252:
229:
3071:
3674:
827:; a considerable portion of the materials in "green blocks" is coke oven volatiles (COV). During the baking process of the green blocks as a part of commercial graphite production, most of the coal tar binders are vaporised and are generally burned in an incinerator to prevent release into the atmosphere, as COV and coal tar can be injurious to health.
953:, causes cancer, because there is insufficient data to make a judgment. While coal tar consistently causes cancer in cohorts of workers with chronic occupational exposure, animal models, and mechanistic studies, the data on short-term use as medicine in humans has so far failed to show any consistently significant increase in rates of cancer.
2249:
9.5.1 Coal tar chemicals: Coal tar is a black or dark brown liquid or a high-viscosity semi-solid that is one of the by-products formed when coal is carbonized. Coal tars are complex and variable mixtures of polycyclic aromatic hydrocarbons (PAHs), phenols, and heterocyclic compounds. Because of its
1653:
it was concluded that there is sufficient evidence in humans for the carcinogenicity of occupational exposures during paving and roofing with coal tar pitch. ... Six coal-tar pitches and three extracts of coal-tar pitches all produced skin tumours, including carcinomas, when applied to the skin of
1543:
composition of coal tar will be influenced by the process used for pyrolytic distillation as well as by the original composition of the coal ... He then demonstrated excess cancers occurring in laboratory animals when coal tar is applied to the ears and skin ... is thought to involve decreased
997:
In response to public health concerns regarding the carcinogenicity of PAHs some municipalities, such as the city of
Milwaukee, have banned the use of common coal tar-based road and driveway sealants citing concerns of elevated PAH content in groundwater.
719:) also known as liquor carbonis detergens (LCD). Named brands include Denorex, Balnetar, Psoriasin, Tegrin, T/Gel, and Neutar. When used in the extemporaneous preparation of topical medications, it is supplied in the form of coal tar topical solution
781:, however several areas have banned its use in sealcoat products, including the District of Columbia; the city of Austin, Texas; Dane County, Wisconsin; the state of Washington; and several municipalities in Minnesota and others.
964:
and cytotoxicity in epidermal cells. It's possible that the skin can repair itself from this damage after short-term exposure to PAHs but not after long-term exposure. Long-term skin exposure to these compounds can produce
22:
776:
products used to protect the structural integrity of the underlying pavement. Sealcoat products that are coal-tar based typically contain 20 to 35 percent coal-tar pitch. Research shows it is used throughout the
2501:
310:
Coal tar was discovered circa 1665 and used for medical purposes as early as the 1800s. Circa 1850, the discovery that it could be used as the main raw material for the synthesis of
2618:
Pan TL, Wang PW, Aljuffali IA, Huang CT, Lee CW, Fang JY (April 2015). "The impact of urban particulate pollution on skin barrier function and the subsequent drug absorption".
789:
In modern times, coal tar is mostly traded as fuel and an application for tar, such as roofing. The total value of the trade in coal tar is around US$ 20 billion each year.
840:. Coal tar pitch act as the binder for solid filler that can be either coke or calcined anthracite, forming electrode paste, also widely known as Söderberg electrode paste.
2653:
Qiao Y, Li Q, Du HY, Wang QW, Huang Y, Liu W (July 2017). "Airborne polycyclic aromatic hydrocarbons trigger human skin cells aging through aryl hydrocarbon receptor".
638:
1778:
2497:
2810:
3714:
2048:
1742:
1050:
765:. Today, petroleum derived binders and sealers are more commonly used. These sealers are used to extend the life and reduce maintenance cost associated with
91:
3337:
3327:
3295:
980:. Modern studies have shown that working with coal tar pitch, such as during the paving of roads or when working on roofs, increases the risk of cancer.
833:
1544:
epidermal proliferation ... Coal tar is classified as a human carcinogen ... Both inhalation and dermal routes of exposure are considered hazardous.
3719:
1699:
2077:
1876:
2250:
flammable composition, coal tar is often used for fire boilers in order to create heat. They must be heated before any heavy oil flows easily.
1637:
2759:
1588:. US: Agency for Toxic Substances Disease Registry, Division of Toxicology, Dept. of Health and Human Services, Public Health Service. 2002.
1038:
976:
Coal tar was one of the first chemical substances proven to cause cancer from occupational exposure, during research in 1775 on the cause of
304:
61:
2728:
590:
1896:
keratolytic agent that inhibits excessive proliferation of epidermal cells by reducing DNA synthesis and mitotic activity to normal levels
400:
Coal tar is a mixture of approximately 10,000 chemicals, of which only about 50% have been identified. Most of the chemical compounds are
1496:
1373:
1326:
984:
2973:
1719:...are classified as carcinogens of category 1B in accordance with Annex VI to Regulation (EC) No 1272/2008 of the European Parliament
1998:
Van Metre PC, Mahler BJ (December 2010). "Contribution of PAHs from coal-tar pavement sealcoat and other sources to 40 U.S. lakes".
3422:
994:, meaning they directly cause cancer. The U.S. Department of Health and Human Services lists coal tars as known human carcinogens.
3534:
2284:"CDC - Immediately Dangerous to Life or Health Concentrations (IDLH): Coal tar pitch volatiles - NIOSH Publications and Products"
949:. Evidence is inconclusive whether medical coal tar, which does not remain on the skin for the long periods seen in occupational
2135:
2456:
2106:
1448:
1177:
2422:
3628:
2317:
2242:
315:
2696:. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Lyon (FR): International Agency for Research on Cancer.
2470:
960:, and it is believed that their metabolites bind to DNA, damaging it. The PAHs found in coal tar and air pollution induce
2866:
3322:
2041:
1801:
1764:
2225:
Speight JG (2015). "Coal gasification processes for synthetic liquid fuel production". In Luque R, Speight JG (eds.).
3704:
2798:
2722:
2158:
1917:
1683:
1536:
1490:
1367:
1320:
1290:
1243:
1213:
3645:
988:
957:
1340:
3150:
2832:
606:
408:
401:
346:
121:
1976:
1877:"WHO Model Prescribing Information: Drugs Used in Skin Diseases: Keratoplastic and keratolytic agents: Coal tar"
1037:
Exposure to coal tar pitch volatiles can occur in the workplace by breathing, skin contact, or eye contact. The
3003:
1022:
724:
303:
preservative and used in the surfacing of roads. Coal tar was listed as a known human carcinogen in the first
2784:
1851:
1734:
926:
891:
2577:
Roelofzen JH, Aben KK, Oldenhof UT, Coenraads PJ, Alkemade HA, van de
Kerkhof PC, et al. (April 2010).
