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Michael M. Gottesman

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Chen, Chang-jie; Chin, Janice E.; Ueda, Kazumitsu; Clark, Douglas P.; Pastan, Ira; Gottesman, Michael M.; Roninson, Igor B. (1986), "Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells",
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Thiebaut, F.; Tsuruo, T.; Hamada, H.; Gottesman, M. M.; Pastan, I.; Willingham, M. C. (1987), "Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues",
176:, a research associate at the NIH, and an assistant professor at Harvard before taking a permanent position at the NIH in 1976. On August 1, 2022, Gottesman was succeeded as director of the 595: 545: 620: 610: 645: 304: 600: 873: 691: 605: 650: 531: 615: 590: 1010: 696: 630: 221: 585: 1055: 377: 635: 275:. Accessed April 20, 2023. "Michael Marc Gottesman was born on October 7, 1946 in Jersey City, New Jersey, and grew up in Flushing, New York." 1045: 747: 706: 1015: 722: 432:
Kimchi-Sarfaty, Chava; Oh, Jung Mi; Kim, In-Wha; Sauna, Zuben E.; Calcagno, Anna Maria; Ambudkar, Suresh V.; Gottesman, Michael M. (2007),
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efflux transporter associated with clinical resistance to anti-cancer agents. In 2007, he reported for the first time in
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This biography of a person who has held a non-elected position in the federal government of the United States is a
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Fellows of the American Society for Pharmacology and Experimental Therapeutics
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in biochemical sciences in 1966 from Harvard College, and received his M.D.
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His areas of expertise includes a major contribution to the discovery of
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National Institute of Arthritis and Musculoskeletal and Skin Diseases
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Fellows of the American Association for the Advancement of Science
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Impact of silent polymorphisms on tertiary structure and function
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National Institute of Diabetes and Digestive and Kidney Diseases
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National Institute on Deafness and Other Communication Disorders
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National Institute on Minority Health and Health Disparities
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National Institute of Biomedical Imaging and Bioengineering
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in 1970. He then worked as an intern and resident at the
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National Center for Complementary and Integrative Health
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National Institute of Child Health and Human Development
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National Institute of Neurological Disorders and Stroke
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National Institutes of Health Director's Pioneer Award
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National Institute of Dental and Craniofacial Research
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National Institute of Allergy and Infectious Diseases
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National Center for Advancing Translational Sciences
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National Institute of Environmental Health Sciences
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American Association for the Advancement of Science
