464:
266:
29:
216:
193:
170:
491:
after a volunteer in Oxford developed illness following vaccination, but were soon resumed after consent by the
British regulators. In December 2020, the Serum Institute of India sought emergency approval for the vaccine developed with AstraZeneca, which was approved a month later. In March 2021, an
577:
The R21/Matrix-MTM malaria vaccine was jointly developed by the Jenner
Institute at Oxford University and Serum Institute of India, with support from various organizations including the European and Developing Countries Clinical Trials Partnership (EDCTP), the Wellcome Trust, and the European
574:'s adjuvant technology, demonstrated notable efficacy along with a positive safety profile. Furthermore, the Serum Institute of India had successfully established production capacity for 100 million doses annually, with plans to double this capacity over the next two years.
433:
As of 2023, the company is the world's largest vaccine producer by number of doses produced, manufacturing around 1.9 billion doses of vaccines each year with plans to produce 4 billion doses of vaccines. The products developed include tuberculosis vaccine
487:) doses of the vaccine for India and other low and middle-income countries. This target was later increased to 1 billion doses by the end of 2021. It was estimated to be priced at ₹225 (around $ 3) per dose. In September 2020, trials were halted by
1140:
1422:
1480:
814:"Poonawalla Investments AND Industries Private Limited Information - Poonawalla Investments AND Industries Private Limited Company Profile, Poonawalla Investments AND Industries Private Limited News on The Economic Times"
343:, India. The company set out to produce immunobiologicals, which were then being imported into India at high prices. Among the first products the Serum Institute of India manufactured in large quantities were the
1165:
996:
Kulkarni, Prasad S.; Sahai, Ashish; Gunale, Bhagwat; Dhere, Rajeev M (3 March 2017). "Development of a new purified vero cell rabies vaccine (Rabivax-S) at the serum institute of India Pvt Ltd".
1462:
418:
vaccine. In 2012, the company's first international acquisition was
Bilthoven Biologicals, a biopharmaceutical company in Netherlands. In 2016, with support from US-based Mass Biologics of
868:
1430:
1316:
1505:
1202:
1444:
1184:
524:
1334:
788:
1404:
1481:"Codagenix and Serum Institute of India Announce Commencement of First-in-Human Trial of COVI-VAC, A Single Dose, Intranasal Live Attenuated Vaccine for COVID-19"
1591:
1673:
970:
1245:
1264:
395:
products. As of 2014, the vaccines manufactured by the Serum
Institute of India have been used in international vaccination programmes run by the
1565:
622:
467:
A vial of the Oxford-AstraZeneca COVID-19 vaccine that is locally produced in the Serum
Institute of India (SII) as "Covishield" COVID-19 vaccine
1663:
1668:
733:
945:
1203:"Coronavirus (Covid-19) vaccine latest update: Oxford-AstraZeneca corona vaccine production starts; US says 2 billion doses 'ready to go'"
1678:
762:
1693:
419:
1653:
650:
1592:"Oxford R21/Matrix-M™ malaria vaccine receives WHO recommendation for use paving the way for global roll-out | University of Oxford"
276:
813:
527:
after receiving approval from DCGI. On 13 July 2021, RDIF published a press release saying SII is starting the production of
1683:
1698:
1166:"Covid-19 vaccine: Serum Institute signs up for 100 million doses of vaccines for India, low and middle-income countries"
555:
185:
1688:
852:
488:
1039:
895:"A post-marketing surveillance study of a human live-virus pandemic influenza A (H1N1) vaccine (Nasovac ®) in India"
700:
512:
404:
503:(Covovax) vaccine for India and other low and middle-income countries. The company would also produce Codagenix's
1265:"Serum Institute halts coronavirus vaccine trials in India after notice from DCGI over volunteer's illness in UK"
578:
Investment Bank (EIB). As of now, the vaccine has obtained licenses for use in Ghana, Nigeria, and
Burkina Faso.
531:
doses in
September 2021, with the intention to produce over 300 million doses of the vaccine in India per year.
1538:
563:
1361:
1658:
1141:"AstraZeneca & Serum Institute of India sign licensing deal for 1 million doses of Oxford vaccine"
559:
463:
396:
471:
Serum
Institute of India partnered with the British-Swedish multinational pharmaceutical company
597:
39:
1617:
554:
On
October 8, 2023, the R21/Matrix-M malaria vaccine received a recommendation for use by the
592:
380:
155:
567:
504:
480:
1220:
1090:
1065:
8:
372:
88:
1566:"What is the new anti-malaria vaccine cleared by WHO all about? Will it work for India?"
