359:, but the prevailing modern view is that TMD is a cluster of related disorders with many common features. Indeed, some have suggested that, in the future, the term 'TMD' may be discarded as the different causes are fully identified and separated into different conditions. Sometimes, "temporomandibular joint dysfunction" is described as the most common form of temporomandibular disorder, whereas many other sources use the term 'temporomandibular disorder' synonymously, or instead of the term 'temporomandibular joint dysfunction'. In turn, the term 'temporomandibular disorder' is defined as "musculoskeletal disorders affecting the temporomandibular joints and their associated musculature. It is a collective term which represents a diverse group of pathologies involving the temporomandibular joint, the muscles of mastication, or both". Another definition of temporomandibular disorders is "a group of conditions with similar signs and symptoms that affect the temporomandibular joints, the muscles of mastication, or both." 'Temporomandibular disorder' is a term that creates confusion since it refers to a group of similarly symptomatic conditions, whilst many sources use the term temporomandibular disorders as a vague description, rather than a specific syndrome, and refer to any condition which may affect the temporomandibular joints (see table). The temporomandibular joint is susceptible to a huge range of diseases, some rarer than others, and there is no implication that all of these will cause any symptoms or limitation in function at all.
957:, which is both a lubricant to fill the joint spaces, and a means to convey nutrients to the tissues inside the joint. Behind the disc is loose vascular tissue termed the "bilaminar region" which serves as a posterior attachment for the disc and also fills with blood to fill the space created when the head of the condyle translates down the articular eminence. Due to its concave shape, sometimes the articular disc is described as having an anterior band, intermediate zone and a posterior band. When the mouth is opened, the initial movement of the mandibular condyle is rotational, and this involves mainly the lower joint space, and when the mouth is opened further, the movement of the condyle is translational, involving mainly the upper joint space. This translation movement is achieved by the condylar head sliding down the articular eminence, which constitutes the front border of the articular fossa. The function of the articular eminence is to limit the forwards movement of the condyle. The ligament directly associated with the TMJ is the
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the TMJs themselves are predominantly involved. This classification, which effectively divides TMD into 2 syndromes, is followed by the
American Academy of Orofacial Pain. However, since most people with TMD could be placed into both of these groups, which makes a single diagnosis difficult when this classification is used. The Research Diagnostic Criteria (RDC/TMD) allows for multiple diagnoses in an attempt to overcome the problems with other classifications. RDC/TMD considers temporomandibular disorders in 2 axes; axis I is the physical aspects, and axis II involves assessment of psychological status, mandibular function and TMD-related psychosocial disability. Axis I is further divided into 3 general groups. Group I are muscle disorders, group II are disc displacements and group III are joint disorders, although it is common for people with TMD to fit into more than one of these groups.
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derangement of the joint, which is instability or abnormal position of the articular disc. Clicking often accompanies either jaw opening or closing, and usually occurs towards the end of the movement. The noise indicates that the articular disc has suddenly moved to and from a temporarily displaced position (disk displacement with reduction) to allow completion of a phase of movement of the mandible. If the disc displaces and does not reduce (move back into position) this may be associated with locking. Clicking alone is not diagnostic of TMD since it is present in high proportion of the general population, mostly in people who have no pain. Crepitus often indicates arthritic changes in the joint, and may occur at any time during mandibular movement, especially lateral movements. Perforation of the disc may also cause crepitus. Due to the proximity of the TMJ to the
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lateral pterygoid from acting to stabilize the disc as it would do normally. As a biologic compensatory mechanism, the lower head tries to fill this role, hence the abnormal muscle activity during mouth closure. There is some evidence that anterior disc displacement is present in a proportion of TMD cases. Anterior disc displacement with reduction refers to abnormal forward movement of the disc during opening which reduces upon closing. Anterior disc displacement without reduction refers to an abnormal forward, bunched-up position of the articular disc which does not reduce. In this latter scenario, the disc is not intermediary between the condyle and the articular fossa as it should be, and hence the articular surfaces of the bones themselves are exposed to a greater degree of wear (which may predispose to osteoarthritis in later life).
581:) and arthrosis. The term arthrosis may cause confusion since in the specialized TMD literature it means something slightly different from in the wider medical literature. In medicine generally, arthrosis can be a nonspecific term for a joint, any disease of a joint (or specifically degenerative joint disease), and is also used as a synonym for osteoarthritis. In the specialized literature that has evolved around TMD research, arthrosis is differentiated from arthritis by the presence of low and no inflammation respectively. Both are however equally degenerative. The TMJs are sometimes described as one of the most used joints in the body. Over time, either with normal use or with parafunctional use of the joint, wear and degeneration can occur, termed osteoarthritis. Rheumatoid arthritis, an
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or the stabilization splint. Although occlusal splints are generally considered a reversible treatment, sometimes partial coverage splints lead to pathologic tooth migration (changes in the position of teeth). Normally splints are only worn during sleep, and therefore probably do nothing for people who engage in parafunctional activities during wakefulness rather than during sleep. There is slightly more evidence for the use of occlusal splints in sleep bruxism than in TMD. A splint can also have a diagnostic role if it demonstrates excessive occlusal wear after a period of wearing it each night. This may confirm the presence of sleep bruxism if it was in doubt. Soft splints are occasionally reported to worsen discomfort related to TMD. Specific types of occlusal splint are discussed below.
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from moving their jaw. After initial instruction, people are able to perform a physical therapy regimen at home. The most simple method is by regular stretching within pain tolerance, using the thumb and a finger in a "scissor" maneuver. Gentle force is applied until pain of resistance is felt, and then the position is held for several seconds. Commercial devices have been developed to carry out this stretching exercise (e.g. the "Therabite" appliance). Over time, the amount of mouth opening possible without pain can be gradually increased. A baseline record of the distance at the start of physical therapy (e.g. the number of fingers that can be placed vertically between the upper and lower incisors), can chart any improvement over time.
2064:. Some have criticized these occlusal reorganizations as having no evidence base, and irreversibly damaging the dentition on top of the damage already caused by bruxism. A "middle ground" view of these techniques is that occlusal adjustment in most cases of TMD is neither desirable nor helpful as a first-line treatment, and furthermore, with few exceptions, any adjustments should be reversible. However, most dentists consider this unnecessary overtreatment, with no evidence of benefit. Specifically, orthodontics and orthognathic surgery are not considered by most to be appropriate treatments for TMD. A systematic review investigating all the scientific studies carried out on occlusal adjustments in TMD concluded the following:
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between many of these chronic pain conditions has been hypothesized to be due to shared pathophysiological mechanisms, and they have been collectively termed "central sensitivity syndromes", although other apparent associations cannot be explained in this manner. Recently a plethora of research has substantiated a causal relationship between TMD and
Obstructive Sleep Apnea (OSA). Severe TMD restricts oral airway opening, and can result in a retrognathic posture that results in glossal blockage of the oropharynx as the tongue relaxes in sleep. This mechanism is exacerbated by alcohol consumption, as well as other chemicals that result in reduced myotonic status of the oropharynx.
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controversial. These techniques are sometimes termed "occlusal rehabilitation" or "occlusal equilibration". At its simplest, an occlusal adjustment involves selective grinding (with a dental drill) of the enamel of the occlusal surfaces of teeth, with the aim of allowing the upper teeth to fit with the lower teeth in a more harmonious way. However, there is much disagreement between proponents of these techniques on most of the aspects involved, including the indications and the exact goals. Occlusal adjustment can also be very complex, involving
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review investigating the possible relationship concluded that when self-reported bruxism is used to diagnose bruxism, there is a positive association with TMD pain, and when more strict diagnostic criteria for bruxism are used, the association with TMD symptoms is much lower. Self-reported bruxism is probably a poor method of identifying bruxism. There are also very many people who grind their teeth and who do not develop TMD. Bruxism and other parafunctional activities may play a role in perpetuating symptoms in some cases.
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occlusal factors in TMD are largely of historical interest. A causal relationship between occlusal factors and TMD was championed by
Ramfjord in the 1960s. A small minority of dentists continue to prescribe occlusal adjustments in the belief that this will prevent or treat TMD despite the existence of systematic reviews of the subject which state that there is no evidence for such practices, and the vast majority of opinion being that no irreversible treatment should be carried out in TMD (see
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1069:. The upper head also inserts at the fovea, but a part may be attached directly to the joint capsule and to the anterior and medial borders of the articular disc. The 2 parts of lateral pterygoid have different actions. The lower head contracts during mouth opening, and the upper head contracts during mouth closing. The function of the lower head is to steady the articular disc as it moves back with the condyle into the articular fossa. It is relaxed during mouth closure.
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factors which may precipitate it (trauma, occlusal changes, parafunction), and also factors which may prolong it (stress and again parafunction). Overall, two hypotheses have dominated research into the causes of TMD, namely a psychosocial model and a theory of occlusal dysharmony. Interest in occlusal factors as a causative factor in TMD was especially widespread in the past, and the theory has since fallen out of favor and become controversial due to lack of evidence.
1751:"On the basis of our analysis we conclude that the literature seems to suggest that there is insufficient evidence either for or against the use of stabilization splint therapy over other active interventions for the treatment of TMD. However, there is weak evidence to suggest that the use of stabilization splints for the treatment of TMD may be beneficial for reducing pain severity, at rest and on palpation, when compared to no treatment".
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2160:. There are no reported adverse events of acupuncture when used for TMD, and some suggest that acupuncture is best employed as an adjuvant to other treatments in TMD. However, some suggest that acupuncture may be no more effective than sham acupuncture, that many of the studies investigating acupuncture and TMD have significant risk of bias, and that the long term efficacy of acupuncture for TMD is unknown.
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49:
991:
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commonly used shortly after his initial work, but in modern times it has been dropped, partially because occlusal factors are now thought to play little, if any, role in the development of TMD, and also because ear problems are now thought to be less associated with TMD. Other historically important terms that were used for TMD include "TMJ disease" or "TMJ syndrome", which are now rarely used.
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syndrome', 'temporomandibular joint syndrome', 'temporomandibular dysfunction syndrome', 'temporomandibular dysfunction', 'temporomandibular disorder', 'temporomandibular syndrome', 'facial arthromyalgia', 'myofacial pain dysfunction syndrome', 'craniomandibular dysfunction' (CMD), 'myofacial pain dysfunction', 'masticatory myalgia', 'mandibular dysfunction', and 'Costen's syndrome'.
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1087:, joint noises are perceived to be much louder to the individual than to others. Often people with TMD are surprised that what sounds to them like very loud noises cannot be heard at all by others next to them. However, it is occasionally possible for loud joint noises to be easily heard by others in some cases and this can be a source of embarrassment e.g. when eating in company.
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609:. The interactions of these biological systems have been described as a vicious "anxiety-pain-tension" cycle which is thought to be frequently involved in TMD. Put simply, stress and anxiety cause grinding of teeth and sustained muscular contraction in the face. This produces pain which causes further anxiety which in turn causes prolonged muscular spasm at trigger points,
2171:(also termed manipulations or mobilizations) are sometimes used in the belief that this will treat TMD. Related conditions that are also claimed to be treatable by chiropractic include tension headaches and neck pain. Some sources suggest that there is some evidence of efficacy of chiropractic treatment in TMD, but the sources cited for these statements were
1747:. This kind of splint should be properly fitted to avoid exacerbating the problem and used for brief periods of time. The use of the splint should be discontinued if it is painful or increases existing pain. A systematic review of all the scientific studies investigating the efficacy of stabilization splints concluded the following:
2085:"There is no evidence to support or refute the use of orthodontic treatment for the treatment of TMD. In addition, there are no data which identify a link between active orthodontic intervention and the causation of TMD. Based on the lack of data, orthodontic treatment cannot be recommended for the treatment or prevention of TMD."
1768:"Hard stabilization appliances, when adjusted properly, have good evidence of modest efficacy in the treatment of TMD pain compared to non-occluding appliances and no treatment. Other types of appliances, including soft stabilization appliances, anterior positioning appliances, and anterior bite appliances, have some
2139:. Invasive surgical procedures in TMD may cause symptoms to worsen. Meniscectomy, also termed discectomy refers to surgical removal of the articular disc. This is rarely carried out in TMD, it may have some benefits for pain, but dysfunction may persist and overall it leads to degeneration or remodeling of the TMJ.
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The goals of a PT in reference to treatment of TMD should be to decrease pain, enable muscle relaxation, reduce muscular hyperactivity, and reestablish muscle function and joint mobility. PT treatment is non-invasive and includes self-care management in an environment to create patient responsibility
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The introduction of cone beam computed tomography (CBCT) imaging allowed a lower radiation dose to patients, in comparison to conventional CT. Hintze et al. compared CBCT and CT techniques and their ability to detect morphological TMJ changes. No significant difference was concluded in terms of their
780:). The variation of the COMT gene which produces less of this enzyme is associated with a high sensitivity to pain. Females with this variation, are at 2β3 times greater risk of developing TMD than females without this variant. However this theory is controversial since there is conflicting evidence.
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TMD is a symptom complex (i.e. a group of symptoms occurring together and characterizing a particular disease), which is thought to be caused by multiple, poorly understood factors, but the exact etiology is unknown. There are factors which appear to predispose to TMD (genetic, hormonal, anatomical),
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TMD mostly affects people in the 20 β 40 age group, and the average age is 33.9 years. People with TMD tend to be younger adults, who are otherwise healthy. Within the catchall umbrella of TMD, there are peaks for disc displacements at age 30, and for inflammatory-degenerative joint disorders at age
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A common scenario where a newly placed dental restoration (e.g. a crown or a filling) is incorrectly contoured, and creates a premature contact in the bite. This may localize all the force of the bite onto one tooth, and cause inflammation of the periodontal ligament and reversible increase in tooth
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and can be hard or soft. They can be designed to fit onto the upper teeth or the lower teeth. They may cover all the teeth in one arch (full coverage splint) or only some (partial coverage splint). Splints are also termed according to their intended mechanism, such as the anterior positioning splint
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Various diagnostic systems have been described. Some consider the
Research Diagnostic Criteria method the gold standard. Abbreviated to "RDC/TMD", this was first introduced in 1992 by Dworkin and LeResche in an attempt to classify temporomandibular disorders by etiology and apply universal standards
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TMD has been suggested to be associated with other conditions or factors, with varying degrees of evidence and some more commonly than others. 75% of people with TMD qualify for a fibromyalgia diagnosis and, conversely, 18% of people with fibromyalgia met diagnostic criteria for TMD. A possible link
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differences in the number of occlusal abnormalities in people with TMD and in people without TMD. There is also no evidence for a causal link between orthodontic treatment and TMD. The modern, mainstream view is that the vast majority of people with TMD, occlusal factors are not related. Theories of
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Occlusal factors as an etiologic factor in TMD is a controversial topic. Abnormalities of occlusion (problems with the bite) are often blamed for TMD but there is no evidence that these factors are involved. Occlusal abnormalities are incredibly common, and most people with occlusal abnormalities do
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in the muscles of mastication, or of the joint itself (preauricular pain β pain felt just in front of the ear). Pain is the defining feature of TMD and is usually aggravated by manipulation or function, such as when chewing, clenching, or yawning, and is often worse upon waking. The character of the
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solution ("Botox") is sometimes used to treat TMD. Injection of botox into the lateral pterygoid muscle has been investigated in multiple randomized control trials, and there is evidence that it is of benefit in TMD. It is theorized that spasm of lateral pterygoid causes anterior disc displacement.
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A stabilization splint is a hard acrylic splint that forces the teeth to meet in an "ideal" relationship for the muscles of mastication and the TMJs. It is claimed that this technique reduces abnormal muscular activity and promotes "neuromuscular balance". A stabilization splint is only intended to
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above. Between these articular surfaces is the articular disc (or meniscus), which is a biconcave, transversely oval disc composed of dense fibrous connective tissue. Each TMJ is covered by a fibrous capsule. There are tight fibers connecting the mandible to the disc, and loose fibers which connect
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mechanisms may be involved in sleep bruxism. If TMD pain and limitation of mandibular movement are greatest upon waking, and then slowly resolve throughout the day, this may indicate sleep bruxism. Conversely, awake bruxism tends to cause symptoms that slowly get worse throughout the day, and there
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Partial coverage splints are recommended by some experts, but they have the potential to cause unwanted tooth movements, which can occasionally be severe. The mechanism of this tooth movement is that the splint effectively holds some teeth out of contact and puts all the force of the bite onto the
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Studies have shown that tomography of the TMJ provided supplementary information that supersedes what is obtainable from clinical examination alone. However, the issues lies in the fact that it is impossible to determine whether certain patient groups would benefit more or less from a radiographic
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Noises from the TMJs are a symptom of dysfunction of these joints. The sounds commonly produced by TMD are usually described as a "click" or a "pop" when a single sound is heard and as "crepitation" or "crepitus" when there are multiple, grating, rough sounds. Most joint sounds are due to internal
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Trauma, both micro and macrotrauma, is sometimes identified as a possible cause of TMD; however, the evidence for this is not strong. Prolonged mouth opening (hyper-extension) is also suggested as a possible cause. It is thought that this leads to microtrauma and subsequent muscular hyperactivity.
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contracts during mouth closing (when it should relax), and is often tender to palpation. To theorize upon this observation, some have suggested that due to a tear in the back of the joint capsule, the articular disc may be displaced forwards (anterior disc displacement), stopping the upper head of
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TMD" (iTMD). Sometimes muscle-related (myogenous) TMD (also termed myogenous TMD, or TMD secondary to myofascial pain and dysfunction) is distinguished from joint-related TMD (also termed arthogenous TMD, or TMD secondary to true articular disease), based upon whether the muscles of mastication or
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According to the most recent analyses of epidemiologic data using the RDC/TMD diagnostic criteria, of all TMD cases, group I (muscle disorders) accounts for 45.3%, group II (disc displacements) 41.1%, and group III (joint disorders) 30.1% (individuals may have diagnoses from more than one group).
