Polio eradication - Knowledge

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limited surveillance and under-vaccinated populations. Moreover, for WPV1—the only type of the virus which is currently circulating following the eradication of WPV2 and WPV3—only 1 in 200 infection cases exhibit symptoms of polio paralysis in non-vaccinated children, and possibly even fewer in vaccinated children. Therefore, even a single case is indicative of an epidemic. According to modeling, it can take four to six months of no reported cases to achieve only a 50% chance of eradication, and one to two years for e.g. 95% chance. Sensitivity of monitoring for circulation can be improved by sampling sewage. In Pakistan in the last couple of years, the number of paralysis cases has dropped relatively faster than the positive environmental samples, which has shown no progress since 2015. The presence of multiple infections with the same strain in the upstream area may not be detectable, so there are some saturation effects when monitoring the number of positive environmental samples. Furthermore, virus may shed beyond the expected duration of several weeks in certain individuals. Contagiousness can not be readily excluded. For a polio virus to be certified as eradicated worldwide, at least three years of good surveillance without cases needs to be achieved, though this period may need to be longer for a strain like WPV3, where a lower proportion of those infected demonstrate symptoms, or if virus-positive environmental samples continue to be reported. Wild poliovirus type

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cVDPV2 outbreaks in Nigeria, the Democratic Republic of Congo, and Somalia continued into 2019 and spread to neighboring countries, while several countries experienced new outbreaks. In addition to eighteen reported paralysis cases in Nigeria, the cVDPV2 outbreaks there spread to Benin, Burkina Faso, Chad, Ghana, Niger, and Togo, while the virus was also detected in environmental samples from Cameroon and Ivory Coast. Somalia's continuing outbreaks caused a half-dozen cases there and in neighboring Ethiopia, with a separate Ethiopia outbreak adding one case. The Democratic Republic of the Congo had numerous new and continuing outbreaks, producing more than 80 cases, while multiple new cVDPV2 outbreaks in Angola and the Central African Republic resulted in more than a hundred cases. Individual new outbreaks of cVDPV2 also caused more than a dozen paralysis cases each in Pakistan and the Philippines, while smaller outbreaks struck Chad, China, and Zambia. A separate cVDPV1 outbreak in the Philippines also caused cases in Malaysia, where cVDPV2 of Filipino origin was also detected in environmental samples, while additional cVDPV1 outbreaks caused six cases in Myanmar and one case in Yemen.

3293:, and on poor quality surveillance extant in Southeast Africa 684 confirmed cVDPV2 cases were seen across twenty countries during 2022, in addition to 189 cases of cVDPV1 and one case of cVDPV3 in Israel. The first case since 2013 was reported in the United States, tied to cVDPV2 strains found in Israel and the United Kingdom. In Burundi and the Democratic Republic of the Congo, two outbreaks of cVDPV2 that caused a combined seven cases were identified as having a link to the nOPV2 vaccine, the first outbreaks with ties to nOPV2 after its initial deployment in 2021; according to an assessment reported by the GPEI, an estimated 30–40 additional outbreaks of cVDPV2 would have occurred from March 2021 – March 2023 without the nOPV2 rollout. Vaccine-derived viral strains were also detected in environmental samples from a number of additional countries without diagnosed cases. From February to May, traces of cVDPV2 were discovered in sewage in London, United Kingdom. This led the United Kingdom to declare a "national incident". However, authorities have said that the risk to the general public is "extremely low", and no cases have been reported. 1046: 568:

carry the disease, allowing polio to spread widely before cases are seen. In 2000, using new screening techniques for the molecular characterization of outbreak viral strains, it was discovered that some of the outbreaks were actually caused by circulating vaccine-derived poliovirus, following mutations or recombinations in the attenuated strain used for the oral polio vaccine. This discovery altered the strategy for the discontinuation of vaccination following polio eradication, necessitating an eventual switch to the more expensive and logistically more problematic inactivated polio vaccine, as continued use of the oral inactivated virus would continue to produce such revertant infection-causing strains. The risk of vaccine-derived polio will persist long after the switch to inactivated vaccine, as a small number of

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false narrative in both nations, blaming the other for the presence and spread of polio in their own country. Environmental sampling in Pakistan showed the virus' presence in eight urban areas, a setback officials attributed primarily to vaccine refusal. Opponents to vaccination in Pakistan launched a series of attacks in April that left a vaccinator and two security men dead, while false rumors and hoax videos reporting vaccine toxicity also disrupted vaccination efforts there. Wild poliovirus of Pakistani origin also spread to Iran where it was detected in several environmental samples. Overall, the eradication efforts in Pakistan and Afghanistan have been characterized as having become a "horror show", undermined by "public suspicion, political infighting, mismanagement and security problems".

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least in part by politicization of vaccination and bad governance during the pandemic, may result in a general pattern of undervaccination, including for polio. In Pakistan, a contributing factor to the resurgence of wild virus cases in the country has been threats of violence both from those with anti-vaccine sentiment and from religious extremists. A vaccination worker was assassinated in March 2022, and a vaccinator and two accompanying police officers providing security for a door-to-door vaccination campaign were murdered in June. However, the situation had improved compared to previous years as the government and law-enforcement increased their focus. By October 2022, endemic transmission was restricted to seven districts in southern

581:, Dr. Hussain A. Gezari, the WHO's special envoy on global polio eradication and primary healthcare, gave his views on obstacles to eradication. He said that the biggest hurdle preventing Pakistan from becoming polio-free was holding district health officials properly accountable—in national eradication campaigns officials had hired their own relatives, even young children. Gezari asked, "How do you expect a seven-year-old thumb-sucking kid to implement a polio campaign of the government?" and added that, in spite of this, "the first national campaign was initiated by your government in 1994 and that year Pakistan reported 25,000 polio cases, and the number was just 198 last year, which clearly shows that the programme is working." 1913:, recognizing that this would adversely affect its efforts at eradicating polio. All vaccination efforts, both routine and targeted, were postponed for several months, with staff reassigned to COVID-19 control. Subsequent statistical analysis indicated that the COVID pandemic resulted in decreases of more than 30% globally in both AFP and environmental surveillance, with only 23 of 43 priority countries meeting their surveillance targets for 2020. Additional challenges were a conspiracy theory circulating on social media claiming that the polio vaccine contained coronavirus, and moves by President Donald Trump of the United States to cut funding for the World Health Organization. 471:

contact immunity. However, under conditions of long-term circulation in undervaccinated populations, the virus can accumulate mutations that reverse the attenuation and result in vaccine virus strains that themselves cause polio. As a result of such circulating vaccine-derived poliovirus (cVDPV) strains, polio outbreaks have periodically recurred in regions that have long been free of the wild virus, but where vaccination rates have fallen. Oral vaccines can also give rise to persistent infection in immunodeficient individuals, with the virus eventually mutating into a more virulent immunodeficiency-associated vaccine-derived poliovirus (iVDPV). In particular, the type

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lineages of WPV1 seen in 2015 had been interrupted by September 2017, though at least two genetic clusters remain. In spite of a significant drop in detected cases in Pakistan, there was an increase in the percentage of environmental samples that test positive for the polio virus, suggesting gaps in identification of infected individuals. In the third country where polio remained endemic, Nigeria, there were no cases, though as few as 7% of infants were fully vaccinated in some districts. An April 2017 spill at a vaccine production facility in the Netherlands only resulted in one asymptomatic WPV2 infection, despite release into the sewer system.

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Essential Facilities (PEFs) across 24 countries where work on poliovirus can be carried out. These facilities are currently involved in producing materials to assist the eradication initiative, and perform crucial research which may prevent future outbreaks. After certification, these facilities retain the equipment and materials to continue vaccine production in the event of deliberate or accidental release. Work on Poliovirus outside of the PEFs will be prohibited, and stocks in laboratories that are not designated as PEFs must either be transferred to a PEF or destroyed.

312: 396: 442: 370:) contains trivalent fully inactivated virus, administered by injection. This vaccine cannot induce VAPP nor do cVDPV strains arise from it, but it likewise cannot induce contact immunity and thus must be administered to every individual. Added to this are greater logistical challenges. Though a single dose is sufficient for protection, administration requires medically trained vaccinators armed with single-use needles and syringes. Taken together, these factors result in substantially higher delivery costs. Original protocols involved 458: 1369:, that the vaccine caused sterility in girls. This resulted in the suspension of immunization efforts in the state, causing a dramatic rise in polio rates in the already endemic country. On 30 June 2004, the WHO announced that after a 10-month ban on polio vaccinations, Kano had pledged to restart the campaign in early July. During the ban the virus spread across Nigeria and into 12 neighboring countries that had previously been polio-free. By 2006, this ban would be blamed for 1,500 children being paralyzed and had cost $ 450 1859:

environmental samples. In Afghanistan different strains were largely responsible for the cases in the northeast and south of the country. In Nigeria, the third country classified as having endemic transmission, security concerns continued to limit access to some areas of the country, though migration and novel vaccination approaches would reduce the number of unreached children. The nation passed two full years without a detected wild-virus case, though elimination of WPV transmission could not be confirmed.

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governmental authorities. In Nigeria this has taken the form of 'block rejection' of vaccination that is only resolved when state officials agree to repair or improve schools and health-care facilities, pave roads or install electricity. There have been several instances of threatened boycotts by health workers in Pakistan over payment disputes. Some governments have been accused of withholding vaccination or the necessary accompanying infrastructure from regions where opposition to their rule is high.

1497:) were reported to have endemic polio. Cases in other countries are attributed to importation. A total of 1,997 cases worldwide were reported in 2006; of these the majority (1,869 cases) occurred in countries with endemic polio. Nigeria accounted for the majority of cases (1,122 cases) but India reported more than ten times more cases in 2006 than in 2005 (676 cases, or 30% of worldwide cases). Pakistan and Afghanistan reported 40 and 31 cases respectively in 2006. Polio re-surfaced in 636:(forbidden) in Islam, concern that vaccine production may have involved a prohibited taking of animal life, or a resistance to interfering with disease processes perceived to be divinely-directed. Concerns were addressed through extensive outreach, directed both toward the communities involved and respected clerical bodies, as well as promoting local ownership of the eradication campaign in each region. In early 2012, some parents refused to get their children vaccinated in 40: 4000: 3312: 2600: 1940: 1784: 1645: 1385: 2577:

but the virus continued to be detected in environmental samples through December, and was present in most provinces of the country during the year. The case in Malawi, the country's first in almost three decades and the first in Africa in five years, was seen as a significant setback to the eradication effort. Based on similarity to a strain last detected in Pakistan in 2019, it is thought that WPV1 has been circulating undetected in the country for some time.

1875:, Kenya. This virus, along with newly detected cVDPV3, caused twelve total cases in the country, including one patient infected by both strains. The large number of children residing in areas inaccessible to health workers represent a particular risk for undetected cVDPV outbreaks. A cVDPV2 outbreak in Mozambique resulted in a single case. Response to the Syrian cVDPV2 outbreak continued into 2018, and virus transmission was successfully interrupted. In 1653: 2581:

and the first half of 2021 attributed them to 38 distinct emergences, representing a mix of novel strains and previously detected strains that continued to circulate, while several previously circulating strains were no longer found. 14 cases of cVDPV1 were identified in Madagascar and 3 in Yemen. No cases of cVDPV3 were observed, though it was detected in environmental samples from China, Israel, and its adjacent occupied territories.

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two with OPV2 proved insufficient: not only did they continue, but the vaccination efforts gave rise to a novel cVDPV2 outbreak. The country experienced a total of 20 cases in 2018. Two separate cVDPV2 outbreaks in northern Nigeria produced 34 cases, as well as giving rise to 10 cases in the neighboring Niger. In Somalia, cVDPV2 continued to circulate, causing several polio cases and detected in environmental samples from as far as

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after extensive assessments of the certifications of National Polio Certification Commissions (NCCs) and confirmation that at least 95% of Africa's population had been immunised. WHO Director-General Tedros Adhanom called it a "great day... but not the end of polio", as there remain major continuing outbreaks of vaccine-derived poliovirus in West Africa and Ethiopia in addition to wild cases in Afghanistan and Pakistan.

1465:, and the virus strain was suspected to be the same as the one that has caused outbreaks in Nigeria. New public fears over vaccine safety, which were unfounded, impeded vaccination efforts in Indonesia. In summer 2005, the WHO, UNICEF and the Indonesian government made new efforts to lay the fears to rest, recruiting celebrities and religious leaders in a publicity campaign to promote vaccination. 4565: 4553: 180:" poliovirus (WPV), and the much more prevalent mutated oral vaccine strains, known as circulating vaccine-derived poliovirus (cVDPV) or variant poliovirus. Vaccines against each of the three wild strains of polio have given rise to strains of cVDPV, with cVDPV2 being most prominent. cVDPV caused 524 confirmed paralytic polio cases worldwide in 2023, and was detected in 32 countries. 506:

in the Global Polio Laboratory Network. Since rates of non-polio AFP are expected to be constant and large compared to the number of polio cases, the frequency of non-polio AFP reported in a population is indicative of the effectiveness of surveillance, as is the proportion of AFP patients from whom high-quality stool samples are collected and tested, with a target of at least 80%.

493:. Eradication efforts will eventually require all oral vaccination to be discontinued in favor of the use of injectable vaccines. These vaccines are more expensive and more difficult to deliver, and they lack the ability to induce contact immunity because they contain only killed virus, but they likewise are incapable of giving rise to vaccine-derived viral strains. 667:, the InterAction Alliance, a union of about 200 U.S.-based non-government organizations, deplored the actions of the CIA in using a vaccination campaign as a cover. Pakistan reported the world's highest number of polio cases (198), in 2011. and more than 60 polio vaccination workers were killed between December 2012 and April 2014. In May 2014, CIA director 3981:, after no cases for over a year, raised concerns about the vaccination campaign quality in Pakistan. The report found it was highly likely that the goal of interrupting wild poliovirus transmission in 2023 would be missed and it was certain that ending transmission of vaccine-derived poliovirus will not be possible this year. 1724:, sparking a major vaccination push there. The strain spread to Israel, where there was widespread environmental detection, but like Egypt, no paralysis cases. It had more severe consequences when it spread to neighboring Syria, with the total number of cases eventually reaching 35, the first outbreak there since 1999. 1509:

the southern states and resumed immunisation in the north, where Muslim clerics led a boycott of vaccination in late 2003. Local governments and clerics allowed vaccinations to resume on the condition that the vaccines be manufactured in Indonesia, a majority Muslim country, and not in the United States.

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immunity threshold for poliovirus eradication ranges from approximately 75% in wealthy high-hygiene populations to 97% in poorer environments. If routine immunization were to be stopped, the number of unvaccinated, susceptible individuals would soon exceed the capability of herd immunity to protect them.

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Certification of wild poliovirus eradication requires three consecutive years without case reports, in the presence of reliable disease surveillance networks. Beginning at certification of WPV eradication, the post-certification strategy will come into effect, with program priorities shifting towards

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There were 33 reported WPV1 paralysis cases with an onset of paralysis in 2018 – 21 in Afghanistan and 12 in Pakistan. Polio in Pakistan resurged in the latter part of the year, due in part to the rates of parental refusal for vaccination increasing, with wild poliovirus detected in 20% of the year's

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In 2017 there were 22 reported WPV1 polio cases with onset of paralysis in 2017, down from 37 in 2016. Eight of the cases were in Pakistan and 14 in Afghanistan, where genetic typing showed repeated introduction from Pakistan as well as local transmission. In Pakistan, transmission of several genetic

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Because cVDPV2 strains continued to arise from trivalent oral vaccine that included attenuated PV2, during 2016 this vaccine was replaced with a bivalent version lacking WPV2 as well as trivalent injected inactivated vaccine that cannot lead to cVDPV cases. This was expected to prevent new strains of

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The WPV2 virus was declared eradicated in September 2015 as it had not been detected in circulation since 1999, and WPV3 was declared eradicated in October 2019, having last been detected in 2012. However, both types persist as circulating vaccine-derived strains, the product of years of evolution of

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3 case of polio worldwide had its onset 11 November 2012 in Nigeria; the last wild case outside Nigeria was in April 2012 in Pakistan, and its absence from sewage monitoring in Pakistan suggests that active transmission of this strain has ceased there. A total of 416 wild-virus cases were reported in

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In 2007, there were 1,315 cases of poliomyelitis reported worldwide. Over 60% of cases (874) occurred in India. In Nigeria, the number of polio cases fell dramatically, from 1,122 cases reported in 2006 to 285 cases in 2007. Officials credit the drop in new infections to improved political control in

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A country is regarded as polio-free or non-endemic if no cases have been detected for a year. However, it is still possible for polio to circulate under these circumstances, as was the case for Nigeria, where a particular strain of virus resurfaced after five years in 2016. This can be due to chance,

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response seen from the vaccine. In Nigeria, the most critical barriers identified were management issues, in particular the highly variable importance ascribed to polio by different authorities at the local government level, although funding issues, community perceptions of vaccine safety, inadequate

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Monitoring for AFP aims at identifying outbreaks of polio by screening patients displaying symptoms consistent with, but not exclusive to, severe poliovirus infection. Stool samples are collected from children presenting with AFP and evaluated for the presence of poliovirus by accredited laboratories

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In theory, if the right tools were available, it would be possible to eradicate all infectious diseases that reside only in a human host. In reality, there are distinct biological features of the organisms and technical factors of dealing with them that make their potential eradicability more or less

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agreed to allow United Nations healthcare workers to carry out door-to-door vaccination nationwide for the first time in three years, including a commitment to allowing women to participate in the effort, and to provide safety guarantees to eradication staff. Pakistan's lone case dated from January,

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Laos was declared free of cVDPV1 in March 2017, but three distinct cVDPV2 outbreaks occurred in the Democratic Republic of the Congo, one of them of recent origin, the other two having circulated undetected for more than a year. Together they caused 20 cases by year's end. In Syria, a large outbreak

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has been viewed as a projection of the power of western nations. Refusal of vaccination came to be viewed as resistance to western expansionism, and when the contamination rumours led the Nigerian Supreme Council for Sharia to call for a region-wide boycott of polio vaccination, polio cases in the

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million doses administered. The live virus can circulate in under-vaccinated populations (circulating vaccine-derived poliovirus, cVDPV) and over time can revert to a neurovirulent form causing paralytic polio. Until recent times, a trivalent OPV containing all three virus strains was used, but with

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to the virus. Because of its route of administration, it induces an immunization of the intestinal mucosa that protects against subsequent infection, though multiple doses are necessary to achieve effective prophylaxis. Attenuated poliovirus derived from the oral polio vaccine is excreted, infecting

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On very rare occasions, if a population is seriously under-immunized, there are enough susceptible children for the excreted vaccine-derived polioviruses to begin circulating in the community. If the vaccine-virus is able to circulate for a prolonged period of time uninterrupted, it can mutate and,

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The residual effects of the COVID-19 pandemic continued to be a cause for concern, due to an increased risk of undetected outbreaks due to COVID's interference with routine health care, disease detection, and childhood vaccinations, as well as a concern that an increased fear of vaccines, caused at

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In 2022, there were 30 confirmed cases of WPV1 reported to WHO, with two and 20 cases in Pakistan and Afghanistan respectively, while eight non-endemic cases were recorded in Mozambique, the first cases in the country since 1992. The Mozambique cases derived from the strain of Pakistani origin that

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2021 saw a partial recovery from the challenges to monitoring brought on by the COVID pandemic, with 74% of high-priority countries meeting surveillance targets, an improvement of over 20% from the previous year. March 2021 also saw the first use of the modified nOPV2 vaccine in selected countries,

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Cases caused by vaccine-derived poliovirus were reported in seven countries in 2018, with over 100 total cases, representing nine strains of cVDPV. In the Democratic Republic of the Congo, one of the outbreaks of cVDPV2 first detected in 2017 caused no additional cases, but suppression of the other

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Environmental surveillance is used to supplement AFP surveillance. This entails the routine testing of sewage samples for the presence of virus, which not only allows the effectiveness of vaccination efforts to be evaluated in countries with active transmission, but also allows the detection of new

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to infect another host is reduced; the cycle of transmission is interrupted, and the pathogen cannot reproduce and dies out. This concept, called community immunity or herd immunity, is important to disease eradication, because it means that it is not necessary to inoculate 100% of the population—a

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While IPV does not itself induce mucosal immunity, it has been shown to boost the mucosal immunity from OPV, and the WHO now favors a combined protocol. It is recommended that vulnerable children receive a dose of OPV at birth, then beginning at the age of six weeks a 'primary series' consisting of

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2 OPV in regions with documented cVDPV2 circulation. A novel OPV2 vaccine (nOPV2) genetically modified to reduce the likelihood of disease-causing activating mutations was granted emergency licencing in 2021, and subsequently full licensure in December 2023. Genetically stabilsed vaccines targeting

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Expanded environmental surveillance to detect the presence of poliovirus in communities. Sewage samples are collected at regular and random sites and tested in laboratories for the presence of WPV or cVDPV. Since most polio infections are asymptomatic, transmission can occur in spite of the absence

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Where possible, the number of facilities conducting operations with poliovirus is to be reduced significantly; and the use of wild poliovirus is to be abandoned altogether in favour of genetically stabilized attenuated strains where possible. As of May 2021, there are 74 designated Poliovirus

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In 2021, reported cVDPV2 cases declined to 685 across 22 countries, over half occurring in Nigeria. The virus was also found in environmental samples or in those from symptom-free people in several additional African and Asian nations without reported cases. An analysis of cVDPV2 strains from 2020

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In 2019 there were 176 WPV1 paralysis cases detected: 29 in Afghanistan and 147 in Pakistan. In particular, in Pakistan the number of cases was surging and cross-border migration played a role in polio transmission between the two countries. While itself problematic, this also fostered a dangerous

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The total number of wild-virus cases reported in 2012 was 223, lower than any previous year. These were limited to five countries—Nigeria, Pakistan, Afghanistan, Chad, and Niger—of which all except Nigeria had fewer cases than in 2011. Several additional countries, Chad, the Democratic Republic of

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In 2008, 18 countries reported cases and the total number of cases was 1,651. Of these, 1,505 occurred in the four endemic countries and 146 elsewhere. The largest numbers were in Nigeria (798 cases) and India (559 cases): these two countries combined had 82.2 percent of all cases. Outside endemic

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One factor contributing to the continued circulation of polio immunization programs has been opposition to vaccination in some countries. In one country, Pakistan, "more than 200 polio team workers" have been killed (team members include not only vaccinators but police and security personnel) from

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Two additional challenges are found in unobserved polio transmission and in vaccine-derived poliovirus. First, most individuals infected with poliovirus are asymptomatic or exhibit minor symptoms, with fewer than 1% of infections leading to paralysis, and most infected people are unaware that they

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Herd immunity is an important supplement to vaccination. According to the concept of herd immunity, the population for whom the vaccine fails is still protected by the immunity of those around them, and it can only be achieved when vaccination levels are high. It is estimated that the minimum herd

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IPV, fIPV) has been found to be effective, lowering costs and also allowing for more convenient and cost-effective delivery systems. The use of IPV results in serum immunity, but no intestinal immunity arises. As a consequence, vaccinated individuals are protected from contracting polio, but their

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Nigeria was removed from the list of countries with endemic wild poliovirus in June 2020, four years after the last recorded case in the Northern State of Borno in 2016. Two months later, the World Health Organization declared the African continent free of wild poliovirus. This certification came

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In addition to the WPV resurgence in Pakistan and Afghanistan, 2019 saw a resurgence of cVDPV, with 378 cases. The majority of cases were caused by cVDPV2 strains that were able to arise or spread as a consequence of the withdrawal of the PV2 strain from the standard vaccination regimen. Previous

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In 2014, there were 359 reported cases of wild poliomyelitis, spread over twelve countries. Pakistan had the most with 306, an increase from 93 in 2013, which was blamed on Al Qaeda and Taliban militants preventing aid workers from vaccinating children in rural regions of the country. On 27 March

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According to figures updated in April 2012, the WHO reported that there were 1,352 cases of wild polio across 20 countries in 2010. Reported cases of polio were down 95% in Nigeria (to a historic low of 21 cases) and 94% in India (to a historic low of 42 cases) compared to the previous year, with

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In 2009, a total of 1,604 cases were reported across 23 countries. Four endemic countries accounted for 1,256 of these, with the remaining 348 in 19 sub-Saharan countries with imported cases or re-established transmission. Once again, the largest numbers were in India (741) and Nigeria (388). All

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billion, 6-year cooperative plan (called the 2013–18 Polio Eradication and Endgame Strategic Plan) to eradicate polio from its last reservoirs. The plan called for mass immunization campaigns in the three remaining endemic countries, and also dictated a switch to inactivated virus injections, to

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Over 1000 cases caused by both continuing and novel outbreaks of cVDPV2 were reported in 2020 across twenty-four countries, with 31 additional cases of cVDPV1, and environmental detections in several additional countries with no diagnosed polio cases. While in the past cVDPV outbreaks tended to

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Polio vaccination efforts have also faced resistance in another form. The priority placed on vaccination by national authorities has turned it into a bargaining chip, with communities and interest groups resisting vaccination, not due to direct opposition, but to leverage other concessions from

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An independent evaluation of obstacles to polio eradication requested by the WHO and conducted in 2009 considered the major obstacles in detail by country. In Afghanistan and Pakistan, the researchers concluded that the most significant barrier was insecurity, but that managing human resources,

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While vaccination has played an instrumental role in the reduction of polio cases worldwide, the use of attenuated virus in the oral vaccine carries with it an inherent risk. The oral vaccine is a powerful tool in fighting polio in part because of its person-to-person transmission and resulting

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In the third remaining country in which polio was classified as endemic, Nigeria, wild poliovirus has not been detected since October 2016, and levels of AFP surveillance are sufficient, even in security-compromised regions, to suggest transmission of WPV may have been interrupted. Global WPV3

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Among the greatest obstacles to global polio eradication are the lack of basic health infrastructure, which limits vaccine distribution and delivery, the crippling effects of civil war and internal strife, and the sometimes oppositional stance that marginalized communities take against what is

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in unvaccinated individuals, and thus amplifying the effects of the doses delivered. The oral administration does not require special medical equipment or training. Taken together, these advantages have made it the favored vaccine of many countries, and it has long been preferred by the global

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In 2016 there were 37 reported WPV1 cases, half as many as in 2015, with the majority of the cases in Pakistan and Afghanistan. A small number of additional cases in Nigeria, caused by WPV1, were viewed as a setback, the first being detected there in almost two years, yet the virus had been

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against polio vaccination. Religious boycotts based on contamination concerns have not been limited to the Muslim world. In 2015, after claiming that a tetanus vaccine contained a contraceptive, a group of Kenyan Catholic bishops called on their followers to boycott a planned round of polio

415:. There is no animal reservoir for poliovirus, and the transmission cycle of polio is from one infected person to another person susceptible to the disease, usually through the fecal-oral route. If the vast majority of the population is immune to a particular agent, the ability of that 501:

A global program of surveillance for the presence of polio and the poliovirus plays a critical role in assessment of eradication and in outbreak detection and response. Two distinct methods are used in tandem: acute flaccid paralysis (AFP) surveillance and environmental surveillance.