265:
1021:
921:
894:
734:"How this millennial CEO steered the world's largest vaccine maker during the pandemic"
316:
57:
1539:"Chinese hackers target Indian vaccine makers SII, Bharat Biotech, says security firm"
1246:"Serum Institute of India to provide Covid-19 vaccines through COVAX at Rs 225 a dose"
1463:"India's Serum Institute starts manufacturing Codagenix's potential Covid-19 vaccine"
1013:
926:
848:
376:
344:
145:
1025:
1005:
916:
906:
408:
328:
1009:
675:
1506:"Serum Institute gets DCGI's nod to manufacture Covid vaccine Sputnik V in India"
1185:"Oxford COVID-19 vaccine at least 6 months away from launch: Serum Institute CEO"
1115:
845:
India's
Healthcare Industry: Innovation in Delivery, Financing, and Manufacturing
126:
821:
28:
587:
230:
483:. It was reported that Serum Institute of India would provide 100 million (10
1647:
1405:"Serum Institute, Novavax in covid vaccine deal, may produce 100 crore doses"
705:
312:
291:
278:
52:
1120:
Vaccination as per the National Immunization schedule by Government of India
1017:
930:
388:
150:
1289:
893:
Kulkarni, Prasad S.; Raut, Sidram K.; Dhere, Rajeev M. (27 October 2014).
763:"Coronavirus vaccine: Why does India's Serum Institute have a head start?"
1445:"Serum Institute starts manufacturing Codagenix's nasal COVID-19 vaccine"
1423:"Novavax signs COVID-19 vaccine supply deal with India's Serum Institute"
1386:
500:
472:
439:
359:. The company's product lines was expanded to include different types of
356:
352:
103:
1317:"Serum Institute to resume Covid-19 vaccine trial after DGCI gives nod"
1040:"Serum Institute to focus on supplying COVID-19 vaccine to India first"
543:
539:
240:
208:
1523:
911:
528:
520:
415:
364:
348:
971:"Fast-acting anti-rabies drug set for India launch - Times of India"
789:"Indian vaccine giant Serum plans African plant in global expansion"
507:
384:
324:
542:
targeted the Serum Institute of India's intellectual property for
1543:
701:"Serum Institute of India Pvt. Ltd.: Private Company Information"
571:
535:
496:
476:
450:, and other vaccinations for the childhood vaccination schedule.
392:
360:
256:
140:
1638:
1362:"India Approves Oxford-AstraZeneca Covid-19 Vaccine and 1 Other"
339:
The Serum Institute of India was founded in 1966 in the city of
423:
400:
1335:"India will have Covid-19 vaccine within days: AIIMS director"
426:
agent, Rabies Human Monoclonal Antibody (RMAb), also known as
484:
447:
368:
651:"Bilthoven Biologicals acquired by Serum Institute of India"
525:
Gamaleya Research Institute of Epidemiology and Microbiology
1618:"Serum Institute Of India. Press Release - 02 October 2023"
422:, the Serum Institute of India invented a fast-acting anti-
340:
320:
99:
1387:"Covid vaccine: India shortfall behind UK's supply delay"
538:
reported that Chinese state-backed cyber-espionage group
411:
and engages in research, development, and manufacturing.
995:
495:
Serum Institute of India also reached an agreement with
570:
and the Serum Institute of India in collaboration with
1290:"Oxford vaccine trial paused as participant falls ill"
492:
agreement was reached to supply some doses to the UK.
414:
In 2009, the company began developing an intranasal
407:(PAHO). The Serum Institute of India is run by the
16:
Indian biotechnology and biopharmaceuticals company
1221:"Indian company aims for a billion Covid vaccines"
892:
383:. Besides vaccine, the company also manufactures
331:in 1966 and is a part of Cyrus Poonawalla Group.
1645:
847:. Cambridge University Press. pp. 488–489.
869:"India developing indigenous swine flu vaccine"
549:
458:
566:(MPAG). The vaccine, jointly developed by The
1359:
946:"Serum Institute buys Bilthoven Biologicals"
943:
323:. It is the world's largest manufacturer of
1674:Biotechnology companies established in 1966
453:
623:"Serum Institute of India Private Limited"
420:University of Massachusetts Medical School
264:
1353:
920:
910:
617:
615:
613:
1182:
760:
462:
22:Serum Institute of India Private Limited
899:Human Vaccines & Immunotherapeutics
523:vaccine in India in collaboration with
1646:
761:Krishnan, Murali (29 September 2020).
727:
725:
723:
610:
1664:Manufacturing companies based in Pune
1360:Schmall E, Yasir S (3 January 2021).
1314:
842:
786:
479:(Covishield) in partnership with the
1669:Indian companies established in 1966
1315:Ghosh, Poulomi (12 September 2020).
756:
754:
731:
1536:
1183:Banerjee, Shoumojit (7 July 2020).
