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Subdural hematoma

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579: 479: 587: 40: 968:(CSDHs) have a relatively high mortality rate (up to 16.7% in patients over the age of 65); however, they have an even higher rate of recurrence (as mentioned in the previous section). For the aforementioned reasons, researchers have developed predictive grading scales to identify patients at high risk of CSDH recurrence, one of which is the Puerto Rico Recurrence Scale developed by Mignucci-Jiménez et al. 738:
stops by itself. Because these hematomas progress slowly, they can more often be stopped before they cause significant damage, especially if they are less than a centimeter wide. In one study, only 22% of patients with chronic subdural bleeds had outcomes worse than "good" or "complete recovery". Chronic subdural hematomas are common in the elderly.
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indicator of subdural hemorrhage is its involvement of a larger portion of the cerebral hemisphere. Subdural blood can also be seen as a layering density along the tentorium cerebelli. This can be a chronic, stable process, since the feeding system is low-pressure. In such cases, subtle signs of bleeding—such as effacement of
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can reduce the haematoma volume and improving neurological function in eight weeks. HMG-CoA reductase inhibitor may also reduce risk of recurrences in CSDH. Dexamethasone, when used together with surgical drainage, may reduce the recurrence rate of subdural haematoma. Even with surgical evacuation of
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and ruptured cortical vessels (blood vessels on the surface of the brain) can also cause subdural hematoma. In these cases, blood usually accumulates between the two layers of the dura mater. This can cause ischemic brain damage by two mechanisms: one, pressure on the cortical blood vessels, and two,
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Chronic subdural bleeds develop over a period of days to weeks, often after minor head trauma, though a cause is not identifiable in 50% of patients. They may not be discovered until they present clinically months or years after a head injury. The bleeding from a chronic hematoma is slow and usually
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On a CT scan, subdural hematomas are classically crescent-shaped, with a concave surface away from the skull. However, they can have a convex appearance, especially in the early stages of bleeding. This may cause difficulty in distinguishing between subdural and epidural hemorrhages. A more reliable
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score, younger age and responsive pupils are associated with better outcomes in acute subdural hematomas, while the time between the injury and the surgical evacuation, or the type of surgery, do not have a statistically significant impact on the outcomes. Additionally, chronic subdural hematomas
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that traverse the space must cover a wider distance, making them more vulnerable to tears. The elderly also have more brittle veins, making chronic subdural bleeds more common. Infants, too, have larger subdural spaces and are more predisposed to subdural bleeds than are young adults. It is often
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Those with chronic subudural haematoma (CSDH) with few or no symptoms or have high risk of complication during surgery may be treated conservatively with medications such as atorvastatin, dexamethasone, and mannitol, although supporting conservative treatment is still weak.
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is another risk factor for the development of chronic subdural hematoma. The incision in the arachnoid membrane during the operation causes cerebrospinal fluid to leak into the subdural space, leading to inflammation. This complication usually resolves on its own.
726:. Though much faster than chronic subdural bleeds, acute subdural bleeding is usually venous and therefore slower than the arterial bleeding of an epidural hemorrhage. Acute subdural hematomas due to trauma are the most lethal of all head injuries and have a high 427:
Acute subdural hematoma is usually caused by external trauma that creates tension in the wall of a bridging vein as it passes between the arachnoid and dural layers of the brain's lining—i.e., the subdural space. The circumferential arrangement of
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Acute subdural hematomas have one of the highest mortality rates of all head injuries, with 50 to 90 percent of cases resulting in death, depending on the underlying brain injury. About 20 to 30 percent of patients recover brain function. Higher
703:, but becomes more hypodense over time due to dissolution of cellular elements. After 3–14 days, the bleeding becomes isodense with brain tissue and may therefore be missed. Subsequently, it will become more hypodense than brain tissue. 470:, raising the dural venous pressure and resulting in more bleeding from the ruptured bridging veins. They stop growing only when the pressure of the hematoma equalizes with the intracranial pressure, as the space for expansion shrinks. 921:. A surgeon opens the skull and then the dura mater; removes the clot with suction or irrigation; and identifies and controls sites of bleeding. The injured vessels must be repaired. Postoperative complications can include increased 2040:
Santarius T, Kirkpatrick PJ, Ganesan D, Chia HL, Jalloh I, Smielewski P, et al. (September 2009). "Use of drains versus no drains after burr-hole evacuation of chronic subdural haematoma: a randomised controlled trial".
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Yamamoto H, Hirashima Y, Hamada H, Hayashi N, Origasa H, Endo S (June 2003). "Independent predictors of recurrence of chronic subdural hematoma: results of multivariate analysis performed using a logistic regression model".
354:. Cerebral atrophy increases the length the bridging veins have to traverse between the two meningeal layers, thus increasing the likelihood of shearing forces causing a tear. It is also more common in patients on 1969: 2549: 2526: 1426:
Mori K, Yamamoto T, Horinaka N, Maeda M (September 2002). "Arachnoid cyst is a risk factor for chronic subdural hematoma in juveniles: twelve cases of chronic subdural hematoma associated with arachnoid cyst".
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of acute hematomas may appear in minutes, if not immediately, but can also be delayed as much as two weeks. Symptoms of chronic subdural hematomas are usually delayed more than three weeks after injury.
2322:"Steroid for chronic subdural hematoma? A prospective phase IIB pilot randomized controlled trial on the use of dexamethasone with surgical drainage for the reduction of recurrence with reoperation" 3767: 158:, which in turn can cause compression of and damage to delicate brain tissue. Acute subdural hematomas are often life-threatening. Chronic subdural hematomas have a better 1980: 2450:
Mignucci-Jiménez, Giancarlo; Matos-Cruz, Alejandro J.; Abramov, Irakliy; Hanalioglu, Sahin; Kovacs, Melissa S.; Preul, Mark C.; Feliciano-Valls, Caleb E. (3 June 2022).
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The symptoms of a subdural hematoma have a slower onset than those of epidural hematomas because the lower-pressure veins involved bleed more slowly than arteries.
