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Salivary gland tumour

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243: 718:- Due to the poor results with chemotherapy, it's urgent to explore novel therapeutic interventions for this disease. And great expectations have been put into individualized therapies: in particular, the EGF receptors family (EGFR and HER2), KIT and androgen receptors are the most commonly investigated molecular targets in SGCs. Their expression seems not to be linked to its pathogenetic role in the development of SGCs, but more to the histogenetic origin of the tumor cells. Various targeted agents, such as imatinib, cetuximab, gefitinib, trastuzumab, had been used for exploring new treatment for salivary gland tumours, but on account of the rare incidence of salivary gland tumours, the number of cases available on targeted therapy for analysis is relatively small. 313: 657: 305: 332: 24: 133: 1507: 3884: 295:
Ultrasound can be used to initially assess a tumour that is located superficially in either the submandibular or parotid gland. It can distinguish an intrinsic from an extrinsic neoplasm. Ultrasonic images of malignant tumours include ill-defined margins. Furthermore, high resolution ultrasound can
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Little is known about the total incidence of salivary gland tumours as most benign tumours go unrecorded in national cancer registries. The majority of salivary tumours are benign (65-70%). Within the parotid gland 75 - 80% of tumours are benign. Around 50% of the tumours found in the submandibular
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Most patients with early-stage lesions that are resectable generally tend to undergo surgery as their initial therapeutic approach, whereas those with advanced or unresectable cancers tend to be treated with radiotherapy (RT) alone or chemoradiotherapy (CRT), which hampered the comparison of the
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Currently little is known about the efficacy of chemotherapy in treating salivary gland tumours. Chemotherapy, which plays an important role in systemic therapy, is generally reserved for the palliative treatment of symptomatic locally recurrent and/or metastatic disease that is not amenable to
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Laramore GE, Krall JM, Griffin TW, Duncan W, Richter MP, Saroja KR, Maor MH, Davis LW (September 1993). "Neutron versus photon irradiation for unresectable salivary gland tumors: final report of an RTOG-MRC randomized clinical trial. Radiation Therapy Oncology Group. Medical Research Council".
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Benign tumour of the submandibular gland, also known as pleomorphic adenoma, presented as a painless neck mass in a 40-year-old man. At the left of the image is the white tumor with its characteristic cartilaginous cut surface. To the right is the normally lobated submandibular salivary
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glands are benign. Sublingual gland tumours are very rare but if present, they are most likely to be malignant. Saku et al. in 1997 and Venturi in 2021, reported the causal role for ionizing radiation in salivary gland tumorigenesis, particularly for mucoepidermoid carcinoma.
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A procedure to look at organs and tissues inside the body to check for abnormal areas. For salivary gland cancer, an endoscope is inserted into the mouth to look at the mouth, throat, and larynx. An endoscope is a thin, tube-like instrument with a light and a lens for viewing.
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An exam of the body to check general signs of health. The head, neck, mouth, and throat will be checked for signs of disease, such as lumps or anything else that seems unusual. A history of the patient's health habits and past illnesses and treatments will also be taken.
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Venturi, S. | Correlation of Diabetes, Salivary gland cancer and Pancreatic Cancer with Iodine and Cesium Radionuclides| Researchgate | December| 2022 | https:// www.researchgate.net/profile/Sebastiano-Venturi-4/publication/366530240
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The removal of tissue or fluid using a thin needle. An FNA is the most common type of biopsy used for salivary gland cancer and has been shown to produce accurate results when differentiating between benign and malignant tumours.
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further surgery or radiation. Conventional chemotherapy regimens, such as cisplatin and 5-FU or CAP (cisplatin, doxorubicin, and cyclophosphamide) are still utilized as first-line therapy for patients with advanced lesions.
3821: 3798: 218:). Usually, in their early stages, it is not possible to distinguish a benign tumour from a malignant one. One of the key differentiating symptoms of malignant growth is nerve involvement; for example, signs of 213:
Salivary gland tumours usually present as a lump or swelling in the affected gland which may or may not have been present for a long time. The lump may be accompanied by symptoms of duct blockage (e.g.
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Complete surgical resection, with adequate free margins, is currently the mainstay treatment for salivary gland tumours. However elective treatment of the N0 neck region remains a controversial topic
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in 2005, which classifies salivary neoplasms as primary or secondary, benign or malignant, and also by tissue of origin. This system defines five broad categories of salivary gland neoplasms:
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are also very often associated with malignant tumours. Other red flag symptoms which may suggest malignancy and warrant further investigation are fixation of the lump to the overlying skin,
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Saku T, Hayashi Y, Takahara O, Matsuura H, Tokunaga M, Tokunaga M, Tokuoka S, Soda M, Mabuchi K, Land CE (1997). "Salivary gland tumors among atomic bomb survivors, 1950-1987".
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has been used successfully to treat salivary gland tumors, and has shown to be significantly more effective than photons in studies treating unresectable salivary gland tumors.
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Krüll A, Schwarz R, Engenhart R, Huber P, Lessel A, Koppe H, Favre A, Breteau N, Auberger T (1996). "European results in neutron therapy of malignant salivary gland tumors".
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on 24 October 1785. The tumour weighed over 4 kilograms and took twenty-five minutes to remove. The specimen currently resides in the Hunterian Museum at the
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efficacy of RT alone with that of surgery combined with adjuvant RT. But some effort had been made to reflect the role of surgery in salivary gland tumours.
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Many diagnostic methods can be used to determine the type of salivary gland tumour and if it is benign or malignant. Examples of diagnostic methods include:
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An OPG (orthopantomogram) can be taken to rule out mandibular involvement. A chest radiograph may also be taken to rule out any secondary tumours.
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identify the exact tumour location within the parotid gland, its relationship to the retromandibular vein and assist surgical excision.
