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250:
years. However, David
Stewart convinced Birney to choose a winner by pointing out that the rules specified that a winner had to be chosen in 2003, with no exceptions. Birney noted that, though the exact number was still unknown, there was no doubt that the number of human genes was much less than 26,000, and he announced that 21,000 was the best estimate in a 2003 talk.
207:
conference in 2000. Initially, bets could be placed for $ 1, which was raised to $ 5 in 2001 and to $ 20 in 2002. The cost of placing a bet increased significantly because later participants were expected to have much more accurate information available to inform their guesses. By May 23, 2000, 228
249:
had always been planned to end in 2003, because Birney had expected that
Ensembl would have completed counting the number of human genes by then. Once it became clear that they would need more time to arrive at an exact number, Birney initially planned on extending the sweepstakes for five more
244:
of
Genoscope with convincing her that the true number of human genes would be relatively low. All three winners shared the prize because they were the only betters who guessed under 30,000, and Birney was certain that the total number of genes was less than that. The
29:
232:. In addition to being the winning guess, this was also the lowest of the more than 460 bets that were placed. Rowen split the $ 1,200 prize pool with Paul Dear of the
258:
As of 2018 there is continuing debate amongst scientists about the total number of genes in the human genome, with most estimates ranging from 19,000 and 22,000.
894:
1223:
228:. Rowen had guessed that the human genome would contain 25,947 genes, which was the closest to the estimated number of 24,847 given by the
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bets had been placed, with the average number of predicted genes among them being 62,598.
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596:(2003). "Bioinformatics: Gene Counters Struggle to Get the Right Answer".
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95:
895:"Scientists Cast Bets on Human Genes; A Winner Will Be Picked in 2003"
1091:"Between a chicken and a grape: estimating the number of human genes"
816:
799:
237:
224:, who had organized the pool, announced the winner: Lee Rowen of the
554:
537:
307:
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113:
109:
767:
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499:. Methods in Molecular Biology. Vol. 258. pp. 153–166.
85:
196:
928:
Pearson, Helen (2003). "Human gene number wager won".
993:"Gene Sweepstakes Ends, but Winner May Well Be Wrong"
495:
Leach, Martin (2004). "Gene
Expression Informatics".
370:"Top genome researchers gather at Cold Spring Harbor"
44:
May 10, 2000 – May 30, 2003
1078:
1205:
800:"Researchers take a gamble on the human genome"
393:Proceedings of the National Academy of Sciences
1084:
1188:
195:for scientists to bet on the total number of
1019:
253:
921:
791:
649:"Gene prediction: the end of the beginning"
283:"Geneticists play the numbers game in vain"
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854:Journal of the National Cancer Institute
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123:Estimating total number of genes in the
1224:Internet properties established in 2000
1028:"New human gene tally reignites debate"
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367:
456:"Who'll sweep the Gene Sweepstake?"
13:
203:. The sweepstake was started at a
14:
1240:
222:European Bioinformatics Institute
1151:
961:"Low Numbers Win GeneSweep Pool"
473:10.1186/gb-spotlight-20030430-01
376:. Cold Spring Harbor Laboratory.
981:
952:
883:
840:
740:
666:10.1186/gb-2000-1-2-reports4012
347:"Gene Sweepstake ("Genesweep")"
230:Ensembl genome database project
76:Ensembl genome database project
640:
361:
1:
709:10.1016/S0960-9822(00)00590-X
610:10.1126/science.301.5636.1040
261:
236:(MRC) and Olivier Jaillon of
226:Institute for Systems Biology
205:Cold Spring Harbor Laboratory
72:Cold Spring Harbor Laboratory
63:3 years and 20 days
1167:. You can help Knowledge by
1026:Willyard, Cassandra (2018).
16:Online genetics betting pool
7:
959:Pennisi, Elizabeth (2003).
680:Harris, Richard F. (2000).
