2498:
101:, a molecule that mimics the hydrophilic moiety of lidocaine by way of a positively charged amine, has been found to block the channel when the receptor is open restricting the flow of Na and K ions. 2,6-
82:
of the muscle‐type nicotinic receptor. Since receptor activation occurs as isolated bursts, it has been proposed that the receptors have a very low channel‐opening rate constant when bound to TEA.
1401:
97:, has multiple inhibitory actions on the receptor and analysis of the structure of lidocaine has identified the presence of a hydrophobic aromatic ring and a hydrophilic terminal amine.
131:
is a permanently positively charged species. It can bind to the receptor at different sites in both the open and closed conformations. Both of these local anesthetics enhance nAChR
105:, a molecule that mimics the hydrophobic moiety of lidocaine, has been found to bind the receptor at inter-subunit crevices of the trans-membrane spanning domain thereby causing
425:
Cobo, Raúl; Nikolaeva-Koleva, Magdalena; Alberola-Die, Armando; Fernández-Ballester, Gregorio; González-Ros, José Manuel; Ivorra, Isabel; Morales, Andrés (15 July 2020).
2044:
2480:
1394:
1604:
2475:
493:
Cobo, Raúl; Nikolaeva, Magdalena; Alberola-Die, Armando; Fernández-Ballester, Gregorio; González-Ros, José M.; Ivorra, Isabel; Morales, Andrés (2018-08-08).
1387:
641:
1749:
1729:
739:
1906:
17:
1684:
2344:
1654:
2039:
1479:
1474:
601:
2558:
1609:
1886:
1829:
1794:
1769:
1674:
1499:
1494:
1911:
2184:
634:
2539:
554:"The actions of suxamethonium (succinyldicholine) as an agonist and channel blocker at the nicotinic receptor of frog muscle"
373:"Muscle-Type Nicotinic Receptor Modulation by 2,6-Dimethylaniline, a Molecule Resembling the Hydrophobic Moiety of Lidocaine"
244:
627:
427:"Mechanisms of Blockade of the Muscle-Type Nicotinic Receptor by Benzocaine, a Permanently Uncharged Local Anesthetic"
1421:
1050:
1038:
56:
1410:
1070:
947:
215:
210:
32:
619:
1844:
1440:
1083:
2470:
127:
is a permanently uncharged species that inhibits the receptor by plugging the pore of the opened channel.
2563:
1534:
2513:
2532:
1858:
1584:
1454:
1105:
1062:
132:
106:
905:
2444:
1119:
658:
1574:
1863:
1306:
52:
1379:
609:
495:"Mechanisms Underlying the Strong Inhibition of Muscle-Type Nicotinic Receptors by Tetracaine"
322:"Muscle-Type Nicotinic Receptor Blockade by Diethylamine, the Hydrophilic Moiety of Lidocaine"
2525:
2429:
2378:
2339:
654:
2424:
2289:
2269:
2109:
2054:
1969:
1759:
371:
Alberola-Die A, Fernández-Ballester G, González-Ros JM, Ivorra I, Morales A (2016-11-24).
320:
Alberola-Die A, Fernández-Ballester G, González-Ros JM, Ivorra I, Morales A (2016-02-15).
