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Wellcome Sanger Institute

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953: 246: 254: 716: 2757: 2195: 1909: 1594: 544:, a collaboration with scientists around the globe, signalled an effort to sequence the genomes of 1000 individuals in order to create the "most detailed map of human genetic variation to support disease studies". The data from the pilot projects was made freely available in public databases in June 2010. In 2010, the Sanger Institute announced its participation in the UK10K project, which will sequence the genomes of 10,000 individuals to identify rare genetic variants and their effects on human health. The Sanger Institute is also part of the 319: 4571: 3977: 482: 3989: 4142: 1004:, in the US, to take up the position as director of the Sanger Institute. Bradley wanted to build on the achievements made by the Sanger Institute in the Human Genome Project by "concentrating on gene function, cancer genomics, and the genomes of model organisms such as the mouse and the zebrafish". Bradley received his BA, MA and PhD in genetics from the University of Cambridge. 1660:
Cunningham, F; Amode, M. R.; Barrell, D; Beal, K; Billis, K; Brent, S; Carvalho-Silva, D; Clapham, P; Coates, G; Fitzgerald, S; Gil, L; Girón, C. G.; Gordon, L; Hourlier, T; Hunt, S. E.; Janacek, S. H.; Johnson, N; Juettemann, T; Kähäri, A. K.; Keenan, S; Martin, F. J.; Maurel, T; McLaren, W; Murphy,
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The institute operates two PhD training programmes: a four-year course for basic science graduates, and a three-year course for clinicians. The four-year course requires students to rotate around three different laboratories in order to broaden their scientific horizons before choosing a PhD project.
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Harris, T. W.; Baran, J; Bieri, T; Cabunoc, A; Chan, J; Chen, W. J.; Davis, P; Done, J; Grove, C; Howe, K; Kishore, R; Lee, R; Li, Y; Muller, H. M.; Nakamura, C; Ozersky, P; Paulini, M; Raciti, D; Schindelman, G; Tuli, M. A.; Van Auken, K; Wang, D; Wang, X; Williams, G; Wong, J. D.; Yook, K; Schedl,
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Logan-Klumpler, F. J.; De Silva, N; Boehme, U; Rogers, M. B.; Velarde, G; McQuillan, J. A.; Carver, T; Aslett, M; Olsen, C; Subramanian, S; Phan, I; Farris, C; Mitra, S; Ramasamy, G; Wang, H; Tivey, A; Jackson, A; Houston, R; Parkhill, J; Holden, M; Harb, O. S.; Brunk, B. P.; Myler, P. J.; Roos, D;
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The Communication and Public Engagement programme aims to "encourage informed discussion about issues relevant to Sanger Institute research" and "foster a community of researchers who can engage effectively with different audiences". The institute hosts visits for more than 1,500 students, teachers
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Explores human gene function by studying the impact of genome variation on cell biology. Large-scale systematic screens are used to discover the impact of naturally occurring and engineered genome mutations in human induced pluripotent cells (hIPSCs), their differentiated derivatives and other cell
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Scientific research at the Sanger Institute is organised into five Scientific Programmes, each defining a major area of research with a particular biological, disease or analytic focus. The current Programmes at the Sanger Institute are Cancer, Ageing and Somatic Mutation, Cellular Genetics, Human
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Since 2000, the institute expanded its mission to understand "the role of genetics in health and disease". The institute now employs around 900 people and engages in five main areas of research: Cancer, Ageing and Somatic Mutation; Cellular Genetics; Human Genetics; Parasite and Microbes; and the
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The Tree of Life Programme was created in 2019 to investigate the diversity of complex organisms found in the UK through sequencing and cellular technologies. It also compares and contrasts species' genome sequences to unlock insights into evolution and conservation. This Programme will play a
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Provides leadership in data aggregation and informatics innovation, develops high-throughput cellular models of cancer for genome-wide functional screens and drug testing, and explores somatic mutation's role in clonal evolution, ageing and development. This Programme includes the
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According to Companies House the five officers of the parent company Genome Research Limited are Henry Parkinson, Kay Elizabeth Davies, Rolf Dieter Heuer, James Cuthbert Smith, David Lindsay Willetts. According to the Sanger website Henry Parkinson is head of legal.
265:. This 55-acre (220,000 m) site was to become the Wellcome Genome Campus, which has a growing population of around 1300 staff, approximately 900 of whom work at the Sanger Institute. The Genome Campus also includes the Wellcome Trust Conference Centre and the 976:
was the founding director of the Sanger Institute. Sulston was instrumental in the choice of the Hinxton site for the institute and remained there as director until the announcement of the completion of the draft human genome in 2000. Sulston graduated from the
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The Programme applies genomics to population-scale studies to identify the causal variants and pathways involved in human disease and their effects on cell biology. It also models developmental disorders to explore which physical aspects might be reversible.
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Genetics, Parasites and Microbes and Tree of Life. Studies from all programmes provide insights into human, pathogen, cellular evolution, the phenotypic and hence biological consequences of genome variation and the processes which cause mutations.
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samples each week. The institute "capitalises on leading-edge technologies to answer questions unanswerable only a few years ago". The advances in technology allow the Sanger Institute to carry out sequencing of the genomes of individual humans,
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and community groups per year. Visitors may meet scientific staff, tour the institute and its facilities, and participate in ethical debates and activities. The programme also offers professional development sessions for teachers of
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interactions, in particular host response to infection and the role of microiotia in health and disease. All the genomes after sequencing are made available at the web-based onsite-maintained database, GeneDB.
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In October 2019 it was reported that the institute had manufactured a medical tool with the intent of monetising it despite not having ethical nor legal approval to do so and having been made aware by
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Each student is required to choose at least one experimental and one informatics-based rotation project. The institute houses approximately 50 pre-doctoral students, all of whom are registered at the
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activity. The programme aims to make complex biomedical research accessible to a range of audiences including school students and their teachers, and local community members.
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In August 2018 it was reported that an investigation was under way into allegations of bullying of staff and gender discrimination made against senior management of the
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Forbes, S. A.; Beare, D; Gunasekaran, P; Leung, K; Bindal, N; Boutselakis, H; Ding, M; Bamford, S; Cole, C; Ward, S; Kok, C. Y.; Jia, M; De, T; Teague, J. W.;
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Nawrocki, E. P.; Burge, S. W.; Bateman, A; Daub, J; Eberhardt, R. Y.; Eddy, S. R.; Floden, E. W.; Gardner, P. P.; Jones, T. A.; Tate, J; Finn, R. D. (2015).