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pressure, which can reduce pressure in the subarachnoid space, pulling the arachnoid away from the dura mater and leading to a rupture of the blood vessels.
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Treatment of a subdural hematoma depends on its size and rate of growth. Some small subdural hematomas can be managed by careful monitoring as the
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claimed that subdural hematoma is a common finding in shaken baby syndrome, although there is no science to support this. In juveniles, an
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In chronic subdural hematomas, blood accumulates in the dural space as a result of damage to the dural border cells. The resulting
1921:"Correlation between the skull base fracture and the incidence of intracranial hemorrhage in patients with traumatic brain injury" 751: 3904: 3399: 2716: 1773:
Schweitzer AD, Niogi SN, Whitlow CT, Tsiouris AJ (October 2019). "Traumatic Brain Injury: Imaging Patterns and Complications".
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if they are not rapidly treated with surgical decompression. The mortality rate is higher than that of epidural hematomas and
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also causes leakage of cerebrospinal fluid into the hematoma cavity, increasing the size of the hematoma over time. Excessive
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Acute bleeds often develop after high-speed acceleration or deceleration injuries. They are most severe if associated with
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Graham DI, Gennareli TA (2000). "Chapter 5: Pathology of brain damage after head injury". In Cooper P, Golfinos G (eds.).
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Soleman J, Nocera F, Mariani L (2017). "The conservative and pharmacological management of chronic subdural haematoma".
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Miller JD, Nader R (June 2014). "Acute subdural hematoma from bridging vein rupture: a potential mechanism for growth".
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or brain damage will be present. Other symptoms of subdural hematoma can include any combination of the following:
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Thotakura AK, Marabathina NR (December 2015). "Nonsurgical Treatment of Chronic Subdural Hematoma with Steroids".
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Koivisto T, Jääskeläinen JE (September 2009). "Chronic subdural haematoma – to drain or not to drain?".
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because the force required to cause subdural hematomas tends to cause other severe injuries as well.
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of a chronic subdural hematoma, as demonstrated by thin strands of collagen and neovascularization.
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Subdural hematomas grow continually larger as a result of the pressure they place on the brain: As
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due to various rotational or linear forces. There are claims that they can occur in cases of
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Pro-inflammatory mediators active in the hematoma expansion process include Interleukin 1α (
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Beck J, Gralla J, Fung C, Ulrich CT, Schucht P, Fichtner J, et al. (December 2014).
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by restricting blood flow to the brain. When the brain is denied adequate blood flow, a
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Koç, R. Kemal; Akdemir, Hidayet; Oktem, I. Suat; Meral, Mehmet; Menkü, Ahmet (1997).
2343: 2302: 2251: 2188: 2150: 2115: 2086:"Anticonvulsants for preventing seizures in patients with chronic subdural haematoma" 2058: 2014: 1950: 1901: 1802: 1790: 1702: 1688: 1634: 1600: 1536: 1482: 1444: 1385: 1349: 1300: 1232: 1160: 1148: 1050: 934: 359: 185:. SAH are often seen in trauma settings, or after rupture of intracranial aneurysms. 166: 55: 2620: 2426: 2026: 1494: 3979: 3969: 3932: 3837: 3707: 3599: 3492: 3188: 2471: 2463: 2406: 2355: 2333: 2292: 2282: 2241: 2233: 2180: 2142: 2105: 2101: 2097: 2070: 2050: 2006: 1940: 1932: 1891: 1782: 1692: 1684: 1590: 1580: 1474: 1436: 1377: 1339: 1312: 1290: 1222: 1212: 1138: 1040: 1032: 836: 712: 666: 637: 552: 509: 478: 452: 440: 351: 1021:"Clinical analysis of risk factors related to recurrent chronic subdural hematoma" 382:
Factors increasing the risk of a subdural hematoma include very young or very old
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Faried A, Halim D, Widjaya IA, Badri RF, Sulaiman SF, Arifin MZ (October 2019).
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Edlmann E, Giorgi-Coll S, Whitfield PC, Carpenter KL, Hutchinson PJ (May 2017).
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chronic subdural haematoma, the recurrence rate is high, ranging from 7 to 20%.
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If the bleeds are large enough to put pressure on the brain, signs of increased
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It is important that a person receive medical assessment, including a complete
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Jiang R, Zhao S, Wang R, Feng H, Zhang J, Li X, et al. (November 2018).
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Lynøe N, Elinder G, Hallberg B, Rosén M, Sundgren P, Eriksson A (July 2017).
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is eventually resorbed naturally. Others can be treated by inserting a small
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Other risk factors include taking blood thinners (anticoagulants), long-term
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remove surrounding collagen, providing space for new blood vessels to grow.
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Mezue WC, Ndubuisi CA, Chikani MC, Achebe DS, Ohaegbulam SC (July 2012).
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through a hole drilled through the skull and sucking out the hematoma.
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due to the substances released from the hematoma, which causes further
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Subdural hematomas occur most often around the tops and sides of the
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Oishi M, Toyama M, Tamatani S, Kitazawa T, Saito M (August 2001).
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They are also commonly seen in the elderly and in people with an
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Ko BS, Lee JK, Seo BR, Moon SJ, Kim JH, Kim SH (January 2008).
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Chinese Journal of Traumatology = Zhonghua Chuang Shang Za Zhi
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Ratilal BO, Pappamikail L, Costa J, Sampaio C (June 2013).
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surrounding the vein makes it susceptible to such tearing.
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Subdural hematoma as marked by the arrow with significant
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Rao MG, Singh D, Khandelwal N, Sharma SK (April 2016).
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Hematoma usually associated with traumatic brain injury
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and produces fragile and leaky blood vessels through
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will usually detect significant subdural hematomas.
