Knowledge

Cellosaurus

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Core Data Resource as well as an IRDiRC's Recognized Resource. It is the contributing resource for cell lines on the Resource Identification Portal. As of December 2022, it contains information for more than 144,000 cell lines.
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and age of donor (patient or animal), important sequence variations, web links, publication references and cross-references to close to 100 different databases, ontologies, cell collections and other relevant resources.
336:) and finite life cell lines when those are distributed and used widely. The Cellosaurus provides a wealth of manually curated information; for each cell line it lists a recommended name, synonyms and the 372:, the Cellosaurus keeps track of problematic cell lines, including all those listed in the International Cell Line Authentication Committee (ICLAC) tables. For 385: 617: 972: 1438: 658: 475: 1433: 1237: 548: 965: 317: 143: 63: 395:
The Cellosaurus encyclopedia is widely recognized as an authoritative source for cell line information, providing
685:"Decision letter: Incidences of problematic cell lines are lower in papers that use RRIDs to identify cell lines" 41: 34: 1464: 958: 369: 1459: 353: 380:(STR) profile information. Since July 2018, cell lines in the Cellosaurus are represented as items in 723: 610: 208: 524: 352:
cell lines), the transformant used to immortalise a cell line, transfected or knocked-out genes,
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Ong, Edison; Sarntivijai, Sirarat; Jupp, Simon; Parkinson, Helen; He, Yongqun (December 2017).
329: 106: 1474: 1469: 1132: 1107: 1087: 710: 384:. In March 2020, the Cellosaurus created a page containing cell line information relevant to 739:"The ghosts of HeLa: How cell line misidentification contaminates the scientific literature" 1352: 1162: 1112: 750: 8: 1267: 1137: 806:"Comparison, alignment, and synchronization of cell line information between CLO and EFO" 377: 333: 313: 262: 945: 754: 1428: 1382: 1362: 1347: 1172: 1167: 899: 864: 840: 805: 781: 738: 698: 451: 426: 178: 586: 1367: 1247: 1102: 904: 886: 845: 827: 786: 768: 702: 500:"Rhea, Reactome and Cellosaurus acquire ELIXIR's highest quality label for databases" 456: 396: 389: 1092: 894: 876: 835: 817: 776: 758: 688: 446: 438: 349: 254: 249: 45: 1377: 1342: 763: 234: 138: 40:
It may require cleanup to comply with Knowledge's content policies, particularly
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Since many cell lines used in research have been misidentified or
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of origin. Other types of information include standardised
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Hattori, Emi; Oyama, Rieko; Kondo, Tadashi (2019-02-13).
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Horbach, Serge P. J. M.; Halffman, Willem (2017-10-12).
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A major contributor to this article appears to have a
