317:
398:
330:
382:
370:
358:
243:
177:
146:
346:
29:
316:
225:
Warthin's tumor primarily affects older individuals (age 60–70 years). There is a slight male predilection according to recent studies. The tumor is slow growing, painless, and usually appears in the tail of the parotid gland near the angle of the
322:
This
Warthin's tumor presented as a parotid mass in a middle-aged male, who underwent superficial parotidectomy. The tumor, at the right of the image, is well-demarcated from the adjacent parotid tissue and tends to shell out from
804:
789:
369:
290:
cells with abundant, granular, eosinophilic cytoplasm. The cystic spaces have epithelium referred to as papillary infoldings that protrude into them. Additionally, the epithelium has lymphoid stroma with
357:
397:
1548:
329:
819:
1541:
381:
230:. In 5–14% of cases, Warthin's tumor is bilateral, but the two masses usually are at different times. Warthin's tumor is highly unlikely to become
541:
530:- Chan MKM, McGuire LJ: Cytodiagnosis of Lesions Presenting as Salivary Gland Swellings: A Report of Seven Cases. Diagn Cytopathol 8: 439-443, 1992b.
746:
510:
1534:
345:
254:. In fact, it is the only tumor virtually restricted to the parotid gland. Warthin's tumor is the second most common benign parotid tumor after
912:
93:
65:
1634:
375:
Histopathology of
Warthin tumor in the parotid gland. Higher magnification of a file "Warthin tumor (1).jpg". H&E stain.
1387:
72:
46:
1629:
956:
905:
1749:
679:
553:
112:
363:
Histopathology of
Warthin tumor in the parotid gland. Another view of a file "Warthin tumor (1).jpg". H&E stain.
1639:
1437:
79:
624:
1441:
1274:
1526:
1062:
50:
61:
1379:
898:
1168:
1426:
1343:
976:
1483:
1465:
1375:
1326:
1754:
1460:
1383:
1220:
1046:
1009:
176:
1619:
1614:
1488:
1421:
1356:
1230:
1210:
1177:
1155:
1117:
827:
270:. Smokers are at 8 times greater risk of developing Warthin's tumor than the general population.
1624:
1590:
966:
156:
of
Warthin's tumor, with typical cellular features (and a relatively uncommon binucleated cell).
39:
1349:
1173:
1113:
303:
299:
86:
625:"Warthin's tumour seems to be the most common benign neoplasm of the parotid gland in Germany"
1609:
1511:
1235:
740:
521:
504:
1724:
1573:
1339:
1198:
1135:
971:
951:
214:
8:
1659:
1475:
1127:
961:
808:
602:
438:
426:
255:
1308:
1140:
1103:
981:
723:
696:
652:
487:
462:
242:
17:
878:
813:
1452:
838:
728:
675:
656:
644:
578:
549:
492:
418:
165:
145:
522:"A correlative cytological and histopathological study on lesions of salivary gland"
1413:
1331:
1145:
1057:
718:
708:
636:
542:"Chapter 9 "Benign tumors, cysts, and tumor-like conditions of the salivary glands"
482:
474:
210:
890:
1556:
1431:
1094:
832:
460:
292:
267:
202:
1182:
1108:
1037:
843:
640:
570:
227:
1743:
422:
251:
153:
798:
713:
1366:
1318:
1262:
1163:
732:
648:
582:
496:
246:
Relative incidence of parotid tumors, with
Warthin's tumor near top right.
1711:
1706:
1698:
1581:
1565:
1304:
1079:
991:
478:
206:
781:
763:
Kahn, Michael A. Basic Oral and
Maxillofacial Pathology. Volume 1. 2001.
1684:
1215:
1084:
1074:
930:
404:
388:
336:
307:
287:
279:
266:
Its cause is unknown, but there is a strong association with cigarette
1267:
1203:
943:
939:
873:
849:
282:
is unique. There are cystic spaces surrounded by two uniform rows of
231:
157:
351:
Histopathology of
Warthin tumor in the parotid gland. H&E stain.