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glands. The minor salivary glands consist of 800 to 1000 small mucus-secreting glands located throughout the lining of the
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In the United States, salivary gland cancers are uncommon with an incidence rate of 1.7 in 100000 between 2009 and 2013.
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The removal of cells or tissues so they can be viewed under a microscope by a pathologist to check for signs of cancer.
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Psychogios, Georgios; Rueger, Holger; Jering, Monika; Tsoures, Eleni; Künzel, Julian; Zenk, Johannes (September 2019).
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These tests can confirm the presence of a tumour. An MRI or CT Scan can also show whether metastasis has occurred.
158: 56: 3287: 2924: 2378: 3554: 3899: 3272: 3107: 1355:"Expression of KIT (CD117) in neoplasms of the head and neck: an ancillary marker for adenoid cystic carcinoma" 154: 45: 3112: 581: 2975: 2636: 2245: 1949: 1934: 1872: 1818: 1741: 1559: 1394: 1165: 1166:"Chapter 5: Tumors of the salivary glands (chapter authors: Eveson JW, Auclair P, Gnepp DR, El-Naggar AK)" 3164: 3127: 2857: 2138: 2050: 990:
Vaishali H Anand et al. FNAC and Histopathology of Salivary Gland Tumors. SEAJCRR. 2014 Feb 3(1):609-618
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Lee YY, Wong KT, King AD, Ahuja AT (June 2008). "Imaging of salivary gland tumours".
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Mehanna, Hisham; McQueen, Andrew; Robinson, Max; Paleri, Vinidh (23 October 2012).
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10.1002/1097-0142(19831201)52:11<2007::AID-CNCR2820521106>3.0.CO;2-T
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10.1002/(SICI)1097-0142(19970415)79:8<1465::AID-CNCR4>3.0.CO;2-A
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If a salivary gland tumour is cancerous, Radiation Therapy may be necessary
690: 597: 376: 219: 3413: 1440: 1395:"About salivary gland cancer | Salivary gland cancer | Cancer Research UK" 1331: 1290: 1259: 3864: 3739: 3734: 3726: 3609: 3593: 3471: 3461: 3451: 3368: 3363: 3294: 2368: 2329: 2148: 2024: 1984: 1852: 1773: 1753: 425: 227: 202: 3790: 3712: 3431: 3217: 3043: 2811: 2641: 2582: 2520: 2510: 2503: 2498: 2436: 2419: 2363: 2334: 2255: 2116: 2094: 1979: 1959: 564: 366: 215: 1198:"Treatment of salivary gland neoplasms with fast neutron radiotherapy" 1071: 907: 3299: 3282: 3018: 2796: 2599: 2223: 2106: 1726: 1621: 1599: 1535:
Cancer Facts and Figures 2017, Special Section: Rare Cancer in Adults
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Creagan, ET; Woods, JE; Schutt, AJ; O'Fallon, JR (1 December 1983).
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Douglas JG, Koh WJ, Austin-Seymour M, Laramore GE (September 2003).
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Zaleski, Michael P.; Kalhor, Neda; Moran, Cesar A. (November 2020).
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cavity. Patients with these types of tumours may be asymptomatic.
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International Journal of Environmental Research and Public Health
1143:. Vol. 1 (3rd ed.). Taylor & Francis. p. 511. 682: 226:) are associated with malignant parotid tumours. Facial pain and 190: 174: 132: 1195: 3802: 3137: 2609: 2197: 1792: 604:
Others, not included in the WHO classification above, include:
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Text was copied from this source, which is available under a
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Coronal MRI showing right parotid adenoid cystic carcinoma.
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entry in the public domain NCI Dictionary of Cancer Terms
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Specimen from a parotid gland tumour. It was removed by
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Cawson's essentials of oral pathology and oral medicine
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Creative Commons Attribution 4.0 International License
