135:
757:
734:
66:
1154:(TdP), a heart rhythm disturbance that is sometimes fatal. Despite the observed change in the QT interval, the risk of TdP from escitalopram appears to be quite low, and it is similar to other antidepressants that are not known to affect QT interval. A 2013 review discusses several reasons to be optimistic about the safety of escitalopram. It references a crossover study in which 113 subjects were each given four different treatments in randomized order: placebo, 10 mg/day escitalopram, 30 mg/day escitalopram, or 400 mg/day
1597:, a known strong CYP2D6 inhibitor, has been found to significantly increase citalopram plasma concentration and systemic exposure (peak levels increased by 30%, total exposure increased by 40%); as of April 2018 the interaction with escitalopram had not been studied, but some monographs warned of the potential interaction. Citalopram did not affect the pharmacokinetics of bupropion or its metabolites in the study.
57:
10891:
2015:
1465:(by <0.4 points). Antidepressant exposure is not associated with an increased risk of spontaneous abortion. There is a tentative association of SSRI use during pregnancy with heart problems in the baby. The advantages of their use during pregnancy may thus not outweigh the possible negative effects on the baby.
1227:. Hyponatremia especially affects the elderly, women, those with cardiovascular comorbidities, those with low body weight, and those taking other medications that cause hyponatremia. This is typically not dose dependent and at higher risk for occurrence within the first few weeks of starting treatment.
2081:
In 2004, separate civil suits alleging illegal marketing of citalopram and escitalopram for use by children and teenagers by Forest were initiated by two whistleblowers: a physician named Joseph
Piacentile and a Forest salesman named Christopher Gobble. In February 2009, the suits were joined. Eleven
1179:
had less risk), and it ranked 5th of 9 by TdP incidence in patients ages 18-64. Antidepressants as a class had a relatively low risk of TdP, and most patients on an antidepressant who experienced TdP were also taking another drug that prolongs QT interval. Specifically, 80% of the escitalopram users
1063:
Controversy existed regarding the effectiveness of escitalopram compared with its predecessor, citalopram. The importance of this issue followed from the greater cost of escitalopram relative to the generic mixture of isomers of citalopram, prior to the expiration of the escitalopram patent in 2012,
1170:
More data about the cardiac risk from escitalopram can be found in a large observational study from Sweden that took note of all the medications used by all the patients presenting with TdP, and found the incidence of TdP in escitalopram users to be only 0.7 cases of TdP for every 100,000 patients
1139:
among the adults treated with escitalopram for psychiatric indications. The authors of a related study note the general problem with statistical approaches: due to the rarity of suicidal events in clinical trials, it is hard to draw firm conclusions with a sample smaller than two million patients.
1427:(44%), muscle tension (44%), chills (44%), confusion or trouble concentrating (40%), amnesia (28%), and crying (28%). Very slow tapering was recommended. There have been spontaneous reports of discontinuation of Lexapro and other SSRIs and SNRIs, especially when abrupt, leading to dysphoric mood,
2072:
In 2006, Forest
Laboratories was granted an 828-day (2 years and 3 months) extension on its US patent for escitalopram. This pushed the patent expiration date from 7 December 2009, to 14 September 2011. Together with the 6-month pediatric exclusivity, the final expiration date was 14 March 2012.
1162:
known to cause QTc prolongation). At 10 mg/day, escitalopram increased the QTc interval by 4.5 milliseconds (ms). At 30 mg/day, the QTc increased by 10.7 ms. A QTc increase of less than 60 ms is not likely to confer significant risk. The 30 mg/day escitalopram dose induced significantly less QTc
2089:
to physicians to induce them to prescribe
Lexapro to children; and conducted so-called "seeding studies" that were, in reality, marketing efforts to promote the drug's use by doctors. Forest denied the allegations but ultimately agreed to settle with the plaintiffs for over $ 313 million.
3118:
Bech P, Lönn SL, Overø KF (February 2010). "Relapse prevention and residual symptoms: a closer analysis of placebo-controlled continuation studies with escitalopram in major depressive disorder, generalized anxiety disorder, social anxiety disorder, and obsessive-compulsive disorder".
1489:
may occur in some cases. Therapeutic blood levels of escitalopram are usually in the range of 20–80 μg/L but may reach 80–200 μg/L in the elderly, patients with hepatic dysfunction, those who are poor CYP2C19 metabolizers or following acute overdose. Monitoring of the drug in
1447:
Some people experience persistent sexual side effects when taking SSRIs or after discontinuing them. Symptoms of medication-induced sexual dysfunction from antidepressants include difficulty with orgasm, erection, or ejaculation. Other symptoms may be genital anesthesia,
1171:
who took the drug (ages 18-64), and only 4.1 cases of TdP for every 100,000 elderly patients who took the drug (ages 65 and up). Of the 9 antidepressants that were used by patients with TdP, escitalopram ranked 7th by TdP incidence in elderly patients (only
3027:
Sicras-Mainar A, Navarro-Artieda R, Blanca-Tamayo M, Gimeno-de la Fuente V, Salvatella-Pasant J (December 2010). "Comparison of escitalopram vs. citalopram and venlafaxine in the treatment of major depression in Spain: clinical and economic consequences".
2034:. Its development was initiated in 1997, and the resulting new drug application was submitted to the US FDA in March 2001. The short time (3.5 years) it took to develop escitalopram can be attributed to the previous experience of Lundbeck and Forest with
1068:. Accordingly, this issue has been examined in at least 10 different systematic reviews and meta analyses. As of 2012, reviews had concluded (with caveats in some cases) that escitalopram is modestly superior to citalopram in efficacy and tolerability.
4438:
Noehr-Jensen L, Zwisler ST, Larsen F, Sindrup SH, Damkier P, Brosen K (December 2009). "Escitalopram is a weak inhibitor of the CYP2D6-catalyzed O-demethylation of (+)-tramadol but does not reduce the hypoalgesic effect in experimental pain".
3964:"Unequal Sized Pupils Due to Escitalopram; Adverse Events to Dietary Supplements Causing Emergency Department Visits; Compulsive Masturbation Due to Pramipexole; Metformin-Induced Lactic Acidosis Masquerading As an Acute Myocardial Infarction"
2837:"Safety of 80 antidepressants, antipsychotics, anti-attention-deficit/hyperactivity medications and mood stabilizers in children and adolescents with psychiatric disorders: a large scale systematic meta-review of 78 adverse effects"
4288:
Ross LE, Grigoriadis S, Mamisashvili L, Vonderporten EH, Roerecke M, Rehm J, et al. (April 2013). "Selected pregnancy and delivery outcomes after exposure to antidepressant medication: a systematic review and meta-analysis".
2051:
Escitalopram is sold under many brand names worldwide such as
Cipralex, Lexapro, Lexam, Mozarin, Aciprex, Depralin, Ecytara, Elicea, Gatosil, Nexpram, Nexito, Nescital, Szetalo, Stalopam, Pramatis, Betesda, Scippa and Rexipra.
136:
1059:
Escitalopram is among the most effective and well-tolerated antidepressants for the short-term (acute) treatment of major depressive disorder in adults. It is also the safest one to give to children and adolescents.
4046:
Shen J, Hossain N, Streiner DL, Ravindran AV, Wang X, Deb P, et al. (November 2011). "Excessive daytime sleepiness and fatigue in depressed patients and therapeutic response of a sedating antidepressant".
2282:
1674:
Escitalopram can also prolong the QT interval, and hence it is not recommended in patients that are concurrently on other medications that also have the ability to prolong the QT interval. These drugs include
1207:
should be corrected before starting treatment. In
December 2011, the UK implemented new restrictions on the maximum daily doses at 20 mg for adults and 10 mg for those older than 65 years or with
1460:
Antidepressant exposure (including escitalopram) is associated with shorter duration of pregnancy (by three days), increased risk of preterm delivery (by 55%), lower birth weight (by 75 g), and lower
1390:
The most common effect is fatigue or somnolence, particularly in older adults, although patients with pre-existing daytime sleepiness and fatigue may experience paradoxical improvement of these symptoms.
2060:
The FDA issued the approval of escitalopram for major depression in August 2002, and for generalized anxiety disorder in
December 2003. In May 2006, the FDA approved a generic version of escitalopram by
4891:
Mansari ME, Wiborg O, Mnie-Filali O, Benturquia N, Sánchez C, Haddjeri N (February 2007). "Allosteric modulation of the effect of escitalopram, paroxetine and fluoxetine: in-vitro and in-vivo studies".
1954:
on the transporter, thereby decreasing its own disassociation rate. Escitalopram binds to this allosteric site at a greater affinity than other SSRIs. The clinical relevance of this action is unknown.
4856:
Zhong H, Haddjeri N, Sánchez C (January 2012). "Escitalopram, an antidepressant with an allosteric effect at the serotonin transporter--a review of current understanding of its mechanism of action".
3418:
Khan A, Schwartz K (2007). "Suicide risk and symptom reduction in patients assigned to placebo in duloxetine and escitalopram clinical trials: analysis of the FDA summary basis of approval reports".
5248:
7586:
4152:
Yasui-Furukori N, Hashimoto K, Tsuchimine S, Tomita T, Sugawara N, Ishioka M, et al. (June 2016). "Characteristics of
Escitalopram Discontinuation Syndrome: A Preliminary Study".
3560:
343:
2181:
3547:
In summary, the effects of citalopram and other antidepressants in therapeutic doses on QTc are not likely to be of clinical relevance unless other known risk factors are present.
2757:"Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis"
4335:
Gentile S (1 July 2015). "Early pregnancy exposure to selective serotonin reuptake inhibitors, risks of major structural malformations, and hypothesized teratogenic mechanisms".
2085:
The suits alleged that Forest illegally engaged in off-label promotion of
Lexapro for use in children; hid the results of a study showing lack of effectiveness in children; paid
3907:
4542:
3940:
9449:
10475:
10135:
9444:
2219:
2066:
2271:
3561:"FDA Drug Safety Communication: Revised recommendations for Celexa (citalopram hydrobromide) related to a potential risk of abnormal heart rhythms with high doses"
2992:
Favré P (February 2012). "" [Clinical efficacy and achievement of a complete remission in depression: Increasing interest in treatment with escitalopram].
1224:
1188:
with 52,750 users, and sotalol had a TdP incidence of 81.1 cases and 41.2 cases of TdP per 100,000 users in the ≥65 and 18-64 year-old demographics, respectively.
2214:[Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese).
7278:
5526:
2494:
9504:
7621:
298:
5092:
5026:
3638:"Citalopram and escitalopram: QT interval prolongation—new maximum daily dose restrictions (including in elderly patients), contraindications, and warnings"
9646:
5240:
3641:
2647:
1150:
prolongation, which is a measure of how rapidly the heart muscle repolarizes after each heartbeat. Prolongation of the QT interval is a risk factor for
826:
3313:"Antidepressants and Suicidality in Adults: Statistical Evaluation. (Presentation at Psychopharmacologic Drugs Advisory Committee; December 13, 2006)"
356:
3393:
3356:
2886:"Effectiveness and cost-effectiveness of antidepressants in primary care: a multiple treatment comparison meta-analysis and cost-effectiveness model"
1979:
penetrability. In a preclinical study in rats combining escitalopram with a P-glycoprotein inhibitor, its antidepressant-like effects were enhanced.
3877:
10951:
5412:
3322:
4626:
Brunton L, Chabner B, Knollman B. Goodman and Gilman's The
Pharmacological Basis of Therapeutics, Twelfth Edition. McGraw Hill Professional; 2010.
7114:
5493:
3645:
1135:. An analysis conducted by the FDA found a statistically insignificant 1.5 to 2.4-fold (depending on the statistical technique used) increase of
10734:
4378:
Haupt D (October 1996). "Determination of citalopram enantiomers in human plasma by liquid chromatographic separation on a Chiral-AGP column".
10288:
10243:
9855:
2521:
The selection and use of essential medicines 2023: web annex A: World Health
Organization model list of essential medicines: 23rd list (2023)
1452:, decreased libido, vaginal lubrication issues, and nipple insensitivity in women. Rates are unknown, and there is no established treatment.
1212:. The US Food and Drug Administration and Health Canada did not similarly order restrictions on escitalopram dosage, only on its predecessor
183:
2677:
10839:
10754:
10180:
9566:
9108:
9103:
8384:
8379:
8198:
7177:
6785:
6770:
6700:
6308:
5559:
2729:
855:
10844:
10769:
10719:
10390:
10125:
10103:
10078:
10068:
9913:
7271:
5001:
1946:(NET), making the side-effect profile relatively mild in comparison to less-selective SSRIs. In addition to its antagonist action at the
10465:
10415:
10357:
10352:
8887:
2434:
10679:
10674:
10669:
10664:
10445:
10258:
10028:
9484:
9225:
7616:
7611:
5310:
3899:
1593:
resulted in increased exposure to the escitalopram enantiomer, owing to the strong inhibition of CYP2C19 and CYP2D6 by these agents.
5194:
4534:
4082:
Rosekind MR, Gregory KB, Mallis MM (December 2006). "Alertness management in aviation operations: enhancing performance and sleep".
1581:, a CYP2C19 inhibitor. The authors of this study suggested that this increase is unlikely to be of clinical concern. Combination of
10694:
10689:
10684:
10575:
10570:
10450:
10155:
10053:
10048:
10033:
9968:
9963:
9710:
9609:
3929:
2122:
883:
InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3/t20-/m0/s1
10659:
10150:
9639:
7142:
6755:
5354:
5141:
5118:
5065:
4715:
Chae YJ, Jeon JH, Lee HJ, Kim IB, Choi JS, Sung KW, et al. (January 2014). "Escitalopram block of hERG potassium channels".
1951:
7123:
3286:
2707:
2244:
10644:
10639:
7606:
7264:
4195:
2464:
1113:
926:
290:
5241:"Drug Maker Forest Pleads Guilty; To Pay More Than $ 313 Million to Resolve Criminal Charges and False Claims Act Allegations"
7058:
6421:
6365:
4573:
2552:
1439:(psychomotor restlessness), mania, worsening of depression, and suicidal ideation can emerge when the dose is adjusted down.
1031:
in adults. In European countries and the United Kingdom, it is approved for depression and anxiety disorders; these include:
1008:
5218:
4644:
2018:
Cipralex brand escitalopram 10 mg package and tablet sheet. It is a reference escitalopram formulation, and was produced by
2211:
9593:
7107:
5592:
5165:
1628:
4932:"P-glycoprotein inhibition increases the brain distribution and antidepressant-like activity of escitalopram in rodents"
4568:. Philadelphia, Baltimore, New York, London, Buenos Aires, Hong Kong, Sydney, Tokyo: Lippincott Williams & Wilkins.
1927:, which is associated with an improvement in passive stress tolerance, and delayed downstream increase in expression of
900:
234:
10931:
9632:
7959:
5460:
4422:
2207:
1499:
2486:
10911:
4237:
2324:
Pastoor D, Gobburu J (January 2014). "Clinical pharmacology review of escitalopram for the treatment of depression".
1928:
1886:
1394:
Escitalopram has not been shown to affect serial reaction time, logical reasoning, serial subtraction, multitask, or
1195:
or known pre-existing QT interval prolongation, or in combination with other medicines that prolong the QT interval.
875:
10926:
9408:
7075:
6382:
9735:
5088:
5034:
2069:
decided in favor of Lundbeck regarding a patent infringement dispute and ruled the patent on escitalopram valid.
1015:
million prescriptions. In Australia, it was one of the top 10 most prescribed medications between 2017 and 2023.
527:
328:
215:
9775:
9613:
7100:
6495:
4196:"Lexapro (Escitalopram Oxalate) Drug Information: Warnings and Precautions - Prescribing Information at RxList"
2062:
1919:
of the neurotransmitter into the presynaptic neuron. Over time, this leads to a downregulation of pre-synaptic
1550:
by 40% and total exposure by 100%. Likewise, it has been found to increase peak levels of the CYP2D6 substrate
1191:
Drugs that prolong the QT interval, such as escitalopram, should be used with caution in those with congenital
4117:
Prakash O, Dhar V (June 2008). "Emergence of electric shock-like sensations on escitalopram discontinuation".
8669:
5303:
2625:
2212:"RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial"
1407:
1180:
who experienced TdP were taking at least one other drug known to cause TdP. For comparison, the most popular
1040:
3073:"Pharmacological treatments for generalised anxiety disorder: a systematic review and network meta-analysis"
10869:
9589:
7306:
7287:
6830:
3317:
2599:
2215:
1077:
1028:
1011:. In 2022, it was the fifteenth most commonly prescribed medication in the United States, with more than 30
934:
752:
633:
3587:"Drug use and torsades de pointes cardiac arrhythmias in Sweden: a nationwide register-based cohort study"
3382:
3345:
10560:
8953:
8229:
6815:
5965:
5898:
3670:
van Gorp F, Whyte IM, Isbister GK (September 2009). "Clinical and ECG effects of escitalopram overdose".