3415:
1073:
977:
247:
188:
208:
3664:
3342:
2073:
1884:
1774:
1054:
1042:
720:
1707:
1061:-extractable fraction over an 8-hour workday. At levels of 80 mg/m, coal tar pitch volatiles are
3140:
2687:
1973:"Coal-Tar-Based Pavement Sealcoat, Polycyclic Aromatic Hydrocarbons (PAHs), and Environmental Health"
1412:
1270:
1026:
877:
697:
296:
2525:"Skin disease after occupational dermal exposure to coal tar: a review of the scientific literature"
2262:
1628:
3393:
Note: Peat is considered a precursor to coal. Graphite is only technically considered a coal type.
3212:
3125:
3120:
2474:
1017:
of high-temperature coal tar, primarily a complex mixture of three or more membered condensed ring
778:
341:
is not typically recommended. The exact mechanism of action is unknown. It is a complex mixture of
224:
2748:
950:
3694:
3633:
3408:
3372:
2707:
2167:
2100:"Ordinance 80 : Establishing Regulations on Coal Tar Sealcoat Products Application and Sale"
970:
79:
41:
589:
Coal tar derivatives are contra-indicated for people with the inherited red cell blood disorder
3347:
3155:
1769:
937:, coal tar concentrations between 0.5% and 5% are considered safe and effective for psoriasis.
2343:"The use of thermomechanical analysis to characterise Söderberg electrode paste raw materials"
1607:
1480:
1357:
1310:
1203:
3202:
3100:
1069:
661:
610:
471:
350:
292:
136:
2891:
2160:
Causes of
Increasing Concentrations of Polycyclic Aromatic Hydrocarbons (PAHs) in U.S. Lakes
1910:
Clinical pharmacy : a practical approach - Society of
Hospital Pharmacists of Australia
929:, coal tar is a valuable, safe and inexpensive treatment option for millions of people with
3207:
3182:
2936:
2579:"No increased risk of cancer after coal tar treatment in patients with psoriasis or eczema"
2350:
2007:
1018:
754:
593:(G6PD deficiency), as they can cause oxidative stress leading to red blood cell breakdown.
197:
161:
8:
3285:
3145:
3045:
152:
2963:
2940:
2354:
2341:
Beukes JP, Roos H, Shoko L, Van Zyl PG, Neomagus HW, Strydom CA, Dawson NF (June 2013).
2011:
1010:, so skin treated with topical coal tar preparations should be protected from sunlight.
582:. Paracetamol may be the only coal-tar derived analgesic still in use today. Industrial
251:
228:
3709:
3357:
3300:
3270:
3260:
3217:
2996:
2554:
2403:
2234:
1815:
Jones AW (June 2011). "Early drug discovery and the rise of pharmaceutical chemistry".
1528:
1136:
1111:
911:
646:
470:
methylated and polymethylated derivatives, mono- and polyhydroxylated derivatives, and
330:
319:
280:
2386:
Ronalds BF (2019). "Bonnington
Chemical Works (1822-1878): Pioneer Coal Tar Company".
865:
coal tar to separate these out, leading to the discovery of many industrial chemicals.
3362:
3290:
3237:
3090:
2718:
2670:
2635:
2600:
2558:
2546:
2407:
2368:
2323:
2313:
2238:
2131:
2023:
1950:
1913:
1832:
1679:
1589:
1532:
1486:
1363:
1316:
1286:
1239:
1209:
1141:
1068:
When used as a medication in the United States, coal tar preparations are considered
945:
Long-term, consistent exposure to coal tar likely increases the risk of non-melanoma
673:
511:
448:
358:
2448:
2099:
2019:
1440:
1166:
3352:
3105:
2944:
2859:"CDC – NIOSH Pocket Guide to Chemical Hazards – Coal tar pitch volatiles"
2662:
2631:
2627:
2590:
2536:
2426:
2395:
2358:
2230:
2015:
1942:
1849:
1824:
1671:
1565:
1524:
1420:
1278:
1131:
1123:
961:
766:
753:
Coal tar was a component of the first sealed roads. In its original development by
650:
323:
2399:
71:
3678:
3400:
3050:
2498:"Drug Products for the Control of Dandruff, Seborrheic Dermatitis, and Psoriasis"
2363:
2342:
390:
104:
23:
Coal Tar: How
Corrupt Politics and Corporate Greed Are Killing America's Children
2689:
3639:
3232:
3160:
3135:
2666:
2283:
2196:
1946:
732:
712:
704:
456:
444:
440:
432:
2907:
2858:
2688:
IARC Working Group on the
Evaluation of Carcinogenic Risks to Humans. (2012).
3699:
3688:
3431:
2989:
2968:
2372:
2327:
1593:
1387:
1007:
919:
897:
854:
681:
642:
579:
460:
366:
338:
240:
2977:. Vol. 6 (11th ed.). Cambridge University Press. pp. 595–599.
910:
Side effects of coal tar products include skin irritation, sun sensitivity,
3529:
3518:
3435:
3377:
2749:"Report on Carcinogens, Fourteenth Edition: Coal Tars and Coal-Tar Pitches"
2674:
2639:
2604:
2550:
2027:
1954:
1836:
1417:
World Health
Organization model list of essential medicines: 21st list 2019
1145:
1127:
1014:
815:
677:
601:
The exact mechanism of action is unknown. Coal tar is a complex mixture of
547:
515:
424:
416:
362:
300:
99:
2229:. Woodhead Publishing Series in Energy. Woodhead. pp. 201–220 (212).
2171:
1933:
Paghdal KV, Schwartz RA (August 2009). "Topical tar: back to the future".
