51:
252:(LMS) railway lineâ, and his mother, Barbara (nĂ©e Lindsay) came from a farming background. His parents, he and his younger brother lived in a two-room tenement, in which the âbestâ room, as was the custom then, was never used, so the family essentially lived in a single room.
307:, which were first known as fungal metabolites. In the 1950s the search began at the ICI Akers Research Labs to see if they existed in higher plants. A multidisciplinary team was involved in the effort, with Margaret Radler discovering that immature seeds of runner beans (
493:
Anneliese (Anne) Levy was born in 1925; her family were refugees from
Germany in the mid-1930s. She studied for her PhD at The Frythe, where she and Jake met. After the move to Bristol Anne worked as a Biology teacher at the former Westwing School,
388:
Again with funding from AFRC, Jake MacMillan was able to take up research at LARS âworking at the bench and learning new methods in enzymology and molecular biology for the first three years he spent six months each year in Bernie
Phinneyâs lab at
466:
Frances
Margaret. Frankie M MacMillan is Professor of Biomedical Science Education in the School of Physiology, Pharmacology & Neuroscience at the University of Bristol; she was awarded the 2024 Otto Hutter Teaching Prize Lecture by
263:
in 1942, to read chemistry, natural philosophy and mathematics in the first year, and chemistry and botany in the second; he graduated in 1946 with first class honours. He went on to obtain a postgraduate studentship from the
378:(AFRC) eased the day-to-day running of the group. He formally retired in 1990 but was able to continue for another year, taking care not to interfere with the work of his successor Thomas J Simpson, FRS.
311:) were a relatively rich source (ca 0.25 ÎŒg/g). With the help of local growers about 2 metric tons of beans were processed, eventually yielding milligram quantities of Gibberellin A
228:, was a British scientist who worked at the interface between biology and chemistry. He "became renowned for his work on isolating, naming and determining the chemical structure of
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After gaining his PhD in 1948, MacMillan was not attracted to academia, especially with its low salaries. Instead, âas luck would have it an ideal position with
371:, Ottawa, in 1967, and published in 1969. There he met and developed a life-long collaboration with Nobutaka Takahashi, leading to several visits to Japan.
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Binks, R; MacMillan, J; Pryce, R J (1969). "Plant hormonesâVIII: combined gas chromatography-mass spectrometry of methyl esters of gibberellins A
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854:
714:
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Jake MacMillan was appointed a lecturer at
Bristol in 1963. He and a colleague, Bob Binks, worked on the relatively new technique of
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to identify a range of gibberellins. The results were presented at the Sixth
International Conference on Plant Growth Substances at
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In 2003 MacMillan returned to the School of
Chemistry, University of Bristol, as Emeritus Professor and Senior Research Fellow.
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349:. He did not enjoy this time away from research, and decided to apply for an academic post, despite the large cut in salary.
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His final years at ICI were spent in overseeing the move of Akers staff to the newly-established
Pharmaceutical Division at
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John MacMillan married
Anneliese Levy on 20 December 1952 in the Hendon registration district. They had three children:
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284:(ICI) fell into my lapâ. He joined a small, high-powered group of organic chemists and microbiologists at The Frythe in
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248:, and lived there for his first 10 years. His father, John, like his grandfather, was a âsignalman on the old
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Susan Janet, who held various postdoctoral positions in the UK and North
America in Neuroscience (including
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281:
393:â. He also wrote reviews and many papers in the period 1990-2004. Overall, he published about 400 papers.
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338:(ACS). MacMillan made a second trip to the USA in 1960, to attend the 138th ACS meeting in New York.
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Buchanan, G L; Cook, J W; Loudon, J D; MacMillan, J (1948). "Synthesis of
Colchicine Derivatives".
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MacMillan became head of the Department of Organic Chemistry in 1983. Long-term funding from the
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Elected Distinguished Foreign Scholar of Mid-America Association of State Universities (1987)
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268:(DSIR), enabling him to continue as a PhD student in Glasgow. He worked on the structure of
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232:, which regulate growth and influence processes such as stem elongation and germination".
8:
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Elected Honorary Member of the Japanese Society for Chemical Regulation in Plants (1987)
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was organised in 1957, at which MacMillan presented a paper. On the same trip he met
765:"Professor Frankie MacMillan receives teaching prize from the Physiological Society"
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272:, and was supervised by Dr J D Loudon. The results were published in four papers.
