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Causal model

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data alone, without the need for an experimental intervention, which might be expensive, lengthy or even unethical (e.g., asking subjects to take up smoking). The set of rules is complete (it can be used to derive every true statement in this system). An algorithm can determine whether, for a given model, a solution is computable in
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conclusions can be drawn from an incomplete dataset. In some cases, data from studies of multiple populations can be combined (via transportation) to allow conclusions about an unmeasured population. In some cases, combining estimates (e.g., P(W|X)) from multiple studies can increase the precision of a conclusion.
369:, but once it became a rote method, it lost its utility, leading some practitioners to reject any relationship to causality. Economists adopted the algebraic part of path analysis, calling it simultaneous equation modeling. However, economists still avoided attributing causal meaning to their equations. 4600:
For linear models, the indirect effect can be computed by taking the product of all the path coefficients along a mediated pathway. The total indirect effect is computed by the sum of the individual indirect effects. For linear models mediation is indicated when the coefficients of an equation fitted
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Counterfactuals can indicate the existence of a causal relationship. Models that can answer counterfactuals allow precise interventions whose consequences can be predicted. At the extreme, such models are accepted as physical laws (as in the laws of physics, e.g., inertia, which says that if force is
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The highest level, counterfactual, involves consideration of an alternate version of a past event, or what would happen under different circumstances for the same experimental unit. For example, what is the probability that, if a store had doubled the price of floss, the toothpaste-purchasing shopper
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introduced the "exchangeability" approach to handling confounding by considering a counterfactual. They proposed assessing what would have happened to the treatment group if they had not received the treatment and comparing that outcome to that of the control group. If they matched, confounding was
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Do-calculus provides a general criterion for transport: A target variable can be transformed into another expression via a series of do-operations that does not involve any "difference-producing" variables (those that distinguish the two populations). An analogous rule applies to studies that have
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Indirect effects cannot be "controlled" because the direct path cannot be disabled by holding another variable constant. The natural indirect effect (NIE) is the effect on gum health (Y) from flossing (M). The NIE is calculated as the sum of (floss and no-floss cases) of the difference between the
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If the backdoor criterion is satisfied for (X,Y), X and Y are deconfounded by the set of confounder variables. It is not necessary to control for any variables other than the confounders. The backdoor criterion is a sufficient but not necessary condition to find a set of variables Z to decounfound
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Any causal model can be implemented as a Bayesian network. Bayesian networks can be used to provide the inverse probability of an event (given an outcome, what are the probabilities of a specific cause). This requires preparation of a conditional probability table, showing all possible inputs and
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The do calculus is the set of manipulations that are available to transform one expression into another, with the general goal of transforming expressions that contain the do operator into expressions that do not. Expressions that do not include the do operator can be estimated from observational
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involves a three-level abstraction he calls the ladder of causation. The lowest level, Association (seeing/observing), entails the sensing of regularities or patterns in the input data, expressed as correlations. The middle level, Intervention (doing), predicts the effects of deliberate actions,
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For analysing the causal effect of X on Y in a causal model all confounder variables must be addressed (deconfounding). To identify the set of confounders, (1) every noncausal path between X and Y must be blocked by this set; (2) without disrupting any causal paths; and (3) without creating any
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A different conceptualization of causality involves the notion of invariant relationships. In the case of identifying handwritten digits, digit shape controls meaning, thus shape and meaning are the invariants. Changing the shape changes the meaning. Other properties do not (e.g., color). This
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Examining a counterfactual using a causal model involves three steps. The approach is valid regardless of the form of the model relationships, linear or otherwise. When the model relationships are fully specified, point values can be computed. In other cases (e.g., when only probabilities are
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Causal models are mathematical models representing causal relationships within an individual system or population. They facilitate inferences about causal relationships from statistical data. They can teach us a good deal about the epistemology of causation, and about the relationship between
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This level asserts specific causal relationships between events. Causality is assessed by experimentally performing some action that affects one of the events. Example: after doubling the price of toothpaste, what would be the new probability of purchasing? Causality cannot be established by
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Where two models match on all relevant variables and data from one model is known to be unbiased, data from one population can be used to draw conclusions about the other. In other cases, where data is known to be biased, reweighting can allow the dataset to be transported. In a third case,
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Queries are questions asked based on a specific model. They are generally answered via performing experiments (interventions). Interventions take the form of fixing the value of one variable in a model and observing the result. Mathematically, such queries take the form (from the example):
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The rules do not imply that any query can have its do operators removed. In those cases, it may be possible to substitute a variable that is subject to manipulation (e.g., diet) in place of one that is not (e.g., blood cholesterol), which can then be transformed to remove the do. Example:
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An essential element of correlational study design is to identify potentially confounding influences on the variable under study, such as demographics. These variables are controlled for to eliminate those influences. However, the correct list of confounding variables cannot be determined
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invariance should carry across datasets generated in different contexts (the non-invariant properties form the context). Rather than learning (assessing causality) using pooled data sets, learning on one and testing on another can help distinguish variant from invariant properties.
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Independence conditions are rules for deciding whether two variables are independent of each other. Variables are independent if the values of one do not directly affect the values of the other. Multiple causal models can share independence conditions. For example, the models
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Causal models provide a vehicle for integrating data across datasets, known as transport, even though the causal models (and the associated data) differ. E.g., survey data can be merged with randomized, controlled trial data. Transport offers a solution to the question of
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time and litter size. Opposition to these ideas by prominent statisticians led them to be ignored for the following 40 years (except among animal breeders). Instead scientists relied on correlations, partly at the behest of Wright's critic (and leading statistician),
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Causal models offer a robust technique for identifying appropriate confounding variables. Formally, Z is a confounder if "Y is associated with Z via paths not going through X". These can often be determined using data collected for other studies. Mathematically, if
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is an operator that signals the experimental intervention (doubling the price). The operator indicates performing the minimal change in the world necessary to create the intended effect, a "mini-surgery" on the model with as little change from reality as possible.
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In experiments on such a model, the controlled direct effect (CDE) is computed by forcing the value of the mediator M (do(M = 0)) and randomly assigning some subjects to each of the values of X (do(X=0), do(X=1), ...) and observing the resulting values of Y.
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operator indicates that the experiment explicitly modified the price of toothpaste. Graphically, this blocks any causal factors that would otherwise affect that variable. Diagramatically, this erases all causal arrows pointing at the experimental variable.
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visits (X) from every other year to every year, which encourages flossing (M). Gums (Y) get healthier, either because of the hygienist (direct) or the flossing (mediator/indirect). The experiment is to continue flossing while skipping the hygienist visit.
2925:: Given an ordered pair of variables (X,Y) in a model, a set of confounder variables Z satisfies the backdoor criterion if (1) no confounder variable Z is a descendent of X and (2) all backdoor paths between X and Y are blocked by the set of confounders. 2181:
Regression coefficients can serve as estimates of the causal effect of an instrumental variable on an outcome as long as that effect is not confounded. In this way, instrumental variables allow causal factors to be quantified without data on confounders.
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Traditionally, B was considered to be a confounder, because it is associated with X and with Y but is not on a causal path nor is it a descendant of anything on a causal path. Controlling for B causes it to become a confounder. This is known as M-bias.
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Conditioning on a variable is a mechanism for conducting hypothetical experiments. Conditioning on a variable involves analyzing the values of other variables for a given value of the conditioned variable. In the first example, conditioning on
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The conventional approach to potential outcomes is data-, not model-driven, limiting its ability to untangle causal relationships. It treats causal questions as problems of missing data and gives incorrect answers to even standard scenarios.
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of the two events. Associations have no causal implications. One event could cause the other, the reverse could be true, or both events could be caused by some third event (unhappy hygienist shames shopper into treating their mouth better ).
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advocated replacing correlation with but-for causality (counterfactuals). He referred to humans' ability to envision alternative worlds in which a cause did or not occur, and in which an effect appeared only following its cause. In 1974
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the equations for calculating the values of A and C derived from regression analysis or another technique can be applied, substituting known values from an observation and fixing the value of other variables (the counterfactual).
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as the metric of association. He wrote, "Force as a cause of motion is exactly the same as a tree god as a cause of growth" and that causation was only a "fetish among the inscrutable arcana of modern science". Pearson founded
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represents the values of those variables in a specific context. However, the required set of background variables is indeterminate (multiple sets may increase the probability), as long as probability is the only criterion.
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Because genes vary randomly across populations, presence of a gene typically qualifies as an instrumental variable, implying that in many cases, causality can be quantified using regression on an observational study.
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Refinements to the technique include creating an instrument by conditioning on other variable to block the paths between the instrument and the confounder and combining multiple variables to form a single instrument.
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Counterfactuals consider possibilities that are not found in data, such as whether a nonsmoker would have developed cancer had they instead been a heavy smoker. They are the highest step on Pearl's causality ladder.