1852:, and also spreading to neighboring districts saw 74 confirmed cases from a viral strain that had circulated undetected for about two years. Circulation of multiple genetic lines of cVDPV2 was also detected in Banadir province, Somalia, but no infected individuals were identified. 564:, the key issues identified were underdeveloped health systems and low routine vaccine coverage, although the low level of resources committed to Angola and South Sudan for the purpose of curtailing the spread of polio and climatic factors was also identified as playing a role. 3963:, with only a handful of cases in Indonesia, Yemen, and Israel being the exception. cVDPV1 is now concentrated in three countries, 105 cases in the Democratic Republic of the Congo, 24 in Madagascar and four in Mozambique. No cVDPV3 virus has been detected for two years now. 1353:

In 2002, an outbreak of polio occurred in India. The number of planned polio vaccination campaigns had recently been reduced, and populations in northern India, particularly from the Islamic background, engaged in mass resistance to immunization. At this time, the Indian state

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potentially leading to a large outbreak, if the virus reappears there. In Pakistan, they estimate that the long-standing and intractable poliovirus circulation in most of the traditional endemic reservoirs has been eliminated. However, a positive environmental probe in

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On 25 September 2015, the WHO declared that Nigeria was no longer considered endemic for wild polio virus, with no reported case of wild polio virus having been reported since 24 July 2014. A WPV1 strain not seen in five years resurfaced in Nigeria the following year.

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province. All but one wild polio generic cluster remains in Afghanistan in a much improved immunity (>90%) of the population. Levels of access in the country are the best they have been since 2018. However, a large pool of unvaccinated children remain in the

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intestinal mucosa may still be infected and serve as a reservoir for the excretion of live virus. For this reason, IPV is ineffective at halting ongoing outbreaks of WPV or cVDPV, but it has become the vaccine of choice for industrialized, polio-free countries.

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outbreak preparedness and containment of existing virus material rather than circulating disease. Vaccination for WPV1 will cease one year following eradication certification, and eradication of vaccine-derived poliovirus is then targeted for 2030.

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In 2011, 650 WPV cases were reported across sixteen countries: the four endemic countries—Pakistan, Afghanistan, Nigeria, and India—as well as twelve others. Polio transmission recurred in Angola, Chad and the Democratic Republic of the Congo.

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As of 23 September 2024, there have been 36 reported cases of WPV1 with nineteen from Afghanistan and seventeen from Pakistan. Additionally, 340 positive environmental samples have been collected in Pakistan and 74 in Afghanistan.

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cVDPV2 from arising and allow eventual cessation of WPV2 vaccination. The resulting global use of the injectable vaccine caused shortages, and led the WHO in April 2017 to recommend general use of the fIPV vaccination protocol, involving

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country increased more than five-fold between 2002 and 2006, with the uncontrolled virus then spreading across Africa and globally. In Afghanistan and Pakistan, fears that the vaccine contained contraceptives were one reason given by the

644:(FATA) but religious refusals in the rest of the country had "decreased manifold". Even with the express support of political leaders, polio workers or their accompanying security guards have been kidnapped, beaten, or assassinated. 1468:

In the United States on 29 September 2005, the Minnesota Department of Health identified the first occurrence of vaccine-derived poliovirus (VDPV) transmission in the United States since OPV was discontinued in 2000. The poliovirus

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Vaccine-derived cases continue to circulate, particularly in the African and Eastern Mediterranean WHO regions. Concern is focused on Ukraine, where cVDPV had been detected in fall 2021, vaccination efforts were halted due to the

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likely. Three indicators, however, are considered of primary importance in determining the likelihood of successful eradication: that effective interventional tools are available to interrupt transmission of the agent, such as a

4516:. In addition 12 African countries have had positive environmental samples of cVDPV2 but no confirmed cases: Algeria, Cote D'Ivoire, Egypt, Equatorial Guinea, Gambia, Kenya, Senegal, Sierra Leone, Sudan, Uganda and Zimbabwe. 11501: 11617: 1069:

began using the oral vaccine in a series of nationwide polio campaigns. The early success of these mass vaccination campaigns suggested that polioviruses could be globally eradicated. The Pan American Health Organization

270:

Active surveillance for poliovirus through reporting and laboratory testing of all cases of acute flaccid paralysis. Acute flaccid paralysis (AFP) is a clinical manifestation of poliomyelitis characterized by weakness or

488:

2 (nOPV2) that has been genetically stabilized to make it less prone to give rise to circulating vaccine-derived strains received full licensure in December 2023, with similar vaccines targeting types 1 and 3 undergoing

475:

2 strain seems prone to reversions, so in 2016 the eradication effort abandoned the trivalent oral vaccine containing attenuated strains of all three virus types and replaced it with a bivalent oral vaccine lacking the

7512: 3966:

The Independent Monitoring Board of the GPEI in its September 2023 Report mentioned a continued, geographically restricted, endemic transmission in the east of Afghanistan and in the southern districts of Pakistan's

1780:. With the addition of this region, the proportion of world population living in polio-free regions reached 80%. The last case of wild polio in the South-East Asia Region was reported in India on 13 January 2011. 1342:

million children (almost one-tenth the world's population) had received some two billion doses of oral polio vaccine. The World Health Organization announced that Europe was polio-free on 21 June 2002, in the

11087: 3277:

caused two confirmed cases in Malawi in 2021. The cases in Pakistan were the first seen in the country in 15 months, though the virus had been detected in environmental samples during the intervening period.

11966: 1628:) and the Russian Federation, with the most recent case from this region being reported from Russia 25 September. These were the first cases in the WHO European region since 2002. The Republic of the Congo ( 348:

The primary disadvantage of OPV derives from its inherent nature. As an attenuated but active virus, it can induce vaccine-associated paralytic poliomyelitis (VAPP) in approximately one individual per every

7442: 11308: 11186: 1457:, countries that had been declared polio-free since before 2000, each reported hundreds of cases—probably imported from Nigeria. On 5 May 2005, news reports broke that a new case of polio was diagnosed in 11028: 11216: 9568: 596:"targeted killing and terrorism" while working on polio campaigns, (the killers motivated by the belief, spread by "radical clerics", that the vaccine is part of "a Western plot to sterilize Muslims"). 12167: 527:

political pressures, the movement of large populations between and within both countries, and inadequately resourced health facilities also posed problems, as did technical issues with the vaccine. In

6891: 11159: 10650: 1832:. There was also a cVDPV1 outbreak in Laos, while new strains of cVDPV2 arose separately in Nigeria's Borno and Sekoto states, and in the Quetta area of Pakistan, collectively causing five cases. 7103: 5637: 1855:

WHO's Strategic Advisory Group of Experts on Immunization recommended that cVDPV2 suppression be prioritized over targeting WPV1, and according to protocol OPV2 is restricted to this purpose.

1501:

after nearly six years of absence with 18 new cases reported. "Our country is not safe, as neighbours India and Pakistan are not polio free", declared Health Minister ASM Matiur Rahman. (See:

13744: 11367: 9961: 7385: 1690:

2013, almost double the previous year. Of these, cases in endemic countries dropped from 197 to 160, while those in non-endemic countries jumped from 5 to 256. This was due to outbreaks in

8378: 9309: 7869: 10923: 1791:

During 2015, 74 cases of wild poliomyelitis were reported worldwide, 54 in Pakistan and 20 in Afghanistan. There were 32 circulating vaccine-derived poliovirus (cVDPV) cases in 2015.

1632:) saw an outbreak with 441 cases (30% of the global total). At least 179 deaths were associated with this outbreak, which is believed to have been an importation from the ongoing type 12138: 10119: 8705: 8658: 1362:.) However, by 2004, India had adopted strategies to increase ownership of polio vaccinations in marginalized populations, and the immunity gap in vulnerable groups rapidly closed. 10389: 11730: 11609: 6963: 11646: 9542: 10995: 12198: 7065: 5907: 11334: 10700: 9640: 7264:... for each case ..., the community is further threatened by another 2,000 to 3,000 contagious carriers ... rendering even a single documented case indicative of an epidemic 420:

goal that is often logistically very difficult—to achieve the desired result. If the number of susceptible individuals can be reduced to a sufficiently small number through

11715: 9048: 7722: 607:, rumours arose in the Muslim world that immunization campaigns were using intentionally-contaminated vaccines to sterilize local Muslim populations or to infect them with 9278: 7471: 523:

of live (attenuated) vaccines in extremely hot or remote areas. The oral polio vaccine must be kept at 2 to 8 °C (36 to 46 °F) for vaccination to be successful.

10755: 3956:

Twelve cases of WPV1 have been reported in 2023, six in Afghanistan and Pakistan each. Additionally, 187 positive environmental samples were reported in those countries.

13987: 12521: 9215: 7537: 4757: 13615: 11061: 10096: 9513: 9116: 7415: 143:. IPV, being inactivated, does not carry these risks, but does not induce contact immunity. IPV is more costly and the logistics of its delivery are more challenging. 9436: 6846: 1799:

the attenuated "live" virus (which makes up the oral vaccine) as it transmits from the vaccinated to the unvaccinated and circulates in an under-immunized community.

9477: 9378: 9342: 5528: 7438: 230:, be available to detect infections that can lead to transmission of the disease; and that humans are required for the life-cycle of the agent, which has no other 11300: 11182: 9773: 13780: 10454: 6996: 387:

three OPV doses at least four weeks apart, along with one dose of IPV after 14 weeks. This combined IPV/OPV approach has also been used in outbreak suppression.

12107: 12010: 11128: 11018: 10422: 11208: 9579: 8195: 12163: 11277: 6719: 13977: 10873: 8046: 5190: 8984: 1381:

have complicated WHO's polio eradication goal. In 2004, almost two-thirds of all the polio cases in the world occurred in Nigeria (760 out of 1,170 total).

12311: 10791: 256:, supplementary immunization campaigns, and surveillance of possible outbreaks. Several key strategies have been outlined for stopping polio transmission: 11151: 1416:

In May 2004, the first case of the polio outbreak in Sudan was detected. The reemergence of polio led to stepped up vaccination campaigns. In the city of

10646: 7092: 6096: 1713:

was reported, the first in Somalia since 2007. By October, over 170 cases had been reported in the country, with more cases in neighboring Kenya and the

10320: 7287: 6780: 5405: 12796: 11538: 10962: 5633: 4587: 1205: 1057:

Following the widespread use of poliovirus vaccine in the mid-1950s, the incidence of poliomyelitis declined rapidly in many industrialized countries.

127:

polio vaccine (IPV), which is injected. OPV is less expensive and easier to administer, and can spread immunity beyond the person vaccinated, creating

12411: 12047: 9179: 510:

outbreaks in countries without known transmission. In 2018, the GPEI conducted environmental surveillance in 44 countries, 24 of which are in Africa.

12765: 11155: 8848: 7311:"The role of supplementary environmental surveillance to complement acute flaccid paralysis surveillance for wild poliovirus in Pakistan - 2011-2013" 552:

also played a role. In those countries where international spread from endemic countries had resulted in the reestablishment of transmission, namely

9945: 7369: 161:

3 (WPV3) is last known to have caused polio in 2012, and was declared eradicated in 2019. All wild-virus cases since that date have been due to type

11357: 8134:

Yamazaki S, Toraya H (2001). "(General News) Major Milestone reached in Global Polio Eradication: Western Pacific Region is certified Polio-Free".

12289: 9673: 8891:

Likewise, in Kenya, two cases in Garissa County were reported in 2006, 19 cases in Turkana County in 2009, and one case in Rongo district in 2011.

8594: 8491: 8417: 8392: 8251: 12514: 8719: 8669: 8343: 7021: 5307:

Nathanson N, Martin JR (December 1979). "The epidemiology of poliomyelitis: enigmas surrounding its appearance, epidemicity, and disappearance".

5036:"Global Disease Elimination and Eradication as Public Health Strategies. Proceedings of a conference. Atlanta, Georgia, USA. 23-25 February 1998" 1061:

became the first country in the world to scientifically demonstrate nationwide eradication of poliomyelitis in 1960. In 1962—just one year after

9301: 4839: 13892: 13658: 13560: 13278: 12221: 6645: 1373:

million for emergency activities. In addition to the rumors of sterility and the ban by Nigeria's Kano state, civil war and internal strife in

11586: 11238: 9707: 6029: 5148: 671:

prohibited his agency both from using vaccinations to cover operations and from testing samples collected by authentic vaccination campaigns.

213:

As reduction of the worldwide incidence of poliomyelitis to zero as a result of deliberate efforts, and requiring no further control measures.

131:. It has been the predominant vaccine used. However, under conditions of long-term vaccine virus circulation in under-vaccinated populations, 11921: 7845: 6122: 5115: 627:

vaccination. This did not have a major effect on vaccination rates, and dialog along with vaccine testing forestalled further boycott calls.

153:

transmission of wild poliovirus, with its last reported case in 2016. Of the three strains of WPV, the last recorded wild case caused by type

11809: 10899: 9798: 7819: 7184:"Modeling undetected live poliovirus circulation after apparent interruption of transmission: implications for surveillance and vaccination" 4869: 12869: 12360: 12130: 10290: 10123: 9406: 4592: 4541:

By 2022 all stocks of WPV2 had been transferred to PEFs and full containment is in effect. All other strains are in a transitionary status.

267:

Organization of "national immunization days" to provide supplementary doses of oral polio vaccine to all children less than five years old.

9610: 13578: 13470: 12031: 10725: 10375: 1208:(USAID)—launched its effort to support national eradication efforts at the grassroots level. The CORE Group commenced this initiative in 1045: 656: 12328: 11988: 11810:"In new setback for eradication campaign, poliovirus from Pakistan shows up in Africa: Health officials hope to squash outbreak quickly" 10345: 4627: 13750: 13421: 12507: 9729: 8813: 8759: 7964: 6953: 1118: 85: 11642: 9538: 7938: 611:. In Nigeria these rumours fit in with a longstanding suspicion of modern biomedicine, which since its introduction during the era of 176:

are the only two countries where the disease is still classified as endemic. Recent polio cases arise from two sources, the original "

13774: 10984: 9556:

over the course of 12-18 months, reacquire neurovirulence. These viruses are called circulating vaccine-derived polioviruses (cVDPV).

6152: 4696: 1616:

little change in Afghanistan (from 38 to 25 cases) and an increase in cases in Pakistan (from 89 to 144 cases). An acute outbreak in

17: 12190: 11944: 9870: 8844:"Preventing Importation of Poliovirus in the Horn of Africa: The Success of the Cross-Border Health Initiative in Kenya and Somalia" 8458: 8221: 8101: 7057: 5899: 5461: 4657: 1736:

2014, the WHO announced the eradication of poliomyelitis in the South-East Asia Region, in which the WHO includes eleven countries:

1144:

On 20 August 1994, the Americas were certified as polio-free. This achievement was a milestone in efforts to eradicate the disease.

13714: 13622: 13542: 13374: 11330: 10689: 10197: 9632: 6350: 1879:, a cVDPV1 strain arose, causing twenty-six polio cases across nine provinces, while a single diagnosed cVDPV1 case in neighboring 335:

per dose in 2024) and its availability has bolstered efforts to eradicate polio. The vaccine confers long-term, possibly lifelong,

135:

can reactivate the virus to produce a polio-inducing strain, while OPV can also, in rare circumstances, induce polio or persistent

13690: 7670: 6749: 6587:"Did the call for boycott by the Catholic bishops affect the polio vaccination coverage in Kenya in 2015? A cross-sectional study" 363:

poliovirus types 1 and 3 are in development, with the intention that these will eventually completely replace the Sabin vaccines.

13720: 13284: 12780: 9247: 9138: 9040: 7968: 7711: 358:

2 this was phased out in 2016 and replaced with bivalent vaccine containing just types 1 and 3, supplemented with monovalent type

12736: 12246: 12104:"New York State Department of Health and Rockland County Department of Health Alert the Public to A Case of Polio In the County" 9270: 7464: 5488:"Intradermal Administration of Fractional Doses of Inactivated Poliovirus Vaccine: A Dose-Sparing Option for Polio Immunization" 659:

in order to confirm the genetic identity of the children living there, and by implication his own presence, leading directly to

13684: 13068: 10041:"Response to a wild poliovirus type 2 (WPV2)-shedding event following accidental exposure to WPV2, the Netherlands, April 2017" 8636: 8572: 7501: 12272: 9205: 7248: 299:

of polio-related AFP cases, and such monitoring helps to evaluate the degree to which virus continues to circulate in an area.

13409: 13314: 13242: 13187: 9106: 8804: 8750: 7813: 7545: 7407: 5109: 5058: 4761: 600: 11752: 11050: 10088: 9502: 9080: 8169: 7846:"[Global eradication of poliomyelitis. On the 80th anniversary of the founding of the National Institute of Health]" 6836: 4732: 2569:

2 poliovirus without the frequent spawning of cVDPV2 seen with the original OPV2. Full rollout was not expected until 2023.

13664: 13608: 13433: 13380: 12806: 12346: 10528: 9444: 8537: 7848:[Global eradication of poliomyelitis. On the 80th anniversary of the founding of the National Institute of Health] 2561:

In 2021, there were just six confirmed cases of wild poliovirus — one in Pakistan, four in Afghanistan, and one in Malawi.

13439: 9466: 9367: 9331: 5487: 13548: 13344: 13338: 13320: 13218: 13138: 12939: 12770: 11057: 10785: 10092: 9769: 9669: 9573: 9509: 9473: 9374: 9338: 9017: 8937: 8908: 8713: 8665: 8599: 8386: 8071: 7541: 7506: 7281: 7130:"A spatial model of Wild Poliovirus Type 1 in Kano State, Nigeria: calibration and assessment of elimination probability" 6157: 5903: 5401: 4574: 3959:

There have been 391 confirmed cases of cVDPV2 reported to the WHO in 2023, across 22 countries, nineteen of which lie in

1122: 1090: 641: 93: 8014: 7571: 6311: 5009: 630:

Other religion-inspired refusals arise from concern over whether the virus contains pig-derived products, and hence are

264:(OPV) in the first year of life in developing and endemic countries, and routine immunization with OPV or IPV elsewhere. 13602: 13362: 13248: 12530: 9762: 6813: 5825: 5602: 5369: 97: 11883: 10447: 8980: 6986: 1521:

in July 2007, Turai Yar'Adua urged parents to vaccinate their children and stressed the safety of oral polio vaccine.

331:

poliovirus. OPV is delivered as oral drops or infused into sugar cubes. It is highly effective and inexpensive (about

13785: 13756: 13646: 13590: 13506: 12103: 11120: 10414: 1359: 8199: 13898: 13702: 13572: 13536: 13524: 13427: 13350: 12889: 11269: 10448:

The Art of Survival: The Polio Virus Continues to Exploit Human Frailties. 17th Independent Monitoring Board Report

8039: 6709: 4129: 3395: 3290: 2721: 2127: 1601: 1529: 10862: 6772: 5691: 5171: 1620:

gave rise to 460 cases (34% of the global total), and was associated with a further 18 cases across Central Asia (

13768: 13762: 13732: 13652: 13554: 13494: 13457: 13445: 13356: 13181: 12967: 12801: 12775: 10234:"Update on Vaccine-Derived Poliovirus Outbreaks - Democratic Republic of the Congo and Horn of Africa, 2017-2018" 6070: 1732:

avoid the risk of the vaccine-derived outbreaks that occasionally occur from use of the live-virus oral vaccine.

10780: 9009: 13880: 13868: 13862: 13850: 13844: 13838: 13726: 13670: 13640: 13628: 8425: 5931:"Managing the risk of circulating vaccine-derived poliovirus during the endgame: oral poliovirus vaccine needs" 4607: 572:

continue to produce active virus for years (or even decades) after their initial exposure to the oral vaccine.

12629: 10312: 6931: 6428:"The History and Current Killings of Polio Vaccinators in Pakistan: A Need for Targeted Surveillance Strategy" 6100: 5555:"Impact of inactivated poliovirus vaccine on mucosal immunity: implications for the polio eradication endgame" 5342: 5228: 1151:

Campaign to eliminate polio. The current campaign involves annual vaccination of all children under age five.