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of only 9 participants. One review concluded "inconclusive evidence in a favorable direction regarding mobilization and massage for TMD". Overall, although there is general agreement that chiropractic may be of comparable benefit to other manual therapies for lower back pain, there is no credible
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Orthodontic treatment, as described earlier, is sometimes listed as a possible predisposing factor in the development of TMD. On the other hand, orthodontic treatment is also often carried out in the belief that it may treat or prevent TMD. Another systematic review investigating the relationship
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to other methods of treatment in TMD. There are many different approaches described, but exercises aiming to increase the range of mandibular movements are commonly involved. Jaw exercises aim to directly oppose the negative effects of disuse that may occur in TMD, due to pain discouraging people
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US can be a useful alternative in initial investigation of internal TMJ dysfunctions especially in MRI contraindicated individuals despite its limitations. in addition to being less costly, US provides a quick and comfortable real-time imaging without exposing the individual to ionizing radiation
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Indications for MRI are pre-auricular pain, detection of joint clicking and crepitus, frequent incidents of subluxation and jaw dislocation, limited mouth opening with terminal stiffness, suspicion of neoplastic growth, and osteoarthritic symptoms. It is also useful for assessing the integrity of
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This is the adjustment or reorganizing of the existing occlusion, carried out in the belief that this will redistribute forces evenly across the dental arches or achieve a more favorable position of the condyles in the fossae, which is purported to lessen tooth wear, bruxism and TMD, but this is
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uses 'temporomandibular joint disorder'. A more complete list of synonyms for this topic is extensive, with some being more commonly used than others. In addition to those already mentioned, examples include 'temporomandibular joint pain dysfunction syndrome', 'temporomandibular pain dysfunction
668:
The relationship of bruxism with TMD is debated. Many suggest that sleep bruxism can be a causative or contributory factor to pain symptoms in TMD. Indeed, the symptoms of TMD overlap with those of bruxism. Others suggest that there is no strong association between TMD and bruxism. A systematic
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caused TMD, and placed emphasis on ear symptoms, such as tinnitus, otalgia, impaired hearing, and even dizziness. Specifically, Costen believed that the cause of TMD was mandibular over-closure, recommending a treatment revolving around building up the bite. The eponym "Costen syndrome" became
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139:
The prevalence of TMD in the global population is 34%. It varies by continent: the highest rate is in South
America at 47%, followed by Asia at 33%, Europe at 29%, and North America at 26%. About 20% to 30% of the adult population are affected to some degree. Usually people affected by TMD are
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for the development of TMD. In the 6 months before the onset, 50β70% of people with TMD report experiencing stressful life events (e.g. involving work, money, health or relationship loss). It has been postulated that such events induce anxiety and cause increased jaw muscle activity. Muscular
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and release of pain mediators. The pain discourages use of the masticatory system (a similar phenomenon in other chronic pain conditions is termed "fear avoidance" behavior), which leads to reduced muscle flexibility, tone, strength and endurance. This manifests as limited mouth opening and a
127:
TMDs have a range of causes and often co-occur with a number of overlapping medical conditions, including headaches, fibromyalgia, back pain, and irritable bowel. However, these factors are poorly understood, and there is disagreement as to their relative importance. There are many treatments
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For unknown reasons, females are more likely to be affected than males, in a ratio of about 2:1, although others report this ratio to be as high as 9:1. Females are more likely to request treatment for TMD, and their symptoms are less likely to resolve. Females with TMD are more likely to be
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Pain reported by the subject in response to palpation of 3 of the following muscle sites (right side and left side count as a separate sites for each muscle): posterior temporalis, middle temporalis, anterior temporalis, origin of masseter, insertion of masseter, posterior mandibular region,
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It is necessary that trials be performed isolating the type of exercise and manual techniques to allow a better understanding of the effectiveness of this treatment. Additionally, details of exercise, dosage, and frequency as well as details on manual techniques should be reported to create
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This method of imaging allows the visualisation of the joint's mineralised areas, therefore excluding the cartilage and soft tissues. A disadvantage of plain radiography is that images are prone to superimposition from surrounding anatomical structures, thereby complicating radiographic
2019:
Therapeutic exercise and Manual
Therapy (MT) are used to improve strength, coordination and mobility and to reduce pain. Treatment may focus on poor posture, cervical muscle spasms and treatment for referred cervical origin (pain referred from upper levels of the cervical spine) or
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Limitation of mandibular movement itself may lead to further problems involving the TMJs and the muscles of mastication. Changes in the synovial membrane may lead to a reduction in lubrication of the joint and contribute to degenerative joint changes. The muscles become weak, and
751:
TMD does not obviously run in families like a genetic disease. It has been suggested that a genetic predisposition for developing TMD (and chronic pain syndromes generally) could exist. This has been postulated to be explained by variations of the gene which codes for the enzyme
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mobility. The tooth may become tender to bite on. Here, the "occlusal adjustment" has already taken place inadvertently, and the adjustment aims to return to the pre-existing occlusion. This should be distinguished from attempts to deliberately reorganize the native occlusion.
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is the optimal choice for the imaging of soft tissues surrounding the TMJ. It allows three-dimensional evaluation of the axial, coronal and sagittal plane. It is the gold standard method for assessing disc position and is sensitive for intra-articular degenerative alterations.
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TMD". Despite multiple studies having been performed over the years, the cumulative evidence has been described as conflicting, with moderate evidence that TMD can occasionally follow whiplash injury. The research that suggests a link appears to demonstrate a low to moderate
2028:, break fibrous adhesions, stimulate synovial fluid production and reduce pain. Exercises and MT are safe and simple interventions that could potentially be beneficial for patients with TMD. No adverse events regarding exercise therapy and manual therapy have been reported.
1760:. Examples of partial coverage splints include the NTI-TSS ("nociceptive trigeminal inhibitor tension suppression system"), which covers the upper front teeth only. Due to the risks involved with long term use, some discourage the use of any type of partial coverage splint.
1644:, the treatment may often involve multiple approaches and be multidisciplinary. Most who are involved in treating and researching TMD now agree that any treatment carried out should not permanently alter the jaw or teeth, and should be reversible. To avoid permanent change,
1703:("fight or flight") response with cardiovascular and respiratory alterations. Relaxation techniques cause reduced sympathetic activity, including muscle relaxation and reducing sensitivity to external stimuli, and provoke a general sense of well-being and reduced anxiety.
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Limited range of mandibular movement, which may cause difficulty eating or even talking. There may be locking of the jaw, or stiffness in the jaw muscles and the joints, especially present upon waking. There may also be incoordination, asymmetry or deviation of mandibular
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About 75% of the general population may have at least one abnormal sign associated with the TMJ (e.g. clicking), and about 33% have at least one symptom of TMD. However, only in 3.6β7% will this be of sufficient severity to trigger the individual to seek medical advice.
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These conclusions were based largely on the fact that, despite many different scientific studies investigating this measure as a therapy, overall no statistically significant differences can be demonstrated between treatment with occlusal adjustment and treatment with
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is sometimes used for TMD. There is limited evidence that acupuncture is an effective symptomatic treatment for TMD. A short-term reduction in muscular pain of muscular origin can usually be observed after acupuncture in TMD, and this is more than is seen with
378:"Temporomandibular Pain and Dysfunction Syndrome β Aching in the muscles of mastication, sometimes with an occasional brief severe pain on chewing, often associated with restricted jaw movement and clicking or popping sounds." (Classification of Chronic Pain,
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2192:
of TMD is benign and self-limiting, with symptoms slowly improving and resolving over time. The prognosis is therefore good. However, the persistent pain symptoms, psychological discomfort, physical disability and functional limitations may detriment
1660:
Given the important role that psychosocial factors appear to play in TMD, psychosocial interventions could be viewed to be central to management of the condition. There is a suggestion that treatment of factors that modulate pain sensitivity such as
812:
are more likely to develop TMD, or may experience an exacerbation if they already had TMD. Several possible mechanisms by which estrogen might be involved in TMD symptoms have been proposed. Estrogen may play a role in modulating joint inflammation,
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La Touche R, Goddard G, De-la-Hoz JL, Wang K, Paris-Alemany A, Angulo-DΓaz-ParreΓ±o S, et al. (2010). "Acupuncture in the treatment of pain in temporomandibular disorders: a systematic review and meta-analysis of randomized controlled trials".
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has been suggested to be involved. The results of one study suggested that the periods of highest pain in TMD can be correlated with rapid periods of change in the circulating estrogen level. Low estrogen was also correlated to higher pain. In the
2197:. It has been suggested that TMD does not cause permanent damage and does not progress to arthritis in later life, however, degenerative disorders of the TMJ such as osteoarthritis are included within the spectrum of TMDs in some classifications.
1237:
Reciprocal clicking in TMJ (click on both vertical opening and closing that occurs at point 5 mm greater interincisal distance on opening than closing and is eliminated on protrusive opening), reproducible on 2 out of 3 consecutive trials;
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interpretation. It was concluded that there is no evidence to support the use of plain radiography in the diagnosis of joint erosions and osteophytes. It is reasonable to conclude that plain film can only be used to diagnose extensive lesions.
1428:
for research into TMD. This method involves 2 diagnostic axes, namely axis I, the physical diagnosis, and axis II, the psychologic diagnosis. Axis I contains 3 different groups which can occur in combinations of 2 or all 3 groups, (see table).
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434:
Sometimes distinction is made between acute TMD, where symptoms last for less than 3 months, and chronic TMD, where symptoms last for more than 3 months. Not much is known about acute TMD since these individuals do not typically attend in
124:(here also abbreviated to TMD) is taken to mean symptomatic (e.g. pain, limitation of movement, clicking) dysfunction of the temporomandibular joint. However, there is no single, globally accepted term or definition concerning this topic.
4694:
Wiese M, Wenzel A, Hintze H, Petersson A, Knutsson K, Bakke M, et al. (August 2008). "Osseous changes and condyle position in TMJ tomograms: impact of RDC/TMD clinical diagnoses on agreement between expected and actual findings".
1960:
release at the neuromuscular junction. The effects usually last for a period of months before they wear off. Complications include the creation of a "fixed" expression due to diffusion of the solution and subsequent involvement of the
1763:
An anterior positioning splint is a splint that designed to promote an anteriorly displaced disc. It is rarely used. A 2010 review of all the scientific studies carried out to investigate the use of occlusal splints in TMD concluded:
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where there is excessive clenching and grinding of the teeth. It can occur during sleep or whilst awake. The cause of bruxism itself is not completely understood, but psychosocial factors appear to be implicated in awake bruxism and
1562:. However, there is a high cost associated with this method of imaging, due to the need for sophisticated facilities. Caution should be taken in patient selection, as MRI is contraindicated in those with claustrophobic tendencies,
2031:
There have been positive results when using postural exercises and jaw exercises to treat both myogenous (muscular) and arthrogenous (articular) TMJ dysfunction. MT alone or in combination with exercises shows promising effects.
5184:
Bas B, YΔ±lmaz N, GΓΆkce E, Akan H (July 2011). "Ultrasound assessment of increased capsular width in temporomandibular joint internal derangements: relationship with joint pain and magnetic resonance grading of joint effusion".
1628:. This is due to the fact that US provides a dynamic and real-time location of the component of the joints, while providing adequate lubrication and washing, which can be confirmed by the joint space increase post-treatment.
5320:
Fricton J, Look JO, Wright E, Alencar FG, Chen H, Lang M, et al. (2010). "Systematic review and meta-analysis of randomized controlled trials evaluating intraoral orthopedic appliances for temporomandibular disorders".
366:, the term 'pain dysfunction syndrome' is in common use. In the United States, the term 'temporomandibular disorder' is generally favored. The American Academy of Orofacial Pain uses 'temporomandibular disorder', whilst the
2245:, and although he was not the first physician to describe TMD, he wrote extensively on the topic, starting in 1934, and was the first to approach the disorder in an integrated and systematic way. Costen hypothesized that
1518:
The distortion brought about by panoramic imaging decreases its overall reliability. Data concluded from a systematic review showed that only extensive erosions and large osteophytes can be detected by panoramic imaging.
1031:
They can be thought of in terms of the directions they move the mandible, with most being involved in more than one type of movement due to the variation in the orientation of muscle fibers within some of these muscles.
109:). The most important feature is pain, followed by restricted mandibular movement, and noises from the temporomandibular joints (TMJ) during jaw movement. Although TMD is not life-threatening, it can be detrimental to
3359:
1307:
One or more of the following self-reports of pain: pain in the region of the joint, pain in the joint during maximum unassisted opening, pain in the joint during assisted opening, and pain in the joint during lateral
4618:
Limchaichana N, Petersson A, Rohlin M (October 2006). "The efficacy of magnetic resonance imaging in the diagnosis of degenerative and inflammatory temporomandibular joint disorders: a systematic literature review".
4291:
1241:
Clicking in TMJ on both vertical range of motion (either opening or closing), reproducible on 2 out of 3 consecutive trials, and click during lateral excursion or protrusion, reproducible on 2 out of 3 consecutive
1109:
Pain originating from the muscles of mastication as a result of abnormal muscular function or hyperactivity. The muscular pain is frequently, but not always, associated with daytime clenching or nocturnal bruxism.
1095:
Pain symptoms in TMD can be thought of as originating from the joint (arthralgia), or from the muscles (myofascial), or both. There is a poor correlation between TMD pain severity and evidence of tissue pathology.
128:
available, although there is a general lack of evidence for any treatment in TMD, and no widely accepted treatment protocol. Common treatments include provision of occlusal splints, psychosocial interventions like
1784:
Medication is the main method of managing pain in TMD, mostly because there is little if any evidence of the effectiveness of surgical or dental interventions. Many drugs have been used to treat TMD pain, such as
6394:
6379:
6364:
1992:
in the muscles, and this is hypothesized to inactivate trigger points and disrupt small fibrous adhesions within the muscle that have formed following surgery or muscular shortening due to restricted movement.
585:
joint disease, can also affect the TMJs. Degenerative joint diseases may lead to defects in the shape of the tissues of the joint, limitation of function (e.g. restricted mandibular movements), and joint pain.
1122:
rarely occurs. If the greatest reduction in movement occurs upon waking then this may indicate that there is concomitant sleep bruxism. In other cases the limitation in movement gets worse throughout the day.
983:
The muscles of mastication are paired on each side and work together to produce the movements of the mandible. The main muscles involved are the masseter, temporalis and medial and lateral pterygoid muscles.
487:
pain is usually dull or aching, poorly localized, and intermittent, although it can sometimes be constant. The pain is more usually unilateral (located on one side) rather than bilateral. It is rarely severe.
2000:(TENS), which may override pain by stimulation of superficial nerve fibers and lead to pain reduction which extends after the time where the TENS is being actually being applied, possibly due to release of
1137:
Degenerative joint disease, such as osteoarthritis or organic degeneration of the articular surfaces, recurrent fibrous or bony ankylosis, developmental abnormality, or pathologic lesions within the TMJ.
1379:
to detect. Clicks of the joint may also be palpated, over the joint itself in the preauricular region, or via a finger inserted in the external acoustic meatus, which lies directly behind the TMJ. The
5144:
Jank S, Zangerl A, Kloss FR, Laimer K, Missmann M, Schroeder D, Mur E (January 2011). "High resolution ultrasound investigation of the temporomandibular joint in patients with chronic polyarthritis".
374:
The lack of standardization in terms is not restricted to medical papers. Notable internationally recognized sources vary in both their preferred term, and their offered definition. For example:
2180:
evidence of efficacy in other conditions, including TMD. However, there is some evidence of possible adverse effects from cervical (neck) vertebral manipulation, which sometimes may be serious.
1355:
1501:
When clinical examination alone is unable to bring sufficient detail to ascertain the state of the TMJ, imaging methods can act as an adjuvant to clinical examination in the diagnosis of TMD.
5782:
Jung A, Shin BC, Lee MS, Sim H, Ernst E (May 2011). "Acupuncture for treating temporomandibular joint disorders: a systematic review and meta-analysis of randomized, sham-controlled trials".
4659:
Hussain AM, Packota G, Major PW, Flores-Mir C (February 2008). "Role of different imaging modalities in assessment of temporomandibular joint erosions and osteophytes: a systematic review".
1681:
is suggested by some to be appropriate for TMD. Studies have suggested that it may even be more beneficial than occlusal splint therapy, and has comparable effects to relaxation techniques.
637:
Others argue that a link between muscular hyperactivity and TMD has not been convincingly demonstrated, and that emotional distress may be more of a consequence of pain rather than a cause.
421:
injury, although the evidence for this is not conclusive. This type of TMD is sometimes termed "posttraumatic TMD" (pTMD) to distinguish it from TMD of unknown cause, sometimes termed "
2008:, theorized to produce tissue heating, alter blood flow and metabolic activity at a level that is deeper than possible with surface heat applications. There is tentative evidence that
447:
Signs and symptoms of temporomandibular joint disorder vary in their presentation. The symptoms will usually involve more than one of the various components of the masticatory system,
3741:
Orlando B, Manfredini D, Salvetti G, Bosco M (2007). "Evaluation of the effectiveness of biobehavioral therapy in the treatment of temporomandibular disorders: a literature review".
2241:
Temporomandibular disorders were described as early as ancient Egypt. An older name for the condition is "Costen's syndrome", eponymously referring to James B. Costen. Costen was an
1173:. Despite some of these findings, some researchers question whether TMJD therapy can reduce symptoms in the ear, and there is currently an ongoing debate to settle the controversy.
2858:
Aggarwal VR, Lovell K, Peters S, Javidi H, Joughin A, Goldthorpe J (November 2011). Aggarwal VR (ed.). "Psychosocial interventions for the management of chronic orofacial pain".
5463:
Al-Moraissi, EA, et al. (January 2024). "Treatments for painful temporomandibular disc displacement with reduction: a network meta-analysis of randomized clinical trials".
1941:, into the muscles (e.g. the temoralis muscle or its tendon) are also sometimes used. Local anesthetics may provide temporary pain relief, and steroids inhibit pro-inflammatory
4972:"Diagnostic performance of magnetic resonance imaging for detecting osseous abnormalities of the temporomandibular joint and its correlation with cone beam computed tomography"
2068:"There is an absence of evidence of effectiveness for occlusal adjustment. Based on these data occlusal adjustment cannot be recommended for the treatment or prevention of TMD.
716:
injuries (sudden neck hyper-extension usually occurring in road traffic accidents), and the development of TMD. This has been termed "post-traumatic TMD", to separate it from "
1772:
evidence of efficacy in reducing TMD pain. However, the potential for adverse events with these appliances is higher and suggests the need for close monitoring in their use."
1756:
teeth which the splint covers. This can cause the covered teeth to be intruded, and those that are not covered to over-erupted. I.e. a partial coverage splint can act as a
1045:
Lateral movements β Medial and lateral pterygoid (the ipsilateral temporalis and the pterygoid muscles of the contralateral side pull the mandible to the ipsilateral side).
