47:
38:
269:
been served in school-lunch programs. Starting in 2010, PATH distributed Ultra Rice to
Cambodia through food assistance programs and for further research, for which it now has over thirty studies. The results showed that fortified rice was well accepted by children, parents and teachers and consumption of it was similar or better than normal rice. In 2012, PATH entered a
229:, a small sticker that adheres to a vaccine vial and changes color as the vaccine is exposed to heat over time. The sticker shows when a vaccine has reached its preset temperature limit and can no longer be safely used. It took over thirty years until 2007 for the widespread adoption of this technology by vaccine manufacturers.
308:
designed to be easier to use effectively, less noisy and more comfortable other female condoms. PATH transferred production of the condom to Dahua
Medical Apparatus Company in China in 2008. The condom has received regulatory approvals in China and the European Union and became commercially available
478:
techniques to encourage healthy behaviors for HIV prevention. One of the best-known examples is PATH's work with "magnet theater" in Kenya, India, Vietnam, and other developing countries. Named because of its natural pulling power, this interactive street theater draws people in rural communities to
293:
as the first molecular diagnostic to screen for human papillomavirus (HPV)—the most common cause of cervical cancer—in clinics in low-resource settings. China's State Food and Drug
Administration approved the test for sale beginning in January 2013, followed by India and other emerging markets. The
268:
and iron, and it is capable of reducing the incidence of anemia and infant (6-24 month old) mortality in low-income populations. It is typically mixed with regular rice at a 1:100 ratio. Ultra Rice has been produced and tested in several countries, including Brazil, Burundi, and India, where it has
240:
injection system. The single-dose, autodisabling injection system consists of a needle attached to a small bubble of plastic that is prefilled with medication. The system is designed to prevent disease transmission and requires low training to administer vaccine and other drugs safely, intended for
457:
that will bolster the current, volatile botanical supply. In August 2014, PATH and Sanofi announced the release of the first batch of semisynthetic artemisinin. 1.7 million doses of Sanofi's ArteSunate AmodiaQuine
Winthrop (ASAQ Winthrop), a fixed-dose artemisinin-based combination therapy will be
423:
for young children ages 5 to 17 months, and another 2012 study showed a 33 percent reduction in infants. In
October 2013, GlaxoSmithKline reported that the experimental vaccine reduced the number of cases amongst young children by almost 50 percent and among infants by around 25 percent, following
318:
PATH looks at ways to improve water quality in developing countries, including helping companies develop low-cost filters, gadgets, and other water-treatment products to stimulate a commercial market and keep prices low. Most recently, PATH partnered with Splash! to develop and test a handwashing
495:
focused on safe birth for mothers and babies. PATH worked with local governments and community groups to encourage community leaders, health workers, pregnant women, and families to deliver babies in health centers, rather than at home, and adopt other best practices to protect mothers and their
466:
PATH works in Africa, Asia, and other regions to slow the spread of HIV/AIDS and provide support for people affected by the disease. For example, in Kenya, PATH has conducted over two decades of research into HIV and pregnancy prevention. PATH also provides support groups and health services for
379:
PATH supports the introduction of vaccines against rotavirus in developing countries to protect young children from severe diarrhea. In 2006, PATH helped
Nicaragua become the first developing country to introduce rotavirus vaccines within months of their introduction. Former PATH researcher John
363:
and introduced in
Burkina Faso, Mali, and Niger in December 2010 to prevent the spread of a strain of meningitis found only in Africa. Within six months, the vaccine eliminated new cases of meningitis A in the areas where it was introduced. By the end of 2012, the vaccine had reached 100 million
156:
with 1,600 employees in more than 70 countries around the world. Its president and CEO is
Nikolaj Gilbert, who is also the Managing Director and CEO of Foundations for Appropriate Technologies in Health (FATH), PATH's Swiss subsidiary. PATH focuses on six platforms: vaccines, drugs, diagnostics,
301:, a "one size fits most" contraceptive device. The device differs from traditional latex diaphragms in that it is made of silicone instead of latex, is designed to hold up to extreme temperatures and poor storage conditions common in developing countries, and will not require a doctor's fitting.
