29:
1931:
841:, and intestines of infected hosts, and shedding can occur for months or years. Some adenoviruses (e.g., serotypes 1, 2, 5, and 6) have been shown to be endemic in parts of the world where they have been studied, and infection is usually acquired during childhood. Other types cause sporadic infection and occasional outbreaks; for example, epidemic
908:. Strict attention to good infection-control practices is effective for stopping transmission in hospitals of adenovirus-associated disease, such as epidemic keratoconjunctivitis. Maintaining adequate levels of chlorination is necessary for preventing swimming pool-associated outbreaks of adenovirus conjunctivitis.
545:
disease is rare in people who are otherwise healthy. Adenovirus infection accounts for up to 10% of respiratory infections in children. Most cases are mild and by the age of 10-years, most children have had at least one adenovirus infection. 75% of conjunctivitis cases are due to adenovirus infection. In 2016, the
988:
Adenovirus infections occur sporadically throughout the year, and outbreaks can occur particularly in winter and spring. Epidemics may spread more quickly in closed populations such as in hospitals, nurseries, long-term care facilities, boarding schools, orphanages and swimming pools. Severe disease
845:
is associated with adenovirus serotypes 8, 19, and 37. Epidemics of febrile disease with conjunctivitis are associated with waterborne transmission of some adenovirus types, often centering on inadequately chlorinated swimming pools and small lakes. ARD is most often associated with adenovirus types
912:
to protect against types 4 and 7 adenoviruses has been used in some military personnel. Rates of adenovirus disease fell among military recruits following the introduction a live oral vaccine against types 4 and 7. Stocks of the vaccine ran out in 1999 and rates of disease increased until 2011 when
850:
cause gastroenteritis, usually in children. For some adenovirus serotypes, the clinical spectrum of disease associated with infection varies depending on the site of infection; for example, infection with adenovirus 7 acquired by inhalation is associated with severe lower respiratory tract disease,
558:
Symptoms are variable, ranging from mild symptoms to severe illness. They depend on the type of adenovirus, where it enters into the body, and on the age and well-being of the person. Recognised patterns of clinical features include respiratory, eye, gastrointestinal, genitourinary and central
544:
Adenovirus infections affect all ages. They occur sporadically throughout the year, and outbreaks can occur particularly in winter and spring, when they may spread more quickly in closed populations such as in hospitals, nurseries, long-term care facilities, schools, and swimming pools. Severe
851:
whereas oral transmission of the virus typically causes no or mild disease. Outbreaks of adenovirus-associated respiratory disease have been more common in the late winter, spring, and early summer; however, adenovirus infections can occur throughout the year.
739:
and abdominal pain, with or without respiratory or general symptoms. Children under the age of one-year appear particularly vulnerable. However, it usually resolves within three-days. It appears similar to diarrhoea diseases caused by other infections.
651:. It presents with a hyperinflated chest, expiratory wheeze and low oxygen. Severe pneumonia is most common in very young children age three to 18 months and presents with sudden illness, ongoing cough, high fever, shortness of breath and a
989:
is rare in people who are usually healthy. Around 10% of respiratory infections in children are caused by adenoviruses. Most are mild and by the age of 10-years, most children have had at least one adenovirus infection.
549:
estimated that globally, around 75 million episodes of diarrhea among children under the age of five-years, were attributable to adenovirus infection. The first adenoviral strains were isolated in 1953 by Rowe et al.
2250:
715:. A sore throat and nasal congestion may or may not be present. This tends to occur in epidemics, affecting predominantly adults. In very young children, it may be associated with high fever, sore throat,
1935:
1015:
Research in adenovirus infection has generally been limited relative to other respiratory disease viruses. The impact of type-40/41 adenovirus diarrhoea is possibly underestimated.
1012:
estimated that globally, around 75 million episodes of diarrhea among children under the age of five-years, were attributable to adenovirus infection, with a mortality of near 12%.
1042:
in San
Antonio. In 2018, outbreaks occurred in an adult nursing home in New Jersey, and a college campus in Maryland. In 2020, as a result of infection control measures during the
870:
on blood or respiratory secretions may detect adenovirus DNA. Adenovirus can be isolated by growing in cell cultures in a laboratory. Other conditions that appear similar include
929:. Medicines to ease pain and reduce fever can be bought over the counter. For adenoviral conjunctivitis, a cold compress and lubricants may provide some relief of discomfort.
866:
Diagnosis is by signs and symptoms, and a laboratory test is not usually required. In some circumstances such as severe disease, when a diagnosis needs to be confirmed, a
1000:, with type 41 being more common than type 40. Some large studies have revealed type 40/41 adenovirus as one of the second most common causes of diarrhea in children in
683:
may present as a pinkish-red eye. Six to nine days following exposure to adenovirus, one or both eyes, typically in children, may be affected in association with fever,
2881:
1035:
resulted in detecting previously unrecognized adenoviruses types 40 and 41, subsequently found to be important in causing gastrointestinal illness in children.