586:National Institute on Alcohol Abuse and Alcoholism 328: 140:. He was the deputy director (Intramural) of the 972: 378:Proceedings of the National Academy of Sciences 636:National Institute of General Medical Sciences 955: 707:National Institutes of Health Clinical Center 525: 723:Advanced Research Projects Agency for Health 1011:Members of the National Academy of Medicine 962: 948: 532: 518: 29: 571:National Heart, Lung, and Blood Institute 459: 408: 398: 1056:United States government biography stubs 576:National Human Genome Research Institute 495:NIH Intramural Research Program website 973: 884:National Center for Research Resources 656:National Institute of Nursing Research 257: 255: 253: 220:Gottesman is an elected member of the 513: 234:American Academy of Arts and Sciences 1046:National Institutes of Health people 918: 889:National Institutes of Health Police 869:National Institutes of Health campus 687:John E. Fogarty International Center 273:Office of Research on Women's Health 1016:People from Jersey City, New Jersey 894:Office of Laboratory Animal Welfare 859:United States Public Health Service 733:National Diabetes Education Program 641:National Institute of Mental Health 505:NIH Institutes, Centers and Offices 309:National Institutes of Health (NIH) 250: 13: 230:Association of American Physicians 14: 1067: 1031:21st-century American biochemists 996:20th-century American biochemists 677:Center for Information Technology 488: 1041:21st-century American physicians 1036:20th-century American physicians 922: 626:National Institute on Drug Abuse 262:Pharmacology Conference Speakers 864:Division of Intramural Research 215: 178:NIH Intramural Research Program 16:American biochemist (born 1946) 425: 368: 322: 297: 278: 112:, Boston; Harvard University; 1: 991:Harvard Medical School alumni 907:indicate acting officeholders 542:National Institutes of Health 243: 142:National Institutes of Health 114:National Institutes of Health 1026:American medical researchers 934:. You can help Knowledge by 682:Center for Scientific Review 661:National Library of Medicine 346:10.1016/0092-8674(86)90595-7 294:, NCI, retrieved 2010-02-28. 238:National Academy of Sciences 226:National Academy of Medicine 85:National Academy of Sciences 7: 581:National Institute on Aging 212:and function of a protein. 187: 170:Peter Dent Brigham Hospital 110:Peter Dent Brigham Hospital 10: 1072: 917: 128:(born October 7, 1946, in 902: 844: 746: 715: 669: 561:National Cancer Institute 553: 267:January 16, 2009, at the 180:by pediatric neurologist 151: 146:National Cancer Institute 119: 105: 97: 90: 80: 72: 62: 37: 28: 21: 879:NIH Public Access Policy 791:James Augustine Shannon 702:Vaccine Research Center 461:10.1126/science.1135308 400:10.1073/pnas.84.21.7735 148:(NCI) within the NIH. 130:Jersey City, New Jersey 55:Jersey City, New Jersey 1051:Harvard College alumni 786:William H. Sebrell, Jr 566:National Eye Institute 166:Harvard Medical School 806:Donald S. Fredrickson 728:Visible Human Project 1021:Physician-scientists 206:silent polymorphisms 198:multidrug resistance 126:Michael M. Gottesman 23:Michael M. Gottesman 811:James B. Wyngaarden 452:2007Sci...315..525K 391:1987PNAS...84.7735T 196:(MDR1, ABCB1), the 138:physician-scientist 836:Monica Bertagnolli 290:2010-05-27 at the 210:tertiary structure 67:Harvard University 943: 942: 912: 911: 796:Robert Q. Marston 776:Lewis R. Thompson 761:Milton J. Rosenau 756:Joseph J. Kinyoun 446:(5811): 525–528, 385:(21): 7735–7738, 132:) is an American 123: 122: 92:Scientific career 1063: 964: 957: 950: 926: 919: 821:Harold E. Varmus 766:John F. Anderson 738:BRAIN Initiative 534: 527: 520: 511: 510: 482: 480: 463: 429: 423: 421: 412: 402: 372: 366: 364: 326: 320: 319: 317: 316: 301: 295: 282: 276: 259: 236:(2010), and the 202:Science magazine 51: 47: 45: 33: 19: 18: 1071: 1070: 1066: 1065: 1064: 1062: 1061: 1060: 971: 970: 969: 968: 915: 913: 908: 898: 840: 831:Francis Collins 816:Bernadine Healy 771:George W. McCoy 742: 711: 665: 549: 538: 491: 486: 485: 430: 426: 373: 369: 327: 323: 314: 312: 303: 302: 298: 292:Wayback Machine 283: 279: 269:Wayback Machine 260: 251: 246: 218: 208:can impact the 190: 162:magna cum laude 158:summa cum laude 154: 58: 52: 49: 48:October 7, 1946 43: 41: 24: 17: 12: 11: 5: 1069: 1059: 1058: 1053: 1048: 1043: 1038: 1033: 1028: 1023: 1018: 1013: 1008: 1003: 998: 993: 988: 983: 967: 966: 959: 952: 944: 941: 940: 927: 910: 909: 903: 900: 899: 897: 896: 891: 886: 881: 876: 871: 866: 861: 856: 848: 846: 842: 841: 839: 838: 833: 