367:
Previously used meningitis vaccines had low efficacy and cost USD $ 80 per dose. The new vaccine has high efficacy against the type of meningitis that is most prevalent in Africa and costs less than $ 0.50 per dose. The entire vaccination research and development project cost less than US$ 100
479:
clearings, dirt roads, and village centers—any open space where people can gather. There, actors banter with their audiences and pull them into the play, stimulating dialogue about HIV/AIDS and other taboo subjects and helping individuals re-examine behaviors that contribute to poor health.
395:—a disease the World Health Organization estimates claims 10,000 to 15,000 lives a year, mostly children, and causes permanent brain damage in many more. In 2006, PATH helped the government of India launch an immunization campaign for children in high-risk areas with the vaccine.
487:
In addition to its work on vaccines for childhood illnesses, PATH addresses pregnancy complications, nutrition issues, and other health challenges that affect women and children in developing countries and lead to higher rates of illness and death.
439:, indoor spraying of insecticides, new diagnostic tools to find infection, and effective medicines for treatment. In Zambia, this work has helped decrease the rate of malaria among children younger than age 5 by 50 percent in two years.
364:
people in ten countries: Benin, Burkina Faso, Cameroon, Chad, Ghana, Mali, Niger, Nigeria, Senegal, and Sudan. The introduction of MenAfriVac marked the first time that a vaccine was developed for a disease only found in Africa.
467:
married adolescents and other groups at high risk for HIV. It also liases with local governments and community organizations to strengthen and expand services for HIV/AIDS, malaria, tuberculosis, and maternal and newborn health.
767:
1454:
1634:
470:
Other PATH projects to address HIV in Africa include improving access to HIV treatment and services in
Ethiopia and expanding HIV counseling and testing and other services in the Democratic Republic of Congo.
534:
In 2012, the NGO was warned by the Indian government after one of its studies involving an HPV vaccine resulted in the alleged death of seven girls belonging to an indigenous community (tribe) in India.
1223:
832:
371:
In 2012, MenAfriVac was also approved for storage without refrigeration for up to four days, enabling health workers to more easily reach patients in rural villages or in areas with no power.
2368:
523:
PATH's income in 2020 was $ 303,223,000 and its expenses in 2020 were US$ 294,369,000. 86.4% of its budget was spent on program activities, 12.8% on administration, and .8% on fundraising.
435:
Another PATH initiative to address malaria is the
Malaria Control and Evaluation Partnership in Africa (MACEPA), which focuses on controlling malaria through the use of insecticide-treated
694:
1519:
1446:
1607:
1254:
1778:
411:
The PATH Malaria Vaccine Initiative supports several malaria vaccine candidates at various stages of development around the world, including the most advanced candidate, called
1864:
1747:
1043:
17:
2245:
1630:
2373:
995:
743:
419:, in phase 3 clinical trials among infants and young children in sub-Saharan Africa. A 2011 study showed the vaccine provided about 50 percent protection against
2343:
446:
for a new malaria project focused on "the expansion of high-quality diagnosis and treatment for malaria and other childhood illnesses and infectious diseases."
383:
PATH also conducts research to show the impact of rotavirus vaccines and help countries choose whether to adopt the vaccines into their immunization programs.
1215:
526:
In 2010, PATH received the most US foundation grants in the state of Washington and ranked thirteenth among international recipients of US foundation grants.
824:
2135:
1485:
1334:
2348:
1365:
359:
to end meningitis A epidemics in sub-Saharan Africa, where 450 million people in 26 countries are at risk of the disease. The vaccine was developed by
1018:
538:
All 7 deaths were later attributed to other causes, including a snake bite, drowning, suicide by pesticide ingestion, and complications from malaria.
664:
327:
Starting in 2010, PATH has collaborated with biotechnology and pharmaceutical companies to support the development of vaccines for diseases such as
1081:
961:
911:
2238:
1812:
1834:
863:
208:
In 2000, PATH had 300 employees and an annual budget of $ 60 million. In 2020, this increased to 1,600 employees and a budget of $ 323 million.
2363:
2338:
690:
380:
Wecker noted that rotavirus infections dropped in areas that began to use the vaccine after the WHO recommended its international use in 2009.