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Presuming data for these observable probabilities is available, the ultimate probability can be computed without an experiment, regardless of the existence of other confounding paths and without backdoor adjustment.
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However, a better experiment is to compute the natural direct effect. (NDE) This is the effect determined by leaving the relationship between X and M untouched while intervening on the relationship between X and Y.
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Direct and indirect (mediated) causes can only be distinguished via conducting counterfactuals. Understanding mediation requires holding the mediator constant while intervening on the direct cause. In the model
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When the causal model is a plausible representation of reality and the backdoor criterion is satisfied, then partial regression coefficients can be used as (causal) path coefficients (for linear relationships).
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examining history (of price changes) because the price change may have been for some other reason that could itself affect the second event (a tariff that increases the price of both goods). Mathematically:
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Causal diagrams are independent of the quantitative probabilities that inform them. Changes to those probabilities (e.g., due to technological improvements) do not require changes to the model.
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may be used in the development of a causal model. Causal models can improve study designs by providing clear rules for deciding which independent variables need to be included/controlled for.
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While this is tractable for small problems, as the number of variables and their associated states increase, the probability table (and associated computation time) increases exponentially.
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In 1986 Baron and Kenny introduced principles for detecting and evaluating mediation in a system of linear equations. As of 2014 their paper was the 33rd most-cited of all time. That year
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works for all model relationships (linear and nonlinear). It allows NDE to then be calculated directly from observational data, without interventions or use of counterfactual subscripts.
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causation and probability. They have also been applied to topics of interest to philosophers, such as the logic of counterfactuals, decision theory, and the analysis of actual causation.
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The indirect effect of X on Y is the "increase we would see in Y while holding X constant and increasing M to whatever value M would attain under a unit increase in X".
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whose values are determined by factors outside the model; V is a set of endogenous variables whose values are determined by factors within the model; and E is a set of
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In the late 19th century, the discipline of statistics began to form. After a years-long effort to identify causal rules for domains such as biological inheritance,
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independent. However, the two models do not have the same meaning and can be falsified based on data (that is, if observational data show an association between
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A mediator node modifies the effect of other causes on an outcome (as opposed to simply affecting the outcome). For example, in the chain example above,
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The Mediation Fallacy instead involves conditioning on the mediator if the mediator and the outcome are confounded, as they are in the above model.
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et al.'s critique, which objected that it handled only linear relationships and that robust, model-free presentations of data were more revealing.
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coat patterns. He backed up his then-heretical claims by showing how such analyses could explain the relationship between guinea pig birth weight,
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Noncollapsibility: A difference between the "crude relative risk and the relative risk resulting after adjustment for the potential confounder".
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proposed that any factor that is "causally relevant" to an effect be conditioned on, moving beyond simple probability as the only guide.
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defined a taxonomy of causality, including material, formal, efficient and final causes. Hume rejected Aristotle's taxonomy in favor of
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Statistics revolves around the analysis of relationships among multiple variables. Traditionally, these relationships are described as
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They can allow some questions to be answered from existing observational data without the need for an interventional study such as a
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For example, given a two variable model of Disease and Test (for the disease) the conditional probability table takes the form:
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or the probability of (purchasing) floss given (the purchase of) toothpaste. Associations can also be measured via computing the
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M mediates X's influence on Y, while X also has an unmediated effect on Y. Thus M is held constant, while do(X) is computed.
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The following converts a do expression into a do-free expression by conditioning on the variables along the front-door path.
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If the elements of a blocking path are all unobservable, the backdoor path is not calculable, but if all forward paths from
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The calculus includes three rules for the transformation of conditional probability expressions involving the do operator.
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Epidemiological: A variable associated with X in the population at large and associated with Y among people unexposed to X.
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warned that controlling for a variable Z is valid only if it is highly unlikely to be affected by independent variables.
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uses measured variation in genes of known function to examine the causal effect of a modifiable exposure on disease in
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of observing the other. Example: shoppers who buy toothpaste are more likely to also buy dental floss. Mathematically:
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expunged the notion of causality from much of science as an unprovable special case of association and introduced the
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and others rediscovered path analysis. While reading Blalock's work on path diagrams, Duncan remembered a lecture by
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Mendelian Randomization: Genetic Variants as Instruments for Strengthening Causal Inference in Observational Studies
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More complex queries are possible, in which the do operator is applied (the value is fixed) to multiple variables.
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introduced the concept of a potential outcome, but his paper was not translated from Polish to English until 1990.
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in the case that the variable set Z blocks all paths from W to Y and all arrows leading into X have been deleted.
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that express the value of each endogenous variable as a function of the values of the other variables in U and V.
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Bayesian networks are used commercially in applications such as wireless data error correction and DNA analysis.
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Z matches the definition, but is a mediator, not a confounder, and is an example of controlling for the outcome.
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According to this table, when a patient does not have the disease, the probability of a positive test is 12%.
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A later definition attempted to address this ambiguity by conditioning on background factors. Mathematically:
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can be computed by modifying causal model M (by deleting arrows into X) and computing the outcome for some
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In forks, one cause has multiple effects. The two effects have a common cause. There exists a (non-causal)
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In the context of causal models, potential outcomes are interpreted causally, rather than statistically.
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The three types of connections of three nodes are linear chains, branching forks and merging colliders.
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Definition: A potential outcome for a variable Y is "the value Y would have taken for individual
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https://www.pymc.io/projects/examples/en/latest/causal_inference/interventional_distribution.html
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Chains are straight line connections with arrows pointing from cause to effect. In this model,
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Sixty years after his first paper, Wright published a piece that recapitulated it, following
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does not apply because of anomalies such as threshold effects and binary values. However,
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A confounder node affects multiple outcomes, creating a positive correlation among them.
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introduced the notion of "potential outcomes" as a language for asking causal questions.
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For a specific observation, use the do operator to establish the counterfactual (e.g.,
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Rule 2 permits the replacement of an intervention with an observation or vice versa.:
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Such definitions are inadequate because other relationships (e.g., a common cause for
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without including the mediator vary significantly from an equation that includes it.
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twenty years earlier that mentioned a paper by Wright that in turn mentioned Burks.
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Katan MB (March 1986). "Apolipoprotein E isoforms, serum cholesterol, and cancer".
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that uses observation to find the simplest/most likely explanation) to estimate
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Comparison of two competing causal models (DCM, GCM) used for interpretation of
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Causal models have formal structures with elements with specific properties.
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probability of flossing given the hygienist and without the hygienist, or:
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Riegelman, R. (1979). "Contributory cause: Unnecessary and insufficient".
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is instead called sufficient. A contributory cause may also be necessary.
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is a traversal of the graph between two nodes following causal arrows.
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will occur. Necessary causes are also known as "but-for" causes, as in
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in a causal model. A causal diagram includes a set of variables (or
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Pearl, Judea; Glymour, Madelyn; Jewell, Nicholas P (7 March 2016).
5985:. In Beebee, Helen; Hitchcock, Christopher; Menzies, Peter (eds.). 5755:(Fall 2018 ed.), Metaphysics Research Lab, Stanford University 4484:{\displaystyle Y\leftarrow X\rightarrow M\rightarrow Y\leftarrow U} 2893:{\displaystyle X\leftarrow A\rightarrow B\leftarrow C\rightarrow Y} 432:
One object is associated with another if observing one changes the
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is an instrumental variable, because it has a path to the outcome
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available) a probability-interval statement, such as non-smoker
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The potential outcome is defined at the level of the individual
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Earlier, allegedly incorrect definitions of confounder include:
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have the same independence conditions, because conditioning on
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The above NDE calculation includes counterfactual subscripts (
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with an explicit requirement that the relationships be causal
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in sports) which later led him to the non-causal concept of
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Rule 3 permits the deletion or addition of interventions.:
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Rule 1 permits the addition or deletion of observations.:
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that had led Galton to abandon causality, by resurrecting
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X and Y are confounded (by some confounder variable Z).
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relied purely on probabilities/associations. One event (
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would have a 10-20% chance of cancer, can be computed.
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not applied to a stationary object, it will not move).
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became the theoretical ancestor of causal modeling and
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For example, consider the direct effect of increasing
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The latter is flawed in that given that in the model:
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expressed as causal relationships. The highest level,
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The Book of Why: The New Science of Cause and Effect
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Each value of the mediator has a corresponding CDE.