8:
2439:
2324:
2309:
2244:
1839:
1319:
2359:
2299:
2209:
2134:
2029:
2014:
2004:
1413:
1122:
857:
666:
578:
553:
529:
494:
472:
442:
399:
372:
348:
321:
294:
261:
75:
2449:
2169:
2049:
1929:
583:
534:
516:
476:
464:
456:
404:
353:
299:
281:
262:"Activation and block of mouse muscle-type nicotinic receptors by tetraethylammonium"
240:
1948:
1944:
1872:
178:
2319:
2129:
2024:
1896:
1459:
1435:
1164:
897:
573:
569:
565:
524:
506:
446:
438:
424:
394:
384:
343:
333:
289:
273:
120:
94:
1974:
649:
370:
319:
277:
102:
1876:
1868:
2509:
2154:
1804:
1599:
1544:
731:
683:
1880:
183:
2552:
2497:
2434:
2264:
2234:
2174:
2124:
2119:
2009:
1979:
1925:
1754:
1569:
1504:
1209:
1139:
723:
675:
520:
511:
460:
389:
338:
285:
188:
166:
149:
492:
2505:
2349:
2279:
2274:
2189:
1999:
1989:
1940:
1921:
1719:
1639:
1629:
1327:
538:
468:
426:
408:
357:
303:
198:
98:
587:
2454:
2419:
2399:
2314:
2304:
2259:
2239:
2159:
2089:
2079:
2069:
2064:
2034:
1824:
1819:
1809:
1799:
1744:
1709:
1699:
1694:
1689:
1679:
1619:
1594:
1589:
1509:
650:
193:
451:
2414:
2394:
2354:
2329:
2294:
2284:
2229:
2219:
2214:
2204:
2179:
2144:
2099:
2094:
2074:
2059:
2019:
1984:
1916:
1901:
1891:
1644:
1634:
1579:
1539:
1524:
128:
124:
116:
112:
123:
that have an inhibitory effect on the muscle‐type nicotinic receptor.
2254:
2249:
2224:
2199:
2194:
2164:
2114:
2104:
2084:
1954:
1739:
1734:
1724:
1549:
1529:
1519:
1514:
1469:
161:
90:
64:
2408:
2334:
2149:
2139:
1959:
1714:
1704:
1664:
1659:
1649:
1614:
1564:
1559:
1464:
2404:
2384:
1964:
1935:
1789:
1784:
1779:
1774:
1764:
1668:
1554:
1489:
1484:
1254:
1249:
998:
79:
1994:
1814:
1624:
1409:
1244:
1239:
1234:
1229:
1224:
1219:
1018:
1013:
1008:
1003:
993:
988:
983:
978:
973:
968:
963:
958:
882:
874:
866:
827:
819:
811:
803:
795:
787:
779:
771:
763:
755:
747:
60:
2364:
1362:
1357:
1352:
1347:
1342:
1337:
1332:
1287:
1279:
1214:
1189:
1184:
1179:
1174:
1169:
1158:
1153:
1148:
1143:
1028:
1023:
929:
921:
913:
850:
845:
840:
835:
711:
706:
701:
696:
691:
937:
235:
Rang HP, Dale MM, Ritter JM, Moore PK, et al. (2003).
1422:
1845:
1441:
551:
552:
Marshall CG, Ogden DC, Colquhoun D (September 1990).
239:(5th ed.). Churchill Livingstone. p. 138.
1318:
234:
2550:
260:Akk, Gustav; Steinbach, Joe Henry (2003-08-15).
51:(fetal receptor). These receptors are found in
2340:Trimetaphan camsilate (trimethaphan camsylate)
2533:
2481:Acetylcholine metabolism/transport modulators
1395:
635:
2476:Muscarinic acetylcholine receptor modulators
259:
2540:
2526:
1402:
1388:
642:
628:
109:and restricting the channel from opening.
1427:Tooltip Nicotinic acetylcholine receptors
577:
528:
510:
450:
398:
388:
347:
337:
293:
1970:Candocuronium iodide (chandonium iodide)
57:excitatory postsynaptic potential (EPSP)
594:
14:
2551:
1850:Tooltip negative allosteric modulators
1446:Tooltip positive allosteric modulators
35:consisting of the subunit combination
1383:
623:
420:
418:
2492:
488:
486:
315:
313:
499:Frontiers in Molecular Neuroscience
377:Frontiers in Molecular Neuroscience
326:Frontiers in Molecular Neuroscience
228:
155:
24:
443:10.1016/j.neuroscience.2019.05.043
415:
25:
2575:
2559:Nicotinic acetylcholine receptors
2055:Dimethyltubocurarine (metocurine)
483:
310:
78:is a molecule found to be a weak
2496:
1411:Nicotinic acetylcholine receptor
216:Ganglion type nicotinic receptor
211:Nicotinic acetylcholine receptor