620:
agent, which reduces the growth rate of skin cells and softens the skin's
3582:
3577:
3502:
3310:
3305:
3247:
3197:
3172:
2958:
2595:
2578:
1167:"Background and Environmental Exposures to Creosote in the United States"
1058:
946:
837:
761:
was tar covered with granite chips. Later the filler used was industrial
617:
575:
567:
507:
428:
264:
29:
2908:"NIOSH Pocket Guide to Chemical Hazards – Coal Tar Pitch Volatiles"
1569:
1425:
385:. Its composition varies with the process and type of coal used –
3605:
3550:
3544:
3539:
3497:
3471:
3055:
1675:
1282:
991:
799:
758:
736:
669:
571:
503:
495:
394:
354:
284:
172:
2949:
2924:
2541:
2524:
2212:
Remediation of Former
Manufactured Gas Plants and Other Coal-Tar Sites
1972:
3610:
3587:
3524:
3479:
3382:
3367:
3315:
3265:
3255:
2833:"Candidate List of substances of very high concern for Authorisation"
2388:
International
Journal for the History of Engineering & Technology
1850:
US EPA National Center for Environmental Assessment (15 March 2009).
1583:
966:
930:
915:
811:. Like most heavy oils, it must be heated before it will flow easily.
769:
pavements, primarily in asphalt road paving, car parks and walkways.
693:
689:
563:
543:
539:
378:
334:
288:
65:
2756:
National Toxicology Program, Department of Health and Human Services
1828:
3597:
3489:
3332:
3280:
3187:
3130:
3110:
3085:
3060:
1610:. Agency for Toxic Substances and Disease Registry. September 2002.
1556:
Heinz-Gerhard F (May 1963). "The Challenge in Coal Tar Chemicals".
1090:
1085:
858:
850:
824:
773:
748:
685:
665:
535:
531:
519:
464:
452:
412:
276:
268:
3070:
735: USP; this must then be diluted in an ointment base, such as
263:
is a thick dark liquid which is a by-product of the production of
3192:
3040:
1046:
862:
846:
808:
728:
657:
621:
602:
559:
483:
479:
386:
342:
2894:. Occupational Safety & Health Administration. 22 March 2012
586:
is now usually synthesized from crude oil rather than coal tar.
3177:
3095:
2962:
583:
527:
523:
499:
491:
487:
436:
420:
279:. It has both medical and industrial uses. Medicinally it is a
2576:
1907:
3030:
2806:
2522:
2523:
Moustafa GA, Xanthopoulou E, Riza E, Linos A (August 2015).
1912:. South Yarra: Macmillan Publishers Australia. p. 114.
1523:(Third ed.). Oxford: Academic Press. pp. 993–995.
213:
3275:
3227:
3115:
3035:
3012:
2910:. Centers for Disease Control and Prevention. 11 April 2011
2105:. Dane County Office of Lakes and Watersheds. 1 July 2007.
1062:
762:
684:
properties. It may be applied topically as a treatment for
382:
272:
2170:. Environmental and Energy Study Institute. Archived from
1236:
Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition
3457:
3222:
1411:
1269:
934:
311:
1429:. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
2981:
1735:"COAL TAR - National Library of Medicine HSDB Database"
639:
World Health Organization's List of Essential Medicines
329:
Side effects include skin irritation, sun sensitivity,
316:
World Health Organization's List of Essential Medicines
21:
This article is about the substance. For the book, see
2340:
1670:(5th ed.). New York: John Wiley & Sons, Inc.
914:, and skin discoloration. It is unclear if use during
798:
In the manufacture of paints, synthetic dyes (notably
333:, and skin discoloration. It is unclear if use during
3662:
2617:
1072:
pharmaceuticals and are subject to regulation by the
1051:
National Institute for Occupational Safety and Health
933:
and other scalp or skin conditions. According to the
3338:
Health and environmental impact of the coal industry
1799:
1312:
Construction Materials: Types, Uses and Applications
845:
As a feed stock for higher-value fractions, such as
641:, the most effective and safe medicines needed in a
550:. Many of these constituents are known carcinogens.
3328:
Environmental justice and coal mining in Appalachia
2736:
Evidence for carcinogenicity to humans (sufficient)
2655:
Biochemical and Biophysical Research Communications
703:
Coal tar may be used in two forms: crude coal tar (
3430:
377:Coal tar is produced through thermal destruction (
307:from the U.S. Federal Government, issued in 1980.
2799:"Sun-Sensitive Drugs (Photosensitivity to Drugs)"
2785:"Milwaukee Common Council Bans Coal Tar Sealants"
1908:Hughes J, Donnelly R, James-Chatgilaou G (2001).
1519:Roberts L (2014). "Coal Tar". In Wexler P (ed.).
3686:
1997:
1970:
1932:
1668:Kirk-Othmer Encyclopedia of Chemical Technology
1273:(2009). Stuart MC, Kouimtzi M, Hill SR (eds.).
772:Coal tar is incorporated into some parking-lot
295:(dandruff). It may be used in combination with
160:
2925:"Parking lots create sticky pollution problem"
1935:Journal of the American Academy of Dermatology
1800:Brown T, Dronsfield A, Ellis P (1 July 2005).
1441:"Coal Tar use while Breastfeeding | Drugs.com"
1049:-soluble fraction over an 8-hour workday. The
3715:World Health Organization essential medicines
3416:
2997:
1966:
1964:
1555:
1112:"Liquor picis carbonis; a carcinogenic agent"
1039:Occupational Safety and Health Administration
2652:
1238:. Jones & Bartlett Learning. p. X.
591:glucose-6-phosphate dehydrogenase deficiency
314:engendered an entire industry. It is on the
2791:
2471:"The battle to save coal tar in California"
2312:. Amsterdam: Elsevier Science. p. 60.
1971:Mahler BJ, Van Metre PC (2 February 2011).
1901:
1802:"Pain relief: from coal tar to paracetamol"
1765:"Pain relief: from coal tar to paracetamol"
1345:. National Technical Reports Library. 1980.
985:International Agency for Research on Cancer
3423:
3409:
3004:
2990:
2922:
2690:"Chemical Agents and Related Occupations."
2227:Gasification for Synthetic Fuel Production
2074:"District Bans Coal-Tar Pavement Products"
1961:
1762:
1474:
1472:
1470:
1468:
1466:
1407:
1405:
1308:
1277:. World Health Organization. p. 308.
250:
227:
2948:
2782:
2594:
2572:
2570:
2568:
2540:
2362:
1424:
1265:
1263:
1261:
1259:
1257:
1255:
1229:
1227:
1225:
1161:
1159:
1157:
1155:
1135:
1109:
566:(pain-killer) properties. These included
196:
2583:The Journal of Investigative Dermatology
2310:Asphalt materials science and technology
2209:
1793:
1304:
1302:
1233:
1205:Gas Phase Reactions in Organic Synthesis
1063:immediately dangerous to life and health
802:/Yellow #5), and photographic materials.