639:, runny nose and abdominal pain. There may be a harsh barking cough. It is frequently associated with a fever and a sore throat. Up to one in five infants with
996:. 75% of conjunctivitis cases are due to adenovirus infection. Under two-year olds are particularly susceptible to adenovirus gastroenteritis by types 40 and
2304:
1221:
2895:
521:. Adenovirus gastroenteritis appears similar to diarrhoeal diseases caused by other infections. Infection by adenovirus may be prevented by
2076:
3314:
1940:
886:. Since adenovirus can be excreted for prolonged periods, the presence of virus does not necessarily mean it is associated with disease.
2561:
2392:
1946:
541:. Most adenovirus infections get better without any treatment. Medicines to ease pain and reduce fever can be bought over the counter.
2432:
699:. Typically one eye is affected after an incubation period of up to a week. The eye becomes itchy, painful, burning and reddish and
703:
may be felt by the ear nearest the affected eye. The symptoms may last around 10 days to three weeks. It may be is associated with
624:
252:
1403:
2297:
2167:
2099:"Nonpharmaceutical interventions against the COVID-19 pandemic significantly decreased the spread of enterovirus in children"
2056:
1884:
1686:
1147:
533:
to protect against types 4 and 7 adenoviruses has been used successfully in some military personnel. Management is generally
2525:
2582:
479:
178:
559:
nervous system. There is also a widespread type that occurs in immunocompromised people. Typical symptoms are of a mild
2901:
2427:
2384:
1848:
55:
2887:
2816:
2290:
854:
Several adenoviruses, including Ad5, Ad9, Ad31, Ad36, Ad37, and SMAM1, have at least some evidence of causation of
1001:
696:
414:
125:
2486:
2472:
1172:
1009:
546:
2847:
1038:
The illness made headlines in Texas in
September 2007, when a so-called "boot camp flu" sickened hundreds at
2924:
1721:"Pediatric acute gastroenteritis associated with adenovirus 40/41 in low-income and middle-income countries"
501:
Diagnosis is by signs and symptoms, and a laboratory test is not usually required. In some circumstances, a
3309:
2691:
2685:
2596:
2590:
2480:
505:
on blood or respiratory secretions may detect adenovirus DNA. Other conditions that appear similar include
1466:
3054:
2980:
2974:
2647:
1055:
883:
518:
350:
289:
454:
occurs mainly when an infected person is in close contact with another person. This may occur by either
808:
in men, when it may present with burning on passing urine associated with red eyes and feeling unwell.
1615:"Adenovirus: Epidemiology, Global Spread of Novel Serotypes, and Advances in Treatment and Prevention"
3111:
2718:
2185:"Infectious canine hepatitis, not only in the textbooks : a brief review and three case reports"
1028:
867:
805:
502:
265:
2820:
2732:
2637:
2467:
2440:
2412:
2345:
2265:
1327:"Human adenovirus infections in pediatric population - An update on clinico-pathologic correlation"
961:
644:
647:
is uncommon, but can occur if adenovirus causes pneumonia with prolonged fever, and can result in
2616:
1539:
1039:
830:
441:
and abdominal pain, with or without respiratory symptoms. However, some people have no symptoms.
166:
156:
2282:
2158:. In Drobatz, Kenneth J.; Hopper, Kate; Rozanski, Elizabeth A.; Silverstein, Deborah C. (eds.).
3010:
2988:
2867:
2863:
2859:
2855:
2810:
2748:
2642:
2603:
2406:
1950:
1135:
777:
272:
2155:
1872:
1836:
1674:
3304:
2995:
2576:
2446:
2417:
459:
451:
28:
1077:
3259:
2726:
2555:
957:
953:
934:
842:
648:
455:
2071:
8:
2677:
2398:
1432:
1032:
997:
847:
834:
829:
characteristics of the adenoviruses vary by type, all are transmitted by direct contact,
761:
487:
463:
370:
192:
41:
945:
After recovery from adenovirus infection, the virus can be carried for weeks or months.
837:. Some types are capable of establishing persistent asymptomatic infections in tonsils,
3071:
3066:
2780:
2536:
2214:
2131:
2098:
2000:
1809:
1774:
1745:
1720:
1647:
1614:
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1372:
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909:
895:
530:
418:
48:
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2935:
2852:
2757:
2461:
2339:
2218:
2206:
2163:
2136:
2118:
2052:
1992:
1909:
1880:
1844:
1814:
1796:
1750:
1682:
1652:
1634:
1498:
1486:
1395:
1376:
1364:
1346:
1143:
1043:
905:
801:
592:
526:
402:
303:
259:
36:
2018:
691:(pharyngoconjunctival fever (PCF)). The onset is usually sudden, and there is often
611:. However, some people have no symptoms. Generally, a day or two after developing a
3219:
2929:
2609:
2541:
2422:
2353:
2196:
2126:
2110:
2004:
1984:
1804:
1786:
1740:
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1354:
1338:
922:
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572:
534:
495:
471:
358:
186:
59:
3183:
3143:
3048:
2968:
2957:
2828:
2792:
2712:
2498:
2359:
2270:
2080:
1971:
Voss, Jameson D.; Atkinson, Richard L.; Dhurandhar, Nikhil V. (1 November 2015).