949:
the disc to the temporal bone, meaning there are in effect 2 joint capsules, creating an upper joint space and a lower joint space, with the articular disc in between. The
501:
Other signs and symptoms have also been described, although these are less common and less significant than the cardinal signs and symptoms listed above. Examples include:
3363:
1984:
It has been suggested that massage therapy for TMD improves both the subjective and objective health status. "Friction massage" uses surface pressure to cause temporary
7585:
701:, during singing or wind instrument practice (really these can be thought of as parafunctional activities). Damage may be incurred during violent yawning, laughing,
1484:
The advantages brought about by diagnostic imaging mainly lie within diagnosing TMD of articular origin. Additional benefits of imaging the TMJ are as follows:
621:
Persons with TMD have a higher prevalence of psychological disorders than people without TMD. People with TMD have been shown to have higher levels of anxiety,
3388:
1448:
The
International Headache Society's diagnostic criteria for "headache or facial pain attributed to temporomandibular joint disorder" is similar to the above:
367:
936:
The temporomandibular joints are the dual articulation of the mandible with the skull. Each TMJ is classed as a "ginglymoarthrodial" joint since it is both a
7659:
7644:
7348:
7336:
3892:
Manfredini D, Lobbezoo F (June 2010). "Relationship between bruxism and temporomandibular disorders: a systematic review of literature from 1998 to 2008".
3201:
Al-Ani MZ, Davies SJ, Gray RJ, Sloan P, Glenny AM (2004). Al-Ani MZ (ed.). "Stabilisation splint therapy for temporomandibular pain dysfunction syndrome".
4486:
2306:
Mujakperuo HR, Watson M, Morrison R, Macfarlane TV (October 2010). "Pharmacological interventions for pain in patients with temporomandibular disorders".
1150:
Sometimes TMD pain can radiate or be referred from its cause (i.e. the TMJ or the muscles of mastication) and be felt as headaches, earache or toothache.
3360:"Classification of Chronic Pain, Part II, B. Relatively Localized Syndromes of the Head and Neck; Group III: Craniofacial pain of musculoskeletal origin"
7841:
5102:
Landes CA, Goral WA, Sader R, Mack MG (May 2006). "3-D sonography for diagnosis of disk dislocation of the temporomandibular joint compared with MRI".
4932:
Hintze H, Wiese M, Wenzel A (May 2007). "Cone beam CT and conventional tomography for the detection of morphological temporomandibular joint changes".
494:
Noises from the joint during mandibular movement, which may be intermittent. Joint noises may be described as clicking, popping, or crepitus (grating).
388:
680:), are also suggested to contribute to the development of TMD. Other parafunctional activities might include jaw thrusting, excessive gum chewing,
2233:
The highest prevalence of TMD (regardless of type) is in South
America at 47%, followed by Asia at 33%, Europe at 29%, and North America at 26%.
2099:
379:
6888:
6702:
2230:
Using the RDC/TMD criteria, TMD has a prevalence in the general population of 9.7% for group I, 11.4% for group IIa, and 2.6% for group IIIa.
7846:
1595:
1435:
Pain in muscles of mastication, the TMJ, or the periauricular area (around the ear), which is usually made worse by manipulation or function.
1289:
In those studies allowing images, imaging conducted by either arthrography or magnetic resonance reveals disc displacement without reduction.
1118:
The jaw deviates to the affected side during opening, and restricted mouth opening usually signifies that both TMJs are involved, but severe
7908:
725:
of TMD following whiplash injury, and that pTMD has a poorer response to treatment than TMD which has not developed in relation to trauma.
3249:
3091:
2906:
2602:
2380:
1636:
TMD can be difficult to manage, and since the disorder transcends the boundaries between several health-care disciplines β in particular,
6214:
Costen JB (October 1997). "A syndrome of ear and sinus symptoms dependent upon disturbed function of the temporomandibular joint. 1934".
1997:
1349:
Modern digitalised panoramic X-ray devices are capable to take TMJ images, which provides information about articular fossa and condyle.
2121:
1609:
US is commonly assessed in the differential diagnosis of alterations of glandular and neighbouring structures, such as the TMJ and the
1535:
and CBCT examinations are to assess the bony components of the TMJ, specifically the location and extent of any abnormalities present.
498:
TMJ dysfunction is commonly associated with symptoms affecting cervical spine dysfunction and altered head and cervical spine posture.
2077:. The reviewers also stated that there are ethical implications if occlusal adjustment was found to be ineffective in preventing TMD.
1620:
US assessment is also indicated where there is need to identify the correct position of the joint spaces for infiltrative procedures,
5943:
Laurence B (March 2012). "Acupuncture may be no more effective than sham acupuncture in treating temporomandibular joint disorders".
5620:
Miernik M, Wieckiewicz M, Paradowska A, Wieckiewicz W (SeptemberβOctober 2012). "Massage therapy in myofascial TMD pain management".
4160:
Alomar X, Medrano J, Cabratosa J, Clavero JA, Lorente M, Serra I, et al. (June 2007). "Anatomy of the temporomandibular joint".
6500:
3998:
Trovato F, Orlando B, Bosco M (2009). "Occlusal features and masticatory muscles activity. A review of electromyographic studies".
3043:
Luther F, Layton S, McDonald F (July 2010). McDonald F (ed.). "Orthodontics for treating temporomandibular joint (TMJ) disorders".
2554:
Guo C, Shi Z, Revington P (October 2009). Guo C (ed.). "Arthrocentesis and lavage for treating temporomandibular joint disorders".
969:
are not directly associated with the joint capsule. Together, these ligaments act to restrict the extreme movements of the joint.
8473:
7671:
7622:
4319:
3141:"Central sensitivity syndromes: mounting pathophysiologic evidence to link fibromyalgia with other common chronic pain disorders"
4730:
Petersson A (October 2010). "What you can and cannot see in TMJ imaging--an overview related to the RDC/TMD diagnostic system".
1049:
Each lateral pterygoid muscle is composed of 2 heads, the upper or superior head and the lower or inferior head. The lower head
3559:"Effectiveness of Manual Therapy and Therapeutic Exercise for Temporomandibular Disorders: Systematic Review and Meta-Analysis"
1895:
carried out in 2010 concluded that there was insufficient evidence to support or not to support the use of these drugs in TMD.
4084:
Miller JR, Burgess JA, Critchlow CW (2004). "Association between mandibular retrognathia and TMJ disorders in adult females".
1153:
Due to the proximity of the ear to the temporomandibular joint, TMJ pain can often be confused with ear pain. The pain may be
6087:
5696:
Crider A, Glaros AG, Gevirtz RN (December 2005). "Efficacy of biofeedback-based treatments for temporomandibular disorders".
5304:
4435:
4285:
4213:
3688:
3532:
3494:
3458:
3330:
2839:
2742:
2467:
1018:
944:(sliding) joint, and involves the condylar process of the mandible below, and the articular fossa (or glenoid fossa) of the
7484:
6337:
5739:
Hagandora CK, Almarza AJ (August 2012). "TMJ disc removal: comparison between pre-clinical studies and clinical findings".
5348:
Marbach JJ (August 1996). "Temporomandibular pain and dysfunction syndrome. History, physical examination, and treatment".
1822:
1042:
Elevation β Anterior and middle fibers of temporalis, the superficial and deep fibers of masseter and the medial pterygoid.
953:
of the TMJ lines the inside of the fibrous capsule apart from the articular surfaces and the disc. This membrane secretes
8156:
5263:
8508:
8498:
7273:
6757:
3793:
734:
not have TMD. Although occlusal features may affect observed electrical activity in masticatory muscles, there are no
4030:
Koh H, Robinson PG (April 2004). "Occlusal adjustment for treating and preventing temporomandibular joint disorders".
140:
between 20 and 40 years of age, and it is more common in females than males. TMD is the second most frequent cause of
8400:
7033:
5064:
Lewis EL, Dolwick MF, Abramowicz S, Reeder SL (October 2008). "Contemporary imaging of the temporomandibular joint".
4378:
3982:
3652:
3647:(2nd ed.). Edinburgh: Churchill Livingstone. pp. 8, 14, 30, 31, 33, 101, 104, 106, 291β295, 338, 339, 351.
2641:"Management of Temporomandibular Disorders. National Institutes of Health Technology Assessment Conference Statement"
1730:(also termed bite plates or intra-oral appliances) are often used by dentists to treat TMD. They are usually made of
20:
5649:"Effect of low-level laser therapy on pain levels in patients with temporomandibular disorders: a systematic review"
3392:
2773:"Research diagnostic criteria for temporomandibular disorders: a systematic review of axis I epidemiologic findings"
8375:
8312:
8307:
8189:
7617:
7597:
6509:
1776:
Ear canal inserts are also available, but no published peer-reviewed clinical trials have shown them to be useful.
1582:(US) imaging can be a useful alternative in assessing the position of the disc While having significant diagnostic
961:, also termed the lateral ligament, which really is a thickening of the lateral aspect of the fibrous capsule. The
362:
The preferred terms in medical publications is to an extent influenced by geographic location. For example, in the
5593:
Aggarwal A, Keluskar V (MarchβApril 2012). "Physiotherapy as an adjuvant therapy for treatment of TMJ disorders".
2512:
Cairns BE (May 2010). "Pathophysiology of TMD pain--basic mechanisms and their implications for pharmacotherapy".
1898:
In a subset of people with TMD who are not helped by either noninvasive and invasive treatments, long term use of
1199:
Report of pain or ache in the jaw, temples, face, preauricular area, or inside the ear at rest or during function;
1065:. The upper head originates from the infratemporal surface and the infratemporal crest of the greater wing of the
8221:
7858:
7312:
5498:
Schwartz M, Freund B (NovemberβDecember 2002). "Treatment of temporomandibular disorders with botulinum toxin".
4452:
1598:
morphology based on the findings done related to morphological alterations. However, with US, identification of
327:
disorder. It is hypothesized that there is a great deal of similarity between TMD and other pain syndromes like
8206:
8041:
4509:
1949:). Platelet-rich fibrin injection, alone or associated with arthrocentesis, can be considered a very suitable.
392:
66:
5024:
Hunter A, Kalathingal S (July 2013). "Diagnostic imaging for temporomandibular disorders and orofacial pain".
4320:"Manual therapy of the mandibular accessory ligaments for the management of temporomandibular joint disorders"
400:"Temporomandibular joint-pain-dysfunction syndrome" listed in turn under "Temporomandibular joint disorders" (
8046:
1688:
1264:
Absence of joint sound or presence of joint sounds not meeting criteria for disc displacement with reduction.
753:
1699:. It has been suggested that TMD involves increased sensitivity to external stimuli leading to an increased
990:
7909:
7570:
7179:
6883:
6868:
6806:
6752:
6675:
6493:
5546:"An evidence-based review of botulinum toxin (Botox) applications in non-cosmetic head and neck conditions"
1962:
1672:
1563:
295:
TMD is considered by some to be one of the 4 major symptom complexes in chronic orofacial pain, along with
129:
1039:
Retraction β Posterior fibers of temporalis (and the digastric and geniohyoid muscles to a lesser extent).
634:
hyperactivity has also been shown in people with TMD whilst taking examinations or watching horror films.
8098:
8061:
7791:
7072:
6984:
5981:
DeVocht JW (March 2006). "History and overview of theories and methods of chiropractic: a counterpoint".
5425:
Bouloux GF (July 2011). "Use of opioids in long-term management of temporomandibular joint dysfunction".
2640:
2254:
2116:
scans now receive less attention. These techniques are reserved for the most difficult cases where other
1769:
1587:
1583:
809:
6103:
List T, Axelsson S (May 2010). "Management of TMD: evidence from systematic reviews and meta-analyses".
2124:
recommends a conservative/non-surgical approach first. Only 20% of patients need to proceed to surgery.
1475:
D. Headache resolves within 3 months, and does not recur, after successful treatment of the TMJ disorder
913:
Sagittal TMJ cross-section showing articular eminence, articular disc, and upper and lower joint spaces.
8108:
8056:
7863:
7796:
7565:
7065:
7060:
7011:
2189:
1700:
1669:, may be important in the treatment of TMD, which often tends to attempt to address the pain directly.
1547:
958:
630:
19:
This article is about the syndrome with joint pain. For the range of diseases affecting the joint, see
8113:
7831:
7735:
7206:
6670:
6338:"Orofacial Pain is Now the 12th ADA-Recognized Dental Specialty - American Academy of Orofacial Pain"
2113:
1858:
1739:
be used for about 2β3 months. It is more complicated to construct than other types of splint since a
1458:
C. Evidence that pain can be attributed to the TMJ disorder, based on at least one of the following:
1400:
1371:
Pain is the most common reason for people with TMD to seek medical advice. Joint noises may require
966:
405:
2956:"The relationship of whiplash injury and temporomandibular disorders: a narrative literature review"
1134:
may occur. All these factors may lead to a further limitation of jaw movement and increase in pain.
8420:
8199:
8184:
7880:
7836:
7781:
7654:
7612:
7380:
7226:
6409:
1888:
1873:
1139:
1084:
962:
735:
722:
598:
561:
332:
8253:
4570:
Anderson GC, Gonzalez YM, Ohrbach R, Truelove EL, Sommers E, Look JO, Schiffman EL (Winter 2010).
3414:
2272:
1602:
in individuals with inflammatory conditions associated with pain is possible and confirmed by MRI
8317:
8118:
8083:
7776:
7580:
7360:
7201:
7147:
7077:
6999:
6979:
6966:
6943:
6486:
4970:
Alkhader M, Ohbayashi N, Tetsumura A, Nakamura S, Okochi K, Momin MA, Kurabayashi T (July 2010).
2433:
2168:
2009:
1054:
931:
804:, and also rapidly increases just before menstruation and rapidly decreases during menstruation.
98:
3415:"International Statistical Classification of Diseases and Related Health Problems 10th Revision"
3008:
1061:
at a depression on the neck of mandibular condyle, just below the articular surface, termed the
8463:
8430:
8103:
8093:
8088:
8030:
7957:
7913:
7809:
7804:
7590:
7420:
7415:
7390:
7236:
7167:
6994:
6903:
6821:
6548:
5221:
4427:
2340:
Shi Z, Guo C, Awad M (2003). Shi Z (ed.). "Hyaluronate for temporomandibular joint disorders".
2117:
1412:
1380:
1222:
Maximum assisted opening (passive stretch) 5 mm greater than pain-free unassisted opening.
978:
661:
594:
296:
94:
6811:
6449:
4370:
2831:
2127:
Examples of surgical procedures that are used in TMD, some more commonly than others, include
8272:
8174:
7786:
7664:
7526:
7485:
7285:
7087:
7021:
6948:
6373:
5916:
Cho SH, Whang WW (2010). "Acupuncture for temporomandibular disorders: a systematic review".
2771:
Manfredini D, Guarda-Nardini L, Winocur E, Piccotti F, Ahlberg J, Lobbezoo F (October 2011).
2057:
1684:
1558:
MRI provides evaluation of pathology such as necrosis and oedema all without any exposure to
1363:
Dynamics of temporomandibular joint during voluntary mouth opening and closing visualized by
702:
672:
Other parafunctional habits such as pen chewing, lip and cheek biting (which may manifest as
336:
312:
6262:
Perry HT (January 1995). "Temporomandibular joint dysfunction: from Costen to the present".
4419:
4362:
3704:
2823:
136:
or others. Most sources agree that no irreversible treatment should be carried out for TMD.
8370:
8271:
8009:
7994:
7560:
7493:
7099:
6831:
5647:
Maia ML, Bonjardim LR, de Souza
Siqueira Quintans J, Ribeiro MA, Maia LG, Conti PC (2012).
4535:
2061:
1862:
1625:
1408:
1384:
1170:
849:
652:
578:
300:
1261:
Contralateral excursion 7 mm or uncorrected deviation to ipsilateral side on opening;
818:
8:
8425:
8161:
8141:
8131:
8004:
7937:
7819:
7814:
7740:
7639:
7292:
7216:
7055:
7004:
6953:
6933:
6846:
6836:
6762:
6737:
6595:
6398:
5819:"Limited evidence that acupuncture is effective for treating temporomandibular disorders"
4572:"The Research Diagnostic Criteria for Temporomandibular Disorders. VI: future directions"
2735:
Essential dental handbook : clinical and practice management advice from the experts
1058:
1004:
713:
673:
418:
320:
304:
276:
6174:
6139:
5115:
4832:
Klatkiewicz T, GawrioΕek K, Pobudek
Radzikowska M, Czajka-Jakubowska A (February 2018).
4831:
4393:
Contemporary Oral and Maxillofacial Surgery fifth edition; Hupp, ellis, and tucker. 2008
4072:
2701:
2666:
1452:
A. Recurrent pain in one or more regions of the head or face fulfilling criteria C and D
1304:
Pain in one or both joint sites (lateral pole or posterior attachment) during palpation;
8504:
Pathology of temporomandibular joints, muscles of mastication and associated structures
8468:
8415:
8390:
8322:
8126:
8051:
7942:
7890:
7851:
7548:
7464:
7395:
7104:
6928:
6908:
6861:
6747:
6692:
6655:
6645:
6630:
6560:
6403:
6319:
6239:
6052:
6025:
6006:
5994:
5893:
5764:
5721:
5673:
5648:
5570:
5545:
5523:
4996:
4971:
4909:
4882:
4858:
4833:
4802:
4775:
4588:
4571:
4254:
4202:
4097:
4055:
3842:
3817:
3766:
3583:
3558:
3266:
3258:
3222:
3165:
3140:
3108:
3100:
3064:
2980:
2955:
2923:
2915:
2879:
2619:
2611:
2575:
2397:
2389:
2024:. MT has been used to restore normal range of motion, promoting circulation, stimulate
1844:
1559:
1388:
814:
789:
698:
677:
238:
5400:
5361:
4339:
8166:
7755:
7720:
7694:
7553:
7449:
7307:
7231:
6938:
6878:
6841:
6816:
6665:
6543:
6538:
6420:
6311:
6271:
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6179:
6161:
6120:
6116:
6083:
6057:
5998:
5960:
5925:
5885:
5840:
5799:
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5713:
5678:
5629:
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5575:
5515:
5511:
5480:
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5001:
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4743:
4712:
4676:
4636:
4593:
4501:
4467:
4431:
4420:
4374:
4363:
4331:
4281:
4246:
4209:
4177:
4142:
4137:
4120:
4101:
4047:
4043:
4007:
3978:
3940:
3909:
3874:
3847:
3789:
3758:
3684:
3648:
3588:
3528:
3490:
3454:
3326:
3241:
3214:
3170:
3083:
3056:
2985:
2898:
2871:
2835:
2824:
2795:
2738:
2706:
2688:
2594:
2567:
2529:
2525:
2473:
2463:
2372:
2353:
2319:
2136:
1945:. Steroids and other medications are sometimes injected directly into the joint (See
1892:
1847:
1744:
1666:
1649:
950:
761:
626:
622:
468:
282:
255:
61:
6460:
6323:
6243:
6010:
5897:
5768:
5664:
5527:
4258:
4059:
3770:
3226:
2883:
2579:
1206:
At least one of the painful sites must be on the same side as the complaint of pain.