173:, PATH soon broadened its purpose to work on a wide array of emerging and persistent global health issues in the areas of health technologies,
2017:
403:
Part of PATH's work focuses on some of the most widespread and threatening global diseases: malaria, HIV/AIDS, tuberculosis, and influenza.
1599:
1246:
1187:
1968:
1511:
2200:
2193:
2186:
2172:
2165:
2158:
801:
2353:
2231:
2075:
1108:
1939:
1909:
1875:
1541:
1161:
1755:
1413:
264:
grain that can be mixed with rice to reduce malnutrition in countries where rice is a staple food. The micronutrients include zinc,
1995:
547:
called "a shockingly unethical trial", nearly 2,800 consent forms were signed by a hostel warden or headmaster, as the 'guardian'.
2358:
1051:
2048:
619:
424:
the conclusion of an 18-month clinical trial. GlaxoSmithKline is set to submit an application for a marketing license with the
511:, PATH leads a five-year project to improve the health and development of 750,000 pregnant women and children by encouraging
1665:
1717:
987:
583:
496:
infants during pregnancy, childbirth, and infancy. The project used community outreach approaches including door-to-door
1388:
1572:
559:'s Dr. Alejandro Zaffaroni Health Award for its work on the Uniject device, a sterile pre-filled, single-use syringe.
2101:
443:
1687:
2179:
885:
2131:
2223:
1477:
1326:
1357:
556:
475:
1842:
391:
PATH works in India and other countries in the region to introduce an affordable vaccine to protect against
432:
which states that it will recommend the use of RTS,S for use starting in 2015, providing it gets approval.
653:
273:
in Brazil with a commercial rice producer to sell Ultra Rice mixed in with regular rice at supermarkets.
2286:
1695:
1073:
1804:
855:
425:
352:
222:
935:
2025:
360:
253:
is a manufactured grain owned by PATH. Designed to resemble the texture and appearance of regular
576:
571:
1960:
1423:
719:
589:
In 2012, PATH was ranked as the sixth best NGO in the world on the "top 100" list published by
294:
test is designed specifically for use in clinics that lack reliable clean water or electricity.
2079:
912:"'Ultra Rice' slips nutrients in via one special grain for every 100 ordinary grains of rice"
793:
497:
392:
340:
1931:
1901:
1549:
226:
8:
178:
1991:
1302:
1277:
614:
590:
261:
2269:
1631:"Sanofi shipping new malaria treatment manufactured from 'semisynthetic artemisinin'"
1307:
2052:
1247:"Africa: A Change in Guidelines Could Extend a Vaccine's Reach in 'Meningitis Belt'"
1297:
1289:
1162:"Dr. Besser's Notebook: New Meningitis Shot Protects Hearing in Africa's Children"
744:"Vaccine Vial Monitors: "The Little Big Thing:" Taking Social Innovation to Scale"
355:, through the Meningitis Vaccine Project, led the development of a vaccine called
2312:
2202:
Pharmaceutical and Biomedical Project Management in a Changing Global Environment
1657:
1134:
450:
416:
298:
174:
170:
2253:
825:"Seattle nonprofit PATH set to launch 'Ultra Rice' to fight global malnutrition"
1865:"Top 50 recipients of foundation grants in the state of Washington, circa 2010"
1576:
501:
46:
1725:
2332:
629:
624:
512:
319:
station for use in LMICs, specifically in response to the COVID-19 pandemic.
305:
258:
1311:
1192:
609:
597:
508:
436:
198:
186:
2109:
1293:
596:
As of March 2019, PATH has been vetted and is in good standing as part of
454:
335:
and to help countries introduce vaccines for childhood illnesses such as
270:
2317:
2302:
1216:"Africa's Meningitis Belt Gets First Vaccine Designed For Poor Nations"
634:
449:
PATH's Drug Development program, which grew out of an affiliation with
428:(EMA) in 2014. The new vaccine has the backing of the UN's Swiss-based
356:
328:
265:
250:
167:
Program for the Introduction and Adaptation of Contraceptive Technology
1992:"Annual Tech Museum Awards Grant $ 250,000 to Five Global Innovators"
1418:
1135:"Africa: 100 Millionth Person Receives Lifesaving Meningitis Vaccine"
543:
336:
332:
149:
458:
shipped to half a dozen African countries over the next few months.
