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Lowest-observed-adverse-effect level

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defines LOAEL as the 'lowest level of a chemical stressor evaluated in a toxicity test that shows harmful effects on a plant or animal. While LOAELs and LOAECs are similar, they are not interchangeable. A LOAEL refers to a dose of chemical that is ingested, while a LOAEC refers to direct exposure to
91:, function, capacity, growth, development, or lifespan of a target organism distinguished from normal organisms of the same species under defined conditions of exposure. Federal agencies use the LOAEL during 262: 203:. Cincinnati, OH: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health. Publication No. 2020-106. 244: 40: 107: 335: 87:), is the lowest concentration or amount of a substance found by experiment or observation that causes an adverse alteration of 354: 58: 120: 277: 309: 36: 328: 364: 321: 145: 88: 8: 359: 268: 270:
Report for Congress: Agriculture: A Glossary of Terms, Programs, and Laws, 2005 Edition
238: 204: 177: 92: 166:"Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)" 305: 125: 348: 208: 98: 230: 182: 165: 198: 301: 150:
Environmental Health and Toxicology Specialized Information Services
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Duffus, J. H.; Nordberg, M.; Templeton, D. M. (2007).
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may be too technical for most readers to understand
346: 152:. U.S. Department of Health & Human Services 200:NIOSH Practices in Occupational Risk Assessment 111:a chemical (e.g., through gills or the skin). 329: 108:United States Environmental Protection Agency 243:: CS1 maint: multiple names: authors list ( 95:to set approval standards below this level. 81:lowest-observed-adverse-effect concentration 336: 322: 266: 181: 59:Learn how and when to remove this message 43:, without removing the technical details. 102:Hypothetical dose-response showing LOAEL 97: 347: 229:Registries, EPA, OEI, SOR, System Of. 228: 196: 41:make it understandable to non-experts 288: 73:lowest-observed-adverse-effect level 15: 13: 14: 376: 292: 261: This article incorporates 256: 121:No-observed-adverse-effect level 20: 278:Congressional Research Service 222: 138: 1: 131: 308:. You can help Knowledge by 7: 114: 10: 381: 287: 170:Pure and Applied Chemistry 355:Concentration indicators 209:10.26616/NIOSHPUB2020106 183:10.1351/pac200779071153 304:-related article is a 263:public domain material 231:"Terms & Acronyms" 103: 101: 197:NIOSH (March 2020). 104: 317: 316: 69: 68: 61: 372: 365:Toxicology stubs 338: 331: 324: 296: 289: 281: 275: 260: 259: 249: 248: 242: 234: 226: 220: 219: 217: 215: 194: 188: 187: 185: 161: 159: 157: 142: 64: 57: 53: 50: 44: 24: 23: 16: 380: 379: 375: 374: 373: 371: 370: 369: 345: 344: 343: 342: 285: 273: 267:Jasper Womach. 257: 253: 252: 236: 235: 227: 223: 213: 211: 195: 191: 155: 153: 144: 143: 139: 134: 117: 93:risk assessment 65: 54: 48: 45: 37:help improve it 34: 25: 21: 12: 11: 5: 378: 368: 367: 362: 357: 341: 340: 333: 326: 318: 315: 314: 297: 283: 282: 251: 250: 221: 189: 136: 135: 133: 130: 129: 128: 126:Reference dose 123: 116: 113: 67: 66: 28: 26: 19: 9: 6: 4: 3: 2: 377: 366: 363: 361: 358: 356: 353: 352: 350: 339: 334: 332: 327: 325: 320: 319: 313: 311: 307: 303: 298: 295: 291: 290: 286: 279: 272: 271: 264: 255: 254: 246: 240: 232: 225: 210: 206: 202: 201: 193: 184: 179: 175: 171: 167: 151: 147: 141: 137: 127: 124: 122: 119: 118: 112: 109: 100: 96: 94: 90: 86: 82: 78: 74: 63: 60: 52: 49:February 2018 42: 38: 32: 29:This article 27: 18: 17: 310:expanding it 299: 284: 269: 224: 212:. Retrieved 199: 192: 173: 169: 154:. Retrieved 149: 140: 105: 84: 80: 76: 72: 70: 55: 46: 30: 176:(7): 1153. 162:based upon 360:Toxicology 349:Categories 302:toxicology 156:January 9, 132:References 89:morphology 79:), or the 239:cite web 115:See also 214:18 July 35:Please 300:This 274:(PDF) 265:from 85:LOAEC 77:LOAEL 306:stub 245:link 216:2024 158:2016 106:The 71:The 205:doi 178:doi 39:to 351:: 276:. 241:}} 237:{{ 174:79 172:. 168:. 148:. 337:e 330:t 323:v 312:. 280:. 247:) 233:. 218:. 207:: 186:. 180:: 160:. 83:( 75:( 62:) 56:( 51:) 47:( 33:.

Index

help improve it
make it understandable to non-experts
Learn how and when to remove this message
morphology
risk assessment

United States Environmental Protection Agency
No-observed-adverse-effect level
Reference dose
"IUPAC glossary of terms used in toxicology - terms starting with L"
"Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)"
doi
10.1351/pac200779071153
NIOSH Practices in Occupational Risk Assessment
doi
10.26616/NIOSHPUB2020106
"Terms & Acronyms"
cite web
link
public domain material
Report for Congress: Agriculture: A Glossary of Terms, Programs, and Laws, 2005 Edition
Congressional Research Service
Stub icon
toxicology
stub
expanding it
v
t
e
Categories

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