659:"RRIDs: How did we get here and where are we going?" 312:, which attempts to document all cell lines used in 683:Groll, Helga; Rodgers, Peter A, eds. (2018-11-01). 862: 427:"The Cellosaurus, a cell-line knowledge resource" 1451: 736: 635:"Cellosaurus - SARS-CoV-2 relevant information" 966: 525:"New IRDiRC Recognized Resource: Cellosaurus" 420: 418: 416: 682: 424: 376:as well as some dog cell lines, it provides 973: 959: 413: 332:, naturally immortal cell lines (example: 209:ftp://ftp.expasy.org/databases/cellosaurus 1439:Timeline of biology and organic chemistry 898: 880: 839: 821: 780: 762: 692: 450: 64:Learn how and when to remove this message 16:On-line knowledge resource on cell lines 980: 1452: 1434:Nobel Prize in Physiology or Medicine 954: 931:Introductory video on the Cellosaurus 549:"RRID | Searching in Cell Lines" 96:: a knowledge resource on cell lines 18: 13: 431:Journal of Biomolecular Techniques 295:Yes - individual cell line entries 14: 1486: 919: 473: 318:Swiss Institute of Bioinformatics 144:Swiss Institute of Bioinformatics 623:from the original on 2016-12-20. 44:. Please discuss further on the 23: 936:GitHub directory of Cellosaurus 856: 797: 730: 676: 651: 627: 603: 579: 555: 541: 517: 492: 467: 437:([Epub ahead of print): 1–14. 1: 406: 764:10.1371/journal.pone.0186281 223:https://api.cellosaurus.org/ 7: 10: 1491: 354:microsatellite instability 1421: 988: 946:Record in Identifiers.org 941:Record in FAIRsharing.org 823:10.1186/s12859-017-1979-z 289: 281: 271: 261: 248: 243: 233: 228: 214: 204: 188: 172: 167: 157: 149: 137: 132: 112: 100: 89: 84: 316:. It is provided by the 277:4 to 6 releases per year 694:10.7554/elife.41676.020 443:10.7171/jbt.18-2902-002 330:immortalised cell lines 1048:Biological engineering 718:Cite journal requires 563:"Expasy - Cellosaurus" 1133:Developmental biology 1108:Computational biology 1088:Cellular microbiology 425:Bairoch Amos (2018). 42:neutral point of view 1465:Biological databases 1353:Reproductive biology 1238:Mathematical biology 1163:Evolutionary biology 1113:Conservation biology 882:10.3390/cells8020157 334:embryonic stem cells 1138:Ecological genetics 982:Branches of biology 755:2017PLoSO..1286281H 639:www.cellosaurus.org 388:in response to the 378:short tandem repeat 328:Its scope includes 314:biomedical research 81: 1429:History of biology 1363:Structural biology 1348:Relational biology 1173:Generative biology 1168:Freshwater biology 810:BMC Bioinformatics 397:unique identifiers 179:Flat file database 79: 1460:Molecular biology 1447: 1446: 1368:Synthetic biology 1248:Molecular biology 1103:Cognitive biology 399:and as source of 390:COVID-19 pandemic 344:terminology (for 299: 298: 74: 73: 66: 37:with its subject. 1482: 1093:Chemical biology 975: 968: 961: 952: 951: 913: 912: 902: 884: 860: 854: 853: 843: 825: 801: 795: 794: 784: 766: 749:(10): e0186281. 734: 728: 727: 721: 716: 714: 706: 696: 680: 674: 673: 671: 670: 655: 649: 648: 646: 645: 631: 625: 624: 622: 615: 607: 601: 600: 598: 597: 583: 577: 576: 574: 573: 559: 553: 552: 545: 539: 538: 536: 535: 521: 515: 514: 512: 511: 496: 490: 489: 487: 486: 471: 465: 464: 454: 422: 350:genetic disorder 320:(SIB). It is an 255:Creative Commons 200: 197: 195: 82: 78: 69: 62: 58: 55: 49: 35:close connection 27: 26: 19: 1490: 1489: 1485: 1484: 1483: 1481: 1480: 1479: 1450: 1449: 1448: 1443: 1417: 1378:Systems biology 1343:Quantum biology 984: 979: 922: 917: 916: 861: 857: 802: 798: 735: 731: 719: 717: 708: 707: 681: 677: 668: 666: 657: 656: 652: 643: 641: 633: 632: 628: 620: 613: 609: 608: 604: 595: 593: 585: 584: 580: 571: 569: 561: 560: 556: 547: 546: 542: 533: 531: 523: 522: 518: 509: 507: 498: 497: 493: 484: 482: 472: 468: 423: 414: 409: 291: 282:Curation policy 273: 192: 139:Research center 102: 76: 70: 59: 53: 50: 39: 28: 24: 17: 12: 11: 5: 1488: 1478: 1477: 1472: 1467: 1462: 1445: 1444: 1442: 1441: 1436: 1431: 1425: 1423: 1419: 1418: 1416: 1415: 1410: 1405: 1400: 1395: 1390: 1385: 1380: 1375: 1370: 1365: 1360: 1355: 1350: 1345: 1340: 1335: 1330: 1325: 