1736:
977:
926:
728:
700:
688:
616:
538:
430:
398:
138:
110:
1901:
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406:
394:
202:
150:
116:
102:
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522:
514:
475:
342:
299:
285:
216:
182:
1568:
619:
can be felt in the neck. Illness is more likely to be severe in people with
3235:
3085:
2763:
2624:
2140:
1996:
1913:
1818:
1754:
1656:
1630:
1368:
826:
818:
781:
716:
660:
588:
446:
426:
346:
235:
206:
1773:
Labib, Bisant A; Minhas, Bhawanjot K; Chigbu, DeGaulle I (17 March 2020).
858:
in animals, adipogenesis in cells, and/or association with human obesity.
748:
Uncommonly the bladder may be affected, presenting with a sudden onset of
3275:
3224:
3212:
3207:
3200:
3188:
3162:
3132:
3034:
2873:
2785:
2768:
2703:
2364:
1791:
1775:"Management of Adenoviral Keratoconjunctivitis: Challenges and Solutions"
993:
973:
965:
773:
712:
708:
684:
612:
560:
483:
422:
410:
354:
243:
198:
133:
129:
120:
106:
3125:
2909:
2666:
753:
668:
664:
652:
2242:
2114:
904:, avoiding touching own eyes, mouth and nose before washing hands and
764:, which may occur in people with weakened immune systems such as with
525:, avoiding touching own eyes, mouth and nose with unwashed hands, and
3170:
3151:
3118:
3106:
3100:
3079:
3025:
2953:
2839:
2801:
2570:
2549:
2455:
2333:
2325:
2313:
1988:
1005:
949:
875:
871:
797:
757:
732:
564:
510:
506:
491:
438:
374:
319:
281:
277:
222:
212:
174:
142:
75:
1972:
3268:
2915:
2657:
2513:
969:
793:
789:
785:
769:
736:
692:
608:
576:
434:
390:
362:
146:
98:
63:
2046:
3021:
2312:
1078:"Adenovirus Clinical Overview for Healthcare Professionals | CDC"
1046:, rates of adenovirus diarrhoea declined significantly in China.
1024:
855:
838:
784:. Other signs and symptoms depend on other complications such as
749:
604:
596:
386:
382:
248:
94:
86:
635:
Preschool children with adenovirus colds tend to present with a
2630:
2254:
937:. Most adenovirus infections get better without any treatment.
656:
600:
467:
90:
71:
466:
containing the virus. Less commonly, the virus may spread via
3281:
3040:
2672:
1875:. In Feather, Adam; Randall, David; Waterhouse, Mona (eds.).
1058:
is a classical infectious disease seen in unvaccinated dogs.
752:
and increased frequency of passing urine, followed by seeing
580:
568:
378:
366:
82:
67:
2182:
1835:
Haveman, Lianne M.; Bierings, Marc; Wolf, Tom F.W. (2004).
1173:"Adenovirus Infection and Outbreaks: What You Need to Know"
765:
2183:
De Jonge, Bert; Van
Brantegem, Leen; Chiers, Koen (2020).
1841:
The
Microbe-Host Interface in Respiratory Tract Infections
846:
4 and 7 in the United States. Enteric adenoviruses 40 and
2507:
2097:
Zhang, Junfeng; Cao, JiaJia; Ye, Qing (26 April 2022).
1964:
816:
Adenovirus infection in humans are generally caused by
444:
Adenovirus infection in humans are generally caused by
1970:
1900:
Young, Ashley; Toncar, Alicia; Wray, Anton A. (2022).
643:
will have adenovirus infection, which can be severe.
2232:
2042:
2040:
1719:
Lee, B; Damon, CF; Platts-Mills, JA (October 2020).
1718:
992:
Adenoviruses are the most common viruses causing an
425:
and discharge. Very young children may just have an
2085:
New Form of Virus Has Caused 10 Deaths in 18 Months
1834:
1613:Lynch, Joseph P.; Kajon, Adriana E. (August 2016).
1465:Arnold, Amber; MacMahon, Eithne (1 December 2021).
1619:Seminars in Respiratory and Critical Care Medicine
332:Common, all ages, typically children under 5-years
2037:
1772:
1681:. Singapore: World Scientific. pp. 153–183.
1427:
1425:
1423:
1421:
960:. Severe adenovirus pneumonia also may result in
772:. Adenovirus infection may result in symptoms of
159:: Burning and increase frequency of passing urine
3296:
1839:. In Kimpen, Jan L. L.; Ramilo, Octavio (eds.).
1540:"Adenovirus: preventing and treating Adenovirus"
1027:in 1953 by Rowe et al. Later, during studies on
1023:The first adenoviral strains were isolated from
1899:
964:, a subacute inflammatory process in which the
2154:Gonzales, Anthony L.; King, Lesley G. (2019).
1870:
1464:
1418:
1138:. In Goldman, Lee; Schafer, Andrew I. (eds.).
1129:
1127:
1125:
1123:
1121:
1119:
1054:Dogs can be affected by adenovirus infection.
2298:
2047:Kliegman, Robert; Richard M Kliegman (2006).