4211:, had X been assigned the value x". Mathematically: 4086:in the case where no causal paths connect X and Y. 3622:{\displaystyle P(Y|do(X))=\textstyle \sum _{z}\left} 2799:"Any variable that is correlated with both X and Y." 5730: 5728: 5726: 5543:Probability of a positive test for a given disease 6226: 5489: 5318: 5168: 5129: 4944: 4782: 4584: 4483: 4420: 4349: 4284: 4248: 4182: 4075: 3993: 3895: 3699: 3621: 3445: 3425: 3405: 3385: 3365: 3345: 3325: 3305: 3285: 3253: 3233: 3213: 3164: 3144: 3124: 3098: 3078: 3044: 2892: 2839: 2781: 2689: 2669: 2649: 2629: 2605: 2585: 2565: 2545: 2525: 2505: 2482: 2444: 2367: 2329: 2309: 2286: 2266: 2246: 2224: 2137: 2117: 2097: 2077: 2044: 2009: 1989: 1969: 1949: 1929: 1909: 1889: 1869: 1849: 1829: 1797: 1777: 1757: 1737: 1717: 1694: 1650: 1630: 1610: 1587: 1552: 1532: 1512: 1492: 1460: 1425: 1405: 1393:is a mediator in that it mediates the change that 1385: 1319: 1299: 1279: 1259: 1239: 1120:would not have occurred but for the occurrence of 1044: 1024: 1000: 916: 896: 872: 817: 797: 749: 623: 511: 188: 2085:is a mediator, because it modifies the effect of 6476: 6459:Learning Representations using Causal Invariance 5723: 2637:implies that observations for a given value of 268:, which became the world leader in statistics. 5950: 5536:outcomes with their associated probabilities. 4431: 3721: 6024:. In Knauff, Markus; Spohn, Wolfgang (eds.). 5130:{\displaystyle NIE=\sum _{m}xxP(Y=1|X=0,M=m)} 3741:needs attention from an expert in Mathematics 2929:the analysis of the causal effect of X on y. 2337:take binary values, then the assumption that 365:Sociologists originally called causal models 6193: 5673: 3671: 1661:An elaboration of a fork is the confounder: 183: 165: 158:defines a causal model as an ordered triple 116:Causal models can help with the question of 6194:Smith, George Davey; Ebrahim, Shah (2008). 3896:{\displaystyle P(Y|do(X),Z,W)=P(Y|do(X),Z)} 2840:{\displaystyle X\rightarrow Z\rightarrow Y} 2802:Y is associated with Z among the unexposed. 2445:{\displaystyle A\rightarrow B\rightarrow C} 1461:{\displaystyle A\rightarrow B\rightarrow C} 1056:Other attempts to define causality include 769: 6328:The International Journal of Biostatistics 4531:=0), modifying the equations accordingly. 3221:. Effectively, there are conditions where 2700: 2483:{\displaystyle A\leftarrow B\rightarrow C} 2411: 2386: 2045:{\displaystyle A\rightarrow B\leftarrow C} 1588:{\displaystyle A\leftarrow B\rightarrow C} 1520:that can be eliminated by conditioning on 6355: 6144: 6115: 5746: 5706: 5696: 5356: 5293: 5245: 5203: 1160:does not require the prior occurrence of 123:Causal models have found applications in 16:Conceptual model in philosophy of science 6427: 6229:Causal Inference in Statistics: A Primer 6215:chapter 3-3 Controlling Confounding Bias 6150: 6109: 2156: 1144:must imply the subsequent occurrence of 825:). Mathematically this is expressed as: 65: 6408: 6067:. Thomson-Brooks/Cole. pp. 25–26. 5997:10.1093/oxfordhb/9780199279739.001.0001 5753:The Stanford Encyclopedia of Philosophy 3669: 3055: 2177:has no direct influence on the outcome. 1032:is the set of background variables and 6477: 6064:Discrete Mathematics with Applications 5980: 5374: 5371: 5368: 5365: 5362: 5359: 5353: 5350: 5347: 5344: 5341: 5311: 5308: 5305: 5302: 5299: 5296: 5290: 5287: 5284: 5281: 5278: 5275: 5272: 5269: 5266: 5263: 5260: 5257: 5254: 5251: 5248: 5242: 5239: 5236: 5233: 5230: 5227: 5224: 5221: 5218: 5215: 5212: 5209: 5206: 5200: 5197: 5194: 5191: 5188: 3755:may be able to help recruit an expert. 3745:needed to understand do-Operator, see 2907: 2174:has no other path to causal variables; 1917:explains away the correlation between 1167: 1001:{\displaystyle P(Y|X,K=k)>P(Y|K=k)} 410: 6324:"An Introduction to Causal Inference" 6321: 6293: 6251: 6210: 6022:"Causal and Counterfactual Inference" 6019: 5946: 5944: 5942: 5940: 5938: 5936: 5934: 5932: 5930: 5928: 5926: 5924: 5922: 5920: 5918: 5916: 5914: 5912: 5910: 5908: 5906: 5904: 5902: 5900: 5898: 5896: 5894: 5892: 5890: 5888: 5886: 5884: 5882: 5880: 5878: 5876: 5874: 5872: 5870: 5868: 5866: 5864: 5862: 5860: 5858: 5856: 5854: 5852: 5850: 5848: 5846: 5844: 5842: 5840: 5838: 5836: 5834: 5832: 5830: 5828: 5826: 5824: 5822: 5820: 5818: 5816: 5814: 5812: 5810: 5808: 5806: 5804: 5802: 5800: 5798: 5796: 5794: 5792: 5790: 5788: 5734: 5598: 3994:{\displaystyle P(Y|do(X),Z)=P(Y|X,Z)} 2782:{\displaystyle P(Y|X)\neq P(Y|do(X))} 189:{\displaystyle \langle U,V,E\rangle } 6381: 6086: 6084: 5786: 5784: 5782: 5780: 5778: 5776: 5774: 5772: 5770: 5768: 4539:Calculate the values of the output ( 4202: 4193: 3725: 3353:, there are no unblocked paths from 1360: 1327:(with an associated probability). A 1127: 18: 6263: 6060: 5524: 5521:relevantly different participants. 5503: 4306: 1104:must imply the prior occurrence of 1082:necessary, sufficient, contributory 150:Stanford Encyclopedia of Philosophy 13: 4963: 4519:given the propositional evidence. 4421:{\displaystyle Y_{X}(u)=Y_{Mx}(u)} 4318:states that the potential outcome 4005: 3670: 2657:should show no dependence between 1188:. If the likelihood is 100%, then 740: 737: 734: 731: 728: 714: 711: 708: 705: 702: 699: 696: 693: 690: 687: 677: 674: 671: 668: 665: 642: 611: 608: 605: 602: 599: 596: 593: 590: 587: 584: 565: 562: 559: 556: 553: 502: 499: 496: 493: 490: 487: 484: 481: 478: 475: 465: 462: 459: 456: 453: 14: 6511: 6315: 6081: 5765: 4004:in the case that Z satisfies the 1352: 1200: 781:Twentieth century definitions of 306:, development and environment on 6200:. National Academies Press (US). 5988:The Oxford Handbook of Causation 5954:; Mackenzie, Dana (2018-05-15). 4604: 4543:) using the modified equations. 3730: 3636: 1184:must increase the likelihood of 23: 6450: 6428:Hartnett, Kevin (15 May 2018). 6257: 6220: 6187: 6038:10.7551/mitpress/11252.003.0044 5747:Hitchcock, Christopher (2018), 4076:{\displaystyle P(Y|do(X))=P(Y)} 2406: 1112:, however, does not imply that 530: 6300:. Cambridge University Press. 