1320: 1315: 1310: 1305: 1300: 1295: 1290: 1285: 1280: 1275: 1270: 1265: 1260: 1255: 1250: 1245: 1240: 1235: 1233:Marine biology 1230: 1225: 1220: 1215: 1210: 1205: 1200: 1195: 1190: 1185: 1180: 1175: 1170: 1165: 1160: 1155: 1150: 1145: 1140: 1135: 1130: 1125: 1120: 1115: 1110: 1105: 1100: 1095: 1090: 1085: 1080: 1075: 1070: 1065: 1060: 1055: 1050: 1045: 1043:Bioinformatics 1040: 1035: 1030: 1025: 1020: 1015: 1010: 1005: 1000: 995: 989: 986: 985: 978: 977: 970: 963: 955: 949: 948: 943: 938: 933: 928: 921: 920:External links 918: 915: 914: 855: 796: 729: 720:|journal= 675: 650: 626: 602: 591:web.expasy.org 578: 567:web.expasy.org 554: 540: 516: 491: 466: 411: 410: 408: 405: 306:knowledge base 297: 296: 293: 287: 286: 283: 279: 278: 275: 269: 268: 265: 259: 258: 252: 246: 245: 241: 240: 237: 231: 230: 226: 225: 219: 212: 211: 206: 202: 201: 190: 186: 185: 176: 170: 169: 165: 164: 159: 155: 154: 151: 147: 146: 141: 135: 134: 130: 129: 116: 110: 109: 104: 98: 97: 91: 87: 86: 72: 71: 31: 29: 22: 15: 9: 6: 4: 3: 2: 1487: 1476: 1473: 1471: 1468: 1466: 1463: 1461: 1458: 1457: 1455: 1440: 1437: 1435: 1432: 1430: 1427: 1426: 1424: 1420: 1414: 1411: 1409: 1406: 1404: 1401: 1399: 1396: 1394: 1391: 1389: 1386: 1384: 1381: 1379: 1376: 1374: 1371: 1369: 1366: 1364: 1361: 1359: 1356: 1354: 1351: 1349: 1346: 1344: 1341: 1339: 1336: 1334: 1331: 1329: 1326: 1324: 1321: 1319: 1316: 1314: 1313:Phylogenetics 1311: 1309: 1306: 1304: 1301: 1299: 1296: 1294: 1291: 1289: 1286: 1284: 1281: 1279: 1276: 1274: 1271: 1269: 1266: 1264: 1261: 1259: 1256: 1254: 1251: 1249: 1246: 1244: 1241: 1239: 1236: 1234: 1231: 1229: 1226: 1224: 1221: 1219: 1216: 1214: 1211: 1209: 1208:Human biology 1206: 1204: 1201: 1199: 1196: 1194: 1191: 1189: 1186: 1184: 1181: 1179: 1176: 1174: 1171: 1169: 1166: 1164: 1161: 1159: 1156: 1154: 1151: 1149: 1146: 1144: 1141: 1139: 1136: 1134: 1131: 1129: 1126: 1124: 1121: 1119: 1116: 1114: 1111: 1109: 1106: 1104: 1101: 1099: 1098:Chronobiology 1096: 1094: 1091: 1089: 1086: 1084: 1081: 1079: 1076: 1074: 1073:Biotechnology 1071: 1069: 1068:Biostatistics 1066: 1064: 1061: 1059: 1056: 1054: 1051: 1049: 1046: 1044: 1041: 1039: 1036: 1034: 1031: 1029: 1026: 1024: 1021: 1019: 1016: 1014: 1011: 1009: 1006: 1004: 1001: 999: 996: 994: 991: 990: 987: 983: 976: 971: 969: 964: 962: 957: 956: 953: 947: 944: 942: 939: 937: 934: 932: 929: 927: 924: 923: 910: 906: 901: 896: 892: 888: 883: 878: 874: 870: 866: 859: 851: 847: 842: 837: 833: 829: 824: 819: 815: 811: 807: 800: 792: 788: 783: 778: 774: 770: 765: 760: 756: 752: 748: 744: 740: 733: 725: 712: 704: 700: 695: 690: 686: 679: 664: 660: 654: 640: 636: 630: 619: 612: 606: 592: 588: 582: 568: 564: 558: 550: 544: 530: 526: 520: 505: 501: 495: 481: 480:www.sib.swiss 477: 474:Dubar, Elsa. 470: 462: 458: 453: 448: 444: 440: 436: 432: 428: 421: 419: 417: 412: 404: 403:information. 402: 398: 393: 391: 387: 383: 379: 375: 371: 366: 363: 359: 358:doubling time 355: 351: 347: 343: 339: 335: 331: 326: 323: 319: 315: 311: 307: 304:is an online 303: 294: 288: 284: 280: 276: 270: 266: 264: 260: 256: 253: 251: 247: 244:Miscellaneous 242: 238: 236: 232: 227: 224: 220: 217: 213: 210: 207: 203: 199: 191: 187: 184: 180: 177: 175: 171: 166: 163: 160: 156: 152: 148: 145: 142: 140: 136: 131: 128: 124: 120: 117: 115: 111: 108: 105: 99: 95: 92: 88: 83: 77: 68: 65: 57: 47: 43: 38: 36: 30: 21: 20: 1475:Cell culture 1470:Cell biology 1358:Sociobiology 1338:Protistology 1303:Photobiology 1298:Pharmacology 1288:Parasitology 1283:Paleontology 1263:Neuroscience 1243:Microbiology 1153:Epidemiology 1123:Cytogenetics 1083:Cell biology 1063:Biosemiotics 1053:Biomechanics 1033:Biogeography 1028:Biochemistry 1023:Bacteriology 1018:Astrobiology 872: 868: 858: 816:(S17): 557. 