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databases resources are one of the outcomes of research programmes that the Sanger Institute is involved in. Those hosted by the Sanger Institute include:
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Commemorative stain window located in the Sulston building of the Wellcome Sanger Institute, to mark the opening of the Genome Campus
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Investigates the common underpinning mechanisms of evolution, infection and resistance to therapy into bolster understanding of
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leading role in the Darwin Tree of Life Project, a UK-wide initiative to sequence the genomes of all 66,000 complex species (
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Scientific and public engagement staff also collaborate on and contribute to national projects such as the UK's
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and staff amenities. In discussing the name of the centre, Sanger (still alive when the centre was opened) told
4127: 3692: 663: 269:. A major extension of the campus was officially opened in 2005; the buildings accommodate new laboratories, a 2530: 2105:"1000 Genomes Project releases data from pilot projects on path to providing database for 2,500 human genomes" 1325: 4291: 3612: 3529: 3497: 2926:"Changing of the guard: Allan Bradley is to head the Sanger Centre, a powerhouse of the Human Genome Project" 1273: 1242: 1119: 961: 2817: 4020: 3942: 3461: 3400: 2347: 647: 4450: 4220: 4168: 3570: 3493: 3435: 873: 1039:, published in 2004. The institute was engaged in collaborations to sequence 8 of the 23 human pairs of 4390: 3550: 2708: 1001: 952: 1355: 512:
types. It is one of the founder programmes driving the creation and organisation of the international
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into the Sanger Institute is also offered for Science Learning Centres, Science Centres and schools.
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International Conference on Computational Intelligence Methods for Bioinformatics and Biostatistics
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Children at a public outreach event thread bracelets in four colours to spell out a DNA sequence.
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In 1993 the then 17 Sanger Centre staff moved into temporary laboratory space at Hinxton Hall in
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in 1963 and completed his PhD on the chemical synthesis of DNA in 1966. He shared the 2002
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Wilming, L. G.; Gilbert, J. G.; Howe, K; Trevanion, S; Hubbard, T; Harrow, J. L. (2008).
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Please help update this article to reflect recent events or newly available information.
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Several databases were initiated at the Sanger Institute but are now hosted elsewhere:
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Microsoft Research - University of Trento Centre for Computational and Systems Biology
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Much of the Sanger Institute's research is carried out in partnership with the wider
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D. N.; Nag, R; Overduin, B; Parker, A; Patricio, M; Perry, E; et al. (2015).
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The Sanger Institute was opened in 1993, three years after the inception of the
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The Common Thread: A story of Science, Politics, Ethics, and the Human Genome
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Gibbs, Richard A.; et al. (The International HapMap Consortium) (2003).
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The Wellcome Trust Sanger Institute was established in 1992, funded by the
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Schreiber, F; Patricio, M; Muffato, M; Pignatelli, M; Bateman, A (2014).
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As of 2023 the Sanger employs more than a thousand people, and is led by
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in health and disease. Aside from the institute's contribution to the
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Carrington, M; Smith, D. F.; Hertz-Fowler, C; Berriman, M (2012).
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In 2010, Bradley stepped down from his leadership role to form a
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research programmes to create an encyclopaedia of DNA elements.
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Rawlings, N. D.; Waller, M; Barrett, A. J.; Bateman, A (2014).
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Bragin, E; Chatzimichali, E. A.; Wright, C. F.; Hurles, M. E.;
