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55:. In 2000, Elston et al. proposed a "revisited", extended form of Haseman–Elston regression. Since then, further extensions to the "revisited" form of HE regression have been proposed. Although HE regression "...seems a rusty weapon in the
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278:"Comparison of Haseman–Elston regression analyses using single, summary, and longitudinal measures of systolic blood pressure"
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Haseman, J. K.; Elston, R. C. (March 1972). "The investigation of linkage between a quantitative trait and a marker locus".
429:"Estimating heritability of complex traits from genome-wide association studies using IBS-based Haseman–Elston regression"
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Wang, Tao; Elston, Robert C. (July 2005). "Two-level
Haseman–Elston regression for general pedigree data analysis".
141:"The detection of autosomal linkage in data which consist of pairs of brothers and sisters of unspecified parentage"
71:(IBS)...", HE has been adapted for association analysis in unrelated samples, whose relatedness is measured in IBS.
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in 1972. A much earlier source of sib-pair linkage implementation was, in 1935 and 1938, proposed by
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329:"Equivalence between Haseman–Elston and Variance-Components Linkage Analyses for Sib Pairs"
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Elston, Robert C.; Buxbaum, Sarah; Jacobs, Kevin B.; Olson, Jane M. (2000).
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era. This is because the HE regression relies on relatedness measured on
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10.1002/1098-2272(200007)19:1<1::AID-GEPI1>3.0.CO;2-E
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51:, who is father of Nobel laureate theoretical physicist
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Mirea, Lucia; Bull, Shelley B; Stafford, James (2003).
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223:"Haseman and Elston revisited"
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503:. You can help Knowledge by
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427:Chen, Guo-Bo (2014-04-30).
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295:10.1186/1471-2156-4-S1-S23
560:Genetic linkage analysis
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31:originally proposed for
59:analysis armory of the
180:Penrose, L.S. (1938).
139:Penrose, L.S. (1935).
29:statistical regression
433:Frontiers in Genetics
555:Statistical genetics
378:Genetic Epidemiology
227:Genetic Epidemiology
21:statistical genetics
550:Regression analysis
37:quantitative traits
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186:Annals of Eugenics
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69:identity by state
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75:References
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398:0741-0395
247:1098-2272
208:1469-1809
167:1469-1809
110:0001-8244
497:genetics
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