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Makerere University Walter Reed Project

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206:/Marburg vaccine trial, all of which were conducted in accordance with GCP/ICH. Additionally, cohort studies have been conducted in the general population and among most at risk populations to establish HIV prevalence, incidence, risk behavior, cohort retention and host genetics and viral diversity for purposes of vaccine development and future vaccine testing. The vaccine research work is supported by a laboratory located on the Makerere University College of Health Sciences campus. The Lab was accredited by the College of American Pathologists (CAP) in June 2005 and continues to be recertified every two years (most recently until 2013). The lab has the clinical capacity for Safety labs, Diagnostic Serology and Polymerase Chain Reaction (PCR) Viral Load, Immunophenotyping and Peripheral Blood Mononuclear Cell (PBMC) processing, including cryopreservation. The MUWRP laboratory continues to provide training and research opportunities to many students from Ugandan universities and various research organizations throughout the country and also supports external research projects. 119: 185:
Emerging Infections Surveillance and Response System (GEIS) operated by the United States Army Institute of Research – Kenya (USARMR-K) to support Avian Influenza Pandemic Influenza (AIPI) surveillance activities in Uganda. This DoD-GEIS program was established in 1996 to strengthen the prevention of, surveillance of and response to emerging infectious diseases. The current MUWRP program supports surveillance of influenza and other emerging infections in animals and humans and collaborates with the Makerere University College of Veterinary Medicine Animal Resources and Bio-security (COVAB), Ministry of Health, Nature Uganda, CDC, USAID, the MU School of Public Health, St. Jude Children's Hospital, Memphis and the Uganda People's Defence Forces (UPDF).
181:(UVRI) where the focus was development of infrastructure and definition of cohorts. In June 2002 a memorandum of understanding between Makerere University and The Henry M. Jackson Foundation was signed establishing Makerere University Walter Reed Project (MUWRP) as a non-profit partnership for purposes of conducting collaborative HIV and other research studies. Since 1998, collaborative HIV research between Makerere University and the USMHRP has focused on development of infrastructure, definition of cohorts, acquisition of appropriate products for evaluation, and clinical evaluation of these products. The core of the Makerere University Walter Reed Program's effort has been to accomplish all activities required for initiation of phase III trials. 215:
Kayunga district and the recent in-country programming MUWRP's PEPFAR program now includes Mukono and Buvuma districts. Cross-cutting HIV programs include: expanding the number of HIV clinical sites, provision of efficient laboratory capacity, infrastructure remodeling, District-level data system strengthening, supply-chain management strengthening, human capacity development, innovative task shifting, youth-focused and most at risk programs, short-term technical staffing, comprehensive home-based Orphans and Vulnerable Children (OVC) services, and a variety of counseling and testing and prevention programs including medical male circumcision and mother to child prevention.
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collects samples at various locations from water and domestic fowl and swine. The project renovated two BSL laboratories; one at the Uganda Virus Research Institute (UVRI) for the human samples and one at the Makerere University College of Veterinary Medicines Animal Resources and Biosecurity (COVAB) for animal samples. The surveillance activities are part of laboratory based influenza surveillance networks around the world, which serves to:
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by 1) developing evidence-based guidelines for management of clinical syndromes from severe infections; 2) increasing understanding of the pathogenesis and related host-mediated pathways associated with common and/or dangerous infectious agents; and 3) applying the research-based findings to improve outcomes in other less predictable clinical settings (such as an Ebola outbreak in Uganda).
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In 2013 MUWRP agreed to support the Austere environment Consortium for Enhanced Sepsis Outcomes (ACESO). ACESO is composed of collaborators primarily from university, government and military-based institutions within the US and Uganda and aims to improve survival of patients with severe infections
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A key component of these activities has been provision of HIV care including anti-retroviral treatment (ARV) through funding under the PEPFAR Program. Since 2007, MUWRP has broadened their scope of work to address other communicable disease threats as well. In 2007, MUWRP joined with the DoD Global
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MUWRP has established capabilities for influenza surveillance that has since expanded to cover other emerging and re-emerging infectious. The human influenza surveillance is conducted at Mulago, the national referral hospital and Jinja and Gulu regional referral hospitals. The non-human component
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MUWRP has been working in Uganda in the provision of HIV care, treatment, and prevention services since 2005 to ensure sustainable, quality and comprehensive HIV services for communities that have participated or could participate in research studies. Due to the success of the initial program in
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To monitor and investigate communicable disease threats of public health importance to Uganda; and develop, evaluate and provide interventions to mitigate these disease threats.
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College of Health Sciences where the MUWRP laboratory is located. The main facility includes the clinic, administrative, and data offices.
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development and building of vaccine testing capability in Uganda. It is one of the 5 international research sites established by the
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provide isolates for the WHO vaccine pool for vaccine component and 3) detect any emerging strains that could be pandemic potential.