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It is located on the Wellcome Genome Campus by the village of
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African Society for Bioinformatics and Computational Biology
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Sainsbury Wellcome Centre for Neural Circuits and Behaviour
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Max Planck Institute of Molecular Cell Biology and Genetics
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Figure based on data for 2008 retrieved from SCOPUS website
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The Sanger Institute's sequencing staff handle millions of
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Buildings and structures in South Cambridgeshire District
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v9: A new website, more species and orthology-on-the-fly"
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The Morgan Building (right), part of the Sanger Institute
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International Nucleotide Sequence Database Collaboration
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and post 16 science through the national network of
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Partner institutions of the University of Cambridge
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(2014). 896:Previous faculty members at the Sanger include: 452:, a database on the biology and sequence of the 4184:Coalition for Epidemic Preparedness Innovations 3772:International Society for Computational Biology 3190:Marsh, Sarah; Devlin, Hannah (29 August 2018). 2603: 1495:"Wellcome Sanger Institute - Pathogen genomics" 1406:(2008). "Big data: Welcome to the petacentre". 3839:ISCB Africa ASBCB Conference on Bioinformatics 3250: 2611:"Parkinson, Henry - Wellcome Sanger Institute" 1713:"GeneDB--an annotation database for pathogens" 1263: 506: 4021: 3786:Institute of Genomics and Integrative Biology 3401: 1862:; Clements, J; Coggill, P; Eberhardt, R. Y.; 494:Cancer, Ageing and Somatic Mutation Programme 3815:European Conference on Computational Biology 2816:. National Human Genome Research Institute. 1322:"Wellcome Sanger Institute - Work and study" 859: 467:, a database for the genomics for parasitic 182:research institute, primarily funded by the 3850:Research in Computational Molecular Biology 3189: 3089:Human Genome Sequencing Consortium (2004). 2909:. Wellcome Sanger Institute. Archived from 2661:. Wellcome Sanger Institute. Archived from 2262:. Wellcome Sanger Institute. Archived from 2186:: CS1 maint: numeric names: authors list ( 2130:Kaye, J; Hurles, M; Griffin, H; Grewal, J; 2107:. Wellcome Sanger Institute. Archived from 1611:; Bevan, A. P.; Swaminathan, G. J. (2014). 1497:. Wellcome Sanger Institute. Archived from 1298:. Wellcome Sanger Institute. Archived from 1296:"Wellcome Trust Sanger Institute - History" 804:As of 2019 a faculty of 32 scientists lead 519: 235: 4611:Genetics or genomics research institutions 4028: 4014: 3827:International Conference on Bioinformatics 3408: 3394: 2694:Logan, D. W.; Sandal, M.; Gardner, P. P.; 2553:"Wellcome Sanger Institute PhD Programmes" 2288:. International Cancer Genome Consortium. 1396: 884:, Professor Kevin Marsh and Professor Sir 658:International Mouse Phenotyping Consortium 370:, a database of chromosomal imbalance and 4606:Genetic engineering in the United Kingdom 3821:Intelligent Systems for Molecular Biology 3313: 3158: 3137: 3114: 3039: 2998: 2941: 2789: 2769: 2739: 2729: 2382: 2235: 2225: 2163: 2054: 2000: 1947: 1891: 1834: 1785: 1736: 1686: 1636: 1576: 1214: 1173: 1000:left his appointment as professor at the 600: 399:, a vertebrate genome annotation resource 4556:Wellcome Trust Principal Research Fellow 2704:"Ten Simple Rules for Editing Knowledge" 2415:"Programmes - Wellcome Sanger Institute" 1600: 1551:; McDermott, U; Campbell, P. J. (2015). 1469:"Wellcome Sanger Institute - Sequencing" 1402: 1352:Wellcome Genome Campus Conference Centre 951: 723:The Sanger Institute has a programme of 714: 480: 252: 244: 3809:Basel Computational Biology Conference‎ 3253:"Thomas Kibling's Investigatory Report" 3021: 2633: 1026: 653:International Knockout Mouse Consortium 308: 4588: 4081:WTC for Gene Regulation and Expression 2881:"Sanger Institute looks to the future" 2669: 1288: 1239:"Wellcome Sanger Institute - About us" 1196: 1144: 1021:International Cancer Genome Consortium 643:International Cancer Genome Consortium 546:International Cancer Genome Consortium 4621:Research institutes in Cambridgeshire 4560:Wellcome Trust Senior Research Fellow 4009: 3766:International Society for Biocuration 3664:European Molecular Biology Laboratory 3389: 2861:from the original on 15 November 2015 2843:. The Joseph Henry Press. p. 18. 2345: 2085:from the original on 18 December 2008 1868:"Pfam: The protein families database" 1199:"Sequences, Sequences, and Sequences" 705:The UK 10,000 Genomes Project (UK10K) 540:. In January 2008, the launch of the 471:(both Nematodes and Platyhelminthes). 