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Anorectic

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with an approximately equal amount for situations, in which fatigue was not deemed to be an acceptable option. Following the war, large amphetamine surpluses were redirected for use on the black and the civilian market. Indeed, amphetamine itself was sold commercially as an appetite suppressant until
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approach. Drinking water prior to each meal may help in appetite suppression. Consumption of 500 mL (18 imp fl oz; 17 US fl oz) of water 30 minutes before meals has been correlated with modest weight loss (1–2 kg; 2.2–4.4 lb) in obese men and women over a
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Mohammadpour, Saba; Amini, Mohammad Reza; Shahinfar, Hossein; Tijani, Aliyu Jibril; Shahavandi, Mahshid; Ghorbaninejad, Parivash; Djafarian, Kurosh; Shab-Bidar, Sakineh (September 2020). "Effects of glucomannan supplementation on weight loss in overweight and obese adults: A systematic review and
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Doig, GS; Simpson, F; Heighes; Bellomo, R; Chesher, D; Caterson, ID; Reade, MC; Harrigan, PWJ (2015-12-01). "Restricted versus continued standard caloric intake during the management of refeeding syndrome in critically ill adults: a randomised, parallel-group, multicentre, single-blind controlled
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resulted in an FDA ban on its inclusion in dietary supplements in 2004. A Federal judge later overturned this ban in 2005 during a challenge by supplement maker Nutraceuticals. It is also debatable as to whether the ephedrine ban had more to do with its use as a
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Abenhaim, Lucien; Moride, Yola; Brenot, François; Rich, Stuart; Benichou, Jacques; Kurz, Xavier; Higenbottam, Tim; Oakley, Celia; Wouters, Emil; Aubier, Michel; Simonneau, Gérald; Bégaud, Bernard (1996).
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Guo, Liping; Yokoyama, Wallace; Chen, Maoshen; Zhong, Fang (November 2021). "Konjac glucomannan molecular and rheological properties that delay gastric emptying and improve the regulation of appetite".
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Wood, Douglas M; Emmett-Oglesby, Michael W (1988). "Substitution and cross-tolerance profiles of anorectic drugs in rats trained to detect the discriminative stimulus properties of cocaine".
58:, eating disorders, and related health concerns. The anorexiant effect can be induced through diverse mechanisms, ranging from hormonal regulation to neural signaling. 1225: 316:, or metabolically stressed because of severe illness. When too much food or liquid nutrition supplement is eaten during the initial four to seven days following a 159:. Several appetite suppressants are based on a mix of natural ingredients, mostly using green tea as its basis, in combination with other plant extracts such as 374: 54:
to create a feeling of fullness or reduce the desire to eat. The understanding of anorexiant effects is crucial in the development of interventions for
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it was outlawed in most parts of the world in the late 1950s because of safety issues. Many amphetamines produce side effects, including
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may cause neurologic, pulmonary, cardiac, neuromuscular, and hematologic symptoms—many of which, if severe enough, may result in death.
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damage associated with pharmaceutical anorectic agents have led to the withdrawal of products from the market. This was the case with
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Refeeding syndrome can occur when someone does not eat for several days at a time usually beginning after 4–5 days with no food.
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Dennis, Elizabeth A.; Dengo, Ana Laura; Comber, Dana L.; Flack, Kyle D.; Savla, Jyoti; Davy, Kevin P.; Davy, Brenda M. (2009).
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who begin to reintroduce normal eating habits after a period of malnutrition may be at increased risk for refeeding syndrome.
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Schubert, Matthew M.; Irwin, Christopher; Seay, Rebekah F.; Clarke, Holly E.; Allegro, Deanne; Desbrow, Ben (December 2017).
679: 1010:"Effect of excessive water intake on body weight, body mass index, body fat, and appetite of overweight female participants" 1285: 670:
Lemke, Thomas L.; Williams, David A., eds. (2012). "Anorexiants as Pharmacologic Agents in the Management of Obesity".
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hydrochloride – USFDA-approved for the treatment of obesity (as a short-term) under the brand name "Desoxyn".
