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been tested from March 2020. In mid-May, she announced that
Janssen's most hopeful vaccine variant will be tested on humans in July 2020. In November 2020, Jansen Vaccines announced that the production of the COVID vaccine was delayed by several months due to the occurrence of an unknown disease in one test subject in phase 3. The US regulator FDA approved the Johnson & Johnson COVID-19 vaccine for use on February 27, 2021. Approval by the European Medicines Agency was given on March 11.
237:
Early in the COVID-19 pandemic, Schuitemaker announced
Johnson & Johnson's ambition to develop a vaccine against the unknown infectious disease. Her team's approach started with the discovery of the genetic code of SARS-CoV-2, the cause of the disease COVID-19. The various vaccine candidates have
160:
in 1989. Whilst interested in the virus itself, Schuitemaker also wanted to learn more about the patients who suffered from the disease, and took part in a patient outreach program. Her interactions in this program strengthened her motivation to better understand the disease, help find a vaccine and
173:, where she was made Head of the department of Clinical Viro-Immunology in 1998. Schuitemaker has been involved in policy, and has held advisory positions on several vaccine charities. From 2003 to 2004, she was a visiting scientist at the
139:
Schuitemaker (1964) grew up in the
Netherlands. Her mother was a bookkeeper and her father was an electrical engineer. As a child she was fascinated by medicine, and after earning her undergraduate degree she completed a
720:
234:. Their approach started with a single viral genome, which was being tested as of March 2020. Schuitemaker estimated that it would take between 12 and 18 months to manufacture a vaccine.
169:
could infect other cells in the body than just T cells, including cells in the brain and lungs. She started working at
Sanquin, the Netherlands blood supply foundation based in
301:
van't Wout, A B; Kootstra, N A; Mulder-Kampinga, G A; Albrecht-van Lent, N; Scherpbier, H J; Veenstra, J; Boer, K; Coutinho, R A; Miedema, F; Schuitemaker, H (1994-11-01).
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199:. She returned to working on vaccinations to protect against HIV-1. Schuitemaker demonstrated the efficacy of the adenovirus/protein vaccines against
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Schuitemaker joined the
Academic Medical Center in Amsterdam in 2008, where she was made Chair of Experimental Immunology. She moved to
569:
303:"Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission"
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250:"Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule"
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195:. She was appointed Global Head of Viral Vaccines Discovery and Translational Medicine. At Janssen, Schuitemaker worked on the
995:
604:; Brown, Eric P.; Borducchi, Erica N.; Smith, Kaitlin M.; Nkolola, Joseph P.; Liu, Jinyan; Shields, Jennifer (2015-07-17).
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115:(since 2004). She has been involved in the development of Janssen's Ebola vaccine and is involved in the development of a
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in 2010, which, at the time, was an independent biotechnology company. Two weeks later, Crucell was acquired by
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207:. In 2018, Schuitemaker's vaccine regime was shown to induce an immune response to HIV in humans. Results of
200:
248:
Fouchier, R A; Groenink, M; Kootstra, N A; Tersmette, M; Huisman, H G; Miedema, F; Schuitemaker, H (1992).
486:
211:, an investigation into the potential for this vaccine to save the lives of thousands of young women in
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935:
570:"9 dangerous diseases that could be prevented by vaccines within the next decade, from HIV to cancer"
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is a Dutch virologist, the Global Head of Viral
Vaccine Discovery and Translational Medicine at
930:
606:"Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys"
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696:"Johnson & Johnson is about to test an experimental HIV vaccine on thousands of people"
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424:"Meet a Johnson & Johnson Researcher Poised to Crack the HIV Vaccine Code"
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780:"Vaccine scientist: 'Everything is so new in dealing with this coronavirus'"
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537:"Universal flu vaccine a step closer as scientists create experimental jabs"
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355:"Glycan recognition on HIV env by broadly neutralizing antibodies (bNAbs)"
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107:'s Janssen Vaccines & Prevention, and a Professor of Virology at the
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901:"A simple guide to the vaccines and drugs that could fight coronavirus"
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837:"FactCheck: how close are we to a vaccine or cure for coronavirus?"