33:nicotinic acetylcholine receptor
2435:Meclofenoxate (centrophenoxine)
1760:Suxethonium (succinyldicholine)
1755:Suxamethonium (succinylcholine)
55:, where activation leads to an
570:10.1113/jphysiol.1990.sp018205
545:
364:
253:
172:
29:muscle-type nicotinic receptor
18:Muscle type nicotinic receptor
13:
1:
2471:Receptor/signaling modulators
2125:Hexamethonium (benzohexonium)
221:
85:
70:
2512:. You can help Knowledge by
278:10.1113/jphysiol.2003.043885
7:
2205:Methorphan (racemethorphan)
1535:Bephenium hydroxynaphthoate
204:
10:
2580:
2491:
1585:Dimethylphenylpiperazinium
143:
138:
107:non-competitive inhibition
2463:
2377:
1838:
1434:
1420:
1305:
1265:
1202:Voltage- and ligand-gated
1200:
1130:
1118:
1096:
946:
896:
722:
674:
665:
659:ligand-gated ion channels
558:The Journal of Physiology
266:The Journal of Physiology
2445:Phosphatidylethanolamine
606:Neurosci.pharm, MBC 3320
512:10.3389/fnmol.2018.00193
390:10.3389/fnmol.2016.00127
339:10.3389/fnmol.2016.00012
76:Tetraethylammonium (TEA)
2225:Morphanol (racemorphan)
2165:Laudexium (laudolissin)
1575:Desformylflustrabromine
948:Nicotinic acetylcholine
53:neuromuscular junctions
59:, mainly by increased
2430:Glycerophosphocholine
655:cell surface receptor
103:Dimethylaniline (DMA)
2425:Dimethylethanolamine
2290:Rapacuronium bromide
2270:Pipecuronium bromide
2110:Gantacurium chloride
2070:Dizocilpine (MK-801)
1655:MEM-63,908 (RG-3487)
1605:Ethoxysebacylcholine
1320:Purinergic receptors
43:(adult receptor) or
2440:Phosphatidylcholine
2325:Threohydrobupropion
2310:Stercuronium iodide
2245:Pancuronium bromide
2564:Biochemistry stubs
2360:Vecuronium bromide
2300:Rocuronium bromide
2210:Methyllycaconitine
2135:Hydroxynorketamine
2030:Dextropropoxyphene
2015:Dehydronorketamine
2005:Dacuronium bromide
1088:β1δε - Muscle type
667:Cys-loop receptors
99:Diethylamine (DEA)
2521:
2520:
2489:
2488:
2450:Phosphorylcholine
2388:
2373:
2372:
2170:Levacetylmethadol
2050:Dihydrochandonium
1930:sodium thiopental
1600:Ethanol (alcohol)
1377:
1376:
1373:
1372:
1301:
1300:
1132:Ligand-gated only
1114:
1113:
272:(Pt 1): 155–168.
246:978-0-443-07145-4
121:local anesthetics
16:(Redirected from
2571:
2542:
2535:
2528:
2500:
2493:
2382:
2320:Thiocolchicoside
2130:Hydroxybupropion
2025:Dextromethorphan
1897:Allopregnanolone
1851:
1847:
1750:Suberyldicholine
1460:6-Chloronicotine
1447:
1443:
1432:
1431:
1428:
1424:
1404:
1397:
1390:
1381:
1380:
1316:
1315:
1128:
1127:
672:
671:
644:
637:
630:
621:
620:
614:
613:
608:. Archived from
598:
592:
591:
581:
549:
543:
542:
532:
514:
490:
481:
480:
454:
422:
413:
412:
402:
392:
368:
362:
361:
351:
341:
317:
308:
307:
297:
257:
251:
250:
232:
156:Partial Agonists
95:local anesthetic
21:
2579:
2578:
2574:
2573:
2572:
2570:
2569:
2568:
2549:
2548:
2547:
2546:
2490:
2485:
2459:
2381:
2369:
1975:Chlorisondamine
1849:
1842:
1834:
1445:
1438:
1426:
1416:
1408:
1378:
1369:
1297:
1291:
1283:
1261:
1196:
1110:
1092:
1087:
1079:- Ganglion type
1078:
1074:
1066:
1058:
1054:
1046:
1042:
942:
933:
925:
917:
909:
892:
886:
878:
870:
861:
831:
823:
815:
807:
799:
791:
783:
775:
767:
759:
751:
743:
735:
718:
687:
661:
648:
618:
617:
602:"Acetylcholine"
600:
599:
595:
550:
546:
491:
484:
423:
416:
369:
365:
318:
311:
258:
254:
247:
233:
229:
224:
207:
175:
158:
146:
141:
133:desensitization
88:
73:
67:permeability.