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Imaging and Mechanism of Subdural Hematoma – MedPix
1620:"Chronic subdural hematoma – an up-to-date concept" 516:into the hematoma cavity. Traumatic tearing of the 2680: 323:, in which rapidly changing velocities within the 2219: 2205:: CS1 maint: DOI inactive as of September 2024 ( 1201:"Traumatic extradural hematoma in enugu, Nigeria" 177:. The third type of brain hemorrhage, known as a 4345: 154:Subdural hematomas may cause an increase in the 2269:Yadav YR, Parihar V, Namdev H, Bajaj J (2016). 2166: 2164: 1766: 1525:"Acute subdural haematoma : a reappraisal" 1507: 1078:Accessed through web archive on August 8, 2007. 648:or medial displacement of the junction between 640:like the tentorium cerebelli and falx cerebri. 455:is unleashed, and may ultimately lead to brain 747:Comparison of epidural and subdural hematomas 3905: 3761: 2666: 759: 335:, subdural hemorrhages generally result from 2262: 2213: 2161: 2126: 1873: 1871: 1460: 1458: 1018: 319:Subdural hematomas are most often caused by 2319: 2090:The Cochrane Database of Systematic Reviews 1677:Journal of Clinical and Diagnostic Research 1464: 1074:University of Vermont College of Medicine. 98:, long-term excessive alcohol consumption, 3912: 3898: 3768: 3754: 2983:Arrhythmogenic right ventricular dysplasia 2673: 2659: 2320:Chan DY, Sun TF, Poon WS (December 2015). 1719: 1665: 1663: 1617: 766: 752: 543:. Mediators that promote angiogenesis are 539:, while the anti-inflammatory mediator is 123:—usually but not always associated with a 2475: 2337: 2296: 2286: 2245: 2109: 1967: 1944: 1895: 1868: 1696: 1594: 1584: 1455: 1401: 1399: 1343: 1294: 1226: 1216: 1142: 1044: 917:Large or symptomatic hematomas require a 741: 719:, depending on the speed of their onset. 1100: 1098: 1096: 1094: 1092: 1090: 1088: 1086: 1084: 585: 577: 496:leads to new membrane formation through 477: 399:is a risk factor for subdural hematoma. 127:—gathers between the inner layer of the 33:Subdural haematoma, subdural haemorrhage 1877: 1660: 1025:Journal of Korean Neurosurgical Society 807:and inner meningeal layer of dura mater 4346: 2717:Spontaneous coronary artery dissection 1627:Journal of Medical and Dental Sciences 1522: 1512:(4th ed.). New York: Morgan Hill. 1501: 1396: 825:Temperoparietal locus (most likely) – 601:examination, after any head trauma. A 590:Chronic subdural after treatment with 582:A subdural hematoma demonstrated by CT 214:or fluctuating levels of consciousness 3893: 3776:Nonmusculoskeletal injuries of head ( 3749: 2654: 1081: 1070: 1068: 1066: 1064: 857:Symptoms (depending on the severity) 711:Subdural hematomas are classified as 386:. As the brain shrinks with age, the 296:Hearing loss or ringing in the ears ( 188: 4164:Partial anterior circulation infarct 3041:Nonbacterial thrombotic endocarditis 1272: 1270: 1120: 1118: 1076:"Neuropathology: Trauma to the CNS." 1014: 1012: 1010: 1008: 2386: 309:, or abnormal movement of the eyes. 143:. It usually results from tears in 119:) is a type of bleeding in which a 13: 4159:Total anterior circulation infarct 3960:Posterior cerebral artery syndrome 3337:Accelerated idioventricular rhythm 1061: 549:vascular endothelial growth factor 466:rises, blood is squeezed into the 417: 14: 4370: 3950:Anterior cerebral artery syndrome 2504: 1267: 1115: 1005: 706: 555:promotes the expression of VEGF. 524:also causes continuous bleeding. 4333:Cerebral venous sinus thrombosis 2456:Surgical Neurology International 810:Between the meningeal layers of 236:(either constant or fluctuating) 38: 4111:Anterior spinal artery syndrome 3955:Middle cerebral artery syndrome 3022:Subacute bacterial endocarditis 2362: 2313: 2077: 2033: 1990: 1961: 1912: 1851: 1826: 1809: 1740: 1713: 1611: 1516: 1419: 1360: 377: 169:are usually caused by tears in 2102:10.1002/14651858.CD004893.pub3 1618:Tanaka Y, Ohno K (June 2013). 1416:. Retrieved on August 7, 2007. 