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History of genetics

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1897 he published a paper on his results that stated that each inherited trait was governed by two discrete particles of information, one from each parent, and that these particles were passed along intact to the next generation. In 1900 he was preparing another paper on his further results when he was shown a copy of Mendel's 1866 paper by a friend who thought it might be relevant to de Vries's work. He went ahead and published his 1900 paper without mentioning Mendel's priority. Later that same year another botanist,
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experience goes, we find it in every case confirmed that constant progeny can only be formed when the egg cells and the fertilising pollen are off like the character so that both are provided with the material for creating quite similar individuals, as is the case with the normal fertilisation of pure species. We must, therefore, regard it as certain that exactly similar factors must be at work also in the production of the constant forms in the hybrid plants."(Mendel, 1866).
794: 753: 721: 4013: 3629: 3141: 318: 708:, recognising that when some plant varieties are crossed, certain characteristics (present in one parent) usually appear in the offspring; he also found that some ancestral characteristics found in neither parent may appear in offspring. However, plant breeders made little attempt to establish a theoretical foundation for their work or to share their knowledge with current work of physiology, although 897:, who had been conducting hybridisation experiments with maize and peas, was searching the literature for related experiments prior to publishing his own results when he came across Mendel's paper, which had results similar to his own. Correns accused de Vries of appropriating terminology from Mendel's paper without crediting him or recognising his priority. At the same time another botanist, 2378: 1067:
understanding that each of the individual strands in double-stranded DNA serves as a template for new strand synthesis. In 1960, Jacob and collaborators discovered the operon which consists of a sequence of genes whose expression is coordinated by operator DNA. In the period 1961 – 1967, through work in several different labs, the nature of the genetic code was determined (e.g. ).
611: 635:. It reappeared in modern times in the 17th century and then prevailed until the 19th century. Another common term at that time was the theory of evolution, although "evolution" (in the sense of development as a pure growth process) had a completely different meaning than today. The preformists assumed that the entire organism was preformed in the 930: 892:
wondered what the nature of germ plasm might be, and in particular he wondered whether or not germ plasm was mixed like paint or whether the information was carried in discrete packets that remained unbroken. In the 1890s he was conducting breeding experiments with a variety of plant species and in
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and shows 3 generations: P1 generation (1), F1 generation (2), and F2 generation (3). Each organism inherits two alleles, one from each parent, that make up the genotype. The observed characteristic, the phenotype, is determined by the dominant allele in the genotype. In this monohybrid cross the
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of an organism was transmitted through semen (which he considered to be a purified form of blood) and the mother's menstrual blood, which interacted in the womb to direct an organism's early development. For both Hippocrates and Aristotle—and nearly all Western scholars through to the late 19th
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From his statistical analysis, Mendel defined a concept that he described as a character (which in his mind holds also for "determinant of that character"). In only one sentence of his historical paper, he used the term "factors" to designate the "material creating" the character: " So far as
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In 1947, Salvador Luria discovered the reactivation of irradiated phage leading to many further studies on the fundamental processes of repair of DNA damage (for review of early studies, see ). In 1958, Meselson and Stahl demonstrated that DNA replicates semiconservatively, leading to the
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p. 38, I:95: "This phenomenon is common in genetics as well—often we find a son who does not resemble his father at all, but closely resembles his grandfather. Undoubtedly, the genetics and resemblance were dormant within the father even though they were not outwardly apparent. Hebrew by
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was experimenting with pea breeding and producing results like Mendel's. He too discovered Mendel's paper while searching the literature for relevant work. In a subsequent paper de Vries praised Mendel and acknowledged that he had only extended his earlier work.
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as the portion of chromosomes (and perhaps other nucleoproteins) that held genes. A focus on new model organisms such as viruses and bacteria, along with the discovery of the double helical structure of DNA in 1953, marked the transition to the era of
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observed families and proposed the contribution of both males and females of hereditary characters ("sperm atoms"), noticed dominant and recessive types of inheritance and described segregation and independent assortment of "sperm atoms".
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conducted experiments involving breeding mice whose tails had been surgically removed. His results — that surgically removing a mouse's tail had no effect on the tail of its offspring — challenged the theories of pangenesis and
651:). Epigenesis had been the dominant opinion since antiquity and into the 17th century, but was then replaced by preformist ideas. Since the 19th century epigenesis was again able to establish itself as a view valid to this day. 837:, did not meet with any large degree of acceptance. A more mathematical version of pangenesis, one which dropped much of Darwin's Lamarckian holdovers, was developed as the "biometrical" school of heredity by Darwin's cousin, 736:
and traced the inheritance patterns of certain traits. Through these experiments, Mendel saw that the genotypes and phenotypes of the progeny were predictable and that some traits were dominant over others. These patterns of
408:, Hippocrates suggested that all organs of the body of a parent gave off invisible “seeds,” miniaturised components, that were transmitted during sexual intercourse and combined in the mother's womb to form a baby. In the 484:
In the following years, chemists developed techniques for sequencing both nucleic acids and proteins, while many others worked out the relationship between these two forms of biological molecules and discovered the
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that neither DNA nor protein would be required in such a primitive system as that of a very early stage of the earth if RNA could serve both as a catalyst and as genetic information storage processor.
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and Raymond Gosling produced a strikingly clear x-ray diffraction pattern indicating a helical form. Using these x-rays and information already known about the chemistry of DNA,
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and contribute to the fertilised egg and so to the next generation. The theory implied that changes to the body during an organism's life would be inherited, as proposed in
1336:, p.375: ונראה כזה בענין הטבעי, כי כמה יש מבני האדם שאינו דומה לאב כלל אך הוא דומה לאבי אביו ואין ספק כי הטבע ההוא והדמיון ההוא היה צפון באב ואף על פי שלא נראה להרגשה 1090:
discovered in 1977 that genes can be split into segments. This led to the idea that one gene can make several proteins. The successful sequencing of many organisms'
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was a supposedly well-established fact that any adequate theory of heredity had to explain. At the same time, individual species were taken to have a
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between species. Species hybridisers described a wide variety of inheritance phenomena, include hybrid sterility and the high variability of
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Min Jou W, Haegeman G, Ysebaert M, Fiers W (May 1972). "Nucleotide sequence of the gene coding for the bacteriophage MS2 coat protein".
497:. In the last decades of the 20th century, many biologists focused on large-scale genetics projects, such as sequencing entire genomes. 3876: 349: 397:
on pea plants, published in 1866, provided the initial evidence that, on its rediscovery in 1900's, helped to establish the theory of
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With the basic patterns of genetic inheritance established, many biologists turned to investigations of the physical nature of the
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https://web.archive.org/web/20120403041525/http://www.molecularstation.com/molecular-biology-images/data/503/MRNA-structure.png
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model, which was widely accepted by 1925. Alongside experimental work, mathematicians developed the statistical framework of
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https://web.archive.org/web/20120323085256/http://www.hchs.hunter.cuny.edu/index.php?title=Modern_Science&printable=yes
1141: 877:, which held that changes to an organism during its lifetime could be inherited by its descendants. Weismann proposed the 631:
The preformation theory is a developmental biological theory, which was represented in antiquity by the Greek philosopher
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Gerstein MB, Bruce C, Rozowsky JS, Zheng D, Du J, Korbel JO, Emanuelsson O, Zhang ZD, Weissman S, Snyder M (June 2007).
