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Sofia Simmonds

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275:, Fruton recounts that the "delay had adverse effect on Topsy's personal research, but the recognition of the merits of her scientific work and the quality of her contributions as a teacher could no longer be denied" by then. Fruton and Simmonds remained at Yale in the 1950s, when Fruton had the opportunity to join departments at other universities, in part because Simmonds—as a woman and the wife of a senior scientist—would have had even fewer opportunities for an independent career elsewhere. 270:
Fruton became a full professor in 1950, and subsequently became chairman of his department; Simmonds only became associate professor by 1959, and she was initially denied promotion to full professorship in 1966, only reaching that rank in 1975, nearly 30 years after starting at Yale. In his memoir
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In 1945, Fruton and Simmonds began working at Yale: Fruton as an associate professor and Simmonds as an instructor of physiological chemistry. The next year, Simmonds joined the Yale laboratory of
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Sofia, who went by the childhood nickname "Topsy" throughout her life, was the second child of Lionel Julius Simmonds and Clara Gottfried Simmonds. She was raised in
338: 251:, completing her PhD in biochemistry in 1942 and continuing as a research associate until she and Fruton moved to New Haven, Connecticut in 1945. 595: 585: 263:. Opportunities for career advancement for women scientists were very limited at the time, and discrimination (often in the form of anti- 228: 191:
there, Simmonds became a full professor of biochemistry in 1975, and later served as Associate Dean of Yale College. With her husband
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American Men & Women of Science: A Biographical Directory of Today's Leaders in Physical, Biological and Related Sciences. Index
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in 1933; the two began courting and they married in 1936. After high school and several months as a laboratory assistant at the
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rules) prevented the advancement of women scientists who worked in the same field as their husbands, as Simmonds did.
605: 470: 580: 220: 353: 590: 546: 520: 314: 283: 200: 235:, where she earned a BA in chemistry in 1938. After that, she started graduate work in the lab of 240: 462: 456: 54: 159: 97: 570: 565: 8: 244: 236: 188: 176: 143: 180: 77: 382: 542: 516: 466: 423: 310: 299:. New York: John Wiley & Sons Inc. 1953 (first edition), 1958 (second edition). 248: 138: 510: 417: 304: 232: 184: 131: 73: 559: 224: 192: 87: 279: 260: 204: 121: 117: 512:
Notable women in the physical sciences : a biographical dictionary
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Notable women in the physical sciences : a biographical dictionary
199:, the first comprehensive biochemistry textbook. Simmonds received the 166: 158:(July 31, 1917 – July 27, 2007) was an American biochemist who studied 278:
In 1969, after being nominated by Edward Tatum, Simmonds received the
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Womeon Scientists in America: Before Affirmative Action: 1940–1972
415: 171: 163: 541:. New Haven, Connecticut: Epikouros Press. pp. 66–119. 371:"In Memoriam: Biochemists Joseph Fruton and Sofia Simmonds" 363: 239:(who had been Fruton's advisor), but soon transferred to 515:(1. publ. ed.). Westport, Conn. : Greenwood Press. 309:(1. publ. ed.). Westport, Conn.: Greenwood Press. 247:. She worked in Vigneaud's laboratory on the study of 231:(where Fruton was earning his PhD), Simmonds attended 461:. Baltimore: Johns Hopkins University Press. p.  210: 346:Proceedings of the American Philosophical Society 219:, where her father was the superintendent of the 557: 509:Shearer, Benjamin F; Shearer, Barbara (1997). 508: 488: 486: 484: 482: 409: 416:Pamela M. Kalte; Katherine H. Nemeh (2003). 479: 229:Columbia College of Physicians and Surgeons 397: 187:. After decades as a researcher and then 454: 436: 302: 295:Fruton, Joseph S., and Sofia Simmonds. 596:20th-century American women scientists 558: 195:, Simmonds coauthored the influential 586:Weill Cornell Medical College alumni 13: 536: 502: 492: 442: 403: 352:(4). December 2009. Archived from 211:Youth, education, and early career 183:, she spent most of her career at 14: 627: 530: 381:(2). 