28:
1557:
697:"Oncocytic lesion of parotid gland: A dilemma for cytopathologists"
407:
of a
Warthin tumor showing the characteristic bilayered epithelium.
283:
170:
854:
1569:
1225:
1032:
1004:
1502:
1295:
1089:
922:
793:
194:
694:
1023:
198:
622:
463:"Cytomorphological findings in diagnosis of Warthin tumor"
461:
Köybaşioğlu FF, Önal B, Han Ü, Adabağ A, Şahpaz A (2020).
1561:
623:
Psychogios G, Vlastos I, Thölken R, Zenk J (July 2020).
546:
Salivary Gland
Diseases: Surgical and Medical Management
1031:
457:
Image by Mikael Häggström, MD. References for entries:
213:(lymph node-like stroma). It is named for pathologist
771:
548:. New York: Thieme Medical Publishers. p. 123.
920:
53:. Unsourced material may be challenged and removed.
674:(7th ed.). St. Louis, MO: Elsevier Saunders.
339:of a Warthin tumor arising from the parotid gland.
139:Warthin tumour, monomorphic adenoma, adenolymphoma
1741:
669:
577:, Treasure Island (FL): StatPearls Publishing,
672:Robbins and Cotran pathologic basis of disease
1542:
906:
519:
258:, but its prevalence is steadily increasing.
745:: CS1 maint: multiple names: authors list (
509:: CS1 maint: multiple names: authors list (
688:
600:
568:
1549:
1535:
913:
899:
629:European Archives of Oto-Rhino-Laryngology
175:
144:
722:
712:
486:
113:Learn how and when to remove this message
241:
695:Chakrabarti I, Basu A, Ghosh N (2012).
594:
278:The appearance of this tumor under the
1742:
663:
417:Most of these tumors are treated with
250:The gland most likely affected is the
1635:Polymorphous low-grade adenocarcinoma
1530:
894:
757:
569:Limaiem, Faten; Jain, Prachi (2023),
220:
670:Kumar V, Abbas AK, Fausto N (2005).
539:
51:adding citations to reliable sources
22:
1388:Papillary serous cystadenocarcinoma
217:, who described two cases in 1929.
191:papillary cystadenoma lymphomatosum
13:
1630:Epithelial-myoepithelial carcinoma
957:Combined small-cell lung carcinoma
14:
1766:
767:
1640:Hyalinizing clear cell carcinoma
601:Steve C Lee (22 December 2022).
396:
380:
368:
356:
344:
328:
315:
27:
1275:Syringocystadenoma papilliferum
38:needs additional citations for
1063:Familial adenomatous polyposis
616:
562:
533:
451:
1:
1438:Paget's disease of the breast
1380:Pancreatic serous cystadenoma
444:
1442:Extramammary Paget's disease
1169:Multiple endocrine neoplasia
613:Diagrams by Mikael Häggström
520:Dr.S. Malliga (2006-10-18).
412:
273:
237:
7:
1601:malignant epithelial tumors
1427:Pancreatic ductal carcinoma
1344:Mucinous cystadenocarcinoma
977:Transitional cell carcinoma
432:
387:Intermediate magnification
10:
1771:
1484:Medullary breast carcinoma
1466:Invasive lobular carcinoma
1376:Ovarian serous cystadenoma
1327:Signet ring cell carcinoma
641:10.1007/s00405-020-05894-z
603:"Salivary Gland Neoplasms"
15:
1720:
1697:
1673:
1648:
1598:
1589:
1580:
1501:
1474:
1461:Lobular carcinoma in situ
1451:
1412:
1401:
1384:Serous cystadenocarcinoma
1365:
1317:
1294:
1283:
1248:
1221:Clear-cell adenocarcinoma
1191:
1154:
1126:
1045:
1022:
1010:Bartholin gland carcinoma
990:
938:
929:
921:Glandular and epithelial
864:
775:
164:
152:
143:
135:
130:
1750:Salivary gland neoplasia
1651:benign epithelial tumors
1620:Adenoid cystic carcinoma
1615:Mucoepidermoid carcinoma
1489:Medullary thyroid cancer
1422:Mammary ductal carcinoma
1357:Mucoepidermoid carcinoma
1211:Adenoid cystic carcinoma
1178:Adrenocortical carcinoma
1118:Hepatocellular carcinoma
261:
16:Not to be confused with
1625:Salivary duct carcinoma
967:Squamous-cell carcinoma
714:10.4103/0970-9371.93236
429:, it is non recurrent.