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Watson JD, Crick FH (25 April 1953). "Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid".
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A series of subsequent discoveries (e.g.) led to the realization decades later that the genetic material is made of
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that had been heat-killed transferred genetic information to a safe strain of the same bacteria, killing the mouse.
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In the 18th century, with increased knowledge of plant and animal diversity and the accompanying increased focus on
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Crick FH, Barnett L, Brenner S, Watts-Tobin RJ (December 1961). "General nature of the genetic code for proteins".
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demonstrated the usefulness of applying statistics to inheritance. They also contradicted 19th-century theories of
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became a central issue in the 1960s; by the 1970s gene expression could be controlled and manipulated through
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has complicated the molecular definition of the gene. In particular, genes do not always sit side by side on
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Verhandlungen des Naturforschenden Vereins zu Brünn (Proceedings of the Natural History Society of Brünn)
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theory of inheritance, which held that hereditary information was carried only in sperm and egg cells.
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of the DNA producing distinct proteins may overlap, so that the idea emerges that "genes are one long
584:(known as Albucasis in the West) was the first physician to describe clearly the hereditary nature of 3861: 3846: 3457: 3305: 2610: 335: 2600: 2542: 2458: 3866: 3685: 3599: 3479: 3474: 3414: 3387: 3226: 2900: 2408: 2404: 2388: 986: 129: 3614: 3529: 3511: 3462: 3290: 3275: 3265: 3216: 3018: 2955: 2895: 976: 942: 764:
dominant allele encodes for the colour red and the recessive allele encodes for the colour white.
581: 445: 1267: 4052: 3658: 3505: 3469: 3403: 3375: 3370: 3252: 3048: 2998: 2970: 2930: 2814: 1510: 1151: 966:. He later showed that genes occupy specific locations on the chromosome. With this knowledge, 705: 552: 524: 421: 745:, showing, rather, that genes remain discrete through multiple generations of hybridisation. 3993: 3827: 3792: 3558: 3519: 3397: 3338: 3295: 3246: 3236: 3069: 2396: 1056: 756: 738: 398: 302: 282: 247: 159: 154: 1585:
Geison, G. L. (1969). "Darwin and heredity: The evolution of his hypothesis of pangenesis".
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states characteristics are discrete and are inherited by the parents. This image depicts a
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which is transcribed by DNA. This dogma has since been shown to have exceptions, such as
1021: 1005: 1001: 898: 643:(ovism or ovulism) and only had to unfold and grow. This was contrasted by the theory of 618: 494: 458: 436: 277: 257: 192: 149: 143: 106: 2798: 2751: 2691: 2565: 2249: 2194: 2151: 2057: 1945: 1898: 1728: 1563: 1232: 34: 3932: 3817: 3812: 3787: 3584: 3452: 3421: 3221: 3211: 3116: 3064: 2925: 2910: 2890: 2864: 2773: 2650: 2526: 2323: 2271: 2214: 1964: 1929: 1837: 1812: 1747: 1712: 1688: 1663: 1188: 1118: 1103: 1083: 982: 959: 933: 818: 666: 478: 450: 272: 267: 242: 164: 2710: 2675: 2584: 2549: 2076: 2037: 2013: 1988: 1197:
Was ist 'Leben'? Aristoteles' Anschauungen zur Entstehung und Funktionsweise von Leben
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The growth of biological thought : diversity, evolution, and inheritance
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The Correlation Between Relatives on the Supposition of Mendelian Inheritance
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had been studied in a wide variety of organisms — most notably the fruit fly
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led to rapid advances in genetics. By 1915 the basic principles of Mendelian
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Geschichte der Biologie: Theorien, Methoden, Institutionen, Kurzbiographien
1252: 1071: 1017: 915: 894: 595: 568:; such inherited changes were merely superficial. The Athenian philosopher 565: 528: 486: 432: 409: 252: 2806: 2769: 2574: 2468: 2210: 2066: 2022: 1954: 1846: 1828: 1606: 849: 3897: 3574: 3081: 2719: 2517: 2101:"The operon: a group of genes with expression coordinated by an operator" 1166: 585: 536: 375: 1679: 981:
provided the first chromosomal map of any biological organism. In 1928,
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Avery, Oswald T.; MacLeod, Colin M.; McCarty, Maclyn (February 1944).
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For example, Explanatory Notes, Gartons Seed Catalogue for Spring 1901
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external links, and converting useful links where appropriate into
1114: 990: 971: 801:'s pangenesis theory. Every part of the body emits tiny particles, 648: 640: 569: 506: 440: 383: 198: 81: 71: 26: 2611:
http://www.genomenewsnetwork.org/resources/timeline/1973_Boyer.php
2294:"Genomics. DNA study forces rethink of what it means to be a gene" 1008:
showed that mutations in genes caused errors in specific steps of
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http://www.genomenewsnetwork.org/resources/timeline/1960_mRNA.php
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http://www.nature.com/physics/looking-back/crick/Crick_Watson.pdf
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http://www.accessexcellence.org/AE/AEPC/WWC/1994/geneticstln.html
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were the first to determine the sequence of a gene: the gene for
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heredity seemed to be required. Darwin's own theory of heredity,
685:) conducted extensive experiments with hybridisation, especially 2785:
Cech, T. R.; Bass, B. L. (1986). "Biological Catalysis by RNA".
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showed that genes could be transferred. In what is now known as
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After the rediscovery of Mendel's work there was a feud between
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HaLevi, Judah, translated and annotated by N. Daniel Korobkin.
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Die Logik des Lebenden. Von der Urzeugung zum genetischen Code
1193:"Function and Constraint in Aristotle and Evolutionary Theory" 1813:"A triple tribute to the experiment that transformed biology" 1772:"What is a gene, post-ENCODE? History and updated definition" 857: 806: 636: 614: 535:
The most influential early theories of heredity were that of
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Jacob F, Perrin D, Sánchez C, Monod J, Edelstein S (2005) .
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in many important plant species. In the early 19th century,
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of transmission of movements from parents to child, and of
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and his fellow "drosophilists", geneticists developed the
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inheritance of the white eyed mutation in the fruit fly
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Plant breeders were also developing an array of stable
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Olby's "Mendel, Mendelism, and Genetics," at MendelWeb
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in 1953. Together, these discoveries established the
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Cosman, Madeleine Pelner; Jones, Linda Gale (2008).