531: 516: 258:(FDA) to request its withdrawal from the market in the United States in 2000, and similar concerns regarding 431:(one of the two components of Fen-phen. Since discontinued to its potential for causing valvulopathies and 545: 279: 255: 2184: 199: 1673: 583:- US FDA approved for the treatment of binge-eating disorder in adults under the brand name "Vyvanse". 462:(in some countries withdrawn from the market because of concerns regarding its cardiovascular effects) 2188: 1533:"The role of leptin and ghrelin in the regulation of food intake and body weight in humans: a review" 1226:"FDA requests the withdrawal of the weight-loss drug Belviq, Belviq XR (lorcaserin) from the market" 2280: 2251: 2051: 1665: 1242: 472: 2445: 2291: 1729: 1310: 1260:"European Medicines Agency recommends withdrawal of benfluorex from the market in European Union" 651: 308:
disturbance which occurs as a result of reinstitution of nutrition in people and animals who are
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are among the hormones involved in appetite control. Additionally, neurotransmitters such as
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in the central nervous system contribute significantly to the regulation of food intake.
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The following drugs are listed as "centrally-acting antiobesity preparations" in the
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Webb GJ, Smith K, Thursby-Pelham F, Smith T, Stroud MA, Da Silva AN (2011).
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is known to hamper appetite. Amphetamine-Dextroamphetamine is used to treat
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Heal, David J; Smith, Sharon L; Gosden, Jane; Nutt, David J (June 2013).
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Numerous pharmaceutical compounds are marketed as appetite suppressants.
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manufacture rather than health concerns with the ingredient as such.
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Other compounds with known appetite suppressant activity include:
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Handbook of Non Drug Intervention (HANDI) Project Team (2013).
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have been subject to some scientific research as a potential
246:). Likewise, association of the related appetite suppressant 112: 92: 1531:
Klok, M. D.; Jakobsdottir, S.; Drent, M. L. (January 2007).
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and is usually under the trade name "Adderall" or "Mydayis".
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The German and Finnish militaries issued amphetamines (
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Anatomical Therapeutic Chemical Classification System
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By contrast, an appetite stimulant is referred to as
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International Journal of Food Sciences and Nutrition
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The following are listed as appetite depressants by
1452: 787: 708:"The Nazi Death Machine: Hitler's Drugged Soldiers" 274: 1404:"Caffeine, coffee, and appetite control: a review" 1358: 889:"Aminorex to Fen/Phen : An Epidemic Foretold" 475:, an index of medical journal articles and books. 42:, resulting in lower food consumption, leading to 2476: 1460:meta-analysis of randomized controlled trials". 1014:Journal of Natural Science, Biology and Medicine 155:, some appetite suppressants are also available 536:Attention deficit hyperactivity disorder (ADHD) 215:, making prolonged unsupervised use dangerous. 151:Used on a short-term basis clinically to treat 1059:Mehanna HM, Moledina J, Travis J (June 2008). 1714: 1008:Vij, Vinu Ashokkumar; Joshi, Anjalis (2014). 