3720:Drugs with unknown mechanisms of action
2504:from the original on September 18, 2015
2463:
2459:from the original on 26 September 2023.
2385:
2307:
2224:
2042:"City of Austin Ordinance 20051117-070"
1926:
1843:
1808:
1518:
1478:
1463:
1402:
1355:
645:. Coal tar is generally available as a
223:
3687:
2565:
2156:
2034:
1608:"Public Health Statement for Creosote"
1558:Industrial & Engineering Chemistry
1380:
1362:. John Wiley & Sons. p. 356.
1333:
1315:. John Wiley & Sons. p. 864.
1252:
1222:
1201:
1152:
596:
241:
3404:
3296:mining disasters in the United States
2985:
2957:
1991:
1975:. U.S. Geological Survey Fact Sheet.
1814:
1729:
1727:
1700:"EUR-Lex - 32013R1272 - EN - EUR-Lex"
1665:
1623:
1621:
1619:
1617:
1514:
1512:
1510:
1508:
1506:
1419:. Geneva: World Health Organization.
1388:"History The Early Years (1863–1881)"
1299:
1021:, was listed on 13 January 2010 as a
696:. It may be used in combination with
130:
70:
2929:Environmental Science and Technology
2529:International Journal of Dermatology
2150:
2092:
2000:The Science of the Total Environment
1781:from the original on 13 October 2017
1756:
1451:from the original on 18 January 2017
1183:from the original on 25 January 2017
918:is safe for the baby and use during
337:is safe for the baby and use during
103:
2495:
2168:PAHs Increasing in Urban U.S. Lakes
2132:"Coal Tar Free America – Bans"
894:(owners of Izal brand disinfectant)
13:
3323:Environmental issues in Appalachia
2449:"Coal Tar use while Breastfeeding"
2423:"GANSG – Coal Tar Distillers"
2235:10.1016/B978-0-85709-802-3.00009-6
2066:
1724:
1666:Betts WD (1997). "Tar and pitch".
1614:
1529:10.1016/b978-0-12-386454-3.00012-9
1503:
1342:First Annual Report on Carcinogens
1103:
14:
3731:
2923:Engelhaupt E (19 November 2008).
2884:
2734:from the original on 2016-03-15.
2620:Journal of Dermatological Science
2473:. 3 December 2001. Archived from
2420:
1008:increased sensitivity to sunlight
3672:
3069:
1643:from the original on 21 May 2016
1499:from the original on 2017-09-18.
1376:from the original on 2017-09-18.
1329:from the original on 2017-09-18.
958:polycyclic aromatic hydrocarbons
870:Some British companies included:
607:polycyclic aromatic hydrocarbons
409:polycyclic aromatic hydrocarbons
347:polycyclic aromatic hydrocarbons
2869:from the original on 2015-12-08
2851:
2825:
2813:from the original on 2013-03-17
2783:Quirmbach C (7 February 2017).
2776:
2765:from the original on 2017-02-01
2741:
2700:
2681:
2646:
2611:
2516:
2489:
2441:
2414:
2379:
2334:
2301:
2276:
2255:
2218:
2203:
2189:
2138:from the original on 2014-10-06
2124:
2112:from the original on 2011-08-24
2080:from the original on 2012-12-26
2054:from the original on 2013-05-31
2020:10.1016/j.scitotenv.2010.08.014
1979:from the original on 2013-03-28
1869:
1745:from the original on 2017-05-28
1692:
1659:
1600:
1576:
1549:
1433:
742:
731:, with an additional 5% w/v of
402:polycyclic aromatic hydrocarbon
54:liquor carbonis detergens (LCD)
2632:10.1016/j.jdermsci.2015.01.011
1485:. PMPH-USA. pp. 935–936.
1349:
1195:
1176:. September 2002. p. 19.
1110:Berenblum I (September 1948).
1023:substance of very high concern
922:is not typically recommended.
892:Newton, Chambers & Company
656:Coal tar is used in medicated
553:
372:
1:
2400:10.1080/17581206.2020.1787807
2214:. Taylor & Francis Group.
1804:. Royal Society of Chemistry.
1096:
1032:
927:National Psoriasis Foundation
823:As a binder in manufacturing
318:. Coal tar is available as a
2715:IARC MONOGRAPHS SUPPLEMENT 7
2425:. Igg.org.uk. Archived from
2364:10.1016/j.mineng.2013.04.016
2263:"Market Study: Carbon Black"
1773:. Vol. 42, no. 4.
1763:Dronsfield A (1 July 2005).
1074:Food and Drug Administration
632:
7:
2157:Mahler BJ (14 April 2011).
1079:
832:As a main component of the
784:
72:Multum Consumer Information
56:liquor picis carbonis (LPC)
10:
3736:
3535:Calcipotriol/betamethasone
3343:Health effects of coal ash
3151:power in the United States
2892:"Coal Tar Pitch Volatiles"
2667:10.1016/j.bbrc.2017.04.160
1947:10.1016/j.jaad.2008.11.024
1775:Royal Society of Chemistry
1521:Encyclopedia of Toxicology
1482:Evidence Based Dermatology
1208:. CRC Press. p. 107.
1055:recommended exposure limit
1043:permissible exposure limit
746:
717:liquor picis carbonis, LPC
711:) or a coal tar solution (
562:coal tar derivatives have
20:
3623:
3596:
3570:
3563:
3511:
3488:
3470:
3450:
3443:
3391:
3246:
3078:
3067:
3019:
2809:. 2008-08-22. p. 5.
2787:. Wisconsin Public Radio.