1319: 1243: 1192: 1167: 658: 1: 4116:Vertebrobasilar insufficiency 3539:Pulseless electrical activity 3468:Multifocal atrial tachycardia 3342:Catecholaminergic polymorphic 2326:Chinese Neurosurgical Journal 2275:Asian Journal of Neurosurgery 2055:10.1016/S0140-6736(09)61115-6 2011:10.1016/S0140-6736(09)61682-2 1884:Archives of Internal Medicine 1407:"Tutorial: CT in head trauma" 998: 929:, new or recurrent bleeding, 404:excessive alcohol consumption 2238:10.1001/jamaneurol.2018.2030 1897:10.1001/archinte.158.15.1617 1689:10.7860/JCDR/2016/17207.7644 1573:Journal of Neuroinflammation 1332:Neurologia Medico-Chirurgica 1106:Imaging in Subdural Hematoma 957: 901: 573: 504:, permitting the leakage of 7: 2271:"Chronic subdural hematoma" 1937:10.1016/j.cjtee.2019.05.006 1205:Nigerian Journal of Surgery 971: 947:HMG-CoA reductase inhibitor 941:are harmful or beneficial. 699:Fresh subdural bleeding is 327:may stretch and tear small 10: 4375: 4085:Cerebellar stroke syndrome 4018:Lateral medullary syndrome 3483:Wandering atrial pacemaker 3030:non-infective endocarditis 2971:Endocardial fibroelastosis 2147:10.1016/j.wneu.2015.08.044 1834:"Acute Subdural Hematomas" 1441:10.1089/089771502760341938 1382:10.3171/jns.2003.98.6.1217 473: 293:Altered breathing patterns 4320: 4310:Charcot–Bouchard aneurysm 4295: 4275: 4257: 4239: 4213: 4204: 4174: 4154:Transient ischemic attack 4131: 4121:Subclavian steal syndrome 4093: 4075: 4013:Medial medullary syndrome 4003:Brainstem stroke syndrome 3993: 3940: 3931: 3871: 3846: 3815: 3804: 3785: 3700: 3643: 3561:hexaxial reference system 3552: 3519: 3506:Jervell and Lange-Nielsen 3491: 3449: 3408: 3385: 3359: 3327: 3285: 3266: 3165: 3151: 3051: 3036:Libman–Sacks endocarditis 3005: 2991: 2907: 2856: 2849: 2786: 2741: 2698: 2689: 2595: 2512: 2339:10.1186/s41016-015-0005-4 1979:. WETA-TV. Archived from 1817:Subdural Hematoma Surgery 1753:Loyola University Chicago 1586:10.1186/s12974-017-0881-y 1037:10.3340/jkns.2008.43.1.11 832:anterior ethmoidal artery 620:. They also occur in the 557:Matrix metalloproteinases 412:cerebrospinal fluid leaks 314: 156:pressure inside the skull 89: 70: 54: 46: 37: 29: 24: 4359:Cerebrovascular diseases 4192:Transient global amnesia 4039:Lateral pontine syndrome 3975:Dejerine–Roussy syndrome 3921:Cerebrovascular diseases 3441:Ventricular fibrillation 2712:Coronary artery aneurysm 2288:10.4103/1793-5482.145102 1523:Tandon PN (March 2001). 1479:10.3171/2013.10.JNS13272 1218:10.4103/1117-6806.103111 436:Intracerebral hemorrhage 422: 360:antiplatelet medications 331:. Much more common than 104:cerebrospinal fluid leak 4283:Intracranial hemorrhage 4101:Carotid artery stenosis 4030:Medial pontine syndrome 3879:Penetrating head injury 3718:Diastolic heart failure 3692:Athletic heart syndrome 3653:Ventricular hypertrophy 3387:Pre-excitation syndrome 3241:Left posterior fascicle 2766:Acute coronary syndrome 2706:Coronary artery disease 2187:(inactive 2024-09-12). 1859:Penetrating Head Trauma 1467:Journal of Neurosurgery 1370:Journal of Neurosurgery 1144:10.3171/2014.6.JNS14550 1131:Journal of Neurosurgery 846:superior sagittal sinus 827:Middle meningeal artery 622:posterior cranial fossa 287:, or difficulty walking 179:subarachnoid hemorrhage 3236:Left anterior fascicle 3016:infective endocarditis 2801:Hibernating myocardium 2682:Cardiovascular disease 2185:10.4414/smw.2017.14398 1968:McDonough VT, King B. 1722:"Subdural haemorrhage" 1720:Sharma R, Gaillard F. 1429:Journal of Neurotrauma 993:Intra-axial hemorrhage 988:Extra-axial hemorrhage 742:Differential diagnosis 732:diffuse brain injuries 594: 583: 489: 290:Loss of muscle control 125:traumatic brain injury 4305:Intracranial aneurysm 4094:Extracranial arteries 3400:Wolff–Parkinson–White 3360:Premature contraction 3258:Adams–Stokes syndrome 2961:Loeffler endocarditis 2771:Myocardial infarction 2468:10.25259/SNI_240_2022 2374:neurosurgery.ucla.edu 1787:10.1148/rg.2019190076 983:Diffuse axonal injury 923:intracranial pressure 869:Gradually increasing 589: 581: 567:intracranial aneurysm 481: 464:intracranial pressure 350:who have evidence of 203:intracranial pressure 162:if properly managed. 4241:Cerebral/Intra-axial 4187:Binswanger's disease 3567:Right axis deviation 3529:Sudden cardiac death 2887:Pericardial effusion 2830:Ventricular aneurysm 2399:Neurosurgical Review 2173:Swiss Medical Weekly 634:sutures of the skull 468:dural venous sinuses 348:alcohol use disorder 341:shaken baby syndrome 333:epidural hemorrhages 4328:Cerebral vasculitis 4206:Haemorrhagic stroke 4144:Cerebral infarction 3572:Left axis deviation 3429:Atrial fibrillation 3424:Ventricular flutter 3347:Torsades de pointes 3221:Bundle branch block 3180:Sick sinus syndrome 2966:Cardiac amyloidosis 2951:Tachycardia-induced 2806:Myocardial stunning 2754:Prinzmetal's angina 2723:Coronary thrombosis 2049:(9695): 1067–1073. 