813: 809: 799: 746: 742: 732: 711:cite journal 678: 667:. Retrieved 665:. 2017-05-11 662: 653: 642:. Retrieved 638: 629: 605: 594:. Retrieved 590: 581: 570:. Retrieved 566: 557: 543: 532:. Retrieved 528: 519: 508:. Retrieved 506:. 2020-12-24 503: 494: 483:. Retrieved 479: 469: 434: 430: 394: 370:contaminated 367: 327: 301: 300: 290:Bookmarkable 285:Yes - manual 272:Data release 205:Download URL 196:.cellosaurus 162:Amos Bairoch 93: 75: 60: 51: 32: 1408:Xenobiology 1403:Virophysics 1373:Systematics 1328:Primatology 1273:Ornithology 1213:Ichthyology 1198:Herpetology 1193:Gerontology 1158:Epigenetics 1118:Cryobiology 1008:Agrostology 998:Aerobiology 993:Abiogenesis 926:Cellosaurus 302:Cellosaurus 216:Web service 174:Data format 94:Cellosaurus 90:Description 80:Cellosaurus 1454:Categories 1393:Toxicology 1388:Teratology 1333:Proteomics 1318:Physiology 1258:Neontology 1223:Lipidology 1218:Immunology 1188:Geobiology 1148:Embryology 1128:Dendrology 1058:Biophysics 1038:Biogeology 875:(2): 157. 669:2021-10-19 644:2022-09-01 596:2020-04-13 572:2021-10-19 534:2021-11-02 529:irdirc.org 510:2021-10-19 485:2021-10-19 407:References 386:SARS-CoV-2 310:cell lines 263:Versioning 181:, OBO and 150:Laboratory 119:Vertebrate 107:Cell lines 101:Data types 1308:Phycology 1293:Pathology 1278:Osteology 1268:Nutrition 1228:Mammalogy 1203:Histology 891:2073-4409 832:1471-2105 773:1932-6203 703:239787612 274:frequency 257:CC BY 4.0 114:Organisms 54:July 2018 46:talk page 1422:See also 1398:Virology 1383:Taxonomy 1323:Pomology 1253:Mycology 1183:Genomics 1178:Genetics 1003:Agronomy 909:30781855 850:29322915 791:29023500 743:PLOS ONE 618:Archived 461:29805321 382:Wikidata 292:entities 103:captured 1413:Zoology 1143:Ecology 1013:Anatomy 900:6406745 841:5763470 782:5638414 751:Bibcode 452:5945021 401:curated 342:disease 338:species 250:License 189:Website 158:Authors 153:CALIPHO 133:Contact 85:Content 1078:Botany 907:  897:  889:  848:  838:  830:  789:  779:  771:  701:  504:ELIXIR 459:  449:  362:gender 346:cancer 322:ELIXIR 239:Search 168:Access 123:Insect 869:Cells 699:S2CID 663:eLife 621:(PDF) 614:(PDF) 374:human 229:Tools 905:PMID 887:ISSN 846:PMID 828:ISSN 787:PMID 769:ISSN 724:help 457:PMID 221:API 198:.org 127:Tick 895:PMC 877:doi 836:PMC 818:doi 777:PMC 759:doi 689:doi 447:PMC 439:doi 348:or 308:on 267:Yes 235:Web 218:URL 194:www 183:XML 1456:: 903:. 893:. 885:. 871:. 867:. 844:. 834:. 826:. 814:18 812:. 808:. 785:. 775:. 767:. 757:. 747:12 745:. 741:. 715:: 713:}} 709:{{ 697:. 687:. 661:. 637:. 616:. 589:. 565:. 527:. 502:. 478:. 455:. 445:. 435:29 433:. 429:. 415:^ 392:. 360:, 356:, 125:, 121:, 974:e 967:t 960:v 911:. 879:: 873:8 852:. 820:: 793:. 761:: 753:: 726:) 722:( 705:. 691:: 672:. 647:. 599:. 575:. 551:. 537:. 513:. 488:. 463:. 441:: 67:) 61:( 56:) 52:( 48:.

Index

close connection
neutral point of view
talk page
Learn how and when to remove this message
Cell lines
Organisms
Vertebrate
Insect
Tick
Research center
Swiss Institute of Bioinformatics
Amos Bairoch
Data format
Flat file database
XML
www.cellosaurus.org
ftp://ftp.expasy.org/databases/cellosaurus
Web service
https://api.cellosaurus.org/
Web
License
Creative Commons
Versioning
knowledge base
cell lines
biomedical research
Swiss Institute of Bioinformatics
ELIXIR
immortalised cell lines
embryonic stem cells

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