2197:"Coal Tar Oil | OEC"
1817:Drug Testing and Analysis
1413:World Health Organization
1359:Drug Discovery: A History
1271:World Health Organization
1027:European Chemicals Agency
978:chimney sweeps' carcinoma
969:", which can progress to
940:
905:
885:Lancashire Tar Distillers
878:Bonnington Chemical Works
698:ultraviolet light therapy
297:ultraviolet light therapy
239:
207:
187:
171:
151:
146:
120:
115:
90:
78:
60:
50:
40:
35:
3705:IARC Group 1 carcinogens
3432:Drugs used for psoriasis
3213:Greenhouse gas emissions
3011:
1275:WHO Model Formulary 2008
1001:
779:United States of America
727:solution of coal tar in
692:, and to kill and repel
459:, dibenzofluoranthenes,
3373:Problems in coal mining
2974:Encyclopædia Britannica
1852:"Hematologic Disorders"
1116:British Medical Journal
1057:(REL) of 0.1 mg/m
971:squamous cell carcinoma
956:Coal tar contains many
807:For heating or to fire
627:
299:. Industrially it is a
46:Balnetar, Cutar, others
3348:History of coal mining
1770:Education in Chemistry
1128:10.1136/bmj.2.4577.601
888:Midland Tar Distillers
723:, which consists of a
716:
708:
611:heterocyclic compounds
472:heterocyclic compounds
351:heterocyclic compounds
3203:Fossil fuel phase-out
3101:Black coal equivalent
2717:. IARC. p. 175.
2708:"COAL-TARS (Group I)"
1309:Hornbostel C (1991).
1070:over-the-counter drug
1019:aromatic hydrocarbons
1013:The residue from the
305:Report on Carcinogens
293:seborrheic dermatitis
3208:Great Smog of London
3141:pollution mitigation
2596:10.1038/jid.2009.389
2496:FDA (1 April 2015).
2347:Minerals Engineering
2210:Hathaway AW (2011).
2047:. 17 November 2005.
1777:. pp. 102–105.
882:British Tar Products
755:Edgar Purnell Hooley
139: / Rx-only
3126:fired power station
3121:combustion products
3046:Sub-bituminous coal
3023:(lowest to highest)
3020:Coal types by grade
2941:2009EnST...43....3E
2837:echa.europa.eu/home
2355:2013MiEng..46..167B
2308:Speight JG (2015).
2012:2010ScTEn.409..334V
1570:10.1021/ie50641a006
1479:Maibach HI (2011).
1234:Hamilton R (2015).
1045:) to 0.2 mg/m
1041:(OSHA) has set the
987:lists coal tars as
637:Coal tar is on the
597:Mechanism of action
512:methyl-naphthalenes
32:
3650:Never to phase III
3261:Black lung disease
3238:Toxic heavy metals
3218:Metallurgical coal
2349:. 46–47: 167–176.
1739:toxnet.nlm.nih.gov
1676:10.1002/0471238961
1356:Sneader W (2005).
1053:(NIOSH) has set a
912:allergic reactions
668:. It demonstrates
647:generic medication
538:, phenanthracene,
449:benzofluoranthenes
353:. It demonstrates
331:allergic reactions
320:generic medication
281:topical medication
275:. It is a type of
28:
3660:
3659:
3619:
3618:
3559:
3558:
3398:
3397:
3156:preparation plant
3091:Asian brown cloud
3024:
2950:10.1021/es803118b
2542:10.1111/ijd.12903
2319:978-0-12-800501-9
2244:978-0-85709-802-3
2177:on 5 October 2011
1704:eur-lex.europa.eu
1202:Vallee Y (1998).
925:According to the
898:Sadlers Chemicals
836:used in electric
674:anti-inflammatory
359:anti-inflammatory
258:
257:
209:CompTox Dashboard
134:
3727:
3677:
3676:
3675:
3668:
3568:
3567:
3448:
3447:
3425:
3418:
3411:
3402:
3401:
3353:Hydrogen sulfide
3073:
3022:
3006:
2999:
2992:
2983:
2982:
2978:
2966:
2964:"Coal-Tar"
2954:
2952:
2919:
2917:
2915:
2903:
2901:
2899:
2878:
2877:
2875:
2874:
2855:
2849:
2848:
2846:
2844:
2829:
2823:
2822:
2820:
2818:
2795:
2789:
2788:
2780:
2774:
2773:
2771:
2770:
2764:
2753:
2745:
2739:
2738:
2733:
2712:
2704:
2698:
2697:
2685:
2679:
2678:
2650:
2644:
2643:
2615:
2609:
2608:
2598:
2574:
2563:
2562:
2544:
2520:
2514:
2513:
2511:
2509:
2493:
2487:
2486:
2484:
2482:
2467:
2461:
2460:
2445:
2439:
2438:
2436:
2434:
2418:
2412:
2411:
2383:
2377:
2376:
2366:
2338:
2332:
2331:
2305:
2299:
2298:
2296:
2295:
2280:
2274:
2273:
2271:
2270:
2259:
2253:
2252:
2222:
2216:
2215:
2207:
2201:
2200:
2193:
2187:
2186:
2184:
2182:
2176:
2165:
2154:
2148:
2147:
2145:
2143:
2128:
2122:
2121:
2119:
2117:
2111:
2104:
2096:
2090:
2089:
2087:
2085:
2076:. 26 June 2009.
2070:
2064:
2063:
2061:
2059:
2053:
2046:
2038:
2032:
2031:
1995:
1989:
1988:
1986:
1984:
1968:
1959:
1958:
1930:
1924:
1923:
1905:
1899:
1898:
1893:
1892:
1883:. Archived from
1873:
1867:
1866:
1864:
1862:
1847:
1841:
1840:
1812:
1806:
1805:
1797:
1791:
1790:
1788:
1786:
1760:
1754:
1753:
1751:
1750:
1731:
1722:
1721:
1716:
1715:
1706:. Archived from
1696:
1690:
1689:
1663:
1657:
1656:
1650:
1648:
1642:
1635:
1625:
1612:
1611:
1604:
1598:
1597:
1580:
1574:
1573:
1553:
1547:
1546:
1516:
1501:
1500:
1476:
1461:
1460:
1458:
1456:
1437:
1431:
1430:
1428:
1409:
1400:
1399:
1397:
1395:
1384:
1378:
1377:
1353:
1347:
1346:
1337:
1331:
1330:
1306:
1297:
1296:
1267:
1250:
1249:
1231:
1220:
1219:
1199:
1193:
1192:
1190:
1188:
1182:
1171:
1163:
1150:
1149:
1139:
1107:
1006:Coal tar causes
962:immunosenescence
651:over the counter
324:over the counter
254:
243:
232:
231:
217:
215:
200:
164:
132:
129:
107:
74:
33:
31:
27:
18:Chemical mixture
3735:
3734:
3730:
3729:
3728:
3726:
3725:
3724:
3685:
3684:
3683:
3673:
3671:
3663:
3661:
3656:
3655:
3640:Clinical trials
3615:
3592:
3555:
3507:
3484:
3466:
3439:
3429:
3399:
3394:
3387:
3242:
3079:Coal combustion
3074:
3065:
3051:Bituminous coal
3021:
3015:
3010:
2913:
2911:
2906:
2897:
2895:
2890:
2887:
2882:
2881:
2872:
2870:
2857:
2856:
2852:
2842:
2840:
2831:
2830:
2826:
2816:
2814:
2797:
2796:
2792:
2781:
2777:
2768:
2766:
2762:
2751:
2747:
2746:
2742:
2731:
2725:
2710:
2706:
2705:
2701:
2686:
2682:
2651:
2647:
2616:
2612:
2575:
2566:
2521:
2517:
2507:
2505:
2494:
2490:
2480:
2478:
2469:
2468:
2464:
2455:. 2 June 2023.