2005:(9695): 1040–1041. 773: 724:cerebral contusions 630:tentorium cerebelli 449:biochemical cascade 372:cerebrospinal fluid 272:Personality changes 121:collection of blood 83:cerebrospinal fluid 4267:Duret haemorrhages 3859:Perforated eardrum 3675:Atrial enlargement 3473:Pacemaker syndrome 3395:Lown–Ganong–Levine 3317:Junctional ectopic 3312:AV nodal reentrant 2818:Myocardial rupture 2728:Coronary vasospasm 2596:External resources 2411:10.1007/BF01105894 2135:World Neurosurgery 1986:on 21 August 2010. 1878:Kushner D (1998). 1412:2005-11-06 at the 1345:10.2176/nmc.41.382 965:Glasgow Coma Scale 835:Occipital locus – 746: 656:—may be apparent. 595: 584: 490: 276:Inability to speak 195:Signs and symptoms 189:Signs and symptoms 167:epidural hematomas 4341: 4340: 4291: 4290: 4200: 4199: 4065:Claude's syndrome 4060:Benedikt syndrome 3887: 3886: 3867: 3866: 3743: 3742: 3735:Obstructive shock 3639: 3638: 3586:Short QT syndrome 3553:Other / ungrouped 3544:Sinoatrial arrest 3459:Ectopic pacemaker 3355: 3354: 3175:Sinus bradycardia 3147: 3146: 3143: 3142: 2892:Cardiac tamponade 2845: 2844: 2835:Dressler syndrome 2733:Myocardial bridge 2636:Subdural Hematoma 2630: 2629: 2232:(11): 1338–1346. 1890:(15): 1617–1624. 1648:on 13 August 2017 1296:10.1111/apa.13760 899: 898: 803:or between outer 697: 696: 638:dural reflections 510:white blood cells 390:enlarges and the 337:shearing injuries 113:subdural hematoma 109: 108: 25:Subdural hematoma 19:Medical condition 4366: 4249:Intraventricular 4211: 4210: 4055:Weber's syndrome 3980:Watershed stroke 3970:Moyamoya disease 3938: 3937: 3933:Ischaemic stroke 3914: 3907: 3900: 3891: 3890: 3838:Corneal abrasion 3813: 3812: 3770: 3763: 3756: 3747: 3746: 3708:Cardiac fibrosis 3600:T wave alternans 3493:Long QT syndrome 3287:Supraventricular 3283: 3282: 3216:Intraventricular 3163: 3162: 3003: 3002: 2854: 2853: 2699:Coronary disease 2696: 2695: 2675: 2668: 2661: 2652: 2651: 2510: 2509: 2498: 2497: 2479: 2447: 2438: 2437: 2435: 2433: 2390: 2384: 2383: 2381: 2380: 2366: 2360: 2359: 2341: 2317: 2311: 2310: 2300: 2290: 2266: 2260: 2259: 2249: 2217: 2211: 2210: 2204: 2196: 2168: 2159: 2158: 2141:(6): 1968–1972. 2130: 2124: 2123: 2113: 2081: 2075: 2074: 2037: 2031: 2030: 1994: 1988: 1987: 1985: 1974: 1965: 1959: 1958: 1948: 1916: 1910: 1909: 1899: 1875: 1866: 1855: 1849: 1848: 1846: 1844: 1830: 1824: 1813: 1807: 1806: 1781:(6): 1571–1595. 1770: 1764: 1763: 1761: 1760: 1744: 1738: 1737: 1735: 1734: 1717: 1711: 1710: 1700: 1683:(4): HC01–HC05. 1667: 1658: 1657: 1655: 1653: 1647: 1641:. Archived from 1624: 1615: 1609: 1608: 1598: 1588: 1564: 1555: 1554: 1549: 1547: 1520: 1514: 1513: 1505: 1499: 1498: 1473:(6): 1378–1384. 1462: 1453: 1452: 1435:(9): 1017–1027. 1423: 1417: 1405:Downie A. 2001. 1403: 1394: 1393: 1376:(6): 1217–1221. 1364: 1358: 1357: 1347: 1323: 1317: 1316: 1298: 1289:(7): 1021–1027. 1283:Acta Paediatrica 1274: 1265: 1264: 1262: 1261: 1255:Cleveland Clinic 1247: 1241: 1240: 1230: 1220: 1196: 1190: 1189: 1187: 1186: 1171: 1165: 1164: 1146: 1137:(6): 1380–1387. 1122: 1113: 1102: 1079: 1072: 1059: 1058: 1048: 1016: 830:Frontal locus – 822:Involved vessel 777:Compared quality 774: 768: 761: 754: 745: 690:After 10–14 days 659: 553:Prostaglandin E2 453:ischemic cascade 441:vasoconstriction 352:cerebral atrophy 269:Loss of appetite 139:surrounding the 42: 22: 21: 4374: 4373: 4369: 4368: 4367: 4365: 4364: 4363: 4344: 4343: 4342: 4337: 4316: 4287: 4271: 4253: 4235: 4196: 4170: 4127: 4089: 4071: 3989: 3965:Amaurosis fugax 3927: 3918: 3888: 3883: 3863: 3842: 3806: 3800: 3781: 3774: 3744: 3739: 3730:Rheumatic fever 3696: 3635: 3548: 3515: 3487: 3445: 3404: 3381: 3351: 3323: 3270: 3262: 3156: 3139: 3047: 2996: 2987: 2903: 2897:Hemopericardium 2841: 2782: 2776:Unstable angina 2749:Angina pectoris 2742:Active ischemia 2737: 2685: 2679: 2631: 2626: 2625: 2591: 2590: 2521: 2507: 2502: 2501: 2448: 2441: 2431: 2429: 2391: 2387: 2378: 2376: 2368: 2367: 2363: 2318: 2314: 2267: 2263: 2218: 2214: 2198: 2197: 2169: 2162: 2131: 2127: 2096:(6): CD004893. 