3244:
Clayton A, Keller A, McGarvey EL (March 2006). "Burden of phase-specific sexual dysfunction with SSRIs".
2153:"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)"
1847:
1834:
1621:
1435:, insomnia, and hypomania. Other symptoms such as panic attacks, hostility, aggressiveness, impulsivity,
713:
4011:
Lenze EJ (20 May 2009). "Escitalopram Treatment of Generalized Anxiety Disorder in Older Adults—Reply".
3312:
10936:
10921:
10881:
7948:
7460:
5728:
5636:
1943:
1935:
1775:
1473:
Excessive doses of escitalopram usually cause relatively minor untoward effects, such as agitation and
1413:
702:
3637:
3156:"Efficacy of escitalopram in the treatment of social anxiety disorder: A meta-analysis versus placebo"
2082:
states and the District of Columbia filed notices of intent to intervene as plaintiffs in the action.
10505:
10213:
7192:
6800:
6414:
5740:
4253:
Bala A, Nguyen HM, Hellstrom WJ (January 2018). "Post-SSRI Sexual Dysfunction: A Literature Review".
2943:
Cipriani A, Purgato M, Furukawa TA, Trespidi C, Imperadore G, Signoretti A, et al. (July 2012).
2516:
2152:
1024:
930:
4484:"The effect of cimetidine or omeprazole on the pharmacokinetics of escitalopram in healthy subjects"
3754:
Leth-Møller KB, Hansen AH, Torstensson M, Andersen SE, Ødum L, Gislasson G, et al. (May 2016).
10916:
5296:
1684:
1204:
729:
3869:
10956:
10941:
9426:
7063:
6370:
2669:
2099:
1976:
1085:
1036:
271:
149:
17:
5219:"Forest Laboratories, Inc. Provides Statement in Response to Complaint Filed by U.S. Government"
4229:
2755:
Cipriani A, Furukawa TA, Salanti G, Chaimani A, Atkinson LZ, Ogawa Y, et al. (April 2018).
1159:
10714:
10515:
10223:
9765:
9605:
9601:
9008:
8284:
7714:
7667:
7228:
6205:
5676:
3453:
Castro VM, Clements CC, Murphy SN, Gainer VS, Fava M, Weilburg JB, et al. (January 2013).
1081:
436:
4994:
2182:"Prescription medicines: registration of new generic medicines and biosimilar medicines, 2017"
682:
10120:
8726:
8658:
8132:
7434:
7218:
5646:
1939:
1873:
1765:
1668:
1359:
1097:
837:
482:
3026:
2808:(Plain English summary). National Institute for Health and Care Research. 1 September 2020.
2430:
622:
557:
193:
9943:
9597:
9469:
8998:
8542:
8274:
7704:
7683:
7295:
6727:
6407:
6325:
6240:
3803:Özen M, Örüm M, Kalenderoğlu A (2019). "Escitalopram-Induced Hyponatremia: A Case Report".
2897:
2835:
Solmi M, Fornaro M, Ostinelli EG, Zangani C, Croatto G, Monaco F, et al. (June 2020).
2804:"Psychiatric drugs given to children and adolescents have been ranked in order of safety".
1860:
1785:
1704:
1700:
1664:
1601:
642:
489:
5275:
5204:
3455:"QT interval and antidepressant use: a cross sectional study of electronic health records"
1223:(low sodium levels), with rates ranging from 0.5 to 32%, which can often be attributed to
8:
9283:
9128:
8993:
8721:
8578:
8404:
8269:
7924:
7699:
6151:
6091:
5146:
3900:"Cipralex 5, 10 and 20 mg film-coated tablets - Summary of Product Characteristics (SPC)"
3585:
Danielsson B, Collin J, Nyman A, Bergendal A, Borg N, State M, et al. (March 2020).
2031:
1543:
1151:
1121:
938:
548:
477:
278:
4809:"How do antidepressants work? New perspectives for refining future treatment approaches"
3756:"Antidepressants and the risk of hyponatremia: a Danish register-based population study"
3154:
Baldwin DS, Asakura S, Koyama T, Hayano T, Hagino A, Reines E, et al. (June 2016).
2901:
2736:(Plain English summary). National Institute for Health and Care Research. 3 April 2018.
2700:"Cipralex 10 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc)"
2130:
1080:, with relapse on escitalopram at 20% rather than placebo at 50%, which translates to a
756:
733:
10778:
9805:
9779:
9658:
9368:
7394:
5342:
5338:
5280:
5226:
5199:
4956:
4931:
4833:
4808:
4784:
4759:
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4692:
4668:"A comparative review of escitalopram, paroxetine, and sertraline: Are they all alike?"
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4508:
4483:
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1320:
957:
245:
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5114:
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4824:
4391:
3683:
3346:"Clinical Review: Relationship Between Antidepressant Drugs and Suicidality in Adults"
3088:
2772:
1577:
Exposure to escitalopram is increased moderately, by about 50%, when it is taken with
65:
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9359:
8097:
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7379:
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4134:
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3993:
3870:"Lexapro (escitalopram) dosing, indications, interactions, adverse effects, and more"
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3616:
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3435:
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6315:
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3808:
3775:
3767:
3726:
3718:
3679:
3606:
3598:
3528:
3520:
3474:
3466:
3427:
3390:
Overview for 13 December Meeting of Pharmacological Drugs Advisory Committee (PDAC)
3353:
Overview for 13 December Meeting of Pharmacological Drugs Advisory Committee (PDAC)
3253:
3216:
3212:
3208:
3167:
3128:
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3001:
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2768:
2737:
2637:
2524:
2387:
2333:
1947:
1711:
1609:
1209:
1192:
1116:, has been shown to affect sexual function, causing side effects such as decreased
1032:
949:
769:
582:
418:
311:
83:
4930:
O'Brien FE, O'Connor RM, Clarke G, Dinan TG, Griffin BT, Cryan JF (October 2013).
4348:
3072:
2544:
10895:
10604:
10385:
10293:
9893:
9883:
9434:
9309:
9251:
9239:
8907:
8546:
8178:
8112:
7526:
7414:
7389:
6933:
6925:
6915:
6712:
6443:
6254:
6248:
6061:
5435:
4683:
4636:
4165:
4130:
3041:
2910:
2642:
2337:
1920:
1808:
1795:
1719:
1676:
1395:
1200:
446:
426:
7256:
6434:
5323:
3771:
3602:
3071:
Slee A, Nazareth I, Bondaronek P, Liu Y, Cheng Z, Freemantle N (February 2019).
3005:
1518:, and hence may increase plasma levels of a number of CYP2D6 substrates such as
10744:
10739:
10185:
9953:
9903:
9785:
9655:
9263:
9247:
9243:
9169:
8892:
8558:
8550:
8163:
7929:
7652:
7404:
7134:
7069:
6905:
6747:
6661:
6509:
6483:
6376:
5818:
5527:
5425:
5319:
5058:"FDA OKs Generic Depression Drug – Generic Version of Lexapro Gets Green Light"
4266:
3812:
1964:
1640:
1181:
1044:
922:
5176:
4905:
4869:
4728:
4060:
3431:
3383:"Statistical Evaluation of Suicidality in Adults Treated with Antidepressants"
3257:
10905:
10629:
10405:
10175:
9928:
9888:
9519:
9303:
9299:
9269:
9235:
9209:
9199:
9154:
9118:
8978:
8922:
8761:
8701:
8623:
8603:
8586:
8564:
8485:
8480:
8430:
8394:
8254:
8193:
7919:
7439:
7424:
7384:
7014:
6899:
6876:
6694:
6656:
6635:
6266:
6213:
6001:
5873:
5848:
5843:
5783:
5758:
4775:
4032:
3820:
1688:
1680:
1648:
1495:
1419:
such as "electric shock" sensations, colloquially called "brain shivers" or "
1176:
1000:
973:
745:
393:
48:
9624:
7536:
7531:
4417:(8th ed.). Foster City, Ca: Biomedical Publications. pp. 552–553.
3132:
10819:
10804:
10784:
10759:
10195:
10088:
9938:
9830:
9745:
9720:
9454:
9349:
9339:
9164:
9159:
9003:
8973:
8861:
8609:
8521:
8490:
8445:
8440:
8435:
8279:
8249:
8137:
8046:
8006:
7909:
7829:
7719:
7709:
7521:
7516:
7501:
7496:
7475:
7232:
7201:
6984:
6974:
6964:
6943:
6866:
6809:
6651:
6473:
6311:
6299:
6209:
6116:
6046:
6036:
5888:
5878:
5778:
5773:
5696:
5691:
5671:
5656:
5610:
5336:
4965:
4913:
4877:
4842:
4793:
4736:
4701:
4610:
4517:
4460:
4356:
4310:
4274:
4173:
4138:
4103:
4095:
4068:
3997:
3855:
3789:
3740:
3691:
3620:
3542:
3488:
3439:
3265:
3230:
3181:
3140:
3096:
3049:
3013:
2978:
2929:
2870:
2790:
2399:
2345:
2245:"Lexapro- escitalopram tablet, film coated; Lexapro- escitalopram solution"
1519:
1503:
1491:
1428:
1348:
1292:
1220:
1155:
1101:
1065:
842:
306:
8814:
Selective serotonin reuptake inhibitors and serotonin receptor modulators:
4452:
4399:
4024:
1534:, etc. As escitalopram is only a weak inhibitor of CYP2D6, analgesia from
10854:
10834:
10824:
10789:
10749:
10649:
10580:
10545:
10540:
10530:
10362:
10298:
10253:
10248:
10083:
10043:
9958:
9948:
9923:
9840:
9795:
9760:
9524:
9514:
9459:
9430:
9380:
9324:
9277:
9259:
9194:
9174:
9123:
9113:
9088:
9048:
9043:
8988:
8958:
8937:
8927:
8917:
8877:
8816:
8796:
8786:
8766:
8746:
8706:
8696:
8643:
8572:
8554:
8526:
8511:
8470:
8450:
8399:
8389:
8364:
8324:
8319:
8264:
8234:
8213:
8203:
8188:
8153:
8117:
8082:
8011:
8001:
7991:
7986:
7934:
7914:
7904:
7879:
7859:
7789:
7764:
7739:
7734:
7729:
7694:
7689:
7647:
7642:
7591:
7399:
7244:
7222:
7186:
7163:
6994:
6979:
6969:
6947:
6889:
6846:
6824:
6645:
6631:
6579:
6554:
6549:
6229:
6126:
5991:
5926:
5921:
5911:
5868:
5853:
5838:
5828:
5798:
5788:
5661:
5631:
5626:
5572:
5549:
5544:
5516:
5473:
5450:
5440:
5382:
5288:
4947:
4602:
4228:(5th ed.). Arlington, VA: American Psychiatric Publishing. pp.
2741:
1696:
1590:
1547:
1523:
1474:
1462:
1172:
1147:
1136:
1048:
942:
201:
7092:
3979:
2813:
2730:"The most effective antidepressants for adults revealed in major review"
2529:
602:
10849:
10794:
10729:
10724:
10624:
10555:
10535:
10500:
10495:
10490:
10460:
10410:
10367:
10332:
10283:
10278:
10238:
10205:
10200:
10190:
10170:
10165:
10098:
10073:
9898:
9845:
9835:
9800:
9769:
9755:
9730:
9725:
9705:
9700:
9573:
9529:
9494:
9421:
9384:
9344:
9314:
9291:
9255:
9204:
9189:
9073:
9058:
9028:
9018:
9013:
8968:
8963:
8902:
8897:
8882:
8856:
8826:
8821:
8806:
8801:
8776:
8771:
8741:
8736:
8716:
8711:
8635:
8614:
8597:
8592:
8475:
8465:
8349:
8334:
8304:
8294:
8289:
8244:
8239:
8173:
8168:
8127:
8107:
8092:
8067:
8051:
8026:
8021:
7899:
7889:
7874:
7819:
7809:
7799:
7779:
7769:
7754:
7749:
7672:
7662:
7657:
7470:
7363:
7358:
7240:
7236:
7171:
7167:
7159:
7151:
7009:
6937:
6884:
6861:
6856:
6839:
6779:
6737:
6722:
6604:
6559:
6544:
6524:
6519:
6514:
6430:
6347:
6333:
6319:
6225:
6221:
6217:
6171:
6141:
6136:
6131:
6111:
6081:
6071:
6031:
6016:
5996:
5883:
5863:
5833:
5813:
5793:
5753:
5701:
5686:
5681:
5641:
5605:
5577:
5506:
5483:
5478:
5430:
5402:
5397:
5392:
5377:
5367:
4287:
4151:
3722:
3524:
2035:
1999:
1992:
1727:
1707:
1692:
1586:
1582:
1578:
1551:
1502:. Chiral techniques are available to distinguish escitalopram from its
1482:
1478:
1420:
1412:
Escitalopram discontinuation, particularly abruptly, may cause certain
1286:
1276:
1271:
1213:
1164:
1143:
1125:
1004:
985:
981:
961:
845:
802:
613:
471:
285:
39:
31:
3847:
2852:
10829:
10814:
10799:
10774:
10704:
10619:
10599:
10550:
10485:
10480:
10395:
10263:
10160:
10140:
10113:
10093:
10018:
9918:
9908:
9878:
9820:
9815:
9695:
9690:
9561:
9509:
9479:
9474:
9394:
9376:
9372:
9329:
9287:
9230:
9179:
9098:
9068:
8932:
8851:
8841:
8836:
8831:
8756:
8751:
8631:
8627:
8516:
8506:
8455:
8374:
8344:
8208:
8158:
8077:
8072:
8041:
8036:
7996:
7894:
7884:
7849:
7774:
7744:
7677:
7637:
7601:
7506:
7491:
7465:
7429:
7419:
7348:
7343:
7338:
7333:
7044:
7039:
7034:
7024:
7004:
6929:
6851:
6794:
6684:
6666:
6641:
6614:
6599:
6594:
6589:
6584:
6529:
6463:
6399:
6235:
6121:
6056:
6051:
6026:
6021:
6011:
6006:
5916:
5858:
5823:
5803:
5768:
5724:
5582:
5539:
5511:
5445:
5387:
3834:
Naschitz JE (June 2018). "Escitalopram Dose-Dependent Hyponatremia".
3470:
1972:
1968:
1912:
1731:
1723:
1656:
1632:
1627:
Escitalopram, similarly to other SSRIs, may increase bleed risk with
1613:
1594:
1449:
1436:
1424:
1364:
1330:
1315:
1310:
1305:
969:
568:
502:
187:
7178:
6786:
6771:
5560:
5413:
3753:
1931:, which may contribute to a reduction in negative affective biases.
1911:
Escitalopram increases intrasynaptic levels of the neurotransmitter
10809:
10764:
10654:
10614:
10609:
10525:
10372:
10233:
9865:
9860:
9850:
9548:
9499:
9489:
9388:
9334:
9295:
9273:
9063:
9053:
8846:
8639:
8582:
8568:
8339:
8329:
8031:
8016:
7981:
7839:
7834:
7824:
7794:
7596:
7353:
7019:
6999:
6919:
6732:
6676:
6619:
6609:
6574:
6564:
6539:
6468:
5986:
5942:
5666:
5651:
5494:
3197:"Selective serotonin reuptake inhibitors for premenstrual syndrome"
2027:
2019:
1996:
1916:
1636:
1535:
1527:
1300:
989:
662:
593:
229:
4929:
4890:
1554:
by 50% and overall exposure by 82%. Escitalopram does not inhibit
825:
10455:
10435:
10430:
10337:
10273:
10038:
10013:
10008:
10003:
9998:
9993:
9988:
9933:
9750:
9715:
9354:
9184:
9137:
9133:
9083:
9078:
9033:
9023:
8983:
8912:
8791:
8460:
8413:
8409:
8359:
8354:
8309:
8299:
8259:
8183:
8102:
7864:
7854:
7844:
7814:
7759:
7581:
7576:
7571:
7566:
7561:
7556:
7551:
7511:
7409:
7328:
6989:
6626:
6455:
5808:
3194:
2487:"Protocol for switching patients from escitalopram to citalopram"
1620:. As an SSRI, escitalopram should not be given concurrently with
1605:
1567:
1531:
1416:
1342:
1325:
1281:
1185:
1163:
prolongation than a therapeutically equivalent 60 mg/day dose of
968:
in people up to the age of 24 years. It is unclear if use during
455:
35:
5115:"Forest Laboratories Receives Patent Term Extension for Lexapro"
4437:
4223:
2575:"Escitalopram Drug Usage Statistics, United States, 2013 - 2022"
10440:
10425:
10342:
10303:
10268:
10145:
10063:
10058:
10023:
9983:
9685:
9364:
9093:
9038:
8781:
8619:
8369:
8314:
8122:
7869:
7546:
7143:
7029:
6756:
5532:
Tooltip Noradrenergic and specific serotonergic antidepressants
5355:
2945:"Citalopram versus other anti-depressive agents for depression"
2942:
2754:
2378:
Rao N (2007). "The clinical pharmacokinetics of escitalopram".