48:
40:
23:
22:
15:
12:
11:
5:
2577:
2567:
2566:
2561:
2545:
2544:
2537:
2530:
2522:
2519:
2518:
2501:
2487:
2486:
2484:
2483:
2478:
2473:
2468:
2464:
2461:
2460:
2458:
2457:
2452:
2447:
2442:
2437:
2432:
2427:
2422:
2417:
2412:
2402:
2397:
2391:
2389:
2375:
2374:
2371:
2370:
2368:
2367:
2362:
2357:
2352:
2347:
2342:
2337:
2332:
2327:
2322:
2317:
2312:
2307:
2302:
2297:
2292:
2287:
2282:
2277:
2272:
2267:
2262:
2257:
2252:
2247:
2242:
2237:
2232:
2227:
2222:
2217:
2212:
2207:
2202:
2197:
2192:
2187:
2182:
2177:
2172:
2167:
2162:
2157:
2155:Kynurenic acid
2152:
2147:
2142:
2137:
2132:
2127:
2122:
2117:
2112:
2107:
2102:
2097:
2092:
2087:
2082:
2077:
2072:
2067:
2062:
2057:
2052:
2047:
2042:
2037:
2032:
2027:
2022:
2017:
2012:
2007:
2002:
1997:
1992:
1987:
1982:
1977:
1972:
1967:
1962:
1957:
1952:
1949:κ-bungarotoxin
1945:α-bungarotoxin
1938:
1933:
1919:
1914:
1909:
1904:
1899:
1894:
1889:
1884:
1883:, many others)
1873:α-bungarotoxin
1866:
1861:
1855:
1853:
1836:
1835:
1833:
1832:
1827:
1822:
1817:
1812:
1807:
1805:Tribendimidine
1802:
1797:
1792:
1787:
1782:
1777:
1772:
1767:
1762:
1757:
1752:
1747:
1742:
1737:
1732:
1730:Sebacylcholine
1727:
1722:
1717:
1712:
1707:
1702:
1697:
1692:
1687:
1682:
1677:
1672:
1662:
1657:
1652:
1647:
1642:
1637:
1632:
1627:
1622:
1617:
1612:
1607:
1602:
1597:
1592:
1587:
1582:
1577:
1572:
1567:
1562:
1557:
1552:
1547:
1545:Butyrylcholine
1542:
1537:
1532:
1527:
1522:
1517:
1512:
1507:
1502:
1497:
1492:
1487:
1482:
1477:
1472:
1467:
1462:
1457:
1451:
1449:
1429:
1418:
1417:
1407:
1406:
1399:
1392:
1384:
1375:
1374:
1371:
1370:
1368:
1367:
1366:
1365:
1360:
1355:
1350:
1345:
1340:
1335:
1324:
1322:
1313:
1311:gated channels
1303:
1302:
1299:
1298:
1296:
1295:
1294:
1293:
1289:
1285:
1281:
1271:
1269:
1263:
1262:
1260:
1259:
1258:
1257:
1252:
1247:
1242:
1237:
1232:
1227:
1222:
1217:
1206:
1204:
1198:
1197:
1195:
1194:
1193:
1192:
1187:
1182:
1177:
1172:
1162:
1156:
1151:
1146:
1136:
1134:
1125:
1116:
1115:
1112:
1111:
1109:
1108:
1106:Zinc-activated
1102:
1100:
1094:
1093:
1091:
1090:
1085:
1081:
1076:
1072:
1068:
1064:
1060:
1056:
1052:
1048:
1044:
1040:
1032:
1031:
1026:
1021:
1016:
1011:
1006:
1001:
996:
991:
986:
981:
976:
971:
966:
961:
952:
950:
944:
943:
941:
940:
935:
931:
927:
923:
919:
915:
911:
907:
902:
900:
894:
893:
891:
890:
889:
888:
884:
880:
876:
872:
868:
859:
855:
854:
853:
848:
843:
838:
833:
829:
825:
821:
817:
813:
809:
805:
801:
797:
793:
789:
785:
781:
777:
773:
769:
765:
761:
757:
753:
749:
745:
741:
733:
728:
726:
720:
719:
717:
716:
715:
714:
709:
704:
699:
694:
685:
680:
678:
676:5-HT/serotonin
669:
663:
662:
647:
646:
639:
632:
624:
616:
615:
612:on 2007-12-27.
