1205:
102:
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17:
851:(formation of stones) is a global human health problem. Stones can form in both urinary and gastrointestinal tracts. Related to the formation of stones is the formation of crystals; this can occur in joints (e.g.
741:
from damage by sequestering it within a crystalline structure. This process is mediated by the stress response protein Dps and allows the bacteria to survive varied assaults such as
832:
biocrystallization remains one of the most promising avenues for antimalarial drug development because the drug target is highly specific to the malarial parasite, and outside the
715:
446:
667:
47:
such as processes that dispose of waste compounds, or a pathology. Template mediated crystallization is qualitatively different from
708:
950:
Wolf SG, Frenkiel D, Arad T, Finkel SE, Kolter R, Minsky A (July 1999). "DNA protection by stress-induced biocrystallization".
1051:
701:
784:. To date, the only definitively characterized product of hematin disposal is the pigment hemozoin. Hemozoin is
578:
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406:
207:
796:. Heme biocrystallization has been found in blood feeding organisms of great medical importance including
1235:
1185:
401:
1240:
1171:
688:
635:
1084:
Hempelmann E, Marques HM (September 1994). "Analysis of malaria pigment from
Plasmodium falciparum".
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780:. To avoid destruction by this molecule, the parasite biocrystallizes heme to form
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234:
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93:
24:
was developed in
Germany in the 1930s. For 20 years Chloroquine was a "magic bullet".
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44:
1192:
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1003:"Dps Protects Cells against Multiple Stresses during Stationary Phase"
73:, since many of these organisms use this process to safely dispose of
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Porena M, Guiggi P, Micheli C (2007). "Prevention of stone disease".
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1052:"Biocrystallization: A last-resort survival strategy in bacteria"
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902:"Order in stress - lessons from the inanimate world"
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1165:Order in stress – Lessons from the inanimate world
43:. This may be a stress response, a normal part of
1083:
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893:
709:
994:
943:
1000:
899:
814:. Heme biocrystallization is inhibited by
776:and release high quantities of free toxic
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1050:Frenkiel-Krispin, D.; Minsky, A. (2002).
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57:of biocrystallization are of interest in
15:
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728:Under severe stress conditions the
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20:The biocrystallization inhibitor
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1019:10.1128/JB.186.13.4192-4198.2004
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682:
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1001:Nair S, Finkel SE (July 2004).
447:microbial calcite precipitation
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1:
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407:marine biogenic calcification
1098:10.1016/1056-8719(94)90013-2
900:Kachroo AH (December 2004).
843:
792:and therefore not formed by
7:
1086:J Pharmacol Toxicol Methods
858:
636:Biomineralising polychaetes
402:amorphous calcium carbonate
88:Part of a series related to
10:
1257:
668:Burgess Shale preservation
772:feeding organisms digest
630:Cupriavidus metallidurans
351:Teeth, scales, tusks etc
764:
412:calcareous nannofossils
208:Choanoflagellate lorica
909:Journal of Biosciences
876:Magnetotactic bacteria
855:) and in the viscera.
601:Magnetotactic bacteria
426:oolitic aragonite sand
284:scaly-foot snail shell
80:
25:
19:
1186:Evolutionary biology
31:is the formation of
1062:(6). Archived from
964:1999Natur.400...83W
328:Vertebrate skeleton
118:Mineralized tissues
1236:Chemical pathology
921:10.1007/bf02712104
871:Diatomaceous earth
492:diatomaceous earth
458:Great Calcite Belt
375:Scale microfossils
368:otolithic membrane
279:small shelly fauna
252:echinoderm stereom
128:Biocrystallization
29:Biocrystallization
26:
1241:Biomineralization
1133:10.1159/000104440
866:Biomineralization
794:biomineralization
751:ultraviolet light
726:
725:
656:permineralization
641:Mineral nutrients
566:Mineral evolution
235:foraminifera test
94:Biomineralization
53:crystallization.
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734:Escherichia coli
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606:Magnetoreception
586:Ballast minerals
181:Cephalopod shell
176:Brachiopod shell
123:Remineralisation
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61:efforts against
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272:gastropod shell
240:testate amoebae
230:diatom frustule
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1159:External links
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1013:(13): 4192–8.
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958:(6739): 83–5.
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1066:on 2011-07-25
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394:Calcification
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315:Endoskeletons
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215:Protist shell
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186:cirrate shell
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69:that feed on
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35:from organic
34:
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1231:Cell biology
1210:Paleontology
1124:
1120:
1114:
1092:(1): 25–30.
1089:
1085:
1079:
1068:. Retrieved
1064:the original
1059:
1055:
1045:
1010:
1007:J. Bacteriol
1006:
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827:
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661:petrifaction
628:
616:
611:Microfossils
358:Limpet teeth
338:Ossification
333:Bone mineral
267:chiton shell
152:Exoskeletons
133:Biointerface
127:
65:and against
48:
28:
27:
823:chloroquine
811:Schistosoma
596:Magnetosome
539:phosphorite
505:Other forms
453:calcite sea
220:coccosphere
164:exoskeleton
59:drug design
22:chloroquine
1226:Metabolism
1220:Categories
1070:2008-05-05
888:References
828:Targeting
799:Plasmodium
774:hemoglobin
747:heat shock
191:cuttlebone
160:Arthropod
55:Inhibitors
45:metabolism
39:by living
1127:: 37–46.
1121:Urol. Int
988:204994265
849:Lithiasis
844:Lithiasis
816:quinoline
617:engrailed
534:Phosphate
527:oil shale
421:Aragonite
225:coccolith
67:pathogens
63:lithiasis
41:organisms
1141:17726351
1056:ASM News
1037:15205421
980:10403254
937:13401792
929:15625389
859:See also
838:parasite
821:such as
805:Rhodnius
782:hemozoin
730:bacteria
689:Category
570:In soil
522:alginite
512:Bone bed
247:Seashell
154:(shells)
50:in vitro
33:crystals
1198:Geology
1172:Portals
1149:8068808
1106:7833503
960:Bibcode
834:genetic
790:mineral
559:Related
517:Kerogen
442:Calcite
363:Otolith
196:gladius
169:cuticle
138:Biofilm
111:General
1147:
1139:
1104:
1035:
1028:421617
1025:
986:
978:
952:Nature
935:
927:
788:not a
687:
546:Pyrena
203:Lorica
1145:S2CID
984:S2CID
933:S2CID
905:(PDF)
881:Prion
770:Blood
624:Druse
319:bones
262:nacre
71:blood
1137:PMID
1102:PMID
1033:PMID
976:PMID
925:PMID
853:gout
830:heme
808:and
778:heme
765:Heme
619:gene
380:Tusk
301:Test
75:heme
1129:doi
1094:doi
1023:PMC
1015:doi
1011:186
968:doi
956:400
917:doi
739:DNA
81:DNA
1222::
1143:.
1135:.
1125:79
1123:.
1100:.
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1088:.
1060:68
1058:.
1054:.
1031:.
1021:.
1009:.
1005:.
982:.
974:.
966:.
954:.
931:.
923:.
913:29
911:.
907:.
840:.
825:.
802:,
761:.
759:pH
753:,
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745:,
77:.
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1039:.
1017::
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919::
717:e
710:t
703:v
321:)
317:(
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