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Elected Corresponding Member of the American Society of Plant Physiology (1978)
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President of the International Plant Growth Substance Association (1973-1976)
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University of Bristol: School of Physiology, Pharmacology and Neuroscience
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Royal Society of Chemistry Hugo-Muller Lecturership and Medal (1988-1989)
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Research Medal, International Plant Growth Substance Association (1982)
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American Society of Plant Physiology, Charles Reid Barnes Award (1988)
319:). More gibberellins were to follow and their structures determined.
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Royal Society of Chemistry Award in Natural Product Chemistry (1988)
288:, aiming to find potential pharmaceuticals in fungi. This resulted,
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There was growing international interest in these compounds, and a
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Elected Honorary Member of the Botanical Society of America (1989)
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MacMillan, Jake (1996). "Reflections of a Bio-organic Chemist".
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Personal communication from Professor F M MacMillan, 7 June 2023
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Chemistry Tree: The Academic Genealogy of Chemistry Researchers
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Foreign Associate of the US National Academy of Sciences (1991)
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259:. Here he became very interested in chemistry and entered the
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Properties and structures of griseofulvins and gibberellins
334:, and then to New York to attend the 132nd Meeting of the
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MacMillanâs next project at ICI was on the plant hormones
572:"John (Jake) Macmillan. 13 September 1924â12 May 2014"
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Biographical Memoirs of Fellows of the Royal Society
345:, and the transfer of The Frythe to its new owners,
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Wilson Baker Lecturer, University of Bristol (1990)
255:MacMillan gained a place in the top entry form at
570:Simpson, Thomas J.; Willis, Christine L. (2020).
409:Flintoff Medal, Royal Society of Chemistry (1978)
240:John MacMillan was born on 13 September 1924 in
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266:Department of Scientific and Industrial Research
330:, flew to California to meet Bernie Phinney at
486:Jake died on 12 May 2014 and was cremated in
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514:"Life in brief: Professor Jake MacMillan".
363:(GC) in combination with mass spectrometry
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415:Elected Fellow of the Royal Society (1978)
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548:Annu. Rev. Plant Physiol. Plant Mol. Biol
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830:People educated at Lanark Grammar School
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376:Agricultural and Food Research Council
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296:spp. of the potent fungistatic agent
27:Scottish organic chemist (1924â2014)
855:Alumni of the University of Glasgow
617:"The Frythe, Welwyn, Hertfordshire"
518:. London. 11 June 2014. p. 52.
445:Pergamon Phytochemical Prize (1995)
383:Long Ashton Research Station (LARS)
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673:and their trimethylsilyl ethers".
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642:"Bernard Orin Phinney 1917â2009"
840:21st-century British biologists
835:20th-century British biologists
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715:"Jake MacMillan - Publications"
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740:"Hendon Registration District"
693:"Professor Thomas Simpson FRS"
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224:(1924â2014), always known as
790:"Westwing School, Thornbury"
461:The Beit Memorial Fellowship
282:Imperial Chemical Industries
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183:Long Ashton Research Station
175:Imperial Chemical Industries
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463:) before starting a family.
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309:Phaseolus multiflorus
261:University of Glasgow
257:Lanark Grammar School
177:University of Bristol
136:Anneliese (Anne) Levy
119:University of Glasgow
109:Lanark Grammar School
18:John (Jake) MacMillan
703:on 17 November 2015.
482:science in Bristol.
369:Carleton University
794:Avon Gardens Trust
400:Awards and honours
361:gas chromatography
615:Knaggs, Jeffery.
324:Gordon Conference
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158:Scientific career
72:13 September 1924
16:(Redirected from
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90:(aged 89)
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172:Institutions
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99:Pucklechurch
88:(2014-05-12)
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825:2014 deaths
820:1924 births
621:Jeff Knaggs
593:For example
294:Penicillium
246:Lanarkshire
86:12 May 2014
814:Categories
695:. London:
554:(1): 1â21.
502:References
290:inter alia
270:colchicine
206:J D Loudon
68:1924-09-13
516:The Times
496:Thornbury
236:Biography
105:Education
347:Unilever
332:Stanford
152:See list
141:Children
799:13 June
774:12 June
749:16 June
724:12 June
650:10 June
480:A Level
626:9 June
604:: 692.
598:Nature
451:Family
286:Welwyn
242:Wishaw
195:(1948)
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189:Thesis
164:Fields
149:Awards
133:Spouse
76:Wishaw
744:UKBMD
645:(PDF)
365:GC-MS
801:2023
776:2023
751:2023
726:2023
669:to A
652:2023
628:2023
478:and
476:GCSE
391:UCLA
180:UCLA
83:Died
58:Born
602:162
315:(GA
276:ICI
221:FRS
41:FRS
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
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