8136:
7771:
7761:
7725:
7634:
7385:
7324:
7258:
7248:
7196:
7094:
6989:
6826:
6478:
6303:
6223:
6169:
6151:
6112:
6047:
6037:
5990:
5952:
5877:
5830:
5791:
5748:
5725:
5705:
5668:
5660:
5565:
5557:
5507:
5472:
5434:
5396:
5357:
5233:
5194:
5153:
5111:
5073:
5033:
4991:
4983:
4941:
4904:
4894:
4853:
4845:
4797:
4787:
4739:
4704:
4668:
4628:
4583:
4550:
4238:
4169:
4132:
4093:
4039:
3901:
3837:
3829:
3816:
Shetty S, Pitti V, Satish Babu CL, Surendra Kumar GP, Deepthi BC (September 2010).
3750:
3578:
3570:
3237:
3233:
3210:
3206:
3160:
3152:
3079:
3075:
3068:
3052:
3048:
2975:
2967:
2894:
2890:
2867:
2863:
2787:
2696:
2678:
2590:
2586:
2563:
2559:
2521:
2368:
2364:
2345:
2315:
2311:
2242:
2223:
2219:
1977:
1934:
1731:
1692:
1645:
1416:
1286:
Presence of joint sounds not meeting criteria for disc displacement with reduction;
1162:
1050:
941:
706:
610:
605:
and skeletal activity and by reduced inhibition via the descending pathways of the
514:
417:
It has been suggested that TMD may develop following physical trauma, particularly
324:
5198:
4834:"Ultrasonography in the Diagnosis of Temporomandibular Disorders: A Meta-Analysis"
4708:
4632:
3905:
2791:
1675:(CBT) has been used in TMD and has been shown to be efficacious by meta analyses.
8292:
8078:
7873:
7766:
7602:
7521:
7501:
7425:
7410:
7280:
7184:
7152:
7123:
7045:
6971:
6767:
6650:
6640:
6585:
6570:
6414:
5881:
5544:
Persaud R, Garas G, Silva S, Stamatoglou C, Chatrath P, Patel K (February 2013).
4883:"MRI and CBCT image registration of temporomandibular joint: a systematic review"
3557:
Armijo-Olivo S, Pitance L, Singh V, Neto F, Thie N, Michelotti A (January 2016).
2194:
1952:
1903:
1870:
1818:
1814:
1727:
1610:
1062:
797:
705:, sports injuries, interpersonal violence, or during dental treatment, (such as
542:
Sensation of malocclusion (feeling that the teeth do not meet together properly).
518:
509:(the back of the head), or the forehead; or other types of facial pain including
316:
308:
110:
6466:
6463:
6138:
ZieliΕski, Grzegorz; PajΔ
k-ZieliΕska, Beata; Ginszt, MichaΕ (28 February 2024).
5956:
5795:
5237:
4792:
4555:
2665:
ZieliΕski, Grzegorz; PajΔ
k-ZieliΕska, Beata; Ginszt, MichaΕ (28 February 2024).
42:
Temporomandibular joint dysfunction syndrome, temporomandibular disorder, others
8458:
8410:
8380:
8248:
8179:
8146:
7868:
7607:
7341:
7221:
7016:
6801:
6614:
6425:
6307:
6227:
6202:
6197:
5476:
5438:
5157:
5077:
5037:
4173:
3928:
2128:
2036:
reproducible results. High quality trials with larger sample sizes are needed.
2025:
2021:
1806:
1790:
1757:
1621:
1614:
1591:
1567:
1404:
1280:
Passive stretch increases opening by 5 mm over maximum unassisted opening;
1258:
Passive stretch increases opening by 4 mm over maximum unassisted opening;
954:
777:
574:
436:
363:
141:
102:
6388:
5709:
5646:
5270:
4899:
3833:
3754:
3453:(5th ed.). St. Louis, Missouri: Mosby. pp. 191, 204, 233, 234, 227.
3156:
2971:
2349:
899:
Left TMJ, medial view, showing sphenomandibular and stylomandibular ligaments.
8492:
8360:
8238:
8066:
7885:
7649:
7629:
7538:
7405:
7365:
7162:
6923:
6898:
6873:
6851:
6635:
6625:
6590:
6165:
5752:
5561:
4776:"Diagnosis of temporomandibular joint disorders: indication of imaging exams"
2692:
1973:
1957:
1881:
1877:
1662:
1364:
1154:
1066:
945:
765:
606:
70:
5389:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
5187:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
4987:
4945:
4697:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
4672:
4621:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
4242:
3894:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
2780:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
1711:
120:
is taken to mean any disorder that affects the temporomandibular joint, and
8211:
7987:
7982:
7967:
7947:
7917:
7750:
7459:
7400:
7331:
7253:
7243:
7211:
7174:
7135:
7127:
6742:
6697:
6682:
6580:
6575:
6183:
6124:
6061:
6042:
6002:
5964:
5929:
5889:
5844:
5835:
5818:
5803:
5760:
5717:
5682:
5633:
5606:
5579:
5519:
5484:
5446:
5334:
5245:
5206:
5165:
5123:
5085:
5045:
5005:
4953:
4918:
4867:
4811:
4751:
4716:
4680:
4640:
4597:
4505:
4471:
4335:
4250:
4181:
4146:
4105:
4051:
4011:
3944:
3913:
3851:
3762:
3645:
Oral and maxillofacial medicine : the basis of diagnosis and treatment
3592:
3245:
3218:
3174:
3087:
3060:
2989:
2902:
2875:
2799:
2710:
2598:
2571:
2533:
2477:
2376:
2357:
2323:
2246:
1392:
1372:
1203:
submandibular region, lateral pterygoid area, and tendon of the temporalis;
862:
387:"Headache or facial pain attributed to temporomandibular joint disorder." (
328:
113:; this is because the symptoms can become chronic and difficult to manage.
8347:
6315:
6275:
6235:
5408:
5369:
4774:
Ferreira LA, Grossmann E, Januzzi E, de Paula MV, Carvalho AC (May 2016).
4536:"Real-time magnetic resonance imaging of temporomandibular joint dynamics"
3878:
3705:"Definitions of "Arthrosis" from various medical and popular dictionaries"
3255:. If this is an intentional citation to a retracted paper, please replace
3097:. If this is an intentional citation to a retracted paper, please replace
2912:. If this is an intentional citation to a retracted paper, please replace
2608:. If this is an intentional citation to a retracted paper, please replace
2386:. If this is an intentional citation to a retracted paper, please replace
2222:
are more likely to be affected by TMD, and at an earlier age, than female
1617:, TMD, myofascial and nerve pain, and other pain of the orofacial region.
8405:
8395:
8385:
8302:
8297:
8228:
7302:
7263:
7082:
6958:
6918:
6786:
6707:
6687:
6444:
6140:"A Meta-Analysis of the Global Prevalence of Temporomandibular Disorders"
6080:
Trick or treatment : the undeniable facts about alternative medicine
3574:
3389:"2nd Edition International Classification of Headache Disorders (ICHD-2)"
2667:"A Meta-Analysis of the Global Prevalence of Temporomandibular Disorders"
2215:
2176:
2172:
2152:
2132:
2053:
2040:
1923:
1866:
1740:
1376:
1165:. Treatment of TMD may then significantly reduce symptoms of otalgia and
773:
681:
478:
The three classically described, cardinal signs and symptoms of TMD are:
208:
106:
6356:
6156:
4849:
2772:
2683:
1613:. Symptoms of sialendenitis and sialothiasis cases can be confused with
1594:. Moreover, it is not accurate enough for the diagnosis of cortical and
1099:
Generally, degenerative joint changes are associated with greater pain.
573:
The general term "degenerative joint disease" refers to arthritis (both
8365:
8151:
7977:
7745:
7575:
7516:
7454:
7444:
7437:
7432:
7370:
7353:
7297:
7268:
7189:
7050:
7028:
6913:
6893:
5619:
4881:
Al-Saleh MA, Alsufyani NA, Saltaji H, Jaremko JL, Major PW (May 2016).
4121:"Diving dentistry: a review of the dental implications of scuba diving"
2770:
2005:
1830:
1810:
1794:
1696:
1579:
1488:
Assess the integrity of anatomical structures in suspicion of disorders
717:
694:
582:
422:
261:
5458:
5456:
1461:
pain is precipitated by jaw movements or chewing of hard or tough food
8233:
8216:
7952:
7730:
7533:
7157:
7040:
6660:
6555:
6533:
6455:
2001:
1989:
1927:
1915:
1851:
1838:
1826:
1786:
1641:
1637:
1396:
1324:
Either coarse crepitus in the joint or radiologic signs of arthrosis.
1311:
For a diagnoses of simple arthralgia, coarse crepitus must be absent.
937:
805:
801:
757:
483:
460:
344:
340:
270:
265:
145:
133:
6024:
Bronfort G, Haas M, Evans R, Leininger B, Triano J (February 2010).
5384:
4453:"Temporomandibular disorders: referred cranio-cervico-facial clinic"
3815:
1902:
analgesics has been suggested, although these drugs carry a risk of
1337:
Either coarse crepitus in the joint or radiologic signs of arthrosis
8243:
8194:
7962:
7715:
7696:
7676:
7497:
7375:
7319:
6565:
5453:
1985:
1942:
1919:
1911:
1907:
1834:
1802:
1798:
1743:
record is required and significantly more skill on the part of the
1678:
1599:
1166:
1131:
792:
769:
657:
614:
533:
527:
510:
356:
192:
16:
Disorders of the muscles and joints connecting the jaw to the skull
4969:
4271:
2305:
1956:
Botulinum toxin causes temporary muscular paralysis by inhibiting
1555:
neural tissues, which may produce orofacial pain when compressed.
1269:
IIc. Disc displacement without reduction, without limited opening:
8329:
8287:
7972:
7932:
7826:
7700:
7489:
6856:
6082:(1st American ed.). New York: W.W. Norton. pp. 149β90.
5222:"Ultrasound-guided arthrocentesis of the temporomandibular joint"
3354:
3352:
3350:
3348:
3346:
3344:
3342:
2157:
2105:
2074:
1938:
1719:
1532:
1158:
1119:
646:
506:
456:
204:
186:
6294:
Michael LA (October 1997). "Jaws revisited: Costen's syndrome".
4773:
4274:"Anatomy, Pathology, and Imaging of the Temporomandibular Joint"
2218:
than females without TMD. It has also been reported that female
1821:), and others. Analgesics that have been studied in TMD include
8071:
7543:
7131:
6726:
6383:
6368:
4880:
4569:
4204:
Gray's anatomy : the anatomical basis of clinical practice
1899:
1345:
602:
452:
448:
401:
6137:
3740:
3339:
2664:
1247:
IIb. Disc displacement without reduction with limited opening:
5866:
4658:
4159:
2460:
Temporomandibular Disorders: Priorities for Research and Care
2257:
officially recognized orofacial pain as a dental speciality.
2043:
to reduce nighttime clenching experience a reduction in TMD.
1891:
being conducted on these commonly used medications for TMD a
1161:(earache). Conversely, TMD is an important possible cause of
788:
Since females are more often affected by TMD than males, the
560:
In people with TMD, it has been shown that the lower head of
472:
48:
5543:
5063:
4208:(39th ed.). Edinburgh: Elsevier Churchill Livingstone.
3556:
1857:
Other drugs that have been described for use in TMD include
1715:
A lower, full coverage occlusal splint after 8 years in use.
1655:
6026:"Effectiveness of manual therapies: the UK evidence report"
4617:
4369:(3rd ed.). Edinburgh: Churchill Livingstone. pp.
2954:
Fernandez CE, Amiri A, Jaime J, Delaney P (December 2009).
1455:
B. X-ray, MRI or bone scintigraphy demonstrate TMJ disorder
1431:
McNeill 1997 described TMD diagnostic criteria as follows:
464:
251:
90:
6023:
5385:"Pharmacologic treatments for temporomandibular disorders"
5297:
Handbook of evidence-based practice in clinical psychology
4693:
4450:
4272:
Westesson PL, Otonari-Yamamoto M, Sano T, Okano T (2011).
4229:
Davies S, Gray RM (September 2001). "What is occlusion?".
3489:(3rd ed.). Ames, IA: Wiley-Blackwell. pp. 1β15.
2953:
2857:
2039:
There is some evidence that some people who use nighttime
1996:
Occasionally physiotherapy for TMD may include the use of
1383:
is with degenerative joint disease (e.g. osteoarthritis),
907:
893:
879:
597:(anxiety, depression, anger) may increase pain by causing
6522:
2109:
5319:
4426:(5th ed.). St. Louis, MO: Mosby Elsevier. pp.
4317:
3003:
3001:
2999:
2462:. Washington (DC): National Academies Press (US). 2020.
2275:, National Institute of Dental and Craniofacial Research
1438:
Asymmetric mandibular movement with or without clicking.
1274:
History of significant limitation of mandibular opening;
5465:
International Journal of Oral and Maxillofacial Surgery
5226:
The British Journal of Oral & Maxillofacial Surgery
5146:
International Journal of Oral and Maxillofacial Surgery
3451:
Management of temporomandibular disorders and occlusion
2821:
1965:, which lasts until the effects of the botox wear off.
5264:"Temporomandibular (Jaw) Joint Diseases and Disorders"
5143:
4451:
RamΓrez LM, Sandoval GP, Ballesteros LE (April 2005).
4083:
3525:
CawsonΕ essentials of oral pathology and oral medicine
2830:(2nd ed.). Philadelphia: W.B. Saunders. pp.
2432:
Joseph Rios (22 February 2017). Robert A. Egan (ed.).
2081:
between orthodontics and TMD concluded the following:
1470:
tenderness of the joint capsule(s) of one or both TMJs
402:
International Classification of Diseases 10th revision
368:
National Institute of Dental and Craniofacial Research
4318:
Cuccia AM, Caradonna C, Caradonna D (February 2011).
4073:
https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0013523/
3977:. Oxford: Oxford University Press. pp. 342β351.
3783:
3320:
3200:
2996:
1294:
Group III: arthralgia, osteoarthritis, osteoarthrosis
817:
in the trigeminal nerve, muscle reflexes to pain and
6508:
6346:
5101:
3042:
3009:"Temporomandibular Disorders (TMD) Policy Statement"
2427:
2425:
2423:
2421:
2419:
2417:
2415:
2413:
2411:
1113:
5695:
5261:
5219:
4533:
4324:
The Journal of the American Osteopathic Association
3997:
3138:
2135:, meniscectomy, disc repositioning, condylotomy or
1542:
1219:
Pain-free unassisted mandibular opening 40 mm;
760:with regards pain sensitivity. COMT (together with
618:sensation that the teeth are not fitting properly.
7922:Jaw joints, chewing muscles and bite abnormalities
5183:
4201:
3891:
3527:(7th ed.). Edinburgh: Churchill Livingstone.
2822:Neville BW, Damm DD, Allen CA, Bouquot JE (2002).
2766:
2764:
2762:
2760:
2758:
2756:
2754:
2301:
1157:in around half of all patients and experienced as
693:This may occur during dental treatment, with oral
389:International Classification of Headache Disorders
6785:
6296:The Annals of Otology, Rhinology, and Laryngology
6216:The Annals of Otology, Rhinology, and Laryngology
5862:
5860:
5858:
5856:
5854:
5023:
4931:
4887:Journal of OtolaryngologyβHead & Neck Surgery
4195:
4193:
4191:
3864:
3788:(5th ed.). Oxford: Oxford University Press.
3522:
2949:
2947:
2945:
2943:
2941:
2939:
2937:
2408:
2299:
2297:
2295:
2293:
2291:
2289:
2287:
2285:
2283:
2281:
8490:
7122:
5738:
5592:
3972:
3968:
3966:
3964:
3962:
3960:
3958:
3956:
3954:
3681:Burket's oral medicine diagnosis & treatment
3391:. International Headache Society. Archived from
3316:
3314:
3312:
3310:
3308:
3306:
3304:
3302:
3300:
2853:
2851:
1467:noise from one or both TMJs during jaw movements
712:It has been proposed that a link exists between
8277:Teeth, jaws, tongue and associated soft tissues
6289:
6287:
6285:
5976:
5974:
5539:
5537:
5420:
5418:
5220:Dayisoylu EH, Cifci E, Uckan S (October 2013).
5059:
5057:
5055:
4417:
3885:
3736:
3734:
3732:
3730:
3728:
3726:
3724:
3722:
3638:
3636:
3634:
3632:
3630:
3628:
3626:
3624:
3622:
3298:
3296:
3294:
3292:
3290:
3288:
3286:
3284:
3282:
3280:
3139:Kindler LL, Bennett RM, Jones KD (March 2011).
3134:
3132:
3130:
3128:
3126:
3124:
3122:
2817:
2815:
2813:
2811:
2809:
2751:
2553:
2100:Surgery for temporomandibular joint dysfunction
1946:
1522:
380:International Association for the Study of Pain
6889:Hereditary benign intraepithelial dyskeratosis
5851:
5781:
5732:
5622:Advances in Clinical and Experimental Medicine
5497:
4487:"Atypical facial pain--a diagnostic challenge"
4313:
4311:
4309:
4188:
3811:
3809:
3807:
3805:
3777:
3678:
3620:
3618:
3616:
3614:
3612:
3610:
3608:
3606:
3604:
3602:
3518:
3516:
3514:
3512:
3510:
3508:
3506:
3480:
3478:
3476:
3474:
3472:
3470:
3444:
3442:
3440:
3438:
3436:
3434:
3432:
3196:
3194:
3192:
3190:
3188:
3186:
3184:
3038:
3036:
3034:
3032:
3030:
3028:
3026:
2934:
2507:
2278:
1494:Monitoring and staging the progress of disease
350:
7847:Neuralgia-inducing cavitational osteonecrosis
6494:
6257:
6255:
6253:
6073:
6071:
6017:
5945:The Journal of Evidence-Based Dental Practice
5586:
5491:
5462:
5294:
4563:
4460:Medicina Oral, Patologia Oral y Cirugia Bucal
3951:
3920:
3858:
3674:
3672:
3670:
3668:
3666:
3664:
2848:
2728:
2726:
2724:
2722:
2720:
2505:
2503:
2501:
2499:
2497:
2495:
2493:
2491:
2489:
2487:
1252:History of significant limitation in opening;
568:
355:Frequently, TMD has been treated as a single
235:Hypomobility of the disc (adhesions or scars)
6282:
6264:Annals of the Academy of Medicine, Singapore
6102:
5971:
5613:
5534:
5415:
5341:
5052:
4478:
4444:
4413:
4411:
4409:
4407:
4405:
4403:
4401:
4399:
4118:
3991:
3719:
3321:Wassell R, Naru A, Steele J, Nohl F (2008).