368:
million, about one-fifth the typical cost for developing a vaccine.
962:"China's SFDA approves QIAGEN careHPV Test and instrument platform"
202:
1564:
1542:"New Malaria Diagnosis and Treatment Project Awarded: MalariaCare"
281:
PATH technologies address sexual and reproductive health include:
37:
2307:
515:
and improving health care for pregnant women and young children.
420:
237:
194:
182:
153:
86:
563:
290:
230:
1779:"Street theater aims to get folks talking about health issues"
492:
453:, is advancing a new, semisynthetic form of the malaria drug
412:
2369:
Medical and health organizations based in Washington (state)
1932:"Is Bill Gates Being Sued by India Over Vaccination Deaths?"
856:"Ultra Rice: Whatcom County invention holds hope for health"
254:
1278:"New vaccines to boost child care in developing countries"
688:
216:
682:
429:
190:
1600:"Bio-Tech Breakthrough Could End Malaria Drug Shortages"
1188:"New Meningitis Vaccine Could be Model for Future Drugs"
691:"PATH, influential global health office, marks 30 years"
566:' top 200 list of the 200 largest charities in America.
2257:(formerly Program for Appropriate Technology in Health)
2073:
1044:"Woman's Condom: Expanding Options for Dual Protection"
128:
2216:
1358:"Diarrhea vaccines could save 2 million lives: report"
504:
to spread messages about maternal and newborn health.
233:
requires these monitors on all vaccines it purchases.
442:
In December 2012, PATH received an award from the US
2195:
Bioproperty, Biomedicine and Deliberative Governance
2049:"45 Social Entrepreneurs Who Are Changing the World"
1512:"PATH leader: Fight against malaria making progress"
1109:"Cheap vaccine eradicates new cases of meningitis A"
1019:"Coming soon: An improved, noiseless female condom"
2188:Novick & Morrow's Public Health Administration
1989:
1478:"GSK aims to market world's first malaria vaccine"
1414:"Immunisation drive against Japanese encephalitis"
1107:
1327:"Studies show swift impact of rotavirus vaccines"
276:
2374:Medical research institutes in the United States
2330:
500:, distribution of printed health materials, and
491:In 2012, PATH completed a seven-year project in
1835:"SA maternal and child death unacceptably high"
1688:"KENYA: HIV prevention for married adolescents"
886:"Ultra Rice: A boost for malnourished children"
768:"WHO, UNICEF urge use of vaccine vial monitors"
2344:International medical and health organizations
2167:OECD Studies on SMEs and Entrepreneurship SMEs
575:magazine in 2008 named PATH as one of the top
2239:
1505:
1503:
1475:
189:, and emerging and epidemic diseases such as
152:global health organization. PATH is based in
1628:
482:
322:
146:Program for Appropriate Technology in Health
18:Program for Appropriate Technology in Health
689:Seattle Post-Intelligencer (May 21, 2007).
2246:
2232:
2160:An Introduction to Social Entrepreneurship
2132:"Charity Navigator — Rating for PATH"
1500:
1101:
1099:
157:devices, system, and service innovations.
36:
2349:Non-profit organizations based in Seattle
1953:
1893:
1658:"Kenya: The Power to Protect and to Plan"
1389:"India Launches Encephalitis Vaccination"
1301:
1282:Bulletin of the World Health Organization
822:
211:
2046:
794:"Health innovations in poorer countries"
386:
1776:
1770:
1656:Mwololo, Millicent (30 November 2011).
1655:
1324:
1159:
1105:
1096:
1016:
518:
313:
217:Vaccine and pharmaceutical technologies
14:
2331:
2174:The Search for Social Entrepreneurship
1802:
1597:
1509:
1244:
1185:
620:Reproductive Health Supplies Coalition
249:Developed by Bon Dente International,
2364:Charities based in Washington (state)
2339:Health charities in the United States
2227:
1912:from the original on 13 November 2012
1610:from the original on 18 February 2013
1444:
1386:
1275:
1257:from the original on 12 December 2012
1084:from the original on 11 February 2014
415:. Researchers studied RTS,S, made by
1748:"PATH secures major HIV/AIDS grants"
1573:"From ancient China to a modern lab"
1510:Bauman, Valerie (21 November 2012).