1934:
Of the SSRIs currently available, escitalopram has the highest
1821:
1571:
1563:
1559:
1555:
1515:
1486:
1370:
1336:
1266:
1219:
Like other SSRIs, escitalopram has also been reported to cause
1117:
953:
693:
539:)-1--1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
463:
459:
56:
1003:
in 2002. Escitalopram is rarely replaced by twice the dose of
10400:
10327:
9978:
9680:
5723:
4529:
4527:
1354:
1051:. In Australia it is approved for major depressive disorder.
816:
673:
511:
507:
451:
4589:
Boyer EW, Shannon M (March 2005). "The serotonin syndrome".
4045:
2834:
1616:, tramadol, and other serotonergic drugs due to the risk of
1538:
may not be affected. Escitalopram (at the maximum dose of 20
718:
10377:
9870:
9438:
5593:
2014:
1896:
1378:
1146:
and escitalopram are associated with a mild dose-dependent
1131:
There is also evidence that SSRIs may cause an increase in
653:
110:
95:
89:
7960:
5461:
4524:
3452:
3195:
Marjoribanks J, Brown J, O'Brien PM, Wyatt K (June 2013).
3153:
2883:
6708:
3070:
2515:
2160:
1423:" by those affected. Frequent symptoms in one study were
1196:
1007:; escitalopram is safer and more effective. It is on the
122:
104:
9409:
2269:
9736:
4760:"Serotonin and brain function: a tale of two receptors"
4665:
3930:"Escitalopram-Lupin Tablets (LUPIN AUSTRALIA PTY. LTD)"
1009:
World Health Organization's List of Essential Medicines
8951:
Serotonin–norepinephrine–dopamine reuptake inhibitors:
8227:
Serotonin–norepinephrine–dopamine reuptake inhibitors:
6496:
1096:
Escitalopram is effective in reducing the symptoms of
10879:
10378:
9871:
8670:
7124:
5117:(Press release). PRNewswire-FirstCall. 2 March 2006.
4481:
4380:
Journal of Chromatography. B, Biomedical Applications
4226:
Diagnostic and Statistical Manual of Mental Disorders
4081:
3669:
3243:
2433:. The American Society of Health-System Pharmacists.
1600:
Escitalopram should be taken with caution when using
113:
92:
86:
7307:
7183:
Tooltip Serotonin-norepinephrine reuptake inhibitors
6831:
6791:
Tooltip Serotonin antagonist and reuptake inhibitors
6776:
Tooltip Serotonin-norepinephrine reuptake inhibitors
5565:
Tooltip Serotonin antagonist and reuptake inhibitors
5418:
Tooltip Serotonin–norepinephrine reuptake inhibitors
4894:
The International Journal of Neuropsychopharmacology
4855:
3802:
3704:
2319:
2317:
2315:
2313:
2311:
2309:
2307:
2305:
2303:
1199:
measurements should be considered for patients with
1084:
of 3.33. Escitalopram appears effective in treating
119:
116:
107:
101:
10561:
6816:
5899:
5499:
Tooltip Norepinephrine–dopamine reuptake inhibitors
5173:
US District Court for the district of Massachusetts
5142:"Forest Laboratories: A Tale of Two Whistleblowers"
4482:Malling D, Poulsen MN, Søgaard B (September 2005).
4252:
3642:
Medicines and Healthcare products Regulatory Agency
3552:
2239:
2237:
2145:
2076:
1023:Escitalopram has FDA approval for the treatment of
929:(SSRI) class. Escitalopram is mainly used to treat
125:
98:
7949:
5276:"A Peek at How Forest Laboratories Pushed Lexapro"
4757:
4337:Expert Opinion on Drug Metabolism & Toxicology
2670:"Lundbeck's Cipralex gets EU ok for OCD treatment"
2026:Escitalopram was developed in cooperation between
10506:
10214:
7286:
7193:
6801:
5741:
5166:"United States of America v. Forest Laboratories"
4666:Sanchez C, Reines EH, Montgomery SA (July 2014).
4535:"Drug interactions between bupropion and Lexapro"
2300:
1235:Very common effects (>10% incidence) include:
1076:Escitalopram appears to be effective in treating
999:Escitalopram was approved for medical use in the
10903:
5964:
4806:
2279:List of nationally authorised medicinal products
2234:
1167:, which increased the QTc interval by 18.5 ms.
581:
178:(+)-Citalopram; (+)-Citalopram; LU-26054; MLD-55
7148:Tooltip Selective serotonin reuptake inhibitors
6761:Tooltip Selective serotonin reuptake inhibitors
6301:
5360:Tooltip Selective serotonin reuptake inhibitors
4415:Disposition of toxic drugs and chemicals in man
3665:
3663:
3380:
556:
10516:
10224:
4717:Naunyn-Schmiedeberg's Archives of Pharmacology
4714:
3705:Hasnain M, Howland RH, Vieweg WV (July 2013).
3580:
3578:
2323:
9654:
9640:
8875:Serotonin–norepinephrine reuptake inhibitors:
8659:
8151:Serotonin–norepinephrine reuptake inhibitors:
7979:Selective norepinephrine reuptake inhibitors:
7272:
7108:
6415:
5304:
4758:Carhart-Harris RL, Nutt DJ (September 2017).
3939:. Lupin Australia Pty Ltd. 21 December 2011.
3117:
2884:Ramsberg J, Asseburg C, Henriksson M (2012).
2457:"Escitalopram (Lexapro) Use During Pregnancy"
8065:Norepinephrine–dopamine reuptake inhibitors:
7296:
4972:
4659:
4588:
4475:
4110:
3974:(5). Thomas Land Publishers, Inc.: 358–361.
3660:
3446:
3417:
3411:
3237:
3188:
3147:
3111:
2985:
1967:and hence P-glycoprotein inhibitors such as
1663:due to escitalopram's inhibitory effects on
233:
6701:
6335:
6152:
6092:
5598:Tooltip Serotonin modulator and stimulators
4406:
4371:
4330:
4328:
4116:
4084:Aviation, Space, and Environmental Medicine
3575:
3502:
3500:
3498:
3310:
3201:The Cochrane Database of Systematic Reviews
2949:The Cochrane Database of Systematic Reviews
2270:Human Medicines Division (September 2022).
1401:
1255:
410:In general: ℞ (Prescription only)
9647:
9633:
7965:Tooltip Norepinephrine reuptake inhibitors
7279:
7265:
7115:
7101:
6422:
6408:
5466:Tooltip Norepinephrine reuptake inhibitors
5318:
5311:
5297:
5192:
5019:
4983:(6 ed.). Elsevier. 2016. p. 383.
4807:Harmer CJ, Duman RS, Cowen PJ (May 2017).
3381:Levenson M, Holland C (17 November 2006).
3343:
2604:Australian Institute of Health and Welfare
2425:
2423:
2421:
2419:
2417:
2415:
2413:
2411:
2409:
2117:
2115:
1431:, agitation, anxiety, headache, lethargy,
1260:Common effects (1–10% incidence) include:
755:
732:
621:
7122:
4955:
4832:
4783:
4691:
4672:International Clinical Psychopharmacology
4507:
4412:
4224:American Psychiatric Association (2013).
3987:
3779:
3730:
3610:
3532:
3478:
3220:
3171:
2968:
2919:
2909:
2860:
2780:
2641:
2528:
2373:
2371:
2369:
2367:
2365:
2363:
2361:
2359:
2357:
2355:
641:
9414:Tooltip Vesicular monoamine transporters
8689:Selective serotonin reuptake inhibitors:
6193:
4488:British Journal of Clinical Pharmacology
4325:
3833:
3711:Journal of Psychiatry & Neuroscience
3513:Journal of Psychiatry & Neuroscience
3495:
2013:
964:. More serious side effects may include
10952:Selective serotonin reuptake inhibitors
9776:Dehydroepiandrosterone sulfate (DHEA-S)
9741:Tooltip Calcitonin gene-related peptide
6444:
5139:
5086:
5027:"Mozarin, zamienniki i podobne rodukty"
4334:
3961:
3344:Stone MB, Jones ML (17 November 2006).
2509:
2479:
2406:
2112:
1950:of SERT, escitalopram also binds to an
1100:, whether taken continuously or in the
728:
601:
206:
14:
10904:
6501:Tooltip positive allosteric modulators
6484:
6429:
5273:
5007:from the original on 27 September 2007
4925:
4923:
4441:Clinical Pharmacology and Therapeutics
4219:
4217:
4119:Journal of Clinical Psychopharmacology
3558:
3509:"Antidepressants and QTc prolongation"
3325:from the original on 27 September 2007
2352:
2206:
2186:Therapeutic Goods Administration (TGA)
2041:
1742:
1385:
1230:
927:selective serotonin reuptake inhibitor
863:Fc1ccc(cc1)3(OCc2cc(C#N)ccc23)CCCN(C)C
746:
402:
374:
291:Selective serotonin reuptake inhibitor
9628:
8675:Tooltip Serotonin reuptake inhibitors
7260:
7096:
6403:
6288:
6192:
5963:
5722:
5335:
5292:
5251:from the original on 30 November 2020
5193:Meier B, Carey B (25 February 2009).
4622:
4620:
4563:
4377:
4010:
3632:
3630:
2991:
2523:. Geneva: World Health Organization.
2467:from the original on 31 December 2017
2437:from the original on 29 December 2017
2288:from the original on 6 September 2022
2002:, which is responsible for its name:
1442:
701:
681:
387:
224:
192:
7312:Tooltip Dopamine reuptake inhibitors
6836:Tooltip Monoamine oxidase inhibitors
5095:from the original on 30 October 2021
4566:2006 Lippincott's Nursing Drug Guide
3910:from the original on 3 December 2013
3880:from the original on 2 December 2013
3374:
3337:
3030:Current Medical Research and Opinion
1071:
310:
10566:Tooltip 3,4,5-Trimethoxyamphetamine
6821:Tooltip Tetracyclic antidepressants
5904:Tooltip Tetracyclic antidepressants
5068:from the original on 5 January 2007
5055:
4920:
4591:The New England Journal of Medicine
4214:
3922:
3892:
3862:
3707:"Escitalopram and QTc prolongation"
3506:
3304:
3292:from the original on 15 August 2018
2555:from the original on 30 August 2024
2497:from the original on 10 August 2020
2377:
2272:"Active substance(s): escitalopram"
1958:
1542:mg/day) has been found to increase
661:
572:
34:version of the medication. For its
24:
9009:Didesmethylsibutramine (BTS-54505)
8285:Didesmethylsibutramine (BTS-54505)
7954:Tooltip Norepinephrine transporter
7715:Didesmethylsibutramine (BTS-54505)
5225:. 26 February 2009. Archived from
5121:from the original on 15 April 2009
4708:
4647:from the original on 9 August 2022
4617:
4545:from the original on 23 April 2018
4004:
3943:from the original on 29 March 2019
3805:Psychiatry and Behavioral Sciences
3627:
3399:from the original on 16 March 2007
3362:from the original on 16 March 2007
3121:The Journal of Clinical Psychiatry
2222:from the original on 3 August 2023
2038:, which has similar pharmacology.
25:
10968:
10740:Chlorphenamine (chlorpheniramine)
10511:Tooltip N,N-Diisopropyltryptamine
10219:Tooltip N,N-Diisopropyltryptamine
7527:Etybenzatropine (ethybenztropine)
7198:Tooltip Tricyclic antidepressants
6806:Tooltip Tricyclic antidepressants
6289:
5746:Tooltip Tricyclic antidepressants
5267:
5089:"US court upholds Lexapro patent"
4995:"2000 Annual Report. p 28 and 33"
3684:10.1016/j.annemergmed.2009.04.016
3648:from the original on 6 March 2013
3280:"Lexapro prescribing information"
2710:from the original on 10 June 2020
2680:from the original on 10 June 2020
2650:from the original on 10 June 2020
1929:brain-derived neurotrophic factor
337:
256:
10889:
8999:Desmethylsibutramine (BTS-54354)
8275:Desmethylsibutramine (BTS-54354)
7705:Desmethylsibutramine (BTS-54354)
5195:"Drug Maker Is Accused of Fraud"
4500:10.1111/j.1365-2125.2005.02423.x
3836:Journal of Clinical Pharmacology
3584:
3160:European Neuropsychopharmacology
2600:"Medicines in the health system"
2392:10.2165/00003088-200746040-00002
2077:Allegations of illegal marketing
1718:(except palonosetron), and some
1498:is generally accomplished using
789:
786:
780:
82:
64:
55:
9610:Monoamine metabolism modulators
5233:
5211:
5186:
5158:
5133:
5107:
5080:
5049:
4987:
4979:"Citalopram and escitalopram".
4884:
4849:
4800:
4751:
4629:
4582:
4557:
4431:
4303:10.1001/jamapsychiatry.2013.684
4281:
4246:
4188:
4145:
4075:
4039:
3955:
3904:electronic Medicines Compendium
3827:
3796:
3747:
3698:
3272:
3173:10.1016/j.euroneuro.2016.02.013
3064:
3020:
2936:
2877:
2828:
2797:
2748:
2722:
2692:
2662:
2618:
2592:
2567:
2537:
2449:
2067:U.S. District Court of Delaware
2055:
1963:Escitalopram is a substrate of
1737:
1509:
1297:Decreased or increased appetite
1107:
1027:in adolescents and adults, and
1018:
941:, available commercially as an
888:Key:WSEQXVZVJXJVFP-FQEVSTJZSA-N
10521:Tooltip N,N-Dipropyltryptamine
10229:Tooltip N,N-Dipropyltryptamine
9929:Pentoxyverine (carbetapentane)
5140:Frankel A (27 February 2009).
4981:Meyler's Side Effects of Drugs
4049:Journal of Affective Disorders
3246:Journal of Affective Disorders
3213:10.1002/14651858.CD001396.pub3
2961:10.1002/14651858.CD006534.pub2
2326:Expert Opin Drug Metab Toxicol
2263:
2200:
2174:
2046:
976:is safe. Escitalopram is the (
795:
774:
363:
350:
13:
1:
10870:Receptor/signaling modulators
9766:Dehydroepiandrosterone (DHEA)
9590:Receptor/signaling modulators
8664:Tooltip Serotonin transporter
7288:Monoamine reuptake inhibitors
5274:Harris G (1 September 2009).
4825:10.1016/S2215-0366(17)30015-9
4764:Journal of Psychopharmacology
4392:10.1016/s0378-4347(96)00177-6
4349:10.1517/17425255.2015.1063614
3420:Annals of Clinical Psychiatry
3089:10.1016/S0140-6736(18)31793-8
2773:10.1016/S0140-6736(17)32802-7
2281:. European Medicines Agency.
2105:
1995:(left-handed version) of the
1514:Escitalopram weakly inhibits
1408:SSRI discontinuation syndrome
1054:
1041:obsessive–compulsive disorder
913:, sold under the brand names
359:(Other controlled substances)
8504:Tetracyclic antidepressants:
7301:Tooltip Dopamine transporter
5966:Monoamine oxidase inhibitors
4684:10.1097/YIC.0000000000000023
4166:10.1097/WNF.0000000000000139
4131:10.1097/JCP.0b013e3181727534
3672:Annals of Emergency Medicine
3318:Food and Drug Administration
3042:10.1185/03007995.2010.529430
2911:10.1371/journal.pone.0042003
2643:10.18773/austprescr.2003.107
2338:10.1517/17425255.2014.863873
1982:
1455:
1245:Ejaculation disorder (9–14%)
1078:generalized anxiety disorder
1033:generalized anxiety disorder
1029:generalized anxiety disorder
948:Common side effects include
935:generalized anxiety disorder
7:
9954:Racemethorphan (methorphan)
8954:3,3-Diphenylcyclobutanamine
8230:3,3-Diphenylcyclobutanamine
6160:Tooltip Monoamine oxidase B
6100:Tooltip Monoamine oxidase A
5729:tetracyclic antidepressants
5087:Laforte ME (14 July 2006).
5033:(in Polish). Archived from
3772:10.1136/bmjopen-2016-011200
3603:10.1136/bmjopen-2019-034560
3559:US FDA (15 December 2017).
3006:10.1016/j.encep.2011.11.003
2093:
1468:
10:
10973:
9594:Monoamine releasing agents
9152:Tricyclic antidepressants:
8428:Tricyclic antidepressants:
7497:Benzatropine (benztropine)
5637:Dextromethorphan/bupropion
4267:10.1016/j.sxmr.2017.07.002
4154:Clinical Neuropharmacology
3813:10.5455/pbs.20171230091731
2533:. WHO/MHP/HPS/EML/2023.02.
2218:(published 4 April 2023).