4525:Institutional Strategic Support Fund 3988: 3352:from the original on 16 October 2019 3287: 3232:from the original on 17 January 2019 3070:from the original on 2 February 2013 2972: 2923: 2820:from the original on 13 January 2009 2687: 2597:"GENOME RESEARCH LIMITED - Officers" 2533:from the original on 29 October 2010 2473:from the original on 20 October 2008 2292:from the original on 4 December 2020 1528:from the original on 10 October 2010 1519: 761: 710: 312: 208:. It was conceived as a large scale 3792:Japanese Society for Bioinformatics 3202:from the original on 29 August 2018 2651: 2425:from the original on 8 October 2010 2031:2014: New views of curated biology" 1440: 1328:from the original on 8 October 2010 1216:10.1146/annurev.bi.57.070188.000245 799: 528:focuses on the characterisation of 224:, and does much of its research in 197:. It shares this location with the 16:British genomics research institute 13: 4035: 3754:European Molecular Biology network 3415: 3251:Thomas Kibling (31 October 2018). 2621:from the original on 27 April 2021 2503:from the original on 11 April 2018 2348:"The International HapMap Project" 2144:European Journal of Human Genetics 2134:; Timpson, N; Smee, C; Bolton, P; 1276:from the original on 11 April 2020 374:in humans, using Ensembl resources 14: 4637: 3844:Pacific Symposium on Biocomputing 3748:Australia Bioinformatics Resource 3715:Swiss Institute of Bioinformatics 3698:Netherlands Bioinformatics Centre 3658:European Bioinformatics Institute 3368: 3269:from the original on 4 April 2019 2559:from the original on 6 March 2009 1449:from the original on 4 March 2016 669:The Copy Number Variation Project 613: 267:European Bioinformatics Institute 199:European Bioinformatics Institute 4570: 4569: 4140: 3987: 3976: 3975: 3646:Database Center for Life Science 3634:Computational Biology Department 3522:Arabidopsis Information Resource 2883:. Genome Biology. Archived from 2755: 2677:"Previous faculty at the Sanger" 2318:from the original on 2 July 2010 2193: 1907: 1592: 1475:from the original on 7 July 2010 1384:from the original on 11 May 2008 1358:from the original on 18 May 2014 1126:from the original on 21 May 2012 872:whose members include Professor 584:, with a particular interest in 568:Pathogens and Microbes Programme 317: 27: 4519:Collaborative Awards in Science 4231:Malawi Liverpool Wellcome Trust 3492:Specialised genomic databases: 3338: 3288:Else, Holly (8 November 2018). 3281: 3244: 3214: 3183: 3131: 3082: 3056: 3015: 2966: 2917: 2899: 2873: 2847: 2832: 2806: 2763: 2589: 2571: 2545: 2515: 2485: 2453:(the UK 10,000 Genomes Project) 2437: 2407: 2339: 2330: 2304: 2278: 2252: 2201: 2123: 2097: 2071: 2017: 1964: 1915: 1851: 1802: 1753: 1703: 1653: 1540: 1513: 1487: 1461: 1245:from the original on 3 May 2021 1085:Wellcome Trust Sanger Institute 985:in Physiology or Medicine with 168:Wellcome Trust Sanger Institute 4522:Investigator Awards in Science 4128:Wellcome Research Laboratories 4093:WTC for Molecular Parasitology 4090:WTC for Mitochondrial Research 3693:Japanese Institute of Genetics 1623:(Database issue): D993–D1000. 1370: 1340: 1314: 1257: 1231: 1190: 1138: 1108: 1078: 664:Single nucleotide polymorphism 639:(ENCyclopedia Of DNA Elements) 552:types. It is also part of the 305:of raw sequence data per day. 1: 3613:Rosalind (education platform) 3530:Zebrafish Information Network 3498:Saccharomyces Genome Database 3066:. Wellcome Sanger Institute. 2579:"Sanger PhD and MPhil theses" 2555:. Wellcome Sanger Institute. 2469:. Wellcome Sanger Institute. 1471:. Wellcome Sanger Institute. 1443:"Interview with John Sulston" 1380:. Wellcome Sanger Institute. 1324:. Wellcome Sanger Institute. 1241:. Wellcome Sanger Institute. 1203:Annual Review of Biochemistry 1101: 1098:and internal whistleblowers. 968: 868:are guided by the scientific 796:and alumni are listed below: 750:traveling exhibition and the 280: 212:centre to participate in the 4076:WTC for Cell-Matrix Research 3943:List of biological databases 3462:Protein Information Resource 3160:10.1126/science.300.5618.409 2731:10.1371/journal.pcbi.1000941 792:. Notable scientific staff, 648:International HapMap Project 524:The institute's research in 461:and other related Nematodes. 7: 4221:Genome Reference Consortium 4169:Cambridge Biomedical Campus 3436:European Nucleotide Archive 2839:Sulston J, Ferry G (2002). 2770:van Ommen, Gertjan (2010). 2041:(Database issue): D789–93. 1878:(Database issue): D222–30. 1772:(Database issue): D753–60. 1723:(Database issue): D98–108. 1563:(Database issue): D805–11. 774: 507:Cellular Genetics Programme 476: 10: 4642: 4102:WTC for Stem Cell Research 3315:10.1038/d41586-018-07339-4 2709:PLOS Computational Biology 1987:(Database issue): D922–5. 1934:(Database issue): D130–7. 1821:(Database issue): D503–9. 1673:(Database issue): D662–9. 