2438:
2437:
2414:
2410:
2407:
2400:
2395:
2391:
2383:
2382:
2381:
2379:
2375:
2371:
2363:
2358:
2349:
2346:
2340:
2337:
2334:
2331:
2330:
2329:
2326:
2313:
2310:
2306:
2299:
2296:
2293:
2290:
2287:
2284:
2281:
2275:
2272:
2269:
2266:
2258:
2255:
2242:
2239:
2236:
2233:
2230:
2226:
2219:
2216:
2213:
2210:
2207:
2204:
2201:
2198:
2189:
2186:
2178:
2175:
2173:
2172:blood thinner
2170:and related "
2169:
2165:
2161:
2156:
2154:
2153:nitroglycerin
2150:
2146:
2141:
2139:
2135:
2132: =
2131:
2125:
2123:
2113:
2109:
2106:
2102:
2083:
2077:
2072:
2066:
2062:
2058:
2053:
2049:
2038:
2037:
2036:
2029:
2026:
2023:
2019:
2016:
2013:
2010:
2009:
2008:
1983:
1979:
1975:
1972:
1961:
1955:
1952:
1949:
1943:
1940:
1933:
1932:
1931:
1928:
1925:
1915:
1912:
1909:
1906:
1903:
1900:
1897:
1894:
1891:
1887:
1886:
1868:
1864:
1860:
1855:
1852:
1849:
1846:
1840:
1837:
1827:
1826:
1825:
1823:
1818:
1814:
1802:Blood vessels
1795:15 cm/s
1794:
1791:
1788:
1787:
1783:
1780:
1777:
1776:
1773:40 cm/s
1772:
1769:
1766:
1765:
1761:
1758:
1755:
1754:
1730:
1727:
1724:
1721:
1717:
1710:
1707:
1704:
1701:
1698:
1695:
1692:
1689:
1685:
1681:
1676:
1673:
1670:
1667:
1664:
1661:
1658:
1654:
1647:
1644:
1641:
1634:
1633:
1632:
1630:
1629:cardiac cycle
1626:
1622:
1618:
1614:
1610:
1606:
1602:
1592:
1583:
1580:
1577:
1574:
1571:
1568:
1565:
1562:
1561:
1546:
1542:
1539:
1536:
1530:
1527:
1524:
1517:
1516:
1515:
1512:
1509:
1500:
1491:
1484:
1481:
1478:
1477:
1476:
1459:
1456:
1453:
1450:
1447:
1444:
1441:
1438:
1431:
1430:
1429:
1426:
1423:
1408:
1404:
1398:
1394:
1390:
1385:
1381:
1375:
1371:
1366:
1362:
1359:
1356:
1353:
1350:
1347:
1339:
1336:
1332:
1326:
1322:
1318:
1310:
1306:
1302:
1298:
1294:
1290:
1285:
1278:
1274:
1269:
1255:
1251:
1232:
1224:
1221:
1214:
1213:
1212:
1210:
1203:
1195:
1188:
1181:
1174:
1167:
1159:
1157:
1150:
1135:
1128:
1121:
1108:
1106:
1099:
1091:
1089:
1082:
1057:
1053:
1048:
1042:
1038:
1034:
1030:
1024:
1020:
1016:
1013:
1005:
1004:
1003:
983:
979:
975:
971:
965:
961:
957:
953:
947:
943:
939:
928:
927:
926:
924:
917:
910:
903:
899:
895:
869:
865:
858:
854:
850:
847:
841:
836:
832:
828:
821:
820:
819:
796:
792:
788:
783:
779:
772:
769:
766:
763:
760:
757:
754:
751:
744:
743:
742:
740:
733:
726:
701:
695:
691:
687:
681:
678:
675:
672:
665:
664:
663:
661:
654:
647:
640:
617:
613:
607:
603:
597:
594:
591:
588:
585:
582:
577:
573:
569:
559:
558:
557:
532:
528:
524:
519:
515:
508:
505:
497:
493:
489:
484:
480:
470:
467:
464:
454:
453:
452:
449:
445:
439:
437:
430:
422:
420:
414:
410:
408:
404:
400:
390:
388:
381:
377:
373:
369:
365:
358:
351:
330:
326:
321:
316:
312:
306:
302:
298:
293:
289:
284:
276:
273:
268:
263:
259:
251:
250:
249:
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243:gravitational
240:
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73:blood vessels
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37:haemodynamics
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6112:Carotid body
6075:Vasodilators
5963:
5955:hemodynamics
5954:
5760:(Relaxation)
5752:Bathmotropic
5726:Chronotropic
5349:Enzyme assay
5195:
5190:
5179:Karyorrhexis
5155:Myocytolysis
5145:Fat necrosis
5050:Inflammation
5038:Hemodynamics
5037:
5031:Pathogenesis
4949:Hemodynamics
4948:
4876:Bibliography
4866:the original
4854:
4845:
4835:
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4815:. Retrieved
4811:
4802:
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3440:
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3416:
3347:hemodynamics
3346:
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3161:hypervolemia
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3137:Hemodynamic
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2149:Vasodilators
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396:
393:Hemodilution
383:
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190:
176:blood plasma
173:
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122:hemorheology
119:
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31:Hemodynamics
30:
29:
6117:Glomus cell
6107:Aortic body
6102:Paraganglia
5913:ventricular
5886:ventricular
5835:QT interval
5830:QRS complex
5825:PR interval
5798:ventricular
5736:Dromotropic
5487:Hemorrhagic
5203:Hemosiderin
5084:Hyperplasia
5079:Hypertrophy
5055:Cell damage
4606:: 119–127.