6130:10.1080/00325481.1979.11715231 6054: 6013: 5974: 5740: 5667: 5484: 5472: 5460: 5442: 5430: 5418: 5403: 5391: 5379: 5124: 5099: 5086: 5074: 5071: 5058: 5045: 5036: 5023: 5010: 5004: 4939: 4936: 4924: 4914: 4885: 4876: 4873: 4861: 4851: 4822: 4777: 4774: 4762: 4750: 4738: 4728: 4715: 4706: 4703: 4691: 4679: 4667: 4657: 4644: 4635: 4629: 4576: 4570: 4564: 4475: 4469: 4463: 4457: 4415: 4409: 4390: 4384: 4344: 4338: 4279: 4273: 4243: 4237: 4177: 4174: 4166: 4156: 4147: 4138: 4135: 4127: 4117: 4108: 4070: 4064: 4055: 4052: 4046: 4036: 4029: 3988: 3975: 3968: 3959: 3950: 3944: 3934: 3927: 3890: 3881: 3875: 3865: 3858: 3849: 3834: 3828: 3818: 3811: 3772: 3694: 3691: 3683: 3660: 3608: 3596: 3590: 3565: 3558: 3540: 3533: 3520: 3495: 3492: 3486: 3476: 3469: 3393:, and all backdoor paths from 3313:intercepts all directed paths 3208: 3205: 3199: 3189: 3182: 3116: 3070: 3037: 3025: 3019: 3000: 2993: 2972: 2969: 2963: 2953: 2946: 2884: 2878: 2872: 2866: 2831: 2825: 2776: 2773: 2767: 2757: 2750: 2741: 2734: 2727: 2474: 2468: 2436: 2430: 2274:and is unconfounded, e.g., by 2216: 2210: 2204: 2198: 2185:For example, given the model: 2036: 2030: 1686: 1680: 1674: 1579: 1573: 1452: 1446: 1176:to be a contributory cause of 995: 982: 975: 966: 947: 940: 873:{\displaystyle P(Y|X)>P(Y)} 867: 861: 852: 845: 838: 744: 682: 661: 618: 615: 580: 570: 549: 506: 470: 449: 427: 1: 6165:10.1016/s0140-6736(86)92972-7 5751:, in Zalta, Edward N. (ed.), 5660: 4089: 2148: 2055: 138: 5981:Okasha, Samir (2012-01-12). 5698:10.1371/journal.pbio.1000033 5629:Structural equation modeling 4546: 3106:where no open paths connect 1136:to be a sufficient cause of 1087: 764: 648:would still have bought it? 367:structural equation modeling 7: 6409:Maudlin, Tim (2019-08-30). 6322:Pearl, Judea (2010-02-26). 6294:Pearl, Judea (2009-09-14). 6026:The Handbook of Rationality 5991:. Vol. 1. OUP Oxford. 5607: 4432:Conducting a counterfactual 3743:. The specific problem is: 3722:Interventional distribution 2060: 1808: 1287:indicates that a change in 1096:to be a necessary cause of 1062:statistical hypothesis test 111:randomized controlled trial 36:to comply with Knowledge's 10: 6516: 6287: 6264:Hao, Karen (May 8, 2019). 5635:Path analysis (statistics) 5528: 4534: 4249:{\displaystyle Y_{X=x}(u)} 3641: 3214:{\displaystyle P(Y|do(X))} 2171:has a path to the outcome; 1638:" (i.e., given a value of 1204: 264:and the Biometrics Lab at 230:introduced the concept of 207: 6231:. John Wiley & Sons. 5549: 4498: 4011: 3909: 3793: 2375:does not occur is called 2297:In the above example, if 1837:(for a specific value of 1540:(for a specific value of 1148:. However, another cause 266:University College London 6382:Falk, Dan (2019-03-17). 6061:Epp, Susanna S. (2004). 5169:{\displaystyle Y_{M=M0}} 4350:{\displaystyle Y_{X}(u)} 4285:{\displaystyle Y_{x}(u)} 3785: 1997:are necessary to affect 1413:would otherwise have on 1368: 1334:Causal diagrams include 1195: 1152:may independently cause 1075: 770:Causality vs correlation 49:may contain suggestions. 34:may need to be rewritten 6500:Concepts in metaphysics 6096:www.istarassessment.org 5650:Dynamic causal modeling 3753:WikiProject Mathematics 3241:can act as a proxy for 2701:Confounder/deconfounder 2412:Independence conditions 2393:Mendelian randomization 2387:Mendelian randomization 2368:{\displaystyle Z=0,X=1} 1471: 1340:directed acyclic graphs 1156:. Thus the presence of 255:correlation coefficient 88:structural causal model 6411:"The Why of the World" 6340:10.2202/1557-4679.1203 5983:"Causation in Biology" 5491: 5320: 5170: 5131: 4946: 4784: 4586: 4522: 4485: 4422: 4351: 4286: 4250: 4184: 4077: 3995: 3897: 3701: 3623: 3447: 3427: 3407: 3387: 3367: 3347: 3327: 3307: 3287: 3286:{\displaystyle z\in Z} 3255: 3235: 3215: 3166: 3146: 3126: 3125:{\displaystyle z\to Y} 3100: 3080: 3079:{\displaystyle X\to Y} 3046: 2894: 2841: 2783: 2691: 2671: 2651: 2631: 2607: 2593:after conditioning on 2587: 2567: 2547: 2527: 2507: 2484: 2446: 2369: 2331: 2311: 2288: 2268: 2248: 2226: 2139: 2119: 2105:(an indirect cause of 2099: 2079: 2046: 2011: 1991: 1971: 1951: 1931: 1911: 1891: 1871: 1851: 1831: 1799: 1779: 1759: 1739: 1719: 1696: 1652: 1632: 1612: 1589: 1554: 1534: 1514: 1494: 1462: 1427: 1407: 1387: 1321: 1301: 1281: 1267:with the arrowhead at 1261: 1241: 1219:relationships between 1211:A causal diagram is a 1046: 1026: 1002: 918: 898: 874: 819: 799: 751: 625: 513: 279:solved the problem of 196:, where U is a set of 190: 153: 75: 6462:, ICLR, February 2020 6270:MIT Technology Review 6118:Postgraduate Medicine 6020:Pearl, Judea (2021). 5492: 5321: 5171: 5132: 4947: 4785: 4587: 4486: 4423: 4352: 4287: 4251: 4185: 4078: 3996: 3898: 3702: 3624: 3448: 3428: 3408: 3388: 3368: 3348: 3328: 3308: 3288: 3256: 3236: 3216: 3167: 3147: 3127: 3101: 3081: 3047: 2895: 2842: 2784: 2692: 2672: 2652: 2632: 2608: 2588: 2568: 2548: 2528: 2508: 2485: 2447: 2397:observational studies 2370: 2332: 2312: 2289: 2269: 2249: 2227: 2164:instrumental variable 2157:Instrumental variable 2140: 2120: 2100: 2080: 2047: 2012: 1992: 1972: 1952: 1932: 1912: 1892: 1872: 1852: 1832: 1800: 1780: 1760: 1740: 1725:is a common cause of 1720: 1697: 1653: 1633: 1613: 1590: 1555: 1535: 1515: 1495: 1463: 1428: 1408: 1388: 1322: 1302: 1282: 1262: 1242: 1205:Further information: 1084:or some combination. 1047: 1027: 1003: 919: 899: 875: 820: 800: 752: 626: 514: 285:Mendelian inheritance 191: 142: 69: 5336: 5183: 5144: 4979: 4804: 4617: 4558: 4451: 4371: 4325: 4260: 4218: 4102: 4023: 3921: 3805: 3654: 3463: 3437: 3417: 3397: 3377: 3357: 3337: 3317: 3297: 3271: 3245: 3225: 3176: 3156: 3136: 3110: 3090: 3064: 3056:Frontdoor adjustment 2940: 2860: 2819: 2721: 2681: 2661: 2641: 2621: 2597: 2577: 2557: 2537: 2517: 2497: 2462: 2424: 2341: 2321: 2301: 2278: 2258: 2238: 2192: 2129: 2109: 2089: 2069: 2024: 2001: 1981: 1961: 1941: 1921: 1901: 1881: 1861: 1841: 1821: 1789: 1769: 1749: 1729: 1709: 1668: 1642: 1622: 1602: 1567: 1544: 1524: 1504: 1484: 1478:spurious correlation 1440: 1417: 1397: 1377: 1336:causal loop diagrams 1311: 1291: 1271: 1251: 1231: 1036: 1016: 934: 908: 888: 832: 809: 789: 655: 543: 443: 321:. One exception was 202:structural equations 162: 5544: 4505:abductive reasoning 4006:back-door criterion 3675: 2908:Backdoor adjustment 1765:(which also causes 1307:causes a change in 1168:Contributory causes 411:Ladder of causation 407:said to be absent. 