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812:"Johnson & Johnson tests 10 variants of coronavirus vaccine"
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throughout her career. Her early research focussed on whether
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750:""MOSAIC" HIV Vaccine to be Tested in Thousands Globally"
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84:Role of HIV-1 monocytotropism in AIDS pathogenesis
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219:, will see 3,800 individuals taking part in a
161:treatments. She studied the pathogenesis of
884:: CS1 maint: numeric names: authors list (
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16:Dutch virologist and researcher (born 1964)
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860:Andy Extance2020-02-11T14:30:00+00:00.
487:"Women of pharma: Hanneke Schuitemaker"
215:, are expected in 2021. Another study,
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144:programme in AIDS pathogenesis at the
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671:"Un vaccino antiHIV, sogno o realtà?"
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109:Amsterdam University Medical Centers
67:Amsterdam University Medical Centers
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721:"Once feared HIV drug gets WHO nod"
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754:Biopharma from Technology Networks
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14:
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600:; Broge, Thomas; Linde, Caitlyn;
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307:Journal of Clinical Investigation
156:Schuitemaker started to research
511:"MENS #11: Hanneke Schuitemaker"
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892:
862:"The race to fight coronavirus"
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835:Lee, Georgina (17 March 2020).
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267:10.1128/jvi.66.5.3183-3187.1992
941:University of Amsterdam alumni
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986:21st-century women scientists
981:20th-century women scientists
976:21st-century Dutch scientists
971:20th-century Dutch scientists
485:Schofield, Amy (2018-03-14).
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393:Schuitemaker has three sons.
201:simian immunodeficiency virus
996:Johnson & Johnson people
899:Belluz, Julia (2020-03-04).
460:. 2017-06-25. Archived from
230:Janssen looked to develop a
7:
778:McKie, Robin (2020-03-21).
41:1964 (age 59–60)
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669:Poli, Guido (2018-07-16).
535:Sample, Ian (2015-08-24).
1006:20th-century Dutch people
966:Women medical researchers
961:Dutch medical researchers
359:Science-Business EXchange
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1001:20th-century Dutch women
135:Early life and education
630:10.1126/science.aab3886
372:10.1038/scibx.2014.1192
146:University of Amsterdam
113:University of Amsterdam
61:University of Amsterdam
946:Dutch women scientists
517:(in Dutch). 2020-01-30
454:"Hanneke Schuitemaker"
221:Phase 3 clinical trial
602:Ackerman, Margaret E.
242:Selected publications
197:universal flu vaccine
193:Johnson & Johnson
117:universal flu vaccine
105:Johnson & Johnson
1011:COVID-19 researchers
956:HIV/AIDS researchers
101:Hanneke Schuitemaker
23:Hanneke Schuitemaker
816:Nikkei Asian Review
622:2015Sci...349..320B
254:Journal of Virology
152:Research and career
365:(40): 1192. 2014.
213:Sub-Saharan Africa
1016:Ebola researchers
951:Dutch virologists
936:Women virologists
700:Los Angeles Times
616:(6245): 320–324.
320:10.1172/jci117560
228:COVID-19 pandemic
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226:During the
180:Institute.
125:RSV vaccine
121:HIV vaccine
44:Netherlands
925:Categories
910:2020-03-22
871:2020-03-22
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397:References
191:, part of
792:0029-7712
638:0036-8075
549:0261-3077
381:1945-3477
329:0021-9738
276:0022-538X
171:Amsterdam
880:cite web
656:26138104
458:ECSJ2017
209:Imbokodo
175:La Jolla
158:HIV/AIDS
64:Sanquin
647:4653134
618:Bibcode
610:Science
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217:Mosaico
185:Crucell
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