1002:Baylor College of Medicine 947: 249:The Wellcome Genome Campus 4567: 4509: 4418: 4383: 4329:Executive leadership team 4328: 4279: 4149: 4138: 4115: 4107:Wellcome Sanger Institute 4050: 4043: 3971: 3925: 3859: 3801: 3734: 3721:Wellcome Sanger Institute 3675:J. Craig Venter Institute 3621: 3599: 3538: 3423: 2907:"Professor Allan Bradley" 1015:, who is a leader of the 891: 860:Scientific advisory board 326:This section needs to be 240: 160:Wellcome Sanger Institute 140: 103: 81: 71: 63: 53: 43: 35: 26: 22:Wellcome Sanger Institute 4071:Science Learning Centres 3704:Philippine Genome Center 2081:. 1000 Genomes Project. 1120:Medical Research Council 962:Medical Research Council 783: 737:Science Learning Centres 610:) in the British Isles. 520:Human Genetics Programme 236:Facilities and resources 4528:Science Strategic Award 4287:Eliza Manningham-Buller 4150:Projects and facilities 4058:Francis Crick Institute 3948:Molecular phylogenetics 3444:China National GeneBank 2659:"Sanger Advisory Board" 2523:"Home - Science Museum" 1522:"Feature: Highly cited" 1096:Stellenbosch University 979:University of Cambridge 769:University of Cambridge 530:human genetic variation 4510:Awards and fellowships 4261:Wellcome Genome Campus 4189:COSMIC cancer database 4086:WTC for Human Genetics 4044:Centres and institutes 3652:DNA Data Bank of Japan 3440:DNA Data Bank of Japan 2035:Nucleic Acids Research 1981:Nucleic Acids Research 1928:Nucleic Acids Research 1872:Nucleic Acids Research 1815:Nucleic Acids Research 1766:Nucleic Acids Research 1717:Nucleic Acids Research 1667:Nucleic Acids Research 1617:Nucleic Acids Research 1557:Nucleic Acids Research 965: 924:Leena Peltonen-Palotie 720: 601:Tree of Life Programme 486: 446:trees for animal genes 391:Mouse Genetics Project 258: 250: 162:, previously known as 76:Wellcome Genome Campus 4552:Wellcome Trust Centre 4549:Wellcome Image Awards 4174:Cancer Genome Project 3933:Computational biology 3448:Secondary databases: 2156:10.1038/ejhg.2013.290 1017:Cancer Genome Project 955: 919:King's College London 718: 538:evolutionary genetics 501:Cancer Genome Project 484: 256: 248: 4226:Human Genome Project 4199:Diamond Light Source 4157:1000 Genomes Project 4097:WTC for Neuroimaging 3430:Sequence databases: 1264:www-core (webteam). 1033:Human Genome Project 1027:Human Genome Project 701:Human Genome Project 628:1000 Genomes Project 620:scientific community 542:1000 Genomes Project 534:Human Genome Project 309:Scientific resources 214:Human Genome Project 125:52.07750°N 0.18750°E 4545:Wellcome Book Prize 4537:Sir Henry Wellcome 4256:Wellcome Collection 3726:Whitehead Institute 3514:Rat Genome Database 3306:2018Natur.563..304E 3228:. 31 October 2018. 3116:10.1038/nature03001 3107:2004Natur.431..931H 3022:Dickson, D (2000). 2991:2001Natur.413R.660A 2722:2010PLSCB...6E0941L 2375:10.1038/nature02168 2367:2003Natur.426..789G 2047:10.1093/nar/gkt1063 1993:10.1093/nar/gkt1055 1940:10.1093/nar/gku1063 1884:10.1093/nar/gkt1223 1729:10.1093/nar/gkr1032 1679:10.1093/nar/gku1010 1569:10.1093/nar/gku1075 1197:Sanger, F. (1988). 1166:2014Natur.505...27W 866:Board of Management 810:Dominic Kwiatkowski 364:mutations in cancer 121: /  23: 4352:Peter Pereira Gray 4280:Board of governors 3963:Sequence alignment 3670:Flatiron Institute 2887:on 19 January 2004 2449:2010-07-19 at the 1827:10.1093/nar/gkt953 1778:10.1093/nar/gkm987 1629:10.1093/nar/gkt937 1524:. Wellcome Trust. 1501:on 21 October 2015 966: 935:Eleftheria Zeggini 850:Antonio Vidal-Puig 756:The Science Museum 721: 487: 259: 251: 21: 4583: 4582: 4297:Tobias Bonhoeffer 4136: 4135: 4003: 4002: 3958:Sequence database 3472:Protein Data Bank 3466:Other databases: 3300:(7731): 304–305. 3101:(7011): 931–945. 2647:on 16 March 2015. 2361:(6968): 789–796. 846:Stephen O'Rahilly 762:Graduate training 741:Videoconferencing 725:public engagement 711:Public engagement 674:genome sequencing 465:WormBase ParaSite 387:sequence database 360:, a catalogue of 347: 346: 164:The Sanger Centre 156: 155: 130:52.07750; 0.18750 4633: 4573: 4572: 4419:Other key people 4384:Former directors 4358:Chonnettia Jones 4292:Michael Ferguson 4266:Wellcome Library 4144: 4063:Gurdon Institute 4048: 4047: 4030: 4023: 4016: 4007: 4006: 3991: 3990: 3979: 3978: 3938:List of biobanks 3902:Stockholm format 3710:Scripps Research 3410: 3403: 3396: 3387: 3386: 3382: 3379: 3377: 3362: 3361: 3359: 3357: 3342: 3336: 3335: 3317: 3285: 3279: 3278: 3276: 3274: 3268: 3260:Sanger Institute 3257: 3248: 3242: 3241: 3239: 3237: 3226:Sanger Institute 3218: 3212: 3211: 3209: 3207: 3187: 3181: 3180: 3162: 3135: 3129: 3128: 3118: 3086: 3080: 3079: 3077: 3075: 3060: 3054: 3053: 3043: 3041:10.1038/35012766 3019: 3013: 3012: 3002: 3000:10.1038/35099707 2973:Adam, D (2001). 2970: 2964: 2963: 2945: 2943:10.1038/35013238 2924:Gura, T (2000). 2921: 2915: 2914: 2913:on 7 April 2015. 2903: 2897: 2896: 2894: 2892: 2877: 2871: 2870: 2868: 2866: 2851: 2845: 2844: 2836: 2830: 2829: 2827: 2825: 2810: 2804: 2803: 2793: 2767: 2761: 2760: 2759: 2753: 2743: 2733: 2691: 2685: 2684: 2683:on 7 April 2015. 