234:(epitomized by the 198:exogenous variables 102:. Several types of 94:that describes the 6092:"Causal Reasoning" 5655:Rubin causal model 5599:Invariants/context 5542: 5487: 5316: 5166: 5127: 5003: 4942: 4780: 4582: 4481: 4418: 4347: 4282: 4246: 4180: 4073: 3991: 3893: 3697: 3674: 3619: 3618: 3613: 3612: 3611: 3553: 3511: 3443: 3423: 3403: 3383: 3363: 3343: 3323: 3303: 3283: 3251: 3231: 3211: 3162: 3142: 3122: 3096: 3076: 3042: 3041: 3040: 2988: 2890: 2837: 2779: 2687: 2667: 2647: 2627: 2603: 2583: 2563: 2543: 2523: 2503: 2480: 2442: 2365: 2327: 2307: 2284: 2264: 2244: 2222: 2135: 2115: 2095: 2075: 2042: 2007: 1987: 1967: 1947: 1927: 1907: 1887: 1867: 1847: 1827: 1795: 1775: 1755: 1735: 1715: 1692: 1648: 1628: 1608: 1585: 1550: 1530: 1510: 1490: 1458: 1423: 1403: 1383: 1317: 1297: 1277: 1257: 1237: 1180:, the presence of 1140:, the presence of 1108:. The presence of 1100:, the presence of 1042: 1022: 998: 914: 894: 870: 815: 795: 747: 621: 509: 186: 76: 6495:Scientific models 6238:978-1-119-18684-7 5587: 5586: 5511:external validity 5450: 5358: 5295: 5247: 5205: 4994: 4509:logical inference 4444:Given the model: 4314:The first law of 4203:Potential outcome 4172: 4153: 4133: 4132:blood cholesterol 4114: 3770: 3769: 3689: 3666: 3544: 3502: 3446:{\displaystyle X} 3426:{\displaystyle Y} 3406:{\displaystyle Z} 3386:{\displaystyle Y} 3366:{\displaystyle Z} 3346:{\displaystyle Y} 3326:{\displaystyle X} 3306:{\displaystyle Z} 3254:{\displaystyle X} 3234:{\displaystyle Z} 3165:{\displaystyle z} 3152:, the set of all 3145:{\displaystyle Z} 3099:{\displaystyle z} 2979: 2690:{\displaystyle C} 2670:{\displaystyle A} 2650:{\displaystyle B} 2630:{\displaystyle B} 2606:{\displaystyle B} 2586:{\displaystyle C} 2566:{\displaystyle A} 2546:{\displaystyle C} 2526:{\displaystyle A} 2506:{\displaystyle B} 2330:{\displaystyle X} 2310:{\displaystyle Z} 2287:{\displaystyle U} 2267:{\displaystyle Y} 2247:{\displaystyle Z} 2138:{\displaystyle C} 2118:{\displaystyle C} 2098:{\displaystyle A} 2078:{\displaystyle B} 2010:{\displaystyle B} 1990:{\displaystyle C} 1970:{\displaystyle A} 1950:{\displaystyle C} 1930:{\displaystyle A} 1910:{\displaystyle B} 1890:{\displaystyle C} 1870:{\displaystyle A} 1850:{\displaystyle B} 1830:{\displaystyle B} 1798:{\displaystyle B} 1778:{\displaystyle A} 1758:{\displaystyle C} 1738:{\displaystyle A} 1718:{\displaystyle B} 1651:{\displaystyle B} 1631:{\displaystyle B} 1611:{\displaystyle B} 1598:"Conditioning on 1553:{\displaystyle B} 1533:{\displaystyle B} 1513:{\displaystyle C} 1493:{\displaystyle A} 1426:{\displaystyle C} 1406:{\displaystyle A} 1386:{\displaystyle B} 1361:Junction patterns 1344:Ishikawa diagrams 1320:{\displaystyle B} 1300:{\displaystyle A} 1280:{\displaystyle B} 1260:{\displaystyle B} 1240:{\displaystyle A} 1128:Sufficient causes 1058:Granger causality 1045:{\displaystyle k} 1025:{\displaystyle K} 917:{\displaystyle Y} 897:{\displaystyle X} 818:{\displaystyle Y} 798:{\displaystyle X} 125:signal processing 118:external validity 64: 63: 38:quality standards 6507: 6470: 6469: 6468: 6467: 6454: 6443: 6441: 6440: 6424: 6422: 6421: 6405: 6403: 6402: 6369: 6359: 6334:(2): Article 7. 6311: 6281: 6280: 6278: 6276: 6261: 6255: 6249: 6243: 6242: 6224: 6218: 6208: 6202: 6201: 6191: 6185: 6184: 6148: 6142: 6141: 6113: 6107: 6106: 6104: 6102: 6088: 6079: 6078: 6058: 6052: 6051: 6017: 6011: 6010: 5978: 5972: 5971: 5948: 5763: 5762: 5761: 5760: 5744: 5738: 5732: 5721: 5720: 5710: 5700: 5671: 5640:Bayesian network 5623:Bayesian network 5545: 5541: 5531:Bayesian network 5525:Bayesian network 5504:Transportability 5496: 5494: 5493: 5488: 5448: 5378: 5377: 5325: 5323: 5322: 5317: 5315: 5314: 5175: 5173: 5172: 5167: 5165: 5164: 5136: 5134: 5133: 5128: 5102: 5061: 5026: 5002: 4957:dental hygienist 4951: 4949: 4948: 4943: 4917: 4906: 4905: 4854: 4843: 4842: 4789: 4787: 4786: 4781: 4731: 4660: 4591: 4589: 4588: 4583: 4490: 4488: 4487: 4482: 4427: 4425: 4424: 4419: 4408: 4407: 4383: 4382: 4356: 4354: 4353: 4348: 4337: 4336: 4316:causal inference 4307:Causal inference 4291: 4289: 4288: 4283: 4272: 4271: 4255: 4253: 4252: 4247: 4236: 4235: 4189: 4187: 4186: 4181: 4173: 4170: 4159: 4154: 4151: 4134: 4131: 4120: 4115: 4112: 4082: 4080: 4079: 4074: 4039: 4000: 3998: 3997: 3992: 3978: 3937: 3902: 3900: 3899: 3894: 3868: 3821: 3765: 3762: 3756: 3734: 3733: 3726: 3706: 3704: 3703: 3698: 3690: 3687: 3676: 3667: 3664: 3628: 3626: 3625: 3620: 3617: 3568: 3552: 3536: 3510: 3479: 3452: 3450: 3449: 3444: 3432: 3430: 3429: 3424: 3412: 3410: 3409: 3404: 3392: 3390: 3389: 3384: 3372: 3370: 3369: 3364: 3352: 3350: 3349: 3344: 3332: 3330: 3329: 3324: 3312: 3310: 3309: 3304: 3292: 3290: 3289: 3284: 3260: 3258: 3257: 3252: 3240: 3238: 3237: 3232: 3220: 3218: 3217: 3212: 3192: 3171: 3169: 3168: 3163: 3151: 3149: 3148: 3143: 3131: 3129: 3128: 3123: 3105: 3103: 3102: 3097: 3085: 3083: 3082: 3077: 3051: 3049: 3048: 3043: 3003: 2987: 2956: 2913:spurious paths. 2899: 2897: 2896: 2891: 2846: 2844: 2843: 2838: 2788: 2786: 2785: 2780: 2760: 2737: 2696: 2694: 2693: 2688: 2676: 2674: 2673: 2668: 2656: 2654: 2653: 2648: 2636: 2634: 2633: 2628: 2612: 2610: 2609: 2604: 2592: 2590: 2589: 2584: 2572: 2570: 2569: 2564: 2552: 2550: 2549: 2544: 2532: 2530: 2529: 2524: 2512: 2510: 2509: 2504: 2489: 2487: 2486: 2481: 2451: 2449: 2448: 2443: 2374: 2372: 2371: 2366: 2336: 2334: 2333: 2328: 2316: 2314: 2313: 2308: 2293: 2291: 2290: 2285: 2273: 2271: 2270: 2265: 2253: 2251: 2250: 2245: 2231: 2229: 2228: 2223: 2144: 2142: 2141: 2136: 2124: 2122: 2121: 2116: 2104: 2102: 2101: 2096: 2084: 2082: 2081: 2076: 2051: 2049: 2048: 2043: 2016: 2014: 2013: 2008: 1996: 1994: 1993: 1988: 1976: 1974: 1973: 1968: 1956: 1954: 1953: 1948: 1936: 1934: 1933: 1928: 1916: 1914: 1913: 1908: 1896: 1894: 1893: 1888: 1876: 1874: 1873: 1868: 1856: 1854: 1853: 1848: 1836: 1834: 1833: 1828: 1805:the confounder. 