669: 1052: 930:"Pre-meal water consumption for weight loss" 1674:"Anorexiant Agents: Considerations for Use" 699: 1721: 1707: 1606:United States Food and Drug Administration 733:"Benzedrine Sulphate in Clinical Medicine" 235:in the 1960s, and again in the 1990s with 19:For the common meaning of "anorexic", see 1664:at the U.S. National Library of Medicine 1548: 1427: 1230:Center for Drug Evaluation and Researcher 1169: 1084: 1035: 1025: 984: 904: 863: 821: 764: 218: 46:. These substances work by affecting the 1671: 1007: 688: 1685:University of Washington Medical Center 1591: 1585:Center for Drug Evaluation and Research 1201:University Hospitals Bristol and Weston 886: 194:was supplied with more than 72 million 2477: 1327: 705: 1702: 544:sulfate (also known as amfetamine) – 365: 290: 730: 663: 131:), and such drugs are also known as 13: 1101: 921: 186:) to soldiers commonly during the 14: 2496: 1655: 1599:"Desoxyn Prescribing Information" 1550:10.1111/j.1467-789X.2006.00270.x 1335:"Evekeo Prescribing Information" 275:Non-pharmacological alternatives 1672:Mitchell, Kari (January 1997). 1620: 1573: 1524: 1395: 1352: 1303: 1278: 1252: 1236: 1218: 1207: 1186: 1145: 1111:The Lancet Respiratory Medicine 1001: 852:New England Journal of Medicine 706:Ulrich, Andreas (May 6, 2005). 548:-approved for the treatment of 952: 880: 838: 781: 724: 552:under the brand name "Evekeo". 384:(also known as diethylpropion) 163:, found naturally in seaweed. 1: 1510:10.1016/j.foodhyd.2021.106894 1420:10.1080/09637486.2017.1320537 1123:10.1016/S2213-2600(15)00418-X 794:Journal of Psychopharmacology 657: 532:Amphetamine-Dextroamphetamine 517:Pyroglutamyl-histidyl-glycine 167:of this class are frequently 737:Postgraduate Medical Journal 606:(brand name Ozempic/Wegovy) 280:Weight loss effects of water 256:Food and Drug Administration 118: 98: 7: 1474:10.1016/j.obmed.2020.100276 934:Australian Family Physician 865:10.1056/NEJM199608293350901 645: 16:Drug which reduces appetite 10: 2501: 731:Bett, W. R. (1946-08-01). 672:Foye's Medicinal Chemistry 294: 146: 113: 93: 18: 2435: 2369: 2351: 2315: 2290: 2267: 2175: 2125: 1995: 1937: 1754: 1745: 1264:European Medicines Agency 320:event, the production of 287:period of 8 to 12 weeks. 1666:Medical Subject Headings 1027:10.4103/0976-9668.136180 806:10.1177/0269881113482532 38:is a drug which reduces 1587:. FDA. August 28, 2023. 906:10.1161/01.cir.99.1.156 887:Fishman, A. P. (1999). 749:10.1136/pgmj.22.250.205 652:Anti-obesity medication 332:in cells may cause low 25:Anti-obesity medication 433:pulmonary hypertension 225:pulmonary hypertension 219:Public health concerns 88:The term is (from the 48:central nervous system 2316:Absorption inhibitors 1203:. Clinical Guideline. 600:as brand name Saxenda 350:electrolyte imbalance 1194:"Refeeding Syndrome" 977:10.1038/oby.2009.235 141:appetite suppressant 2088:Phenylpropanolamine 1967:Levopropylhexedrine 1939:Adrenergic agonists 1769:4-Methylamphetamine 1681:Drug Therapy Topics 1266:. December 12, 2009 1243:MeSH list of agents 512:Phenylpropanolamine 284:non-pharmacological 248:phenylpropanolamine 223:Epidemics of fatal 175:family, related to 2462:Never to phase III 2387:Desiccated thyroid 2033:Dexmethylphenidate 1730:Antiobesity agents 1632:The Times of India 1498:Food Hydrocolloids 1373:10.1007/BF00181948 1361:Psychopharmacology 1232:. FDA. 2020-02-13. 