3277:
3119:
2806:
1578:Where internal TMJ disorders are concerned,
6207:
5911:
5909:
5907:
5376:
5288:
4422:Contemporary oral and maxillofacial surgery
4306:
4280:(5th ed.). St. Louis: Mosby Elsevier.
4222:
4153:
4029:
4025:
4023:
4021:
3802:
3683:(10th ed.). Hamilton, Ont: BC Decker.
3599:
3503:
3467:
3429:
3203:The Cochrane Database of Systematic Reviews
3181:
3045:The Cochrane Database of Systematic Reviews
3023:
2860:The Cochrane Database of Systematic Reviews
2556:The Cochrane Database of Systematic Reviews
2431:
2342:The Cochrane Database of Systematic Reviews
2308:The Cochrane Database of Systematic Reviews
1998:transcutaneous electrical nerve stimulation
1976:(physical therapy) is sometimes used as an
925:
885:Left temporomandibular joint, lateral view.
800:, estrogen levels fluctuate rapidly during
6501:
6487:
6250:
6077:
6068:
5983:Clinical Orthopaedics and Related Research
5350:Rheumatic Disease Clinics of North America
4354:
4228:
4112:
3661:
3269:|...|intentional=yes}}
3111:|...|intentional=yes}}
3011:. American Association for Dental Research
2926:|...|intentional=yes}}
2717:
2622:|...|intentional=yes}}
2549:
2547:
2545:
2543:
2484:
2400:|...|intentional=yes}}
2339:
2335:
2333:
2122:American Society of Maxillofacial Surgeons
1036:Protrusion β Lateral and medial pterygoid.
629:, and these could be considered important
524:Pain elsewhere, such as the teeth or neck.
47:
6173:
6155:
6096:
6051:
6041:
5834:
5775:
5672:
5640:
5569:
5427:Journal of Oral and Maxillofacial Surgery
4995:
4908:
4898:
4857:
4801:
4791:
4729:
4587:
4554:
4527:
4396:
4199:
4136:
3841:
3784:Tyldesley WR, Field A, Longman L (2003).
3582:
3383:
3381:
3164:
2979:
2737:. Tulsa, OK: PennWell. pp. 251β309.
2700:
2682:
2635:
2633:
1906:and other side effects. Examples include
1656:Psychosocial and behavioral interventions
1464:reduced range of or irregular jaw opening
1211:Ib. Myofascial pain with limited opening:
1072:
997:Left medial and lateral pterygoid muscles
972:
920:
5942:
5915:
5904:
5698:Applied Psychophysiology and Biofeedback
4780:Brazilian Journal of Otorhinolaryngology
4265:
4018:
3926:
3325:. London: Quintessence. pp. 73β84.
1723:An upper, full coverage occlusal splint.
1718:
1710:
1352:
1344:
824:
740:
412:
232:Disc displacement (internal derangement)
97:(the muscles that move the jaw) and the
8474:Oral manifestations of systemic disease
7623:Acute necrotizing ulcerative gingivitis
6293:
5980:
5424:
5347:
5257:
5255:
3822:Journal of Indian Prosthodontic Society
2540:
2330:
2142:
2104:Attempts in the last decade to develop
1513:
1444:Pain present for a minimum of 3 months.
589:
307:. TMD has been considered as a type of
8491:
7660:As a manifestation of systemic disease
6213:
5382:
5299:. Hoboken, NJ: Wiley. pp. 594β5.
4654:
4652:
4650:
4534:Zhang S, Gersdorff N, Frahm J (2011).
3865:De Meyer MD, De Boever JA (1997). "".
3642:
3552:
3550:
3548:
3546:
3544:
3523:Cawson RA, Odell EW, Porter S (2002).
3484:
3448:
3378:
2630:
2511:
2046:
1422:
1277:Maximum unassisted opening 35 mm;
1255:Maximum unassisted opening 35 mm;
1232:IIa. Disc displacement with reduction:
505:Headache (possibly), e.g. pain in the
8447:
8346:
8270:
8028:
7907:
7693:
7483:
7121:
6784:
6724:
6612:
6520:
6482:
6261:
5179:
5177:
5175:
5139:
5137:
5135:
5133:
5097:
5095:
5019:
5017:
5015:
4965:
4963:
4827:
4825:
4823:
4821:
4769:
4767:
4765:
4763:
4761:
4613:
4611:
4609:
4607:
4484:
4365:Clinical problem solving in dentistry
4360:
4119:Zadik Y, Drucker S (September 2011).
3973:Kerawala C, Newlands C, eds. (2010).
3487:Manual of temporomandibular disorders
2732:
1823:non-steroidal anti-inflammatory drugs
756:(COMT) which may produce 3 different
442:
7506:Gums and tooth-supporting structures
5816:
5252:
5104:Ultrasound in Medicine & Biology
4418:Hupp JR, Ellis E, Tucker MR (2008).
1652:pain medications may be prescribed.
1504:
1497:Determining the effects of treatment
1182:RDC/TMD criteria, axis I diagnoses.
1145:
1025:Left masseter muscle (red highlight)
555:
319:disorder. It has also been called a
8157:Papillary cystadenoma lymphomatosum
8029:
8000:Temporomandibular joint dysfunction
5116:10.1016/j.ultrasmedbio.2006.02.1401
4647:
3929:"Temporomandibular joint disorders"
3541:
1570:foreign bodies and pregnant women.
1491:Staging the extent of any pathology
1441:Limitation of mandibular movements.
1334:Absence of all signs of arthralgia;
783:
728:
665:may be no pain at all upon waking.
122:temporomandibular joint dysfunction
79:Temporomandibular joint dysfunction
34:Temporomandibular joint dysfunction
13:
7274:Maxillary lateral incisor agenesis
6758:Inflammatory papillary hyperplasia
5995:10.1097/01.blo.0000203460.89887.8d
5172:
5130:
5092:
5012:
4960:
4818:
4758:
4604:
4162:Seminars in Ultrasound, CT and MRI
4098:10.1111/j.1752-7325.2004.tb02746.x
4086:Journal of Public Health Dentistry
2826:Oral & maxillofacial pathology
1479:
1283:Contralateral excursion 7 mm;
1102:
869:
746:
14:
8520:
1216:Myofascial pain as defined in Ia;
1114:Limitation of mandibular movement
151:
21:Temporomandibular joint pathology
8376:Cutaneous sinus of dental origin
8313:Obesity hypoventilation syndrome
8308:Central hypoventilation syndrome
8190:Carcinoma ex pleomorphic adenoma
7618:Necrotizing periodontal diseases
7598:Hereditary gingival fibromatosis
6510:Oral and maxillofacial pathology
6117:10.1111/j.1365-2842.2010.02089.x
5512:10.1097/00002508-200211001-00013
4744:10.1111/j.1365-2842.2010.02108.x
4543:The Open Medical Imaging Journal
4138:10.1111/j.1834-7819.2011.01340.x
4044:10.1046/j.1365-2842.2003.01257.x
3867:Revue Belge de MΓ©decine Dentaire
2960:Journal of Chiropractic Medicine
2526:10.1111/j.1365-2842.2010.02074.x
1968:
1543:Magnetic resonance imaging (MRI)
1329:IIIc. Osteoarthrosis of the TMJ:
1316:IIIb. Osteoarthritis of the TMJ:
1053:from the lateral surface of the
1017:
1003:
989:
906:
892:
878:
201:Myofascial pain and fibromyalgia
8222:Chronic sclerosing sialadenitis
7859:Osteoporotic bone marrow defect
7313:Keratocystic odontogenic tumour
6330:
6190:
6131:
5936:
5810:
5689:
5665:10.1590/S1678-77572012000600002
5653:Journal of Applied Oral Science
5313:
5213:
5066:Dental Clinics of North America
5026:Dental Clinics of North America
4925:
4874:
4723:
4687:
4387:
4276:. In Som PM, Curtin HD (eds.).
4077:
4066:
3697:
3407:
2200:
2188:It has been suggested that the
2163:
1077:
764:) is involved in breaking down
89:) is an umbrella term covering
8207:Sclerosing polycystic adenosis
8042:Benign lymphoepithelial lesion
6105:Journal of Oral Rehabilitation
4976:Dento Maxillo Facial Radiology
4934:Dento Maxillo Facial Radiology
4732:Journal of Oral Rehabilitation
4661:Dento Maxillo Facial Radiology
4032:Journal of Oral Rehabilitation
3975:Oral and maxillofacial surgery
3818:"Bruxism: a literature review"
3679:Greenberg MS, Glick M (2003).
3238:10.1002/14651858.CD002778.pub3
3211:10.1002/14651858.CD002778.pub2
3080:10.1002/14651858.CD006541.pub3
3053:10.1002/14651858.CD006541.pub2
2895:10.1002/14651858.CD008456.pub3
2868:10.1002/14651858.CD008456.pub2
2658:
2591:10.1002/14651858.CD004973.pub3
2564:10.1002/14651858.CD004973.pub2
2514:Journal of Oral Rehabilitation
2452:
2369:10.1002/14651858.CD002970.pub2
2316:10.1002/14651858.CD004715.pub2
2266:
2147:
2004:. Others recommend the use of
1321:Arthralgia as defined in IIIa;
429:
393:International Headache Society
101:(the joints which connect the
67:Oral and maxillofacial surgery
1:
8401:MelkerssonβRosenthal syndrome
8350:Soft tissues around the mouth
8047:Ectopic salivary gland tissue
6030:Chiropractic & Osteopathy
5401:10.1016/S1079-2104(97)90104-9
5362:10.1016/S0889-857X(05)70283-0
5199:10.1016/j.tripleo.2011.02.020
4709:10.1016/j.tripleo.2008.03.021
4633:10.1016/j.tripleo.2006.02.001
3927:Buescher JJ (November 2007).
3906:10.1016/j.tripleo.2010.02.013
2792:10.1016/j.tripleo.2011.04.021
2434:"Temporomandibular Disorders"
2260:
1779:
1689:progressive muscle relaxation
1631:
1573:
1415:, deafferentation pains, and
808:females who are treated with
754:catechol-O-methyl transferase
7571:Gingival cyst of the newborn
7180:Failure of eruption of teeth
6884:Hand, foot and mouth disease
6869:Focal epithelial hyperplasia
6807:Angina bullosa haemorrhagica
6753:Palatal cysts of the newborn
6676:Transient lingual papillitis
6144:Journal of Clinical Medicine
5882:10.1097/AJP.0b013e3181e2697e
5870:The Clinical Journal of Pain
5500:The Clinical Journal of Pain
5295:Hersen P, Sturmey M (2012).
5262:The TMJ Association (2005).
2671:Journal of Clinical Medicine
2183:
1963:muscles of facial expression
1673:Cognitive Behavioral Therapy
1523:Computerised tomography (CT)
1227:Group II: disc displacements
1176:
684:and eating very hard foods.
130:cognitive behavioral therapy
7:
8099:Salivary gland diverticulum
8062:Necrotizing sialometaplasia
7073:Smokeless tobacco keratosis
6985:Basaloid squamous carcinoma
5957:10.1016/j.jebdp.2011.12.001
5796:10.1016/j.jdent.2011.02.006
5238:10.1016/j.bjoms.2013.05.144
4793:10.1016/j.bjorl.2015.06.010
4556:10.2174/1874347101105010001
4494:Australian Family Physician
3417:. World Health Organization
2255:American Dental Association
1566:and metallic heart valves,
1126:The jaw may lock entirely.
810:hormone replacement therapy
351:Definitions and terminology
10:
8525:
8109:Salivary gland hyperplasia
8057:HIV salivary gland disease
7566:Gingival cyst of the adult
7012:Oral florid papillomatosis
6725:
6613:
6308:10.1177/000348949710601003
6228:10.1177/000348949710601002
5741:Journal of Dental Research
5477:10.1016/j.ijom.2023.09.006
5439:10.1016/j.joms.2010.12.014
5383:Dionne RA (January 1997).
5158:10.1016/j.ijom.2010.09.001
5078:10.1016/j.cden.2008.06.001
5038:10.1016/j.cden.2013.04.008
4174:10.1053/j.sult.2007.02.002
2236:
2097:
2093:
1947:Intra-articular injections
1937:, sometimes combined with
1884:have also been described.
1706:
976:
959:temporomandibular ligament
929:
644:
640:
569:Degenerative joint disease
528:Diminished auditory acuity
339:, headache, chronic lower
185:Hyperactivity, spasm, and
118:temporomandibular disorder
116:In this article, the term
18:
8509:Ailments of unknown cause
8499:Musculoskeletal disorders
8454:
8448:
8443:
8356:
8348:Orofacial soft tissues β
8342:
8283:
8266:
8114:Salivary gland hypoplasia
8037:
8024:
7928:
7903:
7842:Bisphosphonate-associated
7736:Idiopathic osteosclerosis
7711:
7689:
7512:
7479:
7207:Dentinogenesis imperfecta
7143:
7117:
6797:
6780:
6733:
6720:
6671:Median rhomboid glossitis
6621:
6608:
6529:
6516:
6435:
6350:
6078:Singh S, Ernst E (2008).
5918:Journal of Orofacial Pain
5710:10.1007/s10484-005-8420-5
5323:Journal of Orofacial Pain
4900:10.1186/s40463-016-0144-4
4576:Journal of Orofacial Pain
4200:Standring S, ed. (2006).
4125:Australian Dental Journal
3933:American Family Physician
3834:10.1007/s13191-011-0041-5
3786:Tyldesley's Oral medicine
3755:10.3200/BMED.33.3.101-118
3157:10.1016/j.pmn.2009.10.003
2972:10.1016/j.jcm.2009.07.006
2350:10.1002/14651858.CD002970
1889:randomized control trials
1874:tricyclic antidepressants
1859:glucosamine hydrochloride
1189:Group I: muscle disorders
967:sphenomandibular ligament
855:Irritable bowel syndrome.
736:statistically significant
687:
546:
406:World Health Organization
60:
55:
46:
38:
33:
8421:Orofacial granulomatosis
8200:Mucoepidermoid carcinoma
8185:Adenoid cystic carcinoma
8119:Salivary gland neoplasms
7910:Temporomandibular joints
7881:Periapical periodontitis
7613:Linear gingival erythema
7381:Regional odontodysplasia
7227:Enamel hypocalcification
6521:
5823:Evidence-Based Dentistry
5753:10.1177/0022034512453324
5562:10.1177/2042533312472115
2169:Chiropractic adjustments
1531:The main indications of
1140:Myofascial pain syndrome
963:stylomandibular ligament
926:Temporomandibular joints
834:Obstructive sleep apnea.
333:irritable bowel syndrome
281:Absent, large, or small
144:after dental pain (i.e.
132:, physical therapy, and
99:temporomandibular joints
8318:Obstructive sleep apnea
8084:Salivary duct stricture
7864:Paget's disease of bone
7361:Pulp canal obliteration
7202:Dentin hypersensitivity
7148:Amelogenesis imperfecta
7000:Squamous cell carcinoma
6980:Adenosquamous carcinoma
6967:Squamous cell papilloma
6944:Melanocytic oral lesion
4838:Medical Science Monitor
4485:Quail G (August 2005).
4243:10.1038/sj.bdj.4801151a
3145:Pain Management Nursing
2253:On March 31, 2020, The
2010:low level laser therapy
1090:
1055:lateral pterygoid plate
940:(hinging joint) and an
932:Temporomandibular joint
653:parafunctional activity
482:Pain and tenderness on
93:and dysfunction of the
56:Temporomandibular joint
8464:Hemifacial hypertrophy
8431:Pyostomatitis vegetans
8104:Salivary gland fistula
8094:Salivary gland atresia
8089:Salivary gland aplasia
7943:Mandibular dislocation
7914:muscles of mastication
7792:Calcifying odontogenic
7421:Vertical root fracture
7416:Cracked tooth syndrome
7391:Shovel-shaped incisors
7286:Wisdom tooth impaction
7168:Early childhood caries
7034:Benign mucous membrane
6995:Spindle cell carcinoma
6904:Intraoral dental sinus
6822:Burning mouth syndrome
6043:10.1186/1746-1340-18-3
5836:10.1038/sj.ebd.6400816
4361:Odell EW, ed. (2010).
4231:British Dental Journal
3362:. IASP. Archived from
2733:Edwab RR, ed. (2003).
2118:therapeutic modalities
2087:
2070:
2016:for their own health.
1774:
1753:
1724:
1716:
1413:oromandibular dystonia
1381:differential diagnosis
1368:
1350:
1073:Mechanisms of symptoms
1011:Left temporalis muscle
979:Muscles of mastication
973:Muscles of mastication
921:Anatomy and physiology
858:Interstitial cystitis.
846:Systemic joint laxity.
703:road traffic accidents
662:central nervous system
660:dysfunction and other
410:
397:
391:2nd edition (ICHD-2),
384:
297:burning mouth syndrome
95:muscles of mastication
8273:Stomatognathic system
8175:Acinic cell carcinoma
7797:Glandular odontogenic
6949:Molluscum contagiosum
5506:(6 Suppl): S198-203.
4988:10.1259/dmfr/25151578
4946:10.1259/dmfr/25523853
4673:10.1259/dmfr/16932758
4278:Head and neck imaging
3261:|...}}
3232:(Retracted, see
3103:|...}}
3074:(Retracted, see
2918:|...}}
2889:(Retracted, see
2614:|...}}
2585:(Retracted, see
2392:|...}}
2363:(Retracted, see
2083:
2066:
2058:restorative dentistry
1854:have also been used.
1766:
1749:
1722:
1714:
1685:Relaxation techniques
1539:diagnostic accuracy.
1362:
1348:
825:Possible associations
413:By cause and symptoms
398:
385:
376:
337:interstitial cystitis
323:pain syndrome, and a
8416:Oral Crohn's disease
8371:Basal cell carcinoma
8010:Condylar hyperplasia
7995:Maxillary hypoplasia
7561:Gingival enlargement
7494:periodontal ligament
7100:Verruciform xanthoma
6832:Condyloma acuminatum
5784:Journal of Dentistry
3575:10.2522/ptj.20140548
3395:on 15 September 2013
2143:Alternative medicine
2062:orthognathic surgery
2012:may help with pain.
1863:chondroitin sulphate
1626:viscosupplementation
1586:, US has inadequate
1514:Panoramic tomography
1409:trigeminal neuralgia
1385:rheumatoid arthritis
1194:Ia. Myofascial pain:
1171:atypical facial pain
850:Rheumatoid arthritis
590:Psychosocial factors
579:rheumatoid arthritis
301:atypical facial pain
8426:Perioral dermatitis
8162:Pleomorphic adenoma
8142:Monomorphic adenoma
8132:Canalicular adenoma
8005:Condylar hypoplasia
7938:Condylar resorption
7782:Lateral periodontal
7741:Mandibular fracture
7640:Periodontal abscess
7237:Turner's hypoplasia
7005:Verrucous carcinoma
6954:Morsicatio buccarum
6934:Lupus erythematosus
6847:Erythema multiforme
6763:Stomatitis nicotina
6222:(10 Pt 1): 805β19.