1804: 1802: 1801: 1796: 1784: 1782: 1781: 1776: 1764: 1762: 1761: 1756: 1744: 1742: 1741: 1736: 1724: 1722: 1721: 1716: 1705:In such models, 1701: 1699: 1698: 1693: 1657: 1655: 1654: 1649: 1637: 1635: 1634: 1629: 1617: 1615: 1614: 1609: 1594: 1592: 1591: 1586: 1559: 1557: 1556: 1551: 1539: 1537: 1536: 1531: 1519: 1517: 1516: 1511: 1499: 1497: 1496: 1491: 1467: 1465: 1464: 1459: 1432: 1430: 1429: 1424: 1412: 1410: 1409: 1404: 1392: 1390: 1389: 1384: 1326: 1324: 1323: 1318: 1306: 1304: 1303: 1298: 1286: 1284: 1283: 1278: 1266: 1264: 1263: 1258: 1246: 1244: 1243: 1238: 1051: 1049: 1048: 1043: 1031: 1029: 1028: 1023: 1007: 1005: 1004: 999: 985: 950: 923: 921: 920: 915: 903: 901: 900: 895: 879: 877: 876: 871: 848: 824: 822: 821: 816: 804: 802: 801: 796: 756: 754: 753: 748: 743: 717: 685: 680: 630: 628: 627: 622: 614: 573: 568: 518: 516: 515: 510: 505: 473: 468: 195: 193: 192: 187: 151: 133:machine learning 98:mechanisms of a 92:conceptual model 59: 56: 50: 27: 19: 6515: 6514: 6510: 6509: 6508: 6506: 6505: 6504: 6485:Causal diagrams 6475: 6474: 6473: 6465: 6463: 6456: 6455: 6451: 6438: 6436: 6434:Quanta Magazine 6419: 6417: 6400: 6398: 6373:Causal modeling 6318: 6308: 6290: 6285: 6284: 6274: 6272: 6262: 6258: 6250: 6246: 6239: 6225: 6221: 6209: 6205: 6192: 6188: 6159:(8479): 507–8. 6149: 6145: 6114: 6110: 6100: 6098: 6090: 6089: 6082: 6075: 6059: 6055: 6048: 6018: 6014: 6007: 5979: 5975: 5968: 5960:. Basic Books. 5949: 5766: 5758: 5756: 5749:"Causal Models" 5745: 5741: 5733: 5724: 5691:(2): e1000033. 5672: 5668: 5663: 5610: 5601: 5533: 5527: 5506: 5340: 5339: 5337: 5334: 5333: 5187: 5186: 5184: 5181: 5180: 5151: 5147: 5145: 5142: 5141: 5098: 5057: 5022: 4998: 4980: 4977: 4976: 4966: 4964:Indirect effect 4913: 4892: 4888: 4850: 4829: 4825: 4805: 4802: 4801: 4727: 4656: 4618: 4615: 4614: 4607: 4559: 4556: 4555: 4549: 4537: 4525: 4501: 4452: 4449: 4448: 4434: 4400: 4396: 4378: 4374: 4372: 4369: 4368: 4332: 4328: 4326: 4323: 4322: 4309: 4267: 4263: 4261: 4258: 4257: 4225: 4221: 4219: 4216: 4215: 4205: 4196: 4194:Counterfactuals 4169: 4155: 4150: 4130: 4116: 4111: 4103: 4100: 4099: 4092: 4035: 4024: 4021: 4020: 4014: 3974: 3933: 3922: 3919: 3918: 3912: 3864: 3817: 3806: 3803: 3802: 3796: 3788: 3780:polynomial time 3775: 3766: 3760: 3757: 3751: 3735: 3731: 3724: 3686: 3668: 3663: 3655: 3652: 3651: 3644: 3639: 3564: 3548: 3532: 3512: 3506: 3475: 3464: 3461: 3460: 3438: 3435: 3434: 3433:are blocked by 3418: 3415: 3414: 3398: 3395: 3394: 3378: 3375: 3374: 3358: 3355: 3354: 3338: 3335: 3334: 3318: 3315: 3314: 3298: 3295: 3294: 3272: 3269: 3268: 3246: 3243: 3242: 3226: 3223: 3222: 3188: 3177: 3174: 3173: 3172:s, can measure 3157: 3154: 3153: 3137: 3134: 3133: 3111: 3108: 3107: 3091: 3088: 3087: 3065: 3062: 3061: 3058: 2999: 2983: 2952: 2941: 2938: 2937: 2910: 2861: 2858: 2857: 2820: 2817: 2816: 2756: 2733: 2722: 2719: 2718: 2703: 2682: 2679: 2678: 2662: 2659: 2658: 2642: 2639: 2638: 2622: 2619: 2618: 2598: 2595: 2594: 2578: 2575: 2574: 2558: 2555: 2554: 2538: 2535: 2534: 2518: 2515: 2514: 2498: 2495: 2494: 2463: 2460: 2459: 2425: 2422: 2421: 2414: 2409: 2389: 2342: 2339: 2338: 2322: 2319: 2318: 2302: 2299: 2298: 2279: 2276: 2275: 2259: 2256: 2255: 2239: 2236: 2235: 2193: 2190: 2189: 2159: 2151: 2145:(the outcome). 2130: 2127: 2126: 2110: 2107: 2106: 2090: 2087: 2086: 2070: 2067: 2066: 2063: 2058: 2025: 2022: 2021: 2002: 1999: 1998: 1982: 1979: 1978: 1962: 1959: 1958: 1942: 1939: 1938: 1922: 1919: 1918: 1902: 1899: 1898: 1882: 1879: 1878: 1862: 1859: 1858: 1842: 1839: 1838: 1822: 1819: 1818: 1811: 1790: 1787: 1786: 1770: 1767: 1766: 1750: 1747: 1746: 1730: 1727: 1726: 1710: 1707: 1706: 1669: 1666: 1665: 1643: 1640: 1639: 1623: 1620: 1619: 1618:" means "given 1603: 1600: 1599: 1568: 1565: 1564: 1545: 1542: 1541: 1525: 1522: 1521: 1505: 1502: 1501: 1485: 1482: 1481: 1474: 1441: 1438: 1437: 1418: 1415: 1414: 1398: 1395: 1394: 1378: 1375: 1374: 1371: 1363: 1355: 1312: 1309: 1308: 1292: 1289: 1288: 1272: 1269: 1268: 1252: 1249: 1248: 1232: 1229: 1228: 1209: 1203: 1198: 1170: 1130: 1090: 1080:A cause can be 1078: 1037: 1034: 1033: 1017: 1014: 1013: 981: 946: 935: 932: 931: 909: 906: 905: 889: 886: 885: 844: 833: 830: 829: 810: 807: 806: 790: 787: 786: 772: 767: 727: 686: 681: 664: 656: 653: 652: 645: 643:Counterfactuals 583: 569: 552: 544: 541: 540: 533: 474: 469: 452: 444: 441: 440: 430: 422:Counterfactuals 415:Pearl's causal 413: 281:trait stability 236:sophomore slump 232:mean regression 217:counterfactuals 210: 163: 160: 159: 152: 149: 141: 104:causal notation 60: 54: 51: 41: 28: 17: 12: 11: 5: 6513: 6503: 6502: 6497: 6492: 6487: 6472: 6471: 6448: 6447: 6446: 6444: 6425: 6406: 6379: 6370: 6317: 6316:External links 6314: 6313: 6312: 6306: 6289: 6286: 6283: 6282: 6256: 6254:, p. 207. 6244: 6237: 6219: 6203: 6186: 6143: 6124:(2): 177–179. 6108: 6080: 6073: 6053: 6046: 6012: 6005: 5973: 5966: 5764: 5739: 5722: 5665: 5664: 5662: 5659: 5658: 5657: 5652: 5647: 5642: 5637: 5632: 5626: 5619:Causal network 5616: 5609: 5606: 5600: 5597: 5585: 5584: 5581: 5578: 5574: 5573: 5570: 5567: 5563: 5562: 5559: 5556: 5552: 5551: 5548: 5529:Main article: 5526: 5523: 5505: 5502: 5498: 5497: 5486: 5483: 5480: 5477: 5474: 5471: 5468: 5465: 5462: 5459: 5456: 5453: 5447: 5444: 5441: 5438: 5435: 5432: 5429: 5426: 5423: 5420: 5417: 5414: 5411: 5408: 5405: 5402: 5399: 5396: 5393: 5390: 5387: 5384: 5381: 5376: 5373: 5370: 5367: 5364: 5361: 5355: 5352: 5349: 5346: 5343: 5327: 5326: 5313: 5310: 5307: 5304: 5301: 5298: 5292: 5289: 5286: 5283: 5280: 5277: 5274: 5271: 5268: 5265: 5262: 5259: 5256: 5253: 5250: 5244: 5241: 5238: 5235: 5232: 5229: 5226: 5223: 5220: 5217: 5214: 5211: 5208: 5202: 5199: 5196: 5193: 5190: 5163: 5160: 5157: 5154: 5150: 5138: 5137: 5126: 5123: 5120: 5117: 5114: 5111: 5108: 5105: 5101: 5097: 5094: 5091: 