1350:Pseudomyxoma peritonei
1174:Adrenocortical adenoma
1114:Hepatocellular adenoma
304:sebaceous lymphadenoma
300:differential diagnosis
247:
1610:Acinic cell carcinoma
1512:Acinic cell carcinoma
1236:Papillary hidradenoma
611:Updated: Jan 13, 2021
540:Witt RL, ed. (2005).
245:
1574:head and neck cancer
1340:Mucinous cystadenoma
1199:Neuroendocrine tumor
1136:Renal cell carcinoma
972:Basal-cell carcinoma
952:Small-cell carcinoma
479:10.3906/sag-1901-215
215:Aldred Scott Warthin
205:containing abundant
47:improve this article
1660:Pleomorphic adenoma
1476:Medullary carcinoma
962:Verrucous carcinoma
439:Pleomorphic adenoma
427:pleomorphic adenoma
403:High magnification
391:of a Warthin tumor.
256:pleomorphic adenoma
1309:Cystadenocarcinoma
1141:Endometrioid tumor
1104:Cholangiocarcinoma
992:Complex epithelial
982:Inverted papilloma
865:External resources
758:Additional sources
335:Low magnification
248:
221:Signs and symptoms
1737:
1736:
1733:
1732:
1693:
1692:
1524:
1523:
1520:
1519:
1497:
1496:
1453:Lobular carcinoma
1397:
1396:
1244:
1243:
1018:
1017:
888:
887:
184:
183:
125:Medical condition
123:
122:
115:
97:
62:"Warthin's tumor"
1762:
1755:Benign neoplasms
1678:
1653:
1603:
1596:
1595:
1587:
1586:
1551:
1544:
1537:
1528:
1527:
1444:
1414:Ductal carcinoma
1410:
1409:
1390:
1346:
1332:Krukenberg tumor
1292:
1291:
1146:Renal oncocytoma
1058:Linitis plastica
1047:Gastrointestinal
1043:
1042:
1029:
1028:
936:
935:
915:
908:
901:
892:
891:
773:
772:
751:
750:
744:
736:
726:
716:
692:
686:
685:
667:
661:
660:
635:(7): 2081–2084.