484:

2 vaccine (mOPV2) was to be used only to target existing cVDPV2 outbreaks. A novel oral vaccine targeting type

13596: 13512: 13114: 12580: 11689: 7276: 7242: 5397: 1240: 12884: 11534: 10952: 9169: 8931:

Hui-Ming Luo, Yong Zhang, Xin-Qi Wang, Wen-Zhou Yu, Ning Wen, Dong-Mei Yan, et al. (21 November 2013).

8335: 7465:

Global Commission for the Certification of Poliomyelitis Eradication (GCC) Report from the Sixteenth Meeting

13566: 13386: 13272: 13266: 13175: 11769: 10147:"Vaccine-Derived Poliovirus Outbreaks and Events - Three Provinces, Democratic Republic of the Congo, 2017" 6991: 5172:

Polio environmental surveillance expansion plan: global expansion plan under the endgame strategy 2013-2018

4530:

As of 2023, WPV2 and WPV3 are certified as eradicated, while certification of WPV1 is expected for 2026/7.

5429:"Fractional-Dose Inactivated Poliovirus Vaccine Immunization Campaign - Telangana State, India, June 2016" 13950: 13944: 13738: 13708: 13518: 13488: 13368: 13144: 1685:

the Congo, Somalia, and Yemen, saw outbreaks of circulating vaccine-derived polio. The last reported type

1517:, made the eradication of polio one of her priorities. Attending the launch of immunization campaigns in 648: 519:

perceived as a potentially hostile intervention by outsiders. Another challenge has been maintaining the

379: 223: 12634: 8843: 8481: 8262: 5255:"Long-Term Immunogenicity of Inactivated and Oral Polio Vaccines: An Italian Retrospective Cohort Study" 13530: 13199: 13169: 11304: 11270:"Polio makes a comeback in the Philippines 19 years after the country was declared free of the disease" 10815:"Strategic Response to an Outbreak of Circulating Vaccine-Derived Poliovirus Type 2 - Syria, 2017-2018" 9662: 8605: 7032: 668: 660: 1443:

recorded just 66 cases in 2005, down from 135 cases reported in 2004, 225 in 2003, and 1,600 in 2002.

13972: 13254: 12917: 12864: 12714: 11242: 10989: 10869: 10729: 10647:"Nigeria not lowering guards against Polio, two years after last detection of cases in the Northeast" 10383: 10349: 10201: 9802: 9734: 9440: 9410: 9142: 8421: 8256: 8225: 8105: 8075: 7666: 7182:

Kalkowska DA, Duintjer Tebbens RJ, Pallansch MA, Cochi SL, Wassilak SG, Thompson KM (February 2015).

7097: 7061: 7026: 6635: 6126: 5606: 5178: 5093: 4835: 4661: 1106: 73: 6529:"Listening to the rumours: what the northern Nigeria polio vaccine boycott can tell us ten years on" 2572:

Despite previous resistance to eradication efforts, after their takeover of Afghanistan in 2021 the

688:

2 was certified eradicated in 2015, the last case having been detected in 1999. Wild poliovirus type

13922: 13904: 12896: 12816: 12671: 11578: 11246: 9699: 6130: 5988: 5140: 3539: 2888: 1573: 531:, the major challenge appeared to be the high efficiency of transmission within the populations of 227: 11389:

Zomahoun DJ, Burman AL, Snider CJ, Chauvin C, Gardner T, Lickness JS, et al. (January 2021).

9806: 8746:"Evaluating Surveillance Indicators Supporting the Global Polio Eradication Initiative, 2011–2012" 5084: 4786:

Geiger K, Stehling-Ariza T, Bigouette JP, Bennett SD, Burns CC, Quddus A, et al. (May 2024).

4504:

168 cases of cVDPV2 cases have been found across sixteen different countries, all of which are in

302:

Targeted "mop-up" campaigns once poliovirus transmission is limited to specific geographical foci.

283:) among children less than fifteen years old. Other pathogenic agents can also cause AFP, such as 13928: 13832: 13826: 13193: 13126: 13108: 12932: 12879: 12649: 12557: 11502:"Polio was almost eradicated. Then came the coronavirus. Then came a threat from President Trump" 9946:"'What the hell is going on?' Polio cases are vanishing in Pakistan, yet the virus won't go away" 7800: 7370:"'What the hell is going on?' Polio cases are vanishing in Pakistan, yet the virus won't go away" 4861: 4635: 1845: 1821: 1528:

in over 20 years. Other countries with significant numbers of wild polio virus cases include the

1435:. Eradication efforts in the Indian sub-continent met with a large measure of success. Using the 412: 371: 249: 207: 10282: 9414: 7470:(Report). Global Commission for the Certification of Poliomyelitis Eradication. September 2017. 5486:

Okayasu H, Sein C, Chang Blanc D, Gonzalez AR, Zehrung D, Jarrahian C, et al. (July 2017).

1909:

In March 2020, the GPEI announced polio eradication resources were being redeployed against the

13874: 13820: 13225: 13211: 13028: 12600: 10733: 9602: 8903: 6892:"Polio is back in Nigeria, and the next vaccination campaign may have a surprising consequence" 1817: 1347: 520: 375: 150: 12379: 11834:

Alleman MM, Jorba J, Henderson E, Diop OM, Shaukat S, Traoré MA, et al. (December 2021).

11183:"Campaign to stamp out polio in remaining hot spots has become 'a horror story', report warns" 10376:"Summary of the April 2017 meeting of the Strategic Advisory Group of Experts on Immunization" 10353: 10145:

Alleman MM, Chitale R, Burns CC, Iber J, Dybdahl-Sissoko N, Chen Q, et al. (March 2018).

9895:

Elhamidi Y, Mahamud A, Safdar M, Al Tamimi W, Jorba J, Mbaeyi C, et al. (November 2017).

1636:

1 outbreak in Angola (33 cases in 2010) and the Democratic Republic of the Congo (100 cases).

1201:

2 poliovirus occurred in India. This type of poliovirus was subsequently declared eradicated.

13856: 13814: 13392: 10813:

Mbaeyi C, Wadood ZM, Moran T, Ather F, Stehling-Ariza T, Nikulin J, et al. (June 2018).

9740: 9603:"As hopes for polio eradication rise, the endgame gets complicated, and a vaccine runs short" 6342: 3187: 2449: 1502: 604: 252:

of poliovirus. Stopping polio transmission has been pursued through a combination of routine

12666: 12435:

Bigouette JP, Wilkinson AL, Tallis G, Burns CC, Wassilak SG, Vertefeuille JF (August 2021).

7934: 5169: 5082: 4519:

Six cVDPV1 cases have been detected in the Democratic Republic of the Congo and Mozambique.

1133:

million toward immunising all of the world's children against the disease. The last case of

1125:(GPEI), with the goal of eradicating polio by the year 2000. The initiative was inspired by 192:

As elimination of the occurrence of poliomyelitis even in the absence of human intervention.

13992: 13463: 13260: 13205: 13120: 12676: 9828:

Martinez M, Shukla H, Nikulin J, Wadood MZ, Hadler S, Mbaeyi C, et al. (August 2017).

9636: 8143: 8102:"WHO European Region celebrates three polio-free years: certification within reach in 2002" 7322: 4952: 1236: 1126: 1110: 569: 89: 11967:"Pakistan's fight against polio threatened by extremist violence, anti-vaccine sentiments" 10056: 7799:

Centers for Disease Control and Prevention (2015). Hamborsky J, Kroger A, Wolfe S (eds.).

6163: 5679: 5427:

Bahl S, Verma H, Bhatnagar P, Haldar P, Satapathy A, Kumar KN, et al. (August 2016).

4688: 4665: 1086: 395: 311: 8: 13696: 13326: 13091: 13044: 13038: 12610: 11506: 11092: 10205: 9829: 8842:

Ahmed Arale, Mercy Lutukai, Somane Mohamed, Lydia Bologna, Katherine V. Stamidis (2019).

8799: 8745: 8454: 8229: 8109: 7309:

Cowger TL, Burns CC, Sharif S, Gary HE, Iber J, Henderson E, et al. (25 July 2017).

6958: 6896: 5428: 1428: 124: 43:

A child receives oral polio vaccine during a 2002 campaign to immunize children in India.

12247:"U.K. declares 'national incident' after 'vaccine derived' polio strain found in sewage" 12011:"Meeting of the Technical Advisory Group (TAG) on Poliomyelitis Eradication in Pakistan" 10479:

Hsu C, Mahamud A, Safdar M, Nikulin J, Jorba J, Bullard K, et al. (November 2018).

8147: 7326: 6452: 6427: 5987:

Patel JC, Diop OM, Gardner T, Chavan S, Jorba J, Wassilak SG, et al. (April 2019).

5801: 5766: 4956: 4812: 4787: 1862: 1553: 1544:

other countries had less than one hundred cases: Pakistan had 89 cases, Afghanistan 38,

1420:, 78,654 children were immunized and 20,432 more in southern Sudan (Yirol and Chelkou). 1378: 13677: 13584: 13332: 13163: 13132: 12925: 12463: 12436: 11860: 11835: 11770:"GPEI Statement on WPV1 in Malawi: Wild poliovirus type 1 detected in Lilongwe, Malawi" 11716:"Independent experts advise move to next use phase for novel oral polio vaccine type 2" 11477: 11452: 11430: 11417: 11390: 10957: 10915: 10839: 10814: 10623: 10598: 10571: 10546: 10505: 10480: 10258: 10233: 10232:

Mbaeyi C, Alleman MM, Ehrhardt D, Wiesen E, Burns CC, Liu H, et al. (March 2019).

10171: 10146: 10065: 10040: 10012: 9987: 9921: 9896: 9857: 9210: 9146: 9111: 8870: 8768: 8312: 8285: 7662: 7622: 7345: 7310: 7210: 7183: 7156: 7129: 6741: 6611: 6586: 6553: 6528: 6501: 6476: 6403: 6378: 6298: 6213: 6186: 6016: 5957: 5930: 5876: 5851: 5742: 5717: 5579: 5554: 5515: 5320: 5281: 5254: 4920: 4895: 4505: 3968: 3960: 3282: 637: 336: 328: 120: 11051:"How to Cut a Long Story Short (Sixteenth Report of the Independent Monitoring Board)" 9237: 8932: 7960: 7770: 6585:

Njeru I, Ajack Y, Muitherero C, Onyango D, Musyoka J, Onuekusi I, et al. (2016).

5253:

Larocca AM, Bianchi FP, Bozzi A, Tafuri S, Stefanizzi P, Germinario CA (August 2022).

1891:

eradication was certified in October 2019, the virus not having been seen since 2012.

13934: 13415: 13080: 13017: 12828: 12499: 12468: 12164:"GPEI Statement on cVDPV2 detections in Burundi and Democratic Republic of the Congo" 11865: 11482: 11434: 11422: 11362: 10948: 10919: 10844: 10628: 10597:

Adamu US, Archer WR, Braka F, Damisa E, Siddique A, Baig S, et al. (July 2019).

10576: 10510: 10263: 10176: 10070: 10017: 9986:

Bolu O, Nnadi C, Damisa E, Braka F, Siddique A, Archer WR, et al. (March 2018).

9926: 9862: 9201: 9102: 8954: 8875: 8817: 8773: 8529: 8515:"Poliovirus infections in four unvaccinated children--Minnesota, August-October 2005" 8317: 8006: 7908: 7904: 7861: 7809: 7627: 7350: 7215: 7161: 6690: 6616: 6558: 6506: 6457: 6408: 6303: 6259: 6218: 6021: 5962: 5881: 5806: 5788: 5747: 5683: 5584: 5520: 5453: 5324: 5286: 5105: 5050: 5001: 4968: 4925: 4817: 4602: 4597: 3973: 1910: 1514: 1510: 1474: 1187: 441: 234: 81: 11836:"Update on Vaccine-Derived Poliovirus Outbreaks - Worldwide, January 2020-June 2021" 11610:"Africa Declares Wild Polio Is Wiped Out — Yet It Persists In Vaccine-Derived Cases" 8628: 8562: 7602: 6868: 1720:

Routine sewage monitoring in 2012 had detected a WPV1 strain of Pakistani origin in

647:

Skepticism in the Muslim world was exacerbated when it was learned that in 2011 the

13916: 13050: 13005: 12956: 12834: 12731: 12458: 12448: 12085: 11855: 11847: 11731:"Taliban will allow a national polio vaccination campaign in Afghanistan, says WHO" 11560: 11472: 11464: 11412: 11402: 10907: 10834: 10826: 10618: 10610: 10566: 10558: 10500: 10492: 10481:"Progress Toward Poliomyelitis Eradication - Pakistan, January 2017-September 2018" 10253: 10245: 10166: 10158: 10060: 10052: 10007: 9999: 9953: 9916: 9908: 9897:"Progress Toward Poliomyelitis Eradication - Pakistan, January 2016-September 2017" 9852: 9844: 8946: 8865: 8857: 8841: 8763: 8307: 8297: 8151: 7900: 7617: 7377: 7340: 7330: 7234: 7205: 7195: 7151: 7141: 6680: 6606: 6602: 6598: 6548: 6540: 6496: 6488: 6447: 6439: 6398: 6390: 6293: 6249: 6208: 6198: 6011: 6003: 5952: 5942: 5871: 5863: 5796: 5778: 5737: 5729: 5675: 5574: 5566: 5510: 5502: 5443: 5316: 5276: 5266: 5182: 5097: 4960: 4915: 4907: 4807: 4799: 4788:"Progress Toward Poliomyelitis Eradication - Worldwide, January 2022-December 2023" 1906:

140 cases of WPV1 paralysis were reported in 2020, all in Afghanistan or Pakistan.

1876: 1849: 576: 457: 341: 128: 10198:"Circulating vaccine-derived poliovirus type 2 – Democratic Republic of the Congo" 5570: 5035: 4964: 1921:

remain localized, significant international spread of these strains was observed.

13500: 13056: 13011: 12984: 12644: 11783: 10120:"Polio update: Two cVDPV2 outbreaks reported in Democratic Republic of the Congo" 9830:"Progress Toward Poliomyelitis Eradication - Afghanistan, January 2016-June 2017" 9242: 9174: 9075: 9070: 8632: 8567: 8302: 8173: 7335: 6808: 6745: 6667:

Ahmed A, Lee KS, Bukhsh A, Al-Worafi YM, Sarker MM, Ming LC, et al. (2018).

6544: 5852:"Engineering the Live-Attenuated Polio Vaccine to Prevent Reversion to Virulence" 5850:

Yeh MT, Bujaki E, Dolan PT, Smith M, Wahid R, Konz J, et al. (13 May 2020).

4896:"Eradication versus control: the economics of global infectious disease policies" 4724: 4692: 4569: 1524:

In July 2007, a student traveling from Pakistan imported the first polio case to

1075: 590: 280: 203:, such that the infectious agent no longer exists in nature or in the laboratory. 140: 12661: 12073: 11453:"Surveillance to Track Progress Toward Polio Eradication - Worldwide, 2020-2021" 11358:"'We have no choice.' Pandemic forces polio eradication group to halt campaigns" 10547:"Progress Toward Poliomyelitis Eradication - Afghanistan, January 2018-May 2019" 8797: 8743: 8514: 8512: 7989: 5989:"Surveillance to Track Progress Toward Polio Eradication - Worldwide, 2017-2018" 5033: 246: 13982: 12992: 12841: 12576: 10286: 9606: 7891:

Hinman AR (June 1984). "Landmark perspective: Mass vaccination against polio".

6685: 6668: 6187:"Ending Use of Oral Poliovirus Vaccine - A Difficult Move in the Polio Endgame" 5867: 5634:"Combination of oral, injectable polio vaccine used for first time in outbreak" 4580: 4557: 4509: 1699: 1691: 1058: 544: 490: 12656: 10545:

Martinez M, Shukla H, Nikulin J, Mbaeyi C, Jorba J, Ehrhardt D (August 2019).

8079: 7200: 7146: 6636:"Polio cases jump in Pakistan as clerics declare vaccination an American plot" 6443: 5947: 5783: 5733: 1652: 1085:

Much of the work towards eradication was documented by Brazilian photographer

13966: 13910: 13062: 12048:"Ukraine War and Other Crises Threaten Polio Eradication, Health Experts Say" 11407: 7991: 6803: 6279:"Update on Vaccine-Derived Polioviruses - Worldwide, January 2014-March 2015" 6278: 5792: 5610: 5271: 5170:

Global Polio Eradication Initiative, World Health Organization (April 2015).

4986: 3233: 2357: 1714: 1458: 1355: 1175: 1159: 536: 404: 320: 261: 116: 69: 31: 12488: 11451:

Wilkinson AL, Diop OM, Jorba J, Gardner T, Snider CJ, Ahmed J (April 2022).

11152:"Four new polio cases in Pakistan as study tackles partial-dose vaccination" 10911: 10599:"Progress Toward Poliomyelitis Eradication - Nigeria, January 2018-May 2019" 9988:"Progress Toward Poliomyelitis Eradication - Nigeria, January-December 2017" 9957: 8930: 7579: 7381: 7058:"The poliovirus transmission in Lao People's Democratic Republic has ceased" 5506: 1358:

accounted for nearly two-thirds of total worldwide cases reported. (See the

12472: 12453: 11869: 11851: 11486: 11468: 11426: 11023: 10900:"Surging cases have dashed all hope that polio might be eradicated in 2019" 10848: 10830: 10632: 10614: 10580: 10562: 10514: 10496: 10267: 10249: 10180: 10162: 10074: 10021: 10003: 9930: 9912: 9866: 9848: 9730:"Circulating vaccine-derived poliovirus – Lao People's Democratic Republic" 8958: 8933:"Identification and Control of a Poliomyelitis Outbreak in Xinjiang, China" 8879: 8821: 8777: 8533: 8486: 8321: 8155: 7865: 7631: 7354: 7219: 7165: 6841: 6714: 6694: 6640: 6620: 6562: 6510: 6461: 6412: 6394: 6307: 6263: 6222: 6025: 6007: 5966: 5885: 5810: 5751: 5588: 5524: 5457: 5448: 5290: 5054: 4972: 4929: 4821: 4803: 3752: 2403: 2288: 1625: 1585: 1565: 1518: 1062: 1050: 664: 407:. For polio to occur in a population, there must be an infecting organism ( 324: 253: 136: 8950: 8861: 8010: 7912: 7798: 6492: 5687: 5005: 1065:'s oral polio vaccine (OPV) was licensed in most industrialized countries— 692:

3 has not been detected since 2012, and was certified eradicated in 2019.

39: 13886: 13074: 12901: 12821: 12333:

World Health Organization - Regional Office for the Eastern Mediterranean

11898: 7093:"Government of Nigeria reports 2 wild polio cases, first since July 2014" 6254: 6237: 6203: 5328: 4987:"Recommendations of the International Task Force for Disease Eradication" 4513: 4204: 4037: 3775: 3608: 3349: 2698: 2242: 1977: 1777: 1745: 1629: 1494: 1436: 1182:

became the last case of polio reported in Europe. In 1997, Mum Chanty of

1148: 1049:

Kindergarten children receive a very early oral polio vaccine in 1960 in

652: 612: 561: 421: 284: 276: 169: 112: 12089: 11121:"Pakistan's anti-vaccination movement leads to string of deadly attacks" 8252:"WHO Director-General calls India 'number 1' polio eradication priority" 6837:"CIA tactics to trap Bin Laden linked with polio crisis, say aid groups" 5553:

Parker EP, Molodecky NA, Pons-Salort M, O'Reilly KM, Grassly NC (2015).

5186: 4911: 1828:

circulating undetected in regions inaccessible due to the activities of

1588:

both had 11. The following countries had single-digit numbers of cases:

13451: 13299: 12710: 12437:"Progress Toward Polio Eradication - Worldwide, January 2019-June 2021" 10036: 7181: 6710:"The CIA's fake vaccination drive has damaged the battle against polio" 6669:"Outbreak of vaccine-preventable diseases in Muslim majority countries" 5660: 5370:"Two New Vaccines Join the Fight to Eradicate Polio | UC San Francisco" 5101: 5083:

Global Polio Eradication Initiative, World Health Organization (2003).

4434: 3999: 3844: 3677: 3493: 3311: 2819: 2660: 2599: 2426: 2196: 2104: 1939: 1898: 1829: 1807: 1783: 1737: 1644: 1621: 1617: 1577: 1498: 1384: 1366: 1344: 1209: 549: 408: 367: 292: 231: 200: 196: 105: 61: 51: 12947: 11019:"Polio spreads in Afghanistan and Pakistan 'due to unchecked borders'" 10953:"To Calm Nervous Families, Pakistan Changes Polio Vaccination Tactics" 6074: 5552: 12166:(Press release). Global Polio Eradication Initiative. 16 March 2023. 8286:"What led to the Nigerian boycott of the polio vaccination campaign?" 8222:"Europe achieves historic milestone as Region is declared polio-free" 6477:"Health workers murdered as Pakistan vaccinates 8.4 million children" 4457: 4250: 3631: 3141: 1880: 1769: 1753: 1710: 1525: 1481:

community whose members predominantly were not vaccinated for polio.

1462: 1450: 1134: 288: 272: 177: 12106:(Press release). New York State Department of Health. 21 July 2022. 11922:"WHO Cautions Against Complacency as Pakistan Marks Polio-Free Year" 11088:"Pakistan, on verge of eradicating polio virus, faces human hurdles" 7961:"The End of Polio: Photographs of Sebastião Salgado Opens to Public" 4785: 1365:

In August 2003, rumors spread in some states in Nigeria, especially

157:

2 (WPV2) was in 1999, and WPV2 was declared eradicated in 2015. Type

27:

Effort to permanently eliminate all cases of poliomyelitis infection

13806: 12952: 12948: 12906: 12874: 12553: 9274: 6923: 4342: 4158: 4060: 3913: 3729: 3372: 3118: 2980: 2637: 2334: 2219: 2027: 1773: 1757: 1695: 1678: 1597: 1490: 1221: 1183: 1163: 1079: 416: 245:

The most important step in eradication of polio is interruption of

173: 132: 101: 8798:

Centers for Disease Control and Prevention (CDC) (23 March 2012).

8744:

Centers for Disease Control and Prevention (CDC) (12 April 2013).

6954:"Up in arms: EPI workers threaten to boycott polio drives in FATA" 5034:

Centers for Disease Control and Prevention (CDC) (December 1999).

1170:) was launched; National Immunization Days were coordinated in 19 12681: 12639: 12596: 10316: 8513:

Centers for Disease Control and Prevention (CDC) (October 2005).

7990:

Centers for Disease Control and Prevention (CDC) (October 1994).

4365: 4319: 4083: 3978: 3867: 3654: 3424: 3095: 3072: 2957: 2911: 2773: 2573: 2518: 2495: 2472: 2380: 2173: 2054: 1872: 1841: 1761: 1670: 1605: 1581: 1533: 1432: 1424: 1155: 617: 315:

Somali boy receiving injection of inactivated polio vaccine (IPV)

219: 146: 12131:"Polio found in New York wastewater as state urges vaccinations" 7992:"Certification of poliomyelitis eradication--the Americas, 1994" 7603:"Polio eradication: mobilizing and managing the human resources" 6924:"Protesting health workers threaten to boycott anti-polio drive" 4943:

Cockburn TA (April 1961). "Eradication of infectious diseases".

1427:-derived poliovirus). Most cases were located in two areas: the 1411: All cases in were due to circulating vaccine-derived virus 539:

states, set against the low (~80% after three doses against type

139:

infection in vaccinated individuals, particularly those who are

11989:"Gunmen in northwest Pakistan kill polio worker, two policemen" 11758:(Report). Pakistan Polio Eradication Programme. September 2022. 11391:"Impact of COVID-19 Pandemic on Global Poliovirus Surveillance" 11301:"Labs confirm 1st new case of polio in Philippines in 26 years" 10034: 6277:

Diop OM, Burns CC, Sutter RW, Wassilak SG, Kew OM (June 2015).