828: 826:Elias Zerhouni 823: 818: 813: 808: 803: 798: 793: 788: 783: 778: 773: 768: 763: 758: 752: 750: 744: 743: 741: 740: 735: 730: 725: 719: 717: 713: 712: 710: 709: 704: 699: 694: 689: 684: 679: 673: 671: 667: 666: 664: 663: 658: 653: 648: 643: 638: 633: 628: 623: 618: 613: 608: 603: 598: 593: 588: 583: 578: 573: 568: 563: 557: 555: 551: 550: 537: 536: 529: 522: 514: 508: 507: 502: 497: 490: 489:External links 487: 484: 483: 424: 367: 340:(3): 381–389, 321: 296: 277: 248: 247: 245: 242: 217: 214: 194:P-glycoprotein 189: 186: 153: 150: 121: 120: 117: 116: 107: 103: 102: 99: 95: 94: 88: 87: 82: 78: 77: 74: 73:Known for 70: 69: 64: 60: 59: 53: 39: 35: 34: 26: 25: 22: 15: 9: 6: 4: 3: 2: 1068: 1057: 1054: 1052: 1049: 1047: 1044: 1042: 1039: 1037: 1034: 1032: 1029: 1027: 1024: 1022: 1019: 1017: 1014: 1012: 1009: 1007: 1004: 1002: 999: 997: 994: 992: 989: 987: 986:Living people 984: 982: 979: 978: 976: 965: 960: 958: 953: 951: 946: 945: 939: 937: 933: 928: 925: 921: 920: 916: 906: 901: 895: 892: 890: 887: 885: 882: 880: 877: 875: 872: 870: 867: 865: 862: 860: 857: 855: 854: 850: 849: 847: 843: 837: 834: 832: 829: 827: 824: 822: 819: 817: 814: 812: 809: 807: 804: 802: 799: 797: 794: 792: 789: 787: 784: 782: 779: 777: 774: 772: 769: 767: 764: 762: 759: 757: 754: 753: 751: 749: 745: 739: 736: 734: 731: 729: 726: 724: 721: 720: 718: 714: 708: 705: 703: 700: 698: 695: 693: 690: 688: 685: 683: 680: 678: 675: 674: 672: 668: 662: 659: 657: 654: 652: 649: 647: 644: 642: 639: 637: 634: 632: 629: 627: 624: 622: 619: 617: 614: 612: 609: 607: 604: 602: 599: 597: 594: 592: 589: 587: 584: 582: 579: 577: 574: 572: 569: 567: 564: 562: 559: 558: 556: 552: 547: 543: 535: 530: 528: 523: 521: 516: 515: 512: 506: 503: 501: 498: 496: 493: 492: 479: 475: 471: 467: 462: 457: 453: 449: 445: 441: 440: 435: 428: 420: 416: 411: 406: 401: 396: 392: 388: 384: 380: 379: 371: 363: 359: 355: 351: 347: 343: 339: 335: 334: 325: 310: 306: 300: 293: 289: 286: 285:Staff profile 281: 274: 270: 266: 263: 258: 256: 254: 249: 241: 239: 235: 231: 227: 223: 213: 211: 207: 203: 199: 195: 185: 183: 182:Nina F. Schor 179: 175: 171: 167: 163: 159: 156:He graduated 149: 147: 143: 139: 135: 131: 127: 118: 115: 111: 108: 104: 100: 96: 93: 89: 86: 83: 79: 75: 71: 68: 65: 61: 56: 50:(age 77) 40: 36: 32: 27: 20: 936:expanding it 929: 914: 904: 851: 801:Robert Stone 500:NIH homepage 443: 437: 427: 382: 376: 370: 337: 331: 324: 313:. Retrieved 311:. 2022-07-13 308: 299: 280: 232:(2006), the 228:(2003), the 224:(1988), the 219: 216:Distinctions 191: 155: 125: 124: 106:Institutions 101:Biochemistry 91: 981:1946 births 975:Categories 853:NIH Record 781:Rolla Dyer 554:Institutes 315:2022-07-29 244:References 134:biochemist 44:1946-10-07 748:Directors 63:Education 716:Programs 478:15146955 470:17185560 362:20431107 288:Archived 265:Archived 240:(2018). 188:Research 905:Italics 845:Related 670:Centers 448:Bibcode 439:Science 419:2444983 387:Bibcode 354:2876781 476:  468:  417:  410:299375 407:  360:  352:  174:Boston 152:Career 98:Fields 81:Awards 57:, U.S. 540:U.S. 474:S2CID 358:S2CID 204:that 164:from 932:stub 546:list 466:PMID 415:PMID 350:PMID 333:Cell 136:and 38:Born 456:doi 444:315 405:PMC 395:doi 342:doi 172:in 977:: 472:, 464:, 454:, 442:, 436:, 413:, 403:, 393:, 383:84 381:, 356:, 348:, 338:47 336:, 307:. 271:, 252:^ 184:. 46:) 963:e 956:t 949:v 938:. 548:) 544:( 533:e 526:t 519:v 481:. 458:: 450:: 422:. 397:: 389:: 365:. 344:: 318:. 42:(

Index


Jersey City, New Jersey
Harvard University
National Academy of Sciences
Peter Dent Brigham Hospital
National Institutes of Health
Jersey City, New Jersey
biochemist
physician-scientist
National Institutes of Health
National Cancer Institute
summa cum laude
magna cum laude
Harvard Medical School
Peter Dent Brigham Hospital
Boston
NIH Intramural Research Program
Nina F. Schor
P-glycoprotein
multidrug resistance
Science magazine
silent polymorphisms
tertiary structure
American Association for the Advancement of Science
National Academy of Medicine
Association of American Physicians
American Academy of Arts and Sciences
National Academy of Sciences

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