620:
614:
610:
598:
592:
591:
590:
589:
566:
560:
559:
537:
531:
528:
526:
514:
508:
500:
490:
455:
419:surgical removal
400:
384:
372:
360:
348:
332:
319:
211:germinal centers
189:, also known as
180:
179:
148:
128:
127:
118:
111:
107:
104:
98:
96:
55:
31:
23:
1770:
1769:
1765:
1764:
1763:
1761:
1760:
1759:
1740:
1739:
1738:
1729:
1716:
1689:
1674:
1669:
1665:Warthin's tumor
1649:
1644:
1599:
1576:
1555:
1525:
1516:
1493:
1470:
1447:
1436:
1432:Comedocarcinoma
1405:
1403:
1393:
1374:
1361:
1338:
1313:
1287:
1285:
1279:
1250:
1240:
1187:
1150:
1122:
1095:Somatostatinoma
1038:adenocarcinomas
1036:
1014:
1000:Warthin's tumor
986:
925:
919:
889:
884:
883:
860:
859:
784:
770:
760:
755:
754:
738:
737:
693:
689:
682:
668:
664:
621:
617:
612:
599:
595:
587:
585:
571:"Warthin Tumor"
567:
563:
556:
538:
534:
529:
524:
517:
515:
502:
501:
458:
456:
452:
447:
435:
415:
408:
401:
392:
385:
376:
373:
364:
361:
352:
349:
340:
333:
324:
320:
293:germinal center
276:
264:
240:
223:
203:salivary glands
187:Warthin's tumor
174:
131:Warthin's tumor
126:
119:
108:
102:
99:
56:
54:
44:
32:
21:
12:
11:
5:
1768:
1758:
1757:
1752:
1735:
1734:
1731:
1730:
1728:
1727:
1721:
1718:
1717:
1715:
1714:
1709:
1703:
1701:
1695:
1694:
1691:
1690:
1688:
1687:
1681:
1679:
1671:
1670:
1668:
1667:
1662:
1656:
1654:
1646:
1645:
1643:
1642:
1637:
1632:
1627:
1622:
1617:
1612:
1606:
1604:
1593:
1591:Salivary gland
1584:
1578:
1577:
1554:
1553:
1546:
1539:
1531:
1522:
1521:
1518:
1517:
1515:
1514:
1508:
1506:
1499:
1498:
1495:
1494:
1492:
1491:
1486:
1480:
1478:
1472:
1471:
1469:
1468:
1463:
1457:
1455:
1449:
1448:
1446:
1445:
1434:
1429:
1424:
1418:
1416:
1407:
1399:
1398:
1395:
1394:
1392:
1391:
1371:
1369:
1363:
1362:
1360:
1359:
1354:
1353:
1352:
1336:
1335:
1334:
1323:
1321:
1315:
1314:
1312:
1311:
1301:
1299:
1289:
1281:
1280:
1278:
1277:
1272:
1271:
1270:
1265:
1254:
1252:
1251:skin appendage
1246:
1245:
1242:
1241:
1239:
1238:
1233:
1228:
1223:
1218:
1213:
1208:
1207:
1206:
1195:
1193:
1192:Other/multiple
1189:
1188:
1186:
1185:
1180:
1171:
1166:
1160:
1158:
1152:
1151:
1149:
1148:
1143:
1138:
1132:
1130:
1124:
1123:
1121:
1120:
1111:
1109:Klatskin tumor
1106:
1100:
1099:
1098:
1097:
1092:
1087:
1082:
1077:
1066:
1065:
1060:
1051:
1049:
1040:
1026:
1020:
1019:
1016:
1015:
1013:
1012:
1007:
1002:
996:
994:
988:
987:
985:
984:
979:
974:
969:
964:
959:
954:
948:
946:
933:
927:
926:
918:
917:
910:
903:
895:
886:
885:
882:
881:
869:
868:
866:
862:
861:
858:
857:
846:
835:
824:
816:
801:
785:
780:
779:
777:
776:Classification
769:
768:External links
766:
765:
764:
759:
756:
753:
752:
687:
680:
662:
615:
593:
561:
554:
532:
473:(1): 148–154.