593:
544:
482:
414:
363:
309:
252:
245:
226:
225:
223:
220:
219:
218:
213:
206:
203:
202:
201:
196:
191:
186:
181:
179:α-Bungarotoxin
174:
171:
170:
169:
164:
157:
154:
153:
152:
145:
142:
140:
137:
87:
84:
72:
69:
46:
38:
9:
6:
4:
3:
2:
2576:
2565:
2562:
2560:
2557:
2556:
2554:
2543:
2538:
2536:
2531:
2529:
2524:
2523:
2517:
2515:
2511:
2508:article is a
2507:
2502:
2499:
2495:
2494:
2482:
2479:
2477:
2474:
2472:
2469:
2466:
2465:
2462:
2456:
2453:
2451:
2448:
2446:
2443:
2441:
2438:
2436:
2433:
2431:
2428:
2426:
2423:
2421:
2418:
2416:
2413:
2410:
2406:
2403:
2401:
2398:
2396:
2393:
2392:
2390:
2386:
2380:
2376:
2366:
2363:
2361:
2358:
2356:
2353:
2351:
2348:
2346:
2343:
2341:
2338:
2336:
2333:
2331:
2328:
2326:
2323:
2321:
2318:
2316:
2313:
2311:
2308:
2306:
2303:
2301:
2298:
2296:
2293:
2291:
2288:
2286:
2283:
2281:
2278:
2276:
2273:
2271:
2268:
2266:
2265:Phencyclidine
2263:
2261:
2258:
2256:
2253:
2251:
2248:
2246:
2243:
2241:
2238:
2236:
2235:Nitrous oxide
2233:
2231:
2228:
2226:
2223:
2221:
2218:
2216:
2213:
2211:
2208:
2206:
2203:
2201:
2198:
2196:
2193:
2191:
2188:
2186:
2183:
2181:
2178:
2176:
2175:Levomethadone
2173:
2171:
2168:
2166:
2163:
2161:
2158:
2156:
2153:
2151:
2148:
2146:
2143:
2141:
2138:
2136:
2133:
2131:
2128:
2126:
2123:
2121:
2120:Hexafluronium
2118:
2116:
2113:
2111:
2108:
2106:
2103:
2101:
2098:
2096:
2093:
2091:
2088:
2086:
2083:
2081:
2078:
2076:
2073:
2071:
2068:
2066:
2063:
2061:
2058:
2056:
2053:
2051:
2048:
2046:
2043:
2041:
2038:
2036:
2033:
2031:
2028:
2026:
2023:
2021:
2018:
2016:
2013:
2011:
2010:Decamethonium
2008:
2006:
2003:
2001:
1998:
1996:
1993:
1991:
1988:
1986:
1983:
1981:
1980:Cisatracurium
1978:
1976:
1973:
1971:
1968:
1966:
1963:
1961:
1958:
1956:
1953:
1950:
1946:
1942:
1941:Bungarotoxins
1939:
1937:
1934:
1931:
1927:
1926:pentobarbital
1923:
1920:
1918:
1915:
1913:
1910:
1908:
1905:
1903:
1900:
1898:
1895:
1893:
1890:
1888:
1885:
1882:
1878:
1874:
1870:
1869:α-Neurotoxins
1867:
1865:
1862:
1860:
1857:
1856:
1854:
1848:
1841:
1837:
1831:
1828:
1826:
1823:
1821:
1818:
1816:
1813:
1811:
1808:
1806:
1803:
1801:
1798:
1796:
1793:
1791:
1788:
1786:
1783:
1781:
1778:
1776:
1773:
1771:
1768:
1766:
1763:
1761:
1758:
1756:
1753:
1751:
1748:
1746:
1743:
1741:
1738:
1736:
1733:
1731:
1728:
1726:
1723:
1721:
1718:
1716:
1713:
1711:
1708:
1706:
1703:
1701:
1698:
1696:
1693:
1691:
1688:
1686:
1683:
1681:
1678:
1676:
1673:
1670:
1666:
1663:
1661:
1658:
1656:
1653:
1651:
1648:
1646:
1643:
1641:
1638:
1636:
1633:
1631:
1628:
1626:
1623:
1621:
1618:
1616:
1613:
1611:
1608:
1606:
1603:
1601:
1598:
1596:
1593:
1591:
1588:
1586:
1583:
1581:
1578:
1576:
1573:
1571:
1570:Decamethonium
1568:
1566:
1563:
1561:
1558:
1556:
1553:
1551:
1548:
1546:
1543:
1541:
1538:
1536:
1533:
1531:
1528:
1526:
1523:
1521:
1518:
1516:
1513:
1511:
1508:
1506:
1505:Acetylcholine
1503:
1501:
1498:
1496:
1493:
1491:
1488:
1486:
1483:
1481:
1478:
1476:
1473:
1471:
1468:
1466:
1463:
1461:
1458:
1456:
1453:
1452:
1450:
1444:
1437:
1433:
1430:
1425:
1419:
1415:
1412:
1405:
1400:
1398:
1393:
1391:
1386:
1385:
1382:
1364:
1361:
1359:
1356:
1354:
1351:
1349:
1346:
1344:
1341:
1339:
1336:
1334:
1331:
1330:
1329:
1326:
1325:
1323:
1321:
1317:
1314:
1312:
1308:
1304:
1292:
1286:
1284:
1278:
1277:
1276:
1273:
1272:
1270:
1268:
1264:
1256:
1253:
1251:
1248:
1246:
1243:
1241:
1238:
1236:
1233:
1231:
1228:
1226:
1223:
1221:
1218:
1216:
1213:
1212:
1211:
1208:
1207:
1205:
1203:
1199:
1191:
1188:
1186:
1183:
1181:
1178:
1176:
1173:
1171:
1168:
1167:
1166:
1163:
1160:
1157:
1155:
1152:
1150:
1147:
1145:
1141:
1138:
1137:
1135:
1133:
1129:
1126:
1124:
1121:
1117:
1107:
1104:
1103:
1101:
1099:
1095:
1089:
1082:
1080:
1069:
1067:
1061:
1059:
1049:
1047:
1037:
1034:
1033:
1030:
1027:
1025:
1022:
1020:
1017:
1015:
1012:
1010:
1007:
1005:
1002:
1000:
997:
995:
992:
990:
987:
985:
982:
980:
977:
975:
972:
970:
967:
965:
962:
960:
957:
954:
953:
951:
949:
945:
939:
936:
934:
928:
926:
920:
918:
912:
910:
904:
903:
901:
899:
895:
887:
881:
879:
873:
871:
865:
864:
863:
856:
852:
849:
847:
844:
842:
839:
837:
834:
832:
826:
824:
818:
816:
810:
808:
802:
800:
794:
792:
786:
784:
778:
776:
770:
768:
762:
760:
754:
752:
746:
744:
738:
737:
736:
730:
729:
727:
725:
721:
713:
710:
708:
705:
703:
700:
698:
695:
693:
690:
689:
688:
682:
681:
679:
677:
673:
670:
668:
664:
660:
656:
652:
645:
640:
638:
633:
631:
626:
625:
622:
611:
607:
603:
597:
589:
585:
580:
575:
571:
567:
563:
559:
555:
548:
540:
536:
531:
526:
522:
518:
513:
508:
504:
500:
496:
489:
487:
478:
474:
470:
466:
462:
458:
453:
448:
444:
440:
436:
432:
428:
421:
419:
410:
406:
401:
396:
391:
386:
382:
378:
374:
367:
359:
355:
350:
345:
340:
335:
331:
327:
323:
316:
314:
305:
301:
296:
291:
287:
283:
279:
275:
271:
267:
263:
256:
248:
242:
238:
231:
227:
217:
214:
212:
209:
208:
200:
197:
195:
192:
190:
189:Hexamethonium
187:
185:
182:
180:
177:
176:
168:
167:Suxamethonium
165:
163:
160:
159:
151:
150:Acetylcholine
148:
147:
136:
134:
130:
126:
122:
118:
114:
110:
108:
104:
100:
96:
92:
83:
81:
77:
68:
66:
62:
58:
54:
50:
42:
34:
31:is a type of
30:
19:
2514:expanding it
2506:biochemistry
2503:
2350:Tubocurarine
2280:Promegestone
2275:Progesterone
2190:Mecamylamine
2000:Cyclopropane
1990:Coronaridine
1922:Barbiturates
1907:Anatruxonium