3780: 1574: 48:. Unsourced material may be challenged and removed. 2988:Jaw joints, chewing muscles and bite abnormalities 766: 1851: 762: 760: 3907: 2188: 1018: 506:Salivary duct carcinoma, not otherwise specified 3343:Teeth, jaws, tongue and associated soft tissues 1352: 1173:Pathology and Genetics of Head and Neck Tumours 821: 1955:Hereditary benign intraepithelial dyskeratosis 856:(Ninth ed.). : Elsevier Health Sciences. 757: 600:to the salivary gland from a distant location) 3570: 2913:Neuralgia-inducing cavitational osteonecrosis 1560: 1353:Mino M, Pilch BZ, Faquin WC (December 2003). 1132: 1130: 1346: 1189: 609:Intraosseous (central) salivary gland tumors 320:Due to the diverse nature of salivary gland 1266: 1230: 1111: 1107: 1105: 1012: 316:Relative incidence of submandibular tumors. 189:. The major salivary glands consist of the 3577: 3563: 1567: 1553: 1157: 1127: 234:and induration (hardening) of the mucosa. 131: 1490: 1480: 1370: 1321: 1213: 169:, also known as mucous gland adenomas or 108:Learn how and when to remove this message 1163: 1136: 1102: 655: 587:Extranodal marginal zone B cell lymphoma 330: 311: 303: 241: 181:. The salivary glands are classified as 3540:Oral manifestations of systemic disease 2689:Acute necrotizing ulcerative gingivitis 1462: 1140:Surgical Pathology of the Head and Neck 999: 815: 509:Adenocarcinoma, not otherwise specified 487:Low-grade cribriform cystadenocarcinoma 3908: 2726:As a manifestation of systemic disease 3663:Polymorphous low-grade adenocarcinoma 3558: 3513: 3412: 3336: 3094: 2973: 2759: 2549: 2187: 1850: 1790: 1678: 1586: 1548: 966: 851: 677:Treatment may include the following: 451:Polymorphous low-grade adenocarcinoma 308:Relative incidence of parotid tumors. 2572:Gums and tooth-supporting structures 1463:Venturi, Sebastiano (January 2021). 943: 941: 885: 883: 881: 847: 845: 672:Royal College of Surgeons of England 523:Mammary analogue secretory carcinoma 280:Fine needle aspiration (FNA) biopsy: 46:adding citations to reliable sources 17: 3223:Papillary cystadenoma lymphomatosum 3095: 3066:Temporomandibular joint dysfunction 1537:. Atlanta: American Cancer Society. 13: 3658:Epithelial-myoepithelial carcinoma 2340:Maxillary lateral incisor agenesis 1824:Inflammatory papillary hyperplasia 456:Epithelial-myoepithelial carcinoma 14: 3937: 3768: 1372:10.1097/01.MP.0000096046.42833.C7 1240:Int. J. Radiat. Oncol. Biol. Phys 1202:Arch. Otolaryngol. Head Neck Surg 938: 878: 842: 533:Metastasizing pleomorphic adenoma 299: 3887: This article incorporates 3882: 3668:Hyalinizing clear cell carcinoma 3442:Cutaneous sinus of dental origin 3379:Obesity hypoventilation syndrome 3374:Central hypoventilation syndrome 3256:Carcinoma ex pleomorphic adenoma 2684:Necrotizing periodontal diseases 2664:Hereditary gingival fibromatosis 1576:Oral and maxillofacial pathology 1533:American Cancer Society (2017). 1505: 1112:Steve C Lee (22 December 2022). 518:Carcinoma ex pleomorphic adenoma 159:oral and maxillofacial pathology 22: 3288:Chronic sclerosing sialadenitis 2925:Osteoporotic bone marrow defect 2379:Keratocystic odontogenic tumour 1526: 1517: 1456: 1412: 1387: 1297: 1047: 721: 208: 33:needs additional citations for 3900:U.S. National Cancer Institute 3273:Sclerosing polycystic adenosis 3108:Benign lymphoepithelial lesion 993: 984: 773:Advances in Anatomic Pathology 666:from a 37-year-old man called 155:oral and maxillofacial surgery 1: 3467:Melkersson–Rosenthal syndrome 3416:Soft tissues around the mouth 3113:Ectopic salivary gland tissue 1137:Barnes L (23 December 2008). 750: 582:Diffuse large B-cell lymphoma 477:Sebaceous lymphadenocarcinoma 2637:Gingival cyst of the newborn 2246:Failure of eruption of teeth 1950:Hand, foot and mouth disease 1935:Focal epithelial hyperplasia 1873:Angina bullosa haemorrhagica 1819:Palatal cysts of the newborn 1742:Transient lingual papillitis 1283:10.1016/0924-4212(96)84897-3 1252:10.1016/0360-3016(93)90233-L 1124:Diagrams by Mikael Häggström 785:10.1097/PAP.0000000000000283 647: 237: 177:that form in the tissues of 7: 3629:malignant epithelial tumors 3165:Salivary gland diverticulum 3128:Necrotizing sialometaplasia 2139:Smokeless tobacco keratosis 2051:Basaloid squamous carcinoma 1033:10.1016/j.ejrad.2008.01.027 1000:Mounika, C (7 March 2016). 