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Mendel's work was published in a relatively obscure
2726: 2622:Mutation and Expression of a Eukaryotic Protein in 2495: 732:conducted breeding experiments using the pea plant 598:described dominant and recessive genetic traits in 2676:"DNA sequencing with chain-terminating inhibitors" 1626:. Johns Hopkins University Press. pp. 116–8. 1378: 1270:. In Petermann, H.; Harper, P.; Doetz, S. (eds.). 905: 531:from the father. The model is not fully symmetric. 461:, bringing genetic explanations into the study of 2863: 2736:"Individual-specific 'fingerprints' of human DNA" 2391:may not follow Knowledge's policies or guidelines 2354:Mendel's Legacy: The Origin of Classical Genetics 1051:, which states that proteins are translated from 829:by natural selection, in which mechanisms of non- 4029: 1645: 1643: 1623:Francis Galton: Pioneer of Heredity and Biometry 1183: 1181: 1031:that DNA holds the gene's information. In 1952, 989:, injections into a mouse of a deadly strain of 1989:"Deoxyribonucleic acid repair in bacteriophage" 783: 500: 422:Aristotle's theories of genetics and embryology 1810: 1329:The Kuzari: In Defense of the Despised Faith, 3659: 3171: 3097:History of the creation-evolution controversy 2849: 2356:(Cold Spring Harbor Laboratory Press, 2004.) 2035: 1640: 1178: 343: 2464:http://www.sysbioeng.com/index/cta94-11s.jpg 2225: 1864:. New York: W.H. Freeman. pp. 299–300. 1661: 669:, new ideas about heredity began to appear. 3197:Timeline of medicine and medical technology 2231: 1884: 1710: 1302: 1296: 3666: 3652: 3178: 3164: 2856: 2842: 2474:http://cogweb.ucla.edu/ep/DNA_history.html 1199:. Franz Steiner Verlag. pp. 261–284. 350: 336: 3127:Relationship between religion and science 2759: 2709: 2699: 2649: 2583: 2573: 2550:"Chemical Structure of the Nucleic Acids" 2525: 2427:Learn how and when to remove this message 2309: 2257: 2075: 2065: 2012: 1986: 1963: 1953: 1836: 1787: 1746: 1736: 1687: 1649: 1472: 1382:; Löther, Rolf; Senglaub, Konrad (1985). 1307:. Infobase Publishing. pp. 528–529. 1265: 918:over the hereditary mechanism, solved by 547:) was similar to Darwin's later ideas on 427:The 1900 rediscovery of Mendel's work by 3361:Cardiology (invasive and interventional) 2784: 2174: 1862:Genetics A Conceptual Approach (7th ed.) 1811:Steinman RM, Moberg CL (February 1994). 1763: 1578: 1450:Genetics A Conceptual Approach (7th ed.) 1106:". It was first hypothesised in 1986 by 1043:demonstrated the molecular structure of 928: 884: 848: 792: 751: 719: 609: 519: 3999:List of genetics research organizations 3185: 2469:http://www.esp.org/books/sturt/history/ 2288: 2282: 864:in each generation from the germ plasm. 768:Mendel's work was published in 1866 as 4030: 2815:"A sheep cloning how-to, more or less" 2615: 2445: 1859: 1619: 1584: 1542: 1508: 1447: 1305:Handbook to life in the medieval world 605: 3647: 3159: 2837: 1927: 1711:Beadle GW, Tatum EL (November 1941). 1345: 1187: 962:showed that genes reside on specific 2547: 2371: 1817:The Journal of Experimental Medicine 1426: 1414: 1227: 1142:List of sequenced eukaryotic genomes 4048:History of biology by subdiscipline 2799:10.1146/annurev.bi.55.070186.003123 1386:(2nd ed.). Jena: VEB Fischer. 1237:. Belknap Press. pp. 635–640. 770:"Versuche über Pflanzen-Hybriden" ( 712:in England explained their system. 710:Gartons Agricultural Plant Breeders 655:Plant systematics and hybridisation 515: 511:Timeline of the history of genetics 13: 3004:Central dogma of molecular biology 2337: 2036:Meselson M, Stahl FW (July 1958). 1049:central dogma of molecular biology 772:Experiments on Plant Hybridisation 562:inheritance of acquired characters 14: 4069: 2367: 1509:Alfred, Randy (8 February 2010). 617:as preformed humans. Painting of 4058:History of science by discipline 4012: 4011: 3628: 3627: 3314: 3140: 3139: 2616:Struhl, Kevin (1 October 2008). 2376: 1662:Hershey AD, Chase M (May 1952). 1452:. W.H. Freeman. pp. 49–56. 1117:at the level of DNA is known as 317: 316: 203: 202: 33: 3580:List of epidemics and pandemics 2131: 2092: 2029: 1980: 1921: 1878: 1853: 1804: 1704: 1655: 1613: 1536: 1502: 1466: 1441: 1432: 1157:History of evolutionary thought 906:Emergence of molecular genetics 555:instead that the (nonphysical) 3499:History of methods in medicine 3029:One gene–one enzyme hypothesis 1420: 1408: 1372: 1350:. Frankfurt am Main: Fischer. 1339: 1321: 1259: 1221: 1162:One gene-one enzyme hypothesis 1098:like discrete beads. Instead, 970:, a member of Morgan's famous 860:. Somatic cells (of the body) 1: 3436:Medicine in ancient societies 2787:Annual Review of Biochemistry 2311:10.1126/science.316.5831.1556 1478:The Gene: An intimate history 1172: 1130:modern evolutionary synthesis 844: 788: 3958:Missing heritability problem 3673: 2680:Proc. Natl. Acad. Sci. U.S.A 2554:Proc. Natl. Acad. Sci. U.S.A 1860:Pierce, Benjamin A. (2020). 1448:Pierce, Benjamin A. (2020). 1274:. Springer. pp. 41–57. 1147:History of molecular biology 784:Post-Mendel, pre-rediscovery 661:History of plant systematics 501:Pre-Mendel ideas on heredity 7: 3205:Histories of basic sciences 2454:. Arizona State University. 