1877:α-cobratoxin
1720:Sazetidine A
1640:JNJ-39393406
1630:Ispronicline
1310:
1274:
1266:
1201:
1131:
1097:
1035:
955:
610:the original
605:
596:
561:
557:
547:
502:
498:
452:10045/107949
434:
431:Neuroscience
430:
380:
376:
366:
329:
325:
269:
265:
255:
237:Pharmacology
236:
230:
199:Tubocurarine
111:
89:
74:
44:
36:
28:
26:
2455:Pirisudanol
2420:Cyprodenate
2400:Adafenoxate
2315:Surugatoxin
2305:Sevoflurane
2260:Pentolinium
2240:Norketamine
2160:Laudanosine
2090:Erythravine
2080:Encenicline
2065:Dipyrandium
2035:Dextrorphan
1881:α-conotoxin
1840:Antagonists
1825:WAY-317,538
1820:Varenicline
1810:Tropisetron
1800:Tebanicline
1745:SSR-180,711
1710:Rivanicline
1700:Pozanicline
1695:PNU-282,987
1690:PNU-120,596
1685:PHA-709,829
1680:PHA-543,613
1620:Galantamine
1595:Epiboxidine
1590:Epibatidine
1510:Altinicline
651:Ion channel
194:Pancuronium
184:α-Conotoxin
173:Antagonists
2553:Categories
2415:Citicoline
2395:Acetyl-coA
2379:Precursors
2355:Vanoxerine
2345:Tropeinium
2330:Toxiferine
2295:Reboxetine
2285:Radafaxine
2230:Neramexane
2220:Mivacurium
2215:Metocurine
2180:Malouetine
2145:Isoflurane
2100:Fazadinium
2095:Esketamine
2075:Doxacurium
2060:Dioscorine
2020:Desflurane
1985:Coclaurine
1917:Atracurium
1902:Amantadine
1892:Alcuronium
1645:Levamisole
1635:Ivermectin
1580:Dianicline
1540:Butinoline
1525:Anatoxin-a
1414:modulators
1123:glutamates
1120:Ionotropic
1036:pentamers:
564:: 155–74.
222:References
129:Tetracaine
125:Benzocaine
117:tetracaine
113:Benzocaine
86:Inhibition
71:Activation
2255:Pentamine
2250:Pempidine
2200:Methadone
2195:Memantine
2115:Halothane
2105:Gallamine
2085:Enflurane
2040:Diadonium
1955:Bupropion
1740:SIB-1553A
1735:SIB-1508Y
1725:SB-206553
1550:Carbachol
1530:AR-R17779
1520:Anatabine
1515:Anabasine
1480:A-867,744
1475:A-582,941
1470:A-366,833
956:monomers:
521:1662-5099
477:171092620
461:1873-7544
437:: 62–79.
286:0022-3751
162:Carbachol
119:are also
91:Lidocaine
2467:See also
2409:lecithin
2385:prodrugs
2335:Tramadol
2185:ME-18-MC
2150:Ketamine
2140:Ibogaine
1960:BW284C51
1715:RJR-2429
1705:Pyrantel
1665:Nicotine
1660:Morantel
1650:Lobeline
1615:EVP-6124
1610:EVP-4473
1565:Cytisine
1560:Cotinine
1465:A-84,543
1436:Agonists
1267:‘Orphan’
539:30135641
469:31158437
409:27932949
358:26912995
304:12824448
205:See also
2405:Choline
1965:BW-A444
1943:(e.g.,
1936:BNC-210
1924:(e.g.,
1887:ABT-126
1871:(e.g.,
1830:XY-4083
1795:TC-6683
1790:TC-5619
1785:TC-5214
1780:TC-2216
1775:TC-1827
1770:TC-1734
1765:TC-1698
1675:NS-1738
1669:tobacco
1555:Choline
1500:ABT-894
1495:ABT-560
1490:ABT-418
1485:ABT-202
1165:Kainate
898:Glycine
588:2133043
579:1181640
530:6092513
505:: 193.