2009:
1944:norepinephrine transporter
1405:
1345:(muscular aches and pains)
764:Chemical and physical data
510:(major; 8–10% unchanged),
30:This article is about the
29:
10932:Drugs developed by AbbVie
10863:
10589:
10312:
9665:
9582:
9538:
9407:
9218:
9147:
8946:
8870:
8684:
8657:
8535:
8499:
8423:
8222:
8146:
8060:
7974:
7947:
7630:
7484:
7448:
7372:
7321:
7294:
7211:
7133:
7053:
6957:
6898:
6875:
6746:
6693:
6675:
6482:
6442:
6360:
6295:
6284:
6201:
6188:
6150:
6090:
5976:
5972:
5959:
5935:
5897:
5739:
5735:
5718:
5619:
5591:
5558:
5525:
5492:
5459:
5411:
5353:
5349:
5331:
4906:10.1017/S1461145705006462
4870:10.1007/s00213-011-2463-5
4729:10.1007/s00210-013-0911-y
4061:10.1016/j.jad.2011.04.047
3432:10.1080/10401230601163550
3258:10.1016/j.jad.2005.12.007
2517:World Health Organization
1685:tricyclic antidepressants
1351:(abnormal skin sensation)
1112:Escitalopram, like other
1025:major depressive disorder
931:major depressive disorder
896:
871:
851:
836:
814:
801:
768:
763:
744:
712:
692:
672:
652:
632:
612:
592:
567:
547:
523:
518:
501:
488:
470:
445:
435:
425:
417:
327:
322:
297:
284:
270:
244:
214:
200:
182:
158:
154:Cipralex, Lexapro, others
148:
77:
72:
63:
54:
10912:4-Fluorophenyl compounds
9831:Fabomotizole (afobazole)
9806:Dimethyltryptamine (DMT)
8878:Atomoxetine (tomoxetine)
8154:Atomoxetine (tomoxetine)
6343:Rubidium chloride (RbCl)
4776:10.1177/0269881117725915
3392:. FDA. pp. 75–140.
1546:of the CYP2D6 substrate
1402:Discontinuation symptoms
1256:Common (1–10% incidence)
1205:electrolyte disturbances
1091:
1064:which led to charges of
10927:Dimethylamino compounds
10795:Mepyramine (pyrilamine)
10476:3-Methoxydextrallorphan
10136:3-Methoxydextrallorphan
9959:Racemorphan (morphanol)
9256:mepyramine (pyrilamine)
7229:Atypical antipsychotics
6453:Tooltip 5-HT1A receptor
6206:Atypical antipsychotics
4936:Neuropsychopharmacology
4255:Sexual Medicine Reviews
3962:Mancano MA (May 2016).
3355:. FDA. pp. 11–74.
3311:Levenson M, Holland C.
3133:10.4088/JCP.08m04749blu
2216:Diário Oficial da União
2127:Drugs.com International
2100:List of antidepressants
1942:(SERT) compared to the
1500:chromatographic methods
1086:social anxiety disorder
1037:social anxiety disorder
10850:Tiospirone (BMY-13859)
10790:Gevotroline (WY-47384)
10715:18-Methoxycoronaridine
10702:Allosteric modulators:
10461:Panamesine (EMD-57455)
10411:Siramesine (Lu 28-179)
10348:Ditolylguanidine (DTG)
10111:Allosteric modulators:
10074:Panamesine (EMD-57455)
10019:BMY-14802 (BMS-181100)
9811:Ditolylguanidine (DTG)
9791:Dextromethorphan (DXM)
9530:Vanoxerine (GBR-12909)
9377:pethidine (meperidine)
8632:pethidine (meperidine)
7420:Pethidine (meperidine)
7219:Typical antipsychotics
6493:Tooltip GABAA receptor
4813:The Lancet. Psychiatry
4096:10.3357/asem.1879.2006
3937:TGA eBusiness Services
2626:"Escitalopram oxalate"
2023:
1669:serotonin transporters
1610:dextromethorphan (DXM)
1333:(erectile dysfunction)
1184:drug in the study was
1082:number needed to treat
921:, among others, is an
10121:Methylphenylpiracetam
9696:Alazocine (SKF-10047)
9614:Monoamine neurotoxins
9180:Dosulepin (dothiepin)
8727:Didesmethylcitalopram
8456:Dosulepin (dothiepin)
8133:Serdexmethylphenidate
7435:Serdexmethylphenidate
5247:. 15 September 2010.
4453:10.1038/clpt.2009.154
4025:10.1001/jama.2009.652
3507:Lam RW (March 2013).
2630:Australian Prescriber
2545:"The Top 300 of 2022"
2017:
1987:Escitalopram is the (
1940:serotonin transporter
1098:premenstrual syndrome
483:Didesmethylcitalopram
9944:Pregnenolone sulfate
9756:Cutamesine (SA-4503)
9505:Methoxytetrabenazine
9470:Dihydrotetrabenazine
9284:Arylcyclohexylamines
8579:Arylcyclohexylamines
7730:Dizocilpine (MK-801)
7684:Chaenomeles speciosa
7385:Benocyclidine (BTCP)
6728:Gabapentin enacarbil
6327:Hypericum perforatum
6195:Adjunctive therapies
5223:Forest press-release
5207:on 11 November 2020.
5154:on 28 February 2009.
4948:10.1038/npp.2013.120
4603:10.1056/NEJMra041867
2767:(10128): 1357–1366.
2742:10.3310/signal-00580
2704:www.medicines.org.uk
2065:. In July 2006, the
1716:receptor antagonists
1665:platelet aggregation
10094:Rimcazole (BW-234U)
9129:Threohydrobupropion
8994:Desmethylsertraline
8722:Desmethylcitalopram
8405:Threohydrobupropion
8270:Desmethylsertraline
7925:Threohydrobupropion
7700:Desmethylsertraline
5343:receptor modulators
5339:reuptake inhibitors
5229:on 24 January 2013.
5147:The American Lawyer
3980:10.1310/hpj5105-358
2902:2012PLoSO...742003R
2814:10.3310/alert_40795
2676:. 12 January 2007.
2042:Society and culture
2032:Forest Laboratories
1977:blood brain barrier
1749:
1743:Mechanism of action
1653:omega-3 fatty acids
1386:Psychomotor effects
1231:Very common effects
1152:torsades de pointes
1122:delayed ejaculation
988:(which exists as a
478:Desmethylcitalopram
383:(Prescription only)
346:(Prescription only)
51:
27:SSRI antidepressant
9851:Igmesine (JO-1784)
9780:prasterone sulfate
9369:dextropropoxyphene
7395:Dexmethylphenidate
7080:Never to phase III
6387:Never to phase III
5281:The New York Times
5200:The New York Times
5037:on 17 October 2020
5000:. Lundbeck. 2000.
4858:Psychopharmacology
4413:Baselt RC (2008).
3906:. 2 October 2013.
3723:10.1503/jpn.130055
3525:10.1503/jpn.120256
3083:(10173): 768–777.
2380:Clin Pharmacokinet
2251:. 17 November 2023
2024:
1747:
1645:antiplatelet drugs
1618:serotonin syndrome
1443:Sexual dysfunction
1433:emotional lability
1398:task performance.
1367:(nasal congestion)
1321:Excessive sweating
1248:Somnolence (4–13%)
992:), hence the name
945:salt exclusively.
47:
10937:Enantiopure drugs
10922:CYP2D6 inhibitors
10877:
10876:
10712:Unknown/unsorted:
10473:Unknown/unsorted:
10208:
10133:Unknown/unsorted:
9796:Dextrorphan (DXO)
9622:
9621:
9617:
9403:
9402:
8678:
8653:
8652:
8098:Levophacetoperane
7968:
7943:
7942:
7805:Levophacetoperane
7380:4-Fluoropethidine
7315:
7254:
7253:
7127:pharmacotherapies
7090:
7089:
6662:Ethanol (alcohol)
6570:Ethyl loflazepate
6397:
6396:
6356:
6355:
6329:(St. John's Wort)
6280:
6279:
6245:lithium carbonate
6184:
6183:
6180:
6179:
5955:
5954:
5951:
5950:
5764:Amitriptylinoxide
5714:
5713:
5710:
5709:
5182:on 11 March 2009.
4942:(11): 2209–2219.
4597:(11): 1112–1120.
4575:978-1-58255-436-5
4343:(10): 1585–1597.
4090:(12): 1256–1265.
3968:Hospital Pharmacy
3848:10.1002/jcph.1091
3644:. December 2011.
3036:(12): 2757–2764.
2853:10.1002/wps.20765
2636:: 146–151. 2003.
2210:(31 March 2023).
1909:
1908:
1133:suicidal ideation
1072:Anxiety disorders
966:suicidal thoughts
908:
907:
827:Interactive image
714:CompTox Dashboard
406:
391:
378:
366:
354:
341:
260:
227:
174:-(+)-Citalopram;
16:(Redirected from
10964:
10894:
10893:
10892:
10885:
10567:
10563:
10522:
10518:
10512:
10508:
10381:(midomafetamine)
10380:
10230:
10226:
10220:
10216:
10206:
9874:(midomafetamine)
9873:
9742:
9738:
9649:
9642:
9635:
9626:
9625:
9584:
9571:Antagonist-like:
9465:Deutetrabenazine
9415:
9411:
9355:MIN-117 (WF-516)
9320:Dextromethorphan
8692:6-Nitroquipazine
8682:
8681:
8676:
8672:
8667:
8665:
8661:
8088:Hydroxybupropion
7972:
7971:
7966:
7962:
7957:
7955:
7951:
7845:MIN-117 (WF-516)
7785:Hydroxybupropion
7725:Diphenylpyraline
7456:Diphenylprolinol
7319:
7318:
7313:
7309:
7304:
7302:
7298:
7281:
7274:
7267:
7258:
7257:
7199:
7195:
7184:
7180:
7149:
7145:
7126:
7117:
7110:
7103:
7094:
7093:
6926:Alpha-2 agonists
6916:Alpha-1 blockers
6909:
6837:
6833:
6822:
6818:
6807:
6803:
6792:
6788:
6777:
6773:
6762:
6758:
6716:
6710:
6707:
6535:Chlordiazepoxide
6502:
6498:
6494:
6490:
6454:
6450:
6424:
6417:
6410:
6401:
6400:
6337:
6303:
6286:
6285:
6259:triiodothyronine
6255:Thyroid hormones
6190:
6189:
6161:
6157:
6101:
6097:
6042:Phenoxypropazine
5974:
5973:
5961:
5960:
5905:
5901:
5747:
5743:
5737:
5736:
5720:
5719:
5599:
5595:
5566:
5562:
5533:
5529:
5500:
5496:
5467:
5463:
5419:
5415:
5361:
5357:
5351:
5350:
5333:
5332:
5313:
5306:
5299:
5290:
5289:
5285:
5261:
5260:
5258:
5256:
5237:
5231:
5230:
5215:
5209:
5208:
5203:. Archived from
5190:
5184:
5183:
5181:
5175:. Archived from
5170:
5162:
5156:
5155:
5150:. Archived from
5137:
5131:
5130:
5128:
5126:
5111:
5105:
5104:
5102:
5100:
5084:
5078:
5077:
5075:
5073:
5053:
5047:
5046:
5044:
5042:
5023:
5017:
5016:
5014:
5012:
5006:
4999:
4991:
4985:
4984:
4976:
4970:
4969:
4959:
4927:
4918:
4917:
4888:
4882:
4881:
4853:
4847:
4846:
4836:
4804:
4798:
4797:
4787:
4770:(9): 1091–1120.
4755:
4749:
4748:
4712:
4706:
4705:
4695:
4663:
4657:
4656:
4654:
4652:
4641:www.uptodate.com
4633:
4627:
4624:
4615:
4614:
4586:
4580:
4579:
4564:Karch A (2006).
4561:
4555:
4554:
4552:
4550:
4531:
4522:
4521:
4511:
4479:
4473:
4472:
4435:
4429:
4428:
4410:
4404:
4403:
4375:
4369:
4368:
4332:
4323:
4322:
4285:
4279:
4278:
4250:
4244:
4243:
4221:
4212:
4211:
4209:
4207:
4198:. Archived from
4192:
4186:
4185:
4149:
4143:
4142:
4114:
4108:
4107:
4079:
4073:
4072:
4055:(1–3): 421–426.
4043:
4037:
4036:
4008:
4002:
4001:
3991:
3959:
3953:
3952:
3950:
3948:
3934:
3926:
3920:
3919:
3917:
3915:
3896:
3890:
3889:
3887:
3885:
3866:
3860:
3859:
3831:
3825:
3824:
3800:
3794:
3793:
3783:
3751:
3745:
3744:
3734:
3702:
3696:
3695:
3667:
3658:
3657:
3655:
3653:
3634:
3625:
3624:
3614:
3582:
3573:
3572:
3570:
3568:
3556:
3550:
3549:
3536:
3504:
3493:
3492:
3482:
3471:10.1136/bmj.f288
3450:
3444:
3443:
3415:
3409:
3408:
3406:
3404:
3398:
3387:
3378:
3372:
3371:
3369:
3367:
3361:
3350:
3341:
3335:
3334:
3332:
3330:
3308:
3302:
3301:
3299:
3297:
3291:
3284:
3276:
3270:
3269:
3241:
3235:
3234:
3224:
3192:
3186:
3185:
3175:
3166:(6): 1062–1069.
3151:
3145:
3144:
3115:
3109:
3108:
3068:
3062:
3061:
3024:
3018:
3017:
2989:
2983:
2982:
2972:
2940:
2934:
2933:
2923:
2913:
2881:
2875:
2874:
2864:
2841:World Psychiatry
2832:
2826:
2825:
2801:
2795:
2794:
2784:
2752:
2746:
2745:
2726:
2720:
2719:
2717:
2715:
2696:
2690:
2689:
2687:
2685:
2666:
2660:
2659:
2657:
2655:
2645:
2622:
2616:
2615:
2613:
2611:
2596:
2590:
2589:
2587:
2585:
2571:
2565:
2564:
2562:
2560:
2541:
2535:
2534:
2532:
2513:
2507:
2506:
2504:
2502:
2483:
2477:
2476:
2474:
2472:
2453:
2447:
2446:
2444:
2442:
2427:
2404:
2403:
2375:
2350:
2349:
2321:
2298:
2297:
2295:
2293:
2287:
2276:
2267:
2261:
2260:
2258:
2256:
2241:
2232:
2231:
2229:
2227:
2204:
2198:
2197:
2195:
2193:
2178:
2172:
2171:
2169:
2167:
2157:nctr-crs.fda.gov
2149:
2143:
2142:
2140:
2138:
2129:. Archived from
2119:
1975:may improve its
1959:Pharmacokinetics
1948:orthosteric site
1915:by blocking the
1750:
1748:Binding profile
1746:
1541:
1251:Insomnia (7–12%)
1210:liver impairment
1193:long QT syndrome
1160:positive control
1047:with or without
1014:
950:trouble sleeping
904:
903:
829:
809:
797:
791:
788:
782:
776:
759:
748:
737:
736:
722:
720:
705:
685:
665:
645:
625:
605:
585:
575:
574:
560:
493:
404:
401:
396:
389:
386:
376:
373:
365:
362:
352:
349:
339:
336:
314:
258:
255:
237:
226:
223:
210:
196:
143:
142:
141:
139:
132:
131:
128:
127:
124:
121:
118:
115:
112:
109:
106:
103:
100:
97:
94:
91:
88:
68:
59:
52:
50:
46:
21:
10972:
10971:
10967:
10966:
10965:
10963:
10962:
10961:
10917:Antidepressants
10902:
10901:
10900:
10890:
10888:
10880:
10878:
10873:
10859:
10779:St. John's wort
10605:Ethylketazocine
10585:
10565:
10520:
10510:
10386:Methamphetamine
10317:
10308:
10294:Trifluoperazine
10228:
10218:
9894:Methylphenidate
9884:Methamphetamine
9740:
9670:
9661:
9653:
9623:
9618:
9578:
9556:DAT modulators:
9534:
9435:methamphetamine
9413:
9399:
9310:Cyclobenzaprine
9252:diphenhydramine
9240:brompheniramine
9214:
9143:
8942:
8908:Levomilnacipran
8866:
8674:
8666:
8663:
8649:
8547:brompheniramine
8531:
8495:
8419:
8218:
8179:Levomilnacipran
8142:
8113:Methylphenidate
8056:
7964:
7956:
7953:
7939:
7626:
7480:
7444:
7415:Methylphenidate
7390:Desoxypipradrol
7368:
7311:
7303:
7300:
7290:
7285:
7255:
7250:
7207:
7197:
7182:
7147:
7135:Antidepressants
7129:
7121:
7091:
7086:
7085:
7070:Clinical trials
7049:
6953:
6934:dexmedetomidine
6906:Antiadrenergics
6903:
6902:
6894:
6871:
6835:
6820:
6805:
6790:
6775:
6760:
6748:Antidepressants
6742:
6705:
6698:
6697:
6689:
6671:
6510:Benzodiazepines
6500:
6492:
6488:
6478:
6452:
6448:
6438:
6428:
6398:
6393:
6392:
6377:Clinical trials
6352:
6291:
6276:
6272:
6264:
6249:lithium citrate
6197:
6176:
6159:
6156:
6146:
6099:
6096:
6086:
6062:Tranylcypromine
5968:
5947:
5931:
5903:
5893:
5745:
5731:
5706:
5615:
5597:
5587:
5564:
5554:
5531:
5521:
5498:
5488:
5465:
5455:
5436:Levomilnacipran
5417:
5407:
5359:
5345:
5327:
5320:Antidepressants
5317:
5270:
5265:
5264:
5254:
5252:
5245:www.justice.gov
5239:
5238:
5234:
5217:
5216:
5212:
5191:
5187:
5179:
5168:
5164:
5163:
5159:
5138:
5134:
5124:
5122:
5113:
5112:
5108:
5098:
5096:
5085:
5081:
5071:
5069:
5054:
5050:
5040:
5038:
5025:
5024:
5020:
5010:
5008:
5004:
4997:
4993:
4992:
4988:
4978:
4977:
4973:
4928:
4921:
4889:
4885:
4854:
4850:
4805:
4801:
4756:
4752:
4713:
4709:
4664:
4660:
4650:
4648:
4635:
4634:
4630:
4625:
4618:
4587:
4583:
4576:
4562:
4558:
4548:
4546:
4533:
4532:
4525:
4480:
4476:
4436:
4432:
4425:
4411:
4407:
4376:
4372:
4333:
4326:
4291:JAMA Psychiatry
4286:
4282:
4251:
4247:
4240:
4222:
4215:
4205:
4203:
4202:on 16 June 2008
4194:
4193:
4189:
4150:
4146:
4115:
4111:
4080:
4076:
4044:
4040:
4009:
4005:
3960:
3956:
3946:
3944:
3932:
3928:
3927:
3923:
3913:
3911:
3898:
3897:
3893:
3883:
3881:
3868:
3867:
3863:
3832:
3828:
3801:
3797:
3752:
3748:
3703:
3699:
3668:
3661:
3651:
3649:
3636:
3635:
3628:
3583:
3576:
3566:
3564:
3557:
3553:
3505:
3496:
3451:
3447:
3416:
3412:
3402:
3400:
3396:
3385:
3379:
3375:
3365:
3363:
3359:
3348:
3342:
3338:
3328:
3326:
3309:
3305:
3295:
3293:
3289:
3282:
3278:
3277:
3273:
3242:
3238:
3207:(6): CD001396.