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Physician at Makerere University Walter Reed Project in Uganda discussing the Ebola vaccine
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U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID)
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U.S. Army Medical Research Institute of Chemical Defense (USAMRICD)
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U.S. Army Research Institute of Environmental Medicine (USARIEM)
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United States Army Medical Research Unit- Europe (USAMRU-E)
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Armed Forces Research Institute of Medical Science (AFRIMS)
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MUWRP has conducted a number of HIV vaccine trials and an
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U.S. Army Medical Information Technology Center (USAMITC)
329: 218: 474:"Large Multinational HIV Cohort Study Begins in Africa" 258: 680: 129:was established in 2002 for the primary purpose of 46:. Unsourced material may be challenged and removed. 1756:U.S. Army Center for Environmental Health Research 714:Assistant Secretary of Defense for Health Affairs 575:Makerere University School of Biomedical Sciences 1855: 1782:U.S. Army Medical Research Unit-Kenya (USAMRU-K) 1838:Medical Communications for Combat Casualty Care 1807:List of former United States Army medical units 1787:Makerere University Walter Reed Project (MUWRP) 127:Makerere University Walter Reed Project (MUWRP) 1746:U.S. Army Institute of Surgical Research (ISR) 1731:Walter Reed Army Institute of Research (WRAIR) 570:Makerere University College of Health Sciences 869:U.S. Army Medical Research & Materiel Cmd 580:Makerere University School of Health Sciences 535: 590:Makerere University School of Public Health 443: 441: 542: 528: 709:Surgeon General of the United States Army 351:"Makerere University Walter Reed Project" 261:. Makerere University Walter Reed Project 106:Learn how and when to remove this message 55:"Makerere University Walter Reed Project" 438: 305:"Walter Reed Army Institute of Research" 117: 665:Makerere University Walter Reed Project 549: 253: 251: 249: 247: 245: 1856: 1653:National Museum of Health and Medicine 585:Makerere University School of Medicine 139:Walter Reed Army Institute of Research 1632:U.S. Army School of Aviation Medicine 679: 523: 219:Emerging Infectious Diseases' Program 1679:Walter Reed Tropical Medicine Course 425:"HIV Vaccine Research Collaborators" 242: 177:, Makerere University (MU), and the 148: 44:adding citations to reliable sources 15: 1703:War Surgery in Afghanistan and Iraq 1359:10th Field Hospital (United States) 565:Makerere University Business School 476:. MUWRP. 2013-02-27. Archived from 13: 682:United States Army Medical Command 197: 14: 1880: 1812:United States Army Hospital Corps 1717:Research Institutes & Centers 378:. Hivresearch.org. Archived from 228:detect local influenza outbreaks, 879:U.S. Army Warrior Transition Cmd 722: 616:Mulago Women's Referral Hospital 167:US Military HIV Research Program 20: 491: 466: 401:"Rakai Health Sciences Program" 179:Uganda Virus Research Institute 31:needs additional citations for 1828:Walter Reed Health Care System 393: 368: 343: 322: 297: 272: 1: 1869:2002 establishments in Uganda 1696:Textbook of Military Medicine 998:Medical Department Activities 660:Infectious Diseases Institute 235: 192: 156: 7: 874:U.S. Army Public Health Cmd 693:Category:United States Army 606:Makerere University Library 332:. Chs.mak.ac.ug. 2012-01-13 307:. U.S. Army. Archived from 282:. U.S. Navy. Archived from 161:In May 1998, the Honorable 10: 1885: 802:Major Subordinate Commands 720: 1820: 1799: 1764: 1723: 1716: 1687: 1666: 1645: 1627:AMEDD Center & School 1617: 1610: 1477: 1343: 1250: 1229: 1203: 1194: 1094: 1006: 997: 977: 926: 917: 891: 859:AMEDD Center & School 851: 808: 801: 789:Enlisted medical soldiers 781: 740: 731: 701: 688: 652: 634: 626:University of East Africa 598: 557: 209: 1345:Combat Support Hospitals 773:Medical Specialist Corps 449:"Influenza Surveillance" 175:Johns Hopkins University 1833:Military Vaccine Agency 733:Army Medical Department 643:African Health Sciences 501:. MUWRP. Archived from 451:. MUWRP. Archived from 353:. MUWRP. Archived from 1674:Captains Career Course 1479:Forward Surgical Teams 621:Uganda Heart Institute 123: 768:Medical Service Corps 135:Department of Defense 121: 1394:115th Field Hospital 1117:DiLorenzo TRICARE HC 864:U.S. Army Dental Cmd 40:improve this article 1864:Makerere University 1347:and Field Hospitals 1196:Field medical units 551:Makerere University 171:Columbia University 143:Makerere University 818:North Atlantic RMC 124: 1851: 1850: 1795: 1794: 1712: 1711: 1606: 1605: 1190: 1189: 1142:Heidelberg MEDDAC 993: 992: 908:Forest Glen Annex 887: 886: 797: 796: 673: 672: 149:Mission statement 116: 115: 108: 90: 1876: 1721: 1720: 1637:Borden Institute 1615: 1614: 1252:Medical Brigades 1204:Medical Commands 1201: 1200: 1004: 1003: 924: 923: 899:Fort Sam Houston 828:Great Plains RMC 806: 805: 763:Veterinary Corps 738: 737: 726: 725: 677: 676: 544: 537: 530: 521: 520: 514: 513: 511: 510: 495: 489: 488: 486: 485: 470: 464: 463: 461: 460: 445: 436: 435: 433: 432: 421: 412: 411: 409: 408: 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