2679:. Archived from 2673: 2667: 2666: 2665:on 7 April 2015. 2655: 2649: 2648: 2643:. Archived from 2641:"Sanger Faculty" 2637: 2631: 2630: 2628: 2626: 2615:www.sanger.ac.uk 2607: 2601: 2600: 2593: 2587: 2586: 2585:on 7 April 2015. 2581:. Archived from 2575: 2569: 2568: 2566: 2564: 2549: 2543: 2542: 2540: 2538: 2519: 2513: 2512: 2510: 2508: 2497:insidedna.org.uk 2489: 2483: 2482: 2480: 2478: 2463: 2454: 2441: 2435: 2434: 2432: 2430: 2419:www.sanger.ac.uk 2411: 2405: 2404: 2386: 2352: 2343: 2337: 2334: 2328: 2327: 2325: 2323: 2308: 2302: 2301: 2299: 2297: 2282: 2276: 2275: 2273: 2271: 2256: 2250: 2249: 2239: 2229: 2205: 2199: 2198: 2197: 2191: 2185: 2177: 2167: 2127: 2121: 2120: 2118: 2116: 2101: 2095: 2094: 2092: 2090: 2075: 2069: 2068: 2058: 2021: 2015: 2014: 2004: 1968: 1962: 1961: 1951: 1919: 1913: 1912: 1911: 1905: 1895: 1855: 1849: 1848: 1838: 1806: 1800: 1799: 1789: 1757: 1751: 1750: 1740: 1707: 1701: 1700: 1690: 1657: 1651: 1650: 1640: 1604: 1598: 1597: 1596: 1590: 1580: 1544: 1538: 1537: 1535: 1533: 1517: 1511: 1510: 1508: 1506: 1491: 1485: 1484: 1482: 1480: 1465: 1459: 1458: 1456: 1454: 1438: 1432: 1431: 1400: 1394: 1393: 1391: 1389: 1374: 1368: 1367: 1365: 1363: 1344: 1338: 1337: 1335: 1333: 1318: 1312: 1311: 1309: 1307: 1292: 1286: 1285: 1283: 1281: 1270:www.sanger.ac.uk 1261: 1255: 1254: 1252: 1250: 1235: 1229: 1228: 1218: 1194: 1188: 1187: 1177: 1142: 1136: 1135: 1133: 1131: 1112: 856:, among others. 818:Michael Stratton 800:Academic faculty 514:Human Cell Atlas 442:, a database of 342: 339: 333: 321: 320: 313: 206:Frederick Sanger 152: 149: 147: 136: 135: 133: 132: 131: 126: 122: 119: 118: 117: 114: 31: 24: 20: 4641: 4640: 4636: 4635: 4634: 4632: 4631: 4630: 4586: 4585: 4584: 4579: 4563: 4531:Sir Henry Dale 4505: 4436:Dominic Cadbury 4431:William Castell 4414: 4397:Bridget Ogilvie 4379: 4343:Stephen Caddick 4324: 4275: 4145: 4132: 4111: 4039: 4034: 4004: 3999: 3967: 3921: 3855: 3797: 3778:Student Council 3730: 3629:Broad Institute 3617: 3595: 3534: 3419: 3414: 3374: 3371: 3366: 3365: 3355: 3353: 3344: 3343: 3339: 3286: 3282: 3272: 3270: 3266: 3255: 3249: 3245: 3235: 3233: 3220: 3219: 3215: 3205: 3203: 3188: 3184: 3136: 3132: 3087: 3083: 3073: 3071: 3062: 3061: 3057: 3020: 3016: 2971: 2967: 2922: 2918: 2905: 2904: 2900: 2890: 2888: 2879: 2878: 2874: 2864: 2862: 2857:. Nobel Prize. 2853: 2852: 2848: 2837: 2833: 2823: 2821: 2812: 2811: 2807: 2791:10.1038/464992a 2768: 2764: 2754: 2716:(9): e1000941. 2692: 2688: 2675: 2674: 2670: 2657: 2656: 2652: 2639: 2638: 2634: 2624: 2622: 2609: 2608: 2604: 2595: 2594: 2590: 2577: 2576: 2572: 2562: 2560: 2551: 2550: 2546: 2536: 2534: 2521: 2520: 2516: 2506: 2504: 2491: 2490: 2486: 2476: 2474: 2465: 2464: 2457: 2451:Wayback Machine 2442: 2438: 2428: 2426: 2413: 2412: 2408: 2350: 2344: 2340: 2335: 2331: 2321: 2319: 2310: 2309: 2305: 2295: 2293: 2284: 2283: 2279: 2269: 2267: 2266:on 27 June 2010 2258: 2257: 2253: 2214:Genome Medicine 2206: 2202: 2192: 2179: 2178: 2128: 2124: 2114: 2112: 2111:on 26 June 2010 2103: 2102: 2098: 2088: 2086: 2077: 2076: 2072: 2022: 2018: 1969: 1965: 1920: 1916: 1906: 1856: 1852: 1807: 1803: 1758: 1754: 1708: 1704: 1658: 1654: 1605: 1601: 1591: 1549:Stratton, M. R. 1545: 1541: 1531: 1529: 1518: 1514: 1504: 1502: 1493: 1492: 1488: 1478: 1476: 1467: 1466: 1462: 1452: 1450: 1441:Sulston, John. 1439: 1435: 1420:10.1038/455016a 1414:(7209): 16–21. 1401: 1397: 1387: 1385: 1376: 1375: 1371: 1361: 1359: 1346: 1345: 1341: 1331: 1329: 1320: 1319: 1315: 1305: 1303: 1294: 1293: 1289: 1279: 1277: 1262: 1258: 1248: 1246: 1237: 1236: 1232: 1195: 1191: 1175:10.1038/505027a 1143: 1139: 1129: 1127: 1114: 1113: 1109: 1104: 1089:Matrix Chambers 1081: 1029: 1009:startup company 974:John E. Sulston 971: 950: 945: 917:, Professor at 894: 882:David J. Lipman 874:David Altshuler 862: 822:Sarah Teichmann 802: 786: 777: 764: 713: 708: 616: 603: 570: 522: 509: 496: 479: 474: 436:family database 402: 343: 337: 334: 331: 322: 318: 311: 283: 243: 238: 144: 129: 127: 123: 120: 115: 112: 110: 108: 107: 99: 89: 17: 12: 11: 5: 4639: 4629: 4628: 4626:Wellcome Trust 4623: 4618: 4613: 4608: 4603: 4598: 4581: 4580: 4568: 4565: 4564: 4562: 4561: 4558: 4553: 4550: 4547: 4542: 4535: 4529: 4526: 4523: 4520: 4517: 4516:Capital Awards 4513: 4511: 4507: 4506: 4504: 4503: 4501:Henry Wellcome 4498: 4493: 4488: 4483: 4478: 4473: 4468: 4463: 4458: 4453: 4448: 4443: 4438: 4433: 4428: 4422: 4420: 4416: 4415: 4413: 4412: 4406: 4403:Michael Dexter 4400: 4394: 4391:Peter Williams 4387: 4385: 4381: 4380: 4378: 4377: 4374: 4371: 4368: 4365: 4362: 4359: 4356: 4355:Mark Henderson 4353: 4350: 4347: 4344: 4341: 4338: 4332: 4330: 4326: 4325: 4323: 4322: 4317: 4312: 4310:Bryan Grenfell 4307: 4302: 4299: 4294: 4289: 4283: 4281: 4277: 4276: 4274: 4273: 4268: 4263: 4258: 4253: 4248: 4243: 4238: 4233: 4228: 4223: 4218: 4213: 4208: 4201: 4196: 4191: 4186: 4181: 4176: 4171: 4166: 4159: 4153: 