2082: 2078: 2038: 2034: 1995: 1991: 1983: 1972: 1966: 1962: 1917: 1913: 1876: 1869: 1856: 1852: 1842: 1840: 1832: 1831: 1827: 1814: 1810: 1771: 1767: 1758: 1756: 1746: 1745: 1741: 1732: 1730: 1718: 1714: 1668: 1661: 1651: 1649: 1645: 1622: 1616: 1612: 1565: 1558: 1545: 1543: 1529:Neurology India 1521: 1517: 1506: 1502: 1463: 1456: 1424: 1420: 1414:Wayback Machine 1404: 1397: 1365: 1361: 1324: 1320: 1275: 1268: 1259: 1257: 1249: 1248: 1244: 1197: 1193: 1184: 1182: 1173: 1172: 1168: 1123: 1116: 1103: 1082: 1073: 1062: 1017: 1006: 1001: 974: 960: 939:anticonvulsants 904: 865:unconsciousness 844:Vertex locus – 843: 841:sigmoid sinuses 834: 829: 816:Arachnoid mater 772: 744: 715:, subacute, or 709: 624:, and near the 576: 565:for unruptured 518:arachnoid mater 506:red blood cells 476: 425: 420: 418:Pathophysiology 380: 317: 312: 191: 147:that cross the 133:arachnoid mater 81:, reduction in 20: 17: 12: 11: 5: 4372: 4362: 4361: 4356: 4339: 4338: 4336: 4335: 4330: 4324: 4322: 4318: 4317: 4315: 4314: 4313: 4312: 4301: 4299: 4293: 4292: 4289: 4288: 4286: 4285: 4279: 4277: 4273: 4272: 4270: 4269: 4263: 4261: 4255: 4254: 4252: 4251: 4245: 4243: 4237: 4236: 4234: 4233: 4228: 4223: 4217: 4215: 4208: 4202: 4201: 4198: 4197: 4195: 4194: 4189: 4184: 4178: 4176: 4172: 4171: 4169: 4168: 4167: 4166: 4161: 4156: 4149:Classification 4146: 4141: 4139:Brain ischemia 4135: 4133: 4132:Classification 4129: 4128: 4126: 4125: 4124: 4123: 4113: 4108: 4103: 4097: 4095: 4091: 4090: 4088: 4087: 4081: 4079: 4073: 4072: 4070: 4069: 4068: 4067: 4062: 4057: 4047: 4046: 4045: 4043:Millard-Gubler 4036: 4022: 4021: 4020: 4015: 4005: 3999: 3997: 3991: 3990: 3988: 3987: 3985:Lacunar stroke 3982: 3977: 3972: 3967: 3962: 3957: 3952: 3946: 3944: 3935: 3929: 3928: 3917: 3916: 3909: 3902: 3894: 3885: 3884: 3882: 3881: 3875: 3873: 3869: 3868: 3865: 3864: 3862: 3861: 3855: 3853: 3844: 3843: 3841: 3840: 3835: 3830: 3824: 3822: 3810: 3802: 3801: 3799: 3798: 3789: 3787: 3783: 3782: 3773: 3772: 3765: 3758: 3750: 3741: 3740: 3738: 3737: 3732: 3727: 3726: 3725: 3723:Cardiac asthma 3720: 3710: 3704: 3702: 3698: 3697: 3695: 3694: 3689: 3688: 3687: 3682: 3672: 3671: 3670: 3665: 3660: 3649: 3647: 3641: 3640: 3637: 3636: 3634: 3633: 3631:Strain pattern 3628: 3627: 3626: 3621: 3616: 3604: 3603: 3602: 3590: 3589: 3588: 3576: 3575: 3574: 3569: 3556: 3554: 3550: 3549: 3547: 3546: 3541: 3536: 3531: 3525: 3523: 3521:Cardiac arrest 3517: 3516: 3514: 3513: 3508: 3503: 3501:Andersen–Tawil 3497: 3495: 3489: 3488: 3486: 3485: 3480: 3475: 3470: 3465: 3455: 3453: 3447: 3446: 3444: 3443: 3438: 3437: 3436: 3426: 3421: 3419:Atrial flutter 3415: 3413: 3406: 3405: 3403: 3402: 3397: 3391: 3389: 3383: 3382: 3380: 3379: 3374: 3369: 3363: 3361: 3357: 3356: 3353: 3352: 3350: 3349: 3344: 3339: 3333: 3331: 3325: 3324: 3322: 3321: 3320: 3319: 3314: 3304: 3303: 3302: 3291: 3289: 3280: 3264: 3263: 3261: 3260: 3255: 3254: 3253: 3248: 3243: 3238: 3233: 3228: 3218: 3213: 3212: 3211: 3206: 3201: 3191: 3182: 3177: 3171: 3169: 3160: 3149: 3148: 3145: 3144: 3141: 3140: 3138: 3137: 3136: 3135: 3130: 3118: 3117: 3116: 3111: 3099: 3098: 3097: 3092: 3080: 3079: 3078: 3073: 3068: 3055: 3053: 3049: 3048: 3046: 3045: 3044: 3043: 3038: 3026: 3025: 3024: 3011: 3009: 3000: 2989: 2988: 2986: 2985: 2980: 2979: 2978: 2973: 2968: 2963: 2958: 2953: 2948: 2943: 2942: 2941: 2929:Cardiomyopathy 2926: 2925: 2924: 2922:Chagas disease 2913: 2911: 2905: 2904: 2902: 2901: 2900: 2899: 2894: 2884: 2883: 2882: 2873: 2862: 2860: 2851: 2847: 2846: 2843: 2842: 2840: 2839: 2838: 2837: 2832: 2822: 2821: 2820: 2810: 2809: 2808: 2803: 2792: 2790: 2784: 2783: 2781: 2780: 2779: 2778: 2773: 2763: 2762: 2761: 2756: 2745: 2743: 2739: 2738: 2736: 2735: 2730: 2725: 2720: 2714: 2709: 2702: 2700: 2693: 2687: 2686: 2678: 2677: 2670: 2663: 2655: 2649: 2648: 2643: 2628: 2627: 2624: 2623: 2612: 2600: 2599: 2597: 2593: 2592: 2589: 2588: 2577: 2566: 2565:- nontraumatic 2546: 2522: 2517: 2516: 2514: 2513:Classification 2506: 2505:External links 2503: 2500: 2499: 2439: 2405:(4): 239–244. 2385: 2361: 2312: 2281:(4): 330–342. 2261: 2226:JAMA Neurology 2212: 2160: 2125: 2076: 2032: 1989: 1960: 1931:(5): 286–289. 1911: 1867: 1850: 1825: 1808: 1765: 1739: 1712: 1659: 1610: 1556: 1515: 1500: 1454: 1418: 1395: 1359: 1338:(8): 382–386. 