425:
Scientists are able to identify blood proteins using Photo-affinity labeling, a means of using photo-reactive ligands as a labeling agent to identify targeted proteins.
445:
Smith, Graham S.; Walter, Gail L.; Walker, Robin M. (2013-01-01), Haschek, Wanda M.; Rousseaux, Colin G.; Wallig, Matthew A. (eds.),
466:
407:
589:"Large-scale inference of protein tissue origin in gram-positive sepsis plasma using quantitative targeted proteomics"
548:"Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry"
383:
230:
17:
411:
446:
587:
Malmström, E; Kilsgård, O; Hauri, S; Smeds, E; Herwald, H; Malmström, L; Malmström, J (January 2016).
286:
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331:
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245:
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Geyer, PE; Kulak, NA; Pichler, G; Holdt, LM; Teupser, D; Mann, M; Chuang (November 2013).
8:
419:
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efforts in the 1970s, and in more recent times this research has been performed using LC-
316:
291:
272:
70:
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672:
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128:
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Clinical
Chemistry : a laboratory perspective / Wendy Arneson, Jean Brickell.
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184:
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accounts for 55% of blood proteins, is a major contributor to maintaining the
702:
321:
266:
204:
172:
92:
86:
62:
513:
681:
630:
573:
395:
42:
489:"High Resolution Two-Dimensional Electrophoresis of Human Plasma Proteins"
532:
451:
Haschek and
Rousseaux's Handbook of Toxicologic Pathology (Third Edition)
379:
361:
356:
342:
311:
223:
78:
612:
415:
399:
211:
116:
119:
comprises 7% of blood proteins; conversion of fibrinogen to insoluble
403:
387:
132:
447:"Chapter 18 - Clinical Pathology in Non-Clinical Toxicology Testing"
99:
of plasma and assists, as a carrier, in the transport of lipids and
192:
136:
104:
391:
276:
58:
54:
50:
38:
120:
66:
45:. They serve many different functions, including transport of
140:
46:
586:
346:
108:
643:
444:
700:
486:
127:. The remainder of the plasma proteins (1%) are
81:is not a blood protein, as it is carried within
493:Proceedings of the National Academy of Sciences
150:
480:
453:, Boston: Academic Press, pp. 565–594,
107:make up 38% of blood proteins and transport
646:"Photoaffinity labeling of plasma proteins"
402:analyses of serum/plasma in the search for
539:
671:
661:
620:
563:
545:
522:
512:
373:
139:. All blood proteins are synthesized in
14:
701:
261:Examples of specific blood proteins:
255:Conversion of fibrinogen into fibrin
440:
438:
111:, hormones, and lipids assisting in
552:Molecular & Cellular Proteomics
408:two-dimensional gel electrophoresis
398:proteins is centered on performing
61:in activity and functioning of the
24:
459:10.1016/b978-0-12-415759-0.00018-2
25:
720:
487:Anderson NL, Anderson NG (1977).
435:
418:. The normal laboratory value of
187:; transport insoluble molecules
546:Adkins JN; et al. (2002).
27:Proteins present in blood serum
637:
580:
390:, as well as a way to monitor
240:Regulation of gene expression
77:. Contrary to popular belief,
65:. Other blood proteins act as
13:
1:
428:
406:. These efforts started with
394:. Current research regarding
7:
85:, rather than in the blood
33:, sometimes referred to as
10:
725:
663:10.3390/molecules181113831
565:10.1074/mcp.M200066-MCP200
151:Families of blood proteins
287:Alpha-1-acid glycoprotein
279:that has leaked from the
69:, complement components,
514:10.1073/pnas.74.12.5421
332:Complement component 4
327:Complement component 3
374:Clinical significance
345:(chylomicrons, VLDL,
307:Beta-2 microglobulin
297:alpha2-macroglobulin
183:create and maintain
656:(11): 13831–13859.
613:10.1038/ncomms10261
605:2016NatCo...710261M
505:1977PNAS...74.5421A
420:serum total protein
317:Human Serum Albumin
292:Alpha-1-fetoprotein
273:Alpha 1 antitrypsin
231:Regulatory proteins
131:, such as enzymes,
129:regulatory proteins
71:protease inhibitors
422:is around 7 g/dL.