4151: 4147: 4146: 4139: 4137: 4134: 4133: 4131: 4130: 4125: 4119: 4117: 4113: 4112: 4110: 4109: 4104: 4099: 4094: 4091: 4088: 4083: 4078: 4073: 4068: 4065: 4060: 4054: 4052: 4045: 4041: 4040: 4037:Wellcome Trust 4033: 4032: 4025: 4018: 4010: 4001: 4000: 3998: 3997: 3985: 3972: 3969: 3968: 3966: 3965: 3960: 3955: 3950: 3945: 3940: 3935: 3929: 3927: 3926:Related topics 3923: 3922: 3920: 3919: 3914: 3909: 3904: 3899: 3894: 3889: 3884: 3879: 3874: 3869: 3863: 3861: 3857: 3856: 3854: 3853: 3847: 3841: 3836: 3830: 3824: 3818: 3812: 3805: 3803: 3799: 3798: 3796: 3795: 3789: 3783: 3782: 3781: 3769: 3763: 3757: 3751: 3745: 3738: 3736: 3732: 3731: 3729: 3728: 3723: 3718: 3712: 3707: 3701: 3695: 3690: 3684: 3678: 3672: 3667: 3661: 3655: 3649: 3643: 3637: 3631: 3625: 3623: 3619: 3618: 3616: 3615: 3610: 3603: 3601: 3597: 3596: 3594: 3593: 3588: 3583: 3578: 3573: 3568: 3563: 3558: 3553: 3548: 3542: 3540: 3536: 3535: 3533: 3532: 3490: 3464: 3446: 3427: 3425: 3421: 3420: 3417:Bioinformatics 3413: 3412: 3405: 3398: 3390: 3384: 3383: 3370: 3369:External links 3367: 3364: 3363: 3337: 3280: 3243: 3213: 3182: 3130: 3081: 3055: 3014: 2965: 2916: 2898: 2872: 2846: 2831: 2805: 2762: 2686: 2668: 2650: 2632: 2602: 2588: 2570: 2544: 2527:Science Museum 2514: 2484: 2455: 2436: 2406: 2338: 2329: 2303: 2277: 2251: 2200: 2122: 2096: 2070: 2016: 1963: 1914: 1850: 1801: 1752: 1702: 1663:"Ensembl 2015" 1652: 1599: 1539: 1512: 1486: 1460: 1433: 1395: 1369: 1339: 1313: 1302:on 7 July 2010 1287: 1256: 1230: 1189: 1137: 1106: 1105: 1103: 1100: 1080: 1077: 1028: 1025: 991:Sydney Brenner 987:Robert Horvitz 970: 967: 958:Wellcome Trust 949: 946: 944: 943: 940:Richard Durbin 937: 932: 927: 921: 912: 898: 893: 890: 870:advisory board 861: 858: 826:Matthew Hurles 814:Nicole Soranzo 801: 798: 790:Matthew_Hurles 785: 782: 776: 773: 763: 760: 712: 709: 707: 706: 703: 697: 670: 667: 660: 655: 650: 645: 640: 630: 624: 615: 614:Collaborations 612: 602: 599: 569: 566: 526:human genetics 521: 518: 508: 505: 495: 492: 478: 475: 473: 472: 462: 454:model organism 447: 437: 427: 424:protein family 417: 406: 401: 400: 394: 388: 381: 375: 365: 354: 345: 344: 325: 323: 316: 310: 307: 282: 279: 263:Cambridgeshire 242: 239: 237: 234: 232:Tree of Life. 210:DNA sequencing 203:Nobel laureate 184:Wellcome Trust 154: 153: 142: 138: 137: 105: 101: 100: 97:United Kingdom 93:Cambridgeshire 91: 85: 83: 79: 78: 73: 69: 68: 65: 61: 60: 57: 51: 50: 48:Matthew Hurles 45: 41: 40: 37: 33: 32: 15: 9: 6: 4: 3: 2: 4638: 4627: 4624: 4622: 4619: 4617: 4614: 4612: 4609: 4607: 4604: 4602: 4599: 4597: 4594: 4593: 4591: 4578: 4577: 4566: 4559: 4557: 4554: 4551: 4548: 4546: 4543: 4540: 4536: 4534: 4530: 4527: 4524: 4521: 4518: 4515: 4514: 4512: 4508: 4502: 4499: 4497: 4494: 4492: 4489: 4487: 4484: 4482: 4479: 4477: 4474: 4472: 4469: 4467: 4466:Richard Hynes 4464: 4462: 4459: 4457: 4454: 4452: 4451:Oliver Franks 4449: 4447: 4444: 4442: 4439: 4437: 4434: 4432: 4429: 4427: 4426:Damon Buffini 4424: 4423: 4421: 4417: 4410: 4407: 4404: 4401: 4398: 4395: 4392: 4389: 4388: 4386: 4382: 4375: 4372: 4369: 4366: 4363: 4360: 4357: 4354: 4351: 4348: 4346:Simon Chaplin 4345: 4342: 4339: 4337: 4336:Jeremy Farrar 4334: 4333: 4331: 4327: 4321: 4318: 4316: 4315:Naguib Kheraj 4313: 4311: 4308: 4306: 4305:William Burns 4303: 4300: 4298: 4295: 4293: 4290: 4288: 4285: 4284: 4282: 4278: 4272: 4269: 4267: 4264: 4262: 4259: 4257: 4254: 4252: 4249: 4247: 4244: 4242: 4239: 4237: 4234: 4232: 4229: 4227: 4224: 4222: 4219: 4217: 4214: 4212: 4209: 4207: 4206: 4202: 4200: 4197: 4195: 4192: 4190: 4187: 4185: 4182: 4180: 4177: 4175: 4172: 4170: 4167: 4165: 4164: 4160: 4158: 4155: 4154: 4152: 4148: 4143: 4129: 4126: 4124: 4121: 4120: 4118: 4114: 4108: 4105: 4103: 4100: 4098: 4095: 4092: 4089: 4087: 4084: 4082: 4079: 4077: 4074: 4072: 4069: 4066: 4064: 4061: 4059: 4056: 4055: 4053: 4049: 4046: 4042: 4038: 4031: 4026: 4024: 4019: 4017: 4012: 4011: 4008: 3996: 3995: 3986: 3984: 3983: 3974: 3973: 3970: 3964: 3961: 3959: 3956: 3954: 3951: 3949: 3946: 3944: 3941: 3939: 3936: 3934: 3931: 3930: 3928: 3924: 3918: 3915: 3913: 3910: 3908: 3905: 3903: 3900: 3898: 3895: 3893: 3892:Pileup format 3890: 3888: 3885: 3883: 3880: 3878: 3875: 3873: 3870: 3868: 3865: 3864: 3862: 3858: 3851: 3848: 3845: 3842: 3840: 3837: 3834: 3831: 3828: 3825: 3822: 3819: 3816: 3813: 3810: 3807: 3806: 3804: 3800: 3793: 3790: 3787: 3784: 3779: 3776: 3775: 3773: 3770: 3767: 3764: 3761: 3758: 3755: 3752: 3749: 3746: 3743: 3740: 3739: 3737: 3735:Organizations 3733: 3727: 3724: 3722: 3719: 3716: 3713: 3711: 3708: 3705: 3702: 3699: 3696: 3694: 3691: 3688: 3685: 3682: 3679: 3676: 3673: 3671: 3668: 3665: 3662: 3659: 3656: 3653: 3650: 3647: 3644: 3641: 3638: 3635: 3632: 3630: 3627: 3626: 3624: 3620: 3614: 3611: 3609: 3605: 3604: 3602: 3598: 3592: 3589: 3587: 3584: 3582: 3579: 3577: 3574: 3572: 3569: 3567: 3564: 3562: 3559: 3557: 3554: 3552: 3549: 3547: 3544: 3543: 3541: 3537: 3531: 3527: 3523: 3519: 3515: 3511: 3507: 3503: 3499: 3495: 3491: 3489: 3488:Gene Ontology 3485: 3481: 3477: 3473: 3469: 3465: 3463: 3459: 3455: 3451: 3447: 3445: 3441: 3437: 3433: 3429: 3428: 3426: 3422: 3418: 3411: 3406: 3404: 3399: 3397: 3392: 3391: 3388: 3381: 3373: 3372: 3351: 3347: 3341: 3333: 3329: 3325: 3321: 3316: 3311: 3307: 3303: 3299: 3295: 3291: 3284: 3265: 3261: 3254: 3247: 3231: 3227: 3223: 3217: 3201: 3197: 3193: 3186: 3178: 3174: 3170: 3166: 3161: 3156: 3153:(5618): 409. 