2447:
2446:
2442:
2432:
2430:
2419:
2415:
2384:
2380:
2339:
2335:
2320:
2306:
2302:
2293:
2291:
2282:
2281:
2277:
2268:
2266:
2261:
2260:
2256:
2245:
2223:
2219:
2208:
2204:
2195:
2194:
2190:
2180:
2178:
2174:
2163:
2155:
2151:
2141:
2139:
2130:
2129:
2125:
2115:
2113:
2109:
2102:
2098:
2097:
2093:
2083:
2081:
2072:
2071:
2067:
2057:
2055:
2051:
2044:
2040:
2039:
2035:
1996:
1992:
1982:
1980:
1969:
1962:
1931:
1927:
1920:
1906:
1902:
1890:
1888:
1875:
1874:
1870:
1860:
1858:
1848:
1844:
1829:10.1002/dta.301
1813:
1809:
1798:
1794:
1784:
1782:
1761:
1757:
1748:
1746:
1733:
1732:
1725:
1713:
1711:
1698:
1697:
1693:
1686:
1664:
1660:
1646:
1644:
1640:
1633:
1627:
1626:
1615:
1606:
1605:
1601:
1582:
1581:
1577:
1554:
1550:
1539:
1517:
1504:
1493:
1477:
1464:
1454:
1452:
1439:
1438:
1434:
1410:
1403:
1393:
1391:
1386:
1385:
1381:
1370:
1354:
1350:
1339:
1338:
1334:
1323:
1307:
1300:
1293:
1268:
1253:
1246:
1232:
1223:
1216:
1200:
1196:
1186:
1184:
1180:
1169:
1165:
1164:
1153:
1108:
1104:
1099:
1082:
1035:
1004:
943:
908:
861:era, companies
834:electrode paste
814:As a source of
787:
751:
745:
635:
630:
599:
556:
375:
235:
211:
203:
183:
167:
142:
111:
81:
55:
26:
19:
12:
11:
5:
3733:
3723:
3722:
3717:
3712:
3707:
3702:
3697:
3695:Antipsoriatics
3682:
3681:
3658:
3657:
3654:
3653:
3652:
3651:
3648:
3637:
3631:
3625:
3624:
3621:
3620:
3617:
3616:
3614:
3613:
3608:
3602:
3600:
3594:
3593:
3591:
3590:
3585:
3580:
3574:
3572:
3565:
3561:
3560:
3557:
3556:
3554:
3553:
3548:
3542:
3537:
3532:
3521:
3515:
3513:
3509:
3508:
3506:
3505:
3500:
3494:
3492:
3486:
3485:
3483:
3482:
3476:
3474:
3468:
3467:
3465:
3464:
3454:
3452:
3445:
3441:
3440:
3428:
3427:
3420:
3413:
3405:
3396:
3395:
3392:
3389:
3388:
3386:
3385:
3380:
3375:
3370:
3365:
3360:
3358:Mining regions
3355:
3350:
3345:
3340:
3335:
3330:
3325:
3320:
3319:
3318:
3313:
3308:
3303:
3298:
3293:
3288:
3286:homogenization
3283:
3273:
3268:
3263:
3258:
3252:
3250:
3244:
3243:
3241:
3240:
3235:
3233:Sulfur dioxide
3230:
3225:
3220:
3215:
3210:
3205:
3200:
3195:
3190:
3185:
3180:
3175:
3170:
3169:
3168:
3163:
3158:
3153:
3148:
3146:power in China
3143:
3138:
3133:
3128:
3123:
3113:
3108:
3103:
3098:
3093:
3088:
3082:
3080:
3076:
3075:
3068:
3066:
3064:
3063:
3058:
3053:
3048:
3043:
3038:
3033:
3027:
3025:
3017:
3016:
3009:
3008:
3001:
2994:
2986:
2980:
2979:
2955:
2920:
2904:
2886:
2885:External links
2883:
2880:
2879:
2850:
2824:
2790:
2775:
2740:
2723:
2699:
2694:Coal-Tar Pitch
2680:
2661:(3): 445–452.
2645:
2610:
2564:
2515:
2488:
2462:
2440:
2413:
2394:(1–2): 73–91.
2378:
2333:
2318:
2300:
2275:
2254:
2243:
2217:
2202:
2188:
2149:
2123:
2091:
2065:
2033:
1990:
1960:
1941:(2): 294–302.