6157:10.3390/jcm13051365
5072:(4): 875β90, viii.
4850:10.12659/MSM.908810
4515:on 16 November 2006
4466:(Suppl 1): E18-26.
4237:(5): 235β8, 241β5.
3743:Behavioral Medicine
3366:on 19 December 2012
2684:10.3390/jcm13051365
2106:surgical treatments
2047:Occlusal adjustment
1423:Diagnostic criteria
1183:
815:nociceptive neurons
741:Occlusal adjustment
674:morsicatio buccarum
651:Bruxism is an oral
625:, somatization and
305:atypical odontalgia
250:Metabolic disease (
158:
8469:Facial hemiatrophy
8323:Periodic breathing
8254:SjΓΆgren's syndrome
8127:Basal cell adenoma
7891:Torus mandibularis
7869:Periapical abscess
7852:Osteoradionecrosis
7777:Buccal bifurcation
7756:Intraosseous cysts
7645:Periodontal trauma
7549:Pyogenic granuloma
7396:Supernumerary root
7349:Pulp calcification
7337:Premature eruption
7308:Odontogenic tumors
7105:White sponge nevus
7078:Submucous fibrosis
7022:Smoker's melanosis
6909:Irritation fibroma
6748:High-arched palate
6656:Foliate papillitis
6646:Cunnilingus tongue
6631:Black hairy tongue
6561:Congenital lip pit
6436:External resources
6302:(10 Pt 1): 820β2.
5550:JRSM Short Reports
4342:on 13 January 2013
3485:Wright EF (2013).
3449:Okeson JP (2003).
1725:
1717:
1560:ionizing radiation
1389:temporal arteritis
1369:
1351:
1181:
843:Chronic back pain.
840:Chronic neck pain.
819:ΞΌ-opioid receptors
790:female sex hormone
699:general anesthetic
443:Signs and symptoms
156:
8486:
8485:
8482:
8481:
8439:
8438:
8338:
8337:
8262:
8261:
8167:Sebaceous adenoma
8020:
8019:
7899:
7898:
7810:Median mandibular
7805:Nasopalatine duct
7721:Alveolar osteitis
7685:
7684:
7672:Perio-endo lesion
7554:Congenital epulis
7475:
7474:
7232:Enamel hypoplasia
7113:
7112:
7088:RigaβFede disease
6939:Melanocytic nevus
6879:Hairy leukoplakia
6842:Epulis fissuratum
6776:
6775:
6716:
6715:
6666:Geographic tongue
6604:
6603:
6476:
6475:
6198:Costen's syndrome
6089:978-0-393-06661-6
5595:General Dentistry
5306:978-0-470-33546-8
4437:978-0-323-04903-0
4287:978-0-323-05355-6
4215:978-0-443-07168-3
3690:978-1-55009-186-1
3643:Scully C (2008).
3534:978-0-443-07106-5
3496:978-1-118-50269-3
3460:978-0-323-01477-9
3332:978-1-85097-098-9
3323:Applied occlusion
2841:978-0-7216-9003-2
2744:978-0-87814-624-6
2469:978-0-309-67048-7
2224:African Americans
2137:joint replacement
2120:have failed. The
1893:systematic review
1848:methyl salicylate
1745:dental technician
1590:when identifying
1505:Plain radiography
1360:
1343:
1342:
1299:IIIa. Arthralgia:
1163:secondary otalgia
1146:Referred TMD pain
951:synovial membrane
762:monoamine oxidase
627:sleep deprivation
562:lateral pterygoid
556:Disc displacement
469:connective tissue
293:
292:
283:condyloid process
273:(fibrous or bony)
256:chondrocalcinosis
76:
75:
28:Medical condition
8516:
8445:
8444:
8344:
8343:
8268:
8267:
8137:Ductal papilloma
8026:
8025:
7905:
7904:
7802:Non-odontogenic:
7787:Globulomaxillary
7726:Buccal exostosis
7691:
7690:
7635:Peri-implantitis
7481:
7480:
7197:Dentin dysplasia
7119:
7118:
7095:Verruca vulgaris
6990:Mucosal melanoma
6837:Darier's disease
6812:Behçet's disease
6782:
6781:
6738:Bednar's aphthae
6722:
6721:
6610:
6609:
6596:Trumpeter's wart
6518:
6517:
6503:
6496:
6489:
6480:
6479:
6348:
6347:
6342:
6341:
6334:
6328:
6327:
6291:
6280:
6279:
6259:
6248:
6247:
6211:
6205:
6194:
6188:
6187:
6177:
6159:
6135:
6129:
6128:
6100:
6094:
6093:
6075:
6066:
6065:
6055:
6045:
6021:
6015:
6014:
5978:
5969:
5968:
5940:
5934:
5933:
5913:
5902:
5901:
5864:
5849:
5848:
5838:
5817:TΓΌrp JC (2011).
5814:
5808:
5807:
5779:
5773:
5772:
5736:
5730:
5729:
5693:
5687:
5686:
5676:
5644:
5638:
5637:
5617:
5611:
5610:
5590:
5584:
5583:
5573:
5541:
5532:
5531:
5495:
5489:
5488:
5460:
5451:
5450:
5422:
5413:
5412:
5380:
5374:
5373:
5345:
5339:
5338:
5317:
5311:
5310:
5292:
5286:
5285:
5283:
5281:
5275:
5269:. Archived from
5268:
5259:
5250:
5249:
5217:
5211:
5210:
5181:
5170:
5169:
5141:
5128:
5127:
5099:
5090:
5089:
5061:
5050:
5049:
5021:
5010:
5009:
4999:
4967:
4958:
4957:
4929:
4923:
4922:
4912:
4902:
4878:
4872:
4871:
4861:
4829:
4816:
4815:
4805:
4795:
4771:
4756:
4755:
4727:
4721:
4720:
4691:
4685:
4684:
4656:
4645:
4644:
4615:
4602:
4601:
4591:
4567:
4561:
4560:
4558:
4540:
4531:
4525:
4524:
4522:
4520:
4514:
4508:. Archived from
4491:
4482:
4476:
4475:
4457:
4448:
4442:
4441:
4425:
4415:
4394:
4391:
4385:
4384:
4368:
4358:
4352:
4351:
4349:
4347:
4338:. Archived from
4315:
4304:
4303:
4301:
4299:
4290:. Archived from
4269:
4263:
4262:
4226:
4220:
4219:
4207:
4197:
4186:
4185:
4157:
4151:
4150:
4140:
4116:
4110:
4109:
4081:
4075:
4070:
4064:
4063:
4027:
4016:
4015:
3995:
3989:
3988:
3970:
3949:
3948:
3924:
3918:
3917:
3889:
3883:
3882:
3862:
3856:
3855:
3845:
3813:
3800:
3799:
3781:
3775:
3774:
3738:
3717:
3716:
3714:
3712:
3701:
3695:
3694:
3676:
3659:
3658:
3640:
3597:
3596:
3586:
3563:Physical Therapy
3554:
3539:
3538:
3520:
3501:
3500:
3482:
3465:
3464:
3446:
3427:
3426:
3424:
3422:
3411:
3405:
3404:
3402:
3400:
3385:
3376:
3375:
3373:
3371:
3356:
3337:
3336:
3318:
3275:
3274:
3272:
3270:
3262:
3251:Retraction Watch
3230:
3198:
3179:
3178:
3168:
3136:
3117:
3116:
3114:
3112:
3104:
3093:Retraction Watch
3072:
3040:
3021:
3020:
3018:
3016:
3005:
2994:
2993:
2983:
2951:
2932:
2931:
2929:
2927:
2919:
2908:Retraction Watch
2887:
2862:(11): CD008456.
2855:
2846:
2845:
2829:
2819:
2804:
2803:
2777:
2768:
2749:
2748:
2730:
2715:
2714:
2704:
2686:
2662:
2656:
2655:
2653:
2651:
2645:
2637:
2628:
2627:
2625:
2623:
2615:
2604:Retraction Watch
2583:
2551:
2538:
2537:
2509:
2482:
2481:
2456:
2450:
2449:
2447:
2445:
2429:
2406:
2405:
2403:
2401:
2393:
2382:Retraction Watch
2361:
2337:
2328:
2327:
2310:(10): CD004715.
2303:
2276:
2270:
2243:otolaryngologist
1935:local anesthetic
1815:muscle relaxants
1789:(pain killers),
1728:Occlusal splints
1646:over-the-counter
1417:psychogenic pain
1361:
1184:
1180:
1021:
1007:
993:
910:
896:
882:
784:Hormonal factors
729:Occlusal factors
707:tooth extraction
611:vasoconstriction
595:Emotional stress
515:tension headache
507:occipital region
159:
157:Classification:
155:
51:
31:
30:
8524:
8523:
8519:
8518:
8517:
8515:
8514:
8513:
8489:
8488:
8487:
8478:
8450:
8435:
8391:Ludwig's angina
8352:
8334:
8293:Mouth breathing
8279:
8258:
8079:Pneumoparotitis
8052:Frey's syndrome
8033:
8031:Salivary glands
8016:
7924:
7895:
7874:Phoenix abscess
7707:
7703:hard tissues β
7681:
7603:Hypercementosis
7522:Cementoblastoma
7508:
7471:
7185:Dens evaginatus
7139:
7109:
7061:Denture-related
7046:Plasmoacanthoma
6972:Keratoacanthoma
6793:
6791:Lining of mouth
6772:
6768:Torus palatinus
6729:
6712:
6693:Lingual thyroid
6651:Fissured tongue
6641:Crenated tongue
6617:
6600:
6586:Nasolabial cyst
6571:Herpes labialis
6525:
6512:
6507:
6477:
6472:
6471:
6431:
6430:
6359:
6345:
6336:
6335:
6331:
6292:
6283:
6260:
6251:
6212:
6208:
6195:
6191:
6136:
6132:
6101:
6097:
6090:
6076:
6069:
6022:
6018:
5979:
5972:
5941:
5937:
5914:
5905:
5865:
5852:
5815:
5811:
5780:
5776:
5737:
5733:
5694:
5690:
5645:
5641:
5618:
5614:
5591:
5587:
5542:
5535:
5496:
5492:
5461:
5454:
5423:
5416:
5381:
5377:
5346:
5342:
5318:
5314:
5307:
5293:
5289:
5279:
5277:
5276:on 28 July 2011
5273:
5266:
5260:
5253:
5218:
5214:
5182:
5173:
5142:
5131:
5100:
5093:
5062:
5053:
5022:
5013:
4968:
4961:
4930:
4926:
4879:
4875:
4830:
4819:
4772:
4759:
4728:
4724:
4692:
4688:
4657:
4648:
4616:
4605:
4568:
4564:
4538:
4532:
4528:
4518:
4516:
4512:
4489:
4483:
4479:
4455:
4449:
4445:
4438:
4416:
4397:
4392:
4388:
4381:
4359:
4355:
4345:
4343:
4316:
4307:
4297:
4295:
4288:
4270:
4266:
4227:
4223:
4216:
4198:
4189:
4158:
4154:
4117:
4113:
4082:
4078:
4071:
4067:
4028:
4019:
3996:
3992:
3985:
3971:
3952:
3939:(10): 1477β82.
3925:
3921:
3890:
3886:
3863:
3859:
3814:
3803:
3796:
3782:
3778:
3739:
3720:
3710:
3708:
3703:
3702:
3698:
3691:
3677:
3662:
3655:
3641:
3600:
3555:
3542:
3535:
3521:
3504:
3497:
3483:
3468:
3461:
3447:
3430:
3420:
3418:
3413:
3412:
3408:
3398:
3396:
3387:
3386:
3379:
3369:
3367:
3358:
3357:
3340:
3333:
3319:
3278:
3264:
3256:
3254:
3231:
3205:(1): CD002778.
3199:
3182:
3137:
3120:
3106:
3098:
3096:
3073:
3047:(7): CD006541.
3041:
3024:
3014:
3012:
3007:
3006:
2997:
2952:
2935:
2921:
2913:
2911:
2888:
2856:
2849:
2842:
2820:
2807:
2775:
2769:
2752:
2745:
2731:
2718:
2663:
2659:
2649:
2647:
2643:
2639:
2638:
2631:
2617:
2609:
2607:
2584:
2558:(4): CD004973.
2552:
2541:
2510:
2485:
2470:
2458:
2457:
2453:
2443:
2441:
2430:
2409:
2395:
2387:
2385:
2362:
2344:(1): CD002970.
2338:
2331:
2304:
2279:
2271:
2267:
2263:
2239:
2203:
2195:quality of life
2190:natural history
2186:
2166:
2150:
2145:
2102:
2096:
2049:
1988:and subsequent
1971:
1953:Botulinum toxin
1904:drug dependence
1871:anti-muscarinic
1869:. Low-doses of
1819:cyclobenzaprine
1807:anticonvulsants
1791:benzodiazepines
1782:
1709:
1658:
1634:
1611:masseter muscle
1576:
1545:
1525:
1516:
1507:
1482:
1480:Medical imaging
1425:
1353:
1179:
1148:
1116:
1107:
1104:Myofascial Pain
1093:
1080:
1075:
1063:pterygoid fovea
1027:
1026:
1022:
1013:
1012:
1008:
999:
998:
994:
981:
975:
934:
928:
923:
918:
917:
916:
915:
914:
911:
902:
901:
900:
897:
888:
887:
886:
883:
872:
870:Pathophysiology
827:
806:Post-menopausal
798:menstrual cycle
786:
749:
747:Genetic factors
731:
697:whilst under a
690:
649:
643:
592:
571:
558:
549:
536:(occasionally).
530:(hearing loss).
519:myofascial pain
445:
432:
415:
353:
317:rheumatological
309:musculoskeletal
241:and subluxation
154:
134:pain medication
111:quality of life
29:
24:
17:
12:
11:
5:
8522:
8512:
8511:
8506:
8501:
8484:
8483:
8480:
8479:
8477:
8476:
8471:
8466:
8461:
8459:Eagle syndrome
8455:
8452:
8451:
8441:
8440:
8437:
8436:
8434:
8433:
8428:
8423:
8418:
8413:
8408:
8403:
8398:
8393:
8388:
8383:
8381:Cystic hygroma
8378:
8373:
8368:
8363:
8357:
8354:
8353:
8340:
8339:
8336:
8335:
8333:
8332:
8327:
8326:
8325:
8320:
8315:
8310:
8305:
8295:
8290:
8284:
8281:
8280:
8264:
8263:
8260:
8259:
8257:
8256:
8251:
8249:Sialolithiasis
8246:
8241:
8236:
8231:
8226:
8225:
8224:
8219:
8209:
8204:
8203:
8202:
8197:
8192:
8187:
8182:
8180:Adenocarcinoma
8177:
8169:
8164:
8159:
8154:
8149:
8147:Myoepithelioma
8144:
8139:
8134:
8129:
8116:
8111:
8106:
8101:
8096:
8091:
8086:
8081:
8076:
8075:
8074:
8064:
8059:
8054:
8049:
8044:
8038:
8035:
8034:
8022:
8021:
8018:
8017:
8015:
8014:
8013:
8012:
8007:
7997:
7992:
7991:
7990:
7985:
7980:
7975:
7970:
7965:
7960:
7955:
7945:
7940:
7935:
7929:
7926:
7925:
7901:
7900:
7897:
7896:
7894:
7893:
7888:
7883:
7878:
7877:
7876:
7866:
7861:
7856:
7855:
7854:
7849:
7844:
7834:
7829:
7824:
7823:
7822:
7820:Traumatic bone
7817:
7815:Median palatal
7812:
7807:
7799:
7794:
7789:
7784:
7779:
7774:
7769:
7753:
7748:
7743:
7738:
7733:
7728:
7723:
7718:
7712:
7709:
7708:
7687:
7686:
7683:
7682:
7680:
7679:
7674:
7669:
7668:
7667:
7662:
7657:
7647:
7642:
7637:
7632:
7627:
7626:
7625:
7615:
7610:
7608:Hypocementosis
7605:
7600:
7595:
7594:
7593:
7588:
7583:
7573:
7568:
7563:
7558:
7557:
7556:
7551:
7541:
7536:
7531:
7530:
7529:
7519:
7513:
7510:
7509:
7477:
7476:
7473:
7472:
7470:
7469:
7468:
7467:
7462:
7457:
7452:
7442:
7441:
7440:
7430:
7429:
7428:
7423:
7418:
7413:
7403:
7398:
7393:
7388:
7383:
7378:
7373:
7368:
7363:
7358:
7357:
7356:
7346:
7345:
7344:
7342:Neonatal teeth
7334:
7329:
7328:
7327:
7317:
7316:
7315:
7305:
7300:
7295:
7290:
7289:
7288:
7278:
7277:
7276:
7266:
7261:
7256:
7251:
7246:
7241:
7240:
7239:
7229:
7224:
7222:Ectopic enamel
7219:
7214:
7209:
7204:
7199:
7194:
7193:
7192:
7182:
7177:
7172:
7171:
7170:
7160:
7155:
7150:
7144:
7141:
7140:
7115:
7114:
7111:
7110:
7108:
7107:
7102:
7097:
7092:
7091:
7090:
7080:
7075:
7070:
7069:
7068:
7063:
7058:
7048:
7043:
7038:
7037:
7036:
7026:
7025:
7024:
7017:Oral melanosis
7014:
7009:
7008:
7007:
7002:
6997:
6992:
6987:
6982:
6974:
6969:
6956:
6951:
6946:
6941:
6936:
6931:
6926:
6921:
6916:
6911:
6906:
6901:
6896:
6891:
6886:
6881:
6876:
6871:
6866:
6865:
6864:
6854:
6849:
6844:
6839:
6834:
6829:
6824:
6819:
6817:Bohn's nodules
6814:
6809:
6804:
6802:Amalgam tattoo
6798:
6795:
6794:
6778:
6777:
6774:
6773:
6771:
6770:
6765:
6760:
6755:
6750:
6745:
6740:
6734:
6731:
6730:
6718:
6717:
6714:
6713:
6711:
6710:
6705:
6700:
6695:
6690:
6685:
6680:
6679:
6678:
6673:
6668:
6658:
6653:
6648:
6643:
6638:
6633:
6628:
6622:
6619:
6618:
6606:
6605:
6602:
6601:
6599:
6598:
6593:
6588:
6583:
6578:
6573:
6568:
6563:
6558:
6553:
6552:
6551:
6546:
6541:
6530:
6527:
6526:
6514:
6513:
6506:
6505:
6498:
6491:
6483:
6474:
6473:
6470:
6469:
6452:
6440:
6439:
6437:
6433:
6432:
6429:
6428:
6417:
6406:
6391:
6376:
6360:
6355:
6354:
6352:
6351:Classification
6344:
6343:
6329:
6281:
6249:
6206:
6189:
6130:
6095:
6088:
6067:
6016:
5970:
5935:
5903:
5850:
5809:
5774:
5731:
5688:
5659:(6): 594β602.