5347:

Global Polio Eradication Initiative - World Health Organization

4296: 4273: 3890: 3821: 3470: 3164: 2934: 2265: 2004: 1741: 1589: 1549: 1417: 1225: 1217: 1179: 1171: 1167: 1114: 553: 77: 60:, the goal of permanent global cessation of circulation of the 12222:"Polio in US, UK and Israel reveals rare risk of oral vaccine" 11239:

Circulating vaccine-derived poliovirus type 2 – African Region

10534:(Report). Pakistan Polio Eradication Programme. February 2019. 10453:(Report). Global Polio Eradication Initiative. November 2019. 9894: 7235:"Case 5: Eliminating Polio in Latin America and the Caribbean" 5485: 1423:

In 2005, there were 1,979 cases of wild poliovirus (excluding

12586: 12434: 11643:"Statement of the twenty-fifth polio IHR Emergency Committee" 10313:"WHO says child from Raqqa among 15 new polio cases in Syria" 7808:(13th ed.). Washington, D.C.: Public Health Foundation. 5086:

Global polio eradication initiative: strategic plan 2004–2008

4411: 4181: 4106: 3798: 3706: 3585: 3562: 3210: 3003: 2865: 2842: 2750: 2311: 2150: 2077: 1765: 1749: 1721: 1703: 1674: 1666: 1662: 1569: 1561: 1557: 1532:, which reported 41 cases, Chad with 22 cases, and Niger and 1478: 1454: 1446: 1440: 1374: 1213: 1191: 632: 622: 532: 528: 65: 12385:. Seventy-Fifth World Health Assembly. 6 May 2022. p. 5 12380:"Poliomyelitis eradication — Report by the Director-General" 9271:"Polio strain in Syria originated in Pakistan, WHO confirms" 7439:"WHO experts signal victory over one of three polio strains" 7127: 4552: 655:

immunization campaign, hoping to collect blood samples from

12606: 12191:"Burundi officials detect polio outbreak linked to vaccine" 11784:"Malawi finds Africa's first wild polio case in five years" 11388: 10544: 10231: 9827: 8045:. Government of India; Department of Family Welfare. 2013. 7802:

Epidemiology and Prevention of Vaccine-Preventable Diseases

6584: 4388: 4227: 3516: 3447: 3049: 3026: 2796: 1609: 1593: 1545: 1489:

In 2006, only four countries in the world (Nigeria, India,

1204:

Also in October 1999, The CORE Group—with funding from the

1138: 1071: 1066: 557: 183: 12273:"Poliovirus detected in sewage from North and East London" 12020:. Muscat, Oman: World Health Organization. 4 October 2022. 9139:"Poliovirus detected from environmental samples in Israel" 7128:

McCarthy KA, Chabot-Couture G, Shuaib F (September 2016).

6889: 6425: 6071:"Eradicating Polio: A Model for International Cooperation" 4758:"GPEI-Two out of three wild poliovirus strains eradicated" 403:

Polio vaccination is also important in the development of

260:

High infant immunization coverage with four doses of oral

12275:(Press release). UK Health Security Agency. 22 June 2022. 11833: 11450: 11273: 11124: 10726:"Circulating vaccine-derived poliovirus type 2 – Nigeria" 10346:"Circulating vaccine-derived poliovirus type 2 – Somalia" 9305: 9262: 8800:"Progress Toward Global Polio Eradication — Africa, 2011" 8595:"First Lady of Nigeria inaugurates vaccination campaigns" 7408:"This Man Has Been Shedding The Polio Virus For 28 Years" 6526: 5252: 1540:

countries, Chad reported the greatest number (37 cases).

1137:

poliovirus poliomyelitis in the Americas was reported in

608: 6426:

Wahid B, Kumari B, Saifullah KM, Idrees M (March 2023).

5928: 5603:"International travel and health: Poliomyelitis (Polio)" 5426: 1477:

infant girl aged seven months (the index patient) in an

47: 11690:"Global Circulating Vaccine-derived Poliovirus (cVDPV)" 10690:"Global Circulating Vaccine-derived Poliovirus (cVDPV)" 10478: 10144: 7502:"Global Eradication Of Wild Poliovirus Type 2 Declared" 6890:

Grossman S, Phillips J, Rosenzweig L (23 August 2016).

6666: 6372: 6370: 6368: 6276: 5715: 1243:

for poliomyelitis per 100,000 inhabitants in 2004

1190:

region. In 2000, the Western Pacific Region (including

188:

Eradication of polio has been defined in various ways:

12529: 10812: 10596: 9799:"Summary of poliovirus circulation in 2016 – Pakistan" 9663:

Global Polio Eradication Initiative Annual Report 2016

9131: 9041:"Somalia records its first wild polio case since 2007" 6869:"White House: CIA has ended use of vaccine programmes" 6336: 6334: 6332: 5986: 5716:

Shaw L, Spears W, Billings L, Maxim P (October 2010).

5145:

Public Health Notifiable Disease Management Guidelines

4752: 4750: 4584:, a 2009 documentary film about the eradication effort 1866:

Polio vaccination in the Democratic Republic of Congo.

548:

mobilisation of community groups, and issues with the

449:(before 2000 may include small numbers of cVDPV cases) 12032:"Afghanistan's Security Challenges under the Taliban" 8981:"Pakistan close to getting rid of a polio virus: WHO" 8418:"WHO Vaccine Preventable Diseases: Monitoring system" 7538:"Two out of three wild poliovirus strains eradicated" 7308: 4689:"Rinderpest virus has been wiped out, scientists say" 1078:, launched an initiative to eradicate polio from the 11535:"Stakeholders celebrate Nigeria's polio-free status" 10985:"Statement of the Twentieth IHR Emergency Committee" 10089:"End of Outbreak in Lao Peoples Democratic Republic" 9985: 6764: 6365: 5826:"Two New Vaccines Join the Fight to Eradicate Polio" 4718: 4716: 4714: 584: 11561:"Africa declared free of wild polio in 'milestone'" 10756:

Somalia cVDPV Outbreak Response Situation Report #3

10592: 10590: 9981: 9979: 6329: 5929:Duintjer Tebbens RJ, Thompson KM (September 2015). 5849: 4747: 13988:Public health emergencies of international concern 12046: 11803: 11801: 10684: 10682: 10680: 10678: 10676: 10674: 10672: 10670: 10668: 9763:"Semi-Annual Status Report: July to December 2016" 9302:"A $ 5.5 Billion Road Map To Banish Polio Forever" 6742:"Bin Laden death: 'CIA doctor' accused of treason" 6419: 4588:List of diseases eliminated from the United States 1206:United States Agency for International Development 411:), a susceptible human population, and a cycle of 12766:London Declaration on Neglected Tropical Diseases 12413:WHO Global Action Plan for Poliovirus Containment 12122: 11829: 11827: 11499: 11156:Center for Infectious Disease Research and Policy 9407:"WHO South-East Asia Region certified polio-free" 9194: 9161: 8849:American Journal of Tropical Medicine and Hygiene 6527:Ghinai I, Willott C, Dadari I, Larson HJ (2013). 5595: 4711: 206:As control of an infection to the point at which 149:is the latest country to have officially stopped 68:(polio) it causes, is the aim of a multinational 13964: 12158: 12156: 11899:"Pakistan Detects First Polio Case in 15 Months" 11684: 10649:(Press release). WHO:Africa. 13 September 2018. 10587: 10274: 9976: 9633:"WHO urges polio vaccine dose cut amid shortage" 8651: 7123: 7121: 6773:"American NGOs assail CIA over fake polio drive" 5147:. Alberta Government Health and Wellness. 2018. 1186:became the last person to contract polio in the 1095:The End of Polio: Global Effort to End a Disease 111:Prevention of disease spread is accomplished by 11798: 11682: 11680: 11678: 11676: 11674: 11672: 11670: 11668: 11666: 11664: 11446: 11444: 10665: 10340: 10338: 10283:"Polio outbreak is reported in Syria, WHO says" 9437:"Polio-free certification: WHO South-East Asia" 9401: 9399: 9167: 9107:"Egypt: Polio Virus Is Found in Cairo's Sewers" 8340:International Committee of the Red Cross (ICRC) 8188: 7496: 7494: 7492: 7177: 7175: 5306: 1439:campaign to increase polio immunization rates, 11824: 9206:"Polio Virus Discovered in Sewage From Israel" 8133: 7765: 7763: 7706: 7704: 7702: 7700: 7698: 7696: 7694: 7692: 7690: 7688: 7600: 7016: 7014: 6987:"Syria's Polio Epidemic: The Suppressed Truth" 6804:"'Emergency plan' to eradicate polio launched" 2565:engineered to allow vaccination against strain 1513:, wife of recently elected Nigerian president 210:of the disease ceased within a specified area. 13938: 12933: 12515: 12153: 12096: 11884:"GPEI statement on Mozambique WPV1 detection" 11708: 11637: 11635: 11085: 10863:Papua New Guinea Polio Outbreak Response 2018 10538: 9539:"GPEI-Circulating vaccine-derived poliovirus" 9503:Semi-Annual Status Report, July-December 2015 9368:Semi-Annual Status Report, July-December 2014 9032: 9004: 9002: 8700: 8698: 8696: 8694: 8692: 8690: 8261:(Press release). 7 April 2003. Archived from 7761: 7759: 7757: 7755: 7753: 7751: 7749: 7747: 7745: 7743: 7118: 7022:"WHO Removes Nigeria from Polio-Endemic List" 4781: 4779: 4722: 678: 575:In a 2012 interview with Pakistani newspaper 431: 424:, then the pathogen will eventually die off. 13978:Infectious diseases with eradication efforts 11762: 11661: 11441: 10368: 10335: 9467:Semi-Annual Status Report, January-June 2015 9396: 9332:Semi-Annual Status Report, January-June 2014 9293: 9170:"More polio virus traces detected in Israel" 8452: 8373: 8371: 8369: 8367: 8365: 8363: 8361: 7594: 7489: 7172: 6701: 5163: 4593:Mathematical modelling of infectious disease 3998: 3310: 2598: 1938: 1727:In April 2013, the WHO announced a new $ 5.5 1147:In 1994, the Indian Government launched the 92:, have spearheaded the campaign through the 12441:MMWR. Morbidity and Mortality Weekly Report 12306: 12304: 12302: 12182: 12044: 11840:MMWR. Morbidity and Mortality Weekly Report 11457:MMWR. Morbidity and Mortality Weekly Report 11395:MMWR. Morbidity and Mortality Weekly Report 10819:MMWR. Morbidity and Mortality Weekly Report 10603:MMWR. Morbidity and Mortality Weekly Report 10551:MMWR. Morbidity and Mortality Weekly Report 10485:MMWR. Morbidity and Mortality Weekly Report 10415:"Weekly AFP surveillance updates: Pakistan" 10238:MMWR. Morbidity and Mortality Weekly Report 10227: 10225: 10223: 10151:MMWR. Morbidity and Mortality Weekly Report 9992:MMWR. Morbidity and Mortality Weekly Report 9901:MMWR. Morbidity and Mortality Weekly Report 9837:MMWR. Morbidity and Mortality Weekly Report 8522:MMWR. Morbidity and Mortality Weekly Report 7999:MMWR. Morbidity and Mortality Weekly Report 7928: 7926: 7924: 7922: 7794: 7792: 7685: 7657: 7655: 7653: 7651: 7649: 7647: 7645: 7643: 7641: 7565: 7563: 7532: 7530: 7087: 7085: 7083: 7052: 7050: 7011: 6795: 6734: 6379:"Religious opposition to polio vaccination" 6286:MMWR. Morbidity and Mortality Weekly Report 5996:MMWR. Morbidity and Mortality Weekly Report 5767:"Population Immunity and Polio Eradication" 5436:MMWR. Morbidity and Mortality Weekly Report 5392: 5390: 5223: 5221: 5219: 5217: 5215: 5213: 5211: 4792:MMWR. Morbidity and Mortality Weekly Report 4650: 1681:, the first non-imported cases since 1994. 1399: Polio had re-established transmission 1197:In October 1999, the last isolation of type 704:International wild poliovirus cases by year 84:. These organizations, along with the U.S. 12940: 12926: 12522: 12508: 11632: 11149: 10192: 10190: 8999: 8814:Centers for Disease Control and Prevention 8760:Centers for Disease Control and Prevention 8687: 8555: 8506: 8448: 8446: 8277: 8129: 8127: 7965:Centers for Disease Control and Prevention 7740: 7226: 6828: 6089: 5830:The University of California San Francisco 5661:"Herd immunity: history, theory, practice" 5374:The University of California San Francisco 5233:Global Polio Eradication Initiative (GPEI) 4776: 1820:of a lower dose than used in the standard 1665:reported its first case since 2009, while 1119:Centers for Disease Control and Prevention 447:Number of wild poliovirus cases, 1975–2022 86:Centers for Disease Control and Prevention 13121:"Cocoliztli" epidemics in colonial Mexico 12462: 12452: 11859: 11476: 11416: 11406: 11118: 10947: 10838: 10622: 10570: 10504: 10442: 10440: 10280: 10257: 10170: 10064: 10011: 9920: 9856: 9600: 9200: 9101: 8869: 8767: 8455:"Polio Spreads From Nigeria After Claims" 8358: 8311: 8301: 8170:"CORE Group Polio Eradication Initiative" 7983: 7621: 7610:Bulletin of the World Health Organization 7344: 7334: 7209: 7199: 7155: 7145: 6684: 6610: 6552: 6500: 6451: 6402: 6297: 6253: 6229: 6212: 6202: 6184: 6015: 5956: 5946: 5875: 5800: 5782: 5741: 5631: 5578: 5514: 5447: 5302: 5300: 5280: 5270: 4919: 4900:Bulletin of the World Health Organization 4889: 4887: 4811: 4525: 1473:1 infection occurred in an unvaccinated, 480:2 virus, while a separate monovalent type 222:; that diagnostic tools, with sufficient 12406: 12404: 12402: 12400: 12299: 11772:(Press release). GPEI. 17 February 2022. 11728: 10943: 10941: 10781:"Polio outbreak confirmed in Mozambique" 10220: 10117: 10035:Duizer E, Ruijs WL, van der Weijden CP, 9299: 9038: 8978: 8626: 8479: 8410: 7932: 7919: 7854:Epidemiologie, Mikrobiologie, Imunologie 7789: 7638: 7560: 7527: 7080: 7047: 6580: 6578: 6576: 6574: 6572: 6522: 6520: 6474: 6376: 6064: 6062: 6060: 6058: 6056: 6054: 6052: 6050: 5387: 5208: 4942: 1897: 1861: 1806: 1782: 1651: 1643: 1383: 1235: 1044: 873: 855: 837: 819: 803: 785: 769: 751: 733: 657:Osama bin Laden's compound in Abbottabad 394: 310: 184:Factors influencing eradication of polio 46: 38: 12781:Malaria Eradication Scientific Alliance 12284: 12282: 11807: 11718:(Press release). GPEI. 11 October 2021. 11355: 10897: 10187: 9943: 9805:(WHO). 27 December 2016. Archived from 9569:"Global synchronisation and the switch" 9268: 8443: 8124: 8108:(WHO). 30 November 2001. Archived from 7367: 6984: 5982: 5980: 5978: 5976: 4893: 1709:In April 2013, a case of wild polio in 366:The inactivated polio vaccine (IPV, or 354:the eradication of wild poliovirus type 237:and cannot amplify in the environment. 14: 13965: 12419:. Global Polio Eradication Initiative. 12368:. Global Polio Eradication Initiative. 12317:. Global Polio Eradication Initiative. 12128: 11532: 11333:(Press release). GPEI. 18 March 2020. 11311:from the original on 20 September 2019 11280:from the original on 19 September 2019 11180: 11016: 10437: 9697: 9168:Sterman A, Winer Jr S (12 June 2013). 9071:"Somalia hit by severe polio outbreak" 8283: 8198:. Rotary International. Archived from 8020:from the original on 13 September 2017 7890: 7884: 7843: 7515:from the original on 12 September 2016 6849:from the original on 11 September 2013 6801: 6707: 6673:Journal of Infection and Public Health 6235: 6073:. Worldwatch Institute. Archived from 6068: 5297: 4884: 663:. In a letter written to CIA director 399:Herd Immunity vs Without Herd Immunity 119:—oral polio vaccine (OPV), which uses 13188:Great Plague in the late Ming dynasty 12921: 12503: 12397: 12329:"Polio containment and certification" 12219: 12188: 11942: 11753:Pakistan Polio Update, September 2021 11607: 11571: 11541:from the original on 3 September 2020 11298: 11189:from the original on 23 December 2019 11086:Constable P, Khan HN (5 March 2019). 11031:from the original on 20 February 2019 10938: 10761:(Report). WHO, UNICEF. 20 August 2018 10653:from the original on 23 November 2019 10460:from the original on 23 November 2019 10122:. Outbreak News Today. Archived from 10057:10.2807/1560-7917.ES.2017.22.21.30542 9613:from the original on 8 September 2018 9545:from the original on 28 February 2020 9519:from the original on 10 November 2016 9250:from the original on 11 December 2019 8805:Morbidity and Mortality Weekly Report 8751:Morbidity and Mortality Weekly Report 8639:from the original on 31 December 2016 7941:from the original on 11 December 2006 7728:from the original on 31 December 2022 7436: 7106:from the original on 6 September 2018 6999:from the original on 1 September 2018 6770: 6633: 6569: 6517: 6432:Asia-Pacific Journal of Public Health 6340: 6238:"The bumpy road to polio eradication" 6047: 5823: 5680:10.1093/oxfordjournals.epirev.a036121 5467:from the original on 23 November 2017 5367: 4686: 601:United States invasion of Afghanistan 100:has been achieved twice before, with 12807:National Malaria Eradication Program 12353: 12279: 12253:. The Associated Press. 23 June 2022 11645:(Press release). WHO. 23 June 2020. 11267: 11219:from the original on 2 November 2019 10794:from the original on 23 October 2019 10732:(WHO). 8 August 2018. Archived from 10706:from the original on 16 October 2022 10529:Pakistan Polio Update, February 2019 10425:from the original on 14 January 2019 9964:from the original on 17 January 2018 9710:from the original on 28 October 2019 9643:from the original on 28 October 2019 9443:(WHO). 27 March 2014. Archived from 9413:(WHO). 27 March 2014. Archived from 9083:from the original on 5 December 2019 8461:from the original on 5 November 2018 7937:. Pan American Health Organization. 7771:"Global Wild Poliovirus 2017 - 2024" 7712:"Global Wild Poliovirus 2016 - 2022" 7601:Aylward RB, Linkins J (April 2005). 7477:from the original on 11 October 2017 7445:from the original on 11 October 2017 7068:from the original on 31 October 2018 6834: 6783:from the original on 1 November 2013 5973: 5764: 5658: 5652: 5420: 5151:from the original on 28 October 2019 1669:reported 21 cases, mostly among the 1405: Cases were importation-related 1245: 12771:Global Polio Eradication Initiative 12493:Global Polio Eradication Initiative 12018:Global Polio Eradication Initiative 11919: 11896: 11886:(Press release). GPEI. 18 May 2022. 11620:from the original on 25 August 2020 11589:from the original on 25 August 2020 11245:(WHO). 31 July 2019. Archived from 11209:"Mapped: Where polio lives in 2019" 11058:Global Polio Eradication Initiative 10879:from the original on 27 August 2020 10786:Global Polio Eradication Initiative 10352:(WHO). 9 March 2018. Archived from 10204:(WHO). 10 July 2018. Archived from 10093:Global Polio Eradication Initiative 9770:Global Polio Eradication Initiative 9670:Global Polio Eradication Initiative 9574:Global Polio Eradication Initiative 9510:Global Polio Eradication Initiative 9474:Global Polio Eradication Initiative 9375:Global Polio Eradication Initiative 9339:Global Polio Eradication Initiative 9312:from the original on 3 October 2015 9238:"Polio outbreak in Syria confirmed" 9051:from the original on 1 October 2015 9018:Global Polio Eradication Initiative 8938:The New England Journal of Medicine 8909:Global Polio Eradication Initiative 8714:Global Polio Eradication Initiative 8666:Global Polio Eradication Initiative 8600:Global Polio Eradication Initiative 8563:"Bangladesh begins new polio drive" 8494:from the original on 29 August 2013 8387:Global Polio Eradication Initiative 8346:from the original on 12 August 2006 8228:(WHO). 21 June 2002. Archived from 7872:from the original on 27 August 2020 7569: 7542:Global Polio Eradication Initiative 7507:Global Polio Eradication Initiative 7457: 7282:Global Polio Eradication Initiative 6966:from the original on 25 August 2016 6934:from the original on 27 August 2016 6904:from the original on 24 August 2016 6242:The New England Journal of Medicine 6191:The New England Journal of Medicine 6158:Global Polio Eradication Initiative 6035:from the original on 26 August 2020 5904:Global Polio Eradication Initiative 5534:from the original on 27 August 2020 5402:Global Polio Eradication Initiative 5335: 5121:from the original on 20 August 2017 4735:from the original on 26 August 2020 4575:Global Polio Eradication Initiative 1883:resulted from a distinct outbreak. 1536:, each of which reported 11 cases. 1503:Map of reported polio cases in 2006 1388:Countries with polio cases in 2005 1178:countries. In 1998, Melik Minas of 1123:Global Polio Eradication Initiative 642:Federally Administered Tribal Areas 279:without other obvious cause (e.g., 94:Global Polio Eradication Initiative 24: 12531:Eradication of infectious diseases 12427: 12201:from the original on 17 March 2023 12170:from the original on 17 March 2023 12141:from the original on 1 August 2022 12045:Abbott B, McKay B (2 April 2022). 11337:from the original on 21 March 2020 11131:from the original on 26 April 2019 11067:from the original on 29 March 2019 10998:from the original on 12 March 2019 9779:from the original on 28 April 2017 9281:from the original on 31 March 2019 9145:(WHO). 3 June 2013. Archived from 8718:. 9 September 2015. Archived from 8629:"Pakistan polio case in Australia" 8575:from the original on 25 April 2019 8078:(WHO). 2 June 2006. Archived from 7418:from the original on 26 March 2018 7388:from the original on 29 March 2018 7290:from the original on 26 March 2018 7232: 6648:from the original on 29 March 2014 5495:The Journal of Infectious Diseases 5321:10.1093/oxfordjournals.aje.a112848 4723:Scherbel-Ball N (25 August 2020). 4680: 1902:Countries with polio cases in 2020 1811:Countries with polio cases in 2016 1787:Countries with polio cases in 2015 1702:, and the Middle East (focused in 1648:Countries with polio cases in 2011 98:eradication of infectious diseases 25: 14004: 12870:Mathematical modelling of disease 12481: 12362:Polio Post-Certification Strategy 12110:from the original on 21 July 2022 11649:from the original on 15 July 2020 11500:Rauhala E, Paquette D, George S. 11370:from the original on 6 April 2020 11119:Saifi S, Shah S (26 April 2019). 11100:from the original on 6 March 2019 10926:from the original on 12 July 2019 10395:from the original on 5 March 2020 10323:from the original on 20 June 2017 10099:from the original on 1 March 2019 9876:from the original on 19 June 2019 9679:from the original on 24 June 2018 9483:from the original on 12 June 2018 9384:from the original on 29 June 2017 9348:from the original on 29 June 2017 9182:from the original on 11 July 2017 8482:"Indonesia faces polio challenge" 8052:from the original on 14 July 2014 7971:from the original on 29 June 2017 7825:from the original on 30 June 2019 7673:from the original on 2 April 2015 6752:from the original on 11 July 2020 6722:from the original on 11 July 2020 6317:from the original on 29 June 2020 5910:from the original on 26 June 2018 5408:from the original on 28 June 2018 5196:from the original on 20 June 2017 4994:MMWR. Recommendations and Reports 4872:from the original on 28 July 2020 4842:from the original on 22 July 2020 4512:, and Yemen and Palestine in the 585:Opposition to vaccination efforts 72:effort begun in 1988, led by the 13893:encephalitis lethargica epidemic 12737:Bovine spongiform encephalopathy 12372: 12339: 12321: 12265: 12239: 12213: 12066: 12038: 12024: 12003: 11981: 11959: 11936: 11913: 11890: 11876: 11776: 11745: 11722: 11601: 11583:WHO | Regional Office for Africa 11553: 11526: 11514:from the original on 1 July 2020 11493: 11382: 11349: 11323: 11292: 11261: 11231: 11201: 11174: 11162:from the original on 17 May 2019 11143: 11112: 11079: 11043: 11010: 10977: 10965:from the original on 29 May 2019 10891: 10855: 10806: 10773: 10748: 10718: 10639: 10521: 10472: 10407: 10305: 10293:from the original on 8 June 2017 10138: 10111: 10081: 10028: 9937: 9888: 9821: 9791: 9755: 9722: 9691: 9655: 9625: 9594: 9561: 9531: 9495: 9459: 9429: 9360: 9324: 9230: 9218:from the original on 4 June 2013 9119:from the original on 4 June 2013 9095: 9063: 8987:from the original on 23 May 2013 8972: 8924: 8896: 8835: 8791: 8737: 8620: 8587: 8543:from the original on 9 July 2020 8391:. 3 January 2012. Archived from 8379:"Wild Poliovirus List 2005-2011" 7935:"The Man Who Made Polio History" 7905:10.1001/jama.1984.03340460072029 7254:from the original on 9 June 2017 6816:from the original on 26 May 2012 6353:from the original on 29 May 2012 5718:"Effective Vaccination Policies" 5697:from the original on 9 July 2020 5640:from the original on 8 July 2018 5309:American Journal of Epidemiology 5015:from the original on 29 May 2020 4563: 4551: 1602:Democratic Republic of the Congo 1530:Democratic Republic of the Congo 463:Number of cVDPV cases, 2000-2023 456: 440: 390: 374:in the arm or leg, but recently 319:There are two distinct types of 13671:Gorakhpur Japanese encephalitis 12968:List of epidemics and pandemics 12802:Boll Weevil Eradication Program 12776:Global Certification Commission 9700:"How polio returned to Nigeria" 8480:Aglionby J (2 September 2005). 8473: 8328: 8244: 8214: 8162: 8094: 8064: 8032: 7953: 7837: 7430: 7400: 7361: 7302: 7269: 7031:(Press release). Archived from 6978: 6946: 6916: 6883: 6861: 6660: 6627: 6591:The Pan African Medical Journal 6468: 6270: 6178: 6145: 6115: 5922: 5892: 5843: 5817: 5758: 5709: 5625: 5546: 5479: 5361: 5246: 5141:"Acute Flaccid Paralysis (AFP)" 5133: 5076: 5064:from the original on 8 May 2019 5027: 4979: 4936: 4725:"Africa declared free of polio" 4699:from the original on 3 May 2019 4658:"Smallpox [Fact Sheet]" 1360:2002 Global polio incidence map 1166:, Central Asian Republics, and 496: 13634: 11808:Roberts L (17 February 2022). 11729:Sullivan B (19 October 2021). 9269:Nebehay S (11 November 2013). 8979:Choudary A (27 January 2013). 8604:. 30 July 2007. Archived from 6985:Sparrow A (20 February 2014). 6603:10.11604/pamj.2016.24.120.8986 6097:"Polio Eradication Evaluation" 5000:(RR-16): 1–38. December 1993. 4854: 4828: 4620: 4608:2024 Gaza Strip polio outbreak 1848:, a center of fighting in the 378:using a lower dose (so-called 323:. Oral polio vaccine (OPV, or 306: 78:United Nations Children's Fund 13: 1: 12996: 12581:Eradication of dracunculiasis 12078:Weekly Epidemiological Record 11299:Clyde H (19 September 2019). 11181:Farmer B (20 November 2019). 11017:Nishat A (20 February 2019). 9944:Roberts L (11 January 2018). 8904:"China – one year polio-free" 8453:Balint-Kurti D (4 May 2005). 7368:Roberts L (11 January 2018). 7243:Center for Global Development 6341:Teepu IA (26 February 2012). 5632:Branswell H (20 March 2014). 5571:10.1586/14760584.2015.1052800 5343:"GPEI-OPV Oral polio vaccine" 4965:10.1126/science.133.3458.1050 4613: 3996:Confirmed polio cases in 2024 3308:Confirmed polio cases in 2023 2596:Confirmed polio cases in 2022 1936:Confirmed polio cases in 2021 1241:Disability-adjusted life year 1129:'s 1985 pledge to raise $ 120 1040: 64:and hence elimination of the 12495:. World Health Organization. 12084:(22): 239–256. 2 June 2023. 11331:"GPEI statement on COVID-19" 11268:Hunt K (19 September 2019). 11150:Schnirring L (17 May 2019). 9698:Okafor JL (11 August 2016). 9300:Beaubien J (26 April 2013). 8303:10.1371/journal.pmed.0040073 7572:"Ending polio—now or never?" 