1925:
1918:
1900:
1868:
1842:
1807:
1792:
1755:
1723:
1691:
1684:
1658:
1630:Coal-tar pitch
1613:
1599:
1575:
1548:
1537:
1502:
1491:
1462:
1432:
1401:
1379:
1368:
1348:
1332:
1321:
1298:
1291:
1251:
1244:
1221:
1214:
1194:
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1101:
1100:
1098:
1095:
1094:
1093:
1088:
1081:
1078:
1034:
1031:
1003:
1000:
942:
939:
907:
904:
903:
902:
901:
900:
895:
889:
886:
883:
880:
872:
871:
867:
866:
842:
841:
829:
828:
820:
819:
812:
804:
803:
795:
794:
786:
783:
747:Main article:
744:
741:
733:polysorbate 80
634:
631:
629:
626:
598:
595:
555:
552:
476:
475:
468:
461:benzoperylenes
457:dibenzopyrenes
433:benzanthracene
374:
371:
256:
255:
245:
237:
236:
234:
233:
220:
218:
205:
204:
202:
201:
193:
191:
185:
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182:
181:
177:
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140:
126:
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109:
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88:
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82:administration
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68:
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57:
52:
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38:
37:
17:
9:
6:
4:
3:
2:
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3721:
3718:
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3708:
3706:
3703:
3701:
3698:
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3693:
3692:
3690:
3680:
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3669:
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3647:
3644:
3643:
3641:
3638:
3635:
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3627:
3626:
3622:
3612:
3609:
3607:
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3601:
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3469:
3463:
3459:
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3433:
3426:
3421:
3419:
3414:
3412:
3407:
3406:
3403:
3390:
3384:
3381:
3379:
3376:
3374:
3371:
3369:
3366:
3364:
3361:
3359:
3356:
3354:
3351:
3349:
3346:
3344:
3341:
3339:
3336:
3334:
3331:
3329:
3326:
3324:
3321:
3317:
3314:
3312:
3309:
3307:
3304:
3302:
3301:mining region
3299:
3297:
3294:
3292:
3289:
3287:
3284:
3282:
3279:
3278:
3277:
3274:
3272:
3269:
3267:
3264:
3262:
3259:
3257:
3254:
3253:
3251:
3249:
3245:
3239:
3236:
3234:
3231:
3229:
3226:
3224:
3221:
3219:
3216:
3214:
3211:
3209:
3206:
3204:
3201:
3199:
3196:
3194:
3191:
3189:
3186:
3184:
3181:
3179:
3176:
3174:
3171:
3167:
3164:
3162:
3159:
3157:
3154:
3152:
3149:
3147:
3144:
3142:
3139:
3137:
3134:
3132:
3129:
3127:
3124:
3122:
3119:
3118:
3117:
3114:
3112:
3109:
3107:
3104:
3102:
3099:
3097:
3094:
3092:
3089:
3087:
3084:
3083:
3081:
3077:
3072:
3062:
3059:
3057:
3054:
3052:
3049:
3047:
3044:
3042:
3039:
3037:
3034:
3032:
3029:
3028:
3026:
3018:
3014:
3007:
3002:
3000:
2995:
2993:
2988:
2987:
2984:
2976:
2975:
2970:
2965:
2960:
2956:
2951:
2946:
2942:
2938:
2934:
2930:
2926:
2921:
2909:
2905:
2893:
2889:
2888:
2868:
2864:
2860:
2854:
2838:
2834:
2828:
2812:
2808:
2804:
2800:
2794:
2786:
2779:
2761:
2757:
2750:
2744:
2737:
2730:
2726:
2724:9789283214113
2720:
2716:
2709:
2703:
2695:
2691:
2684:
2676:
2672:
2668:
2664:
2660:
2656:
2649:
2641:
2637:
2633:
2629:
2625:
2621:
2614:
2606:
2602:
2597:
2592:
2589:(4): 953–61.
2588:
2584:
2580:
2573:
2571:
2569:
2560:
2556:
2552:
2548:
2543:
2538:
2535:(8): 868–79.
2534:
2530:
2526:
2519:
2503:
2499:
2492:
2477:on 2002-10-29
2476:
2472:
2466:
2458:
2454:
2450:
2444:
2429:on 2013-06-19
2428:
2424:
2417:
2409:
2405:
2401:
2397:
2393:
2389:
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242:ECHA InfoCard
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225:DTXSID1027683
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39:
36:Clinical data
34:
24:
16:
3530:Calcipotriol
3523:
3519:Fumaric acid
3461:
3378:Refined coal
3291:liquefaction
3183:Energy value
3165:
2972:
2932:
2928:
2914:13 September
2912:. Retrieved
2896:. Retrieved
2871:. Retrieved
2862:
2853:
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2827:
2815:. Retrieved
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2767:. Retrieved
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2648:
2626:(1): 51–60.
2623:
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2506:. Retrieved
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2479:. Retrieved
2475:the original
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2452:
2443:
2431:. Retrieved
2427:the original
2416:
2391:
2387:
2381:
2346:
2336:
2309:
2303:
2292:. Retrieved
2290:. 2018-11-02
2287:
2278:
2267:. Retrieved
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2226:
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2211:
2205:
2191:
2179:. Retrieved
2172:the original
2159:
2152:
2140:. Retrieved
2126:
2114:. Retrieved
2094:
2082:. Retrieved
2068:
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2036:
2003:
1999:
1993:
1981:. Retrieved
1938:
1934:
1928:
1909:
1903:
1895:
1889:. Retrieved
1885:the original
1881:apps.who.int
1880:
1871:
1859:. Retrieved
1856:hero.epa.gov
1855:
1845:
1820:
1816:
1810:
1795:
1783:. Retrieved
1768:
1758:
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1738:
1718:
1712:. Retrieved
1708:the original
1703:
1694:
1667:
1661:
1652:
1645:. Retrieved
1629:
1602:
1584:
1578:
1564:(5): 38–44.
1561:
1557:
1551:
1542:
1520:
1481:
1453:. Retrieved
1444:
1435:
1426:10665/325771
1416:
1392:. Retrieved
1382:
1358:
1351:
1341:
1335:
1311:
1274:
1235:
1204:
1197:
1185:. Retrieved
1173:
1119:
1115:
1105:
1067:
1036:
1015:distillation
1012:
1005:
996:
982:
975:
955:
947:skin cancers
944:
924:
909:
838:arc furnaces
816:carbon black
788:
771:
752:
743:Construction
709:pix carbonis
702:
655:
636:
615:
609:(PAHs), and
600:
588:
557:
548:fluoranthene
516:acenaphthene
477:
425:triphenylene
417:fluoranthene
399:
376:
369:properties.
349:(PAHs), and
328:
309:
301:railroad tie
260:
259:
122:Legal status
116:Legal status
15:
3636:from market
3583:Methoxsalen
3578:Trioxysalen
3503:Methoxsalen
3498:Trioxysalen
3248:Coal mining
3198:Fossil fuel
2803:MedicineNet
2508:26 February
2288:www.cdc.gov
1283:10665/44053
1059:cyclohexane
992:carcinogens
618:keratolytic
576:paracetamol
568:acetanilide
554:Derivatives
508:naphthalene
463:, 7-rings:
455:, 6-rings:
445:benzopyrene
441:benzopyrene
435:, 5-rings:
429:naphthacene
373:Composition
283:applied to
248:100.029.417
147:Identifiers
51:Other names
42:Trade names
3689:Categories
3606:Etretinate
3551:Tazarotene
3545:Tacalcitol
3540:Calcitriol
3271:Coalfields
3056:Anthracite
2969:Chisholm H
2873:2015-11-27
2843:27 October
2769:2017-06-10
2294:2021-10-05
2269:2013-04-26
2265:. Ceresana
1891:2017-06-10
1749:2017-06-10
1714:2017-06-10
1455:13 January
1394:4 February
1390:. Bayer AG
1187:13 January
1097:References
1033:Regulation
857:. In the
800:tartrazine
793:As a fuel.