1171:10.52964/AMJA.0470 366:List of anorectics 336:concentrations of 302:Refeeding syndrome 297:Refeeding syndrome 291:Refeeding syndrome 2472: 2471: 2361:2,4-Dinitrophenol 2294:receptor agonists 2189:glucagon agonists 2121: 2120: 1839:Dimethylcathinone 1834:Dextroamphetamine 681:978-1-60913-345-0 581:Lisdexamphetamine 550:exogenous obesity 413: 358:Individuals with 190:. Similarly, the 56:weight management 52:neurotransmitters 2492: 1889:Lisdexamfetamine 1814:Chlorphentermine 1752: 1751: 1723: 1716: 1709: 1700: 1699: 1695: 1693: 1691: 1678: 1650: 1649: 1647: 1646: 1624: 1618: 1617: 1615: 1613: 1603: 1595: 1589: 1588: 1577: 1571: 1570: 1552: 1528: 1522: 1521: 1492: 1486: 1485: 1462:Obesity Medicine 1456: 1450: 1449: 1431: 1399: 1393: 1392: 1356: 1350: 1349: 1347: 1345: 1339: 1331: 1325: 1324: 1322: 1321: 1307: 1301: 1300: 1298: 1297: 1282: 1276: 1275: 1273: 1271: 1256: 1250: 1240: 1234: 1233: 1222: 1216: 1211: 1205: 1204: 1198: 1190: 1184: 1183: 1173: 1149: 1143: 1142: 1105: 1099: 1098: 1088: 1077:10.1136/bmj.a301 1071:(7659): 1495–8. 1056: 1050: 1049: 1039: 1029: 1005: 999: 998: 988: 956: 950: 949: 925: 919: 918: 908: 884: 878: 877: 867: 842: 836: 835: 825: 785: 779: 778: 768: 728: 722: 721: 719: 718: 703: 697: 692: 686: 685: 667: 625:such as heroin, 411: 198:tablets and the 188:Second World War 157:over-the-counter 130: 127: 124: 121: 116: 115: 110: 107: 104: 101: 96: 95: 21:Anorexia nervosa 2500: 2499: 2495: 2494: 2493: 2491: 2490: 2489: 2475: 2474: 2473: 2468: 2467: 2452:Clinical trials 2431: 2365: 2347: 2311: 2293: 2286: 2263: 2187: 2171: 2128: 2117: 2098:Propylhexedrine 2073:Phendimetrazine 2068:Methylphenidate 2028:Dexfenfluramine 1991: 1933: 1904:Norfenfluramine 1899:Methamphetamine 1761:phenethylamines 1759: 1741: 1727: 1689: 1687: 1676: 1658: 1653: 1644: 1642: 1626: 1625: 1621: 1611: 1609: 1608:. December 2013 1601: 1597: 1596: 1592: 1579: 1578: 1574: 1537:Obesity Reviews 1529: 1525: 1493: 1489: 1457: 1453: 1400: 1396: 1357: 1353: 1343: 1341: 1337: 1333: 1332: 1328: 1319: 1317: 1309: 1308: 1304: 1295: 1293: 1284: 1283: 1279: 1269: 1267: 1258: 1257: 1253: 1241: 1237: 1224: 1223: 1219: 1212: 1208: 1196: 1192: 1191: 1187: 1150: 1146: 1117:(12): 943–952. 1106: 1102: 1057: 1053: 1006: 1002: 957: 953: 926: 922: 885: 881: 843: 839: 786: 782: 729: 725: 716: 714: 704: 700: 693: 689: 682: 668: 664: 660: 648: 587:Methamphetamine 556:Methylphenidate 408:Dexfenfluramine 368: 299: 293: 277: 269:methamphetamine 254:stroke led the 221: 149: 128: 125: 122: 108: 105: 102: 28: 17: 12: 11: 5: 2498: 2488: 2487: 2470: 2469: 2466: 2465: 2464: 2463: 2460: 2449: 2443: 2437: 2436: 2433: 2432: 2430: 2429: 2424: 2419: 2414: 2409: 2404: 2399: 2394: 2389: 2384: 2379: 2373: 2371: 2367: 2366: 2364: 2363: 2357: 2355: 2349: 2348: 2346: 2345: 2340: 2335: 2330: 2325: 2319: 2317: 2313: 2312: 2310: 2309: 2304: 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2239: 2238:Oxyntomodulin 2236: 2234: 2231: 2229: 2226: 2223: 2220: 2218: 2215: 2213: 2210: 2208: 2205: 2203: 2200: 2198: 2195: 2194: 2192: 2190: 2186: 2182: 2178: 2174: 2168: 2165: 2163: 2160: 2158: 2155: 2153: 2150: 2148: 2145: 2143: 2140: 2138: 2135: 2134: 2132: 2130: 2124: 2114: 2111: 2109: 2106: 2104: 2101: 2099: 2096: 2094: 2091: 2089: 2086: 2084: 2083:Phenmetrazine 2081: 2079: 2076: 2074: 2071: 2069: 2066: 2064: 2061: 2059: 2056: 2053: 2049: 2046: 2044: 2041: 2039: 2036: 2034: 2031: 2029: 2026: 2023: 2019: 2016: 2014: 2011: 2009: 2006: 2004: 2001: 2000: 1998: 1994: 1987: 1983: 1980: 1978: 1975: 1973: 1970: 1968: 1965: 1963: 1960: 1958: 1955: 1953: 1950: 1948: 1945: 1944: 1942: 1940: 1936: 1930: 1927: 1925: 1924:Xylopropamine 1922: 1919: 1915: 1912: 1910: 1907: 1905: 1902: 1900: 1897: 1895: 1892: 1890: 1887: 1885: 1882: 1880: 1877: 1875: 1872: 1870: 1867: 1865: 1862: 1860: 1857: 1855: 1852: 1850: 1847: 1845: 1842: 1840: 1837: 1835: 1832: 1830: 1827: 1825: 1822: 1820: 1817: 1815: 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Index

Anorexia nervosa
Anti-obesity medication
appetite
weight loss
central nervous system
neurotransmitters
weight management
Ghrelin
leptin
peptide YY
serotonin
dopamine
orexigenic
Greek
obesity
over-the-counter
fucoxanthin
Drugs
stimulants
phenethylamine
amphetamine
Pervitin
Second World War
UK military
Benzedrine
US military
addiction
tachycardia
hypertension
pulmonary hypertension

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