7336:10.1371/journal.pone.0180608 6992:The New York Review of Books 6634:Walsh D (14 February 2007). 6545:10.1080/17441692.2013.859720 6383:Emerging Infectious Diseases 6185:Pallansch MA (August 2018). 6069:Mastny L (25 January 1999). 5900:"Vaccine-Derived Poliovirus" 4894:Barrett S (September 2004). 1802: 1656:Polio vaccination in Tehran. 1639: 1484: 1231: 1194:) was certified polio-free. 1100: 513: 7: 11945:"Polio's back. Blame Covid" 10281:Branswell H (8 June 2017). 9601:Branswell H (19 May 2017). 8706:"Wild Poliovirus 2010–2015" 8627:Yusufzai A (30 July 2007). 8424:(WHO). 2014. Archived from 7437:Miles T (23 October 2015). 6343:"WHO rejects polio rumours" 4687:Ghosh P (14 October 2010). 4544: 1074:), under the leadership of 695: 651:(CIA) had conducted a fake 649:Central Intelligence Agency 240: 10: 14009: 13781:2024 Latin American dengue 13561:Western African meningitis 13375:Pacific Northwest smallpox 12220:Cheng M (21 August 2022). 12129:Heavey S (1 August 2022). 11991:. Al Jazeera. 28 June 2022 11608:Godoy M (25 August 2020). 11356:Roberts L (1 April 2020). 11305:United Press International 10898:Roberts L (10 July 2019). 10118:Herriman R (25 May 2017). 9039:Callaway E (13 May 2013). 8659:"WHO Wild Poliovirus List" 6686:10.1016/j.jiph.2017.09.007 5868:10.1016/j.chom.2020.04.003 5229:"OPV - Oral Polio Vaccine" 4836:"Endemic Countries - GPEI" 1091:UNICEF Goodwill Ambassador 679:Polio eradication criteria 588: 432:Vaccine-derived poliovirus 29: 13805: 13481: 13402: 13387:Buenos Aires yellow fever 13307: 13298: 13285:Philadelphia yellow fever 13255:Great Plague of Marseille 13249:Great Northern War plague 13243:Iceland smallpox epidemic 13235: 13156: 13101: 13090: 13027: 12983: 12976: 12963: 12865:Globalization and disease 12857: 12789: 12758: 12749: 12724: 12715:Eradication of rinderpest 12703: 12694: 12620: 12567: 12546: 12537: 12312:"GPEI Strategy 2022-2026" 12189:Cheng M (17 March 2023). 11943:Kenen J (28 March 2022). 11920:Gul A (28 January 2022). 11533:Essien G (20 June 2020). 11243:World Health Organization 10990:World Health Organization 10870:World Health Organization 10730:World Health Organization 10384:World Health Organization 10350:World Health Organization 10202:World Health Organization 9803:World Health Organization 9735:World Health Organization 9441:World Health Organization 9411:World Health Organization 9143:World Health Organization 8422:World Health Organization 8257:World Health Organization 8226:World Health Organization 8106:World Health Organization 8076:World Health Organization 7667:World Health Organization 7277:"Surveillance Indicators" 7201:10.1186/s12879-015-0791-5 7147:10.1186/s12879-016-1817-3 7098:World Health Organization 7062:World Health Organization 7027:World Health Organization 6771:Teepu IA (2 March 2012). 6444:10.1177/10105395231158866 6377:Warraich HJ (June 2009). 6127:World Health Organization 5948:10.1186/s12879-015-1114-6 5784:10.3390/pathogens13030183 5734:10.1016/j.ins.2010.06.005 5607:World Health Organization 5559:Expert Review of Vaccines 5179:World Health Organization 5094:World Health Organization 4662:World Health Organization 3993: 3305: 2593: 1933: 1107:World Health Organization 702: 115:. There are two kinds of 74:World Health Organization 18:Poliomyelitis eradication 13951:Mpox (clade Ib) epidemic 13945:Mpox (clade II) outbreak 13905:Seventh cholera pandemic 12897:Tuberculosis elimination 12817:India National PolioPlus 11969:. CBC News. 21 June 2022 11408:10.15585/mmwr.mm695152a4 8336:"Sudan: Bulletin No. 28" 8284:Jegede AS (March 2007). 7844:Slonim D (August 2005). 7578:. Unicef. Archived from 6802:Guerin O (24 May 2012). 6708:Larson H (27 May 2012). 6475:Yusufzai A (June 2014). 5824:Gadye L (14 June 2023). 5368:Gadye L (14 June 2023). 5272:10.3390/vaccines10081329 4632:Global Health Strategies 4508:except for Indonesia in 2889:Central African Republic 1574:Central African Republic 345:eradication initiative. 340:and indirectly inducing 168:As of August 2024, 13863:Fourth cholera pandemic 13845:Second cholera pandemic 13691:Équateur province Ebola 13279:North American smallpox 13194:Great Plague of Seville 12558:Eradication of smallpox 11897:Gul A (23 April 2022). 11786:. BBC. 18 February 2022 11733:. National Public Radio 10912:10.1126/science.aay6925 9958:10.1126/science.aas9789 8040:"Pulse Polio Programme" 7967:(CDC). 24 August 2007. 7669:(WHO). 6 January 2015. 7576:The Progress of Nations 7382:10.1126/science.aas9789 7188:BMC Infectious Diseases 7134:BMC Infectious Diseases 6835:Shah A (2 March 2012). 6236:Modlin JF (June 2010). 5935:BMC Infectious Diseases 5856:Cell Host & Microbe 4862:"Poliomyelitis (polio)" 3984: 3296: 2584: 1924: 1846:Deir ez-Zor Governorate 1393: Polio was endemic 372:intramuscular injection 13881:Sixth cholera pandemic 13869:Fifth cholera pandemic 13851:Third cholera pandemic 13839:First cholera pandemic 13821:Second plague pandemic 13381:Barcelona yellow fever 13226:Great Plague of Vienna 13212:Great Plague of London 13182:Massachusetts smallpox 12601:Eradication of malaria 12454:10.15585/mmwr.mm7034a1 11852:10.15585/mmwr.mm7049a1 11469:10.15585/mmwr.mm7115a2 11060:(GPEI). October 2018. 10831:10.15585/mmwr.mm6724a5 10615:10.15585/mmwr.mm6829a3 10563:10.15585/mmwr.mm6833a4 10497:10.15585/mmwr.mm6744a5 10250:10.15585/mmwr.mm6809a2 10163:10.15585/mmwr.mm6710a4 10004:10.15585/mmwr.mm6708a5 9913:10.15585/mmwr.mm6646a4 9849:10.15585/mmwr.mm6632a5 8668:(GPEI). Archived from 7663:"AFP/Polio Case Count" 7544:(GPEI). Archived from 6395:10.3201/eid1506.090087 6153:"Polio and Prevention" 6008:10.15585/mmwr.mm6813a4 5765:Fine PE (March 2024). 5501:(suppl_1): S161–S167. 5449:10.15585/mmwr.mm6533a5 4804:10.15585/mmwr.mm7319a4 4526:Post-Eradication Plans 4003: 3315: 2603: 1943: 1903: 1867: 1818:subcutaneous injection 1812: 1788: 1657: 1649: 1413: 1335: 1216:in South Asia, and in 1054: 599:In the context of the 400: 376:subcutaneous injection 316: 54: 44: 13857:Third plague pandemic 13815:First plague pandemic 13609:Western African Ebola 13519:Chikungunya outbreaks 13471:Malaysian Nipah virus 13339:Great Plains smallpox 12697:agricultural diseases 11579:"Polio certification" 10095:(GPEI). 29 May 2017. 8951:10.1056/NEJMoa1303368 8862:10.4269/ajtmh.19-0040 7064:(WHO). 6 March 2017. 6493:10.1503/cmaj.109-4776 6129:(WHO). Archived from 5668:Epidemiologic Reviews 5609:(WHO). Archived from 5507:10.1093/infdis/jix038 4664:(WHO). Archived from 4002: 3314: 2602: 1942: 1901: 1865: 1810: 1786: 1655: 1647: 1387: 1239: 1109:(WHO), together with 1048: 605:2003 invasion of Iraq 398: 314: 50: 42: 30:For the vaccine, see 13917:Russian flu pandemic 13659:Angolan yellow fever 13410:San Francisco plague 13363:Broad Street cholera 13261:Great Plague of 1738 12635:Lymphatic filariasis 12347:"GPEI-Certification" 12290:"Closing in on zero" 11537:. Voice of Nigeria. 11213:The New Humanitarian 9637:Agence France-Presse 9635:. Business Insider. 9010:"Annual Report 2013" 8856:(Suppl 4): 100–106. 8725:on 28 September 2015 8457:. Associated Press. 8196:"PolioPlus Timeline" 8156:10.1093/her/16.1.109 8112:on 22 September 2005 7933:Fujimura SF (2005). 7721:. 27 December 2022. 7035:on 27 September 2015 6930:. 5 September 2015. 6533:Global Public Health 6255:10.1056/nejmp1005405 6204:10.1056/NEJMp1808903 5722:Information Sciences 1127:Rotary International 1111:Rotary International 90:The Gates Foundation 13823:(1348–19th century) 13751:New Zealand measles 13579:Darfur yellow fever 13422:LA pneumonic plague 13039:Plague of Justinian 12611:Eradication of yaws 12053:Wall Street Journal 11507:The Washington Post 11401:(5152): 1648–1652. 11215:. 24 October 2019. 11093:The Washington Post 10699:. 11 October 2022. 9772:(GPEI). p. 8. 9246:. 29 October 2013. 9149:on 13 February 2014 9105:(23 January 2013). 8202:on 20 February 2011 8176:on 27 February 2009 8148:2001PDiff..16..110Y 8072:"Operation MECACAR" 7327:2017PLoSO..1280608C 6959:The Express Tribune 6897:The Washington Post 6166:on 7 September 2015 5189:. WHO/POLIO/15.02. 4957:1961Sci...133.1050C 4951:(3458): 1050–1058. 4628:"Polio Eradication" 4570:Medicine portal 1429:Indian subcontinent 1154:In 1995, Operation 603:and the subsequent 121:weakened poliovirus 96:(GPEI). Successful 13833:Influenza pandemic 13827:Influenza pandemic 13775:Bangsamoro measles 13757:Singaporean dengue 13721:Pacific NW measles 13715:Philippine measles 13703:Madagascar measles 13685:Kerala Nipah virus 13678:Saudi Arabian MERS 13591:Singaporean dengue 13537:Zimbabwean cholera 13507:Singaporean dengue 13351:Copenhagen cholera 13333:Groningen epidemic 13127:Influenza pandemic 13109:Influenza pandemic 11924:. Voice of America 11901:. Voice of America 11585:. 25 August 2020. 11249:on 20 October 2019 10958:The New York Times 10790:. 8 January 2019. 10356:on 20 October 2018 9743:on 19 January 2017 9211:The New York Times 9112:The New York Times 9079:. 16 August 2013. 8608:on 9 December 2007 7548:on 24 October 2019 6871:. BBC. 19 May 2014 6748:. 6 October 2011. 6133:on 24 October 2016 4764:on 7 November 2019 4668:on 3 February 2011 4558:Viruses portal 4506:Sub-Saharan Africa 4004: 3969:Khyber Pakhtunkhwa 3961:Sub-Saharan Africa 3316: 3283:Khyber Pakhtunkhwa 2604: 1944: 1904: 1868: 1813: 1789: 1658: 1650: 1414: 1336: 1055: 638:Khyber Pakhtunkhwa 401: 327:vaccine) contains 317: 55: 45: 13960: 13959: 13801: 13800: 13797: 13796: 13733:Kuala Koh measles 13647:South Korean MERS 13635:Polio declaration 13623:Madagascar plague 13555:Gujarat hepatitis 13543:Madagascar plague 13495:Midwest monkeypox 13446:Yugoslav smallpox 13416:Manchurian plague 13357:Stockholm cholera 13294: 13293: 13081:Sweating sickness 13069:Japanese smallpox 13018:Plague of Cyprian 12957:disease outbreaks 12915: 12914: 12853: 12852: 12829:Polio in Pakistan 12745: 12744: 12690: 12689: 12591:Polio eradication 12447:(34): 1129–1135. 12034:. 12 August 2022. 11846:(49): 1691–1699. 11567:. 25 August 2020. 11185:. The Telegraph. 10736:on 12 August 2018 10491:(44): 1242–1245. 10208:on 28 August 2018 10045:Euro Surveillance 9907:(46): 1276–1280. 9809:on 2 January 2017 9639:. 28 April 2017. 9409:(Press release). 8945:(21): 1981–1990. 8528:(41): 1053–1055. 8224:(Press release). 8104:(Press release). 7963:(Press release). 7899:(22): 2994–2996. 7815:978-0-9904491-1-9 7582:on 5 January 2018 7060:(Press release). 6962:. 26 April 2016. 6539:(10): 1138–1150. 6248:(25): 2346–2349. 5862:(5): 736–751.e8. 5728:(19): 3728–3744. 5111:978-92-4-159117-1 4603:Population health 4598:Polio in Pakistan 4496: 4495: 3974:Kandahar province 3952: 3951: 3272: 3271: 2557: 2556: 1911:COVID-19 pandemic 1475:immunocompromised 1333: 1332: 1188:Indo-West Pacific 1121:(CDC) passed the 1087:Sebastião Salgado 1038: 1037: 640:(KPK) and in the 570:chronic excretors 82:Rotary Foundation 80:(UNICEF) and the 58:Polio eradication 16:(Redirected from 14000: 13973:Health campaigns 13940: 13727:New York measles 13681: 13641:Indian swine flu 13629:Odisha hepatitis 13619: 13573:Pakistani dengue 13525:Pakistani dengue 13474: 13440:Wrocław smallpox 13393:Hong Kong plague 13327:Caragea's plague 13305: 13304: 13222: 13115:Mexican smallpox 13099: 13098: 13051:Plague of Sheroe 13006:Plague of Athens 13001: 12998: 12981: 12980: 12942: 12935: 12928: 12919: 12918: 12835:Every Last Child 12756: 12755: 12732:Ovine rinderpest 12701: 12700: 12544: 12543: 12524: 12517: 12510: 12501: 12500: 12496: 12476: 12466: 12456: 12421: 12420: 12418: 12408: 12395: 12394: 12392: 12390: 12384: 12376: 12370: 12369: 12367: 12357: 12351: 12350: 12343: 12337: 12336: 12325: 12319: 12318: 12316: 12308: 12297: 12296: 12294: 12286: 12277: 12276: 12269: 12263: 12262: 12260: 12258: 12243: 12237: 12236: 12234: 12232: 12217: 12211: 12210: 12208: 12206: 12186: 12180: 12179: 12177: 12175: 12160: 12151: 12150: 12148: 12146: 12126: 12120: 12119: 12117: 12115: 12100: 12094: 12093: 12070: 12064: 12063: 12061: 12059: 12050: 12042: 12036: 12035: 12028: 12022: 12021: 12015: 12007: 12001: 12000: 11998: 11996: 11985: 11979: 11978: 11976: 11974: 11963: 11957: 11956: 11954: 11952: 11940: 11934: 11933: 11931: 11929: 11917: 11911: 11910: 11908: 11906: 11894: 11888: 11887: 11880: 11874: 11873: 11863: 11831: 11822: 11821: 11819: 11817: 11805: 11796: 11795: 11793: 11791: 11780: 11774: 11773: 11766: 11760: 11759: 11757: 11749: 11743: 11742: 11740: 11738: 11726: 11720: 11719: 11712: 11706: 11705: 11703: 11701: 11686: 11659: 11658: 11656: 11654: 11639: 11630: 11629: 11627: 11625: 11605: 11599: 11598: 11596: 11594: 11575: 11569: 11568: 11557: 11551: 11550: 11548: 11546: 11530: 11524: 11523: 11521: 11519: 11497: 11491: 11490: 11480: 11448: 11439: 11438: 11420: 11410: 11386: 11380: 11379: 11377: 11375: 11353: 11347: 11346: 11344: 11342: 11327: 11321: 11320: 11318: 11316: 11296: 11290: 11289: 11287: 11285: 11265: 11259: 11258: 11256: 11254: 11235: 11229: 11228: 11226: 11224: 11205: 11199: 11198: 11196: 11194: 11178: 11172: 11171: 11169: 11167: 11147: 11141: 11140: 11138: 11136: 11116: 11110: 11109: 11107: 11105: 11083: 11077: 11076: 11074: 11072: 11066: 11055: 11047: 11041: 11040: 11038: 11036: 11014: 11008: 11007: 11005: 11003: 10981: 10975: 10974: 10972: 10970: 10945: 10936: 10935: 10933: 10931: 10895: 10889: 10888: 10886: 10884: 10878: 10867: 10859: 10853: 10852: 10842: 10810: 10804: 10803: 10801: 10799: 10777: 10771: 10770: 10768: 10766: 10760: 10752: 10746: 10745: 10743: 10741: 10722: 10716: 10715: 10713: 10711: 10705: 10694: 10686: 10663: 10662: 10660: 10658: 10643: 10637: 10636: 10626: 10594: 10585: 10584: 10574: 10542: 10536: 10535: 10533: 10525: 10519: 10518: 10508: 10476: 10470: 10469: 10467: 10465: 10459: 10452: 10444: 10435: 10434: 10432: 10430: 10411: 10405: 10404: 10402: 10400: 10394: 10380: 10372: 10366: 10365: 10363: 10361: 10342: 10333: 10332: 10330: 10328: 10319:. 20 June 2017. 10309: 10303: 10302: 10300: 10298: 10278: 10272: 10271: 10261: 10229: 10218: 10217: 10215: 10213: 10194: 10185: 10184: 10174: 10142: 10136: 10135: 10133: 10131: 10115: 10109: 10108: 10106: 10104: 10085: 10079: 10078: 10068: 10032: 10026: 10025: 10015: 9983: 9974: 9973: 9971: 9969: 9941: 9935: 9934: 9924: 9892: 9886: 9885: 9883: 9881: 9875: 9860: 9834: 9825: 9819: 9818: 9816: 9814: 9795: 9789: 9788: 9786: 9784: 9778: 9767: 9759: 9753: 9752: 9750: 9748: 9739:. Archived from 9726: 9720: 9719: 9717: 9715: 9695: 9689: 9688: 9686: 9684: 9678: 9667: 9659: 9653: 9652: 9650: 9648: 9629: 9623: 9622: 9620: 9618: 9598: 9592: 9591: 9589: 9587: 9578:. Archived from 9565: 9559: 9558: 9552: 9550: 9535: 9529: 9528: 9526: 9524: 9518: 9507: 9499: 9493: 9492: 9490: 9488: 9482: 9471: 9463: 9457: 9456: 9454: 9452: 9447:on 27 March 2014 9433: 9427: 9426: 9424: 9422: 9417:on 27 March 2014 9403: 9394: 9393: 9391: 9389: 9383: 9372: 9364: 9358: 9357: 9355: 9353: 9347: 9336: 9328: 9322: 9321: 9319: 9317: 9297: 9291: 9290: 9288: 9286: 9266: 9260: 9259: 9257: 9255: 9234: 9228: 9227: 9225: 9223: 9198: 9192: 9191: 9189: 9187: 9165: 9159: 9158: 9156: 9154: 9135: 9129: 9128: 9126: 9124: 9099: 9093: 9092: 9090: 9088: 9067: 9061: 9060: 9058: 9056: 9045:Nature News Blog 9036: 9030: 9029: 9027: 9025: 9014: 9006: 8997: 8996: 8994: 8992: 8976: 8970: 8969: 8967: 8965: 8928: 8922: 8921: 8919: 8917: 8912:. 9 October 2012 8900: 8894: 8893: 8888: 8886: 8873: 8839: 8833: 8832: 8830: 8828: 8795: 8789: 8788: 8786: 8784: 8771: 8741: 8735: 8734: 8732: 8730: 8724: 8710: 8702: 8685: 8684: 8682: 8680: 8674: 8663: 8655: 8649: 8648: 8646: 8644: 8624: 8618: 8617: 8615: 8613: 8591: 8585: 8584: 8582: 8580: 8571:. 2 March 2007. 8559: 8553: 8552: 8550: 8548: 8542: 8519: 8510: 8504: 8503: 8501: 8499: 8477: 8471: 8470: 8468: 8466: 8450: 8441: 8440: 8438: 8436: 8430: 8414: 8408: 8407: 8405: 8403: 8397: 8383: 8375: 8356: 8355: 8353: 8351: 8332: 8326: 8325: 8315: 8305: 8281: 8275: 8274: 8272: 8270: 8248: 8242: 8241: 8239: 8237: 8218: 8212: 8211: 8209: 8207: 8192: 8186: 8185: 8183: 8181: 8172:. Archived from 8166: 8160: 8159: 8136:Health Educ. Res 8131: 8122: 8121: 8119: 8117: 8098: 8092: 8091: 8089: 8087: 8068: 8062: 8061: 8059: 8057: 8051: 8044: 8036: 8030: 8029: 8027: 8025: 8019: 7996: 7987: 7981: 7980: 7978: 7976: 7957: 7951: 7950: 7948: 7946: 7930: 7917: 7916: 7888: 7882: 7881: 7879: 7877: 7851: 7841: 7835: 7834: 7832: 7830: 7824: 7807: 7796: 7787: 7786: 7784: 7782: 7767: 7738: 7737: 7735: 7733: 7727: 7716: 7708: 7683: 7682: 7680: 7678: 7659: 7636: 7635: 7625: 7607: 7598: 7592: 7591: 7589: 7587: 7567: 7558: 7557: 7555: 7553: 7534: 7525: 7524: 7522: 7520: 7498: 7487: 7486: 7484: 7482: 7476: 7469: 7461: 7455: 7454: 7452: 7450: 7434: 7428: 7427: 7425: 7423: 7404: 7398: 7397: 7395: 7393: 7365: 7359: 7358: 7348: 7338: 7306: 7300: 7299: 7297: 7295: 7273: 7267: 7266: 7261: 7259: 7253: 7239: 7233:Kinder M (ed.). 7230: 7224: 7223: 7213: 7203: 7179: 7170: 7169: 7159: 7149: 7125: 7116: 7115: 7113: 7111: 7089: 7078: 7077: 7075: 7073: 7054: 7045: 7044: 7042: 7040: 7018: 7009: 7008: 7006: 7004: 6982: 6976: 6975: 6973: 6971: 6950: 6944: 6943: 6941: 6939: 6920: 6914: 6913: 6911: 6909: 6887: 6881: 6880: 6878: 6876: 6865: 6859: 6858: 6856: 6854: 6832: 6826: 6825: 6823: 6821: 6799: 6793: 6792: 6790: 6788: 6768: 6762: 6761: 6759: 6757: 6738: 6732: 6731: 6729: 6727: 6705: 6699: 6698: 6688: 6664: 6658: 6657: 6655: 6653: 6631: 6625: 6624: 6614: 6582: 6567: 6566: 6556: 6524: 6515: 6514: 6504: 6472: 6466: 6465: 6455: 6438:(2–3): 183–188. 6423: 6417: 6416: 6406: 6374: 6363: 6362: 6360: 6358: 6338: 6327: 6326: 6324: 6322: 6316: 6301: 6283: 6274: 6268: 6267: 6257: 6233: 6227: 6226: 6216: 6206: 6182: 6176: 6175: 6173: 6171: 6162:. Archived from 6149: 6143: 6142: 6140: 6138: 6119: 6113: 6112: 6110: 6108: 6099:. Archived from 6093: 6087: 6086: 6084: 6082: 6066: 6045: 6044: 6042: 6040: 6034: 6019: 5993: 5984: 5971: 5970: 5960: 5950: 5926: 5920: 5919: 5917: 5915: 5896: 5890: 5889: 5879: 5847: 5841: 5840: 5838: 5836: 5821: 5815: 5814: 5804: 5786: 5762: 5756: 5755: 5745: 5713: 5707: 5706: 5704: 5702: 5696: 5665: 5659:Fine PE (1993). 5656: 5650: 5649: 5647: 5645: 5629: 5623: 5622: 5620: 5618: 5599: 5593: 5592: 5582: 5565:(8): 1113–1123. 5550: 5544: 5543: 5541: 5539: 5533: 5518: 5492: 5483: 5477: 5476: 5474: 5472: 5466: 5451: 5433: 5424: 5418: 5417: 5415: 5413: 5394: 5385: 5384: 5382: 5380: 5365: 5359: 5358: 5356: 5354: 5339: 5333: 5332: 5304: 5295: 5294: 5284: 5274: 5250: 5244: 5243: 5241: 5239: 5225: 5206: 5205: 5203: 5201: 5195: 5176: 5167: 5161: 5160: 5158: 5156: 5137: 5131: 5130: 5128: 5126: 5120: 5091: 5080: 5074: 5073: 5071: 5069: 5063: 5043:MMWR Supplements 5040: 5031: 5025: 5024: 5022: 5020: 5014: 4991: 4983: 4977: 4976: 4940: 4934: 4933: 4923: 4891: 4882: 4881: 4879: 4877: 4858: 4852: 4851: 4849: 4847: 4832: 4826: 4825: 4815: 4783: 4774: 4773: 4771: 4769: 4760:. 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2531: 2513: 2508: 2490: 2485: 2467: 2462: 2444: 2439: 2421: 2416: 2398: 2393: 2375: 2370: 2352: 2347: 2329: 2324: 2306: 2301: 2283: 2278: 2260: 2255: 2237: 2232: 2214: 2209: 2191: 2186: 2168: 2163: 2145: 2140: 2122: 2117: 2099: 2095: 2090: 2072: 2067: 2049: 2045: 2040: 2022: 2017: 1999: 1995: 1990: 1931: 1930: 1877:Papua New Guinea 1850:Syrian Civil War 1730: 1688: 1635: 1472: 1410: 1404: 1398: 1392: 1372: 1341: 1326: 1320: 1314: 1308: 1302: 1296: 1288: 1282: 1276: 1270: 1264: 1258: 1252: 1246: 1200: 1132: 700: 699: 691: 687: 542: 487: 483: 479: 474: 460: 444: 361: 357: 352: 334: 333:US$ 0.15 to 0.20 164: 160: 156: 129:contact immunity 21: 14008: 14007: 14003: 14002: 14001: 13999: 13998: 13997: 13963: 13962: 13961: 13956: 13793: 13676: 13614: 13597:Swansea measles 13549:Bolivian dengue 13477: 13469: 13458:Indian smallpox 13428:Croydon typhoid 13398: 13290: 13231: 13217: 13152: 13093: 13086: 13057:Plague of Amwas 13030: 13023: 13012:Antonine Plague 12999: 12972: 12959: 12946: 12916: 12911: 12849: 12785: 12751: 12741: 12720: 12696: 12686: 12622: 12616: 12569: 12563: 12539: 12533: 12528: 12487: 12484: 12479: 12430: 12428:Further reading 12425: 12424: 12416: 12410: 12409: 12398: 12388: 12386: 12382: 12378: 12377: 12373: 12365: 12359: 12358: 12354: 12345: 12344: 12340: 12327: 12326: 12322: 12314: 12310: 12309: 12300: 12292: 12288: 12287: 12280: 12271: 12270: 12266: 12256: 12254: 12245: 12244: 12240: 12230: 12228: 12218: 12214: 12204: 12202: 12187: 12183: 12173: 12171: 12162: 12161: 12154: 12144: 12142: 12127: 12123: 12113: 12111: 12102: 12101: 12097: 12072: 12071: 12067: 12057: 12055: 12043: 12039: 12030: 12029: 12025: 12013: 12009: 12008: 12004: 11994: 11992: 11987: 11986: 11982: 11972: 11970: 11965: 11964: 11960: 11950: 11948: 11941: 11937: 11927: 11925: 11918: 11914: 11904: 11902: 11895: 11891: 11882: 11881: 11877: 11832: 11825: 11815: 11813: 11806: 11799: 11789: 11787: 11782: 11781: 11777: 11768: 11767: 11763: 11755: 11751: 11750: 11746: 11736: 11734: 11727: 11723: 11714: 11713: 11709: 11699: 11697: 11696:. 