825:Cancer of the Head and Neck 733: 431:Malignant epithelial tumors 10: 3942: 3895:Dictionary of Cancer Terms 3175:Salivary gland hyperplasia 3123:HIV salivary gland disease 2632:Gingival cyst of the adult 2078:Oral florid papillomatosis 1791: 1679: 1215:10.1001/archotol.129.9.944 1114:"Salivary Gland Neoplasms" 892:"Salivary gland swellings" 822:Shah JP; Patel SG (2001). 548:Lymphoepithelial carcinoma 254:Physical exam and history: 3855: 3784: 3748: 3725: 3701: 3676: 3626: 3617: 3608: 3520: 3514: 3509: 3422: 3414:Orofacial soft tissues – 3408: 3349: 3332: 3180:Salivary gland hypoplasia 3103: 3090: 2994: 2969: 2908:Bisphosphonate-associated 2802:Idiopathic osteosclerosis 2777: 2755: 2578: 2545: 2273:Dentinogenesis imperfecta 2209: 2183: 1863: 1846: 1799: 1786: 1737:Median rhomboid glossitis 1687: 1674: 1595: 1582: 852:Odell, Edward W. (2017). 828:. PMPH-USA. p. 240. 467:Basal cell adenocarcinoma 463:, not otherwise specified 404:Inverted ductal papilloma 390:Nonsebaceous lymphadenoma 326:World Health Organization 144: 139: 130: 125: 3926:Salivary gland pathology 3921:Salivary gland neoplasia 3679:benign epithelial tumors 3648:Adenoid cystic carcinoma 3643:Mucoepidermoid carcinoma 3487:Orofacial granulomatosis 3266:Mucoepidermoid carcinoma 3251:Adenoid cystic carcinoma 3185:Salivary gland neoplasms 2976:Temporomandibular joints 2947:Periapical periodontitis 2679:Linear gingival erythema 2447:Regional odontodysplasia 2293:Enamel hypocalcification 1587: 1399:www.cancerresearchuk.org 745:Salivary gland pathology 596:(i.e. a tumor which has 446:Adenoid cystic carcinoma 441:Mucoepidermoid carcinoma 418:Sialadenoma papilliferum 341:Benign epithelial tumors 3653:Salivary duct carcinoma 3384:Obstructive sleep apnea 3150:Salivary duct stricture 2930:Paget's disease of bone 2427:Pulp canal obliteration 2268:Dentin hypersensitivity 2214:Amelogenesis imperfecta 2066:Squamous cell carcinoma 2046:Adenosquamous carcinoma 2033:Squamous cell papilloma 2010:Melanocytic oral lesion 1002:"Salivary Gland Tumors" 974:"Salivary Gland Cancer" 538:Squamous cell carcinoma 513:Myoepithelial carcinoma 502:Salivary duct carcinoma 492:Mucinous adenocarcinoma 57:"Salivary gland tumour" 3889:public domain material 3530:Hemifacial hypertrophy 3497:Pyostomatitis vegetans 3170:Salivary gland fistula 3160:Salivary gland atresia 3155:Salivary gland aplasia 3009:Mandibular dislocation 2980:muscles of mastication 2858:Calcifying odontogenic 2487:Vertical root fracture 2482:Cracked tooth syndrome 2457:Shovel-shaped incisors 2352:Wisdom tooth impaction 2234:Early childhood caries 2100:Benign mucous membrane 2061:Spindle cell carcinoma 1970:Intraoral dental sinus 1888:Burning mouth syndrome 1482:10.3390/ijerph18178934 674: 383:Sebaceous lymphadenoma 337: 317: 309: 247: 167:Salivary gland tumours 3775:Salivary gland cancer 3638:Acinic cell carcinoma 3339:Stomatognathic system 3241:Acinic cell carcinoma 2863:Glandular odontogenic 2015:Molluscum contagiosum 1275:Bull Cancer Radiother 1122:Updated: Jan 13, 2021 659: 572:Hematolymphoid tumors 436:Acinic cell carcinoma 411:Intraductal papilloma 334: 315: 307: 245: 126:Salivary gland tumour 3602:head and neck cancer 3482:Oral Crohn's disease 3437:Basal cell carcinoma 3076:Condylar hyperplasia 3061:Maxillary hypoplasia 2627:Gingival enlargement 2560:periodontal ligament 2166:Verruciform xanthoma 1898:Condyloma acuminatum 1277:. 83 Suppl: 125–9s. 740:Head and neck cancer 699:Fast neutron therapy 543:Large cell carcinoma 461:Clear cell carcinoma 140:Parotid gland tumour 42:improve this article 3688:Pleomorphic adenoma 3492:Perioral dermatitis 3228:Pleomorphic adenoma 3208:Monomorphic adenoma 3198:Canalicular adenoma 3071:Condylar hypoplasia 3004:Condylar resorption 2848:Lateral periodontal 2807:Mandibular fracture 2706:Periodontal abscess 2303:Turner's hypoplasia 2071:Verrucous carcinoma 2020:Morsicatio buccarum 2000:Lupus erythematosus 1913:Erythema multiforme 1829:Stomatitis nicotina 1427:(79 (8)): 1465–75. 