737:petrolatum
670:antifungal
572:phenacetin
544:quinolines
504:benzofuran
411:(4-rings:
395:anthracite
391:bituminous
355:antifungal
198:R533ESO2EC
173:ChemSpider
153:CAS Number
3710:Materials
3646:Phase III
3634:Withdrawn
3611:Acitretin
3598:Retinoids
3588:Bergapten
3571:Psoralens
3525:vitamin D
3490:Psoralens
3480:Dithranol
3472:Antracens
3383:Whitedamp
3368:Peak coal
3363:Outbursts
3266:Coal dust
3256:Blackdamp
3161:seam fire
3136:phase-out
2559:205189697
2453:Drugs.com
2421:Smith M.
2408:221115202
2373:0892-6875
2328:922698102
1594:816079578
967:tar warts
931:psoriasis
916:pregnancy
863:distilled
694:head lice
690:psoriasis
678:anti-itch
633:Medicinal
564:analgesic
540:carbazole
536:picolines
496:coumarone
379:pyrolysis
363:anti-itch
335:pregnancy
289:psoriasis
287:to treat
162:8007-45-2
80:Routes of
66:Drugs.com
3679:Medicine
3564:Systemic
3462:Coal tar
3333:Firedamp
3188:Flue gas
3111:Charcoal
3086:Ash pond
3061:Graphite
2961:(1911).
2935:(1): 3.
2867:Archived
2811:Archived
2760:Archived
2729:Archived
2675:28526404
2640:25680853
2605:20016499
2551:26183242
2502:Archived
2457:Archived
2136:Archived
2107:Archived
2078:Archived
2049:Archived
2028:21112613
1977:Archived
1955:19185953
1861:21 April
1837:21698778
1779:Archived
1743:Archived
1638:Archived
1636:. IARC.
1585:Creosote
1497:Archived
1449:Archived
1415:(2019).
1374:Archived
1327:Archived
1178:Archived
1146:18882998
1091:Wood tar
1086:Coal oil
1080:See also
951:exposure
859:coal gas
851:creosote
825:graphite
785:Industry
774:sealcoat
749:Sealcoat
686:dandruff
666:ointment
616:It is a
560:phenolic
558:Various
532:pyridine
520:fluorene
478:Others:
465:coronene
453:perylene
413:chrysene
277:creosote
269:coal gas
261:Coal tar
92:ATC code
30:Coal tar
3444:Topical
3193:Fly ash
3041:Lignite
2971:(ed.).
2959:Lunge G
2937:Bibcode
2898:8 March
2863:cdc.gov
2817:8 March
2481:8 March
2433:8 March
2351:Bibcode
2181:8 March
2142:8 March
2116:8 March
2084:8 March
2058:8 March
2008:Bibcode
1983:8 March
1785:14 June
1647:10 June
1174:cdc.gov
1137:2091540
1076:(FDA).
1047:benzene
1025:by the
989:Group 1
847:naphtha
809:boilers
767:asphalt
729:alcohol
725:20% w/v
658:shampoo
622:keratin
603:phenols
528:cresols
492:cumenes
488:xylenes
484:toluene
480:benzene
387:lignite
343:phenols
108:)
102: (
86:Topical
3665:Portal
3629:WHO-EM
3311:slurry
3306:refuse
3178:Coking
3096:Asthma
2721:
2673:
2638:
2603:
2557:
2549:
2406:
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1212:
1144:
1134:
941:Cancer
906:Safety
759:tarmac
680:, and
584:phenol
574:, and
524:phenol
500:indene
437:picene
421:pyrene
365:, and
135:
3512:Other
3031:Xylit
2967:. In
2807:WebMD
2763:(PDF)
2752:(PDF)
2732:(PDF)
2711:(PDF)
2555:S2CID
2404:S2CID
2175:(PDF)
2164:(PDF)
2110:(PDF)
2103:(PDF)
2052:(PDF)
2045:(PDF)
1641:(PDF)
1634:(PDF)
1181:(PDF)
1170:(PDF)
1002:Other
855:pitch
713:Latin
705:Latin
381:) of
271:from
100:D05AA
3700:Coal
3451:Tars
3316:town
3276:Coal
3228:Smog
3173:Coke
3116:Coal
3106:Char
3036:Peat
3013:Coal
2916:2013
2900:2013
2845:2021
2839:. nd
2819:2013
2719:ISBN
2671:PMID
2636:PMID
2601:PMID
2547:PMID
2510:2016
2483:2013
2435:2013
2369:ISSN
2324:OCLC
2314:ISBN
2239:ISBN
2183:2013
2144:2013
2118:2013
2086:2013
2060:2013
2024:PMID
1985:2013
1951:PMID
1914:ISBN
1863:2020
1833:PMID
1787:2018
1680:ISBN
1654:mice
1649:2017
1590:OCLC
1533:ISBN
1487:ISBN
1457:2017
1396:2021
1364:ISBN
1317:ISBN
1287:ISBN
1240:ISBN
1210:ISBN
1189:2017
1142:PMID
983:The
853:and
763:slag
688:and
664:and
662:soap
649:and
628:Uses
578:aka
510:and
383:coal
322:and
312:dyes
291:and
285:skin
273:coal
267:and
265:coke
189:UNII
180:none
62:AHFS
3458:Tar
3436:D05
3281:gas
3223:NOx
3166:tar
3131:gas
2945:doi
2663:doi
2659:488
2628:doi
2591:doi
2587:130
2537:doi
2396:doi
2359:doi
2231:doi
2016:doi
2004:409
1943:doi
1825:doi
1672:doi
1566:doi
1525:doi
1421:hdl
1279:hdl
1132:PMC
1124:doi
935:FDA
721:USP
393:or
214:EPA
137:OTC
105:WHO
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