3193:
3189:
3152:
3148:
3116:
3112:
3069:
3065:
3025:
3021:
2990:
2986:
2955:(7): CD006534.
2941:
2937:
2882:
2878:
2833:
2829:
2803:
2802:
2798:
2753:
2749:
2728:
2727:
2723:
2713:
2711:
2698:
2697:
2693:
2683:
2681:
2668:
2667:
2663:
2653:
2651:
2624:
2623:
2619:
2609:
2607:
2598:
2597:
2593:
2583:
2581:
2573:
2572:
2568:
2558:
2556:
2543:
2542:
2538:
2514:
2510:
2500:
2498:
2485:
2484:
2480:
2470:
2468:
2455:
2454:
2450:
2440:
2438:
2429:
2428:
2407:
2376:
2353:
2322:
2301:
2291:
2289:
2285:
2274:
2268:
2264:
2254:
2252:
2243:
2242:
2235:
2225:
2223:
2205:
2201:
2191:
2189:
2180:
2179:
2175:
2165:
2163:
2151:
2150:
2146:
2136:
2134:
2133:on 19 June 2020
2121:
2120:
2113:
2108:
2096:
2079:
2058:
2049:
2044:
2012:
1985:
1961:
1952:allosteric site
1924:
1904:
1877:
1864:
1851:
1838:
1825:
1812:
1799:
1759:
1745:
1740:
1720:antiretrovirals
1715:
1705:fluoroquinolone
1677:antiarrhythmics
1602:St. John's wort
1539:
1512:
1471:
1458:
1445:
1410:
1404:
1396:Mackworth Clock
1388:
1383:
1258:
1233:
1201:cardiac disease
1110:
1094:
1074:
1057:
1021:
1012:
958:sexual problems
899:
897:
892:
889:
884:
879:
878:
867:
864:
859:
858:
832:
807:
794:
785:
779:
740:
716:
708:
688:
668:
648:
628:
608:
588:
571:
563:
543:
540:
531:
530:
491:
480:
437:Protein binding
427:Bioavailability
419:Pharmacokinetic
413:
394:
318:
273:
266:
247:
240:
137:
134:
133:
85:
81:
43:
28:
23:
22:
15:
12:
11:
5:
10970:
10960:
10959:
10957:Sigma agonists
10954:
10949:
10944:
10942:Isobenzofurans
10939:
10934:
10929:
10924:
10919:
10914:
10899:
10898:
10875:
10874:
10864:
10861:
10860:
10858:
10857:
10852:
10847:
10842:
10837:
10832:
10827:
10822:
10817:
10812:
10807:
10802:
10797:
10792:
10787:
10782:
10772:
10767:
10762:
10757:
10752:
10747:
10745:Chlorpromazine
10742:
10737:
10732:
10727:
10722:
10717:
10708:
10707:
10698:
10697:
10692:
10687:
10682:
10677:
10672:
10667:
10662:
10657:
10652:
10647:
10642:
10633:
10632:
10627:
10622:
10617:
10612:
10607:
10602:
10593:
10591:
10587:
10586:
10584:
10583:
10578:
10573:
10568:
10558:
10553:
10548:
10543:
10538:
10533:
10528:
10523:
10513:
10503:
10498:
10493:
10488:
10483:
10478:
10469:
10468:
10463:
10458:
10453:
10448:
10443:
10438:
10433:
10428:
10419:
10418:
10413:
10408:
10403:
10398:
10393:
10388:
10383:
10375:
10370:
10365:
10360:
10355:
10350:
10345:
10340:
10335:
10330:
10321:
10319:
10315:
10310:
10309:
10307:
10306:
10301:
10296:
10291:
10286:
10281:
10276:
10271:
10266:
10261:
10256:
10251:
10246:
10241:
10236:
10231:
10221:
10211:
10203:
10198:
10193:
10188:
10186:Chlorpromazine
10183:
10178:
10173:
10168:
10163:
10158:
10153:
10148:
10143:
10138:
10129:
10128:
10123:
10107:
10106:
10101:
10096:
10091:
10086:
10081:
10076:
10071:
10066:
10061:
10056:
10051:
10046:
10041:
10039:E-52862 (S1RA)
10036:
10031:
10026:
10021:
10016:
10011:
10006:
10001:
9996:
9991:
9986:
9981:
9972:
9971:
9966:
9961:
9956:
9951:
9946:
9941:
9936:
9931:
9926:
9921:
9916:
9911:
9906:
9904:Neuropeptide Y
9901:
9896:
9891:
9886:
9881:
9876:
9868:
9863:
9858:
9853:
9848:
9843:
9838:
9833:
9828:
9823:
9818:
9813:
9808:
9803:
9798:
9793:
9788:
9786:Dextrallorphan
9783:
9773:
9763:
9758:
9753:
9748:
9743:
9733:
9728:
9723:
9718:
9713:
9708:
9703:
9698:
9693:
9688:
9683:
9674:
9672:
9668:
9663:
9662:
9656:Sigma receptor
9652:
9651:
9644:
9637:
9629:
9620:
9619:
9583:
9580:
9579:
9577:
9576:
9564:
9552:
9551:
9546:DAT enhancers:
9542:
9540:
9536:
9535:
9533:
9532:
9527:
9522:
9517:
9512:
9507:
9502:
9497:
9492:
9487:
9482:
9477:
9472:
9467:
9462:
9457:
9452:
9447:
9442:
9424:
9418:
9416:
9405:
9404:
9401:
9400:
9398:
9397:
9392:
9362:
9357:
9352:
9347:
9342:
9337:
9332:
9327:
9322:
9317:
9312:
9307:
9281:
9270:Antipsychotics
9267:
9264:tripelennamine
9248:dimenhydrinate
9244:chlorphenamine
9236:Antihistamines
9233:
9228:
9219:
9216:
9215:
9213:
9212:
9207:
9202:
9197:
9192:
9187:
9182:
9177:
9172:
9170:Cyanodothiepin
9167:
9162:
9157:
9148:
9145:
9144:
9142:
9141:
9131:
9126:
9121:
9116:
9111:
9106:
9101:
9096:
9091:
9086:
9081:
9076:
9071:
9066:
9061:
9056:
9051:
9046:
9041:
9036:
9031:
9026:
9021:
9016:
9011:
9006:
9001:
8996:
8991:
8986:
8981:
8976:
8971:
8966:
8961:
8956:
8947:
8944:
8943:
8941:
8940:
8935:
8930:
8925:
8920:
8915:
8910:
8905:
8900:
8895:
8893:Desvenlafaxine
8890:
8885:
8880:
8871:
8868:
8867:
8865:
8864:
8859:
8854:
8849:
8844:
8839:
8834:
8829:
8824:
8819:
8810:
8809:
8804:
8799:
8794:
8789:
8784:
8779:
8774:
8769:
8764:
8759:
8754:
8749:
8744:
8739:
8734:
8729:
8724:
8719:
8714:
8709:
8704:
8699:
8694:
8685:
8679:
8655:
8654:
8651:
8650:
8648:
8647:
8617:
8612:
8607:
8600:
8595:
8590:
8576:
8565:Antipsychotics
8562:
8559:tripelennamine
8551:chlorphenamine
8543:Antihistamines
8536:
8533:
8532:
8530:
8529:
8524:
8519:
8514:
8509:
8500:
8497:
8496:
8494:
8493:
8488:
8483:
8478:
8473:
8468:
8463:
8458:
8453:
8448:
8443:
8438:
8433:
8424:
8421:
8420:
8418:
8417:
8407:
8402:
8397:
8392:
8387:
8382:
8377:
8372:
8367:
8362:
8357:
8352:
8347:
8342:
8337:
8332:
8327:
8322:
8317:
8312:
8307:
8302:
8297:
8292:
8287:
8282:
8277:
8272:
8267:
8262:
8257:
8252:
8247:
8242:
8237:
8232:
8223:
8220:
8219:
8217:
8216:
8211:
8206:
8201:
8196:
8191:
8186:
8181:
8176:
8171:
8166:
8164:Desvenlafaxine
8161:
8156:
8147:
8144:
8143:
8141:
8140:
8135:
8130:
8125:
8120:
8115:
8110:
8105:
8100:
8095:
8090:
8085:
8080:
8075:
8070:
8061:
8058:
8057:
8055:
8054:
8049:
8044:
8039:
8034:
8029:
8024:
8019:
8014:
8009:
8004:
7999:
7994:
7989:
7984:
7975:
7969:
7945:
7944:
7941:
7940:
7938:
7937:
7932:
7930:Tripelennamine
7927:
7922:
7917:
7912:
7907:
7902:
7897:
7892:
7887:
7882:
7877:
7872:
7867:
7862:
7857:
7852:
7847:
7842:
7837:
7832:
7827:
7822:
7817:
7812:
7807:
7802:
7797:
7792:
7787:
7782:
7777:
7772:
7767:
7762:
7757:
7752:
7747:
7742:
7737:
7732:
7727:
7722:
7717:
7712:
7707:
7702:
7697:
7692:
7687:
7680:
7675:
7670:
7665:
7660:
7655:
7653:Amfonelic acid
7650:
7645:
7640:
7631:
7628:
7627:
7625:
7624:
7619:
7614:
7609:
7604:
7599:
7594:
7589:
7584:
7579:
7574:
7569:
7564:
7559:
7554:
7549:
7544:
7539:
7534:
7529:
7524:
7519:
7514:
7509:
7504:
7499:
7494:
7485:
7482:
7481:
7479:
7478:
7473:
7468:
7463:
7458:
7449:
7446:
7445:
7443:
7442:
7437:
7432:
7427:
7422:
7417:
7412:
7407:
7405:Ethylphenidate
7402:
7397:
7392:
7387:
7382:
7373:
7370:
7369:
7367:
7366:
7361:
7356:
7351:
7346:
7341:
7336:
7331:
7322:
7316:
7292:
7291:
7284:
7283:
7276:
7269:
7261:
7252:
7251:
7249:
7248:
7226:
7215:
7213:
7209:
7208:
7206:
7205:
7190:
7175:
7139:
7137:
7131:
7130:
7120:
7119:
7112:
7105:
7097:
7088:
7087:
7084:
7083:
7082:
7081:
7078:
7067:
7061:
7055:
7054:
7051:
7050:
7048:
7047:
7042:
7037:
7032:
7027:
7022:
7017:
7012:
7007:
7002:
6997:
6992:
6987:
6982:
6977:
6972:
6967:
6961:
6959:
6955:
6954:
6952:
6951:
6941:
6923:
6912:
6910:
6900:Sympatholytics
6896:
6895:
6893:
6892:
6887:
6881:
6879:
6877:Antipsychotics
6873:
6872:
6870:
6869:
6864:
6859:
6854:
6849:
6828:
6813:
6798:
6783:
6768:
6752:
6750:
6744:
6743:
6741:
6740:
6735:
6730:
6725:
6719:
6717:
6703:
6695:Gabapentinoids
6691:
6690:
6688:
6687:
6681:
6679:
6673:
6672:
6670:
6669:
6664:
6659:
6654:
6649:
6639:
6629:
6617:
6612:
6607:
6602:
6597:
6592:
6587:
6582:
6577:
6572:
6567:
6562:
6557:
6552:
6547:
6542:
6537:
6532:
6527:
6522:
6517:
6505:
6503:
6486:
6480:
6479:
6477:
6476:
6471:
6466:
6460:
6458:
6446:
6440:
6439:
6427:
6426:
6419:
6412:
6404:
6395:
6394:
6391:
6390:
6389:
6388:
6385:
6374:
6368:
6362:
6361:
6358:
6357:
6354:
6353:
6351:
6350:
6345:
6340:
6331:
6323:
6306:
6300:Ademetionine (
6296:
6293:
6292:
6282:
6281:
6278:
6277:
6275:
6274:
6270:
6262:
6252:
6238:
6233:
6202:
6199:
6198:
6186:
6185:
6182:
6181:
6178:
6177:
6175:
6174:
6165:
6163:
6154:
6148:
6147:
6145:
6144:
6139:
6134:
6129:
6124:
6119:
6114:
6105:
6103:
6094:
6088:
6087:
6085:
6084:
6075:
6074:
6065:
6064:
6059:
6054:
6049:
6044:
6039:
6034:
6029:
6024:
6019:
6014:
6009:
6004:
5999:
5994:
5989:
5980:
5978:
5970:
5969:
5957:
5956:
5953:
5952:
5949:
5948:
5946:
5945:
5939:
5937:
5933:
5932:
5930:
5929:
5924:
5919:
5914:
5908:
5906:
5895:
5894:
5892:
5891:
5886:
5881:
5876:
5871:
5866:
5861:
5856:
5851:
5846:
5841:
5836:
5831:
5826:
5821:
5819:Imipraminoxide
5816:
5811:
5806:
5801:
5796:
5791:
5786:
5781:
5776:
5771:
5766:
5761:
5756:
5750:
5748:
5733:
5732:
5716:
5715:
5712:
5711:
5708:
5707:
5705:
5704:
5699:
5694:
5689:
5684:
5679:
5674:
5669:
5664:
5659:
5654:
5649:
5644:
5639:
5634:
5629:
5623:
5621:
5617:
5616:
5614:
5613:
5608:
5602:
5600:
5589:
5588:
5586:
5585:
5580:
5575:
5569:
5567:
5556:
5555:
5553:
5552:
5547:
5542:
5536:
5534:
5523:
5522:
5520:
5519:
5514:
5509:
5503:
5501:
5490:
5489:
5487:
5486:
5481:
5476:
5470:
5468:
5457:
5456:
5454:
5453:
5448:
5443:
5438:
5433:
5428:
5426:Desvenlafaxine
5422:
5420:
5409:
5408:
5406:
5405:
5400:
5395:
5390:
5385:
5380:
5375:
5370:
5364:
5362:
5347:
5346:
5329:
5328:
5316:
5315:
5308:
5301:
5293:
5287:
5286:
5269:
5268:External links
5266:
5263:
5262:
5232:
5210:
5185:
5157:
5132:
5106:
5079:
5048:
5018:
4986:
4971:
4919:
4883:
4848:
4819:(5): 409–418.
4799:
4750:
4707:
4678:(4): 185–196.
4658:
4628:
4616:
4581:
4574:
4556:
4523:
4494:(3): 287–290.
4474:
4447:(6): 626–633.
4430:
4424:978-0962652370
4423:
4405:
4386:(2): 299–305.
4370:
4324:
4297:(4): 436–443.
4280:
4245:
4238:
4213:
4187:
4160:(3): 125–127.
4144:
4125:(3): 359–360.
4109:
4074:
4038:
4003:
3954:
3921:
3891:
3861:
3842:(6): 834–835.