497:Oncocytic carcinoma 472:Sebaceous carcinoma 372:Canalicular adenoma 347:Pleomorphic adenoma 3856:External resources 3535:Facial hemiatrophy 3389:Periodic breathing 3320:Sjögren's syndrome 3193:Basal cell adenoma 2957:Torus mandibularis 2935:Periapical abscess 2918:Osteoradionecrosis 2843:Buccal bifurcation 2822:Intraosseous cysts 2711:Periodontal trauma 2615:Pyogenic granuloma 2462:Supernumerary root 2415:Pulp calcification 2403:Premature eruption 2374:Odontogenic tumors 2171:White sponge nevus 2144:Submucous fibrosis 2088:Smoker's melanosis 1975:Irritation fibroma 1814:High-arched palate 1722:Foliate papillitis 1712:Cunnilingus tongue 1697:Black hairy tongue 1627:Congenital lip pit 675: 560:Soft tissue tumors 482:Cystadenocarcinoma 362:Basal cell adenoma 338: 318: 310: 248: 3879: 3878: 3765: 3764: 3761: 3760: 3721: 3720: 3552: 3551: 3548: 3547: 3505: 3504: 3404: 3403: 3328: 3327: 3233:Sebaceous adenoma 3086: 3085: 2965: 2964: 2876:Median mandibular 2871:Nasopalatine duct 2787:Alveolar osteitis 2751: 2750: 2738:Perio-endo lesion 2620:Congenital epulis 2541: 2540: 2298:Enamel hypoplasia 2179: 2178: 2154:Riga–Fede disease 2005:Melanocytic nevus 1945:Hairy leukoplakia 1908:Epulis fissuratum 1842: 1841: 1782: 1781: 1732:Geographic tongue 1670: 1669: 1182:978-92-832-2417-4 1164:Barnes L (2005). 1150:978-0-8493-9023-4 1072:10.1002/hed.25811 908:10.1136/bmj.e6794 835:978-1-55009-084-0 164: 163: 120:Medical condition 118: 117: 110: 92: 3933: 3903: 3886: 3885: 3782: 3781: 3706: 3681: 3631: 3624: 3623: 3615: 3614: 3579: 3572: 3565: 3556: 3555: 3511: 3510: 3410: 3409: 3334: 3333: 3203:Ductal papilloma 3092: 3091: 2971: 2970: 2868:Non-odontogenic: 2853:Globulomaxillary 2792:Buccal exostosis 2757: 2756: 2701:Peri-implantitis 2547: 2546: 2263:Dentin dysplasia 2185: 2184: 2161:Verruca vulgaris 2056:Mucosal melanoma 1903:Darier's disease 1878:Behçet's disease 1848: 1847: 1804:Bednar's aphthae 1788: 1787: 1676: 1675: 1662:Trumpeter's wart 1584: 1583: 1569: 1562: 1555: 1546: 1545: 1539: 1538: 1530: 1524: 1521: 1515: 1509: 1504: 1494: 1484: 1460: 1454: 1452: 1416: 1410: 1409: 1407: 1405: 1391: 1385: 1384: 1374: 1350: 1344: 1343: 1325: 1301: 1295: 1294: 1270: 1264: 1263: 1234: 1228: 1227: 1217: 1193: 1187: 1186: 1170: 1161: 1155: 1154: 1134: 1125: 1121: 1109: 1100: 1099: 1066:(9): 3211–3218. 1051: 1045: 1044: 1016: 1010: 1009: 997: 991: 988: 982: 981: 970: 964: 963: 961: 959: 945: 936: 935: 887: 876: 875: 849: 840: 839: 819: 813: 812: 764: 716:Targeted Therapy 620:Hybrid carcinoma 594:Secondary tumors 577:Hodgkin lymphoma 398:Ductal papilloma 135: 123: 122: 113: 106: 102: 99: 93: 91: 50: 26: 18: 3941: 3940: 3936: 3935: 3934: 3932: 3931: 3930: 3906: 3905: 3892: 3883: 3880: 3875: 3874: 3851: 3850: 3793: 3771: 3766: 3757: 3744: 3717: 3702: 3697: 3693:Warthin's tumor 3677: 3672: 3627: 3604: 3583: 3553: 3544: 3516: 3501: 3457:Ludwig's angina 3418: 3400: 3359:Mouth breathing 3345: 3324: 3145:Pneumoparotitis 3118:Frey's syndrome 3099: 3097:Salivary glands 3082: 2990: 2961: 2940:Phoenix abscess 2773: 2769:hard tissues – 2747: 2669:Hypercementosis 2588:Cementoblastoma 2574: 2537: 2251:Dens evaginatus 2205: 2175: 2127:Denture-related 2112:Plasmoacanthoma 2038:Keratoacanthoma 1859: 1857:Lining of mouth 1838: 1834:Torus palatinus 1795: 1778: 1759:Lingual thyroid 1717:Fissured tongue 1707:Crenated tongue 1683: 1666: 1652:Nasolabial cyst 1637:Herpes labialis 1591: 1578: 1573: 1543: 1542: 1531: 1527: 1522: 1518: 1461: 1457: 1417: 1413: 1403: 1401: 1393: 1392: 1388: 1365:(12): 1224–31. 1351: 1347: 1316:(11): 2007–10. 1302: 1298: 1271: 1267: 1235: 1231: 1194: 1190: 1183: 1168: 1162: 1158: 1151: 1135: 1128: 1123: 1110: 1103: 1060:Head & Neck 1052: 1048: 1017: 1013: 998: 994: 989: 985: 972: 971: 967: 957: 955: 953:medlineplus.gov 947: 946: 939: 888: 879: 864: 850: 843: 836: 820: 816: 765: 758: 753: 736: 724: 650: 352:Warthin's tumor 302: 268:MRI or CT Scan: 240: 211: 179:salivary glands 121: 114: 103: 97: 94: 51: 49: 39: 27: 12: 11: 5: 3939: 3929: 3928: 3923: 3918: 3877: 3876: 3873: 3872: 3860: 3859: 3857: 3853: 3852: 3849: 3848: 3837: 3818: 3794: 3789: 3788: 3786: 3785:Classification 3779: 3778: 3770: 3769:External links 3767: 3763: 3762: 3759: 3758: 