1318: 1266: 1242: 1191: 1166: 1114: 1080: 1060: 1003: 1002: 1000: 997: 996: 995: 990: 985: 980: 973: 970: 959: 956: 903: 900: 897: 896: 890: 885: 878: 877: 867: 861:Lucid interval 858: 854: 853: 851:Bridging veins 848: 823: 819: 818: 808: 795:and the inner 789: 785: 784: 781: 778: 771: 770: 763: 756: 748: 743: 740: 728:mortality rate 708: 707:Classification 705: 695: 694: 691: 687: 686: 683: 679: 678: 675: 671: 670: 663: 618:parietal lobes 575: 572: 541:Interleukin 10 475: 472: 424: 421: 419: 416: 397:arachnoid cyst 388:subdural space 379: 376: 356:anticoagulants 329:bridging veins 316: 313: 311: 310: 304: 303:Blurred vision 301: 294: 291: 288: 282: 280:slurred speech 273: 270: 267: 258: 252: 247: 245:Disorientation 242: 237: 231: 226: 223: 218: 215: 207: 190: 187: 149:subdural space 145:bridging veins 107: 106: 93: 87: 86: 72: 68: 67: 58: 52: 51: 44: 43: 35: 34: 31: 27: 26: 18: 15: 9: 6: 4: 3: 2: 4371: 4360: 4357: 4355: 4352: 4351: 4349: 4334: 4331: 4329: 4326: 4325: 4323: 4319: 4311: 4308: 4307: 4306: 4303: 4302: 4300: 4298: 4294: 4284: 4281: 4280: 4278: 4274: 4268: 4265: 4264: 4262: 4260: 4256: 4250: 4247: 4246: 4244: 4242: 4238: 4232: 4229: 4227: 4224: 4222: 4219: 4218: 4216: 4212: 4209: 4207: 4203: 4193: 4190: 4188: 4185: 4183: 4180: 4179: 4177: 4173: 4165: 4162: 4160: 4157: 4155: 4152: 4151: 4150: 4147: 4145: 4142: 4140: 4137: 4136: 4134: 4130: 4122: 4119: 4118: 4117: 4114: 4112: 4109: 4107: 4104: 4102: 4099: 4098: 4096: 4092: 4086: 4083: 4082: 4080: 4078: 4074: 4066: 4063: 4061: 4058: 4056: 4053: 4052: 4051: 4048: 4044: 4040: 4037: 4035: 4031: 4028: 4027: 4026: 4023: 4019: 4016: 4014: 4011: 4010: 4009: 4006: 4004: 4001: 4000: 3998: 3996: 3992: 3986: 3983: 3981: 3978: 3976: 3973: 3971: 3968: 3966: 3963: 3961: 3958: 3956: 3953: 3951: 3948: 3947: 3945: 3943: 3939: 3936: 3934: 3930: 3926: 3922: 3915: 3910: 3908: 3903: 3901: 3896: 3895: 3892: 3880: 3877: 3876: 3874: 3870: 3860: 3857: 3856: 3854: 3852: 3850: 3845: 3839: 3836: 3834: 3831: 3829: 3826: 3825: 3823: 3821: 3819: 3814: 3811: 3809: 3808:facial trauma 3805:Extracranial/ 3803: 3797: 3796: 3791: 3790: 3788: 3784: 3779: 3771: 3766: 3764: 3759: 3757: 3752: 3751: 3748: 3736: 3733: 3731: 3728: 3724: 3721: 3719: 3716: 3715: 3714: 3713:Heart failure 3711: 3709: 3706: 3705: 3703: 3699: 3693: 3690: 3686: 3683: 3681: 3678: 3677: 3676: 3673: 3669: 3666: 3664: 3661: 3659: 3656: 3655: 3654: 3651: 3650: 3648: 3646: 3642: 3632: 3629: 3625: 3624:ST depression 3622: 3620: 3617: 3615: 3612: 3611: 3610: 3609: 3605: 3601: 3598: 3597: 3596: 3595: 3591: 3587: 3584: 3583: 3582: 3581: 3577: 3573: 3570: 3568: 3565: 3564: 3563: 3562: 3558: 3557: 3555: 3551: 3545: 3542: 3540: 3537: 3535: 3532: 3530: 3527: 3526: 3524: 3522: 3518: 3512: 3509: 3507: 3504: 3502: 3499: 3498: 3496: 3494: 3490: 3484: 3481: 3479: 3476: 3474: 3471: 3469: 3466: 3464: 3460: 3457: 3456: 3454: 3452: 3448: 3442: 3439: 3435: 3432: 3431: 3430: 3427: 3425: 3422: 3420: 3417: 3416: 3414: 3412: 3407: 3401: 3398: 3396: 3393: 3392: 3390: 3388: 3384: 3378: 3375: 3373: 3370: 3368: 3365: 3364: 3362: 3358: 3348: 3345: 3343: 3340: 3338: 3335: 3334: 3332: 3330: 3326: 3318: 3315: 3313: 3310: 3309: 3308: 3305: 3301: 3298: 3297: 3296: 3293: 3292: 3290: 3288: 3284: 3281: 3278: 3274: 3269: 3265: 3259: 3256: 3252: 3251:Trifascicular 3249: 3247: 3244: 3242: 3239: 3237: 3234: 3232: 3229: 3227: 3224: 3223: 3222: 3219: 3217: 3214: 3210: 3207: 3205: 3202: 3200: 3197: 3196: 3195: 3192: 3190: 3186: 3183: 3181: 3178: 3176: 3173: 3172: 3170: 3168: 3164: 3161: 3159: 3154: 3150: 3134: 3133:regurgitation 3131: 3129: 3126: 3125: 3124: 3123: 3119: 3115: 3114:regurgitation 3112: 3110: 3107: 3106: 3105: 3104: 3100: 3096: 3095:regurgitation 3093: 3091: 3088: 3087: 3086: 3085: 3081: 3077: 3076:regurgitation 3074: 3072: 3069: 3067: 3064: 3063: 3062: 3061: 3057: 3056: 3054: 3050: 3042: 3039: 3037: 3034: 3033: 3032: 3031: 3027: 3023: 3020: 3019: 3018: 3017: 3013: 3012: 3010: 3008: 3004: 3001: 2999: 2994: 2990: 2984: 2981: 2977: 2974: 2972: 2969: 2967: 2964: 2962: 2959: 2957: 2954: 2952: 2949: 2947: 2944: 2940: 2937: 2936: 2935: 2932: 2931: 2930: 2927: 2923: 2920: 2919: 2918: 2915: 2914: 2912: 2910: 2906: 2898: 2895: 2893: 2890: 2889: 2888: 2885: 2881: 2877: 2874: 2872: 2869: 2868: 2867: 2864: 2863: 2861: 2859: 2855: 2852: 2848: 2836: 2833: 2831: 2828: 2827: 2826: 2823: 2819: 2816: 2815: 2814: 2811: 2807: 2804: 2802: 2799: 2798: 2797: 2794: 2793: 2791: 2789: 2785: 2777: 2774: 2772: 2769: 2768: 2767: 2764: 2760: 2759:Stable angina 2757: 2755: 