3152: 3148: 3144: 3140: 3134: 3126: 3122: 3117: 3112: 3108: 3104: 3100: 3096: 3092: 3085: 3069: 3065: 3059: 3051: 3047: 3042: 3037: 3034:(6784): 264. 3033: 3029: 3025: 3018: 3010: 3006: 3001: 2996: 2992: 2988: 2985:(6857): 660. 2984: 2980: 2976: 2969: 2961: 2957: 2953: 2949: 2944: 2939: 2936:(6785): 389. 2935: 2931: 2927: 2920: 2912: 2908: 2902: 2886: 2882: 2876: 2860: 2856: 2850: 2842: 2835: 2819: 2815: 2809: 2801: 2797: 2792: 2787: 2784:(7291): 992. 2783: 2779: 2778: 2773: 2766: 2758: 2751: 2747: 2742: 2737: 2732: 2727: 2723: 2719: 2715: 2711: 2710: 2705: 2701: 2697: 2690: 2682: 2678: 2672: 2664: 2660: 2654: 2646: 2642: 2636: 2620: 2616: 2612: 2606: 2598: 2592: 2584: 2580: 2574: 2558: 2554: 2548: 2532: 2528: 2524: 2518: 2502: 2498: 2494: 2488: 2472: 2468: 2462: 2460: 2452: 2448: 2445: 2440: 2424: 2420: 2416: 2410: 2402: 2398: 2394: 2390: 2385: 2384:2027.42/62838 2380: 2376: 2372: 2368: 2364: 2360: 2356: 2349: 2342: 2333: 2317: 2313: 2307: 2291: 2287: 2281: 2265: 2261: 2255: 2247: 2243: 2238: 2233: 2228: 2227:10.1186/gm504 2223: 2219: 2215: 2211: 2204: 2196: 2189: 2183: 2175: 2171: 2166: 2161: 2157: 2153: 2150:(9): 1100–4. 2149: 2145: 2141: 2137: 2133: 2126: 2110: 2106: 2100: 2084: 2080: 2074: 2066: 2062: 2057: 2052: 2048: 2044: 2040: 2036: 2032: 2030: 2020: 2012: 2008: 2003: 1998: 1994: 1990: 1986: 1982: 1978: 1976: 1967: 1959: 1955: 1950: 1945: 1941: 1937: 1933: 1929: 1925: 1918: 1910: 1903: 1899: 1894: 1889: 1885: 1881: 1877: 1873: 1869: 1865: 1861: 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D.; 1854: 1846: 1842: 1837: 1832: 1828: 1824: 1820: 1816: 1812: 1805: 1797: 1793: 1788: 1783: 1779: 1775: 1771: 1767: 1763: 1756: 1748: 1744: 1739: 1734: 1730: 1726: 1722: 1718: 1714: 1706: 1698: 1694: 1689: 1684: 1680: 1676: 1672: 1668: 1664: 1656: 1648: 1644: 1639: 1634: 1630: 1626: 1622: 1618: 1614: 1610: 1603: 1595: 1588: 1584: 1579: 1574: 1570: 1566: 1562: 1558: 1554: 1550: 1543: 1527: 1523: 1516: 1500: 1496: 1490: 1474: 1470: 1464: 1448: 1444: 1437: 1429: 1425: 1421: 1417: 1413: 1409: 1405: 1399: 1383: 1379: 1373: 1357: 1353: 1349: 1343: 1327: 1323: 1317: 1301: 1297: 1291: 1275: 1271: 1267: 1260: 1244: 1240: 1234: 1226: 1222: 1217: 1212: 1208: 1204: 1200: 1193: 1185: 1181: 1176: 1171: 1167: 1163: 1159: 1155: 1151: 1147: 1141: 1125: 1121: 1117: 1111: 1107: 1099: 1097: 1092: 1090: 1086: 1076: 1074: 1070: 1066: 1062: 1058: 1054: 1050: 1046: 1042: 1038: 1034: 1024: 1022: 1018: 1014: 1013:Mike Stratton 1010: 1005: 1003: 999: 998:Allan Bradley 994: 992: 988: 984: 980: 975: 963: 960:and the UK's 959: 954: 941: 938: 936: 933: 931: 930:Julian Rayner 928: 925: 922: 920: 916: 913: 911: 907: 903: 900: 899: 897: 889: 887: 883: 879: 875: 871: 867: 857: 855: 851: 847: 843: 839: 838:Chris Ponting 835: 831: 827: 823: 819: 815: 811: 807: 797: 795: 791: 781: 772: 770: 759: 757: 753: 749: 744: 742: 738: 734: 728: 726: 717: 704: 702: 698: 695: 691: 687: 686: 681: 680: 675: 671: 668: 665: 661: 659: 656: 654: 651: 649: 646: 644: 641: 638: 634: 631: 629: 626: 625: 623: 621: 611: 609: 598: 595: 591: 587: 583: 579: 575: 565: 561: 559: 555: 551: 547: 543: 539: 535: 531: 527: 517: 515: 504: 502: 491: 483: 470: 466: 463: 460: 459: 455: 451: 448: 445: 441: 438: 435: 431: 428: 425: 421: 418: 415: 411: 408: 407: 405: 398: 395: 392: 389: 386: 382: 379: 376: 373: 369: 366: 363: 359: 356: 355: 353: 351: 350:Bioinformatic 341: 329: 324: 315: 314: 306: 304: 300: 296: 293: 288: 278: 276: 272: 268: 264: 255: 247: 233: 229: 227: 226:collaboration 223: 219: 215: 211: 207: 204: 200: 196: 192: 187: 185: 181: 177: 173: 169: 165: 161: 151: 143: 139: 134: 106: 102: 98: 94: 88: 84: 80: 77: 74: 70: 66: 62: 58: 56: 52: 49: 46: 42: 38: 34: 30: 25: 19: 4574: 4539:Postdoctoral 4496:John Sulston 4491:David Stuart 4471:Anne Johnson 4409:Mark Walport 4373:James Thomas 4320:Fiona Powrie 4203: 4161: 4106: 3992: 3980: 3887:Nexus format 3882:NeXML format 3877:FASTQ format 3872:FASTA format 3860:File formats 3720: 3622:Institutions 3354:. 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Index


Matthew Hurles
Faculty
Wellcome Genome Campus
Hinxton
Cambridgeshire
United Kingdom
52°04′39″N 00°11′15″E / 52.07750°N 0.18750°E / 52.07750; 0.18750
sanger.ac.uk
non-profit
genomics
genetics
Wellcome Trust
Hinxton
Cambridge
European Bioinformatics Institute
Nobel laureate
Frederick Sanger
DNA sequencing
Human Genome Project
human genome
data sharing
collaboration


Cambridgeshire
European Bioinformatics Institute
data centre
John Sulston
DNA

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