5088: 5085: 5082: 5079: 5076: 5073: 5070: 5067: 5064: 5060: 5056: 5053: 5050: 5047: 5044: 5041: 5038: 5035: 5032: 5029: 5025: 5021: 5018: 5015: 5012: 5009: 5006: 5001: 4997: 4993: 4990: 4987: 4984: 4965: 4962: 4953: 4952: 4941: 4938: 4935: 4932: 4929: 4926: 4923: 4920: 4916: 4912: 4909: 4904: 4901: 4898: 4895: 4891: 4887: 4884: 4881: 4878: 4875: 4872: 4869: 4866: 4863: 4860: 4857: 4853: 4849: 4846: 4841: 4838: 4835: 4832: 4828: 4824: 4821: 4818: 4815: 4812: 4809: 4791: 4790: 4779: 4776: 4773: 4770: 4767: 4764: 4761: 4758: 4755: 4752: 4749: 4746: 4743: 4740: 4737: 4734: 4730: 4726: 4723: 4720: 4717: 4714: 4711: 4708: 4705: 4702: 4699: 4696: 4693: 4690: 4687: 4684: 4681: 4678: 4675: 4672: 4669: 4666: 4663: 4659: 4655: 4652: 4649: 4646: 4643: 4640: 4637: 4634: 4631: 4628: 4625: 4622: 4606: 4603: 4581: 4578: 4575: 4572: 4569: 4566: 4563: 4548: 4545: 4536: 4533: 4524: 4521: 4500: 4497: 4492: 4491: 4480: 4477: 4474: 4471: 4468: 4465: 4462: 4459: 4456: 4433: 4430: 4429: 4428: 4417: 4414: 4411: 4406: 4403: 4399: 4395: 4392: 4389: 4386: 4381: 4377: 4358: 4357: 4346: 4343: 4340: 4335: 4331: 4308: 4305: 4294: 4293: 4281: 4278: 4275: 4270: 4266: 4245: 4242: 4239: 4234: 4231: 4228: 4224: 4204: 4201: 4195: 4192: 4191: 4190: 4179: 4176: 4168: 4165: 4162: 4158: 4149: 4146: 4143: 4140: 4137: 4129: 4126: 4123: 4119: 4110: 4107: 4091: 4088: 4084: 4083: 4072: 4069: 4066: 4063: 4060: 4057: 4054: 4051: 4048: 4045: 4042: 4038: 4034: 4031: 4028: 4013: 4010: 4002: 4001: 3990: 3987: 3984: 3981: 3977: 3973: 3970: 3967: 3964: 3961: 3958: 3955: 3952: 3949: 3946: 3943: 3940: 3936: 3932: 3929: 3926: 3911: 3908: 3904: 3903: 3892: 3889: 3886: 3883: 3880: 3877: 3874: 3871: 3867: 3863: 3860: 3857: 3854: 3851: 3848: 3845: 3842: 3839: 3836: 3833: 3830: 3827: 3824: 3820: 3816: 3813: 3810: 3795: 3792: 3787: 3784: 3774: 3771: 3768: 3767: 3738: 3736: 3729: 3723: 3720: 3708: 3707: 3696: 3693: 3685: 3682: 3679: 3673: 3662: 3659: 3643: 3640: 3638: 3635: 3630: 3629: 3616: 3610: 3607: 3604: 3601: 3598: 3595: 3592: 3589: 3586: 3583: 3580: 3577: 3574: 3571: 3567: 3563: 3560: 3557: 3551: 3547: 3542: 3539: 3535: 3531: 3528: 3525: 3522: 3519: 3515: 3509: 3505: 3500: 3497: 3494: 3491: 3488: 3485: 3482: 3478: 3474: 3471: 3468: 3442: 3422: 3402: 3382: 3362: 3342: 3322: 3302: 3282: 3279: 3276: 3250: 3230: 3210: 3207: 3204: 3201: 3198: 3195: 3191: 3187: 3184: 3181: 3161: 3141: 3121: 3118: 3115: 3095: 3086:have elements 3075: 3072: 3069: 3057: 3054: 3053: 3052: 3039: 3036: 3033: 3030: 3027: 3024: 3021: 3018: 3015: 3012: 3009: 3006: 3002: 2998: 2995: 2992: 2986: 2982: 2977: 2974: 2971: 2968: 2965: 2962: 2959: 2955: 2951: 2948: 2945: 2909: 2906: 2901: 2900: 2889: 2886: 2883: 2880: 2877: 2874: 2871: 2868: 2865: 2848: 2847: 2836: 2833: 2830: 2827: 2824: 2810: 2809: 2806: 2803: 2800: 2790: 2789: 2778: 2775: 2772: 2769: 2766: 2763: 2759: 2755: 2752: 2749: 2746: 2743: 2740: 2736: 2732: 2729: 2726: 2702: 2699: 2686: 2666: 2646: 2626: 2602: 2582: 2562: 2542: 2522: 2502: 2491: 2490: 2479: 2476: 2473: 2470: 2467: 2453: 2452: 2441: 2438: 2435: 2432: 2429: 2413: 2410: 2408: 2405: 2388: 2385: 2364: 2361: 2358: 2355: 2352: 2349: 2346: 2326: 2306: 2283: 2263: 2243: 2233: 2232: 2221: 2218: 2215: 2212: 2209: 2206: 2203: 2200: 2197: 2179: 2178: 2175: 2172: 2158: 2155: 2150: 2147: 2134: 2114: 2094: 2074: 2062: 2059: 2057: 2054: 2053: 2052: 2041: 2038: 2035: 2032: 2029: 2006: 1986: 1966: 1946: 1926: 1906: 1886: 1866: 1846: 1826: 1810: 1807: 1794: 1774: 1754: 1734: 1714: 1703: 1702: 1691: 1688: 1685: 1682: 1679: 1676: 1673: 1647: 1627: 1607: 1596: 1595: 1584: 1581: 1578: 1575: 1572: 1549: 1529: 1509: 1489: 1473: 1470: 1469: 1468: 1457: 1454: 1451: 1448: 1445: 1422: 1402: 1382: 1370: 1367: 1362: 1359: 1354: 1353:Model elements 1351: 1316: 1296: 1276: 1256: 1236: 1215:that displays 1213:directed graph 1202: 1201:Causal diagram 1199: 1197: 1194: 1169: 1166: 1129: 1126: 1089: 1086: 1077: 1074: 1041: 1021: 1010: 1009: 997: 994: 991: 988: 984: 980: 977: 974: 971: 968: 965: 962: 959: 956: 953: 949: 945: 942: 939: 913: 893: 882: 881: 869: 866: 863: 860: 857: 854: 851: 847: 843: 840: 837: 814: 794: 771: 768: 766: 763: 758: 757: 746: 742: 739: 736: 733: 730: 726: 723: 720: 716: 713: 710: 707: 704: 701: 698: 695: 692: 689: 684: 679: 676: 673: 670: 667: 663: 660: 644: 641: 632: 631: 620: 617: 613: 610: 607: 604: 601: 598: 595: 592: 589: 586: 582: 579: 576: 572: 567: 564: 561: 558: 555: 551: 548: 532: 529: 520: 519: 508: 504: 501: 498: 495: 492: 489: 486: 483: 480: 477: 472: 467: 464: 461: 458: 455: 451: 448: 429: 426: 412: 409: 346:In the 1960s, 223:" causation). 209: 206: 185: 182: 179: 176: 173: 170: 167: 147: 140: 137: 62: 61: 31: 29: 22: 15: 9: 6: 4: 3: 2: 6512: 6501: 6498: 6496: 6493: 6491: 6488: 6486: 6483: 6482: 6480: 6461: 6460: 6453: 6449: 6445: 6435: 6431: 6426: 6416: 6415:Boston Review 6412: 6407: 6397: 6393: 6389: 6385: 6380: 6378: 6374: 6371: 6367: 6363: 6358: 6353: 6349: 6345: 6341: 6337: 6333: 6329: 6325: 6320: 6319: 6309: 6307:9781139643986 6303: 6299: 6298: 6292: 6291: 6271: 6267: 6260: 6253: 6248: 6240: 6234: 6230: 6223: 6216: 6212: 6207: 6199: 6198: 6190: 6182: 6178: 6174: 6170: 6166: 6162: 6158: 6154: 6147: 6139: 6135: 6131: 6127: 6123: 6119: 6112: 6097: 6093: 6087: 6085: 6076: 6074:9780534359454 6070: 6066: 6065: 6057: 6049: 6047:9780262366175 6043: 6039: 6035: 6031: 6027: 6023: 6016: 6008: 6006:9780191629464 6002: 5998: 5994: 5990: 5989: 5984: 5977: 5969: 5967:9780465097616 5963: 5959: 5958: 5953: 5947: 5945: 5943: 5941: 5939: 5937: 5935: 5933: 5931: 5929: 5927: 5925: 5923: 5921: 5919: 5917: 5915: 5913: 5911: 5909: 5907: 5905: 5903: 5901: 5899: 5897: 5895: 5893: 5891: 5889: 5887: 5885: 5883: 5881: 5879: 5877: 5875: 5873: 5871: 5869: 5867: 5865: 5863: 5861: 5859: 5857: 5855: 5853: 5851: 5849: 5847: 5845: 5843: 5841: 5839: 5837: 5835: 5833: 5831: 5829: 5827: 5825: 5823: 5821: 5819: 5817: 5815: 5813: 5811: 5809: 5807: 5805: 5803: 5801: 5799: 5797: 5795: 5793: 5791: 5789: 5787: 5785: 5783: 5781: 5779: 5777: 5775: 5773: 5771: 5769: 5754: 5750: 5743: 5736: 5731: 5729: 