944:Unnikrishnan, C. H. (4 July 2012).
720:
556:Strategic Advisory Group of Experts
13:
1679:1966 establishments in Maharashtra
1262:
14:
1710:
1694:Pharmaceutical companies of India
1632:
751:
732:Choo, Olivia (16 December 2022).
1654:Biotechnology companies of India
1537:Das, Krishna N. (1 March 2021).
1066:"Serum Institute Tubervac (BCG)"
499:for the production of Novavax's
405:Pan American Health Organization
215:
214:
192:
191:
169:
168:
27:
1610:
1584:
1558:
1530:
1516:
1498:
1473:
1455:
1437:
1429:. 5 August 2020. Archived from
1415:
1397:
1379:
1327:
1308:
1282:
1256:
1238:
1213:
1195:
1176:
1158:
1133:
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1083:
1058:
1032:
989:
963:
937:
886:
861:
247:Vakzine Projekt Management GmbH
836:
806:
780:
693:
668:
643:
519:The company also manufactured
1:
1010:10.1080/14760584.2017.1294068
787:Kalra, Aditya (24 May 2022).
603:
564:Malaria Policy Advisory Group
327:by volume. It was founded by
311:) is an Indian multinational
225:(US$ 1.3 billion) (FY22)
202:(US$ 2.1 billion) (FY22)
179:(US$ 3.1 billion) (FY22)
550:R21/Matrix-M malaria vaccine
459:COVID-19 vaccine development
7:
1684:Biopharmaceutical companies
581:
510:vaccine CDX-005 (tradename
72:; 58 years ago
10:
1715:
1699:COVID-19 vaccine producers
1091:"Serum Institute Poliovac"
334:
998:Expert Review of Vaccines
843:Burns, Lawton R. (2014).
560:World Health Organization
397:World Health Organization
251:
239:
229:
206:
183:
164:
133:
120:
110:
95:
84:
66:
45:
35:
26:
1689:Immunology organizations
1095:Serum Institute of India
1070:Serum Institute of India
454:Notable vaccine projects
305:Serum Institute of India
245:Bilthoven Biologicals BV
655:www.thepharmaletter.com
292:18.505110°N 73.945453°E
1622:www.seruminstitute.com
1116:"Vaccination Schedule"
598:Biotechnology in India
468:
235:Cyrus Poonawalla Group
156:over-the-counter drugs
1170:The Financial Express
593:Biological E. Limited
466:
381:meningococcal vaccine
1469:. 22 September 2020.
1451:. 22 September 2020.
568:University of Oxford
505:nasally administered
481:University of Oxford
373:combination vaccines
297:18.505110; 73.945453
288: /
91:(Chairman & MD)
89:Cyrus S. Poonawalla
23:
1570:The Indian Express
1366:The New York Times
1341:. 31 December 2021
1296:. 9 September 2020
1250:The Indian Express
1207:The Indian Express
1145:The Economic Times
1046:. 23 November 2020
977:. 24 February 2016
975:The Times of India
873:The Times of India
818:The Economic Times
469:
319:company, based in
317:biopharmaceuticals
146:biopharmaceuticals
58:Biopharmaceuticals
21:
1659:Vaccine producers
1433:on 6 August 2020.
377:influenza vaccine
345:tetanus antitoxin
272:
271:
1706:
1639:Official website
1626:
1625:
1614:
1608:
1607:
1605:
1603:
1598:. 2 October 2023
1588:
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1579:
1577:
1572:. 3 October 2023
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1441:
1435:
1434:
1419:
1413:
1412:
1411:. 7 August 2020.
1401:
1395:
1394:
1393:. 18 March 2021.
1383:
1377:
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1252:. 7 August 2020.
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1172:. 7 August 2020.
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912:10.4161/hv.22317
890:
884:
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858:
840:
834:
833:
831:
829:
820:. Archived from
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409:Poonawalla Group
329:Cyrus Poonawalla
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24:
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1339:Hindustan Times
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1321:Hindustan Times
1313:
1309:
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1297:
1288:
1287:
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1271:
1263:Sharma, Milan.
1261:
1257:
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1229:
1227:
1219:
1218:
1214:
1209:. 10 June 2020.
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680:vpm-consult.com
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584:
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534:In March 2021,
475:for developing
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337:
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259:.seruminstitute
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127:Adar Poonawalla
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62:
17:
12:
11:
5:
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1696:
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1641:
1634:
1633:External links
1631:
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1583:
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1529:
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1512:. 4 June 2021.
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1004:(4): 303–311.
988:
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905:(1): 122–124.
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767:Deutsche Welle
750:
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588:Bharat Biotech
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854:9781316021217
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