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Stepwise reaction

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228: 66:. A stepwise reaction distinguishes itself from an elementary reaction in which the transformation is assumed to occur in a single step and to pass through a single 81:
of stepwise reactions is obtained by combining the rate laws of the multiple elementary steps, and can become rather complex. Moreover, when speaking about
269: 293: 85:, the diffusion may also limit the reaction. In general, however, there is one very slow step, which is the 58:
are broken and formed at the same time. Hence, intermediates appear in the reaction pathway going from the
262: 288: 172: 135:. This proves the stepwise nature of the reaction and the structure of the intermediate. For example, 255: 167: 86: 44: 243: 8: 182: 157: 63: 48: 89:, i.e. the reaction doesn't proceed any faster than the rate-determining step proceeds. 82: 74: 235: 177: 152: 92: 40: 67: 95:, especially when involving catalysis, are often stepwise. For example, a typical 239: 282: 162: 55: 227: 140: 211: 200: 16:
Chemical reaction involving two or more consecutive elementary reactions
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R is an electron acceptor, for example, the carbon of a
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reaction consists of at least these elementary steps:
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In contrast to elementary reactions which follow the
280: 263: 131:Reaction intermediates may be trapped in a 270: 256: 281: 124:(C=O). A very strong base, usually an 222: 139:were used to prove the existence of 13: 14: 305: 188: 103:Deprotonation next to (α to) the 226: 128:, is needed for the first step. 54:In a stepwise reaction, not all 205: 194: 1: 242:. You can help Knowledge by 7: 146: 10: 310: 221: 212:IUPAC Gold Book definition 201:IUPAC Gold Book definition 173:Steady state approximation 294:Chemical reaction stubs 45:reaction intermediates 168:Rate-determining step 115:R + C=C−O → R−C−C=O 87:rate-determining step 39:, among others) is a 49:elementary reactions 183:Lindemann mechanism 158:Elementary reaction 113:Attack of enolate: 83:catalytic reactions 75:law of mass action 37:multistep reaction 289:Chemical kinetics 251: 250: 236:chemical reaction 178:Chemical kinetics 153:Chemical reaction 133:trapping reaction 93:Organic reactions 43:with one or more 41:chemical reaction 25:stepwise reaction 301: 272: 265: 258: 230: 223: 214: 209: 203: 198: 116: 110: 68:transition state 33:complex reaction 29:overall reaction 27:(also called an 309: 308: 304: 303: 302: 300: 299: 298: 279: 278: 277: 276: 219: 217: 210: 206: 199: 195: 191: 149: 114: 108: 17: 12: 11: 5: 307: 297: 296: 291: 275: 274: 267: 260: 252: 249: 248: 231: 216: 215: 204: 192: 190: 189:External links 187: 186: 185: 180: 175: 170: 165: 160: 155: 148: 145: 118: 117: 111: 109:HC−C=O → C=C−O 15: 9: 6: 4: 3: 2: 306: 295: 292: 290: 287: 286: 284: 273: 268: 266: 261: 259: 254: 253: 247: 245: 241: 238:article is a 237: 232: 229: 225: 224: 220: 213: 208: 202: 197: 193: 184: 181: 179: 176: 174: 171: 169: 166: 164: 163:Rate equation 161: 159: 156: 154: 151: 150: 144: 142: 138: 134: 129: 127: 123: 112: 106: 102: 101: 100: 98: 94: 90: 88: 84: 80: 76: 71: 69: 65: 61: 57: 52: 50: 46: 42: 38: 34: 30: 26: 22: 244:expanding it 233: 218: 207: 196: 141:carbocations 132: 130: 119: 91: 72: 53: 36: 32: 28: 24: 18: 283:Categories 137:superacids 60:reactants 21:chemistry 147:See also 126:alkoxide 122:carbonyl 105:carbonyl 79:rate law 64:products 62:to the 77:, the 35:, and 234:This 56:bonds 240:stub 97:enol 23:, a 19:In 285:: 143:. 107:: 70:. 51:. 31:, 271:e 264:t 257:v 246:.

Index

chemistry
chemical reaction
reaction intermediates
elementary reactions
bonds
reactants
products
transition state
law of mass action
rate law
catalytic reactions
rate-determining step
Organic reactions
enol
carbonyl
carbonyl
alkoxide
superacids
carbocations
Chemical reaction
Elementary reaction
Rate equation
Rate-determining step
Steady state approximation
Chemical kinetics
Lindemann mechanism
IUPAC Gold Book definition
IUPAC Gold Book definition
Stub icon
chemical reaction

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