5727: 5718: 5714: 5709: 5704: 5699: 5694: 5690: 5686: 5685: 5680: 5676: 5670: 5666: 5656: 5653: 5651: 5648: 5646: 5643: 5641: 5638: 5636: 5633: 5630: 5627: 5624: 5620: 5617: 5615: 5614:Causal system 5612: 5611: 5605: 5596: 5593: 5590: 5582: 5579: 5576: 5575: 5571: 5568: 5565: 5564: 5560: 5557: 5554: 5553: 5547: 5546: 5540: 5537: 5532: 5522: 5518: 5514: 5512: 5501: 5481: 5478: 5475: 5469: 5466: 5463: 5457: 5454: 5451: 5445: 5439: 5436: 5433: 5427: 5424: 5421: 5415: 5412: 5409: 5406: 5400: 5397: 5394: 5388: 5385: 5382: 5332: 5331: 5330: 5179: 5178: 5177: 5161: 5158: 5155: 5152: 5148: 5121: 5118: 5115: 5112: 5109: 5106: 5103: 5095: 5092: 5089: 5083: 5080: 5077: 5068: 5065: 5062: 5054: 5051: 5048: 5042: 5039: 5033: 5030: 5027: 5019: 5016: 5013: 5007: 4999: 4995: 4991: 4988: 4985: 4982: 4975: 4974: 4973: 4969: 4961: 4958: 4933: 4930: 4927: 4921: 4918: 4910: 4907: 4902: 4899: 4896: 4893: 4889: 4882: 4879: 4870: 4867: 4864: 4858: 4855: 4847: 4844: 4839: 4836: 4833: 4830: 4826: 4819: 4816: 4813: 4810: 4807: 4800: 4799: 4798: 4794: 4771: 4768: 4765: 4759: 4756: 4753: 4747: 4744: 4741: 4735: 4732: 4724: 4721: 4718: 4712: 4709: 4700: 4697: 4694: 4688: 4685: 4682: 4676: 4673: 4670: 4664: 4661: 4653: 4650: 4647: 4641: 4638: 4632: 4626: 4623: 4620: 4613: 4612: 4611: 4605:Direct effect 4602: 4598: 4595: 4592: 4579: 4573: 4567: 4561: 4553: 4544: 4542: 4532: 4530: 4520: 4518: 4514: 4510: 4506: 4496: 4478: 4472: 4466: 4460: 4454: 4447: 4446: 4445: 4442: 4440: 4412: 4404: 4401: 4397: 4393: 4387: 4379: 4375: 4367: 4366: 4365: 4363: 4341: 4333: 4329: 4321: 4320: 4319: 4317: 4312: 4304: 4300: 4299: 4276: 4268: 4264: 4240: 4232: 4229: 4226: 4222: 4214: 4213: 4212: 4210: 4200: 4163: 4160: 4152:Heart disease 4144: 4141: 4124: 4121: 4113:Heart disease 4105: 4098: 4097: 4096: 4087: 4067: 4061: 4058: 4049: 4043: 4040: 4032: 4026: 4019: 4018: 4017: 4009: 4007: 3985: 3982: 3979: 3971: 3965: 3962: 3956: 3953: 3947: 3941: 3938: 3930: 3924: 3917: 3916: 3915: 3907: 3887: 3884: 3878: 3872: 3869: 3861: 3855: 3852: 3846: 3843: 3840: 3837: 3831: 3825: 3822: 3814: 3808: 3801: 3800: 3799: 3791: 3783: 3781: 3764: 3754: 3750: 3748: 3742: 3739:This article 3737: 3728: 3727: 3719: 3716: 3713: 3680: 3677: 3657: 3650: 3649: 3648: 3637:Interventions 3634: 3614: 3605: 3602: 3599: 3593: 3587: 3584: 3581: 3578: 3575: 3572: 3569: 3561: 3555: 3549: 3545: 3537: 3529: 3526: 3523: 3517: 3513: 3507: 3503: 3498: 3489: 3483: 3480: 3472: 3466: 3459: 3458: 3457: 3454: 3440: 3420: 3400: 3380: 3360: 3340: 3320: 3300: 3280: 3277: 3274: 3266: 3262: 3248: 3228: 3202: 3196: 3193: 3185: 3179: 3159: 3139: 3119: 3113: 3093: 3073: 3067: 3034: 3031: 3028: 3022: 3016: 3013: 3010: 3007: 3004: 2996: 2990: 2984: 2980: 2975: 2966: 2960: 2957: 2949: 2943: 2936: 2935: 2934: 2930: 2926: 2924: 2920: 2918: 2914: 2905: 2887: 2881: 2875: 2869: 2863: 2856: 2855: 2854: 2853:In the model 2851: 2834: 2828: 2822: 2815: 2814: 2813: 2807: 2804: 2801: 2798: 2797: 2796: 2793: 2770: 2764: 2761: 2753: 2747: 2744: 2738: 2730: 2724: 2717: 2716: 2715: 2711: 2709: 2698: 2684: 2664: 2644: 2624: 2614: 2600: 2580: 2560: 2540: 2520: 2500: 2477: 2471: 2465: 2458: 2457: 2456: 2439: 2433: 2427: 2420: 2419: 2418: 2404: 2400: 2398: 2394: 2384: 2380: 2378: 2362: 2359: 2356: 2353: 2350: 2347: 2344: 2324: 2304: 2295: 2281: 2261: 2241: 2219: 2213: 2207: 2201: 2195: 2188: 2187: 2186: 2183: 2176: 2173: 2170: 2169: 2168: 2167:is one that: 2166: 2165: 2154: 2146: 2132: 2112: 2092: 2072: 2039: 2033: 2027: 2020: 2019: 2018: 2004: 1984: 1964: 1944: 1924: 1904: 1884: 1864: 1844: 1824: 1816: 1806: 1792: 1772: 1752: 1732: 1712: 1689: 1683: 1677: 1671: 1664: 1663: 1662: 1659: 1645: 1625: 1605: 1582: 1576: 1570: 1563: 1562: 1561: 1547: 1527: 1507: 1487: 1479: 1455: 1449: 1443: 1436: 1435: 1434: 1420: 1400: 1380: 1366: 1358: 1350: 1347: 1345: 1341: 1337: 1332: 1330: 1314: 1294: 1274: 1254: 1234: 1226: 1222: 1218: 1214: 1208: 1193: 1191: 1187: 1183: 1179: 1175: 1165: 1163: 1159: 1155: 1151: 1147: 1143: 1139: 1135: 1125: 1123: 1119: 1115: 1111: 1107: 1103: 1099: 1095: 1085: 1083: 1073: 1071: 1067: 1063: 1059: 1054: 1039: 1019: 992: 989: 986: 978: 972: 969: 963: 960: 957: 954: 951: 943: 937: 930: 929: 928: 925: 911: 891: 864: 858: 855: 849: 841: 835: 828: 827: 826: 812: 792: 784: 779: 777: 762: 724: 721: 718: 658: 651: 650: 649: 640: 637: 577: 574: 546: 539: 538: 537: 528: 525: 446: 439: 438: 437: 435: 425: 423: 418: 408: 405: 401: 396: 394: 389: 387: 382: 377: 375: 370: 368: 363: 361: 357: 353: 349: 344: 342: 337: 335: 330: 328: 324: 320: 315: 314: 309: 305: 301: 300:causal graphs 297: 296:path analysis 293: 288: 286: 282: 278: 274: 269: 267: 263: 262: 256: 252: 248: 243: 241: 237: 233: 229: 224: 222: 218: 214: 205: 203: 199: 180: 177: 174: 171: 168: 157: 146: 136: 134: 130: 126: 121: 119: 114: 112: 107: 105: 101: 97: 93: 89: 85: 81: 73: 68: 58: 48: 44: 39: 35: 32:This article 30: 26: 21: 20: 6464:, retrieved 6458: 6452: 6437:. Retrieved 6433: 6418:. Retrieved 6414: 6399:. Retrieved 6387: 6331: 6327: 6296: 6275:February 10, 6273:. Retrieved 6269: 6259: 6247: 6228: 6222: 6206: 6196: 6189: 6156: 6152: 6146: 6121: 6117: 6111: 6099:. Retrieved 6095: 6063: 6056: 6025: 6015: 5987: 5976: 5956: 5952:Pearl, Judea 5757:, retrieved 5752: 5742: 5688: 5684:PLOS Biology 5682: 5677:(Feb 2009). 5675:Karl Friston 5669: 5602: 5594: 5591: 5588: 5538: 5534: 5519: 5515: 5507: 5499: 5328: 5139: 4970: 4967: 4954: 4795: 4792: 4608: 4599: 4596: 4593: 4554: 4550: 4540: 4538: 4528: 4526: 4516: 4512: 4502: 4493: 4443: 4438: 4435: 4364:. 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Index


quality standards
You can help
talk page

fMRI
metaphysics
conceptual model
causal
system
causal notation
randomized controlled trial
signal processing
epidemiology
machine learning
Judea Pearl
exogenous variables
structural equations
Aristotle
counterfactuals
but-for
Galton
mean regression
sophomore slump
correlation
positivist
Pearson
correlation coefficient
Biometrika
University College London

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