Knowledge

Hypogeusia

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While zinc supplementation may treat certain taste dysfunctions, there is a lack of evidence for treatment regarding hypogeusia and dysgeusia not caused by low zinc concentrations in the body. While the mechanisms surrounding hypogeusia from PD are hypothesized, specific treatments are not researched
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When treating oral cancer and related tumors, there is no clear treatment for hypogeusia. Precautions need to be studied and taken to prevent hypogeusia and related symptoms from forming. However, if the treatments have led to the formation of hypogeusia, than patient specific nutrition plans may be
64:, even when many other Covid-19 symptoms are absent. Both can be considered early indications of a Covid-19 infection. Further, hypogeusia is often developed following early symptoms of hyposmia, usually developed from olfactory epithelium damage from upper respiratory infections. 120:
is less well described. PD patients have an increased dysregulation in their taste receptors, as well as their olfactory receptors. The receptors affected in PD patients were those associated with the perception of bitterness in most cases.
100:. Specifically, chemotherapies and radiation treatments may impair or damage various taste related cells, and certain surgeries may even remove minor to major parts of the tongue depending on the severity of the tumor. 27:
and hypogeusia, often classifying them as the same in certain circumstances and studies. The severity of the loss of taste from hypogeusia is not clearly outlined in current research due to these reasons.
116:(CRS) may cause olfactory dysfunction as well as gustatory problems, with either or both leading to the noticeable presence of hypogeusia in CRS patients. The connection between hypogeusia and 152:
enough. Similarly, while treatment of olfactory related issues is known in CRS research, the treatment of gustatory problems, including hypogeusia, are unknown.
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can affect sweet, sour, salty, and bitter tastes, but bitter taste hypogeusia occurs significantly more often compared to the rest of the tastes. Inhibition of
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Xie DX, Leland EM, Seal SM, Lin SY, Rowan NR (March 2021). "A Systematic Review and Meta-Analysis of Taste Dysfunction in Chronic Rhinosinusitis".
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Hypogeusia tied to Covid-19 can serve as an indicator of Covid-19, which can allow appropriate treatments to be administered earlier to patients.
514: 56:. Hypogeusia falls under a neurological disease and a PNS symptom, while also being the highest occurring PNS symptom, closely followed by 19:
can be defined as the reduced ability to taste things. Due to a lack of stratification, the prevalence of hypogeusia, as well as
300: 96:, and surgical treatments, are further causes of taste and smell loss with up to 70% of oral cancer patients noting 509: 49: 430:
Yanagisawa H (March 2008). "Zinc deficiency and clinical practice--validity of zinc preparations".
225:"The prevalence of sensory changes in post-COVID syndrome: A systematic review and meta-analysis" 376:
Togni L, Mascitti M, Vignigni A, Alia S, Sartini D, Barlattani A, et al. (September 2021).
117: 45: 23:, may not be accurately known. Additionally, reviews do not always make distinctions between 85: 8: 60:. Due to hypogeusia being a significant symptom of Covid-19, it is often accompanied by 404: 377: 350: 325: 251: 224: 200: 175: 378:"Treatment-Related Dysgeusia in Oral and Oropharyngeal Cancer: A Comprehensive Review" 485: 447: 409: 355: 306: 296: 256: 205: 93: 191: 477: 439: 399: 389: 345: 337: 288: 246: 236: 195: 187: 109: 53: 341: 292: 113: 503: 324:
Singh S, Meher N, Mohammed A, Razab MK, Bhaskar LV, Nawi NM (February 2023).
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Tarakad A, Jankovic J (2017). "Anosmia and Ageusia in Parkinson's Disease".
489: 451: 413: 359: 310: 260: 209: 89: 88:, is thought of to be the cause of this. Oral cancer treatments, such as 73: 481: 394: 176:"Importance of SARs-Cov-2 anosmia: From phenomenology to neurobiology" 97: 77: 61: 41: 20: 326:"Neurological infection and complications of SARS-CoV-2: A review" 112:
may cause various problems, hypogeusia being one of them. Chronic
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Index

hyposmia
ageusia
Covid-19
central nervous system (CNS)
peripheral nervous system (PNS)
skeletal muscle
anosmia
hyposmia
oral cancer
tumors
gustatory papillae
oropharyngeal tumors
chemotherapy
radiation therapy
dysgeusia
zinc deficiency
Rhinosinusitis
Parkinson's Disease



"Importance of SARs-Cov-2 anosmia: From phenomenology to neurobiology"
doi
10.1016/j.comppsych.2020.152184
PMC
7211704
PMID
32422426
"The prevalence of sensory changes in post-COVID syndrome: A systematic review and meta-analysis"
doi

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