2752: 2751: 2750: 2747: 2746: 2744: 2740: 2734: 2731: 2729: 2726: 2724: 2721: 2718: 2715: 2713: 2710: 2707: 2704: 2703: 2701: 2697: 2694: 2692: 2688: 2683: 2676: 2671: 2669: 2664: 2662: 2657: 2656: 2653: 2647: 2644: 2642: 2638: 2637: 2633: 2632: 2622: 2618: 2617: 2613: 2611: 2607: 2606: 2602: 2601: 2598: 2594: 2587: 2583: 2582: 2578: 2576: 2572: 2571: 2567: 2564: 2561:- traumatic; 2560: 2556: 2555: 2551: 2547: 2545: 2541: 2537: 2533: 2532: 2528: 2524: 2523: 2520: 2515: 2511: 2495: 2491: 2487: 2483: 2478: 2473: 2469: 2465: 2461: 2457: 2453: 2446: 2444: 2428: 2424: 2420: 2416: 2412: 2408: 2404: 2400: 2396: 2389: 2375: 2371: 2365: 2357: 2353: 2349: 2345: 2340: 2335: 2331: 2327: 2323: 2316: 2308: 2304: 2299: 2294: 2289: 2284: 2280: 2276: 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674:First hours 650:gray matter 321:head injury 75:Head injury 30:Other names 4348:Categories 4077:Cerebellum 3995:Brain stem 3923:including 3833:Eye injury 3780:) and neck 3409:Flutter / 3372:Junctional 3307:Junctional 3300:Multifocal 3273:paroxysmal 3189:Sinoatrial 3158:arrhythmia 3153:Conduction 2909:Myocardium 2581:DiseasesDB 2379:2019-02-19 2179:: w14398. 1759:2018-01-06 1733:2018-08-14 1669:Fig 3 in: 1579:(1): 108. 1260:2022-03-10 1185:2012-07-27 999:References 978:Concussion 919:craniotomy 908:blood clot 837:transverse 812:dura mater 801:dura mater 701:hyperdense 592:burr holes 563:Craniotomy 483:Micrograph 457:cell death 362:, such as 129:dura mater 96:Senescence 79:alcoholism 4259:Brainstem 4034:Foville's 3828:Black eye 3668:Pulmonary 3451:Pacemaker 3122:pulmonary 3103:tricuspid 2939:Alcoholic 2641:eMedicine 2621:neuro/575 2616:eMedicine 2494:249359877 2348:2057-4967 1977:BrainLine 1864:eMedicine 1822:eMedicine 1803:203926019 1161:207731566 1111:eMedicine 958:Prognosis 931:infection 902:Treatment 875:confusion 805:endosteal 797:meningeal 788:Location 783:Subdural 574:Diagnosis 487:HPS stain 240:Dizziness 183:pia mater 160:prognosis 65:Neurology 56:Specialty 4297:Aneurysm 4226:Subdural 4221:Epidural 4050:Midbrain 3534:Asystole 3434:Familial 3128:stenosis 3109:stenosis 3090:stenosis 3071:stenosis 3066:prolapse 2788:Sequelae 2691:Ischemia 2486:35855136 2427:29824615 2332:(1): 2. 2307:27695533 2256:30073290 2193:28102879 2155:26342776 2120:23744552 2063:19782872 2027:29932520 2019:19782854 1955:31521457 1795:31589576 1707:27190831 1639:23918031 1605:28558815 1541:11303234 1495:25404949 1487:24313607 1449:12482115 1410:Archived 1390:12816267 1354:11561348 1305:28130787 1237:24027399 1153:25036203 1055:19096538 972:See also 949:such as 935:seizures 925:, brain 912:catheter 895:-shaped 893:Crescent 871:headache 814:and the 780:Epidural 607:MRI scan 551:(VEGF). 498:fibrosis 445:ischemia 430:collagen 408:dementia 364:warfarin 298:tinnitus 265:vomiting 256:lethargy 234:Headache 229:Numbness 221:Seizures 210:Loss of 171:arteries 137:meninges 131:and the 100:dementia 85:pressure 4276:General 4182:CADASIL 4008:Medulla 2934:Dilated 2876:Chronic 2684:(heart) 2575:D006408 2477:9282733 2462:: 230. 2419:9457718 2356:3934313 2298:4974954 2247:6248109 2111:7388908 2071:5206569 1946:6823676 1906:9701095 1843:21 July 1698:4866129 1596:5450087 1313:4435564 1228:3762009 1046:2588154 882:CT scan 717:chronic 614:frontal 603:CT scan 474:Chronic 368:aspirin 250:Amnesia 135:of the 3925:stroke 3614:J wave 3367:Atrial 3295:Atrial 3084:aortic 3060:mitral 3052:Valves 2998:valves 2850:Layers 2719:(SCAD) 2610:000713 2492:  2484:  2474:  2425:  2417:  2354:  2346:  2305:  2295:  2254:  2244:  2191:  2153:  2118:  2108:  2069:  2061:  2043:Lancet 2025:  2017:  1999:Lancet 1953:  1943:  1904:  1801:  1793:  1705:  1695:  1637:  1603:  1593:  1539:  1493:  1485:  1447:  1388:  1352:  1311:  1303:  1235:  1225:  1159:  1151:  1053:  1043:  933:, and 535:, and 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Index


midline shift
Specialty
Neurosurgery
Neurology
Head injury
alcoholism
cerebrospinal fluid
Risk factors
Senescence
dementia
cerebrospinal fluid leak
collection of blood
traumatic brain injury
dura mater
arachnoid mater
meninges
brain
bridging veins
subdural space
pressure inside the skull
prognosis
epidural hematomas
arteries
skull
subarachnoid hemorrhage
pia mater
Signs and symptoms
intracranial pressure
consciousness

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