3756: 3755: 3749: 3746: 3745: 3743: 3742: 3737: 3731: 3729: 3723: 3722: 3719: 3718: 3716: 3715: 3709: 3707: 3699: 3698: 3696: 3695: 3690: 3684: 3682: 3674: 3673: 3671: 3670: 3665: 3660: 3655: 3650: 3645: 3640: 3634: 3632: 3621: 3619:Salivary gland 3612: 3606: 3605: 3582: 3581: 3574: 3567: 3559: 3550: 3549: 3546: 3545: 3543: 3542: 3537: 3532: 3527: 3525:Eagle syndrome 3521: 3518: 3517: 3507: 3506: 3503: 3502: 3500: 3499: 3494: 3489: 3484: 3479: 3474: 3469: 3464: 3459: 3454: 3449: 3447:Cystic hygroma 3444: 3439: 3434: 3429: 3423: 3420: 3419: 3406: 3405: 3402: 3401: 3399: 3398: 3393: 3392: 3391: 3386: 3381: 3376: 3371: 3361: 3356: 3350: 3347: 3346: 3330: 3329: 3326: 3325: 3323: 3322: 3317: 3315:Sialolithiasis 3312: 3307: 3302: 3297: 3292: 3291: 3290: 3285: 3275: 3270: 3269: 3268: 3263: 3258: 3253: 3248: 3246:Adenocarcinoma 3243: 3235: 3230: 3225: 3220: 3215: 3213:Myoepithelioma 3210: 3205: 3200: 3195: 3182: 3177: 3172: 3167: 3162: 3157: 3152: 3147: 3142: 3141: 3140: 3130: 3125: 3120: 3115: 3110: 3104: 3101: 3100: 3088: 3087: 3084: 3083: 3081: 3080: 3079: 3078: 3073: 3063: 3058: 3057: 3056: 3051: 3046: 3041: 3036: 3031: 3026: 3021: 3011: 3006: 3001: 2995: 2992: 2991: 2967: 2966: 2963: 2962: 2960: 2959: 2954: 2949: 2944: 2943: 2942: 2932: 2927: 2922: 2921: 2920: 2915: 2910: 2900: 2895: 2890: 2889: 2888: 2886:Traumatic bone 2883: 2881:Median palatal 2878: 2873: 2865: 2860: 2855: 2850: 2845: 2840: 2835: 2819: 2814: 2809: 2804: 2799: 2794: 2789: 2784: 2778: 2775: 2774: 2753: 2752: 2749: 2748: 2746: 2745: 2740: 2735: 2734: 2733: 2728: 2723: 2713: 2708: 2703: 2698: 2693: 2692: 2691: 2681: 2676: 2674:Hypocementosis 2671: 2666: 2661: 2660: 2659: 2654: 2649: 2639: 2634: 2629: 2624: 2623: 2622: 2617: 2607: 2602: 2597: 2596: 2595: 2585: 2579: 2576: 2575: 2543: 2542: 2539: 2538: 2536: 2535: 2534: 2533: 2528: 2523: 2518: 2508: 2507: 2506: 2496: 2495: 2494: 2489: 2484: 2479: 2469: 2464: 2459: 2454: 2449: 2444: 2439: 2434: 2429: 2424: 2423: 2422: 2412: 2411: 2410: 2408:Neonatal teeth 2400: 2395: 2394: 2393: 2383: 2382: 2381: 2371: 2366: 2361: 2356: 2355: 2354: 2344: 2343: 2342: 2332: 2327: 2322: 2317: 2312: 2307: 2306: 2305: 2295: 2290: 2288:Ectopic enamel 2285: 2280: 2275: 2270: 2265: 2260: 2259: 2258: 2248: 2243: 2238: 2237: 2236: 2226: 2221: 2216: 2210: 2207: 2206: 2181: 2180: 2177: 2176: 2174: 2173: 2168: 2163: 2158: 2157: 2156: 2146: 2141: 2136: 2135: 2134: 2129: 2124: 2114: 2109: 2104: 2103: 2102: 2092: 2091: 2090: 2083:Oral melanosis 2080: 2075: 2074: 2073: 2068: 2063: 2058: 2053: 2048: 2040: 2035: 2022: 2017: 2012: 2007: 2002: 1997: 1992: 1987: 1982: 1977: 1972: 1967: 1962: 1957: 1952: 1947: 1942: 1937: 1932: 1931: 1930: 1920: 1915: 1910: 1905: 1900: 1895: 1890: 1885: 1883:Bohn's nodules 1880: 1875: 1870: 1868:Amalgam tattoo 1864: 1861: 1860: 1844: 1843: 1840: 1839: 1837: 1836: 1831: 1826: 1821: 1816: 1811: 1806: 1800: 1797: 1796: 1784: 1783: 1780: 1779: 1777: 1776: 1771: 1766: 1761: 1756: 1751: 1746: 1745: 1744: 1739: 1734: 1724: 1719: 1714: 1709: 1704: 1699: 1694: 1688: 1685: 1684: 1672: 1671: 1668: 1667: 1665: 1664: 1659: 1654: 1649: 1644: 1639: 1634: 1629: 1624: 1619: 1618: 1617: 1612: 1607: 1596: 1593: 1592: 1580: 1579: 1572: 1571: 1564: 1557: 1549: 1541: 1540: 1525: 1516: 1455: 1411: 1386: 1345: 1296: 1265: 1229: 1188: 1181: 1156: 1149: 1126: 1101: 1046: 1011: 992: 983: 965: 937: 877: 863:978-0702049828 862: 841: 834: 814: 779:(6): 371–379. 755: 754: 752: 749: 748: 747: 742: 735: 732: 723: 720: 713: 712: 696: 695: 687: 649: 646: 645: 644: 643: 642: 637: 627: 626: 625: 622: 611: 602: 601: 591: 590: 589: 584: 579: 569: 568: 567: 557: 556: 555: 550: 545: 540: 535: 530: 528:Carcinosarcoma 525: 520: 515: 510: 507: 504: 499: 494: 489: 484: 479: 474: 469: 464: 458: 453: 448: 443: 438: 428: 423: 422: 421: 414: 407: 395: 394: 393: 386: 374: 369: 364: 359: 357:Myoepithelioma 354: 349: 301: 300:Classification 298: 239: 236: 210: 207: 162: 161: 148: 142: 141: 137: 136: 128: 127: 119: 116: 115: 30: 28: 21: 9: 6: 4: 3: 2: 3938: 3927: 3924: 3922: 3919: 3917: 3914: 3913: 3911: 3904: 3901: 3897: 3896: 3890: 3871: 3867: 3866: 3862: 3861: 3858: 3854: 3847: 3843: 3842: 3838: 3836: 3832: 3828: 3827: 