2452:Embryo Project Encyclopedia 2234:"Genetics: what is a gene?" 2038:"The replication of DNA in 1928:Luria SE (September 1947). 1280:10.1007/978-3-319-51783-4_3 1135: 704:established the concept of 10: 4074: 2642:10.1534/genetics.104.96693 2341: 2117:10.1016/j.crvi.2005.04.005 2005:10.1128/mr.45.1.72-98.1981 1987:Bernstein C (March 1981). 1195:. In Föllinger, S. (ed.). 679:Carl Friedrich von Gärtner 658: 624: 504: 4007: 3986: 3885: 3836: 3780: 3719: 3681: 3623: 3567: 3498: 3435: 3323: 3312: 3204: 3193: 3135: 3057: 2989: 2876: 2480:"The history of genetics" 1272:History of Human Genetics 715: 675:Joseph Gottlieb Kölreuter 639:(animalkulism) or in the 3410:Psychiatric institutions 2344:Bibliography of genetics 2232:Pearson, H. (May 2006). 2046:Proc Natl Acad Sci U S A 1934:Proc Natl Acad Sci U S A 1717:Proc Natl Acad Sci U S A 1599:10.1093/jhmas/XXIV.4.375 1346:Jacob, François (1972). 3490:Medieval Western Europe 3463:Egyptian medical papyri 3427:Trauma and orthopaedics 2701:10.1073/pnas.74.12.5463 977:Drosophila melanogaster 805:, which migrate to the 728:Between 1856 and 1865, 673:and others (among them 582:Abu al-Qasim al-Zahrawi 446:Drosophila melanogaster 3049:Spontaneous generation 2999:Germ theory of disease 2976:Zoology (through 1859) 2827:"Human Genome Project" 1738:10.1073/pnas.27.11.499 1620:Bulmer, M. G. (2003). 1266:Yapijakis, C. (2017). 1152:History of RNA Biology 955: 946:in 1910, implying the 865: 814: 765: 725: 622: 532: 370:with contributions by 3994:List of genetic codes 3568:Disasters and plagues 3070:Philosophy of biology 2575:10.1073/pnas.40.8.748 2067:10.1073/pnas.44.7.671 1955:10.1073/pnas.33.9.253 1829:10.1084/jem.179.2.379 1587:J Hist Med Allied Sci 1476:(2016). "Chapter 4". 1057:reverse transcription 987:Griffith's experiment 932: 885:Rediscovery of Mendel 852: 796: 757:Mendelian inheritance 755: 739:Mendelian inheritance 723: 613: 557:form-giving principle 523: 399:Mendelian inheritance 303:Personalized medicine 297:Personalized medicine 160:Quantitative genetics 155:Mendelian inheritance 3893:Behavioural genetics 3334:Alternative medicine 3102:Human Genome Project 3014:Great chain of being 2981:Zoology (since 1859) 2916:Evolutionary thought 2886:Agricultural science 2518:10.1084/jem.79.2.137 2397:improve this article 1474:Mukherjee, Siddartha 1113:The modern study of 1074:and his team at the 1014:one gene, one enzyme 743:blending inheritance 724:Blending Inheritance 489:. The regulation of 418:On Animal Generation 391:Gregor Johann Mendel 223:Branches of genetics 4038:History of genetics 3973:Population genomics 3963:Molecular evolution 3923:Genetic engineering 3540:Tracheal intubation 3326:medical specialties 3187:History of medicine 3107:Humboldtian science 3044:Sequence hypothesis 2951:Molecular evolution 2752:1985Natur.316...76J 2692:1977PNAS...74.5463S 2566:1954PNAS...40..748T 2446:Andrei, A. (2013). 2409:footnote references 2250:2006Natur.441..398P 2195:1972Natur.237...82J 2152:1961Natur.192.1227C 2058:1958PNAS...44..671M 1946:1947PNAS...33..253L 1899:1953Natur.171..737W 1729:1941PNAS...27..499B 1680:10.1085/jgp.36.1.39 1564:1871Natur...3..502D 1189:Leroi, Armand Marie 1076:University of Ghent 1022:Colin Munro MacLeod 1006:Edward Lawrie Tatum 1002:George Wells Beadle 899:Erich von Tschermak 619:Nicolaas Hartsoeker 606:Preformation theory 553:Aristotle suggested 495:genetic engineering 459:population genetics 437:Erich von Tschermak 364:history of genetics 193:Genetic engineering 150:Population genetics 21:Part of a series on 3933:Genetic monitoring 3376:Emergency medicine 3117:Natural philosophy 3065:History of science 2865:History of biology 1789:10.1101/gr.6339607 1429:, pp. 649–651 1119:molecular genetics 1084:Richard J. Roberts 1010:metabolic pathways 983:Frederick Griffith 960:Thomas Hunt Morgan 956: 934:Thomas Hunt Morgan 866: 819:scientific journal 815: 766: 726: 623: 533: 479:molecular genetics 451:Thomas Hunt Morgan 165:Molecular genetics 124:History and topics 4025: 4024: 3948:He Jiankui affair 3938:Genetic genealogy 3928:Genetic diversity 3857:the British Isles 3762:Genetic variation 3641: 3640: 3535:Radiation therapy 3520:Blood transfusion 3366:Dental treatments 3271:Molecular biology 3261:Medical diagnosis 3153: 3152: 3019:Hierarchy of life 2966:Plant systematics 2946:Molecular biology 2674:(December 1977). 2548:Todd, AR (1954). 2437: 2436: 2429: 2350:Elof Axel Carlson 2244:(7092): 398–401. 2160:10.1038/1921227a0 2146:(4809): 1227–32. 1871:978-1-319-29714-5 1633:978-0-801-88140-4 1546:(27 April 1871). 1487:978-1-4767-3353-1 1459:978-1-319-29714-5 1314:978-0-8160-4887-8 1289:978-3-319-51783-4 1206:978-3-515-09244-9 1080:bacteriophage MS2 1033:Rosalind Franklin 968:Alfred Sturtevant 525:Aristotle's model 388:Augustinian friar 360: 359: 87:Genetic variation 4065: 4015: 4014: 3978:Reverse genetics 3953:Medical genetics 3668: 3661: 3654: 3645: 3644: 3631: 3630: 3318: 3180: 3173: 3166: 3157: 3156: 3143: 3142: 3122:Natural theology 2858: 2851: 2844: 2835: 2834: 2830: 2822: 2821:. February 1997. 