1830:
1828:
1390:
1388:
1386:
1222:"Adenovirus Infections - Infectious Diseases"
1117:
1115:
1113:
1111:
1109:
1107:
1105:
1103:
1101:
1099:
1072:
1070:
2153:
2011:
1866:
1864:
1862:
1860:
1768:
1766:
1764:
1679:Human Adenoviruses: From Villains To Vectors
1672:
1668:
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1608:
1606:
1604:
1602:
1600:
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1282:
1280:
1278:
1276:
1274:
1272:
1270:
1268:
1266:
1264:
1262:
900:Infection by adenovirus may be prevented by
2160:Textbook of Small Animal Emergency Medicine
2147:
1534:
1532:
1530:
1528:
1260:
1258:
1256:
1254:
1252:
1250:
1248:
1246:
1244:
1242:
2562:Progressive multifocal leukoencephalopathy
2305:
2291:
2096:
1947:Centers for Disease Control and Prevention
1871:White, Veronica; Ruperelia, Prina (2020).
1825:
1714:
1712:
1710:
1708:
1706:
1704:
1702:
1700:
1698:
1612:
1526:
1524:
1522:
1520:
1518:
1516:
1514:
1512:
1510:
1508:
1383:
1096:
1067:
470:. Other respiratory complications include
132:, watery eyes, discharge, swelling of the
27:
2433:Extranodal NK/T-cell lymphoma, nasal type
2200:
2162:. Hoboken: Wiley Blackwell. p. 234.
2130:
1925:
1923:
1893:
1857:
1808:
1790:
1761:
1744:
1673:Flint, S. Jane; Nemerow, Glen R. (2017).
1663:
1646:
1587:
1451:
1358:
1215:
1213:
1211:
1209:
1207:
1205:
1203:
1201:
1167:
1165:
1163:
1161:
1159:
1142:(26th ed.). Elsevier. p. 2163.
722:
353:. Typical symptoms range from those of a
2090:
1879:(10th ed.). Elsevier. p. 947.
1239:
1186:. American Thoracic Society: 13–14. 2019
948:Adenovirus can cause severe necrotizing
591:. Onset is usually two to fourteen days
429:. Adenovirus infection can present as a
401:. Onset is usually two to fourteen days
1695:
1505:
625:hematopoietic stem cell transplantation
623:, particularly children who have had a
587:. Infants may also have symptoms of an
253:hematopoietic stem cell transplantation
3297:
2176:
1942:Respiratory and Enteric Viruses Branch
1920:
1725:Current Opinion in Infectious Diseases
1563:
1561:
1219:
1198:
1156:
811:
695:. Adenovirus infection can also cause
409:may occur on its own, combined with a
2286:
1324:
553:
306:, avoid touching eyes, nose and mouth
2051:. St. Louis, Mo: Elsevier Saunders.
1133:
630:
2583:Subacute sclerosing panencephalitis
2189:Vlaams Diergeneeskundig Tijdschrift
1877:Kumar and Clark's Clinical Medicine
1843:. Norfolk: CRC Press. p. 271.
1558:
1325:Shieh, Wun-Ju (10 September 2021).
952:in which all or part of a lung has
760:may occur in adenovirus associated
480:acute respiratory distress syndrome
179:acute respiratory distress syndrome
13:
3315:Viral respiratory tract infections
2019:"Clinical Diagnosis of Adenovirus"
1406:from the original on 18 April 2020
956:radiographically, which is called
627:. Sometimes there is a skin rash.
14:
3326:
2902:Severe acute respiratory syndrome
2428:Follicular dendritic cell sarcoma
2228:
1973:"Role of adenoviruses in obesity"
933:eye drops may be required if the
800:, generally in people who have a
727:Adenovirus infection can cause a
377:. Other general symptoms include
324:Usually recover without treatment
2888:Middle East respiratory syndrome
1934: This article incorporates
1929:
1220:Tesini, Brenda L. (April 2022).
1049:
804:. Adenovirus is a rare cause of
128:: red painful eye, poor vision,
2065:
2049:Nelson essentials of pediatrics
1226:MSD Manual Professional Edition
1002:low and middle income countries
983:
913:the vaccine was re-introduced.
906:avoiding being near sick people
743:
697:adenoviral keratoconjunctivitis
527:avoiding being near sick people
415:adenoviral keratoconjunctivitis
413:and fever, or as a more severe
2487:Adult T-cell leukemia/lymphoma
2473:Splenic marginal zone lymphoma
1010:Global Burden of Disease Study
972:, resulting in a reduction in
547:Global Burden of Disease Study
1:
1061:
889:
2692:Tropical spastic paraparesis
2597:Lymphocytic choriomeningitis
1737:10.1097/QCO.0000000000000663
1337:(1): S2319–4170(21)00109–8.
940:
916:
861:
115:Pharyngoconjunctival fever:
7:
3055:Cytomegalovirus esophagitis
2975:Human parainfluenza viruses
2648:Ramsay Hunt syndrome type 2
2103:Journal of Medical Virology
2087:published November 16, 2007
1483:10.1016/j.mpmed.2021.09.013
884:respiratory syncytial virus
719:, diarrhoea, and vomiting.