23 April 2024 11688: 11687: 11662: 11652: 11650: 11641: 11640: 11633: 11623: 11621: 11606: 11602: 11592: 11590: 11577: 11576: 11572: 11559: 11558: 11554: 11544: 11542: 11531: 11527: 11517: 11515: 11498: 11494: 11463:(15): 538–544. 11449: 11442: 11387: 11383: 11373: 11371: 11354: 11350: 11340: 11338: 11329: 11328: 11324: 11314: 11312: 11297: 11293: 11283: 11281: 11266: 11262: 11252: 11250: 11237: 11236: 11232: 11222: 11220: 11207: 11206: 11202: 11192: 11190: 11179: 11175: 11165: 11163: 11148: 11144: 11134: 11132: 11117: 11113: 11103: 11101: 11084: 11080: 11070: 11068: 11064: 11053: 11049: 11048: 11044: 11034: 11032: 11015: 11011: 11001: 10999: 10983: 10982: 10978: 10968: 10966: 10951:(24 May 2019). 10946: 10939: 10929: 10927: 10896: 10892: 10882: 10880: 10876: 10865: 10861: 10860: 10856: 10825:(24): 690–694. 10811: 10807: 10797: 10795: 10779: 10778: 10774: 10764: 10762: 10758: 10754: 10753: 10749: 10739: 10737: 10724: 10723: 10719: 10709: 10707: 10703: 10692: 10688: 10687: 10666: 10656: 10654: 10645: 10644: 10640: 10609:(29): 642–646. 10595: 10588: 10557:(33): 729–733. 10543: 10539: 10531: 10527: 10526: 10522: 10477: 10473: 10463: 10461: 10457: 10450: 10446: 10445: 10438: 10428: 10426: 10413: 10412: 10408: 10398: 10396: 10392: 10378: 10374: 10373: 10369: 10359: 10357: 10344: 10343: 10336: 10326: 10324: 10311: 10310: 10306: 10296: 10294: 10279: 10275: 10230: 10221: 10211: 10209: 10196: 10195: 10188: 10157:(10): 300–305. 10143: 10139: 10129: 10127: 10116: 10112: 10102: 10100: 10087: 10086: 10082: 10033: 10029: 9984: 9977: 9967: 9965: 9942: 9938: 9893: 9889: 9879: 9877: 9873: 9843:(32): 854–858. 9832: 9826: 9822: 9812: 9810: 9797: 9796: 9792: 9782: 9780: 9776: 9765: 9761: 9760: 9756: 9746: 9744: 9728: 9727: 9723: 9713: 9711: 9696: 9692: 9682: 9680: 9676: 9665: 9661: 9660: 9656: 9646: 9644: 9631: 9630: 9626: 9616: 9614: 9599: 9595: 9585: 9583: 9567: 9566: 9562: 9548: 9546: 9537: 9536: 9532: 9522: 9520: 9516: 9505: 9501: 9500: 9496: 9486: 9484: 9480: 9469: 9465: 9464: 9460: 9450: 9448: 9435: 9434: 9430: 9420: 9418: 9405: 9404: 9397: 9387: 9385: 9381: 9370: 9366: 9365: 9361: 9351: 9349: 9345: 9334: 9330: 9329: 9325: 9315: 9313: 9298: 9294: 9284: 9282: 9267: 9263: 9253: 9251: 9243:BBC News Online 9236: 9235: 9231: 9221: 9219: 9204:(7 June 2013). 9199: 9195: 9185: 9183: 9175:Times of Israel 9166: 9162: 9152: 9150: 9137: 9136: 9132: 9122: 9120: 9100: 9096: 9086: 9084: 9076:BBC News Online 9069: 9068: 9064: 9054: 9052: 9037: 9033: 9023: 9021: 9012: 9008: 9007: 9000: 8990: 8988: 8977: 8973: 8963: 8961: 8929: 8925: 8915: 8913: 8902: 8901: 8897: 8884: 8882: 8840: 8836: 8826: 8824: 8796: 8792: 8782: 8780: 8742: 8738: 8728: 8726: 8722: 8708: 8704: 8703: 8688: 8678: 8676: 8672: 8661: 8657: 8656: 8652: 8642: 8640: 8633:BBC News Online 8625: 8621: 8611: 8609: 8593: 8592: 8588: 8578: 8576: 8568:BBC News Online 8561: 8560: 8556: 8546: 8544: 8540: 8517: 8511: 8507: 8497: 8495: 8478: 8474: 8464: 8462: 8451: 8444: 8434: 8432: 8428: 8416: 8415: 8411: 8401: 8399: 8398:on 4 March 2016 8395: 8381: 8377: 8376: 8359: 8349: 8347: 8342:. 11 May 2005. 8334: 8333: 8329: 8282: 8278: 8268: 8266: 8265:on 19 June 2007 8250: 8249: 8245: 8235: 8233: 8220: 8219: 8215: 8205: 8203: 8194: 8193: 8189: 8179: 8177: 8168: 8167: 8163: 8132: 8125: 8115: 8113: 8100: 8099: 8095: 8085: 8083: 8082:on 29 July 2007 8070: 8069: 8065: 8055: 8053: 8049: 8042: 8038: 8037: 8033: 8023: 8021: 8017: 8005:(39): 720–722. 7994: 7988: 7984: 7974: 7972: 7959: 7958: 7954: 7944: 7942: 7931: 7920: 7889: 7885: 7875: 7873: 7849: 7842: 7838: 7828: 7826: 7822: 7816: 7805: 7797: 7790: 7780: 7778: 7777:. 23 April 2024 7769: 7768: 7741: 7731: 7729: 7725: 7714: 7710: 7709: 7686: 7676: 7674: 7661: 7660: 7639: 7605: 7599: 7595: 7585: 7583: 7570:Lee JW (1995). 7568: 7561: 7551: 7549: 7536: 7535: 7528: 7518: 7516: 7500: 7499: 7490: 7480: 7478: 7474: 7467: 7463: 7462: 7458: 7448: 7446: 7435: 7431: 7421: 7419: 7406: 7405: 7401: 7391: 7389: 7366: 7362: 7321:(7): e0180608. 7307: 7303: 7293: 7291: 7275: 7274: 7270: 7257: 7255: 7251: 7237: 7231: 7227: 7180: 7173: 7126: 7119: 7109: 7107: 7091: 7090: 7081: 7071: 7069: 7056: 7055: 7048: 7038: 7036: 7020: 7019: 7012: 7002: 7000: 6983: 6979: 6969: 6967: 6952: 6951: 6947: 6937: 6935: 6922: 6921: 6917: 6907: 6905: 6888: 6884: 6874: 6872: 6867: 6866: 6862: 6852: 6850: 6833: 6829: 6819: 6817: 6809:BBC News Online 6800: 6796: 6786: 6784: 6769: 6765: 6755: 6753: 6746:BBC News Online 6740: 6739: 6735: 6725: 6723: 6706: 6702: 6665: 6661: 6651: 6649: 6632: 6628: 6583: 6570: 6525: 6518: 6473: 6469: 6424: 6420: 6389:(6): 978a–978. 6375: 6366: 6356: 6354: 6339: 6330: 6320: 6318: 6314: 6292:(23): 640–646. 6281: 6275: 6271: 6234: 6230: 6183: 6179: 6169: 6167: 6151: 6150: 6146: 6136: 6134: 6123:"Poliomyelitis" 6121: 6120: 6116: 6106: 6104: 6095: 6094: 6090: 6080: 6078: 6067: 6048: 6038: 6036: 6032: 6002:(13): 312–318. 5991: 5985: 5974: 5927: 5923: 5913: 5911: 5898: 5897: 5893: 5848: 5844: 5834: 5832: 5822: 5818: 5763: 5759: 5714: 5710: 5700: 5698: 5694: 5663: 5657: 5653: 5643: 5641: 5630: 5626: 5616: 5614: 5613:on 24 June 2018 5601: 5600: 5596: 5551: 5547: 5537: 5535: 5531: 5490: 5484: 5480: 5470: 5468: 5464: 5442:(33): 859–863. 5431: 5425: 5421: 5411: 5409: 5396: 5395: 5388: 5378: 5376: 5366: 5362: 5352: 5350: 5349:. 12 April 2024 5341: 5340: 5336: 5305: 5298: 5251: 5247: 5237: 5235: 5227: 5226: 5209: 5199: 5197: 5193: 5174: 5168: 5164: 5154: 5152: 5139: 5138: 5134: 5124: 5122: 5118: 5112: 5089: 5081: 5077: 5067: 5065: 5061: 5038: 5032: 5028: 5018: 5016: 5012: 4989: 4985: 4984: 4980: 4941: 4937: 4892: 4885: 4875: 4873: 4860: 4859: 4855: 4845: 4843: 4834: 4833: 4829: 4798:(19): 441–446. 4784: 4777: 4767: 4765: 4756: 4755: 4748: 4738: 4736: 4721: 4712: 4702: 4700: 4693:BBC News Online 4685: 4681: 4671: 4669: 4656: 4655: 4651: 4641: 4639: 4638:on 8 March 2016 4626: 4625: 4621: 4616: 4564: 4562: 4550: 4547: 4528: 4522: 4498: 4497: 4473: 4468: 4450: 4445: 4427: 4422: 4404: 4399: 4381: 4376: 4358: 4353: 4335: 4330: 4312: 4307: 4289: 4284: 4266: 4261: 4243: 4238: 4220: 4215: 4197: 4192: 4174: 4169: 4151: 4150: 4147: 4142: 4138: 4122: 4117: 4099: 4094: 4076: 4071: 4053: 4048: 4028: 4023: 4021: 4019: 4014: 4005: 3987: 3954: 3953: 3929: 3924: 3906: 3901: 3883: 3878: 3860: 3855: 3837: 3832: 3814: 3809: 3791: 3786: 3768: 3763: 3745: 3740: 3722: 3717: 3699: 3698: 3695: 3690: 3686: 3670: 3665: 3647: 3642: 3624: 3619: 3601: 3596: 3578: 3573: 3555: 3550: 3532: 3527: 3509: 3504: 3486: 3481: 3463: 3458: 3440: 3435: 3417: 3416: 3413: 3408: 3404: 3388: 3383: 3365: 3360: 3340: 3335: 3333: 3331: 3326: 3317: 3299: 3274: 3273: 3249: 3244: 3226: 3221: 3203: 3198: 3180: 3175: 3157: 3152: 3134: 3129: 3111: 3106: 3088: 3083: 3065: 3060: 3042: 3037: 3019: 3014: 2996: 2991: 2973: 2968: 2950: 2945: 2927: 2922: 2904: 2899: 2881: 2876: 2858: 2853: 2835: 2830: 2812: 2807: 2789: 2784: 2766: 2761: 2743: 2742: 2739: 2734: 2730: 2722:Dem. Rep. Congo 2714: 2709: 2691: 2690: 2687: 2686: 2683: 2679: 2678: 2676: 2672: 2670: 2667: 2666: 2653: 2648: 2628: 2623: 2621: 2619: 2614: 2605: 2587: 2566: 2559: 2558: 2534: 2529: 2511: 2506: 2488: 2483: 2465: 2460: 2442: 2437: 2419: 2414: 2396: 2391: 2373: 2368: 2350: 2345: 2327: 2322: 2304: 2299: 2281: 2276: 2258: 2253: 2235: 2230: 2212: 2207: 2189: 2184: 2166: 2161: 2143: 2138: 2128:Dem. Rep. Congo 2120: 2115: 2097: 2096: 2093: 2088: 2070: 2065: 2047: 2046: 2043: 2038: 2020: 2015: 1997: 1996: 1993: 1988: 1968: 1963: 1961: 1959: 1954: 1945: 1927: 1805: 1728: 1686: 1642: 1633: 1552:42, Angola 29, 1487: 1470: 1412: 1408: 1406: 1402: 1400: 1396: 1394: 1390: 1370: 1339: 1334: 1328: 1324: 1322: 1318: 1316: 1312: 1310: 1306: 1304: 1300: 1298: 1294: 1290: 1286: 1284: 1280: 1278: 1274: 1272: 1268: 1266: 1262: 1260: 1256: 1254: 1250: 1234: 1198: 1141:, August 1991. 1130: 1117:, and the U.S. 1103: 1076:Ciro de Quadros 1043: 698: 689: 685: 681: 593: 591:Antivaccination 587: 540: 516: 499: 491:clinical trials 485: 481: 477: 472: 468: 467: 466: 465: 464: 461: 452: 451: 450: 448: 445: 434: 393: 380:fractional-dose 359: 355: 350: 332: 309: 243: 186: 162: 158: 154: 141:immunodeficient 35: 28: 23: 22: 15: 12: 11: 5: 14006: 13996: 13995: 13990: 13985: 13980: 13975: 13958: 13957: 13955: 13954: 13948: 13942: 13932: 13926: 13925:(1981–present) 13920: 13914: 13908: 13902: 13896: 13890: 13884: 13878: 13872: 13866: 13860: 13854: 13848: 13842: 13836: 13830: 13824: 13818: 13811: 13809: 13803: 13802: 13799: 13798: 13795: 13794: 13792: 13791: 13790: 13789: 13778: 13777:(2023–present) 13772: 13769:Jamaica dengue 13766: 13760: 13754: 13748: 13742: 13736: 13730: 13724: 13718: 13712: 13706: 13700: 13694: 13688: 13682: 13674: 13668: 13665:Yemeni cholera 13662: 13656: 13650: 13644: 13638: 13632: 13626: 13620: 13616:DR Congo Ebola 13612: 13606: 13600: 13594: 13588: 13582: 13576: 13570: 13564: 13558: 13552: 13546: 13540: 13534: 13528: 13522: 13516: 13510: 13504: 13498: 13492: 13485: 13483: 13479: 13478: 13476: 13475: 13467: 13461: 13455: 13449: 13443: 13437: 13431: 13425: 13419: 13413: 13406: 13404: 13400: 13399: 13397: 13396: 13390: 13384: 13378: 13372: 13366: 13360: 13354: 13348: 13342: 13336: 13330: 13324: 13321:Maltese plague 13318: 13315:Ottoman plague 13311: 13309: 13302: 13296: 13295: 13292: 13291: 13289: 13288: 13282: 13276: 13273:Persian Plague 13270: 13267:Russian plague 13264: 13258: 13252: 13246: 13239: 13237: 13233: 13232: 13230: 13229: 13223: 13219:Maltese plague 13215: 13209: 13203: 13200:Maltese plague 13197: 13191: 13185: 13179: 13176:Italian plague 13173: 13170:Maltese plague 13167: 13160: 13158: 13154: 13153: 13151: 13150: 13148: 13142: 13139:Maltese plague 13136: 13130: 13124: 13118: 13112: 13105: 13103: 13096: 13088: 13087: 13085: 13084: 13078: 13072: 13066: 13060: 13054: 13048: 13042: 13035: 13033: 13025: 13024: 13022: 13021: 13015: 13009: 13003: 12993:Hittite plague 12989: 12987: 12978: 12974: 12973: 12971: 12970: 12964: 12961: 12960: 12945: 12944: 12937: 12930: 12922: 12913: 12912: 12910: 12909: 12904: 12899: 12894: 12893: 12892: 12887: 12877: 12872: 12867: 12861: 12859: 12858:Related topics 12855: 12854: 12851: 12850: 12848: 12847: 12846: 12845: 12842:The Final Inch 12838: 12826: 12825: 12824: 12819: 12811: 12810: 12809: 12804: 12793: 12791: 12787: 12786: 12784: 12783: 12778: 12773: 12768: 12762: 12760: 12753: 12747: 12746: 12743: 12742: 12740: 12739: 12734: 12728: 12726: 12722: 12721: 12719: 12718: 12707: 12705: 12698: 12695:Eradication of 12692: 12691: 12688: 12687: 12685: 12684: 12679: 12674: 12669: 12667:Onchocerciasis 12664: 12659: 12654: 12653: 12652: 12647: 12637: 12632: 12626: 12624: 12618: 12617: 12615: 12614: 12604: 12594: 12584: 12577:Dracunculiasis 12573: 12571: 12565: 12564: 12562: 12561: 12550: 12548: 12541: 12540:human diseases 12538:Eradication of 12535: 12534: 12527: 12526: 12519: 12512: 12504: 12498: 12497: 12483: 12482:External links 12480: 12478: 12477: 12431: 12429: 12426: 12423: 12422: 12396: 12371: 12352: 12338: 12320: 12298: 12278: 12264: 12238: 12212: 12181: 12152: 12121: 12095: 12065: 12037: 12023: 12002: 11980: 11958: 11935: 11912: 11889: 11875: 11823: 11797: 11775: 11761: 11744: 11721: 11707: 11660: 11631: 11600: 11570: 11552: 11525: 11492: 11440: 11381: 11348: 11322: 11291: 11260: 11230: 11200: 11173: 11142: 11111: 11078: 11042: 11009: 10976: 10937: 10890: 10854: 10805: 10772: 10747: 10717: 10664: 10638: 10586: 10537: 10520: 10471: 10436: 10406: 10367: 10334: 10304: 10273: 10244:(9): 225–230. 10219: 10186: 10137: 10126:on 25 May 2017 10110: 10080: 10027: 9998:(8): 253–256. 9975: 9936: 9887: 9820: 9790: 9754: 9721: 9690: 9654: 9624: 9593: 9582:on 15 May 2016 9560: 9530: 9494: 9458: 9428: 9395: 9359: 9323: 9292: 9261: 9229: 9193: 9160: 9130: 9094: 9062: 9031: 8998: 8971: 8923: 8895: 8834: 8790: 8736: 8686: 8675:on 18 May 2013 8650: 8619: 8586: 8554: 8505: 8472: 8442: 8431:on 11 May 2007 8409: 8357: 8327: 8276: 8243: 8232:on 16 May 2010 8213: 8187: 8161: 8142:(1): 110–111. 8123: 8093: 8063: 8031: 7982: 7952: 7918: 7883: 7836: 7814: 7788: 7739: 7684: 7637: 7616:(4): 268–273. 7593: 7559: 7526: 7488: 7456: 7429: 7399: 7360: 7301: 7268: 7225: 7171: 7117: 7079: 7046: 7010: 6977: 6945: 6915: 6882: 6860: 6827: 6794: 6763: 6733: 6700: 6679:(2): 153–155. 6659: 6626: 6568: 6516: 6467: 6418: 6364: 6328: 6269: 6228: 6197:(9): 801–803. 6177: 6144: 6114: 6103:on 6 July 2010 6088: 6077:on 8 June 2006 6046: 5972: 5921: 5891: 5842: 5816: 5757: 5708: 5674:(2): 265–302. 5651: 5624: 5594: 5545: 5478: 5419: 5386: 5360: 5334: 5315:(6): 672–692. 5296: 5245: 5207: 5162: 5132: 5110: 5075: 5026: 4978: 4935: 4906:(9): 683–688. 4883: 4853: 4827: 4775: 4746: 4710: 4679: 4649: 4618: 4617: 4615: 4612: 4611: 4610: 4605: 4600: 4595: 4590: 4585: 4581:The Final Inch 4577: 4572: 4560: 4546: 4543: 4527: 4524: 4510:Southeast Asia 4494: 4493: 4491: 4489: 4486: 4483: 4477: 4476: 4471: 4466: 4463: 4460: 4454: 4453: 4448: 4443: 4440: 4437: 4431: 4430: 4425: 4420: 4417: 4414: 4408: 4407: 4402: 4397: 4394: 4391: 4385: 4384: 4379: 4374: 4371: 4368: 4362: 4361: 4356: 4351: 4348: 4345: 4339: 4338: 4333: 4328: 4325: 4322: 4316: 4315: 4310: 4305: 4302: 4299: 4293: 4292: 4287: 4282: 4279: 4276: 4270: 4269: 4264: 4259: 4256: 4253: 4247: 4246: 4241: 4236: 4233: 4230: 4224: 4223: 4218: 4213: 4210: 4207: 4201: 4200: 4195: 4190: 4187: 4184: 4178: 4177: 4172: 4167: 4164: 4161: 4155: 4154: 4145: 4140: 4135: 4132: 4126: 4125: 4120: 4115: 4112: 4109: 4103: 4102: 4097: 4092: 4089: 4086: 4080: 4079: 4074: 4069: 4066: 4063: 4057: 4056: 4051: 4046: 4043: 4040: 4034: 4033: 4030: 4025: 4016: 4011: 4007: 4006: 3994: 3989: 3988: 3986: 3983: 3950: 3949: 3947: 3945: 3942: 3939: 3933: 3932: 3927: 3922: 3919: 3916: 3910: 3909: 3904: 3899: 3896: 3893: 3887: 3886: 3881: 3876: 3873: 3870: 3864: 3863: 3858: 3853: 3850: 3847: 3841: 3840: 3835: 3830: 3827: 3824: 3818: 3817: 3812: 3807: 3804: 3801: 3795: 3794: 3789: 3784: 3781: 3778: 3772: 3771: 3766: 3761: 3758: 3755: 3749: 3748: 3743: 3738: 3735: 3732: 3726: 3725: 3720: 3715: 3712: 3709: 3703: 3702: 3693: 3688: 3683: 3680: 3674: 3673: 3668: 3663: 3660: 3657: 3651: 3650: 3645: 3640: 3637: 3634: 3628: 3627: 3622: 3617: 3614: 3611: 3605: 3604: 3599: 3594: 3591: 3588: 3582: 3581: 3576: 3571: 3568: 3565: 3559: 3558: 3553: 3548: 3545: 3542: 3536: 3535: 3530: 3525: 3522: 3519: 3513: 3512: 3507: 3502: 3499: 3496: 3490: 3489: 3484: 3479: 3476: 3473: 3467: 3466: 3461: 3456: 3453: 3450: 3444: 3443: 3438: 3433: 3430: 3427: 3421: 3420: 3411: 3406: 3401: 3398: 3392: 3391: 3386: 3381: 3378: 3375: 3369: 3368: 3363: 3358: 3355: 3352: 3346: 3345: 3342: 3337: 3328: 3323: 3319: 3318: 3306: 3301: 3300: 3298: 3295: 3270: 3269: 3267: 3265: 3262: 3259: 3253: 3252: 3247: 3242: 3239: 3236: 3230: 3229: 3224: 3219: 3216: 3213: 3207: 3206: 3201: 3196: 3193: 3190: 3184: 3183: 3178: 3173: 3170: 3167: 3161: 3160: 3155: 3150: 3147: 3144: 3138: 3137: 3132: 3127: 3124: 3121: 3115: 3114: 3109: 3104: 3101: 3098: 3092: 3091: 3086: 3081: 3078: 3075: 3069: 3068: 3063: 3058: 3055: 3052: 3046: 3045: 3040: 3035: 3032: 3029: 3023: 3022: 3017: 3012: 3009: 3006: 3000: 2999: 2994: 2989: 2986: 2983: 2977: 2976: 2971: 2966: 2963: 2960: 2954: 2953: 2948: 2943: 2940: 2937: 2931: 2930: 2925: 2920: 2917: 2914: 2908: 2907: 2902: 2897: 2894: 2891: 2885: 2884: 2879: 2874: 2871: 2868: 2862: 2861: 2856: 2851: 2848: 2845: 2839: 2838: 2833: 2828: 2825: 2822: 2816: 2815: 2810: 2805: 2802: 2799: 2793: 2792: 2787: 2782: 2779: 2776: 2770: 2769: 2764: 2759: 2756: 2753: 2747: 2746: 2737: 2732: 2727: 2724: 2718: 2717: 2712: 2707: 2704: 2701: 2695: 2694: 2681: 2674: 2668: 2663: 2657: 2656: 2651: 2646: 2643: 2640: 2634: 2633: 2630: 2625: 2616: 2611: 2607: 2606: 2594: 2589: 2588: 2586: 2583: 2555: 2554: 2552: 2550: 2547: 2544: 2538: 2537: 2532: 2527: 2524: 2521: 2515: 2514: 2509: 2504: 2501: 2498: 2492: 2491: 2486: 2481: 2478: 2475: 2469: 2468: 2463: 2458: 2455: 2452: 2446: 2445: 2440: 2435: 2432: 2429: 2423: 2422: 2417: 2412: 2409: 2406: 2400: 2399: 2394: 2389: 2386: 2383: 2377: 2376: 2371: 2366: 2363: 2360: 2354: 2353: 2348: 2343: 2340: 2337: 2331: 2330: 2325: 2320: 2317: 2314: 2308: 2307: 2302: 2297: 2294: 2291: 2285: 2284: 2279: 2274: 2271: 2268: 2262: 2261: 2256: 2251: 2248: 2245: 2239: 2238: 2233: 2228: 2225: 2222: 2216: 2215: 2210: 2205: 2202: 2199: 2193: 2192: 2187: 2182: 2179: 2176: 2170: 2169: 2164: 2159: 2156: 2153: 2147: 2146: 2141: 2136: 2133: 2130: 2124: 2123: 2118: 2113: 2110: 2107: 2101: 2100: 2091: 2086: 2083: 2080: 2074: 2073: 2068: 2063: 2060: 2057: 2051: 2050: 2041: 2036: 2033: 2030: 2024: 2023: 2018: 2013: 2010: 2007: 2001: 2000: 1991: 1986: 1983: 1980: 1974: 1973: 1970: 1965: 1956: 1951: 1947: 1946: 1934: 1929: 1928: 1926: 1923: 1804: 1801: 1700:Horn of Africa 1692:Central Africa 1641: 1638: 1592:with 8 cases, 1548:64, Sudan 45, 1515:Umaru Yar'Adua 1511:Turai Yar'Adua 1486: 1483: 1407: 1401: 1395: 1389: 1331: 1330: 1323: 1317: 1311: 1305: 1299: 1293: 1291: 1289: 2.1–2.55 1285: 1283: 1.65–2.1 1279: 1277: 1.2–1.65 1273: 1271: 0.75–1.2 1267: 1265: 0.3–0.75 1261: 1255: 1249: 1244: 1233: 1230: 1102: 1099: 1093:, in the book 1059:Czechoslovakia 1042: 1039: 1036: 1035: 1032: 1029: 1025: 1024: 1021: 1018: 1014: 1013: 1010: 1007: 1003: 1002: 999: 996: 990: 989: 986: 983: 979: 978: 975: 972: 968: 967: 964: 961: 957: 956: 953: 950: 946: 945: 942: 939: 933: 932: 929: 926: 922: 921: 918: 915: 911: 910: 907: 904: 900: 899: 896: 893: 889: 888: 885: 882: 876: 875: 871: 870: 867: 864: 858: 857: 853: 852: 849: 846: 840: 839: 835: 834: 831: 828: 822: 821: 817: 816: 813: 810: 806: 805: 801: 800: 797: 794: 788: 787: 783: 782: 779: 776: 772: 771: 767: 766: 763: 760: 754: 753: 749: 748: 745: 742: 736: 735: 731: 730: 727: 724: 718: 717: 714: 711: 707: 706: 697: 694: 680: 677: 586: 583: 545:seroconversion 515: 512: 498: 495: 462: 455: 454: 453: 446: 439: 438: 437: 436: 435: 433: 430: 392: 389: 308: 305: 304: 303: 300: 296: 268: 265: 242: 239: 215: 214: 211: 204: 193: 185: 182: 108:in ruminants. 104:in humans and 26: 9: 6: 4: 3: 2: 14005: 13994: 13991: 13989: 13986: 13984: 13981: 13979: 13976: 13974: 13971: 13970: 13968: 13952: 13949: 13946: 13943: 13937:(2019–present 13936: 13933: 13930: 13927: 13924: 13921: 13918: 13915: 13912: 13911:Hong Kong flu 13909: 13906: 13903: 13900: 13897: 13894: 13891: 13888: 13885: 13882: 13879: 13876: 13873: 13870: 13867: 13864: 13861: 13858: 13855: 13852: 13849: 13846: 13843: 13840: 13837: 13834: 13831: 13828: 13825: 13822: 13819: 13816: 13813: 13812: 13810: 13808: 13804: 13787: 13784: 13783: 13782: 13779: 13776: 13773: 13770: 13767: 13764: 13761: 13758: 13755: 13752: 13749: 13746: 13743: 13740: 13739:Tonga measles 13737: 13734: 13731: 13728: 13725: 13722: 13719: 13716: 13713: 13710: 13709:Samoa measles 13707: 13704: 13701: 13698: 13695: 13692: 13689: 13686: 13683: 13679: 13675: 13672: 13669: 13666: 13663: 13660: 13657: 13654: 13651: 13648: 13645: 13642: 13639: 13636: 13633: 13630: 13627: 13624: 13621: 13617: 13613: 13610: 13607: 13604: 13601: 13598: 13595: 13592: 13589: 13586: 13583: 13580: 13577: 13574: 13571: 13568: 13567:Haiti cholera 13565: 13562: 13559: 13556: 13553: 13550: 13547: 13544: 13541: 13538: 13535: 13532: 13531:Iraqi cholera 13529: 13526: 13523: 13520: 13517: 13514: 13513:Indian dengue 13511: 13508: 13505: 13502: 13499: 13496: 13493: 13490: 13487: 13486: 13484: 13480: 13472: 13468: 13465: 13462: 13459: 13456: 13453: 13450: 13447: 13444: 13441: 13438: 13435: 13432: 13429: 13426: 13423: 13420: 13417: 13414: 13411: 13408: 13407: 13405: 13401: 13394: 13391: 13388: 13385: 13382: 13379: 13376: 13373: 13370: 13369:Guam smallpox 13367: 13364: 13361: 13358: 13355: 13352: 13349: 13346: 13343: 13340: 13337: 13334: 13331: 13328: 13325: 13322: 13319: 13316: 13313: 13312: 13310: 13306: 13303: 13301: 13297: 13286: 13283: 13280: 13277: 13274: 13271: 13268: 13265: 13262: 13259: 13256: 13253: 13250: 13247: 13244: 13241: 13240: 13238: 13234: 13227: 13224: 13220: 13216: 13213: 13210: 13207: 13206:Naples Plague 13204: 13201: 13198: 13195: 13192: 13189: 13186: 13183: 13180: 13177: 13174: 13171: 13168: 13165: 13164:London plague 13162: 13161: 13159: 13155: 13149: 13146: 13145:London plague 13143: 13140: 13137: 13134: 13133:London plague 13131: 13128: 13125: 13122: 13119: 13116: 13113: 13110: 13107: 13106: 13104: 13100: 13097: 13095: 13089: 13082: 13079: 13076: 13073: 13070: 13067: 13064: 13063:Plague of 664 13061: 13058: 13055: 13052: 13049: 13046: 13043: 13040: 13037: 13036: 13034: 13032: 13026: 13019: 13016: 13013: 13010: 13007: 13004: 12994: 12991: 12990: 12988: 12986: 12982: 12979: 12975: 12969: 12966: 12965: 12962: 12958: 12954: 12950: 12943: 12938: 12936: 12931: 12929: 12924: 12923: 12920: 12908: 12905: 12903: 12900: 12898: 12895: 12891: 12888: 12886: 12883: 12882: 12881: 12878: 12876: 12873: 12871: 12868: 12866: 12863: 12862: 12860: 12856: 12844: 12843: 12839: 12837: 12836: 12832: 12831: 12830: 12827: 12823: 12820: 12818: 12815: 12814: 12812: 12808: 12805: 12803: 12800: 12799: 12798: 12797:United States 12795: 12794: 12792: 12788: 12782: 12779: 12777: 12774: 12772: 12769: 12767: 12764: 12763: 12761: 12757: 12754: 12748: 12738: 12735: 12733: 12730: 12729: 12727: 12723: 12716: 12712: 12709: 12708: 12706: 12702: 12699: 12693: 12683: 12680: 12678: 12675: 12673: 12670: 12668: 12665: 12663: 12660: 12658: 12655: 12651: 12648: 12646: 12643: 12642: 12641: 12638: 12636: 12633: 12631: 12628: 12627: 12625: 12619: 12612: 12608: 12605: 12602: 12598: 12595: 12592: 12588: 12585: 12582: 12578: 12575: 12574: 12572: 12566: 12559: 12555: 12552: 12551: 12549: 12545: 12542: 12536: 12532: 12525: 12520: 12518: 12513: 12511: 12506: 12505: 12502: 12494: 12490: 12489:"Polio today" 12486: 12485: 12474: 12470: 12465: 12460: 12455: 12450: 12446: 12442: 12438: 12433: 12432: 12415: 12414: 12407: 12405: 12403: 12401: 12381: 12375: 12364: 12363: 12356: 12348: 12342: 12334: 12330: 12324: 12313: 12307: 12305: 12303: 12291: 12285: 12283: 12274: 12268: 12252: 12251:National Post 12248: 12242: 12227: 12223: 12216: 12200: 12196: 12192: 12185: 12169: 12165: 12159: 12157: 12140: 12136: 12132: 12125: 12109: 12105: 12099: 12091: 12087: 12083: 12079: 12075: 12069: 12054: 12049: 12041: 12033: 12027: 12019: 12012: 12006: 11990: 11984: 11968: 11962: 11946: 11939: 11923: 11916: 11900: 11893: 11885: 11879: 11871: 11867: 11862: 11857: 11853: 11849: 11845: 11841: 11837: 11830: 11828: 11811: 11804: 11802: 11785: 11779: 11771: 11765: 11754: 11748: 11732: 11725: 11717: 11711: 11695: 11691: 11685: 11683: 11681: 11679: 11677: 11675: 11673: 11671: 11669: 11667: 11665: 11648: 11644: 11638: 11636: 11619: 11615: 11611: 11604: 11588: 11584: 11580: 11574: 11566: 11562: 11556: 11540: 11536: 11529: 11513: 11509: 11508: 11503: 11496: 11488: 11484: 11479: 11474: 11470: 11466: 11462: 11458: 11454: 11447: 11445: 11436: 11432: 11428: 11424: 11419: 11414: 11409: 11404: 11400: 11396: 11392: 11385: 11369: 11365: 11364: 11359: 11352: 11336: 11332: 11326: 11310: 11306: 11302: 11295: 11279: 11275: 11271: 11264: 11248: 11244: 11240: 11234: 11218: 11214: 11210: 11204: 11188: 11184: 11177: 11161: 11157: 11153: 11146: 11130: 11126: 11122: 11115: 11099: 11095: 11094: 11089: 11082: 11063: 11059: 11052: 11046: 11030: 11026: 11025: 11020: 11013: 10997: 10993: 10991: 10986: 10980: 10964: 10960: 10959: 10954: 10950: 10944: 10942: 10925: 10921: 10917: 10913: 10909: 10905: 10901: 10894: 10875: 10872:(WHO). 