2810: 2781: 2763: 2761:10.1038/316076a0 2723: 2713: 2703: 2663: 2653: 2624:Escherichia coli 2597: 2587: 2577: 2539: 2529: 2487: 2455: 2432: 2425: 2421: 2418: 2412: 2380: 2379: 2372: 2332: 2331: 2313: 2304:(5831): 1556–7. 2286: 2280: 2279: 2261: 2229: 2223: 2222: 2203:10.1038/237082a0 2178: 2172: 2171: 2135: 2129: 2128: 2096: 2090: 2089: 2079: 2069: 2040:Escherichia Coli 2033: 2027: 2026: 2016: 1984: 1978: 1977: 1967: 1957: 1925: 1919: 1918: 1907:10.1038/171737a0 1882: 1876: 1875: 1857: 1851: 1850: 1840: 1808: 1802: 1801: 1791: 1767: 1761: 1760: 1750: 1740: 1708: 1702: 1701: 1691: 1659: 1653: 1647: 1638: 1637: 1617: 1611: 1610: 1582: 1576: 1575: 1572:10.1038/003502a0 1540: 1534: 1533: 1531: 1529: 1506: 1500: 1499: 1470: 1464: 1463: 1445: 1439: 1436: 1430: 1424: 1418: 1417:, pp. 640–9 1412: 1406: 1405: 1376: 1370: 1369: 1343: 1337: 1325: 1319: 1318: 1300: 1294: 1293: 1263: 1257: 1256: 1225: 1219: 1218: 1185: 1128:is known as the 761:monohybrid cross 702:Augustin Sageret 576:In 1000 CE, the 516:Ancient theories 352: 345: 338: 325: 320: 319: 215:Medical genetics 211: 206: 205: 37: 18: 17: 4073: 4072: 4068: 4067: 4066: 4064: 4063: 4062: 4028: 4027: 4026: 4021: 4003: 3982: 3881: 3872:the Middle East 3838:Archaeogenetics 3832: 3776: 3715: 3677: 3672: 3642: 3637: 3619: 3563: 3494: 3431: 3319: 3310: 3200: 3189: 3184: 3154: 3149: 3131: 3112:Natural history 3053: 2991: 2985: 2941:Model organisms 2878: 2872: 2862: 2825: 2813: 2746:(6023): 76–79. 2478: 2433: 2422: 2416: 2413: 2394: 2385:This section's 2381: 2377: 2370: 2346: 2340: 2338:Further reading 2335: 2287: 2283: 2259:10.1038/441398a 2230: 2226: 2179: 2175: 2136: 2132: 2097: 2093: 2034: 2030: 1985: 1981: 1926: 1922: 1893:(4356): 737–8. 1883: 1879: 1872: 1858: 1854: 1809: 1805: 1776:Genome Research 1768: 1764: 1723:(11): 499–506. 1709: 1705: 1660: 1656: 1648: 1641: 1634: 1618: 1614: 1583: 1579: 1541: 1537: 1527: 1525: 1507: 1503: 1488: 1471: 1467: 1460: 1446: 1442: 1437: 1433: 1425: 1421: 1413: 1409: 1394: 1377: 1373: 1358: 1344: 1340: 1326: 1322: 1315: 1301: 1297: 1290: 1264: 1260: 1245: 1226: 1222: 1207: 1186: 1179: 1175: 1138: 1037:James D. Watson 912:William Bateson 908: 887: 870:August Weismann 854:August Weismann 847: 791: 786: 718: 663: 657: 629: 627:Preformationism 608: 518: 513: 503: 491:gene expression 366:dates from the 356: 315: 308: 307: 298: 290: 289: 288: 287: 236: 228: 227: 219: 197: 178: 170: 169: 125: 117: 116: 103: 102: 101: 45: 12: 11: 5: 4071: 4061: 4060: 4055: 4050: 4045: 4040: 4023: 4022: 4020: 4019: 4008: 4005: 4004: 4002: 4001: 3996: 3990: 3988: 3984: 3983: 3981: 3980: 3975: 3970: 3968:Plant genetics 3965: 3960: 3955: 3950: 3945: 3940: 3935: 3930: 3925: 3920: 3915: 3910: 3908:Genome editing 3905: 3900: 3895: 3889: 3887: 3886:Related topics 3883: 3882: 3880: 3879: 3874: 3869: 3864: 3859: 3854: 3849: 3843: 3841: 3834: 3833: 3831: 3830: 3825: 3820: 3815: 3810: 3808:Immunogenetics 3805: 3800: 3795: 3790: 3784: 3782: 3778: 3777: 3775: 3774: 3769: 3764: 3759: 3754: 3749: 3744: 3739: 3734: 3729: 3723: 3721: 3720:Key components 3717: 3716: 3714: 3713: 3708: 3703: 3698: 3693: 3688: 3682: 3679: 3678: 3671: 3670: 3663: 3656: 3648: 3639: 3638: 3636: 3635: 3624: 3621: 3620: 3618: 3617: 3612: 3607: 3602: 3597: 3592: 3587: 3582: 3577: 3571: 3569: 3565: 3564: 3562: 3561: 3556: 3555: 3554: 3542: 3537: 3532: 3527: 3522: 3517: 3516: 3515: 3502: 3500: 3496: 3495: 3493: 3492: 3487: 3485:Medieval Islam 3482: 3477: 3472: 3470:Ancient Greece 3467: 3466: 3465: 3455: 3450: 3445: 3439: 3437: 3433: 3432: 3430: 3429: 3424: 3419: 3418: 3417: 3412: 3407: 3395: 3390: 3385: 3384: 3383: 3373: 3368: 3363: 3358: 3353: 3352: 3351: 3346: 3336: 3330: 3328: 3321: 3320: 3313: 3311: 3309: 3308: 3303: 3298: 3293: 3288: 3283: 3278: 3273: 3268: 3263: 3258: 3257: 3256: 3244: 3239: 3234: 3229: 3224: 3219: 3214: 3208: 3206: 3202: 3201: 3194: 3191: 3190: 3183: 3182: 3175: 3168: 3160: 3151: 3150: 3148: 3147: 3136: 3133: 3132: 3130: 3129: 3124: 3119: 3114: 3109: 3104: 3099: 3094: 3089: 3084: 3079: 3078: 3077: 3067: 3061: 3059: 3055: 3054: 3052: 3051: 3046: 3041: 3036: 3031: 3026: 3021: 3016: 3011: 3006: 3001: 2995: 2993: 2987: 2986: 2984: 2983: 2978: 2973: 2968: 2963: 2958: 2953: 2948: 2943: 2938: 2933: 2928: 2923: 2918: 2913: 2908: 2903: 2898: 2893: 2888: 2882: 2880: 2874: 2873: 2861: 2860: 2853: 2846: 2838: 2832: 2831: 2823: 2811: 2782: 2724: 2686:(12): 5463–7. 2670:; Nicklen, S; 2664: 2636:(2): 709–714. 2613: 2608: 2603: 2598: 2545: 2540: 2512:(2): 137–158. 2493: 2488: 2476: 2471: 2466: 2461: 2456: 2443: 2435: 2434: 2389:external links 2384: 2382: 2375: 2369: 2368:External links 2366: 2365: 2364: 2339: 2336: 2334: 2333: 2281: 2224: 2189:(5350): 82–8. 2173: 2130: 2111:(6): 514–520. 2091: 2052:(7): 671–682. 2028: 1979: 1940:(9): 253–264. 1920: 1877: 1870: 1852: 1803: 1782:(6): 669–681. 1762: 1703: 1654: 1650:Mukherjee 2016 1639: 1632: 1612: 1593:(4): 375–411. 1577: 1535: 1501: 1486: 1465: 1458: 1440: 1431: 1419: 1407: 1392: 1371: 1356: 1338: 1320: 1313: 1295: 1288: 1258: 1243: 1220: 1205: 1176: 1174: 1171: 1170: 1169: 1164: 1159: 1154: 1149: 1144: 1137: 1134: 1108:Walter Gilbert 1082:coat protein. 