595:to the virus. There may be
519:respiratory syncytial virus
351:respiratory tract infection
290:respiratory syncytial virus
10:
3331:
1433:"Adenovirus: transmission"
1136:"341. Adenovirus diseases"
1018:
893:
349:, commonly resulting in a
314:Symptomatic and supportive
3258:
3234:
3142:
3065:
3020:
3009:
2838:
2800:
2779:
2747:
2719:Cytomegalovirus retinitis
2702:
2656:
2535:
2524:
2497:
2324:
2236:
1908:. StatPearls Publishing.
1180:Am J Respir Crit Care Med
1134:Ison, Michael G. (2019).
910:A live adenovirus vaccine
731:when it may present with
328:
318:
310:
295:
271:
258:
242:
230:
165:
47:
35:
26:
21:
2821:Infectious mononucleosis
2638:Chandipura vesiculovirus
2468:Hepatocellular carcinoma
2413:Nasopharyngeal carcinoma
2346:Hepatocellular carcinoma
2202:10.21825/vdt.v89i5.16956
1873:"28.Respiratory disease"
1343:10.1016/j.bj.2021.08.009
1004:; the most common being
962:bronchiolitis obliterans
750:burning on passing urine
645:Bronchiolitis obliterans
2617:Encephalitis lethargica
2318:viral systemic diseases
1467:"Adenovirus infections"
1040:Lackland Air Force Base
921:Treatment is generally
835:waterborne transmission
831:fecal-oral transmission
674:
655:. There are frequently
621:weakened immune systems
157:Urinary tract infection
2989:Human orthopneumovirus
2643:Herpesviral meningitis
2604:Arbovirus encephalitis
2156:"37. Bronchopneumonia"
1936:public domain material
1779:Clinical Ophthalmology
1631:10.1055/s-0036-1584923
1396:"Adenovirus: symptoms"
1140:Goldman-Cecil Medicine
954:increased translucency
802:weakened immune system
778:dilated cardiomyopathy
723:Gastrointestinal tract
653:fast rate of breathing
273:Differential diagnosis
2447:Merkel-cell carcinoma
822:types B, C, E and F.
468:contaminated surfaces
460:airborne transmission
450:types B, C, E and F.
405:to the virus. A mild
78:sometimes no symptoms
3092:Adenovirus infection
2556:Human polyomavirus 2
2385:Oropharyngeal cancer
1792:10.2147/OPTH.S207976
958:Swyer-James Syndrome
843:keratoconjunctivitis
756:a day or two later.
711:and swelling of the
649:difficulty breathing
615:with large tonsils,
423:intolerance to light
371:difficulty breathing
339:Adenovirus infection
264:Signs and symptoms,
130:intolerance to light
126:Keratoconjunctivitis
22:Adenovirus infection
3310:Atypical pneumonias
2678:Post-polio syndrome
2314:Infectious diseases
1056:Severe liver damage
1033:electron microscopy
1031:, the wider use of
1029:rotavirus diarrhoea
833:, and occasionally
812:Cause and mechanism
762:meningoencephalitis
496:weak immune systems
488:meningoencephalitis
399:swollen neck glands
193:meningoencephalitis
42:Infectious diseases
2811:Epstein–Barr virus
2781:Respiratory system
2418:Burkitt's lymphoma
2079:2015-06-11 at the
2025:. 29 November 2021
1546:. 29 November 2021
1439:. 29 November 2021
1331:Biomedical Journal
1084:. 29 November 2021
935:cornea is involved
896:Adenovirus vaccine
754:blood in the urine
563:or resembling the
554:Signs and symptoms
3292:
3291:
3254:
3253:
3005:
3004:
2936:Influenza virus A
2853:Human coronavirus
2743:
2742:
2733:Herpes of the eye
2280:
2279:
2169:978-1-119-02893-2
2115:10.1002/jmv.27806
2058:978-0-8089-2325-1
1886:978-0-7020-7870-5
1688:978-981-310-979-7
1675:"8. Pathogenesis"
1402:. 16 March 2021.
1149:978-0-323-55087-1
1044:COVID-19 pandemic
631:Respiratory tract
336:
335:
304:social distancing
260:Diagnostic method
56:Upper respiratory
16:Medical condition
3322:
3018:
3017:
3013:digestive system
2930:Orthomyxoviridae
2896:SARS coronavirus
2882:MERS coronavirus
2798:
2797:
2610:Orthomyxoviridae
2533:
2532:
2499:Immune disorders
2423:Hodgkin lymphoma
2399:Kaposi's sarcoma
2307:
2300:
2293:
2284:
2283:
2234:
2233:
2223:
2222:
2204:
2180:
2174:
2173:
2151:
2145:
2144:
2134:
2109:(8): 3581–3588.