400:5121239
383:: 127.
349:4753328
295:2343137
144:Agonist
139:Ligands
80:agonist
1995:Curare
1912:AQW051
1859:18-MAC
1815:UB-165
1625:GTS-21
1455:5-HIAA
1423:nAChRs
586:
576:
537:
527:
519:
475:
467:
459:
407:
397:
356:
346:
332:: 12.
302:
292:
284:
243:
2504:This
2383:(and
2365:Xenon
1864:18-MC
1843:(and
1439:(and
473:S2CID
2510:stub
2045:DHβE
1846:NAMs
1442:PAMs
1275:GluD
1210:NMDA
1140:AMPA
1098:Zinc
1084:(α1)
1075:(β4)
1071:(α1)
1063:(α7)
1055:(β2)
1051:(α4)
1043:(β4)
1039:(α3)
858:GABA
732:GABA
724:GABA
684:5-HT
584:PMID
535:PMID
517:ISSN
465:PMID
457:ISSN
405:PMID
354:PMID
300:PMID
282:ISSN
241:ISBN
115:and
93:, a
63:and
49:β1δγ
45:(α1)
41:β1δε
37:(α1)
27:The
1328:P2X
1307:ATP
1255:L1B
1250:L1A
999:α10
574:PMC
566:doi
562:428
525:PMC
507:doi
447:hdl
439:doi
435:439
395:PMC
385:doi
344:PMC
334:doi
290:PMC
274:doi
270:551
2555::
1947:,
1928:,
1879:,
1875:,
1245:3B
1240:3A
1235:2D
1230:2C
1225:2B
1220:2A
1019:β4
1014:β3
1009:β2
1004:β1
994:α9
989:α7
984:α6
979:α5
974:α4
969:α3
964:α2
959:α1
862:-ρ
657::
653:,
604:.
582:.
572:.
560:.
556:.
533:.
523:.
515:.
503:11
501:.
497:.
485:^
471:.
463:.
455:.
445:.
433:.
429:.
417:^
403:.
393:.
379:.
375:.
352:.
342:.
328:.
324:.
312:^
298:.
288:.
280:.
268:.
264:.
135:.
61:Na
2541:e
2534:t
2527:v
2516:.
2411:)
2407:(
2387:)
1951:)
1932:)
1852:)
1671:)
1667:(
1448:)
1403:e
1396:t
1389:v
1363:7
1358:6
1353:5
1348:4
1343:3
1338:2
1333:1
1309:-
1290:2
1288:δ
1282:1
1280:δ
1215:1
1190:5
1185:4
1180:3
1175:2
1170:1
1161:)
1159:4
1154:3
1149:2
1144:1
1142:(
1086:2
1077:3
1073:2
1065:5
1057:3
1053:2
1045:3
1041:2
1029:ε
1024:δ
938:β
932:4
930:α
924:3
922:α
916:2
914:α
908:1
906:α
885:3
883:ρ
877:2
875:ρ
869:1
867:ρ
860:A
851:θ
846:π
841:ε
836:δ
830:3
828:γ
822:2
820:γ
814:1
812:γ
806:3
804:β
798:2
796:β
790:1
788:β
782:6
780:α
774:5
772:α
766:4
764:α
758:3
756:α
750:2
748:α
742:1
740:α
734:A
712:E
707:D
702:C
697:B
692:A
686:3
643:e
636:t
629:v
590:.
568::
541:.
509::
479:.
449::
441::
411:.
387::
381:9
360:.
336::
330:9
306:.
276::
249:.
65:K
47:2
39:2
20:)
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