1029:showed in 1944 1026:Maclyn McCarty 1016:" hypothesis. 952:sex chromosome 907: 904: 886: 883: 862:develop afresh 846: 843: 839:Francis Galton 799:Charles Darwin 790: 787: 785: 782: 717: 714: 683:Charles Naudin 656: 653: 625:Main article: 607: 604: 594:. In 1140 CE, 578:Arab physician 517: 514: 502: 499: 414:William Harvey 406:ancient Greece 358: 357: 355: 354: 347: 340: 332: 329: 328: 327: 326: 310: 309: 306: 305: 299: 296: 295: 292: 291: 286: 285: 280: 275: 270: 265: 263:Immunogenetics 260: 255: 250: 245: 239: 238: 237: 234: 233: 230: 229: 226: 225: 218: 217: 212: 195: 190: 188:DNA sequencing 185: 179: 176: 175: 172: 171: 168: 167: 162: 157: 152: 147: 137: 132: 126: 123: 122: 119: 118: 115: 114: 109: 100: 99: 94: 89: 84: 79: 74: 69: 64: 59: 54: 48: 47: 46: 44:Key components 43: 42: 39: 38: 30: 29: 23: 22: 9: 6: 4: 3: 2: 4070: 4059: 4056: 4054: 4053:Gregor Mendel 4051: 4049: 4046: 4044: 4041: 4039: 4036: 4035: 4033: 4018: 4010: 4009: 4006: 4000: 3997: 3995: 3992: 3991: 3989: 3985: 3979: 3976: 3974: 3971: 3969: 3966: 3964: 3961: 3959: 3956: 3954: 3951: 3949: 3946: 3944: 3941: 3939: 3936: 3934: 3931: 3929: 3926: 3924: 3921: 3919: 3916: 3914: 3911: 3909: 3906: 3904: 3901: 3899: 3896: 3894: 3891: 3890: 3888: 3884: 3878: 3875: 3873: 3870: 3868: 3865: 3863: 3860: 3858: 3855: 3853: 3850: 3848: 3845: 3844: 3842: 3839: 3835: 3829: 3826: 3824: 3821: 3819: 3816: 3814: 3811: 3809: 3806: 3804: 3801: 3799: 3796: 3794: 3791: 3789: 3786: 3785: 3783: 3779: 3773: 3770: 3768: 3765: 3763: 3760: 3758: 3755: 3753: 3750: 3748: 3745: 3743: 3740: 3738: 3735: 3733: 3730: 3728: 3725: 3724: 3722: 3718: 3712: 3709: 3707: 3704: 3702: 3699: 3697: 3694: 3692: 3689: 3687: 3684: 3683: 3680: 3676: 3669: 3664: 3662: 3657: 3655: 3650: 3649: 3646: 3634: 3626: 3625: 3622: 3616: 3613: 3611: 3608: 3606: 3603: 3601: 3600:Poliomyelitis 3598: 3596: 3593: 3591: 3588: 3586: 3583: 3581: 3578: 3576: 3573: 3572: 3570: 3566: 3560: 3557: 3553: 3552: 3548: 3547: 3546: 3543: 3541: 3538: 3536: 3533: 3531: 3528: 3526: 3523: 3521: 3518: 3514: 3513: 3509: 3508: 3507: 3504: 3503: 3501: 3497: 3491: 3488: 3486: 3483: 3481: 3478: 3476: 3473: 3471: 3468: 3464: 3461: 3460: 3459: 3458:Ancient Egypt 3456: 3454: 3451: 3449: 3446: 3444: 3441: 3440: 3438: 3434: 3428: 3425: 3423: 3420: 3416: 3415:Psychosurgery 3413: 3411: 3408: 3406: 3405: 3401: 3400: 3399: 3396: 3394: 3391: 3389: 3388:Endocrinology 3386: 3382: 3379: 3378: 3377: 3374: 3372: 3369: 3367: 3364: 3362: 3359: 3357: 3354: 3350: 3347: 3345: 3342: 3341: 3340: 3337: 3335: 3332: 3331: 3329: 3327: 3324:Histories of 3322: 3317: 3307: 3304: 3302: 3299: 3297: 3294: 3292: 3289: 3287: 3284: 3282: 3279: 3277: 3274: 3272: 3269: 3267: 3264: 3262: 3259: 3255: 3254: 3250: 3249: 3248: 3245: 3243: 3240: 3238: 3235: 3233: 3230: 3228: 3227:Biotechnology 3225: 3223: 3220: 3218: 3215: 3213: 3210: 3209: 3207: 3203: 3199: 3198: 3192: 3188: 3181: 3176: 3174: 3169: 3167: 3162: 3161: 3158: 3146: 3138: 3137: 3134: 3128: 3125: 3123: 3120: 3118: 3115: 3113: 3110: 3108: 3105: 3103: 3100: 3098: 3095: 3093: 3090: 3088: 3085: 3083: 3080: 3076: 3073: 3072: 3071: 3068: 3066: 3063: 3062: 3060: 3056: 3050: 3047: 3045: 3042: 3040: 3037: 3035: 3032: 3030: 3027: 3025: 3022: 3020: 3017: 3015: 3012: 3010: 3007: 3005: 3002: 3000: 2997: 2996: 2994: 2988: 2982: 2979: 2977: 2974: 2972: 2969: 2967: 2964: 2962: 2959: 2957: 2954: 2952: 2949: 2947: 2944: 2942: 2939: 2937: 2934: 2932: 2929: 2927: 2924: 2922: 2919: 2917: 2914: 2912: 2909: 2907: 2904: 2902: 2901:Biotechnology 2899: 2897: 2894: 2892: 2889: 2887: 2884: 2883: 2881: 2875: 2870: 2866: 2859: 2854: 2852: 2847: 2845: 2840: 2839: 2836: 2828: 2824: 2820: 2816: 2812: 2808: 2804: 2800: 2796: 2792: 2788: 2783: 2779: 2775: 2771: 2767: 2762: 2757: 2753: 2749: 2745: 2741: 2737: 2733: 2730:; Wilson, V; 2729: 2725: 2721: 2717: 2712: 2707: 2702: 2697: 2693: 2689: 2685: 2681: 2677: 2673: 2669: 2665: 2661: 2657: 2652: 2647: 2643: 2639: 2635: 2631: 2627: 2625: 2621: 2614: 2612: 2609: 2607: 2604: 2602: 2599: 2595: 2591: 2586: 2581: 2576: 2571: 2567: 2563: 2560:(8): 748–55. 2559: 2555: 2551: 2546: 2544: 2541: 2537: 2533: 2528: 2523: 2519: 2515: 2511: 2507: 2503: 2501: 2494: 2492: 2489: 2485: 2481: 2477: 2475: 2472: 2470: 2467: 2465: 2462: 2460: 2457: 2453: 2449: 2444: 2442: 2439: 2438: 2431: 2428: 2420: 2410: 2406: 2405:inappropriate 2402: 2398: 2392: 2390: 2383: 2374: 2373: 2363: 2362:0-87969-675-3 2359: 2355: 2351: 2348: 2347: 2345: 2329: 2325: 2321: 2317: 2312: 2307: 2303: 2299: 2295: 2292:(June 2007). 2291: 2285: 2277: 2273: 2269: 2265: 2260: 2255: 2251: 2247: 2243: 2239: 2235: 2228: 2220: 2216: 2212: 2208: 2204: 2200: 2196: 2192: 2188: 2184: 2177: 2169: 2165: 2161: 2157: 2153: 2149: 2145: 2141: 2134: 2126: 2122: 2118: 2114: 2110: 2106: 2102: 2095: 2087: 2083: 2078: 2073: 2068: 2063: 2059: 2055: 2051: 2047: 2043: 2041: 2032: 2024: 2020: 2015: 2010: 2006: 2002: 1998: 1994: 1993:Microbiol Rev 1990: 1983: 1975: 1971: 1966: 1961: 1956: 1951: 1947: 1943: 1939: 1935: 1931: 1924: 1916: 1912: 1908: 1904: 1900: 1896: 1892: 1888: 1881: 1873: 1867: 1863: 1856: 1848: 1844: 1839: 1834: 1830: 1826: 1823:(2): 379–84. 