467:Turk J Med Sci
449:
448:
446:
443:
442:
441:
434:
431:
425:. Contrary to
414:
411:
410:
409:
402:
395:
393:
386:
379:
377:
374:
367:
365:
362:
355:
353:
350:
343:
341:
334:
327:
325:
321:
314:
275:
272:
263:
260:
239:
236:
222:
219:
182:
181:
168:
162:
161:
150:
149:
141:
140:
137:
133:
132:
124:
121:
120:
35:
33:
26:
18:Wharton's duct
9:
6:
4:
3:
2:
1767:
1756:
1753:
1751:
1748:
1747:
1745:
1726:
1723:
1722:
1719:
1713:
1710:
1708:
1705:
1704:
1702:
1700:
1696:
1686:
1683:
1682:
1680:
1677:
1672:
1666:
1663:
1661:
1658:
1657:
1655:
1652:
1647:
1641:
1638:
1636:
1633:
1631:
1628:
1626:
1623:
1621:
1618:
1616:
1613:
1611:
1608:
1607:
1605:
1602:
1597:
1594:
1592:
1588:
1585:
1583:
1579:
1575:
1571:
1567:
1563:
1559:
1552:
1547:
1545:
1540:
1538:
1533:
1532:
1529:
1513:
1510:
1509:
1507:
1504:
1500:
1490:
1487:
1485:
1482:
1481:
1479:
1477:
1473:
1467:
1464:
1462:
1459:
1458:
1456:
1454:
1450:
1443:
1439:
1435:
1433:
1430:
1428:
1425:
1423:
1420:
1419:
1417:
1415:
1411:
1408:
1406:and medullary
1400:
1389:
1385:
1381:
1377:
1373:
1372:
1370:
1368:
1364:
1358:
1355:
1351:
1348:
1347:
1345:
1341:
1337:
1333:
1330:
1329:
1328:
1325:
1324:
1322:
1320:
1316:
1310:
1306:
1303:
1302:
1300:
1297:
1293:
1290:
1282:
1276:
1273:
1269:
1266:
1264:
1261:
1260:
1259:
1256:
1255:
1253:
1247:
1237:
1234:
1232:
1229:
1227:
1224:
1222:
1219:
1217:
1214:
1212:
1209:
1205:
1202:
1201:
1200:
1197:
1196:
1194:
1190:
1184:
1181:
1179:
1175:
1172:
1170:
1167:
1165:
1162:
1161:
1159:
1157:
1153:
1147:
1144:
1142:
1139:
1137:
1134:
1133:
1131:
1129:
1125:
1119:
1115:
1112:
1110:
1107:
1105:
1102:
1101:
1096:
1093:
1091:
1088:
1086:
1083:
1081:
1078:
1076:
1073:
1072:
1071:
1068:
1067:
1064:
1061:
1059:
1056:
1053:
1052:
1050:
1048:
1044:
1041:
1039:
1034:
1030:
1027:
1025:
1021:
1011:
1008:
1006:
1003:
1001:
998:
997:
995:
993:
989:
983:
980:
978:
975:
973:
970:
968:
965:
963:
960:
958:
955:
953:
950:
949:
947:
945:
941:
937:
934:
932:
928:
924:
916:
911:
909:
904:
902:
897:
896:
893:
880:
876:
875:
871:
870:
867:
863:
856:
852:
851:
847:
845:
841:
840:
836:
834:
830:
829:
825:
822:
821:
817:
815:
811:
810:
806:
802:
800:
796:
795:
791:
787:
786:
783:
778:
774:
762:
761:
748:
742:
734:
730:
725:
720:
715:
710:
706:
702:
698:
691:
683:
681:0-7216-0187-1
677:
673:
666:
658:
654:
650:
646:
642:
638:
634:
630:
626:
619:
608:
604:
597:
584:
580:
576:
572:
565:
557:
555:1-58890-414-8
551:
547:
543:
536:
523:
516:Binucleation:
512:
506:
498:
494:
489:
484:
480:
476:
472:
468:
464:
454:
450:
440:
437:
436:
430:
428:
424:
423:parotidectomy
420:
406:
399:
394:
390:
383:
378:
371:
366:
359:
354:
347:
342:
338:
331:
326:
318:
313:
312:
311:
309:
305:
301:
296:
294:
289:
285:
281:
271:
269:
259:
257:
253:
252:parotid gland
244:
235:
233:
229:
218:
216:
212:
208:
204:
200:
196:
192:
188:
178:
172:
169:
167:
163:
159:
155:
154:Cytopathology
151:
147:
142:
138:
134:
129:
117:
114:
106:
95:
92:
88:
85:
81:
78:
74:
71:
67:
64: –
63:
59:
58:Find sources:
52:
48:
42:
41:
36:This article
34:
30:
25:
24:
19:
1675:
1664:
1650:
1600:
1263:Hidrocystoma
1257:
1183:Hürthle cell
1164:Prolactinoma
1069:
1054:
999:
872:
848:
837:
826:
818:
803:
788:
741:cite journal
704:
700:
690:
671:
665:
632:
628:
618:
606:
596:
586:, retrieved
574:
564:
545:
535:
505:cite journal
470:
466:
453:
416:
297:
286:, which are
277:
265:
249:
224:
190:
186:
185:
109:
103:January 2022
100:
90:
83:
76:
69:
57:
45:Please help
40:verification
37:
1712:Rhabdomyoma
1707:Leukoplakia
1582:Oral cancer
1566:oral cavity
1305:Cystadenoma
1258:sweat gland
1249:Adnexal and
1080:Glucagonoma
879:plastic/371
707:(1): 80–2.
