118:
29:
106:
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Michikawa Y, Mazzucchelli F, Bresolin N, Scarlato G, Attardi G (October 1999). "Aging-dependent large accumulation of point mutations in the human mtDNA control region for replication".
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linked with the subjects' endurance. It was speculated that this was because the control region affects replication and transcription in the mitochondria.
307:"Population variation of human mtDNA control region sequences detected by enzymatic amplification and sequence-specific oligonucleotide probes"
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are sometimes used synonymously in the literature; specifically the control region includes the D-loop along with adjacent transcription
121:
Location of the control region (CR) in the human mitochondrial genome (grey box), with the three hypervariable regions (HV: green boxes).
448:
Anderson S, Bankier AT, Barrell BG, et al. (April 1981). "Sequence and organization of the human mitochondrial genome".
409:"Evidence for variable selective pressures at a large secondary structure of the human mitochondrial DNA control region"
590:"Polymorphisms in control region of mtDNA relates to individual differences in endurance capacity or trainability"
750:
499:
Ojala D, Montoya J, Attardi G (April 1981). "tRNA punctuation model of RNA processing in human mitochondria".
351:"Human Mitochondrial DNA Variation and Evolution: Analysis of Nucleotide Sequences from Seven Individuals"
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678:"A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms"
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the control region of 55 subjects and compared their haplotype with the increase in
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Stoneking M, Hedgecock D, Higuchi RG, Vigilant L, Erlich HA (February 1991).
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635:"Hypervariable Sites in the mtDNA Control Region Are Mutational Hotspots"
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Sachidanandam R, Weissman D, Schmidt SC, et al. (February 2001).
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Murakami H, Ota A, Simojo H, Okada M, Ajisaka R, Kuno S (June 2002).
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region of the human mtDNA genome, with polymorphism concentrated in
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Pereira F, Soares P, Carneiro J, et al. (December 2008).
137:. This region controls RNA and DNA synthesis. It is the most
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208:. For this reason, the control region is also known by the
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in these regions is 1.7%. Despite this variability, an
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Mitochondrial DNA control region secondary structure A
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295:DNA Learning Center, Cold Spring Harbor Laboratory
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721:- the Mitochondrial DNA Control Region Database
256:. They found that different haplotypes were
153:transcript from this region has a conserved
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188:but not in mice or cows, where it has been
349:Aquadro CF, Greenberg BD (February 1983).
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27:
16:Non-coding region of the mitochondrial DNA
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240:capacity in human subjects. A 2002 study
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293:Structure of the Mitochondrial Genome
168:The mtDNA control region contains the
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176:for both strands. There is also an
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172:of one strand, and the origin of
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200:The control region and mtDNA
633:Stoneking M (October 2000).
564:10.1126/science.286.5440.774
41:of the mtDNA control region.
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196:Distinction from D-loop
180:thought to code for 7s
751:Mitochondrial genetics
236:have been linked with
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426:10.1093/molbev/msn225
232:mtDNA control region
170:origin of replication
143:hypervariable regions
120:
275:Hypervariable region
252:after an eight-week
147:nucleotide diversity
131:mitochondrial genome
127:mtDNA control region
513:1981Natur.290..470O
462:1981Natur.290..457A
220:oop and associated
155:secondary structure
35:secondary structure
212:DLP, standing for
178:open reading frame
163:selective pressure
129:is an area of the
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639:Am. J. Hum. Genet
311:Am. J. Hum. Genet
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688:(6822): 928–33.
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558:(5440): 774–9.
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507:(5806): 470–4.
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419:(12): 2759–70.
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145:. The average
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139:polymorphic
47:Identifiers
740:Categories
390:2010-07-29
281:References
234:haplotypes
224:romoters.
103:structures
72:Other data
39:haplotypes
242:sequenced
238:endurance
133:which is
89:Domain(s)
55:mtDNA ssA
704:11237013
669:10968778
616:12230801
572:10531063
435:18845547
355:Genetics
264:See also
159:pictured
94:Mammalia
37:for all
660:1287875
552:Science
537:4323371
529:7219536
509:Bibcode
486:4355527
478:7219534
458:Bibcode
385:6299878
376:1219980
333:1990843
324:1683035
210:acronym
190:deleted
66:RF01853
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682:Nature
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501:Nature
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450:Nature
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270:D-loop
202:D-loop
186:humans
52:Symbol
719:EMPOP
533:S2CID
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731:Rfam
700:PMID
665:PMID
612:PMID
568:PMID
525:PMID
474:PMID
431:PMID
381:PMID
329:PMID
125:The
107:PDBe
80:type
61:Rfam
746:DNA
729:at
690:doi
686:409
655:PMC
647:doi
602:doi
560:doi
556:286
517:doi
505:290
466:doi
454:290
421:doi
371:PMC
363:doi
359:103
319:PMC
250:max
184:in
151:RNA
101:PDB
78:RNA
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