337:C-reactive protein
499:(12): 5421–5425.
468:978-0-12-415759-0
392:clinical progress
259:
258:
123:is essential for
16:(Redirected from
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484:
478:
477:
476:
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442:
281:digestive system
246:Clotting factors
185:osmotic pressure
155:
154:
101:steroid hormones
97:oncotic pressure
75:kinin precursors
21:
724:
723:
719:
718:
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642:
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585:
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558:(12): 947–955.
544:
540:
485:
481:
473:
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469:
443:
436:
431:
388:diagnostic tool
384:electrophoresis
376:
302:Gamma globulins
203:participate in
153:
145:gamma globulins
143:except for the
113:immune function
83:red blood cells
31:Plasma proteins
28:
23:
22:
15:
12:
11:
5:
722:
712:
711:
709:Blood proteins
696:
695:
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636:
579:
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479:
467:
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386:is a valuable
375:
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125:blood clotting
35:blood proteins
26:
9:
6:
4:
3:
2:
721:
710:
707:
706:
704:
693:
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683:
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674:
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358:
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344:
341:
338:
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328:
325:
323:
322:Ceruloplasmin
320:
318:
315:
313:
310:
308:
305:
303:
300:
298:
295:
293:
290:
288:
285:
282:
278:
275:(neutralizes
274:
271:
268:
267:transthyretin
264:
263:
262:
254:
251:
249:
247:
244:
243:
239:
236:
234:
232:
229:
228:
225:
221:
218:
216:0.2–0.45 g/dl
215:
213:
210:
209:
206:
205:immune system
202:
199:
196:
194:
191:
190:
186:
182:
179:
176:
174:
171:
170:
166:
163:
160:
158:Blood protein
157:
156:
148:
146:
142:
138:
134:
130:
126:
122:
118:
114:
110:
106:
102:
98:
94:
93:Serum albumin
90:
88:
84:
80:
76:
72:
68:
64:
63:immune system
60:
56:
52:
48:
44:
40:
36:
32:
19:
18:Blood protein
653:
649:
639:
596:
592:
582:
555:
551:
541:
496:
492:
482:
472:, retrieved
450:
424:
396:blood plasma
382:proteins by
377:
343:Lipoproteins
265:Prealbumin (
260:
197:2.0–2.5 g/dl
177:3.5–5.0 g/dl
161:Normal level
91:
43:blood plasma
34:
30:
29:
378:Separating
362:Prothrombin
357:Transferrin
312:Haptoglobin
224:coagulation
79:haemoglobin
41:present in
593:Nat Commun
474:2020-11-16
429:References
416:proteomics
404:biomarkers
400:proteomics
212:Fibrinogen
133:proenzymes
117:Fibrinogen
650:Molecules
599:: 10261.
412:tandem MS
193:Globulins
167:Function
105:Globulins
703:Category
682:24217326
631:26732734
574:12543931
173:Albumins
137:hormones
59:minerals
55:vitamins
51:hormones
39:proteins
673:6270137
622:4729823
601:Bibcode
501:Bibcode
277:trypsin
67:enzymes
680:
670:
629:
619:
572:
533:271964
531:
524:431746
521:
465:
414:based
369:or MBP
252:<1%
237:<1%
222:Blood
135:, and
121:fibrin
47:lipids
37:, are
380:serum
339:(CRP)
141:liver
87:serum
678:PMID
627:PMID
570:PMID
529:PMID
463:ISBN
109:ions
57:and
668:PMC
658:doi
617:PMC
609:doi
560:doi
519:PMC
509:doi
455:doi
367:MBL
351:HDL
347:LDL
200:38%
180:55%
103:.
73:or
705::
676:.
666:.
654:18
652:.
648:.
625:.
615:.
607:.
595:.
591:.
568:.
554:.
550:.
527:.
517:.
507:.
497:74
495:.
491:.
461:,
449:,
437:^
349:,
219:7%
147:.
115:.
89:.
53:,
49:,
684:.
660::
633:.
611::
603::
597:7
576:.
562::
556:1
535:.
511::
503::
457::
353:)
283:)
269:)
164:%
20:)
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