3823: 3819: 3817: 3813: 3809: 3805: 3804: 3800: 3796: 3795: 3792: 3787: 3783: 3776: 3773: 3772: 3754: 3751: 3750: 3747: 3741: 3738: 3736: 3733: 3732: 3730: 3728: 3724: 3714: 3711: 3710: 3708: 3705: 3700: 3694: 3691: 3689: 3686: 3685: 3683: 3680: 3675: 3669: 3666: 3664: 3661: 3659: 3656: 3654: 3651: 3649: 3646: 3644: 3641: 3639: 3636: 3635: 3633: 3630: 3625: 3622: 3620: 3616: 3613: 3611: 3607: 3603: 3599: 3595: 3591: 3587: 3580: 3575: 3573: 3568: 3566: 3561: 3560: 3557: 3541: 3538: 3536: 3533: 3531: 3528: 3526: 3523: 3522: 3519: 3512: 3508: 3498: 3495: 3493: 3490: 3488: 3485: 3483: 3480: 3478: 3475: 3473: 3470: 3468: 3465: 3463: 3460: 3458: 3455: 3453: 3450: 3448: 3445: 3443: 3440: 3438: 3435: 3433: 3430: 3428: 3427:Actinomycosis 3425: 3424: 3421: 3417: 3411: 3407: 3397: 3394: 3390: 3387: 3385: 3382: 3380: 3377: 3375: 3372: 3370: 3367: 3366: 3365: 3362: 3360: 3357: 3355: 3352: 3351: 3348: 3344: 3340: 3335: 3331: 3321: 3318: 3316: 3313: 3311: 3308: 3306: 3305:Sialodochitis 3303: 3301: 3298: 3296: 3293: 3289: 3286: 3284: 3281: 3280: 3279: 3276: 3274: 3271: 3267: 3264: 3262: 3259: 3257: 3254: 3252: 3249: 3247: 3244: 3242: 3239: 3236: 3234: 3231: 3229: 3226: 3224: 3221: 3219: 3216: 3214: 3211: 3209: 3206: 3204: 3201: 3199: 3196: 3194: 3191: 3188: 3187: 3186: 3183: 3181: 3178: 3176: 3173: 3171: 3168: 3166: 3163: 3161: 3158: 3156: 3153: 3151: 3148: 3146: 3143: 3139: 3136: 3135: 3134: 3131: 3129: 3126: 3124: 3121: 3119: 3116: 3114: 3111: 3109: 3106: 3105: 3102: 3098: 3093: 3089: 3077: 3074: 3072: 3069: 3068: 3067: 3064: 3062: 3059: 3055: 3052: 3050: 3047: 3045: 3042: 3040: 3037: 3035: 3032: 3030: 3027: 3025: 3022: 3020: 3017: 3016: 3015: 3012: 3010: 3007: 3005: 3002: 3000: 2997: 2996: 2993: 2989: 2985: 2984:malocclusions 2981: 2977: 2972: 2968: 2958: 2955: 2953: 2952:Stafne defect 2950: 2948: 2945: 2941: 2938: 2937: 2936: 2933: 2931: 2928: 2926: 2923: 2919: 2916: 2914: 2911: 2909: 2906: 2905: 2904: 2903:Osteonecrosis 2901: 2899: 2898:Osteomyelitis 2896: 2894: 2891: 2887: 2884: 2882: 2879: 2877: 2874: 2872: 2869: 2866: 2864: 2861: 2859: 2856: 2854: 2851: 2849: 2846: 2844: 2841: 2839: 2836: 2834: 2831: 2829: 2825: 2824: 2823: 2820: 2818: 2815: 2813: 2810: 2808: 2805: 2803: 2800: 2798: 2795: 2793: 2790: 2788: 2785: 2783: 2780: 2779: 2776: 2772: 2771:Bones of jaws 2768: 2764: 2758: 2754: 2744: 2741: 2739: 2736: 2732: 2729: 2727: 2724: 2722: 2719: 2718: 2717: 2716:Periodontitis 2714: 2712: 2709: 2707: 2704: 2702: 2699: 2697: 2696:Pericoronitis 2694: 2690: 2687: 2686: 2685: 2682: 2680: 2677: 2675: 2672: 2670: 2667: 2665: 2662: 2658: 2655: 2653: 2652:Granulomatous 2650: 2648: 2645: 2644: 2643: 2640: 2638: 2635: 2633: 2630: 2628: 2625: 2621: 2618: 2616: 2613: 2612: 2611: 2608: 2606: 2605:Eruption cyst 2603: 2601: 2598: 2594: 2591: 2590: 2589: 2586: 2584: 2581: 2580: 2577: 2573: 2569: 2565: 2561: 2557: 2553: 2548: 2544: 2532: 2529: 2527: 2524: 2522: 2519: 2517: 2514: 2513: 2512: 2509: 2505: 2502: 2501: 2500: 2497: 2493: 2490: 2488: 2485: 2483: 2480: 2478: 2475: 2474: 2473: 2470: 2468: 2465: 2463: 2460: 2458: 2455: 2453: 2450: 2448: 2445: 2443: 2440: 2438: 2435: 2433: 2432:Pulp necrosis 2430: 2428: 2425: 2421: 2418: 2417: 2416: 2413: 2409: 2406: 2405: 2404: 2401: 2399: 2396: 2392: 2391:Dens in dente 2389: 2388: 2387: 2384: 2380: 2377: 2376: 2375: 2372: 2370: 2367: 2365: 2362: 2360: 2357: 2353: 2350: 2349: 2348: 2345: 2341: 2338: 2337: 2336: 2333: 2331: 2328: 2326: 2323: 2321: 2318: 2316: 2313: 2311: 2308: 2304: 2301: 2300: 2299: 2296: 2294: 2291: 2289: 2286: 2284: 2283:Discoloration 2281: 2279: 2276: 2274: 2271: 2269: 2266: 2264: 2261: 2257: 2254: 2253: 2252: 2249: 2247: 2244: 2242: 2239: 2235: 2232: 2231: 2230: 2227: 2225: 2222: 2220: 2217: 2215: 2212: 2211: 2208: 2203: 2199: 2195: 2191: 2186: 2182: 2172: 2169: 2167: 2164: 2162: 2159: 2155: 2152: 2151: 2150: 2147: 2145: 2142: 2140: 2137: 2133: 2130: 2128: 2125: 2123: 2120: 2119: 2118: 2115: 2113: 2110: 2108: 2105: 2101: 2098: 2097: 2096: 2093: 2089: 2086: 2085: 2084: 2081: 2079: 2076: 2072: 2069: 2067: 2064: 2062: 2059: 2057: 2054: 2052: 2049: 2047: 2044: 2041: 2039: 2036: 2034: 2031: 2028: 2027: 2026: 2023: 2021: 2018: 2016: 2013: 2011: 2008: 