2019. 10871: 10864: 10858: 10850: 10846: 10841: 10836: 10832: 10828: 10824: 10820: 10816: 10809: 10793: 10789: 10787: 10782: 10776: 10757: 10751: 10735: 10731: 10727: 10721: 10702: 10698: 10691: 10685: 10683: 10681: 10679: 10677: 10675: 10673: 10671: 10669: 10652: 10648: 10642: 10634: 10630: 10625: 10620: 10616: 10612: 10608: 10604: 10600: 10593: 10591: 10582: 10578: 10573: 10568: 10564: 10560: 10556: 10552: 10548: 10541: 10530: 10524: 10516: 10512: 10507: 10502: 10498: 10494: 10490: 10486: 10482: 10475: 10456: 10449: 10443: 10441: 10424: 10420: 10416: 10410: 10391: 10387: 10385: 10377: 10371: 10355: 10351: 10347: 10341: 10339: 10322: 10318: 10314: 10308: 10292: 10288: 10284: 10277: 10269: 10265: 10260: 10255: 10251: 10247: 10243: 10239: 10235: 10228: 10226: 10224: 10207: 10203: 10199: 10193: 10191: 10182: 10178: 10173: 10168: 10164: 10160: 10156: 10152: 10148: 10141: 10125: 10121: 10114: 10098: 10094: 10090: 10084: 10076: 10072: 10067: 10062: 10058: 10054: 10051:(21): 30542. 10050: 10046: 10042: 10038: 10031: 10023: 10019: 10014: 10009: 10005: 10001: 9997: 9993: 9989: 9982: 9980: 9963: 9959: 9955: 9951: 9947: 9940: 9932: 9928: 9923: 9918: 9914: 9910: 9906: 9902: 9898: 9891: 9872: 9868: 9864: 9859: 9854: 9850: 9846: 9842: 9838: 9831: 9824: 9808: 9804: 9800: 9794: 9775: 9771: 9764: 9758: 9742: 9738: 9736: 9731: 9725: 9709: 9705: 9701: 9694: 9675: 9671: 9664: 9658: 9642: 9638: 9634: 9628: 9612: 9608: 9604: 9597: 9581: 9577: 9575: 9570: 9564: 9557: 9544: 9540: 9534: 9515: 9511: 9504: 9498: 9479: 9475: 9468: 9462: 9446: 9442: 9438: 9432: 9416: 9412: 9408: 9402: 9400: 9380: 9376: 9369: 9363: 9344: 9340: 9333: 9327: 9311: 9307: 9303: 9296: 9280: 9276: 9272: 9265: 9249: 9245: 9244: 9239: 9233: 9217: 9213: 9212: 9207: 9203: 9197: 9181: 9177: 9176: 9171: 9164: 9148: 9144: 9140: 9134: 9118: 9114: 9113: 9108: 9104: 9098: 9082: 9078: 9077: 9072: 9066: 9050: 9046: 9042: 9035: 9020: 9019: 9011: 9005: 9003: 8986: 8982: 8975: 8960: 8956: 8952: 8948: 8944: 8940: 8939: 8934: 8927: 8911: 8910: 8905: 8899: 8892: 8881: 8877: 8872: 8867: 8863: 8859: 8855: 8851: 8850: 8845: 8838: 8823: 8819: 8815: 8811: 8807: 8806: 8801: 8794: 8779: 8775: 8770: 8765: 8761: 8757: 8753: 8752: 8747: 8740: 8721: 8717: 8715: 8707: 8701: 8699: 8697: 8695: 8693: 8691: 8671: 8667: 8660: 8654: 8638: 8634: 8630: 8623: 8607: 8603: 8601: 8596: 8590: 8574: 8570: 8569: 8564: 8558: 8539: 8535: 8531: 8527: 8523: 8516: 8509: 8493: 8489: 8488: 8483: 8476: 8460: 8456: 8449: 8447: 8427: 8423: 8419: 8413: 8394: 8390: 8388: 8380: 8374: 8372: 8370: 8368: 8366: 8364: 8362: 8345: 8341: 8337: 8331: 8323: 8319: 8314: 8309: 8304: 8299: 8295: 8291: 8290:PLOS Medicine 8287: 8280: 8264: 8260: 8258: 8253: 8247: 8231: 8227: 8223: 8217: 8201: 8197: 8191: 8175: 8171: 8165: 8157: 8153: 8149: 8145: 8141: 8137: 8130: 8128: 8111: 8107: 8103: 8097: 8081: 8077: 8073: 8067: 8048: 8041: 8035: 8016: 8012: 8008: 8004: 8000: 7993: 7986: 7970: 7966: 7962: 7956: 7940: 7936: 7929: 7927: 7925: 7923: 7914: 7910: 7906: 7902: 7898: 7894: 7887: 7871: 7867: 7863: 7860:(3): 99–108. 7859: 7855: 7847: 7840: 7821: 7817: 7811: 7804: 7803: 7795: 7793: 7776: 7772: 7766: 7764: 7762: 7760: 7758: 7756: 7754: 7752: 7750: 7748: 7746: 7744: 7724: 7720: 7713: 7707: 7705: 7703: 7701: 7699: 7697: 7695: 7693: 7691: 7689: 7672: 7668: 7664: 7658: 7656: 7654: 7652: 7650: 7648: 7646: 7644: 7642: 7633: 7629: 7624: 7619: 7615: 7611: 7604: 7597: 7581: 7577: 7573: 7566: 7564: 7547: 7543: 7539: 7533: 7531: 7514: 7510: 7508: 7503: 7497: 7495: 7493: 7473: 7466: 7460: 7444: 7440: 7433: 7417: 7413: 7409: 7403: 7387: 7383: 7379: 7375: 7371: 7364: 7356: 7352: 7347: 7342: 7337: 7332: 7328: 7324: 7320: 7316: 7312: 7305: 7289: 7285: 7283: 7278: 7272: 7265: 7250: 7246: 7244: 7236: 7229: 7221: 7217: 7212: 7207: 7202: 7197: 7193: 7189: 7185: 7178: 7176: 7167: 7163: 7158: 7153: 7148: 7143: 7139: 7135: 7131: 7124: 7122: 7105: 7101: 7099: 7094: 7088: 7086: 7084: 7067: 7063: 7059: 7053: 7051: 7034: 7030: 7028: 7023: 7017: 7015: 6998: 6994: 6993: 6988: 6981: 6965: 6961: 6960: 6955: 6949: 6933: 6929: 6925: 6919: 6903: 6899: 6898: 6893: 6886: 6870: 6864: 6848: 6844: 6843: 6838: 6831: 6815: 6811: 6810: 6805: 6798: 6782: 6778: 6774: 6767: 6751: 6747: 6743: 6737: 6721: 6717: 6716: 6711: 6704: 6696: 6692: 6687: 6682: 6678: 6674: 6670: 6663: 6647: 6643: 6642: 6637: 6630: 6622: 6618: 6613: 6608: 6604: 6600: 6596: 6592: 6588: 6581: 6579: 6577: 6575: 6573: 6564: 6560: 6555: 6550: 6546: 6542: 6538: 6534: 6530: 6523: 6521: 6512: 6508: 6503: 6498: 6494: 6490: 6486: 6482: 6478: 6471: 6463: 6459: 6454: 6449: 6445: 6441: 6437: 6433: 6429: 6422: 6414: 6410: 6405: 6400: 6396: 6392: 6388: 6384: 6380: 6373: 6371: 6369: 6352: 6348: 6344: 6337: 6335: 6333: 6313: 6309: 6305: 6300: 6295: 6291: 6287: 6280: 6273: 6265: 6261: 6256: 6251: 6247: 6243: 6239: 6232: 6224: 6220: 6215: 6210: 6205: 6200: 6196: 6192: 6188: 6181: 6165: 6161: 6159: 6154: 6148: 6132: 6128: 6124: 6118: 6102: 6098: 6092: 6076: 6072: 6065: 6063: 6061: 6059: 6057: 6055: 6053: 6051: 6031: 6027: 6023: 6018: 6013: 6009: 6005: 6001: 5997: 5990: 5983: 5981: 5979: 5977: 5968: 5964: 5959: 5954: 5949: 5944: 5940: 5936: 5932: 5925: 5909: 5905: 5901: 5895: 5887: 5883: 5878: 5873: 5869: 5865: 5861: 5857: 5853: 5846: 5831: 5827: 5820: 5812: 5808: 5803: 5798: 5794: 5790: 5785: 5780: 5776: 5772: 5768: 5761: 5753: 5749: 5744: 5739: 5735: 5731: 5727: 5723: 5719: 5712: 5693: 5689: 5685: 5681: 5677: 5673: 5669: 5662: 5655: 5639: 5635: 5628: 5612: 5608: 5604: 5598: 5590: 5586: 5581: 5576: 5572: 5568: 5564: 5560: 5556: 5549: 5530: 5526: 5522: 5517: 5512: 5508: 5504: 5500: 5496: 5489: 5482: 5463: 5459: 5455: 5450: 5445: 5441: 5437: 5430: 5423: 5407: 5403: 5399: 5393: 5391: 5375: 5371: 5364: 5348: 5344: 5338: 5330: 5326: 5322: 5318: 5314: 5310: 5303: 5301: 5292: 5288: 5283: 5278: 5273: 5268: 5264: 5260: 5256: 5249: 5234: 5230: 5224: 5222: 5220: 5218: 5216: 5214: 5212: 5192: 5188: 5184: 5180: 5173: 5166: 5150: 5146: 5142: 5136: 5117: 5113: 5107: 5103: 5099: 5095: 5088: 5087: 5079: 5060: 5056: 5052: 5048: 5044: 5037: 5030: 5011: 5007: 5003: 4999: 4995: 4988: 4982: 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4254: 4252: 4249: 4248: 4242: 4237: 4234: 4231: 4229: 4226: 4225: 4219: 4214: 4211: 4208: 4206: 4203: 4202: 4196: 4191: 4188: 4185: 4183: 4180: 4179: 4173: 4168: 4165: 4162: 4160: 4157: 4156: 4146: 4141: 4136: 4133: 4131: 4128: 4127: 4121: 4116: 4113: 4110: 4108: 4105: 4104: 4098: 4093: 4090: 4087: 4085: 4082: 4081: 4075: 4070: 4067: 4064: 4062: 4059: 4058: 4052: 4047: 4044: 4041: 4039: 4036: 4035: 4031: 4026: 4017: 4012: 4009: 4008: 4001: 3997: 3992: 3982: 3980: 3975: 3970: 3964: 3962: 3957: 3948: 3946: 3943: 3940: 3938: 3935: 3934: 3928: 3923: 3920: 3917: 3915: 3912: 3911: 3905: 3900: 3897: 3894: 3892: 3889: 3888: 3882: 3877: 3874: 3871: 3869: 3866: 3865: 3859: 3854: 3851: 3848: 3846: 3843: 3842: 3836: 3831: 3828: 3825: 3823: 3820: 3819: 3813: 3808: 3805: 3802: 3800: 3797: 3796: 3790: 3785: 3782: 3779: 3777: 3774: 3773: 3767: 3762: 3759: 3756: 3754: 3751: 3750: 3744: 3739: 3736: 3733: 3731: 3728: 3727: 3721: 3716: 3713: 3710: 3708: 3705: 3704: 3694: 3689: 3684: 3681: 3679: 3676: 3675: 3669: 3664: 3661: 3658: 3656: 3653: 3652: 3646: 3641: 3638: 3635: 3633: 3630: 3629: 3623: 3618: 3615: 3612: 3610: 3607: 3606: 3600: 3595: 3592: 3589: 3587: 3584: 3583: 3577: 3572: 3569: 3566: 3564: 3561: 3560: 3554: 3549: 3546: 3543: 3541: 3538: 3537: 3531: 3526: 3523: 3520: 3518: 3515: 3514: 3508: 3503: 3500: 3497: 3495: 3492: 3491: 3485: 3480: 3477: 3474: 3472: 3469: 3468: 3462: 3457: 3454: 3451: 3449: 3446: 3445: 3439: 3434: 3431: 3428: 3426: 3423: 3422: 3412: 3407: 3402: 3399: 3397: 3394: 3393: 3387: 3382: 3379: 3376: 3374: 3371: 3370: 3364: 3359: 3356: 3353: 3351: 3348: 3347: 3343: 3338: 3329: 3324: 3321: 3320: 3313: 3309: 3304: 3294: 3292: 3286: 3284: 3278: 3268: 3266: 3263: 3260: 3258: 3255: 3254: 3248: 3243: 3240: 3237: 3235: 3234:United States 3232: 3231: 3225: 3220: 3217: 3214: 3212: 3209: 3208: 3202: 3197: 3194: 3191: 3189: 3186: 3185: 3179: 3174: 3171: 3168: 3166: 3163: 3162: 3156: 3151: 3148: 3145: 3143: 3140: 3139: 3133: 3128: 3125: 3122: 3120: 3117: 3116: 3110: 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1966: 1957: 1952: 1949: 1948: 1941: 1937: 1932: 1922: 1918: 1914: 1912: 1907: 1900: 1896: 1892: 1888: 1884: 1882: 1878: 1874: 1864: 1860: 1856: 1853: 1851: 1847: 1843: 1837: 1833: 1831: 1825: 1823: 1822:intramuscular 1819: 1809: 1800: 1796: 1792: 1785: 1781: 1779: 1775: 1771: 1767: 1763: 1759: 1755: 1751: 1747: 1743: 1739: 1733: 1725: 1723: 1718: 1717:of Ethiopia. 1716: 1715:Somali Region 1712: 1707: 1705: 1701: 1697: 1693: 1682: 1680: 1676: 1672: 1668: 1664: 1654: 1646: 1637: 1631: 1627: 1623: 1619: 1613: 1611: 1607: 1603: 1599: 1595: 1591: 1587: 1583: 1579: 1575: 1571: 1567: 1563: 1559: 1555: 1554:Côte d'Ivoire 1551: 1547: 1541: 1537: 1535: 1531: 1527: 1522: 1520: 1516: 1512: 1506: 1504: 1500: 1496: 1492: 1482: 1480: 1476: 1466: 1464: 1460: 1456: 1452: 1448: 1444: 1442: 1438: 1434: 1430: 1426: 1421: 1419: 1386: 1382: 1380: 1379:Côte d'Ivoire 1376: 1368: 1363: 1361: 1357: 1356:Uttar Pradesh 1351: 1349: 1346: 1292: 1259: <0.3 1253: no data 1248: 1247: 1242: 1238: 1229: 1227: 1223: 1219: 1215: 1212:, India, and 1211: 1207: 1202: 1195: 1193: 1189: 1185: 1181: 1177: 1176:Mediterranean 1173: 1169: 1165: 1161: 1160:Mediterranean 1157: 1152: 1150: 1145: 1142: 1140: 1136: 1128: 1124: 1120: 1116: 1112: 1108: 1105:In 1988, the 1098: 1096: 1092: 1088: 1083: 1081: 1077: 1073: 1068: 1064: 1060: 1052: 1047: 1033: 1030: 1027: 1026: 1022: 1019: 1016: 1015: 1011: 1008: 1005: 1004: 1000: 997: 995: 992: 991: 987: 984: 981: 980: 976: 973: 970: 969: 965: 962: 959: 958: 954: 951: 948: 947: 943: 940: 938: 935: 934: 930: 927: 924: 923: 919: 916: 913: 912: 908: 905: 902: 901: 897: 894: 891: 890: 886: 883: 881: 878: 877: 872: 868: 865: 863: 860: 859: 854: 850: 847: 845: 842: 841: 836: 832: 829: 827: 824: 823: 818: 814: 811: 808: 807: 802: 798: 795: 793: 790: 789: 784: 780: 777: 774: 773: 768: 764: 761: 759: 756: 755: 750: 746: 743: 741: 738: 737: 732: 728: 725: 723: 720: 719: 715: 712: 709: 708: 705: 701: 693: 676: 672: 670: 666: 662: 658: 654: 650: 645: 643: 639: 635: 634: 628: 625: 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13008:(429–426 BC) 12955:and notable 12880:Transmission 12840: 12833: 12650:epidemiology 12590: 12492: 12444: 12440: 12412: 12387:. 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Peshawar. 6641:The Guardian 6639: 6629: 6594: 6590: 6536: 6532: 6484: 6480: 6470: 6435: 6431: 6421: 6386: 6382: 6355:. Retrieved 6346: 6319:. Retrieved 6289: 6285: 6272: 6245: 6241: 6231: 6194: 6190: 6180: 6170:13 September 6168:. Retrieved 6164:the original 6156: 6147: 6135:. Retrieved 6131:the original 6117: 6105:. Retrieved 6101:the original 6091: 6079:. Retrieved 6075:the original 6037:. Retrieved 5999: 5995: 5938: 5934: 5924: 5912:. Retrieved 5894: 5859: 5855: 5845: 5833:. Retrieved 5829: 5819: 5774: 5770: 5760: 5725: 5721: 5711: 5699:. Retrieved 5671: 5667: 5654: 5642:. Retrieved 5627: 5615:. Retrieved 5611:the original 5597: 5562: 5558: 5548: 5536:. Retrieved 5498: 5494: 5481: 5469:. Retrieved 5439: 5435: 5422: 5410:. Retrieved 5377:. Retrieved 5373: 5363: 5351:. Retrieved 5346: 5337: 5312: 5308: 5262: 5258: 5248: 5236:. Retrieved 5232: 5198:. Retrieved 5187:10665/276245 5165: 5153:. Retrieved 5144: 5135: 5123:. Retrieved 5085: 5078: 5066:. Retrieved 5046: 5042: 5029: 5017:. 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Retrieved 4636:the original 4631: 4622: 4579: 4540: 4536: 4532: 4529: 4521: 4518: 4503: 4499: 4480: 4027:Transmission 3995: 3965: 3958: 3955: 3936: 3753:Burkina Faso 3339:Transmission 3307: 3287: 3279: 3275: 3256: 2627:Transmission 2595: 2579: 2571: 2563: 2560: 2541: 2404:Burkina Faso 2289:Sierra Leone 2016:reintroduced 1967:Transmission 1935: 1919: 1915: 1908: 1905: 1893: 1889: 1885: 1869: 1857: 1854: 1838: 1834: 1826: 1814: 1797: 1793: 1790: 1734: 1726: 1719: 1708: 1694:(focused in 1683: 1677:prefecture, 1659: 1626:Turkmenistan 1614: 1586:Sierra Leone 1566:Burkina Faso 1542: 1538: 1523: 1519:Birnin Kebbi 1507: 1488: 1467: 1445: 1422: 1415: 1364: 1352: 1338:By 2001, 575 1337: 1327: >10 1321: 7.5–10 1297: 2.55–3 1203: 1196: 1153: 1146: 1143: 1104: 1094: 1084: 1056: 1051:East Germany 993: 936: 879: 861: 843: 825: 791: 757: 739: 721: 703: 682: 673: 669:John Brennan 665:Leon Panetta 646: 631: 629: 621: 598: 594: 577: 574: 566: 525: 517: 508: 504: 500: 497:Surveillance 469: 426: 413:transmission 402: 385: 365: 347: 318: 293:adenoviruses 275:and reduced 254:immunization 250:transmission 244: 216: 208:transmission 187: 167: 145: 137:asymptomatic 110: 57: 56: 36: 13993:Vaccination 13953:(2023–2024) 13947:(2022–2023) 13931:(2009–2010) 13919:(1977–1979) 13913:(1968–1970) 13907:(1961–1975) 13901:(1957–1958) 13895:(1919–1930) 13889:(1918–1920) 13887:Spanish flu 13883:(1899–1923) 13877:(1889–1890) 13875:Russian flu 13871:(1881–1896) 13865:(1863–1879) 13859:(1855–1860) 13853:(1852–1860) 13847:(1829–1851) 13841:(1816–1826) 13835:(1557–1559) 13765:(2022–2023) 13753:(2019–2020) 13747:(2019–2020) 13745:DRC measles 13699:(2018–2020) 13667:(2016–2022) 13655:(2015–2016) 13611:(2013–2016) 13605:(2013–2014) 13603:Chikungunya 13569:(2010–2019) 13563:(2009–2010) 13545:(2008–2017) 13539:(2008–2009) 13503:(2003–2005) 13491:(2002–2004) 13473:(1998–1999) 13454:(1972–1973) 13418:(1910–1911) 13412:(1900–1904) 13377:(1862–1863) 13347:(1847–1848) 13341:(1837–1838) 13323:(1813–1814) 13317:(1812–1819) 13287:(1793–1798) 13281:(1780–1782) 13269:(1770–1772) 13257:(1720–1722) 13251:(1710–1712) 13245:(1707–1708) 13221:(1675–1676) 13214:(1665–1666) 13196:(1647–1652) 13190:(1633–1644) 13178:(1629–1631) 13147:(1592–1593) 13141:(1592–1593) 13135:(1563–1564) 13129:(1557–1559) 13083:(1485–1551) 13077:(1346–1353) 13075:Black Death 13000: 1330 12902:Vaccination 12822:Pulse Polio 12750:Eradication 11816:18 February 11790:18 February 11193:21 November 11035:20 February 10710:29 November 10657:22 November 10464:22 November 9704:Daily Trust 9285:12 November 8816:: 190–194. 8762:: 270–274. 7829:8 September 7441:. Reuters. 6487:(9): E302. 6107:19 February 5265:(8): 1329. 5102:10665/42850 4866:www.who.int 4642:11 February 4514:Middle East 4205:South Sudan 4038:Afghanistan 4018:Circulating 3776:South Sudan 3609:Ivory Coast 3350:Afghanistan 3330:Circulating 2699:Afghanistan 2618:Circulating 2243:South Sudan 1978:Afghanistan 1958:Circulating 1778:Timor-Leste 1746:North Korea 1630:Brazzaville 1495:Afghanistan 1437:Pulse Polio 1315: 5–7.5 1228:in Africa. 1149:Pulse Polio 661:his killing 653:hepatitis B 620:in issuing 613:colonialism 562:South Sudan 422:vaccination 307:Vaccination 289:echoviruses 277:muscle tone 228:specificity 224:sensitivity 170:Afghanistan 125:inactivated 113:vaccination 76:(WHO), the 13967:Categories 13697:Kivu Ebola 13452:London flu 12885:horizontal 12711:Rinderpest 12704:Successful 12623:(regional) 12547:Successful 11947:. Politico 11928:28 January 11737:19 October 11241:(Report). 11223:2 November 11158:(CIDRAP). 10868:(Report). 10798:27 October 10429:24 January 10360:21 October 9968:19 January 9880:27 October 9747:9 February 9668:(Report). 9647:28 October 9508:(Report). 9472:(Report). 9373:(Report). 9337:(Report). 9254:27 October 9087:27 October 8679:3 February 8612:24 January 8547:27 October 8498:7 February 8465:19 January 8435:21 October 8350:7 February 8296:(3): e73. 8236:2 February 8086:2 February 8024:27 October 7945:2 February 7677:10 January 7586:2 February 7552:24 October 7481:10 October 7449:10 October 7412:IFLScience 7258:10 October 7140:(1): 521. 7039:10 October 6321:27 October 6137:28 October 6081:2 February 6039:27 October 5777:(3): 183. 5471:27 October 5177:(Report). 5155:28 October 5125:26 October 5092:. Geneva: 5068:27 October 5019:27 October 4768:2 November 4703:14 October 4672:9 November 4614:References 4469:cVDPV only 4446:cVDPV only 4435:Mozambique 4423:cVDPV only 4400:cVDPV only 4377:cVDPV only 4354:cVDPV only 4331:cVDPV only 4308:cVDPV only 4285:cVDPV only 4262:cVDPV only 4239:cVDPV only 4216:cVDPV only 4193:cVDPV only 4170:cVDPV only 4143:cVDPV only 4118:cVDPV only 4095:cVDPV only 3925:cVDPV only 3902:cVDPV only 3879:cVDPV only 3856:cVDPV only 3845:Mauritania 3833:cVDPV only 3810:cVDPV only 3787:cVDPV only 3764:cVDPV only 3741:cVDPV only 3718:cVDPV only 3691:cVDPV only 3678:Mozambique 3666:cVDPV only 3643:cVDPV only 3620:cVDPV only 3597:cVDPV only 3574:cVDPV only 3551:cVDPV only 3528:cVDPV only 3505:cVDPV only 3494:Madagascar 3482:cVDPV only 3459:cVDPV only 3436:cVDPV only 3409:cVDPV only 3245:cVDPV only 3222:cVDPV only 3199:cVDPV only 3188:Rep. Congo 3176:cVDPV only 3153:cVDPV only 3130:cVDPV only 3107:cVDPV only 3084:cVDPV only 3061:cVDPV only 3038:cVDPV only 3015:cVDPV only 2992:cVDPV only 2969:cVDPV only 2946:cVDPV only 2923:cVDPV only 2900:cVDPV only 2877:cVDPV only 2854:cVDPV only 2831:cVDPV only 2820:Madagascar 2808:cVDPV only 2785:cVDPV only 2762:cVDPV only 2735:cVDPV only 2661:Mozambique 2530:cVDPV only 2507:cVDPV only 2484:cVDPV only 2461:cVDPV only 2450:Rep. Congo 2438:cVDPV only 2427:Mozambique 2415:cVDPV only 2392:cVDPV only 2369:cVDPV only 2346:cVDPV only 2323:cVDPV only 2300:cVDPV only 2277:cVDPV only 2254:cVDPV only 2231:cVDPV only 2208:cVDPV only 2197:Madagascar 2185:cVDPV only 2162:cVDPV only 2139:cVDPV only 2116:cVDPV only 2105:Tajikistan 2089:cVDPV only 2066:cVDPV only 1830:Boko Haram 1824:delivery. 1738:Bangladesh 1622:Kazakhstan 1618:Tajikistan 1578:Mauritania 1499:Bangladesh 1345:Copenhagen 1210:Bangladesh 1041:1950s–1987 589:See also: 550:cold chain 409:poliovirus 329:attenuated 232:vertebrate 201:poliovirus 197:extinction 165:1 (WPV1). 106:rinderpest 88:(CDC) and 62:poliovirus 52:Poliovirus 13929:Swine flu 13899:Asian flu 13817:(541–767) 13786:Argentina 13071:(735–737) 13065:(664–689) 13059:(638–639) 13053:(627–628) 13041:(541–542) 13031:classical 13020:(250–266) 12953:epidemics 12949:Pandemics 12389:9 January 12231:21 August 11812:. 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