1822: 1818: 1814: 1807: 1799: 1795: 1790: 1785: 1781: 1777: 1773: 1766: 1758: 1754: 1749: 1744: 1739: 1734: 1730: 1726: 1722: 1718: 1714: 1707: 1699: 1695: 1690: 1685: 1681: 1677: 1673: 1669: 1668:J Gen Physiol 1665: 1658: 1651: 1646: 1644: 1635: 1629: 1625: 1624: 1616: 1608: 1604: 1600: 1596: 1592: 1588: 1581: 1573: 1569: 1565: 1561: 1558:(78): 502–3. 1557: 1553: 1549: 1545: 1539: 1524: 1520: 1516: 1512: 1505: 1497: 1493: 1489: 1483: 1479: 1475: 1469: 1461: 1455: 1451: 1444: 1435: 1428: 1423: 1416: 1411: 1403: 1399: 1395: 1389: 1385: 1381: 1375: 1367: 1363: 1359: 1357:3-10-035601-2 1353: 1349: 1342: 1335: 1330: 1324: 1316: 1310: 1306: 1299: 1291: 1285: 1281: 1277: 1273: 1269: 1262: 1254: 1250: 1246: 1240: 1236: 1235: 1230: 1224: 1216: 1212: 1208: 1202: 1198: 1194: 1190: 1184: 1182: 1177: 1168: 1165: 1163: 1160: 1158: 1155: 1153: 1150: 1148: 1145: 1143: 1140: 1139: 1133: 1131: 1127: 1124: 1120: 1116: 1111: 1109: 1105: 1101: 1097: 1093: 1089: 1088:Phillip Sharp 1085: 1081: 1077: 1073: 1068: 1064: 1062: 1058: 1054: 1050: 1046: 1042: 1041:Francis Crick 1038: 1034: 1030: 1027: 1023: 1019: 1015: 1011: 1007: 1003: 999: 994: 992: 988: 984: 980: 978: 973: 969: 965: 961: 953: 949: 945: 944: 939: 935: 931: 927: 925: 922:in his work " 921: 920:Ronald Fisher 917: 913: 903: 900: 896: 891: 890:Hugo de Vries 882: 880: 876: 871: 863: 859: 855: 851: 842: 840: 836: 832: 828: 825:'s theory of 824: 820: 812: 808: 804: 800: 795: 781: 779: 775: 773: 762: 758: 754: 750: 746: 744: 740: 735: 734:Pisum sativum 731: 730:Gregor Mendel 722: 713: 711: 707: 703: 699: 694: 692: 688: 684: 680: 676: 672: 668: 662: 652: 650: 646: 642: 638: 634: 628: 620: 616: 612: 603: 601: 597: 593: 592: 587: 583: 579: 574: 571: 567: 566:fixed essence 563: 558: 554: 550: 546: 542: 538: 530: 526: 522: 512: 508: 498: 496: 492: 488: 482: 480: 475: 471: 466: 464: 460: 456: 452: 448: 447: 442: 438: 434: 430: 429:Hugo de Vries 425: 423: 420:contradicted 419: 415: 411: 407: 402: 400: 396: 392: 389: 385: 381: 377: 373: 369: 368:classical era 365: 353: 348: 346: 341: 339: 334: 333: 331: 330: 324: 314: 313: 312: 311: 304: 301: 300: 294: 293: 284: 281: 279: 276: 274: 271: 269: 266: 264: 261: 259: 256: 254: 251: 249: 246: 244: 241: 240: 232: 231: 224: 221: 220: 216: 213: 209: 200: 196: 194: 191: 189: 186: 184: 181: 180: 174: 173: 166: 163: 161: 158: 156: 153: 151: 148: 145: 141: 138: 136: 133: 131: 128: 127: 121: 120: 113: 110: 108: 105: 104: 98: 95: 93: 90: 88: 85: 83: 80: 78: 75: 73: 70: 68: 65: 63: 60: 58: 55: 53: 50: 49: 41: 40: 36: 32: 31: 28: 25: 24: 20: 19: 16: 3918:Genetic code 3852:the Americas 3828:Quantitative 3798:Cytogenetics 3793:Conservation 3695: 3686:Introduction 3615:Tuberculosis 3549: 3530:Neuroimaging 3510: 3480:Ancient Rome 3475:Ancient Iran 3402: 3291:Pharmacology 3276:Neuroscience 3266:Microbiology 3251: 3241: 3217:Biochemistry 3195: 2956:Paleontology 2920: 2896:Biochemistry 2818: 2790: 2786: 2743: 2739: 2728:Jeffreys, AJ 2683: 2679: 2633: 2629: 2623: 2619: 2557: 2553: 2509: 2505: 2500:Pneumococcus 2499: 2483: 2451: 2423: 2417:January 2023 2414: 2399:by removing 2386: 2353: 2301: 2297: 2284: 2241: 2237: 2227: 2186: 2182: 2176: 2143: 2139: 2133: 2108: 2104: 2094: 2049: 2045: 2039: 2031: 1999:(1): 72–98. 1996: 1992: 1982: 1937: 1933: 1923: 1890: 1886: 1880: 1861: 1855: 1820: 1816: 1806: 1779: 1775: 1765: 1720: 1716: 1706: 1674:(1): 39–56. 1671: 1667: 1657: 1622: 1615: 1590: 1586: 1580: 1555: 1551: 1548:"Pangenesis" 1544:Darwin, C.R. 1538: 1526:. 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Scribner. 1477: 1468: 1449: 1443: 1434: 1422: 1410: 1383: 1374: 1347: 1341: 1328: 1323: 1304: 1298: 1271: 1261: 1233: 1223: 1196: 1112: 1072:Walter Fiers 1069: 1065: 1061:retroviruses 1018:Oswald Avery 995: 975: 957: 941: 909: 895:Carl Correns 888: 867: 816: 777: 769: 767: 747: 733: 727: 695: 691:back-crosses 664: 630: 596:Judah HaLevi 589: 575: 560:century—the 534: 487:genetic code 483: 467: 444: 433:Carl Correns 426: 417: 410:Early Modern 403: 363: 361: 283:Quantitative 253:Cytogenetics 248:Conservation 134: 130:Introduction 15: 3898:Epigenetics 3575:Black Death 3506:Antibiotics 3371:Dermatology 3082:Ethnobotany 2971:RNA biology 2879:disciplines 2793:: 599–629. 2672:Coulson, AR 1652:, Chapter 5 1528:11 November 1229:Mayr, Ernst 1167:Phage group 964:chromosomes 950:was on the 936:discovered 797:Diagram of 586:haemophilia 537:Hippocrates 376:Hippocrates 4032:Categories 3903:Geneticist 3877:South Asia 3823:Population 3803:Ecological 3772:Amino acid 3752:Nucleotide 3727:Chromosome 3559:Wound care 3453:Byzantinia 3443:Prehistory 3398:Psychiatry 3339:Anesthesia 3296:Physiology 3247:Immunology 3237:Embryology 3024:Lamarckism 2931:Immunology 2502:Type III " 2342:See also: 1393:3437203290 1380:Jahn, Ilse 1366:1200295370 1244:0674364457 1173:References 943:Drosophila 938:sex linked 879:germ plasm 875:Lamarckism 845:Germ plasm 835:pangenesis 831:Lamarckian 811:Lamarckism 789:Pangenesis 659:See also: 645:epigenesis 633:Anaxagoras 600:The Kuzari 549:pangenesis 545:Anaxagoras 505:See also: 372:Pythagoras 278:Population 258:Ecological 