389:"The drifting human genome"
10:
1245:
1146:
1055:10.1038/d41586-018-05462-w
749:"The nature of the number"
36:GeneSweep: Gene Sweepstake
505:10.1385/1-59259-751-3:153
497:Gene Expression Profiling
466:: spotlight-20030430-01.
254:Ongoing debate after 2003
158:
150:
142:
130:
119:
105:
91:
81:
67:
59:
40:
1110:10.1186/gb-2010-11-5-206
849:"Gambling on the Genome"
454:Choi, Charles Q (2003).
234:Medical Research Council
868:10.1093/jnci/92.17.1373
414:10.1073/pnas.0710524104
387:Zhang, Jianzhi (2007).
18:
798:Smaglik, Paul (2000).
647:Semple, Colin (2000).
30:considered for merging
345:Birney, Ewan (2000).
938:10.1038/news030602-3
659:(2): reports4012.1.
212:Winning bets in 2003
1046:2018Natur.558..354W
700:2000CBio...10.R506H
604:(5636): 1040–1041.
536:Giles, Jim (2002).
405:2007PNAS..10420147Z
399:(51): 20147–20148.
299:2003Natur.423..576P
37:
1087:Salzberg, Steven L
998:The New York Times
900:The New York Times
594:Pennisi, Elizabeth
35:
1219:Betting exchanges
1176:
1175:
1085:Pertea, Mihaela;
1040:(7710): 354–355.
548:(6914): 354–355.
240:. Rowen credited
216:On May 30, 2003,
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353:. Archived from
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682:"The gene pool"
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989:Wade, Nicholas
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891:Wade, Nicholas
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761:(2): 127–128.
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653:Genome Biology
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460:Genome Biology
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154:$ 1,200 prize
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25:Infobox event
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1169:expanding it
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538:"Wanna bet?"
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355:the original
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201:human genome
184:
180:
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143:Participants
131:Organised by
125:human genome
23:
351:ensembl.org
247:sweepstakes
218:Ewan Birney
135:Ewan Birney
19:‹ The
1208:Categories
1103:(5): 206.
1012:2019-10-21
974:2019-10-21
914:2019-10-21
262:References
189:sweepstake
170:/genesweep
96:Sweepstake
52:2003-05-30
48:2000-05-10
1119:1465-6906
1064:0028-0836
1007:0362-4331
946:0028-0836
909:0362-4331
826:0028-0836
777:1061-4036
718:0960-9822
618:0036-8075
564:0028-0836
482:1465-6906
423:0027-8424
317:0028-0836
238:Genoscope
181:GeneSweep
28:is being
1161:genetics
1137:20441615
1089:(2010).
1072:29921859
991:(2003).
893:(2000).
877:10974068
834:10830930
785:10835616
734:20616324
726:10899015
626:12933991
572:12459753
523:14970462
441:18093959
374:cshl.edu
325:12789304
281:(2003).
166:.ensembl
146:460 bets
114:Genomics
110:Genetics
82:Location
60:Duration
50: –
32:. ›
21:template
1128:2898077
1042:Bibcode
969:Science
696:Bibcode
634:5227212
598:Science
580:4356650
432:2154398
401:Bibcode
295:Bibcode
220:of the
199:in the
159:Website
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287:Nature
187:was a
151:Awards
120:Motive
86:Global
1159:This
730:S2CID
630:S2CID
576:S2CID
197:genes
172:.html
106:Theme
68:Venue
1165:stub
1133:PMID
1115:ISSN
1068:PMID
1060:ISSN
1003:ISSN
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830:PMID
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560:ISSN
519:PMID
509:ISBN
478:ISSN
437:PMID
419:ISSN
321:PMID
313:ISSN
191:and
168:.org
92:Type
41:Date
1123:PMC
1105:doi
1050:doi
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934:doi
863:doi
812:doi
808:405
763:doi
704:doi
661:doi
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550:doi
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468:doi
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