5639:
5612:
5601:(2): e119-22.
5585:
5533:
5490:
5452:
5433:(7): 1885β91.
5414:
5375:
5340:
5312:
5305:
5287:
5251:
5212:
5171:
5129:
5091:
5051:
5011:
4959:
4924:
4873:
4817:
4757:
4722:
4686:
4646:
4603:
4562:
4526:
4477:
4443:
4436:
4395:
4386:
4379:
4353:
4305:
4286:
4264:
4221:
4214:
4187:
4152:
4111:
4076:
4065:
4017:
3990:
3983:
3950:
3919:
3884:
3857:
3801:
3795:978-0192631473
3794:
3776:
3718:
3696:
3689:
3660:
3653:
3598:
3540:
3533:
3502:
3495:
3466:
3459:
3428:
3406:
3377:
3338:
3331:
3276:
3180:
3118:
3022:
2995:
2933:
2847:
2840:
2805:
2750:
2743:
2716:
2657:
2629:
2539:
2520:(6): 391β410.
2483:
2468:
2451:
2407:
2329:
2277:
2264:
2262:
2259:
2238:
2235:
2202:
2199:
2185:
2182:
2165:
2162:
2149:
2146:
2144:
2141:
2129:arthrocentesis
2098:Main article:
2095:
2092:
2048:
2045:
2026:proprioception
2022:orofacial pain
1970:
1967:
1933:Injections of
1781:
1778:
1758:Dahl appliance
1708:
1705:
1665:, anxiety and
1663:mood disorders
1657:
1654:
1633:
1630:
1622:arthrocentesis
1615:Eagle syndrome
1596:articular disc
1592:osteoarthrosis
1575:
1572:
1544:
1541:
1524:
1521:
1515:
1512:
1506:
1503:
1499:
1498:
1495:
1492:
1489:
1481:
1478:
1477:
1476:
1473:
1472:
1471:
1468:
1465:
1462:
1456:
1453:
1446:
1445:
1442:
1439:
1436:
1424:
1421:
1405:Eagle syndrome
1341:
1340:
1339:
1338:
1335:
1326:
1325:
1322:
1313:
1312:
1309:
1305:
1291:
1290:
1287:
1284:
1281:
1278:
1275:
1266:
1265:
1262:
1259:
1256:
1253:
1244:
1243:
1239:
1224:
1223:
1220:
1217:
1208:
1207:
1204:
1200:
1178:
1175:
1147:
1144:
1115:
1112:
1106:
1101:
1092:
1089:
1079:
1076:
1074:
1071:
1047:
1046:
1043:
1040:
1037:
1029:
1028:
1024:
1023:
1016:
1014:
1010:
1009:
1002:
1000:
996:
995:
988:
977:Main article:
974:
971:
955:synovial fluid
930:Main article:
927:
924:
922:
919:
912:
905:
904:
903:
898:
891:
890:
889:
884:
877:
876:
875:
874:
873:
871:
868:
867:
866:
859:
856:
853:
847:
844:
841:
838:
835:
826:
823:
785:
782:
778:norepinephrine
766:catecholamines
748:
745:
730:
727:
689:
686:
645:Main article:
642:
639:
591:
588:
575:osteoarthritis
570:
567:
557:
554:
548:
545:
544:
543:
540:
537:
531:
525:
522:
496:
495:
492:
488:
444:
441:
437:secondary care
431:
428:
414:
411:
364:United Kingdom
352:
349:
291:
290:
289:
288:
285:
279:
274:
268:
259:
248:
245:
242:
236:
233:
229:
228:
227:
226:
225:
224:
212:
211:
202:
199:
196:
191:Inflammation (
189:
182:
181:
180:
179:
178:
177:
176:
175:
153:
152:Classification
150:
142:orofacial pain
74:
73:
64:
58:
57:
53:
52:
44:
43:
40:
36:
35:
27:
15:
9:
6:
4:
3:
2:
8521:
8510:
8507:
8505:
8502:
8500:
8497:
8496:
8494:
8475:
8472:
8470:
8467:
8465:
8462:
8460:
8457:
8456:
8453:
8446:
8442:
8432:
8429:
8427:
8424:
8422:
8419:
8417:
8414:
8412:
8409:
8407:
8404:
8402:
8399:
8397:
8394:
8392:
8389:
8387:
8384:
8382:
8379:
8377:
8374:
8372:
8369:
8367:
8364:
8362:
8361:Actinomycosis
8359:
8358:
8355:
8351:
8345:
8341:
8331:
8328:
8324:
8321:
8319:
8316:
8314:
8311:
8309:
8306:
8304:
8301:
8300:
8299:
8296:
8294:
8291:
8289:
8286:
8285:
8282:
8278:
8274:
8269:
8265:
8255:
8252:
8250:
8247:
8245:
8242:
8240:
8239:Sialodochitis
8237:
8235:
8232:
8230:
8227:
8223:
8220:
8218:
8215:
8214:
8213:
8210:
8208:
8205:
8201:
8198:
8196:
8193:
8191:
8188:
8186:
8183:
8181:
8178:
8176:
8173:
8170:
8168:
8165:
8163:
8160:
8158:
8155:
8153:
8150:
8148:
8145:
8143:
8140:
8138:
8135:
8133:
8130:
8128:
8125:
8122:
8121:
8120:
8117:
8115:
8112:
8110:
8107:
8105:
8102:
8100:
8097:
8095:
8092:
8090:
8087:
8085:
8082:
8080:
8077:
8073:
8070:
8069:
8068:
8065:
8063:
8060:
8058:
8055:
8053:
8050:
8048:
8045:
8043:
8040:
8039:
8036:
8032:
8027:
8023:
8011:
8008:
8006:
8003:
8002:
8001:
7998:
7996:
7993:
7989:
7986:
7984:
7981:
7979:
7976:
7974:
7971:
7969:
7966:
7964:
7961:
7959:
7956:
7954:
7951:
7950:
7949:
7946:
7944:
7941:
7939:
7936:
7934:
7931:
7930:
7927:
7923:
7919:
7918:malocclusions
7915:
7911:
7906:
7902:
7892:
7889:
7887:
7886:Stafne defect
7884:
7882:
7879:
7875:
7872:
7871:
7870:
7867:
7865:
7862:
7860:
7857:
7853:
7850:
7848:
7845:
7843:
7840:
7839:
7838:
7837:Osteonecrosis
7835:
7833:
7832:Osteomyelitis
7830:
7828:
7825:
7821:
7818:
7816:
7813:
7811:
7808:
7806:
7803:
7800:
7798:
7795:
7793:
7790:
7788:
7785:
7783:
7780:
7778:
7775:
7773:
7770:
7768:
7765:
7763:
7759:
7758:
7757:
7754:
7752:
7749:
7747:
7744:
7742:
7739:
7737:
7734:
7732:
7729:
7727:
7724:
7722:
7719:
7717:
7714:
7713:
7710:
7706:
7705:Bones of jaws
7702:
7698:
7692:
7688:
7678:
7675:
7673:
7670:
7666:
7663:
7661:
7658:
7656:
7653:
7652:
7651:
7650:Periodontitis
7648:
7646:
7643:
7641:
7638:
7636:
7633:
7631:
7630:Pericoronitis
7628:
7624:
7621:
7620:
7619:
7616:
7614:
7611:
7609:
7606:
7604:
7601:
7599:
7596:
7592:
7589:
7587:
7586:Granulomatous
7584:
7582:
7579:
7578:
7577:
7574:
7572:
7569:
7567:
7564:
7562:
7559:
7555:
7552:
7550:
7547:
7546:
7545:
7542:
7540:
7539:Eruption cyst
7537:
7535:
7532:
7528:
7525:
7524:
7523:
7520:
7518:
7515:
7514:
7511:
7507:
7503:
7499:
7495:
7491:
7487:
7482:
7478:
7466:
7463:
7461:
7458:
7456:
7453:
7451:
7448:
7447:
7446:
7443:
7439:
7436:
7435:
7434:
7431:
7427:
7424:
7422:
7419:
7417:
7414:
7412:
7409:
7408:
7407:
7404:
7402:
7399:
7397:
7394:
7392:
7389:
7387:
7384:
7382:
7379:
7377:
7374:
7372:
7369:
7367:
7366:Pulp necrosis
7364:
7362:
7359:
7355:
7352:
7351:
7350:
7347:
7343:
7340:
7339:
7338:
7335:
7333:
7330:
7326:
7325:Dens in dente
7323:
7322:
7321:
7318:
7314:
7311:
7310:
7309:
7306:
7304:
7301:
7299:
7296:
7294:
7291:
7287:
7284:
7283:
7282:
7279:
7275:
7272:
7271:
7270:
7267:
7265:
7262:
7260:
7257:
7255:
7252:
7250:
7247:
7245:
7242:
7238:
7235:
7234:
7233:
7230:
7228:
7225:
7223:
7220:
7218:
7217:Discoloration
7215:
7213:
7210:
7208:
7205:
7203:
7200:
7198:
7195:
7191:
7188:
7187:
7186:
7183:
7181:
7178:
7176:
7173:
7169:
7166:
7165:
7164:
7161:
7159:
7156:
7154:
7151:
7149:
7146:
7145:
7142:
7137:
7133:
7129:
7125:
7120:
7116:
7106:
7103:
7101:
7098:
7096:
7093:
7089:
7086:
7085:
7084:
7081:
7079:
7076:
7074:
7071:
7067:
7064:
7062:
7059:
7057:
7054:
7053:
7052:
7049:
7047:
7044:
7042:
7039:
7035:
7032:
7031:
7030:
7027:
7023:
7020:
7019:
7018:
7015:
7013:
7010:
7006:
7003:
7001:
6998:
6996:
6993:
6991:
6988:
6986:
6983:
6981:
6978:
6975:
6973:
6970:
6968:
6965:
6962:
6961:
6960:
6957:
6955:
6952:
6950:
6947:
6945:
6942:
6940:
6937:
6935:
6932:
6930:
6927:
6925:
6924:Lichen planus
6922:
6920:
6917:
6915:
6912:
6910:
6907:
6905:
6902:
6900:
6899:Herpes zoster
6897:
6895:
6892:
6890:
6887:
6885:
6882:
6880:
6877:
6875:
6874:Fordyce spots
6872:
6870:
6867:
6863:
6860:
6859:
6858:
6855:
6853:
6852:Erythroplakia
6850:
6848:
6845:
6843:
6840:
6838:
6835:
6833:
6830:
6828:
6825:
6823:
6820:
6818:
6815:
6813:
6810:
6808:
6805:
6803:
6800:
6799:
6796:
6792:
6788:
6783:
6779:
6769:
6766:
6764:
6761:
6759:
6756:
6754:
6751:
6749:
6746:
6744:
6741:
6739:
6736:
6735:
6732:
6728:
6723:
6719:
6709:
6706:
6704:
6701:
6699:
6696:
6694:
6691:
6689:
6686:
6684:
6681:
6677:
6674:
6672:
6669:
6667:
6664:
6663:
6662:
6659:
6657:
6654:
6652:
6649:
6647:
6644:
6642:
6639:
6637:
6636:Caviar tongue
6634:
6632:
6629:
6627:
6626:Ankyloglossia
6624:
6623:
6620:
6616:
6611:
6607:
6597:
6594:
6592:
6591:Sun poisoning
6589:
6587:
6584:
6582:
6579:
6577:
6574:
6572:
6569:
6567:
6564:
6562:
6559:
6557:
6554:
6550:
6547:
6545:
6542:
6540:
6537:
6536:
6535:
6532:
6531:
6528:
6524:
6519:
6515:
6511:
6504:
6499:
6497:
6492:
6490:
6485:
6484:
6481:
6468:
6465:
6462:
6458:
6457:
6453:
6451:
6447:
6446:
6442:
6441:
6438:
6434:
6427:
6423:
6422:
6418:
6416:
6412:
6411:
6407:
6405:
6401:
6400:
6396:
6392:
6390:
6386:
6385:
6381:
6377:
6375:
6371:
6370:
6366:
6362:
6361:
6358:
6353:
6349:
6339:
6333:
6325:
6321:
6317:
6313:
6309:
6305:
6301:
6297:
6290:
6288:
6286:
6277:
6273:
6269:
6265:
6258:
6256:
6254:
6245:
6241:
6237:
6233:
6229:
6225:
6221:
6217:
6210:
6204:
6203:Who Named It?
6200:
6199:
6193:
6185:
6181:
6176:
6171:
6167:
6163:
6158:
6153:
6149:
6145:
6141:
6134:
6126:
6122:
6118:
6114:
6111:(6): 430β51.
6110:
6106:
6099:
6091:
6085:
6081:
6074:
6072:
6063:
6059:
6054:
6049:
6044:
6039:
6035:
6031:
6027:
6020:
6012:
6008:
6004:
6000:
5996:
5992:
5988:
5984:
5977:
5975:
5966:
5962:
5958:
5954:
5950:
5946:
5939:
5931:
5927:
5924:(2): 152β62.
5923:
5919:
5912:
5910:
5908:
5899:
5895:
5891:
5887:
5883:
5879:
5876:(6): 541β50.
5875:
5871:
5863:
5861:
5859:
5857:
5855:
5846:
5842:
5837:
5832:
5828:
5824:
5820:
5813:
5805:
5801:
5797:
5793:
5790:(5): 341β50.
5789:
5785:
5778:
5770:
5766:
5762:
5758:
5754:
5750:
5747:(8): 745β52.
5746:
5742:
5735:
5727:
5723:
5719:
5715:
5711:
5707:
5704:(4): 333β45.
5703:
5699:
5692:
5684:
5680:
5675:
5670:
5666:
5662:
5658:
5654:
5650:
5643:
5635:
5631:
5627:
5623:
5616:
5608:
5604:
5600:
5596:
5589:
5581:
5577:
5572:
5567:
5563:
5559:
5555:
5551:
5547:
5540:
5538:
5529:
5525:
5521:
5517:
5513:
5509:
5505:
5501:
5494:
5486:
5482:
5478:
5474:
5470:
5466:
5459:
5457:
5448:
5444:
5440:
5436:
5432:
5428:
5421:
5419:
5410:
5406:
5402:
5398:
5395:(1): 134β42.
5394:
5390:
5386:
5379:
5371:
5367:
5363:
5359:
5356:(3): 477β98.
5355:
5351:
5344:
5336:
5332:
5329:(3): 237β54.
5328:
5324:
5316:
5308:
5302:
5298:
5291:
5272:
5265:
5258:
5256:
5247:
5243:
5239:
5235:
5231:
5227:
5223:
5216:
5208:
5204:
5200:
5196:
5192:
5188:
5180:
5178:
5176:
5167:
5163:
5159:
5155:
5151:
5147:
5140:
5138:
5136:
5134:
5125:
5121:
5117:
5113:
5109:
5105:
5098:
5096:
5087:
5083:
5079:
5075:
5071:
5067:
5060:
5058:
5056:
5047:
5043:
5039:
5035:
5032:(3): 405β18.
5031:
5027:
5020:
5018:
5016:
5007:
5003:
4998:
4993:
4989:
4985:
4981:
4977:
4973:
4966:
4964:
4955:
4951:
4947:
4943:
4939:
4935:
4928:
4920:
4916:
4911:
4906:
4901:
4896:
4892:
4888:
4884:
4877:
4869:
4865:
4860:
4855:
4851:
4847:
4843:
4839:
4835:
4828:
4826:
4824:
4822:
4813:
4809:
4804:
4799:
4794:
4789:
4786:(3): 341β52.
4785:
4781:
4777:
4770:
4768:
4766:
4764:
4762:
4753:
4749:
4745:
4741:
4738:(10): 771β8.
4737:
4733:
4726:
4718:
4714:
4710:
4706:
4703:(2): e52-63.
4702:
4698:
4690:
4682:
4678:
4674:
4670:
4666:
4662:
4655:
4653:
4651:
4642:
4638:
4634:
4630:
4627:(4): 521β36.
4626:
4622:
4614:
4612:
4610:
4608:
4599:
4595:
4590:
4585:
4581:
4577:
4573:
4566:
4557:
4552:
4548:
4544:
4537:
4530:
4511:
4507:
4503:
4499:
4495:
4488:
4481:
4473:
4469:
4465:
4461:
4454:
4447:
4439:
4433:
4429:
4424:
4423:
4414:
4412:
4410:
4408:
4406:
4404:
4402:
4400:
4390:
4382:
4380:9780443067846
4376:
4372:
4367:
4366:
4357:
4341:
4337:
4333:
4330:(2): 102β12.
4329:
4325:
4321:
4314:
4312:
4310:
4294:on 2 May 2014
4293:
4289:
4283:
4279:
4275:
4268:
4260:
4256:
4252:
4248:
4244:
4240:
4236:
4232:
4225:
4217:
4211:
4206:
4205:
4196:
4194:
4192:
4183:
4179:
4175:
4171:
4168:(3): 170β83.
4167:
4163:
4156:
4148:
4144:
4139:
4134:
4131:(3): 265β71.
4130:
4126:
4122:
4115:
4107:
4103:
4099:
4095:
4092:(3): 157β63.
4091:
4087:
4080:
4074:
4069:
4061:
4057:
4053:
4049:
4045:
4041:
4038:(4): 287β92.
4037:
4033:
4026:
4024:
4022:
4013:
4009:
4005:
4001:
4000:Stomatologija
3994:
3986:
3984:9780199204830
3980:
3976:
3969:
3967:
3965:
3963:
3961:
3959:
3957:
3955:
3946:
3942:
3938:
3934:
3930:
3923:
3915:
3911:
3907:
3903:
3900:(6): e26-50.
3899:
3895:
3888:
3880:
3876:
3873:(4): 124β38.
3872:
3868:
3861:
3853:
3849:
3844:
3839:
3835:
3831:
3827:
3823:
3819:
3812:
3810:
3808:
3806:
3797:
3791:
3787:
3780:
3772:
3768:
3764:
3760:
3756:
3752:
3749:(3): 101β18.