1488:from the original on 18 January 2016
1337:from the original on 18 January 2016
1213:
866:from the original on 21 October 2012
853:
835:from the original on 8 December 2012
804:from the original on 14 October 2012
748:Stanford Graduate School of Business
714:
712:
398:
289:test, developed in conjunction with
2024:. November 24, 2009. Archived from
1998:from the original on March 11, 2010
1899:
1668:from the original on 3 January 2012
1637:from the original on 26 August 2014
1447:"Tests find malaria vaccine useful"
1355:
1245:McNeil, Donald (19 November 2012).
998:from the original on 12 August 2014
936:"Urbano vai produzir ' Ultra Rice'"
584:Conrad N. Hilton Humanitarian Prize
24:
2152:
1971:from the original on 19 April 2012
1841:. 9 September 2012. Archived from
1457:from the original on 22 April 2014
1226:from the original on 22 April 2014
823:Timmerman, Luke (13 August 2008).
697:from the original on June 27, 2021
670:from the original on July 14, 2021
98:Nikolaj Gilbert, President and CEO
25:
2385:
2354:Organizations established in 1977
2208:
1815:from the original on 30 June 2012
1698:from the original on 12 July 2024
1633:. fiercepharmamanufacturing.com.
1598:Miller, Talea (31 October 2011).
1522:from the original on 12 July 2024
1325:Kelland, Kate (20 January 2011).
1214:Knox, Richard (6 December 2010).
1186:Miller, Talea (6 December 2010).
909:
709:
562:Since 2005, PATH has remained on
1570:
1476:Kelland, Kate (7 October 2013).
1445:Brown, David (9 November 2012).
1160:Richard, Besser (8 March 2011).
1017:Nakkazi, Esther (24 July 2011).
529:
225:starting in 1979 to develop the
45:
2138:from the original on 2020-09-26
2124:
2094:
2076:"Humanitarian Prize Recipients"
2067:
2040:
2010:
1983:
1942:from the original on 2024-07-12
1924:
1857:
1827:
1803:Vrinda, Malik (26 April 2012).
1796:
1754:. 23 April 2009. Archived from
1740:
1710:
1680:
1649:
1629:Palmer, Eric (19 August 2014).
1622:
1591:
1534:
1469:
1438:
1406:
1380:
1368:from the original on 2016-01-18
1349:
1318:
1269:
1238:
1207:
1179:
1153:
1127:
1066:
1036:
1010:
980:
954:
928:
903:
2359:Research institutes in Seattle
1900:The, Hindu (August 25, 2012).
1777:Davidow, Julie (23 May 2005).
1422:. 26 July 2006. Archived from
1387:Mason, Margie (26 July 2006).
1106:Coghlan, Andy (14 June 2011).
878:
847:
816:
786:
760:
736:
646:
550:
444:President's Malaria Initiative
277:Sexual and reproductive health
13:
1:
2074:Conrad N. Hilton Foundation.
1074:"Taking on third world water"
988:"The Future of Birth Control"
854:Heim, Kristi (24 July 2010).
640:
476:behavior change communication
346:
1902:"Hindu report on HPV trials"
1516:Puget Sound Business Journal
579:who are changing the world.
374:
244:
7:
603:
582:In 2009, PATH received the
555:In 2003, PATH received the
461:
221:PATH collaborated with the
70:; 47 years ago
10:
2390:
2287:Meningitis Vaccine Project
1783:Seattle Post-Intelligencer
1356:Fox, Maggie (2010-01-27).
406:
160:
2295:
2279:
2262:
1718:"APHIAplus–Western Kenya"
1276:Parry, Jane (June 2007).
654:"PATH 2020 Annual Report"
483:Maternal and child health
426:European Medicines Agency
353:World Health Organization
323:Vaccines and immunization
223:World Health Organization
123:
113:
102:
92:
82:
64:
56:
44:
35:
2018:"PATH — Forbes.com"
1990:The Tech Museum Awards.
569:For five years running,
361:Serum Institute of India
236:PATH also developed the
2102:"The Top 100 NGOs 2012"
772:Infectious Disease News
600:'s GG Rewards program.