2007-09-14. Archived from 616:Chemists from New York (state) 601:20th-century American chemists 455:Rossiter, Margaret W. (1995). 448: 331: 1: 324: 303:Shearer, Benjamin F. (1997). 375:Yale Bulletin & Calendar 7: 611:21st-century American women 10: 632: 576:American women biochemists 537:Fruton, Joseph S. (1994). 175:. Following training with 284:American Chemical Society 201:American Chemical Society 156:Sofia S. "Topsy" Simmonds 149: 137: 127: 113: 106: 93: 83: 69: 61: 43: 28: 21: 606:American women academics 289: 581:Yale University faculty 254: 241:Cornell Medical College 591:Barnard College alumni 55:New Haven, Connecticut 160:amino acid metabolism 297:General Biochemistry 221:Hebrew Orphan Asylum 197:General Biochemistry 245:Vincent du Vigneaud 237:Hans Thacher Clarke 189:associate professor 177:Vincent du Vigneaud 144:Vincent du Vigneaud 16:American biochemist 495:, pp. 118–119 339:"Joseph S. Fruton" 181:Cornell University 78:Cornell University 23:Sophia S. Simmonds 429:978-0-7876-6531-9 153: 152: 108:Scientific career 98:Garvan–Olin Medal 623: 552: 526: 496: 490: 477: 476: 452: 446: 440: 434: 433: 422:. Thomson/Gale. 413: 407: 406:, pp. 66–74 401: 395: 394: 392: 390: 385:on 24 March 2014 367: 361: 360: 358: 343: 335: 320: 249:transmethylation 139:Doctoral advisor 102: 50: 38: 36: 19: 18: 631: 630: 626: 625: 624: 622: 621: 620: 556: 555: 549: 533: 523: 505: 503:Further reading 500: 499: 491: 480: 473: 453: 449: 441: 437: 430: 414: 410: 402: 398: 388: 386: 369: 368: 364: 356: 341: 337: 336: 332: 327: 317: 292: 257: 233:Barnard College 213: 185:Yale University 132:Yale University 100: 74:Barnard College 70:Alma mater 57: 52: 48: 34: 32: 24: 17: 12: 11: 5: 629: 619: 618: 613: 608: 603: 598: 593: 588: 583: 578: 573: 568: 554: 553: 547: 532: 529: 528: 527: 521: 504: 501: 498: 497: 478: 471: 447: 435: 428: 408: 396: 362: 359:on 2015-04-30. 329: 328: 326: 323: 322: 321: 315: 300: 291: 288: 256: 253: 243:to work under 212: 209: 151: 150: 147: 146: 141: 135: 134: 129: 125: 124: 115: 111: 110: 104: 103: 95: 91: 90: 85: 81: 80: 71: 67: 66: 63: 59: 58: 53: 51:(aged 89) 45: 41: 40: 30: 26: 25: 22: 15: 9: 6: 4: 3: 2: 628: 617: 614: 612: 609: 607: 604: 602: 599: 597: 594: 592: 589: 587: 584: 582: 579: 577: 574: 572: 569: 567: 564: 563: 561: 550: 544: 540: 535: 534: 524: 518: 514: 513: 507: 506: 494: 489: 487: 485: 483: 474: 472:0-8018-4893-8 468: 464: 460: 459: 451: 444: 439: 431: 425: 421: 420: 412: 405: 400: 384: 380: 376: 372: 366: 355: 351: 347: 340: 334: 330: 318: 312: 308: 307: 301: 298: 294: 293: 287: 285: 281: 276: 274: 268: 266: 262: 252: 250: 246: 242: 238: 234: 230: 226: 225:Joseph Fruton 222: 218: 208: 206: 202: 198: 194: 193:Joseph Fruton 190: 186: 182: 178: 174: 173: 168: 165: 161: 157: 148: 145: 142: 140: 136: 133: 130: 126: 123: 119: 116: 112: 109: 105: 99: 96: 92: 89: 88:Joseph Fruton 86: 82: 79: 75: 72: 68: 64: 60: 56: 47:July 27, 2007 46: 42: 39:July 31, 1917 31: 27: 20: 539:Eighty Years 538: 531:Bibliography 511: 457: 450: 445:, p. 80 438: 418: 411: 399: 387:. Retrieved 383:the original 378: 374: 365: 354:the original 349: 345: 333: 305: 296: 280:Garvan Medal 277: 273:Eighty Years 272: 269: 261:Edward Tatum 258: 214: 205:Garvan Medal 196: 170: 155: 154: 128:Institutions 122:microbiology 118:Biochemistry 107: 49:(2007-07-27) 571:2007 deaths 566:1917 births 62:Nationality 560:Categories 548:0964046709 522:0313293031 325:References 316:0313293031 167:metabolism 35:1917-07-31 217:Manhattan 207:in 1969. 389:27 March 265:nepotism 65:American 282:of the 172:E. coli 164:peptide 545:  519:  493:Fruton 469:  443:Fruton 426:  404:Fruton 313:  114:Fields 101:(1969) 94:Awards 84:Spouse 357:(PDF) 342:(PDF) 290:Books 543:ISBN 517:ISBN 467:ISBN 424:ISBN 391:2014 311:ISBN 255:Yale 162:and 44:Died 29:Born 463:140 350:153 203:'s 179:at 169:in 562:: 481:^ 465:. 379:36 377:. 373:. 348:. 344:. 120:, 76:; 551:. 525:. 475:. 432:. 393:. 319:. 37:) 33:(

Index

New Haven, Connecticut
Barnard College
Cornell University
Joseph Fruton
Garvan–Olin Medal
Biochemistry
microbiology
Yale University
Doctoral advisor
Vincent du Vigneaud
amino acid metabolism
peptide
metabolism
E. coli
Vincent du Vigneaud
Cornell University
Yale University
associate professor
Joseph Fruton
American Chemical Society
Garvan Medal
Manhattan
Hebrew Orphan Asylum
Joseph Fruton
Columbia College of Physicians and Surgeons
Barnard College
Hans Thacher Clarke
Cornell Medical College
Vincent du Vigneaud
transmethylation

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