2094:
2088:
2069:
2063:
2062:
2044:
2035:
2034:
2032:
2030:
2015:
2009:
2008:
1989:10.1002/rmv.1852
1968:
1962:
1961:
1959:
1958:
1949:. Archived from
1933:
1932:
1927:
1918:
1917:
1897:
1891:
1890:
1868:
1855:
1854:
1837:"12. Adenovirus"
1832:
1823:
1822:
1812:
1794:
1770:
1759:
1758:
1748:
1716:
1693:
1692:
1670:
1661:
1660:
1650:
1610:
1585:
1584:
1582:
1580:
1565:
1556:
1555:
1553:
1551:
1536:
1503:
1502:
1462:
1449:
1448:
1446:
1444:
1429:
1416:
1415:
1413:
1411:
1392:
1381:
1380:
1362:
1322:
1237:
1236:
1234:
1232:
1217:
1196:
1195:
1193:
1191:
1177:
1169:
1154:
1153:
1131:
1094:
1093:
1091:
1089:
1074:
968:are replaced by
637:nasal congestion
573:nasal congestion
472:acute bronchitis
456:fecal–oral route
359:nasal congestion
341:is a contagious
187:acute bronchitis
60:nasal congestion
31:
19:
18:
3330:
3329:
3325:
3324:
3323:
3321:
3320:
3319:
3295:
3294:
3293:
3288:
3250:
3230:
3138:
3112:Gastroenteritis
3070:
3067:Gastroenteritis
3061:
3049:Cytomegalovirus
3012:
3001:
2969:Paramyxoviridae
2958:Avian influenza
2834:
2829:Cytomegalovirus
2793:viral pneumonia
2791:
2788:nasopharyngitis
2787:
2784:
2775:
2739:
2713:Cytomegalovirus
2698:
2652:
2540:
2527:
2520:
2493:
2360:Cervical cancer
2320:
2311:
2281:
2276:
2275:
2245:
2231:
2226:
2181:
2177:
2170:
2152:
2148:
2095:
2091:
2081:Wayback Machine
2070:
2066:
2059:
2045:
2038:
2028:
2026:
2017:
2016:
2012:
1977:Rev. Med. Virol
1969:
1965:
1956:
1954:
1953:on July 3, 2007
1939:
1930:
1928:
1921:
1898:
1894:
1887:
1869:
1858:
1851:
1833:
1826:
1771:
1762:
1717:
1696:
1689:
1671:
1664:
1611:
1588:
1578:
1576:
1575:. 16 March 2021
1567:
1566:
1559:
1549:
1547:
1538:
1537:
1506:
1477:(12): 790–793.
1463:
1452:
1442:
1440:
1431:
1430:
1419:
1409:
1407:
1394:
1393:
1384:
1323:
1240:
1230:
1228:
1218:
1199:
1189:
1187:
1175:
1171:
1170:
1157:
1150:
1132:
1097:
1087:
1085:
1076:
1075:
1068:
1064:
1052:
1021:
1008:. In 2016, the
994:inflamed throat
986:
978:lung compliance
943:
919:
898:
892:
864:
814:
746:
729:gastroenteritis
725:
701:lymphadenopathy
689:lymphadenopathy
677:
633:
556:
494:in people with
482:. It may cause
431:gastroenteritis
417:with a painful
139:Gastroenteritis
111:lymphadenopathy
17:
12:
11:
5:
3328:
3318:
3317:
3312:
3307:
3290:
3289:
3287:
3286:
3285:
3284:
3272:
3264:
3262:
3256:
3255:
3252:
3251:
3249:
3248:
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3238:
3232:
3231:
3229:
3228:
3216:
3204:
3192:
3180:
3173:
3167:
3166:
3154:
3148:
3146:
3140:
3139:
3137:
3136:
3129:
3122:
3115:
3103:
3097:
3096:
3095:
3094:
3082:
3076:
3074:
3063:
3062:
3060:
3059:
3058:
3057:
3045:
3044:
3043:
3030:
3028:
3015:
3007:
3006:
3003:
3002:
3000:
2999:
2992:
2985:
2984:
2983:
2963:
2962:
2961:
2960:
2921:
2920:
2919:
2918:
2906:
2905:
2904:
2892:
2891:
2890:
2878:
2877:
2876:
2844:
2842:
2836:
2835:
2833:
2832:
2825:
2824:
2823:
2806:
2804:
2795:
2777:
2776:
2774:
2773:
2772:
2771:
2766:
2753:
2751:
2749:Cardiovascular
2745:
2744:
2741:
2740:
2738:
2737:
2736:
2735:
2723:
2722:
2721:
2708:
2706:
2700:
2699:
2697:
2696:
2695:
2694:
2682:
2681:
2680:
2675:
2662:
2660:
2654:
2653:
2651:
2650:
2645:
2640:
2635:
2634:
2633:
2621:
2620:
2619:
2606:
2601:
2600:
2599:
2587:
2586:
2585:
2573:
2567:
2566:
2565:
2564:
2552:
2546:
2544:
2530:
2528:nervous system
2522:
2521:
2519:
2518:
2517:
2516:
2503:
2501:
2495:
2494:
2492:
2491:
2490:
2489:
2477:
2476:
2475:
2470:
2458:
2452:
2451:
2450:
2449:
2437:
2436:
2435:
2430:
2425:
2420:
2415:
2403:
2402:
2401:
2389:
2388:
2387:
2382:
2380:Vaginal cancer
2377:
2372:
2367:
2362:
2350:
2349:
2348:
2336:
2330:
2328:
2322:
2321:
2310:
2309:
2302:
2295:
2287:
2278:
2277:
2274:
2273:
2262:
2246:
2241:
2240:
2238:
2237:Classification
2230:
2229:External links
2227:
2225:
2224:
2195:(5): 284–291.
2175:
2168:
2146:
2089:
2073:New York Times
2064:
2057:
2036:
2010:
1983:(6): 379–387.