4178:: 189–210.
3595:: 117–122.
2826:hydrostatic
2814:capillaries
2692:Capacitance
1898:: viscosity
1778:Capillaries
1770:3–5 cm
1309:right heart
1305:venae cavae
1297:capillaries
1279:vena cava,
247:Stokes' law
193:temperature
109:Blood is a
53:homeostatic
6138:Categories
6055:Baroreflex
5972:Compliance
5964:Blood flow
5840:ST segment
5768:Conduction
5758:Lusitropic
5730:Heart rate
5713:Heart rate
5665:Ultrasound
5596:Heart rate
5471:Infarction
5425:infarction
5369:Blood bank
5212:Lipofuscin
5208:Lipochrome
5184:Karyolysis
5113:Cell death
5094:Metaplasia
4840:4942-4963.
4817:2022-05-16
4730:2022-05-22
4717:StatPearls
4697:2016-02-06
4550:2022-05-22
4516:2022-05-16
4503:StatPearls
4037:2022-05-16
4024:StatPearls
3995:Physiology
3147:heart rate
3139:monitoring
3132:heart rate
2822:arterioles
1792:14 cm
1503:Turbulence
1293:arterioles
1258:Blood flow
407:homologous
96:metabolism
59:, just as
45:blood flow
18:Blood flow
6015:Diastolic
5987:Perfusion
5746:Inotropic
5625:Afterload
5493:Location
5440:Location
5421:Ischaemia
5224:Steatosis
5167:Apoptosis
5104:Glandular
5089:Dysplasia
5021:Neoplasia
5016:Infection
4997:Pathology
4297:ignored (
4286:cite book
3828:0022-1058
3771:0970-9185
3345:The word
3043:≈
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2675:σ
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2081:Δ
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1976:δ
1973:π
1962:δ
1956:η
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419:viscosity
317:μ
303:ρ
299:−
290:ρ
235:viscosity
180:viscosity
156:platelets
80:nutrients
6010:Systolic
5788:cardiac
5519:Gangrene
5433:Ischemia
5379:Serology
5174:Pyknosis
5120:Necrosis
5099:Squamous
5043:Ischemia
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4620:25865933
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3965:24131754
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3846:30581230
3789:21804707
3700:11368464
3609:14104265
3433:dynamics
3428:dynamics
3218:Glossary
2714:systolic
1617:diastole
1609:arteries
1595:Velocity
1277:Inferior
1273:Superior
911:and the
446:(OP). A
399:colloids
152:proteins
115:rheology
84:hormones
41:dynamics
39:are the
5630:Preload
5252:Autopsy
5217:Melanin
5197:pigment
5074:Atrophy
5011:Disease
4376:1365740
4253:8901447
4180:Bibcode
4118:3242868
3975:5 April
3957:7802266
3870:5 April
3837:6296452
3780:3146160
3658:10-37°C
3653:4898603
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2560:where:
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1301:venules
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239:inertia
174:Normal
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5881:atrial
5877:Right
5850:U wave
5845:T wave
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5502:Brain
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380:fluid
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134:Blood
128:Blood
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