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and can cause bowel ischemia sometimes leading to bowel infarction. Diverticulitis (26.5%) and acute appendicitis (22%) are the two most common causes. Pylephlebitis is caused by a single pathogen in 43% of cases and polymicrobial in 27% of cases. The most frequently isolated bacteria are
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In the modern era, it is usually diagnosed by CT scans of the abdomen and pelvis. Bacteriology is often polymicrobial and blood cultures are positive in some cases. A significant fraction of people presenting with this condition have an underlying
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Fusaro, Lisa; Di Bella, Stefano; Martingano, Paola; Crocè, Lory
Saveria; Giuffrè, Mauro (2023). "Pylephlebitis: A Systematic Review on Etiology, Diagnosis, and Treatment of Infective Portal Vein Thrombosis".
225:, and right upper quadrant abdominal pain, but sometimes abdominal pain may be absent. Liver function test abnormalities are usually present but frank jaundice is uncommon.
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Singh, P.; Yadav, N.; Visvalingam, V.; Indaram, A.; Bank, S. (2001). "Pylephlebitis--diagnosis and management".
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197:) that is caused by infection. It is usually a complication of intra-abdominal sepsis, most often following
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if other clots are present outside the portal vein or if fever persists on antibiotic therapy.
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339:. 13 (3): 429. doi:10.3390/diagnostics13030429. ISSN 2075-4418. PMC 9914785. PMID 36766534.
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Treatment is with a prolonged course of broad-spectrum antibiotics, with the addition of
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Kumar, V.; Abbas, A. K.; Fausto, N.; Robbins, S. L.; Cotran, R. S. (2015).
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if you can. Unsourced or poorly sourced material may be challenged and
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Inflammation of the portal vein or any of its branches due to infection
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Infective suppurative thrombosis of the portal vein
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329:Robbins and Cotran Pathologic Basis of Disease
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213:era, it still carries a mortality of 10-30%.
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209:. Considered uniformly lethal in the pre-
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221:It typically presents with fever,
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