3826:
3795:
3766:(5): e011200.
3746:
3697:
3678:(3): 404–408.
3659:
3626:
3597:(3): e034560.
3574:
3551:
3494:
3445:
3410:
3373:
3336:
3303:
3271:
3236:
3187:
3146:
3127:(2): 121–129.
3110:
3063:
3019:
2984:
2935:
2876:
2847:(2): 214–232.
2827:
2796:
2747:
2721:
2691:
2661:
2617:
2591:
2566:
2536:
2508:
2478:
2448:
2405:
2386:(4): 281–290.
2351:
2332:(1): 121–128.
2299:
2262:
2233:
2199:
2188:. 21 June 2022
2173:
2144:
2123:"Escitalopram"
2110:
2109:
2107:
2104:
2103:
2102:
2095:
2092:
2078:
2075:
2057:
2054:
2048:
2045:
2043:
2040:
2011:
2008:
1984:
1981:
1965:P-glycoprotein
1960:
1957:
1922:
1907:
1906:
1902:
1899:
1893:
1892:
1889:
1883:
1882:
1879:
1875:
1870:
1869:
1866:
1862:
1857:
1856:
1853:
1849:
1844:
1843:
1840:
1836:
1831:
1830:
1827:
1823:
1818:
1817:
1814:
1810:
1805:
1804:
1801:
1797:
1792:
1791:
1788:
1782:
1781:
1778:
1772:
1771:
1768:
1762:
1761:
1757:
1754:
1744:
1741:
1739:
1736:
1713:
1689:antihistamines
1681:antipsychotics
1671:on platelets.
1649:anticoagulants
1641:mefenamic acid
1511:
1508:
1506:, citalopram.
1470:
1467:
1457:
1454:
1444:
1441:
1406:Main article:
1403:
1400:
1387:
1384:
1382:
1381:
1376:
1373:
1368:
1362:
1357:
1352:
1346:
1340:
1334:
1328:
1323:
1318:
1313:
1308:
1306:Dilated pupils
1303:
1298:
1295:
1290:
1284:
1279:
1274:
1269:
1262:
1257:
1254:
1253:
1252:
1249:
1246:
1243:
1240:
1239:Headache (24%)
1232:
1229:
1182:antiarrhythmic
1109:
1106:
1093:
1090:
1073:
1070:
1056:
1053:
1045:panic disorder
1020:
1017:
939:taken by mouth
923:antidepressant
906:
905:
894:
893:
891:
890:
887:
885:
882:
874:
873:
872:
869:
868:
866:
865:
862:
854:
853:
852:
849:
848:
840:
834:
833:
831:
830:
822:
820:
812:
811:
805:
799:
798:
792:
783:
777:
772:
766:
765:
761:
760:
750:
742:
741:
739:
738:
725:
723:
710:
709:
707:
706:
698:
696:
690:
689:
687:
686:
678:
676:
670:
669:
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629:
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610:
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553:
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545:
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541:
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505:
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486:
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467:
449:
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429:
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384:
371:
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333:
331:
325:
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242:
241:
239:
238:
220:
218:
212:
211:
204:
198:
197:
190:
180:
179:
166:)-Citalopram;
160:
156:
155:
152:
146:
145:
79:
75:
74:
70:
69:
61:
60:
26:
9:
6:
4:
3:
2:
10969:
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10953:
10950:
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10935:
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10923:
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10915:
10913:
10910:
10909:
10907:
10897:
10887:
10886:
10883:
10872:
10871:
10868:
10862:
10856:
10853:
10851:
10848:
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10843:
10841:
10838:
10836:
10833:
10831:
10828:
10826:
10823:
10821:
10818:
10816:
10813:
10811:
10808:
10806:
10803:
10801:
10798:
10796:
10793:
10791:
10788:
10786:
10783:
10780:
10776:
10773:
10771:
10768:
10766:
10763:
10761:
10758:
10756:
10753:
10751:
10748:
10746:
10743:
10741:
10738:
10736:
10733:
10731:
10728:
10726:
10723:
10721:
10718:
10716:
10713:
10710:
10709:
10706:
10703:
10700:
10699:
10696:
10693:
10691:
10688:
10686:
10683:
10681:
10678:
10676:
10673:
10671:
10668:
10666:
10663:
10661:
10658:
10656:
10653:
10651:
10648:
10646:
10643:
10641:
10638:
10635:
10634:
10631:
10630:Tenocyclidine
10628:
10626:
10623:
10621:
10618:
10616:
10613:
10611:
10608:
10606:
10603:
10601:
10598:
10595:
10594:
10592:
10588:
10582:
10579:
10577:
10574:
10572:
10569:
10564:
10559:
10557:
10554:
10552:
10549:
10547:
10544:
10542:
10539:
10537:
10534:
10532:
10529:
10527:
10524:
10519:
10514:
10509:
10504:
10502:
10499:
10497:
10494:
10492:
10489:
10487:
10484:
10482:
10479:
10477:
10474:
10471:
10470:
10467:
10464:
10462:
10459:
10457:
10454:
10452:
10449:
10447:
10444:
10442:
10439:
10437:
10434:
10432:
10429:
10427:
10424:
10421:
10420:
10417:
10414:
10412:
10409:
10407:
10406:Phencyclidine
10404:
10402:
10399:
10397:
10394:
10392:
10389:
10387:
10384:
10382:
10376:
10374:
10371:
10369:
10366:
10364:
10361:
10359:
10356:
10354:
10351:
10349:
10346:
10344:
10341:
10339:
10336:
10334:
10331:
10329:
10326:
10323:
10322:
10320:
10318:
10311:
10305:
10302:
10300:
10297:
10295:
10292:
10290:
10287:
10285:
10282:
10280:
10277:
10275:
10272:
10270:
10267:
10265:
10262:
10260:
10257:
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10250:
10247:
10245:
10242:
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10237:
10235:
10232:
10227:
10222:
10217:
10212:
10210:
10204:
10202:
10199:
10197:
10194:
10192:
10189:
10187:
10184:
10182:
10179:
10177:
10176:Amitriptyline
10174:
10172:
10169:
10167:
10164:
10162:
10159:
10157:
10154:
10152:
10149:
10147:
10144:
10142:
10139:
10137:
10134:
10131:
10130:
10127:
10124:
10122:
10119:
10115:
10112:
10109:
10108:
10105:
10102:
10100:
10097:
10095:
10092:
10090:
10087:
10085:
10082:
10080:
10077:
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10072:
10070:
10067:
10065:
10062:
10060:
10057:
10055:
10052:
10050:
10047:
10045:
10042:
10040:
10037:
10035:
10032:
10030:
10027:
10025:
10022:
10020:
10017:
10015:
10012:
10010:
10007:
10005:
10002:
10000:
9997:
9995:
9992:
9990:
9987:
9985:
9982:
9980:
9977:
9974:
9973:
9970:
9967:
9965:
9962:
9960:
9957:
9955:
9952:
9950:
9947:
9945:
9942:
9940:
9937:
9935:
9932:
9930:
9927:
9925:
9922:
9920:
9917:
9915:
9912:
9910:
9907:
9905:
9902:
9900:
9897:
9895:
9892:
9890:
9889:Methoxetamine
9887:
9885:
9882:
9880:
9877:
9875:
9869:
9867:
9864:
9862:
9859:
9857:
9854:
9852:
9849:
9847:
9844:
9842:
9839:
9837:
9834:
9832:
9829:
9827:
9824:
9822:
9819:
9817:
9814:
9812:
9809:
9807:
9804:
9802:
9799:
9797:
9794:
9792:
9789:
9787:
9784:
9781:
9777:
9774:
9771:
9767:
9764:
9762:
9759:
9757:
9754:
9752:
9749:
9747:
9744:
9739:
9734:
9732:
9729:
9727:
9724:
9722:
9719:
9717:
9714:
9712:
9709:
9707:
9704:
9702:
9699:
9697:
9694:
9692:
9689:
9687:
9684:
9682:
9679:
9676:
9675:
9673:
9671:
9664:
9660:
9657:
9650:
9645:
9643:
9638:
9636:
9631:
9630:
9627:
9616:
9615:
9611:
9607:
9606:Serotonergics
9603:
9602:Dopaminergics
9599:
9595:
9591:
9588:
9581:
9575:
9572:
9568:
9565:
9563:
9560:
9559:Agonist-like:
9557:
9554:
9553:
9550:
9547:
9544:
9543:
9541:
9537:
9531:
9528:
9526:
9523:
9521:
9520:Tetrabenazine
9518:
9516:
9513:
9511:
9508:
9506:
9503:
9501:
9498:
9496:
9493:
9491:
9488:
9486:
9483:
9481:
9478:
9476:
9473:
9471:
9468:
9466:
9463:
9461:
9458:
9456:
9453:
9451:
9448:
9446:
9443:
9440:
9436:
9432:
9428:
9425:
9423:
9420:
9419:
9417:
9412:
9406:
9396:
9393:
9390:
9386:
9382:
9378:
9374:
9370:
9366:
9363:
9361:
9358:
9356:
9353:
9351:
9348:
9346:
9343:
9341:
9338:
9336:
9333:
9331:
9328:
9326:
9323:
9321:
9318:
9316:
9313:
9311:
9308:
9305:
9304:phencyclidine
9301:
9300:methoxetamine
9297:
9293:
9289:
9285:
9282:
9279:
9275:
9271:
9268:
9265:
9261:
9257:
9253:
9249:
9245:
9241:
9237:
9234:
9232:
9229:
9227:
9224:
9221:
9220:
9217:
9211:
9210:Protriptyline
9208:
9206:
9203:
9201:
9200:Nortriptyline
9198:
9196:
9193:
9191:
9188:
9186:
9183:
9181:
9178:
9176:
9173:
9171:
9168:
9166:
9163:
9161:
9158:
9156:
9155:Amitriptyline
9153:
9150:
9149:
9146:
9139:
9135:
9132:
9130:
9127:
9125:
9122:
9120:
9119:Tedatioxetine
9117:
9115:
9112:
9110:
9107:
9105:
9102:
9100:
9097:
9095:
9092:
9090:
9087:
9085:
9082:
9080:
9077:
9075:
9072:
9070:
9067:
9065:
9062:
9060:
9057:
9055:
9052:
9050:
9047:
9045:
9042:
9040:
9037:
9035:
9032:
9030:
9027:
9025:
9022:
9020:
9017:
9015:
9012:
9010:
9007:
9005:
9002:
9000:
8997:
8995:
8992:
8990:
8987:
8985:
8982:
8980:
8979:Centanafadine
8977:
8975:
8972:
8970:
8967:
8965:
8962:
8960:
8957:
8955:
8952:
8949:
8948:
8945:
8939:
8936:
8934:
8931:
8929:
8926:
8924:
8923:N-Methyl-PPPA
8921:
8919:
8916:
8914:
8911:
8909:
8906:
8904:
8901:
8899:
8896:
8894:
8891:
8889:
8886:
8884:
8881:
8879:
8876:
8873:
8872:
8869:
8863:
8860:
8858:
8855:
8853:
8850:
8848:
8845:
8843:
8840:
8838:
8835:
8833:
8830:
8828:
8825:
8823:
8820:
8818:
8815:
8812:
8811:
8808:
8805:
8803:
8800:
8798:
8795:
8793:
8790:
8788:
8785:
8783:
8780:
8778:
8775:
8773:
8770:
8768:
8765:
8763:
8762:Norfluoxetine
8760:
8758:
8755:
8753:
8750:
8748:
8745:
8743:
8740:
8738:
8735:
8733:
8730:
8728:
8725:
8723:
8720:
8718:
8715:
8713:
8710:
8708:
8705:
8703:
8702:Centpropazine
8700:
8698:
8695:
8693:
8690:
8687:
8686:
8683:
8680:
8673:
8662:
8656:
8645:
8641:
8637:
8633:
8629:
8625:
8624:desmetramadol
8621:
8618:
8616:
8613:
8611:
8608:
8606:
8605:
8604:Ginkgo biloba
8601:
8599:
8596:
8594:
8591:
8588:
8587:phencyclidine
8584:
8580:
8577:
8574:
8570:
8566:
8563:
8560:
8556:
8552:
8548:
8544:
8541:
8538:
8537:
8534:
8528:
8525:
8523:
8520:
8518:
8515:
8513:
8510:
8508:
8505:
8502:
8501:
8498:
8492:
8489:
8487:
8486:Protriptyline
8484:
8482:
8481:Nortriptyline
8479:
8477:
8474:
8472:
8469:
8467:
8464:
8462:
8459:
8457:
8454:
8452:
8449:
8447:
8444:
8442:
8439:
8437:
8434:
8432:
8431:Amitriptyline
8429:
8426:
8425:
8422:
8415:
8411:
8408:
8406:
8403:
8401:
8398:
8396:
8395:Tedatioxetine
8393:
8391:
8388:
8386:
8383:
8381:
8378:
8376:
8373:
8371:
8368:
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8281:
8278:
8276:
8273:
8271:
8268:
8266:
8263:
8261:
8258:
8256:
8255:Centanafadine
8253:
8251:
8248:
8246:
8243:
8241:
8238:
8236:
8233:
8231:
8228:
8225:
8224:
8221:
8215:
8212:
8210:
8207:
8205:
8202:
8200:
8197:
8195:
8194:N-Methyl-PPPA
8192:
8190:
8187:
8185:
8182:
8180:
8177:
8175:
8172:
8170:
8167:
8165:
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7970:
7963:
7952:
7946:
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7933:
7931:
7928:
7926:
7923:
7921:
7920:Tedatioxetine
7918:
7916:
7913:
7911:
7908:
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7898:
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7543:
7542:Ioflupane (I)
7540:
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7464:
7462:
7459:
7457:
7454:
7453:Pyrrolidines:
7451:
7450:
7447:
7441:
7440:Tenocyclidine
7438:
7436:
7433:
7431:
7428:
7426:
7425:Phencyclidine
7423:
7421:
7418:
7416:
7413:
7411:
7408:
7406:
7403:
7401:
7398:
7396:
7393:
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7028:
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7018:
7016:
7015:Phenaglycodol
7013:
7011:
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7001:
6998:
6996:
6993:
6991:
6988:
6986:
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6963:
6962:
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6949:
6945:
6944:Beta blockers
6942:
6939:
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6657:Chlormezanone
6655:
6653:
6650:
6647:
6643:
6640:
6637:
6636:phenobarbital
6633:
6630:
6628:
6625:
6621:
6618:
6616:
6613:
6611:
6608:
6606:
6603:
6601:
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6313:
6312:neurosteroids
6310:
6307:
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6297:
6294:
6290:Miscellaneous
6287:
6283:
6268:
6267:levothyroxine
6260:
6256:
6253:
6250:
6246:
6242:
6239:
6237:
6234:
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6227:
6223:
6219:
6215:
6214:brexpiprazole
6211:
6207:
6204:
6203:
6200:
6196:
6191:
6187:
6173:
6170:
6169:Irreversible:
6167:
6166:
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6149:
6143:
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6125:
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6003:
6002:Isocarboxazid
6000:
5998:
5995:
5993:
5990:
5988:
5985:
5984:Irreversible:
5982:
5981:
5979:
5977:Non-selective
5975:
5971:
5967:
5962:
5958:
5944:
5941:
5940:
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5874:Protriptyline
5872:
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5862:
5860:
5857:
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5849:Nortriptyline
5847:
5845:
5844:Nitroxazepine
5842:
5840:
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5832:
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5784:Demexiptiline
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5759:Amitriptyline
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5703:
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5678:
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5673:
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5094:
5091:. FirstWord.
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5031:Gdziepolek.pl
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3035:
3031:
3023:
3015:
3011:
3007:
3003:
2999:
2996:(in French).
2995:
2988:
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2971:
2966:
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2954:
2950:
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2899:
2896:(8): e42003.
2895:
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2872:
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2863:
2858:
2854:
2850:
2846:
2842:
2838:
2831:
2823:
2819:
2815:
2811:
2807:
2806:NIHR Evidence
2800:
2792:
2788:
2783:
2778:
2774:
2770:
2766:
2762:
2758:
2751:
2743:
2739:
2735:
2734:NIHR Evidence
2731:
2725:
2709:
2705:
2701:
2695:
2679:
2675:
2671:
2665:
2649:
2644:
2639:
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2606:. 2 July 2024
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2250:
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2187:
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2098:
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2074:
2070:
2068:
2064:
2053:
2039:
2037:
2033:
2029:
2021:
2016:
2007:
2006:citalopram.
2005:
2001:
1998:
1994:
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1966:
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1698:
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1678:
1672:
1670:
1667:via blocking
1666:
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1659:, and garlic
1658:
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1217:
1215:
1211:
1206:
1202:
1198:
1194:
1189:
1187:
1183:
1178:
1177:amitriptyline
1174:
1168:
1166:
1161:
1157:
1153:
1149:
1145:
1141:
1138:
1134:
1129:
1127:
1123:
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1052:
1050:
1046:
1042:
1038:
1034:
1030:
1026:
1016:
1010:
1006:
1002:
1001:United States
997:
996:-citalopram.