2006: 2003: 2001: 1998: 1996: 1993: 1991: 1990:Lichen planus 1988: 1986: 1983: 1981: 1978: 1976: 1973: 1971: 1968: 1966: 1965:Herpes zoster 1963: 1961: 1958: 1956: 1953: 1951: 1948: 1946: 1943: 1941: 1940:Fordyce spots 1938: 1936: 1933: 1929: 1926: 1925: 1924: 1921: 1919: 1918:Erythroplakia 1916: 1914: 1911: 1909: 1906: 1904: 1901: 1899: 1896: 1894: 1891: 1889: 1886: 1884: 1881: 1879: 1876: 1874: 1871: 1869: 1866: 1865: 1862: 1858: 1854: 1849: 1845: 1835: 1832: 1830: 1827: 1825: 1822: 1820: 1817: 1815: 1812: 1810: 1807: 1805: 1802: 1801: 1798: 1794: 1789: 1785: 1775: 1772: 1770: 1767: 1765: 1762: 1760: 1757: 1755: 1752: 1750: 1747: 1743: 1740: 1738: 1735: 1733: 1730: 1729: 1728: 1725: 1723: 1720: 1718: 1715: 1713: 1710: 1708: 1705: 1703: 1702:Caviar tongue 1700: 1698: 1695: 1693: 1692:Ankyloglossia 1690: 1689: 1686: 1682: 1677: 1673: 1663: 1660: 1658: 1657:Sun poisoning 1655: 1653: 1650: 1648: 1645: 1643: 1640: 1638: 1635: 1633: 1630: 1628: 1625: 1623: 1620: 1616: 1613: 1611: 1608: 1606: 1603: 1602: 1601: 1598: 1597: 1594: 1590: 1585: 1581: 1577: 1570: 1565: 1563: 1558: 1556: 1551: 1550: 1547: 1536: 1529: 1520: 1513: 1508: 1502: 1498: 1493: 1488: 1483: 1478: 1474: 1470: 1466: 1459: 1450: 1446: 1442: 1438: 1434: 1430: 1426: 1422: 1415: 1400: 1396: 1390: 1382: 1378: 1373: 1368: 1364: 1360: 1356: 1349: 1341: 1337: 1333: 1329: 1324: 1319: 1315: 1311: 1307: 1300: 1292: 1288: 1284: 1280: 1276: 1269: 1261: 1257: 1253: 1249: 1246:(2): 235–40. 1245: 1241: 1233: 1225: 1221: 1216: 1211: 1207: 1203: 1199: 1192: 1184: 1178: 1174: 1167: 1160: 1152: 1146: 1142: 1141: 1133: 1131: 1119: 1115: 1108: 1106: 1097: 1093: 1089: 1085: 1081: 1077: 1073: 1069: 1065: 1061: 1057: 1050: 1042: 1038: 1034: 1030: 1027:(3): 419–36. 1026: 1022: 1015: 1007: 1003: 996: 987: 979: 975: 969: 954: 950: 944: 942: 933: 929: 925: 921: 917: 913: 909: 905: 901: 897: 893: 886: 884: 882: 873: 869: 865: 859: 855: 848: 846: 837: 831: 827: 826: 818: 810: 806: 802: 798: 794: 790: 786: 782: 778: 774: 770: 763: 761: 756: 746: 743: 741: 738: 737: 731: 728: 719: 717: 709: 708: 704: 703: 702: 700: 693: 692: 688: 685: 684: 680: 679: 678: 673: 669: 665: 664: 658: 654: 641: 638: 636: 635:Keratocystoma 633: 632: 631: 628: 623: 621: 618: 617: 615: 614:Hybrid tumors 612: 610: 607: 606: 605: 599: 595: 592: 588: 585: 583: 580: 578: 575: 574: 573: 570: 566: 563: 562: 561: 558: 554: 553:Sialoblastoma 551: 549: 546: 544: 541: 539: 536: 534: 531: 529: 526: 524: 521: 519: 516: 514: 511: 508: 505: 503: 500: 498: 495: 493: 490: 488: 485: 483: 480: 478: 475: 473: 470: 468: 465: 462: 459: 457: 454: 452: 449: 447: 444: 442: 439: 437: 434: 433: 432: 429: 427: 424: 420: 419: 415: 413: 412: 408: 406: 405: 401: 400: 399: 396: 392: 391: 387: 385: 384: 380: 379: 378: 375: 373: 370: 368: 365: 363: 360: 358: 355: 353: 350: 348: 345: 344: 343: 342: 333: 329: 327: 323: 314: 306: 297: 294: 290: 288: 284: 281: 277: 275: 271: 269: 265: 262: 258: 255: 251: 244: 235: 233: 229: 225: 222:damage (e.g. 221: 217: 206: 204: 200: 196: 195:submandibular 192: 188: 184: 180: 176: 172: 168: 160: 156: 152: 149: 147: 143: 138: 134: 129: 124: 112: 109: 101: 90: 87: 83: 80: 76: 73: 69: 66: 62: 59: –  58: 54: 53:Find sources: 47: 43: 37: 36: 31:This article 29: 25: 20: 19: 16: 3916:Rare cancers 3894: 3881: 3863: 3839: 3820: 3797: 3703: 3678: 3628: 3415: 3342: 3278:Sialadenitis 3237: 3189: 3054:Scissor bite 3049:Retrognathia 3034:Overeruption 3014:Malocclusion 2987: 2867: 2826: 2817:Micrognathia 2770: 2761:Periapical, 2647:Desquamative 2571: 2552:Periodontium 2526:Acid erosion 2467:Taurodontism 2398:Open contact 2310:Enamel pearl 2278:Dilaceration 2241:Concrescence 2042: 2029: 1856: 1809:Cleft palate 1769:Microglossia 1764:Macroglossia 1749:Glossoptosis 1647:Microcheilia 1642:Macrocheilia 1534: 1528: 1519: 1475:(17): 8934. 1472: 1468: 1458: 1424: 1420: 1414: 1402:. 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Specialty
Oncology
oral and maxillofacial surgery
oral and maxillofacial pathology
neoplasms
tumours
salivary glands
parotid
submandibular
sublingual
oral
xerostomia
facial nerve
facial palsy
paraesthesia
ulceration

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