3748:
3744:
3737:
3735:
3733:
3731:
3729:
3727:
3725:
3723:
3706:
3700:
3692:
3686:
3682:
3675:
3673:
3671:
3669:
3667:
3665:
3656:
3654:9780443068188
3650:
3646:
3639:
3637:
3635:
3633:
3631:
3629:
3627:
3625:
3623:
3621:
3619:
3617:
3615:
3613:
3611:
3609:
3607:
3605:
3603:
3594:
3590:
3585:
3580:
3576:
3572:
3568:
3564:
3560:
3553:
3551:
3549:
3547:
3545:
3536:
3530:
3526:
3519:
3517:
3515:
3513:
3511:
3509:
3507:
3498:
3492:
3488:
3481:
3479:
3477:
3475:
3473:
3471:
3462:
3456:
3452:
3445:
3443:
3441:
3439:
3437:
3435:
3433:
3416:
3410:
3394:
3390:
3384:
3382:
3365:
3361:
3355:
3353:
3351:
3349:
3347:
3345:
3343:
3334:
3328:
3324:
3317:
3315:
3313:
3311:
3309:
3307:
3305:
3303:
3301:
3299:
3297:
3295:
3293:
3291:
3289:
3287:
3285:
3283:
3281:
3268:
3260:
3253:
3252:
3247:
3243:
3239:
3235:
3228:
3224:
3220:
3216:
3212:
3208:
3204:
3197:
3195:
3193:
3191:
3189:
3187:
3185:
3176:
3172:
3167:
3162:
3158:
3154:
3150:
3146:
3142:
3135:
3133:
3131:
3129:
3127:
3125:
3123:
3110:
3102:
3095:
3094:
3089:
3085:
3081:
3077:
3070:
3066:
3062:
3058:
3054:
3050:
3046:
3039:
3037:
3035:
3033:
3031:
3029:
3027:
3010:
3004:
3002:
3000:
2991:
2987:
2982:
2977:
2973:
2969:
2966:(4): 171β86.
2965:
2961:
2957:
2950:
2948:
2946:
2944:
2942:
2940:
2938:
2925:
2917:
2910:
2909:
2904:
2900:
2896:
2892:
2885:
2881:
2877:
2873:
2869:
2865:
2861:
2854:
2852:
2843:
2837:
2833:
2828:
2827:
2818:
2816:
2814:
2812:
2810:
2801:
2797:
2793:
2789:
2786:(4): 453β62.
2785:
2781:
2774:
2767:
2765:
2763:
2761:
2759:
2757:
2755:
2746:
2740:
2736:
2729:
2727:
2725:
2723:
2721:
2712:
2708:
2703:
2698:
2694:
2690:
2685:
2680:
2676:
2672:
2668:
2661:
2642:
2636:
2634:
2621:
2613:
2606:
2605:
2600:
2596:
2592:
2588:
2581:
2577:
2573:
2569:
2565:
2561:
2557:
2550:
2548:
2546:
2544:
2535:
2531:
2527:
2523:
2519:
2515:
2508:
2506:
2504:
2502:
2500:
2498:
2496:
2494:
2492:
2490:
2488:
2479:
2475:
2471:
2465:
2461:
2455:
2439:
2435:
2428:
2426:
2424:
2422:
2420:
2418:
2416:
2414:
2412:
2399:
2391:
2384:
2383:
2378:
2374:
2370:
2366:
2359:
2355:
2351:
2347:
2343:
2336:
2334:
2325:
2321:
2317:
2313:
2309:
2302:
2300:
2298:
2296:
2294:
2292:
2290:
2288:
2286:
2284:
2282:
2274:
2273:TMJ Disorders
2269:
2265:
2258:
2256:
2251:
2248:
2244:
2234:
2231:
2227:
2225:
2221:
2217:
2211:
2207:
2198:
2196:
2191:
2181:
2178:
2174:
2170:
2161:
2159:
2154:
2140:
2138:
2134:
2130:
2125:
2123:
2119:
2115:
2111:
2107:
2101:
2091:
2086:
2082:
2078:
2076:
2069:
2065:
2063:
2059:
2055:
2044:
2042:
2037:
2033:
2029:
2027:
2023:
2017:
2013:
2011:
2007:
2003:
1999:
1994:
1991:
1987:
1982:
1979:
1975:
1974:Physiotherapy
1969:Physiotherapy
1966:
1964:
1959:
1958:acetylcholine
1954:
1950:
1948:
1944:
1940:
1936:
1931:
1929:
1925:
1921:
1917:
1913:
1909:
1905:
1901:
1896:
1894:
1890:
1887:Despite many
1885:
1883:
1882:nortriptyline
1879:
1878:amitriptyline
1875:
1872:
1868:
1864:
1860:
1855:
1853:
1849:
1846:
1842:
1840:
1836:
1832:
1828:
1824:
1820:
1816:
1812:
1808:
1804:
1800:
1796:
1792:
1788:
1777:
1773:
1771:
1765:
1761:
1759:
1752:
1748:
1746:
1742:
1736:
1733:
1729:
1721:
1713:
1704:
1702:
1698:
1694:
1690:
1686:
1682:
1680:
1676:
1674:
1670:
1668:
1664:
1653:
1651:
1647:
1643:
1639:
1629:
1627:
1623:
1618:
1616:
1612:
1607:
1603:
1601:
1597:
1593:
1589:
1585:
1581:
1571:
1569:
1568:ferromagnetic
1565:
1561:
1556:
1552:
1549:
1540:
1536:
1534:
1529:
1528:examination.
1520:
1511:
1502:
1496:
1493:
1490:
1487:
1486:
1485:
1474:
1469:
1466:
1463:
1460:
1459:
1457:
1454:
1451:
1450:
1449:
1443:
1440:
1437:
1434:
1433:
1432:
1429:
1420:
1418:
1414:
1410:
1406:
1402:
1401:osteomyelitis
1399:, mandibular
1398:
1394:
1390:
1386:
1382:
1378:
1374:
1366:
1365:real-time MRI
1347:
1336:
1333:
1332:
1331:
1330:
1323:
1320:
1319:
1318:
1317:
1310:
1306:
1303:
1302:
1301:
1300:
1296:
1295:
1288:
1285:
1282:
1279:
1276:
1273:
1272:
1271:
1270:
1263:
1260:
1257:
1254:
1251:
1250:
1249:
1248:
1240:
1236:
1235:
1234:
1233:
1229:
1228:
1221:
1218:
1215:
1214:
1213:
1212:
1205:
1201:
1198:
1197:
1196:
1195:
1191:
1190:
1186:
1185:
1174:
1172:
1169:, as well as
1168:
1164:
1160:
1156:
1151:
1143:
1141:
1135:
1133:
1127:
1124:
1121:
1111:
1105:
1100:
1097:
1088:
1086:
1070:
1068:
1067:sphenoid bone
1064:
1060:
1056:
1052:
1044:
1041:
1038:
1035:
1034:
1033:
1020:
1015:
1006:
1001:
992:
987:
986:
985:
980:
970:
968:
964:
960:
956:
952:
947:
946:temporal bone
943:
939:
933:
909:
895:
881:
864:
860:
857:
854:
851:
848:
845:
842:
839:
836:
833:
832:
831:
822:
820:
816:
811:
807:
803:
799:
794:
791:
781:
779:
775:
771:
767:
763:
759:
755:
744:
742:
737:
726:
724:
719:
715:
710:
708:
704:
700:
696:
685:
683:
679:
675:
670:
666:
663:
659:
654:
648:
638:
635:
632:
628:
624:
619:
616:
612:
608:
607:limbic system
604:
600:
596:
587:
584:
580:
576:
566:
563:
553:
541:
538:
535:
532:
529:
526:
523:
520:
516:
512:
508:
504:
503:
502:
499:
493:
489:
485:
481:
480:
479:
476:
474:
470:
466:
462:
458:
454:
450:
440:
438:
427:
424:
420:
409:
407:
403:
396:
394:
390:
383:
381:
375:
372:
369:
365:
360:
358:
348:
346:
342:
338:
334:
330:
326:
322:
318:
314:
313:neuromuscular
310:
306:
302:
298:
286:
284:
280:
278:
275:
272:
269:
267:
263:
260:
257:
253:
249:
246:
243:
240:
237:
234:
231:
230:
223:
222:
218:
217:
216:
215:
214:
213:
210:
206:
203:
200:
197:
194:
190:
188:
184:
183:
174:
173:
169:
168:
167:
166:
165:
164:
163:
162:
161:
160:
149:
147:
143:
137:
135:
131:
125:
123:
119:
114:
112:
108:
104:
100:
96:
92:
88:
84:
80:
72:
71:Oral medicine
68:
65:
63:
59:
54:
50:
45:
41:
37:
32:
26:
22:
8349:
8276:
8212:Sialadenitis
8171:
8123:
7999:
7988:Scissor bite
7983:Retrognathia
7968:Overeruption
7948:Malocclusion
7921:
7801:
7760:
7751:Micrognathia
7704:
7695:Periapical,
7581:Desquamative
7505:
7486:Periodontium
7460:Acid erosion
7401:Taurodontism
7332:Open contact
7244:Enamel pearl
7212:Dilaceration
7175:Concrescence
6976:
6963:
6790:
6743:Cleft palate
6703:Microglossia
6698:Macroglossia
6683:Glossoptosis
6581:Microcheilia
6576:Macrocheilia
6454:
6443:
6419:
6408:
6393:
6378:
6363:
6332:
6299:
6295:
6270:(1): 163β7.
6267:
6263:
6219:
6215:
6209:
6196:
6192:
6147:
6143:
6133:
6108:
6104:
6098:
6079:
6033:
6029:
6019:
5986:
5982:
5948:
5944:
5938:
5921:
5917:
5873:
5869:
5826:
5822:
5812:
5787:
5783:
5777:
5744:
5740:
5734:
5701:
5697:
5691:
5656:
5652:
5642:
5628:(5): 681β5.
5625:
5621:
5615:
5598:
5594:
5588:
5553:
5549:
5503:
5499:
5493:
5471:(1): 45β56.
5468:
5464:
5430:
5426:
5392:
5388:
5378:
5353:
5349:
5343:
5326:
5322:
5315:
5296:
5290:
5278:. Retrieved
5271:the original
5232:(7): 667β8.
5229:
5225:
5215:
5193:(1): 112β7.
5190:
5186:
5149:
5145:
5110:(5): 633β9.
5107:
5103:
5069:
5065:
5029:
5025:
4982:(5): 270β6.
4979:
4975:
4940:(4): 192β7.
4937:
4933:
4927:
4890:
4886:
4876:
4841:
4837:
4783:
4779:
4735:
4731:
4725:
4700:
4696:
4689:
4667:(2): 63β71.
4664:
4660:
4624:
4620:
4582:(1): 79β88.
4579:
4575:
4565:
4546:
4542:
4529:
4517:. Retrieved
4510:the original
4500:(8): 641β5.
4497:
4493:
4480:
4463:
4459:
4446:
4421:
4389:
4364:
4356:
4344:. Retrieved
4340:the original
4327:
4323:
4296:. Retrieved
4292:the original
4277:
4267:
4234:
4230:
4224:
4203:
4165:
4161:
4155:
4128:
4124:
4114:
4089:
4085:
4079:
4068:
4035:
4031:
4006:(1): 26β31.
4003:
3999:
3993:
3974:
3936:
3932:
3922:
3897:
3893:
3887:
3870:
3866:
3860:
3828:(3): 141β8.
3825:
3821:
3785:
3779:
3746:
3742:
3709:. Retrieved
3699:
3680:
3644:
3566:
3562:
3524:
3486:
3450:
3419:. Retrieved
3409:
3397:. Retrieved
3393:the original
3368:. Retrieved
3364:the original
3322:
3265:{{
3257:{{
3250:
3248:,
3202:
3151:(1): 15β24.
3148:
3144:
3107:{{
3099:{{
3092:
3090:,
3044:
3013:. Retrieved
2963:
2959:
2922:{{
2914:{{
2907:
2905:,
2859:
2825:
2783:
2779:
2734:
2674:
2670:
2660:
2648:. Retrieved
2618:{{
2610:{{
2603:
2601:,
2555:
2517:
2513:
2459:
2454:
2442:. Retrieved
2437:
2396:{{
2388:{{
2381:
2379:,
2341:
2307:
2268:
2252:
2247:malocclusion
2240:
2232:
2228:
2212:
2208:
2204:
2201:Epidemiology
2187:
2173:case reports
2167:
2164:Chiropractic
2151:
2126:
2103:
2088:
2084:
2079:
2071:
2067:
2054:orthodontics
2050:
2038:
2034:
2030:
2018:
2014:
1995:
1983:
1972:
1951:
1932:
1897:
1886:
1856:
1850:and topical
1843:
1783:
1775:
1767:
1762:
1754:
1750:
1737:
1726:
1683:
1677:
1671:
1659:
1650:prescription
1635:
1619:
1608:
1604:
1577:
1557:
1553:
1546:
1537:
1530:
1526:
1517:
1508:
1500:
1483:
1447:
1430:
1426:
1393:otitis media
1373:auscultation
1370:
1328:
1327:
1315:
1314:
1298:
1297:
1293:
1292:
1268:
1267:
1246:
1245:
1231:
1230:
1226:
1225:
1210:
1209:
1193:
1192:
1188:
1187:
1152:
1149:
1136:
1128:
1125:
1117:
1108:
1103:
1098:
1094:
1081:
1078:Joint noises
1048:
1030:
982:
935:
863:scuba diving
828:
787:
750:
732:
711:
691:
671:
667:
658:dopaminergic
650:
636:
631:risk factors
620:
593:
572:
559:
550:
500:
497:
477:
446:
439:(hospital).
433:
416:
399:
386:
377:
373:
361:
354:
343:and chronic
329:fibromyalgia
294:
221:Arthrogenic:
220:
219:
171:
170:
138:
126:
121:
117:
115:
86:
82:
78:
77:
25:
8406:Microstomia
8396:Macrostomia
8386:Gnathophyma
8303:Catathrenia
8298:Sleep apnea
8229:Sialectasis
7772:Dentigerous
7762:Odontogenic
7591:Plasma cell
7527:Gigantiform
7303:Microdontia
7293:Macrodontia
7264:Hyperdontia
6959:Oral cancer
6919:Leukoplakia
6827:Candidiasis
6787:Oral mucosa
6708:Rhabdomyoma
6688:Hypoglossia
6549:Plasma cell
6445:MedlinePlus
6150:(5): 1365.
5152:(1): 45β9.
4844:: 812β817.
3569:(1): 9β25.
2677:(5): 1365.
2216:nulliparous
2177:case series
2153:Acupuncture
2148:Acupuncture
2133:arthroscopy
2041:biofeedback
1924:hydrocodone
1867:propranolol
1701:sympathetic
1588:specificity
1584:sensitivity
1377:stethoscope
774:epinephrine
682:nail biting
430:By duration
325:psychogenic
239:Dislocation
209:hypertrophy
39:Other names
8493:Categories
8366:Angioedema
8172:Malignant:
8152:Oncocytoma
7978:Prognathia
7767:periapical
7746:Microgenia
7697:mandibular
7655:Aggressive
7576:Gingivitis
7517:Cementicle
7455:Abfraction
7445:Tooth wear
7438:Edentulism
7433:Tooth loss
7386:Resorption
7371:Pulp polyp
7354:Pulp stone
7298:Meth mouth
7269:Hypodontia
7259:Gemination
7190:Talon cusp
7083:Ulceration
7051:Stomatitis
7029:Pemphigoid
6977:Malignant:
6929:Linea alba
6914:Leukoedema
6894:Herpangina
6862:Giant-cell
6421:DiseasesDB
5951:(1): 2β4.
5280:2 December
2261:References
2220:caucasians
2006:ultrasound
2002:endorphins
1831:diclofenac
1811:gabapentin
1795:clonazepam
1787:analgesics
1780:Medication
1697:meditation
1632:Management
1580:ultrasound
1574:Ultrasound
1564:pacemakers
1308:excursion;
1051:originates
942:arthrodial
758:phenotypes
718:idiopathic
695:intubation
678:linea alba
623:depression
583:autoimmune
539:Dizziness.
423:idiopathic
321:functional
262:Capsulitis
247:Infections
8234:Sialocele
8217:Parotitis
7958:Open bite
7953:Crossbite
7731:Cherubism
7701:maxillary
7534:Cementoma
7465:Attrition
7281:Impaction
7249:Fluorosis
7158:Anodontia
7153:Ankylosis
7041:Pemphigus
6661:Glossitis
6556:Cleft lip
6534:Cheilitis
6467:emerg/569
6464:radio/679
6461:neuro/366
6456:eMedicine
6166:2077-0383
5989:: 243β9.
5829:(3): 89.
5556:(2): 10.
4893:(1): 30.
3267:retracted
3259:retracted
3109:retracted
3101:retracted
2924:retracted
2916:retracted
2693:2077-0383
2620:retracted
2612:retracted
2398:retracted
2390:retracted
2184:Prognosis
2108:based on
1990:hyperemia
1943:cytokines
1928:methadone
1916:oxycodone
1852:capsaicin
1839:celecoxib
1827:piroxicam
1642:neurology
1638:dentistry
1397:parotitis
1177:Diagnosis
1085:ear canal
938:ginglymus
837:Headache.
802:ovulation
723:incidence
599:autonomic
491:movement.
484:palpation
471:, or the
461:ligaments
345:neck pain
341:back pain
287:Neoplasia
271:Ankylosis
266:synovitis
244:Arthritis
172:Muscular:
146:toothache
62:Specialty
8244:Sialosis
8195:Lymphoma
8067:Mucocele
7963:Overbite
7716:Agnathia
7677:Teething
7502:alveolus
7498:cementum
7450:Abrasion
7426:Occlusal
7411:Avulsion
7376:Pulpitis
7320:Odontoma
7066:Herpetic
7056:Aphthous
6566:Eclabium
6324:57196481
6244:30664556
6184:38592227
6175:10931584
6125:20438615
6062:20184717
6011:35775630
6003:16523145
5965:22326146
5930:20401353
5898:12402484
5890:20551730
5845:21979775
5804:21354460
5769:46145202
5761:22744995
5718:16385422
5683:23329239
5634:23356206
5607:22414516
5580:23476731
5528:37480726
5520:12569969
5485:37802670
5447:21419546
5335:20664825
5246:23769713
5207:21543241
5166:20961737
5124:16677922
5086:18805233
5046:23809300
5006:20587650
4954:17536085
4919:27164975
4868:29420457
4812:26832630
4752:20492436
4717:18547834
4681:18239033
4641:16997121
4598:20213033
4506:16113700
4472:15800464
4336:21357496
4259:29993073
4251:11575759
4182:17571700
4147:21884141
4106:15341139
4060:20752594
4052:15089931
4012:19423968
3945:18052012
3914:20451831
3852:21886404
3771:20540193
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