995:
991:
987:
983:
979:
975:
974:breastfeeding
971:
967:
963:
962:feeling tired
959:
955:
951:
946:
944:
940:
936:
932:
928:
924:
920:
916:
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895:
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844:
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839:
835:
828:
824:
823:
821:
818:
813:
806:
804:
800:
773:
771:
767:
762:
758:
754:
751:
749:
747:ECHA InfoCard
743:
735:
731:
730:DTXSID8048440
727:
726:
724:
715:
711:
704:
700:
699:
697:
695:
691:
684:
680:
679:
677:
675:
671:
664:
660:
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651:
644:
640:
639:
637:
635:
631:
624:
620:
619:
617:
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611:
604:
600:
599:
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584:
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579:
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566:
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546:
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522:
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494:
487:
484:
479:
475:
473:
469:
465:
461:
457:
453:
450:
448:
444:
441:~55–56% (low)
440:
438:
434:
430:
428:
424:
420:
416:
409:
407: Rx-only
400:
397:
385:
382:
372:
370:
361:
358:
348:
345:
335:
334:
332:
330:
326:
321:
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219:
217:
213:
209:
205:
203:
199:
195:
191:
189:
185:
181:
177:
173:
170:-Citalopram;
169:
165:
161:
157:
153:
151:
147:
140:
138:pronunciation
130:
80:
78:Pronunciation
76:
73:Clinical data
71:
67:
62:
58:
53:
45:
41:
37:
33:
19:
10866:
10865:
10820:Promethazine
10805:Perphenazine
10785:Fluphenazine
10760:Clocapramine
10735:Carvotroline
10711:
10701:
10637:Antagonists:
10636:
10596:
10472:
10423:Antagonists:
10422:
10324:
10196:Clomipramine
10132:
10117:
10110:
10089:Progesterone
9976:Antagonists:
9975:
9939:Pregnenolone
9826:Escitalopram
9825:
9746:Cloperastine
9721:Blarcamesine
9677:
9586:
9585:
9570:
9558:
9555:
9545:
9455:Bietaserpine
9427:Amphetamines
9350:Mifepristone
9340:Medifoxamine
9222:
9165:Clomipramine
9160:Cianopramine
9151:
9004:Diclofensine
8974:Brasofensine
8950:
8874:
8862:Vortioxetine
8813:
8732:Escitalopram
8731:
8688:
8610:Indeloxazine
8602:
8539:
8522:Oxaprotiline
8503:
8491:Trimipramine
8446:Clomipramine
8441:Cianopramine
8436:Butriptyline
8427:
8280:Diclofensine
8250:Brasofensine
8226:
8150:
8138:Solriamfetol
8064:
8047:Teniloxazine
8007:Esreboxetine
7978:
7910:Solriamfetol
7830:Medifoxamine
7720:Dimethocaine
7710:Diclofensine
7682:
7634:
7522:Difluoropine
7517:Dichloropane
7502:Brasofensine
7488:
7476:Pyrovalerone
7452:
7377:Piperidines:
7376:
7326:Piperazines:
7325:
7233:aripiprazole
7202:clomipramine
7156:escitalopram
7155:
6985:Lorpiprazole
6975:Fabomotizole
6965:Benzoctamine
6867:Vortioxetine
6843:
6810:clomipramine
6765:escitalopram
6764:
6652:Carisoprodol
6632:Barbiturates
6623:
6508:
6474:Tandospirone
6334:Oxitriptan (
6326:
6210:aripiprazole
6168:
6117:Metralindole
6108:
6078:
6068:
6047:Pivhydrazine
6037:Pheniprazine
5983:
5889:Trimipramine
5879:Quinupramine
5779:Clomipramine
5774:Butriptyline
5697:Teniloxazine
5692:Tandospirone
5677:Metryptamine
5672:Medifoxamine
5657:Indeloxazine
5611:Vortioxetine
5373:Escitalopram
5372:
5279:
5253:. Retrieved
5244:
5235:
5227:the original
5222:
5213:
5205:the original
5198:
5188:
5177:the original
5172:
5160:
5152:the original
5145:
5135:
5123:. Retrieved
5109:
5097:. Retrieved
5082:
5070:. Retrieved
5061:
5051:
5039:. Retrieved
5035:the original
5030:
5021:
5009:. Retrieved
4989:
4980:
4974:
4939:
4935:
4900:(1): 31–40.
4897:
4893:
4886:
4861:
4857:
4851:
4816:
4812:
4802:
4767:
4763:
4753:
4723:(1): 23–32.
4720:
4716:
4710:
4675:
4671:
4661:
4649:. Retrieved
4640:
4631:
4594:
4590:
4584:
4565:
4559:
4547:. Retrieved
4538:
4491:
4487:
4477:
4444:
4440:
4433:
4414:
4408:
4383:
4379:
4373:
4340:
4336:
4294:
4290:
4283:
4261:(1): 29–34.
4258:
4254:
4248:
4225:
4204:. Retrieved
4200:the original
4190:
4157:
4153:
4147:
4122:
4118:
4112:
4087:
4083:
4077:
4052:
4048:
4041:
4019:(19): 1987.
4016:
4012:
4006:
3971:
3967:
3957:
3945:. Retrieved
3936:
3924:
3912:. Retrieved
3903:
3894:
3882:. Retrieved
3873:
3864:
3839:
3835:
3829:
3804:
3798:
3763:
3759:
3749:
3714:
3710:
3700:
3675:
3671:
3650:. Retrieved
3594:
3590:
3565:. Retrieved
3554:
3546:
3519:(2): E5–E6.
3516:
3512:
3462:
3458:
3448:
3426:(1): 31–36.
3423:
3419:
3413:
3403:22 September
3401:. Retrieved
3389:
3376:
3366:22 September
3364:. Retrieved
3352:
3339:
3327:. Retrieved
3316:
3306:
3294:. Retrieved
3274:
3252:(1): 27–32.
3249:
3245:
3239:
3204:
3200:
3190:
3163:
3159:
3149:
3124:
3120:
3113:
3080:
3076:
3066:
3033:
3029:
3022:
3000:(1): 86–96.
2997:
2993:
2987:
2952:
2948:
2938:
2893:
2889:
2879:
2844:
2840:
2830:
2805:
2799:
2764:
2760:
2750:
2733:
2724:
2712:. Retrieved
2703:
2694:
2682:. Retrieved
2673:
2664:
2652:. Retrieved
2633:
2629:
2620:
2610:30 September
2608:. Retrieved
2603:
2594:
2582:. Retrieved
2578:
2569:
2557:. Retrieved
2548:
2539:
2530:10665/371090
2520:
2511:
2499:. Retrieved
2490:
2481:
2469:. Retrieved
2460:
2451:
2439:. Retrieved
2383:
2379:
2329:
2325:
2290:. Retrieved
2278:
2265:
2253:. Retrieved
2248:
2224:. Retrieved
2202:
2190:. Retrieved
2185:
2176:
2164:. Retrieved
2156:
2147:
2135:. Retrieved
2131:the original
2126:
2084:
2080:
2071:
2059:
2056:Legal status
2050:
2025:
2003:
1988:
1986:
1962:
1933:
1910:
1738:Pharmacology
1673:
1626:
1599:
1576:
1520:aripiprazole
1513:
1510:Interactions
1472:
1463:Apgar scores
1459:
1446:
1429:irritability
1411:
1393:
1389:
1360:Restlessness
1349:Paraesthesia
1293:Constipation
1289:(joint pain)
1259:
1242:Nausea (18%)
1234:
1221:hyponatremia
1218:
1190:
1169:
1156:moxifloxacin
1142:
1130:
1111:
1108:Side effects
1102:luteal phase
1095:
1075:
1066:evergreening
1062:
1058:
1022:
1019:Medical uses
998:
993:
977:
947:
918:
914:
911:Escitalopram
910:
909:
898:
843:Levorotatory
536:
497:~27–32 hours
490:Elimination
329:Legal status
323:Legal status
235:Escitalopram
216:License data
175:
171:
167:
163:
49:Escitalopram
44:
10855:Venlafaxine
10835:Remoxipride
10825:Propranolol
10750:Cinnarizine
10650:Lamotrigine
10546:Pentazocine
10541:Noribogaine
10531:Nemonapride
10363:Haloperidol
10289:Spipethiane
10254:Noribogaine
10249:Nemonapride
10244:KCR-12-83.1
10084:Pentazocine
10044:Haloperidol
9949:Pridopidine
9924:Pentazocine
9841:Fluvoxamine
9761:Cyclazocine
9598:Adrenergics
9525:Valbenazine
9515:Rose bengal
9460:Deserpidine
9431:amphetamine
9381:levorphanol
9325:Dextrorphan
9278:ziprasidone
9260:pheniramine
9195:Lofepramine
9175:Desipramine
9124:Tesofensine
9114:Sibutramine
9089:Perafensine
9049:JNJ-7925476
9044:Indatraline
8989:Dasotraline
8959:Amifitadine
8938:Venlafaxine
8918:Milnacipran
8817:Etoperidone
8797:Seproxetine
8787:Pirandamine
8767:Omiloxetine
8747:Fluvoxamine
8707:Cericlamine
8697:Alaproclate
8644:levorphanol
8573:ziprasidone
8555:pheniramine
8527:Setiptiline
8512:Maprotiline
8471:Lofepramine
8451:Desipramine
8400:Tesofensine
8390:Sibutramine
8365:Perafensine
8325:JNJ-7925476
8320:Indatraline
8265:Dasotraline
8235:Amifitadine
8214:Venlafaxine
8189:Milnacipran
8118:Nomifensine
8083:Fencamfamin
8012:Lortalamine
8002:Edivoxetine
7992:Ciclazindol
7987:Alseroxylon
7935:Venlafaxine
7915:Tametraline
7905:Sibutramine
7880:Perafensine
7860:Nomifensine
7790:Indatraline
7765:Fencamfamin
7740:DOV-216,303
7735:DOV-102,677
7695:Dasotraline
7690:Ciclazindol
7648:Armodafinil
7643:Amifitadine
7592:Tesofensine
7400:Difemetorex
7245:risperidone
7223:haloperidol
7187:venlafaxine
7164:fluvoxamine
7066:from market
6995:Mepiprazole
6980:Hydroxyzine
6970:Cycloserine
6948:propranolol
6890:Flupentixol
6847:Agomelatine
6825:mirtazapine
6646:meprobamate
6580:Fludiazepam
6555:Clotiazepam
6550:Clorazepate
6431:Anxiolytics
6373:from market
6316:brexanolone
6230:risperidone
6127:Moclobemide
6109:Reversible:
6069:Reversible:
5992:Iproclozide
5927:Setiptiline
5922:Mirtazapine
5912:Maprotiline
5869:Propizepine
5854:Noxiptiline
5839:Metapramine
5829:Lofepramine
5799:Dimetacrine
5789:Desipramine
5662:Flupentixol
5647:Etryptamine
5632:Amisulpride
5627:Agomelatine
5573:Etoperidone
5550:Setiptiline
5545:Mirtazapine
5517:Nomifensine
5474:Atomoxetine
5451:Venlafaxine
5441:Milnacipran
5383:Fluvoxamine
5255:22 November
5056:Miranda H.
4864:(1): 1–13.
3947:27 November
3914:27 November
3884:27 November
2994:L'Encéphale
2501:13 February
2471:31 December
2441:28 December
2292:6 September
2255:31 December
2047:Brand names
1936:selectivity
1708:antibiotics
1697:mizolastine
1661:supplements
1591:fluvoxamine
1548:desipramine
1544:peak levels
1524:risperidone
1477:. However,
1475:tachycardia
1173:venlafaxine
1148:QT interval
1137:suicidality
1049:agoraphobia
1043:(OCD), and
810: g·mol
753:100.244.188
683:CHEBI:36791
558:128196-01-0
519:Identifiers
472:Metabolites
202:MedlinePlus
159:Other names
150:Trade names
32:left handed
10906:Categories
10840:SL 82.0715
10755:Cinuperone
10730:Caramiphen
10725:Butaclamol
10625:Tapentadol
10556:Safinamide
10536:Nepinalone
10501:Clemastine
10496:5-MeO-DiPT
10491:5-MeO-DALT
10368:Ifenprodil
10333:Arketamine
10284:Selegiline
10279:Safinamide
10239:Imipramine
10201:Clorgiline
10191:Clemastine
10181:Azidopamil
10171:5-MeO-DiPT
10166:5-MeO-DALT
10099:Sertraline
9899:Nepinalone
9846:Ifenprodil
9836:Fluoxetine
9801:Dimemorfan
9770:prasterone
9731:Citalopram
9726:Captodiame
9706:Arketamine
9701:Amantadine
9659:modulators
9574:SoRI-20041
9567:SoRI-20040
9495:Ketanserin
9422:Amiodarone
9385:tapentadol
9345:Mesembrine
9315:Delucemine
9292:esketamine
9205:Pipofezine
9190:Imipramine
9109:SEP-228432
9104:SEP-228431
9074:Nefazodone
9059:Liafensine
9029:Fezolamine
9019:DOV-216303
9014:DOV-102677
8969:Bicifadine
8964:Ansofaxine
8903:Eclanamine
8898:Duloxetine
8883:Bicifadine
8857:Vilazodone
8827:Lubazodone
8822:Litoxetine
8807:Zimelidine
8802:Sertraline
8777:Paroxetine
8772:Panuramine
8742:Fluoxetine
8737:Femoxetine
8717:Dapoxetine
8712:Citalopram
8636:tapentadol
8615:Nefazodone
8598:Ephenidine
8593:Dopexamine
8476:Melitracen
8466:Imipramine
8385:SEP-228432
8380:SEP-228431
8350:Nefazodone
8335:Liafensine
8305:Fezolamine
8295:DOV-216303
8290:DOV-102677
8245:Bicifadine
8240:Ansofaxine
8199:Nafenodone
8174:Eclanamine
8169:Duloxetine
8128:Radafaxine
8108:Manifaxine
8093:Lefetamine
8068:Amineptine
8052:Viloxazine
8027:Reboxetine
8022:Nisoxetine
7900:Sertraline
7890:Radafaxine
7875:Oroxylin A
7820:Manifaxine
7810:Liafensine
7800:Lefetamine
7780:GYKI-52895
7770:Fezolamine
7755:Esketamine
7750:Ephenidine
7673:BTS 74,398
7663:Ansofaxine
7658:Amineptine
7537:FP-β-CPPIT
7532:FE-β-CPPIT
7471:Prolintane
7364:Vanoxerine
7359:Nefazodone
7241:quetiapine
7237:olanzapine
7172:sertraline
7168:paroxetine
7160:fluoxetine
7152:citalopram
7010:Oxaflozane
6938:guanfacine
6885:Quetiapine
6862:Vilazodone
6857:Tianeptine
6840:phenelzine
6780:duloxetine
6738:Pregabalin
6723:Gabapentin
6642:Carbamates
6605:Nordazepam
6560:Cloxazolam
6545:Clonazepam
6525:Bromazepam
6520:Alprazolam
6515:Adinazolam
6348:Tryptophan
6320:zuranolone
6226:quetiapine
6222:olanzapine
6218:lurasidone
6172:Selegiline
6162:-selective
6142:Toloxatone
6137:Tetrindole
6132:Pirlindole
6112:Eprobemide
6102:-selective
6082:Bifemelane
6072:Caroxazone
6032:Phenelzine
6017:Mebanazine
5997:Iproniazid
5884:Tianeptine
5864:Pipofezine
5834:Melitracen
5814:Imipramine
5794:Dibenzepin
5754:Amineptine
5702:Tianeptine
5687:Pivagabine
5682:Oxaflozane
5642:Esketamine
5606:Vilazodone
5578:Nefazodone
5507:Amineptine
5484:Viloxazine
5479:Reboxetine
5431:Duloxetine
5403:Zimelidine
5398:Sertraline
5393:Paroxetine
5378:Fluoxetine
5368:Citalopram
5125:19 January
5099:10 October
5072:10 October
5041:17 October
4637:"UpToDate"
3717:(4): E11.