1963:
1919:
1892:
1885:
1856:
1849:
1824:
1760:
1731:(5): 398–403.
1694:
1687:
1662:
1625:(4): 586–602.
1586:
1557:
1504:
1450:
1417:
1382:
1238:
1197:
1155:
1148:
1095:
1065:
1063:
1060:
1051:
1048:
1020:
1017:
985:
982:
942:
939:
918:
915:
891:
888:
872:whooping cough
863:
860:
813:
810:
745:
742:
724:
721:
705:blurred vision
676:
673:
632:
629:
593:after exposure
585:pinky-red eyes
555:
552:
531:A live vaccine
507:whooping cough
464:small droplets
403:after exposure
395:abdominal pain
334:
333:
330:
326:
325:
322:
316:
315:
312:
308:
307:
297:
293:
292:
278:Whooping cough
275:
269:
268:
262:
256:
255:
246:
240:
239:
232:
228:
227:
226:
225:
219:
209:
203:cardiomyopathy
195:
189:
169:
163:
162:
161:
160:
154:
136:
123:
117:pinky-red eyes
113:
79:
76:fast breathing
51:
45:
44:
39:
33:
32:
24:
23:
15:
9:
6:
4:
3:
2:
3327:
3316:
3313:
3311:
3308:
3306:
3303:
3302:
3300:
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3280:
3279:
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3277:
3273:
3271:
3270:
3266:
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3263:
3261:
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3239:
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3233:
3226:
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3221:
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3210:
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3205:
3202:
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3197:
3193:
3190:
3186:
3185:
3181:
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3159:
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3147:
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3141:
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3130:
3128:
3127:
3123:
3121:
3120:
3116:
3113:
3109:
3108:
3104:
3102:
3099:
3098:
3093:
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3089:
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3087:
3083:
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3078:
3077:
3075:
3073:
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3053:
3052:
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3039:
3038:
3037:
3036:
3032:
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3029:
3027:
3023:
3019:
3016:
3014:
3008:
2998:
2997:
2993:
2991:
2990:
2986:
2982:
2981:Parainfluenza
2979:
2978:
2977:
2976:
2971:
2970:
2965:
2964:
2959:
2955:
2952:
2951:
2950:
2949:
2945:
2941:
2937:
2932:
2931:
2926:
2923:
2922:
2917:
2914:
2913:
2912:
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2907:
2903:
2900:
2899:
2898:
2897:
2893:
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2886:
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2883:
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2872:
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2869:
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2854:
2849:
2846:
2845:
2843:
2841:
2837:
2831:
2830:
2826:
2822:
2818:
2817:EBV infection
2815:
2814:
2813:
2812:
2808:
2807:
2805:
2803:
2799:
2796:
2794:
2789:
2782:
2778:
2770:
2767:
2765:
2762:
2761:
2760:
2759:
2755:
2754:
2752:
2750:
2746:
2734:
2731:
2730:
2729:
2728:
2724:
2720:
2717:
2716:
2715:
2714:
2710:
2709:
2707:
2705:
2701:
2693:
2690:
2689:
2688:
2687:
2683:
2679:
2676:
2674:
2673:Poliomyelitis
2671:
2670:
2669:
2668:
2664:
2663:
2661:
2659:
2655:
2649:
2646:
2644:
2641:
2639:
2636:
2632:
2629:
2628:
2627:
2626:
2622:
2618:
2615:
2614:
2612:
2611:
2607:
2605:
2602:
2598:
2595:
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2593:
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2376:
2375:Vulvar cancer
2373:
2371:
2370:Penile cancer
2368:
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2363:
2361:
2358:
2357:
2356:
2355:
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2112:
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2100:
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2082:
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2075:
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2068:
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2054:
2050:
2043:
2041:
2024:
2020:
2014:
2006:
2002:
1998:
1994:
1990:
1986:
1982:
1978:
1974:
1967:
1952:
1948:
1944:
1943:
1937:
1926:
1924:
1915:
1911:
1907:
1903:
1896:
1888:
1882:
1878:
1874:
1867:
1865:
1863:
1861:
1852:
1850:0-8493-3646-5
1846:
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1838:
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1829:
1820:
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1798:
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1106:
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1102:
1100:
1083:
1079:
1073:
1071:
1066:
1059:
1057:
1050:Other animals
1047:
1045:
1041:
1036:
1034:
1030:
1026:
1016:
1013:
1011:
1007:
1003:
999:
995:
990:
981:
979:
975:
971:
967:
966:small airways
963:
959:
955:
951:
946:
938:
936:
932:
928:
924:
914:
911:
907:
903:
902:washing hands
897:
887:
885:
881:
880:parainfluenza
877:
873:
869:
859:
857:
852:
849:
844:
840:
836:
832:
828:
827:epidemiologic
823:
821:
820:
809:
807:
803:
799:
795:
791:
787:
783:
779:
775:
771:
767:
763:
759:
755:
751:
741:
738:
734:
730:
720:
718:
714:
710:
706:
702:
698:
694:
690:
686:
682:
681:eye infection
672:
670:
666:
662:
658:
654:
650:
646:
642:
641:bronchiolitis
638:
628:
626:
622:
618:
614:
610:
606:
602:
598:
594:
590:
589:ear infection
586:
582:
578:
574:
570:
566:
562:
551:
548:
542:
540:
536:
532:
528:
524:
523:washing hands
520:
516:
515:parainfluenza
512:
508:
504:
499:
497:
493:
489:
485:
481:
477:
476:bronchiolitis
473:
469:
465:
461:
457:
453:
449:
448:
442:
440:
436:
432:
428:
424:
420:
416:
412:
408:
407:eye infection
404:
400:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
356:
352:
348:
344:
343:viral disease
340:
331:
327:
323:
321:
317:
313:
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2027:. Retrieved
2022:
2013:
1980:
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1966:
1955:. Retrieved
1951:the original
1941:
1905:
1902:"Urethritis"
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1840:
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1577:. Retrieved
1572:
1569:"Adenovirus"
1548:. Retrieved
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984:Epidemiology
947:
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819:Adenoviruses
817:
815:
782:pericarditis
747:
744:Other organs
726:
717:otitis media
678:
665:breathing in
634:
605:muscle aches
557:
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447:Adenoviruses
445:
443:
387:muscle aches
347:adenoviruses
345:, caused by
338:
337:
244:Risk factors
236:Adenoviruses
234:
207:pericarditis
95:muscle aches
3133:Coronavirus
2874:Common cold
2786:acute viral
2769:Myocarditis
2613:(probable)
2365:Anal cancer
2023:www.cdc.gov
1785:: 837–852.