183:Geneticist 97:Amino acid 77:Nucleotide 52:Chromosome 3818:Molecular 3813:Microbial 3788:Classical 3590:Pandemics 3393:Neurology 3349:Neuraxial 3286:Pathology 3281:Nutrition 3232:Chemistry 3092:Dysgenics 3075:Teleology 3039:RNA world 3034:Protocell 3009:Darwinism 2990:Theories, 2961:Phycology 2732:Thein, SL 2668:Sanger, F 2506:J Exp Med 2401:excessive 2290:Pennisi E 1523:1059-1028 1496:949803912 1427:Mayr 1982 1415:Mayr 1982 1334:Ibn Tibon 1215:276334688 1126:evolution 1123:Darwinian 1104:continuum 1070:In 1972, 958:In 1910, 827:evolution 706:dominance 698:varieties 591:Al-Tasrif 541:Aristotle 463:evolution 455:Mendelian 449:. Led by 416:'s book 395:His works 380:Aristotle 273:Molecular 268:Microbial 243:Classical 144:molecular 140:Evolution 4043:Genetics 4017:Category 3943:Heredity 3913:Genomics 3757:Mutation 3747:Heredity 3711:Glossary 3701:Timeline 3675:Genetics 3633:Category 3610:Syphilis 3605:Smallpox 3551:Timeline 3545:Vaccines 3525:Humorism 3512:Timeline 3404:Timeline 3301:Virology 3253:Timeline 3242:Genetics 3145:Category 3087:Eugenics 2992:concepts 2936:Medicine 2921:Genetics 2869:timeline 2734:(1985). 2660:18927256 2630:Genetics 2594:16589553 2536:19871359 2328:36463252 2320:17569836 2268:16724031 2168:13882203 2125:15999435 2105:C R Biol 2086:16590258 1974:16588748 1915:13054692 1798:17567988 1757:16588492 1698:12981234 1402:19780133 1231:(1982). 1191:(2010). 1136:See also 1115:genetics 991:bacteria 974:, using 972:fly room 868:In 1883 803:gemmules 671:Linnaeus 667:taxonomy 649:Ontogeny 570:Epicurus 507:Heredity 441:genetics 384:Epicurus 323:Category 208:template 199:Genomics 177:Research 82:Mutation 72:Heredity 27:Genetics 3696:History 3691:Outline 3585:Malaria 3448:Babylon 3422:Surgery 3344:General 3306:Viruses 3222:Biology 3212:Anatomy 3058:Related 2926:Geology 2911:Ecology 2891:Anatomy 2877:Fields, 2807:2427016 2778:4229883 2770:2989708 2748:Bibcode 2688:Bibcode 2651:2567374 2620:hisB463 2562:Bibcode 2527:2135445 2486:. 2000. 2395:Please 2387:use of 2298:Science 2276:4420674 2246:Bibcode 2219:4153893 2211:4555447 2191:Bibcode 2148:Bibcode 2054:Bibcode 2023:6261109 1965:1079044 1942:Bibcode 1895:Bibcode 1847:8294854 1838:2191359 1748:1078370 1725:Bibcode 1689:2147348 1607:4908353 1560:Bibcode 1253:7875904 1100:regions 1092:genomes 916:Pearson 776:in the 687:hybrids 588:in his 412:times, 135:History 107:Outline 3862:Europe 3847:Africa 3781:Fields 3767:Allele 3742:Genome 3595:Plague 3356:Cancer 2906:Botany 2805:  2776:  2768:  2740:Nature 2720:271968 2718:  2711:431765 2708:  2658:  2648:  2592:  2585:534157 2582:  2534:  2524:  2360:  2326:  2318:  2274:  2266:  2238:Nature 2217:  2209:  2183:Nature 2166:  2140:Nature 2123:  2084:  2077:528642 2074:  2021:  2014:281499 2011:  1972:  1962:  1913:  1887:Nature 1868:  1845:  1835:  1796:  1755:  1745:  1696:  1686:  1630:  1605:  1552:Nature 1521:  1494:  1484:  1456:  1400:  1390:  1364:  1354:  1311:  1286:  1251:  1241:  1213:  1203:  1024:, and 858:gonads 823:Darwin 807:gonads 716:Mendel 681:, and 615:Sperms 321:  235:Fields 92:Allele 67:Genome 3987:Lists 3867:Italy 3706:Index 2774:S2CID 2618:"The 2324:S2CID 2272:S2CID 2215:S2CID 1515:Wired 637:sperm 112:Index 2803:PMID 2766:PMID 2716:PMID 2656:PMID 2590:PMID 2532:PMID 2358:ISBN 2316:PMID 2264:PMID 2207:PMID 2164:PMID 2121:PMID 2082:PMID 2019:PMID 1970:PMID 1911:PMID 1866:ISBN 1843:PMID 1794:PMID 1753:PMID 1694:PMID 1628:ISBN 1603:PMID 1591:XXIV 1530:2019 1519:ISSN 1492:OCLC 1482:ISBN 1454:ISBN 1398:OCLC 1388:ISBN 1362:OCLC 1352:ISBN 1309:ISBN 1284:ISBN 1249:OCLC 1239:ISBN 1211:OCLC 1201:ISBN 1086:and 1039:and 1004:and 948:gene 914:and 621:1695 539:and 529:form 509:and 470:gene 435:and 362:The 3737:RNA 3732:DNA 3381:CPR 2819:CNN 2795:doi 2756:doi 2744:316 2706:PMC 2696:doi 2646:PMC 2638:doi 2634:180 2580:PMC 2570:doi 2522:PMC 2514:doi 2484:BBC 2403:or 2306:doi 2302:316 2254:doi 2242:441 2199:doi 2187:237 2156:doi 2144:192 2113:doi 2109:328 2072:PMC 2062:doi 2009:PMC 2001:doi 1960:PMC 1950:doi 1903:doi 1891:171 1833:PMC 1825:doi 1821:179 1784:doi 1743:PMC 1733:doi 1684:PMC 1676:doi 1595:doi 1568:doi 1276:doi 1096:DNA 1059:in 1053:RNA 1045:DNA 998:DNA 926:". 641:egg 474:DNA 404:In 401:. 62:RNA 57:DNA 4034:: 3840:of 2817:. 2801:. 2791:55 2789:. 2772:. 2764:. 2754:. 2742:. 2738:. 2714:. 2704:. 2694:. 2684:74 2682:. 2678:. 2654:. 2644:. 2632:. 2628:. 2588:. 2578:. 2568:. 2558:40 2556:. 2552:. 2530:. 2520:. 2510:79 2508:. 2504:. 2482:. 2450:. 2352:, 2322:. 2314:. 2300:. 2296:. 2270:. 2262:. 2252:. 2240:. 2236:. 2213:. 2205:. 2197:. 2185:. 2162:. 2154:. 2142:. 2119:. 2107:. 2103:. 2080:. 2070:. 2060:. 2050:44 2048:. 2044:. 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Index

Genetics

Chromosome
DNA
RNA
Genome
Heredity
Nucleotide
Mutation
Genetic variation
Allele
Amino acid
Outline
Index
Introduction
History
Evolution
molecular
Population genetics
Mendelian inheritance
Quantitative genetics
Molecular genetics
Geneticist
DNA sequencing
Genetic engineering
Genomics
template
Medical genetics
Branches of genetics
Classical

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