165:Founded in 1977 as the
148:) is an international,
144:(formerly known as the
51:Headquarters in Seattle
27:Global health nonprofit
2108:. 2012. Archived from
1575:. PATH. Archived from
309:in China in late 2011.
304:The Woman's Condom, a
212:Developed technologies
60:Nonprofit organization
2134:. Charity Navigator.
2082:on September 14, 2005
2055:on September 16, 2008
1961:"The Hindu Editorial"
1872:The Foundation Center
1839:MSN South Africa News
1805:"The snowball effect"
1294:10.2471/BLT.07.020607
1048:Women Deliver website
498:clinical surveillance
393:Japanese encephalitis
387:Japanese encephalitis
341:Japanese encephalitis
2028:on November 29, 2009
890:World Vision website
577:social entrepreneurs
519:Funding and expenses
314:Water and sanitation
271:business partnership
227:vaccine vial monitor
1881:on 10 February 2013
1728:on 20 February 2013
1722:USAID Kenya website
1694:. 15 October 2010.
1552:on 14 February 2013
1451:The Washington Post
1393:The Washington Post
1080:. 9 December 2006.
1054:on 20 November 2012
179:reproductive health
115:Number of employees
32:
2106:The Global Journal
1579:on 9 February 2014
1251:The New York Times
994:. 6 January 2011.
968:. 29 November 2012
942:. 23 February 2012
615:Concept Foundation
591:The Global Journal
30:
2326:
2325:
2270:Christopher Elias
1938:. 10 April 2020.
1752:The Seattle Times
1141:. 3 December 2012
1078:The Seattle Times
916:phnompenhpost.com
860:The Seattle Times
399:Epidemic diseases
241:remote villages.
139:
138:
16:(Redirected from
2381:
2248:
2241:
2234:
2225:
2224:
2220:
2219:
2217:Official website
2147:
2146:
2144:
2143:
2128:
2122:
2121:
2119:
2117:
2112:on 26 March 2013
2098:
2092:
2091:
2089:
2087:
2078:. Archived from
2071:
2065:
2064:
2062:
2060:
2051:. Archived from
2044:
2038:
2037:
2035:
2033:
2014:
2008:
2007:
2005:
2003:
1987:
1981:
1980:
1978:
1976:
1967:. May 15, 2011.
1957:
1951:
1950:
1948:
1947:
1928:
1922:
1921:
1919:
1917:
1897:
1891:
1890:
1888:
1886:
1880:
1874:. Archived from
1869:
1861:
1855:
1854:
1852:
1850:
1845:on 11 April 2013
1831:
1825:
1824:
1822:
1820:
1800:
1794:
1793:
1791:
1789:
1774:
1768:
1767:
1765:
1763:
1758:on 24 April 2014
1744:
1738:
1737:
1735:
1733:
1724:. Archived from
1714:
1708:
1707:
1705:
1703:
1684:
1678:
1677:
1675:
1673:
1653:
1647:
1646:
1644:
1642:
1626:
1620:
1619:
1617:
1615:
1595:
1589:
1588:
1586:
1584:
1568:
1562:
1561:
1559:
1557:
1548:. Archived from
1538:
1532:
1531:
1529:
1527:
1507:
1498:
1497:
1495:
1493:
1473:
1467:
1466:
1464:
1462:
1442:
1436:
1435:
1433:
1431:
1426:on 11 April 2013
1410:
1404:
1403:
1401:
1399:
1384:
1378:
1377:
1375:
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1347:
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1267:
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1204:
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1172:
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1131:
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1124:
1122:
1120:
1111:
1103:
1094:
1093:
1091:
1089:
1070:
1064:
1063:
1061:
1059:
1050:. Archived from
1040:
1034:
1033:
1031:
1029:
1023:The East African
1014:
1008:
1007:
1005:
1003:
984:
978:
977:
975:
973:
958:
952:
951:
949:
947:
932:
926:
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923:
922:
907:
901:
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898:
896:
882:
876:
875:
873:
871:
851:
845:
844:
842:
840:
820:
814:
813:
811:
809:
800:. 16 July 2007.
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557:Tech Museum
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2263:Key people
2142:2019-12-21
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