295:formation.
207:lymphocytes
136:Other names
1744:Categories
1725:Oropharynx
1685:Oncocytoma
1288:and serous
1231:Cylindroma
1216:Oncocytoma
1128:Urogenital
1085:Gastrinoma
1075:Insulinoma
931:Epithelium
839:DiseasesDB
588:2023-11-03
575:StatPearls
445:References
405:micrograph
389:micrograph
337:micrograph
308:oncocytoma
288:epithelial
280:microscope
73:newspapers
1676:ungrouped
1286:mucinous,
1268:Syringoma
1204:Carcinoid
1156:Endocrine
944:carcinoma
940:Papilloma
874:eMedicine
855:422470007
850:SNOMED CT
657:212940703
413:Treatment
302:includes
284:oncocytes
274:Diagnosis
238:Locations
232:malignant
166:Specialty
158:Pap stain
1404:lobular,
1319:Mucinous
1070:pancreas
1033:Adenomas
823:: 8561/0
733:22438628
649:32189070
607:Medscape
583:32491572
497:31769640
433:See also
228:mandible
171:Oncology
1570:pharynx
1402:Ductal,
1298:general
1284:Cystic,
1226:Apudoma
1005:Thymoma
833:D000235
724:3307464
701:J Cytol
488:7080357
421:called
268:smoking
201:of the
197:cystic
193:, is a
87:scholar
1699:Tongue
1558:Tumors
1503:Acinar
1367:Serous
1296:Cystic
1090:VIPoma
1055:tract:
1024:Glands
923:cancer
731:
721:
678:
655:
647:
581:
552:
495:
485:
195:benign
173:
89:
82:
75:
68:
60:
844:31941
820:ICD-O
814:210.2
653:S2CID
525:(PDF)
262:Cause
199:tumor
94:JSTOR
80:books
1568:and
1505:cell
828:MeSH
809:9-CM
747:link
729:PMID
676:ISBN
645:PMID
579:PMID
550:ISBN
511:link
493:PMID
306:and
298:The
209:and
66:news
1562:lip
1560:of
805:ICD
799:D11
790:ICD
719:PMC
709:doi
637:doi
633:277
483:PMC
475:doi
323:it.
49:by
1746::
1572:/
1564:,
1440:/
1386:/
1382:/
1378:/
1342:/
877::
853::
842::
831::
812::
797::
794:10
743:}}
739:{{
727:.
717:.
705:29
703:.
699:.
651:.
643:.
631:.
627:.
605:.
573:,
544:.
518:-
507:}}
503:{{
491:.
481:.
471:50
469:.
465:.
459:-
310:.
234:.
1550:e
1543:t
1536:v
1307:/
1176:/
1116:/
1035:/
942:/
914:e
907:t
900:v
807:-
792:-
782:D
749:)
735:.
711::
684:.
659:.
639::
609:.
558:.
527:.
513:)
499:.
477::
160:.
116:)
110:(
105:)
101:(
91:·
84:·
77:·
70:·
43:.
20:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