2166:22 October
2106:References
2036:citalopram
2000:citalopram
1993:enantiomer
1868:>1,000
1855:>1,000
1816:>1,000
1803:>1,000
1728:saquinavir
1693:astemizole
1587:fluoxetine
1583:citalopram
1579:omeprazole
1552:metoprolol
1483:hypertonia
1479:dyskinesia
1421:brain zaps
1414:withdrawal
1287:Arthralgia
1277:Anorgasmia
1272:Anisocoria
1214:citalopram
1165:citalopram
1144:Citalopram
1126:anorgasmia
1055:Depression
1005:citalopram
986:citalopram
982:enantiomer
846:enantiomer
815:3D model (
803:Molar mass
703:ChEMBL1508
643:4O4S742ANY
614:ChemSpider
549:CAS Number
528:IUPAC name
447:Metabolism
286:Drug class
40:citalopram
38:form, see
10867:See also:
10845:SR-31747A
10830:Quinidine
10815:Proadifen
10800:Molindone
10775:Hypericin
10770:EMD-59983
10720:BMY-13980
10705:SKF-83959
10620:Naluzotan
10600:Berberine
10597:Agonists:
10551:RS-67,333
10486:4-MeO-PCP
10481:3-MeO-PCE
10396:Opipramol
10391:OPC-14523
10325:Agonists:
10264:RS-67,333
10209:-Deprenyl
10161:4-MeO-PCP
10141:3-MeO-PCP
10126:SOMCL-668
10118:Positive:
10114:Phenytoin
10104:SR-31742A
10079:PD-144418
10069:NPC-16377
9919:Opipramol
9914:OPC-14523
9909:Noscapine
9879:Memantine
9821:Eliprodil
9816:Donepezil
9691:5-MeO-DMT
9678:Agonists:
9587:See also:
9562:SoRI-9804
9510:Reserpine
9480:GBR-12935
9475:Efavirenz
9395:Roxindole
9373:methadone
9360:N-Me-5-HT
9330:Efavirenz
9288:3-MeO-PCP
9231:Amoxapine
9099:Pridefine
9069:Naphyrone
8933:Tofenacin
8852:Trazodone
8842:SB-649915
8837:Quipazine
8832:LY-393558
8757:Ifoxetine
8752:Indalpine
8628:methadone
8517:Mianserin
8507:Amoxapine
8375:Pridefine
8345:Naphyrone
8209:Tofenacin
8159:CP-39,332
8078:Fencamine
8073:Bupropion
8042:Tandamine
8037:Talsupram
7997:Daledalin
7895:Rimcazole
7885:Pridefine
7850:Modafinil
7775:Fluorenol
7745:Efavirenz
7678:Bupropion
7638:Adrafinil
7602:Tropoxane
7492:Altropane
7489:Tropanes:
7466:Naphyrone
7430:Pipradrol
7349:GBR-13098
7344:GBR-13069
7339:GBR-12935
7334:GBR-12783
7076:Phase III
7064:Withdrawn
7045:Validolum
7040:Tofisopam
7035:Tiagabine
7025:Picamilon
7005:Opipramol
6930:clonidine
6852:Bupropion
6795:trazodone
6685:Zopiclone
6677:Hypnotics
6667:Etifoxine
6615:Pinazepam
6600:Medazepam
6595:Lorazepam
6590:Ketazolam
6585:Halazepam
6530:Camazepam
6464:Buspirone
6383:Phase III
6371:Withdrawn
6236:Buspirone
6122:Minaprine
6057:Tedizolid
6052:Safrazine
6027:Octamoxin
6022:Nialamide
6012:Linezolid
6007:Isoniazid
5917:Mianserin
5859:Opipramol
5824:Iprindole
5804:Dosulepin
5769:Amoxapine
5725:Tricyclic
5583:Trazodone
5540:Mianserin
5512:Bupropion
5446:Tofenacin
5388:Indalpine
5337:Specific
4651:10 August
4539:Drugs.com
4033:0098-7484
3821:2636-834X
3296:23 August
2822:241309451
2584:30 August
2559:30 August
2461:Drugs.com
2087:kickbacks
1983:Chemistry
1973:quinidine
1969:verapamil
1925:receptors
1913:serotonin
1901:2,600 (IC
1732:lopinavir
1724:ritonavir
1701:macrolide
1657:vitamin E
1633:ibuprofen
1614:linezolid
1595:Bupropion
1456:Pregnancy
1450:anhedonia
1437:akathisia
1425:dizziness
1365:Sinusitis
1331:Impotence
1316:Dry mouth
1311:Dizziness
1265:Abnormal
1088:as well.
970:pregnancy
838:Chirality
503:Excretion
492:half-life
272:Routes of
246:Pregnancy
194:Monograph
188:Drugs.com
10947:Nitriles
10896:Medicine
10810:Pimozide
10765:Dezocine
10655:Naloxone
10615:Metaphit
10610:Fourphit
10590:Unsorted
10526:Ibogaine
10466:SAS-0132
10416:UKH-1114
10373:Ketamine
10358:DKR-1051
10353:DKR-1005
10234:Ibogaine
9866:L-687384
9861:Ketamine
9549:Luteolin
9500:Lobeline
9490:Ibogaine
9389:tramadol
9335:Hypidone
9296:ketamine
9274:loxapine
9134:Tropanes
9064:Mazindol
9054:JZ-IV-10
8888:CP-39332
8847:TGBA01AD
8640:tramadol
8583:ketamine
8569:loxapine
8410:Tropanes
8340:Mazindol
8330:JZ-IV-10
8032:Talopram
8017:Mazindol
7982:Amedalin
7840:Metaphit
7835:Mesocarb
7825:Mazindol
7795:Ketamine
7597:Troparil
7354:JJC8-088
7020:Phenibut
7000:Nicotine
6920:prazosin
6733:Phenibut
6713:blockers
6620:Prazepam
6610:Oxazepam
6575:Etizolam
6565:Diazepam
6540:Clobazam
6469:Gepirone
6456:agonists
6309:GABAkine
5987:Benmoxin
5943:Tiazesim
5667:Ketamine
5652:Gepirone
5249:Archived
5119:Archived
5093:Archived
5066:Archived
5002:Archived
4966:23670590
4914:16448580
4878:21901317
4843:28153641
4794:28858536
4745:15062534
4737:24045971
4702:24424469
4645:Archived
4611:15784664
4549:22 April
4543:Archived
4518:16120067
4469:29063004
4461:19710642
4365:43329515
4357:26135630
4311:23446732
4275:28778697
4206:9 August
4182:45460237
4174:27171568
4139:18480703
4104:17183922
4069:21616541
3998:27303087
3941:Archived
3908:Archived
3878:Archived
3874:Medscape
3856:29878443
3807:(0): 1.
3790:27194321
3760:BMJ Open
3741:23791140
3692:19556032
3646:Archived
3621:32169926
3591:BMJ Open
3563:. US FDA
3543:23422053
3489:23360890
3465:: f288.
3440:17453659
3394:Archived
3357:Archived
3323:Archived
3287:Archived
3266:16430968
3231:23744611
3182:26971233
3141:19961809
3105:72332967
3097:30712879
3058:43179425
3050:21034375
3014:22381728
2979:22786497
2930:22876296
2890:PLOS ONE
2871:32394557
2791:29477251
2714:15 March
2708:Archived
2684:15 March
2678:Archived
2654:15 March
2648:Archived
2579:ClinCalc
2553:Archived
2549:ClinCalc
2519:(2023).
2495:Archived
2493:. 2015.
2465:Archived
2435:Archived
2400:17375980
2346:24289655
2283:Archived
2249:DailyMed
2226:3 August
2220:Archived
2192:30 March
2137:25 April
2094:See also
2028:Lundbeck
2020:Lundbeck
1997:racemate
1938:for the
1917:reuptake
1770:0.8–1.1
1637:naproxen
1536:tramadol
1528:tramadol
1504:racemate
1469:Overdose
1417:symptoms
1375:Vomiting
1301:Diarrhea
990:racemate
937:. It is
919:Cipralex
901:(verify)
594:DrugBank
357:Class C1
299:ATC code
279:By mouth
248:category
230:DailyMed
10680:UMB-116
10675:UMB-103
10670:UMB-101
10665:UMB-100
10456:MIN-101
10446:CT-1812
10436:BD-1067
10431:BD-1008
10338:BD-1047
10274:Saffron
10259:RHL-033
10029:Dup-734
10014:BD-1067
10009:BD-1063
10004:BD-1060
9999:BD-1047
9994:BD-1031
9989:BD-1008
9934:PRE-084
9751:Cocaine
9716:BD-1052
9485:GZ-793A
9429:(e.g.,
9367:(e.g.,
9365:Opioids
9286:(e.g.,
9272:(e.g.,
9238:(e.g.,
9226:A-80426
9223:Others:
9185:Doxepin
9138:cocaine
9136:(e.g.,
9084:NS-2359
9079:Nefopam
9034:HDMP-28
9024:EXP-561
8984:Cocaine
8913:McN5652
8792:RTI-353
8622:(e.g.,
8620:Opioids
8581:(e.g.,
8567:(e.g.,
8545:(e.g.,
8540:Others:
8461:Doxepin
8414:cocaine
8412:(e.g.,
8360:NS-2359
8355:Nefopam
8310:HDMP-28
8300:EXP-561
8260:Cocaine
8184:McN5652
8103:LR-5182
7865:NS-2359
7855:Nefopam
7815:LR-5182
7760:EXP-561
7635:Others:
7587:RTI-336
7582:RTI-229
7577:RTI-177
7572:RTI-150
7567:RTI-126
7562:RTI-121
7557:RTI-113
7552:RTI-112
7512:Cocaine
7410:HDMP-28
7329:DBL-583
6990:Mebicar
6946:(e.g.,
6928:(e.g.,
6918:(e.g.,
6844:Others:
6838:(e.g.,
6823:(e.g.,
6808:(e.g.,
6793:(e.g.,
6778:(e.g.,
6763:(e.g.,
6644:(e.g.,
6634:(e.g.,
6627:Alpidem
6624:Others:
6241:Lithium
5809:Doxepin
5341:and/or
5011:7 April
4957:3773671
4834:5410405
4785:5606297
4693:4047306
4509:1884771
4400:8953171
4319:2065578
4230:446–449
3989:4896342
3781:4874104
3732:3692726
3652:5 March
3612:7069257
3534:3581598
3480:3558546
3222:7073417
2970:4204633
2921:3410906
2898:Bibcode
2862:7215080
2782:5889788
2674:Reuters
2010:History
1790:27,400
1710:, some
1687:, some
1606:ginseng
1568:CYP2C19
1532:codeine
1379:Yawning
1343:Myalgia
1339:changes
1326:Fatigue
1282:Anxiety
1186:sotalol
1039:(SAD),
1035:(GAD),
943:oxalate
925:of the
915:Lexapro
808:324.399
770:Formula
603:DB01175
569:PubChem
514:(minor)
456:CYP2C19
398:Rx-only
395:WARNING
367::
315:)
309: (
307:N06AB10
261: C
232::
208:a603005
36:racemic
18:Lexapro
10882:Portal
10695:YZ-185
10690:YZ-069
10685:YZ-011
10576:UMB-82
10571:UMB-23
10451:LR-172
10441:CM-156
10426:AC-927
10343:BD1063
10304:YKP10A
10269:RTI-55
10156:4-IPBS
10146:4C-T-2
10064:NE-100
10059:MS-377
10054:LR-172
10049:LR-132
10034:E-5842
10024:CM-156
9984:AC-927
9969:UMB-82
9964:UMB-23
9711:BD-737
9686:4-PPBP
9539:Others
9094:PRC200
9039:HP-505
8782:PIM-35
8370:PRC200
8315:HP-505
8123:O-2172
7870:O-2172
7547:RTI-55
7212:Others
7059:WHO-EM
7030:Selank
6958:Others
6366:WHO-EM
6079:Mixed:
5936:Others
5620:Others
5528:NaSSAs
4964:
4954:
4912:
4876:
4841:
4831:
4792:
4782:
4743:
4735:
4700:
4690:
4609:
4572:
4516:
4506:
4467:
4459:
4421:
4398:
4363:
4355:
4317:
4309:
4273:
4236:
4180:
4172:
4137:
4102:
4067:
4031:
3996:
3986:
3854:
3819:
3788:
3778:
3739:
3729:
3690:
3619:
3609:
3541:
3531:
3487:
3477:
3438:
3329:13 May
3264:
3229:
3219:
3180:
3139:
3103:
3095:
3077:Lancet
3056:
3048:
3012:
2977:
2967:
2928:
2918:
2869:
2859:
2820:
2789:
2779:
2761:Lancet
2398:
2344:
2208:Anvisa
1891:1,240
1881:2,000
1842:3,900
1829:2,500
1780:7,800
1629:NSAIDs
1572:CYP2E1
1564:CYP2C9
1560:CYP1A2
1556:CYP3A4
1540:
1516:CYP2D6
1492:plasma
1487:clonus
1485:, and
1371:Tremor
1337:Libido
1267:dreams
1203:, and
1124:, and
1118:libido
1104:only.
1013:
960:, and
954:nausea
856:SMILES
694:ChEMBL
663:D07913
623:129277
583:146570
464:CYP2D6
460:CYP3A4
392:
379:
369:℞-only
355:
342:
293:(SSRI)
228:
144:
10660:SM-21
10401:PB-28
10328:3-PPP
10151:4-IBP
9979:3-PPP
9681:3-PPP
9410:VMATs
7622:WF-33
7617:WF-31
7612:WF-23
7607:WF-11
7179:SNRIs
7144:SSRIs
6832:MAOIs
6817:TeCAs
6787:SARIs
6772:SNRIs
6757:SSRIs
6336:5-HTP
5900:TeCAs
5561:SARIs
5495:NDRIs
5414:SNRIs
5356:SSRIs
5180:(PDF)
5169:(PDF)
5062:WebMD
5005:(PDF)
4998:(PDF)
4741:S2CID
4465:S2CID
4361:S2CID
4315:S2CID
4178:S2CID
3933:(PDF)
3567:1 May
3397:(PDF)
3386:(PDF)
3360:(PDF)
3349:(PDF)
3290:(PDF)
3283:(PDF)
3101:S2CID
3054:S2CID
2818:S2CID
2286:(PDF)
2275:(PDF)
1760:(nM)
1753:Site
1622:MAOIs
1585:with
1570:, or
1496:serum
1355:Fever
1225:SIADH
1114:SSRIs
1092:Other
876:InChI
817:JSmol
674:ChEBI
512:feces
508:Urine
452:Liver
10645:AZ66
10640:AHD1
10581:W-18
10507:DiPT
10379:MDMA
10299:W-18
10215:DiPT
9872:MDMA
9856:IPAB
9737:CGRP
9450:AZIK
9439:MDMA
8928:PPPA
8671:SRIs
8660:SERT
8204:PPPA
7961:NRIs
7461:MDPV
7308:DRIs
7194:TCAs
6802:TCAs
6709:VDCC
6497:PAMs
6485:GABA
6445:5-HT
6435:N05B
6302:SAMe
5742:TCAs
5727:and
5462:NRIs
5324:N06A
5257:2020
5127:2009
5101:2007
5074:2007
5043:2020
5013:2007
4962:PMID
4910:PMID
4874:PMID
4839:PMID
4790:PMID
4733:PMID
4698:PMID
4653:2022
4607:PMID
4570:ISBN
4551:2018
4514:PMID
4457:PMID
4419:ISBN
4396:PMID
4353:PMID
4307:PMID
4271:PMID
4234:ISBN
4208:2015
4170:PMID
4135:PMID
4100:PMID
4065:PMID
4029:ISSN
4013:JAMA
3994:PMID
3949:2013
3916:2013
3886:2013
3852:PMID
3817:ISSN
3786:PMID
3737:PMID
3688:PMID
3654:2013
3617:PMID
3569:2024
3539:PMID
3485:PMID
3436:PMID
3405:2007
3368:2007
3331:2007
3298:2017
3262:PMID
3227:PMID
3205:2013
3178:PMID
3137:PMID
3093:PMID
3046:PMID
3010:PMID
2975:PMID
2953:2012
2926:PMID
2867:PMID
2787:PMID
2716:2020
2686:2020
2656:2020
2612:2024
2586:2024
2561:2024
2503:2018
2473:2017
2443:2017
2396:PMID
2342:PMID
2294:2022
2257:2023
2228:2023
2194:2024
2168:2023
2139:2015
2063:Teva
2030:and
1971:and
1921:5-HT
1897:hERG
1887:mACh
1822:5-HT
1809:5-HT
1796:5-HT
1766:SERT
1712:5-HT
1703:and
1175:and
933:and
917:and
654:KEGG
634:UNII
431:~80%
421:data
184:AHFS
10562:TMA
10517:DPT
10225:DPT
9445:APP
7950:NET
7668:BTQ
7507:CFT
7297:DAT
7125:OCD
6842:);
6265:),
6153:MAO
6093:MAO
5594:SMS
4952:PMC
4944:doi
4902:doi
4866:doi
4862:219
4829:PMC
4821:doi
4780:PMC
4772:doi
4725:doi
4721:387
4688:PMC
4680:doi
4599:doi
4595:352
4504:PMC
4496:doi
4449:doi
4388:doi
4384:685
4345:doi
4299:doi
4263:doi
4162:doi
4127:doi
4092:doi
4057:doi
4053:134
4021:doi
4017:301
3984:PMC
3976:doi
3844:doi
3809:doi
3776:PMC
3768:doi
3727:PMC
3719:doi
3680:doi
3607:PMC
3599:doi
3529:PMC
3521:doi
3475:PMC
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