1573:www.cdc.gov
1544:www.cdc.gov
1437:www.cdc.gov
1400:www.cdc.gov
1082:www.cdc.gov
974:lung volume
970:scar tissue
923:symptomatic
774:myocarditis
713:conjunctiva
709:photophobia
685:pharyngitis
679:Adenovirus
613:sore throat
535:symptomatic
484:myocarditis
411:sore throat
355:common cold
199:myocarditis
134:conjunctiva
121:sore throat
107:tonsillitis
3299:Categories
3260:Urogenital
3126:Astrovirus
3086:Adenovirus
2910:SARS-CoV-2
2667:Poliovirus
2542:meningitis
1957:2007-07-03
1906:StatPearls
1062:References
927:supportive
894:See also:
890:Prevention
806:urethritis
786:dark urine
539:supportive
357:, such as
296:Prevention
151:tummy ache
103:tummy ache
3171:RNA virus
3152:DNA virus
3144:Hepatitis
3119:Norovirus
3107:Rotavirus
3101:RNA virus
3080:DNA virus
3026:Esophagus
2954:Influenza
2840:RNA virus
2802:DNA virus
2571:RNA virus
2550:DNA virus
2456:RNA virus
2334:DNA virus
2326:Oncovirus
2219:228935463
2211:0303-9021
2123:1096-9071
1801:1177-5467
1639:1069-3424
1499:240127201
1491:1357-3039
1377:237479412
1351:2320-2890
1006:rotavirus
950:pneumonia
941:Prognosis
917:Treatment
876:influenza
862:Diagnosis
825:Although
798:hepatitis
758:Meningism
733:diarrhoea
597:tiredness
511:influenza
492:hepatitis
439:diarrhoea
375:pneumonia
329:Frequency
320:Prognosis
311:Treatment
282:influenza
223:nephritis
213:hepatitis
175:pneumonia
143:diarrhoea
119:, fever,
87:tiredness
81:General:
37:Specialty
3269:BK virus
3072:diarrhea
2916:COVID-19
2658:Myelitis
2141:35474224
2083:article
2077:Archived
1997:26352001
1914:30725967
1819:32256043
1755:32773498
1657:27486739
1579:23 April
1471:Medicine
1410:23 April
1404:Archived
1369:34506970
1025:adenoids
868:PCR test
839:adenoids
794:jaundice
770:lymphoma
737:vomiting
693:rhinitis
661:crackles
609:headache
503:PCR test
435:vomiting
391:headache
266:PCR test
221:Kidney:
147:vomiting
99:headache
49:Symptoms
3022:Pharynx
2526:Central
2271:D000257
2132:9088497
2005:5370331
1810:7094151
1746:8286627
1648:7171713
1360:9133246
1019:History
931:Steroid
856:obesity
790:itching
657:wheezes
427:earache
419:red eye
383:fatigue
249:Endemic
211:Liver:
197:Heart:
191:Brain:
2686:HTLV-I
2631:Rabies
2481:HTLV-I
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882:, and
780:, and
617:glands
601:chills
583:, and
577:coryza
517:, and
452:Spread
373:as in
363:coryza
231:Causes
91:chills
72:wheeze
64:coryza
3282:Mumps
3041:Mumps
3011:Human
2441:MCPyV
2260:B97.0
2215:S2CID
2029:7 May
2001:S2CID
1938:from
1550:7 May
1495:S2CID
1443:7 May
1373:S2CID
1231:7 May
1190:7 May
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569:fever
433:with
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2393:KSHV
2266:MeSH
2207:ISSN
2164:ISBN
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2577:MeV
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2462:HCV
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2354:HPV
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2251:ICD
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2127:PMC
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